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Quality-Of-Life Outcomes Of Tympanoplasty/Mastoidectomy Operations, Peter Shokr Meglaa, Ahmed Hemdan Eldeeb, Hisham Atef Abada, Yousef Kamel Shabana

Mansoura Medical Journal

Background: Chronic suppurative otitis media (CSOM) impairs quality of life (QoL) via otorrhea, hearing loss, and psychosocial effects, with surgery (tympanoplasty/mastoidectomy) as mainstay treatment despite limited patient-centered outcome data. This study aimed to evaluate QoL changes post-tympanoplasty/mastoidectomy in CSOM using validated tools.

Methods: This prospective study included 50 adults with CSOM at Mansoura University Hospitals. Pre/postoperative assessments included Chronic Otitis Media Outcome Test-15 (COMOT-15), Short Form-36 Health Survey (SF-36), Hearing Handicap Inventory for the Elderly-Screening (HHIE-S), Tinnitus Evaluation Questionnaire (TEQ), Situational Vertigo Questionnaire (SVQ), pure tone audiometry (PTA), and air-bone gap (ABG).

Results: PTA improved from 48.5±10.2 to 28.3±8.4 dB …

Red Cell Distribution Width As A Prognostic Factor And Its Comparison With Lactate In Patients With Sepsis: An Observational Prospective Cohort Study, Ahmed Taha Gad, Ghada Fathy El-Rahmawy, Naglaa Abd El-Latif El-Negeery, Eiad Ahmed Ramzy

Mansoura Medical Journal

Background: Red blood cell distribution width (RDW) is a straightforward and cost-effective parameter that is utilized in laboratory hematology to differentiate anemias. It is indicative of the grade of heterogeneity in erythrocyte volume. This study purpose examine the correlation among the risk of adverse results in patients with sepsis and RDW, as well as to equivalence the mortality discriminative capacity of RDW and lactate levels.

Methods: This observational prospective cohort study was done on 67 sepstic patients aged ≥ 21 years old, both sexes. Patients were owed into two groups according to RDW levels: Group A (n=35): normal RDW …

Diffusion Weighted Magnetic Resonance Imaging In Rectal Cancer, Ebtehal A. Mohamed, Fatma Mohamed Sherif, Wael Abdulghaffar, Ahmed M Fareed, Gehad A. Saleh

Mansoura Medical Journal

Background: Rectal cancer (RC) is a major cancer burden globally as it is among the tumors that are most frequently diagnosed worldwide and a significant contributor to global cancer mortality yearly. Imaging with diffusion weighting (DWI) and Magnetic resonance imaging (MRI) is the best radiological modality for the local staging and restaging of RC due to its excellent soft-tissue contrast and high spatial resolution.

Aim of the work: This study aims to assess the value of DW-MRI in staging and assessing treatment response in patients with RC who received concurrent chemoradiotherapy.

Methods: Forty-two patients with RC diagnoses …

The Potential Role Of Naftidrofuryl Oxalate In Rat Model Of Ulcerative Colitis, Omar Mohsen Elmazny, Ahmed Abdel-Monem Elmetwally, Vivian Boshra, H.M. El-Beltagi, Basma Hamed Othman, Heba Sheta

Mansoura Medical Journal

Background: Ulcerative colitis (UC) is a chronic, recurrent bowel disease characterized by inflammation that leads to superficial damage to the colon wall. The rate of incidence of UC differs from 0.5 to 31.5 per 100,000 subjects annually. The exact cause is still not well-identified. Studies suggest genetic factors, altered immune response, and environmental factors may play a role in the initiation and progression of the disease. Its pharmacological treatment remains unsatisfactory. Aim: To assess the possible protective effect of Naftidrofuryl oxalate (NFT) (praxilene) on intestinal epithelial cells in acetic acid (AA)-induced UC model in rats.  Materials and Methods: sixty female …

Hypoalbuminemia As A Predictive Factor For Acute Kidney Injury In Pediatric Patients Running Title: Hypoalbuminemia In Aki Pediatrics, Kareem El-Saeed El-Maasrany, Ayman Hammad, Hosam Zaghloul, Ahmed Elhusseiny

Mansoura Medical Journal

Aim: Hypoalbuminemia is a well-known risk factor for illness and death, but its role as a particular predictor of acute kidney injury (AKI) is still not fully understood. This study intended to evaluate the role of hypoalbuminemia as a predictive factor for AKI outcome among pediatric patients, regarding hospital stay, kidney replacement therapy and mortality rate.

Subjects and Methods: This prospective observational cohort was conducted on 70 children with AKI divided into two groups: group I (35 AKI children combined with hypoalbuminemia) and group II (35 AKI children without hypoalbuminemia). All participants were subjected to full history taking, clinical examination …

Added Value Of T2 Space Stir In Magnetic Resonance Imaging Evaluation Of Post-Traumatic Brachial Plexus Injury, Nehal Tharwat, Ahmed Mohamed Abdelkhalek, Mohamed Ashraf Abd El-Moniem, Hesham Abdel Fattah Elsobky, Ahmed Alaa El-Din Elagamy

Mansoura Medical Journal

Background: Traumatic brachial plexus injuries (TBPIs) cause severe upper limb disability. Owing to the complex anatomic architecture of the brachial plexus (BP), TBPIs are difficult to diagnose. Magnetic resonance neurography of the BP using three-dimensional isotropic imaging provides excellent background fat suppression and adequate soft-tissue contrast, thereby allowing better delineation of the BP along its pathway. This study aimed to compare image quality between T2-Short tau inversion recovery (T2-STIR) and 3D-transverse relaxation time-sampling perfection with application of optimized contrasts using different flip-angle evolution short tau inversion recovery (3D-T2 SPACE STIR) sequences in cases of TBPIs.

Methods: This study included 44 …

The Role Of Adult Appendicitis Score In Reducing The Negative Appendectomy Rate, Mohamed Mahmoud Mansour El Ghzzawy, Magdy Basheer, Mohamed Balata, Amir A. Fikry

Mansoura Medical Journal

Aim: Approximately 15 – 30% of all acute appendectomies are performed based only on clinical suspicion. A negative appendectomy has a 10–12% morbidity rate, which could be detrimental to patients. The current study aimed to evaluate the effectiveness of adult appendicitis score (AAS) in accurate identification of cases with acute appendicitis.

Patients and Methods: This prospective observational study was conducted on 150 patients who presented with manifestations of acute appendicitis admitted to Mansoura Emergency Hospital.  The AAS was calculated, the decision on appendectomy was solely based on the surgeon’s clinical judgment after taking into consideration all the findings of clinical, …

Evaluation Of Β2-Microglobulin In Patients With Psoriasis Vulgaris Case Controlled Study, Ishraq Mazhar Shaaban, Fatma Faisal El Dakrory, Alshaimaa Hamdi Abd Elmaksoud, Youssef El-Bayoumi Youssef Soliman

Mansoura Medical Journal

Background: Psoriasis is a persistent, immune-mediated dermatological condition influenced by complex genetic architectures and systemic inflammation. This investigation evaluated the diagnostic utility of serum β2-microglobulin β2 as a quantitative indicator for gauging clinical severity in psoriatic patients.

Aim of the work: The primary objective of this investigation was to evaluate the diagnostic utility of serum β2-microglobulin (β2M) as a quantitative biomarker for assessing disease severity in patients with psoriasis vulgaris. Specifically, the study sought to determine the correlation between circulating β2M levels and established clinical parameters, including the Psoriasis Area and Severity Index (PASI), body mass index (BMI), and …

Assessment Of Health-Related Quality Of Life In Pediatric Patients With End Stage Renal Diseases, Nasteho Adan Awil, Ahmed Mahmoud Elrefaey, Abdel-Hady El-Gilany Abdel-Elfattah, Heba Mohamed El-Taher

Mansoura Medical Journal

Background: End-stage renal disease (ESRD) occurs when the glomerular filtration rate falls below 15 mL/min, requiring renal replacement therapy. Despite improved survival, affected children experience significant physical, emotional, and social challenges. Consequently, health-related quality of life (HRQoL) is markedly reduced compared with healthy peers.

Aim: This study aimed to assess health-related quality of life (HRQOL) in pediatric patients with end-stage renal disease (ESRD) and to identify factors associate with the quality of life in pediatric patients with   end stage renal disease (ESRD).

Methods:  All 60 eligible children who were enrolled in the Nephrology Unit at Mansoura University Children's Hospital …

Evaluation Of Cardiac Troponin T And Ischemia-Modified Albumin Changes With Hemodialysis Session In Pediatric Patients With End-Stage Renal Disease, Zeinab Ezz Elden Abass Abd Eldayem, Ashraf Mohammed Abdel Basset, Gehan Attia Abdehakem, Shiama Abdelmgiad, Nermin Yossef Abo Elkheir

Mansoura Medical Journal

Background : Cardiovascular status in dialysis patients is complicated by a wide range of factors that can affect long-term prognosis. Cardiac biomarkers changes with hemodialysis session could affect the cardiac integrity of those patients. Aim of the work: Assess the changes of cardiac ischemic biomarkers (Troponin T and ischemia modified albumin) before and after hemodialysis session in patients with ESRD in pediatric age group and study of correlations of changes with the hemodialysis parameters. Patients and methods: The study included 40 pediatric ESRD patients who were admitted to Pediatric Cardiology Unit, Pediatric Nephrology and Dialysis Unit of Mansoura University Children’s …

Fascia Transversalis Block With Different Volumes Of Local Anesthetic And Its Impact On Postoperative Pain In Major Abdominal Surgery: Prospective Randomized Study, Eman Eltabey Lotfi Taman, Mostafa Mohamed Ali Saied, Khaled Mohy Eldeen El Bahrawy, Abdelrahman Mamdouh El Naggar

Mansoura Medical Journal

Background Effective postoperative analgesia remains crucial in abdominal surgery to reduce physiological stress, improve respiratory function, and enhance recovery. The transversalis fascia plane block (TFPB) has recently emerged as an advantageous technique targeting the T12–L1 nerves responsible for somatic and visceral abdominal innervation. Objective To investigate the analgesic efficacy of different volumes of local anesthetic administered in TFPB and compare their effect on postoperative pain, visceral discomfort, and opioid requirements. Methods Eighty-one adult patients undergoing major abdominal surgery under general anesthesia were randomized into 3 groups: control (systemic analgesia only), lowvolume TFPB (20 mL total), and high-volume TFPB (25 mL …

Diagnostic Performance Of Digital Breast Tomosynthesis In The Characterisation Of Breast Lesions: Correlation With Sono-Mammography And Histopathology., Amira Hamed Megahed, Mona Mahmoud Zaky, Maha Mohamed Bilal

Mansoura Medical Journal

Background: Breast lesions range from benign to malignant, with early detection critical for management. Digital mammography is the standard screening tool but may be limited in dense breasts. Ultrasound (US) aids lesion characterisation, while digital breast tomosynthesis (DBT) reduces tissue overlap, enhancing lesion detection.

Objective: To evaluate the diagnostic performance of digital breast tomosynthesis in the characterisation of breast lesions compared with sono-mammography, using histopathology as the reference standard.

Methods: This prospective study included 33 symptomatic female patients with a mean age (45.4 ± 8.2 years) who presented with symptoms such as palpable breast lumps, Mastalgia and nipple discharge between …

Assessment Of Serum Level Of Lipocalin-2 In Patients With Alopecia Areata, Mohammed S. Sultan, N. M. Darwish, Hosam Abdel Tawab, Asmaa M. Shalaby

Mansoura Medical Journal

Background: Alopecia areata (AA) is a chronic autoimmune disease (AID)-causing non-scarring hair loss (NSHL), mainly on the scalp. It affects about 2% of people worldwide, usually starting in the third or fourth decade. This study aimed to evaluate serum lipocalin-2 levels in AA patients compared to healthy controls (HC), and to examine their correlation with disease severity Methods: This one-year prospective case-control study included 40 AA patients from Mansoura University Hospitals and 40 age- and sex-matched healthy control. Diagnosis was based on typical, well-defined non-inflammatory scalp hair loss (HL) confirmed by dermoscopy. Controls were healthy, with no autoimmune history or …

Comparative Study Between Serum Levels Of Interleukin-19 And Interleukin-38 In The Egyptian Patients With Non-Segmental Vitiligo, Reem Ahmed Al Maaddawy, Mohamed Kh. Selim, Ahmed Fawzi Ismail, Ahmad S. Hasan, Manar Ali Hassan

Mansoura Medical Journal

Background: The precise etiology of vitiligo remains unclear; nonetheless, it is predominantly regarded as an autoimmune disorder. This work aimed to compare serum levels of IL-19 and IL-38 between patients with non-segmental vitiligo (NSV) and healthy controls (HC). Patients and Methods: This study included 88 participants, evenly split into two groups: 44 individuals with non-segmental vitiligo and 44 healthy controls. Both groups underwent full history taking. The Vitiligo Area Severity Index (VASI) score and Vitiligo Disease Activity (VIDA) score were used to assess disease severity and activity. The levels of human IL-19 and IL-38 were also measured.

Results:Serum IL-38 …

A Comparative Study Of Topical 5% 5-Fluorouracil With Needling Versus 100% Trichloroacetic Acid With Needling Versus Needling Alone In Treatment Of Multiple Warts, Nesma Abd-Elmonem Saad, Hassan A. Fayed, Manar Ali

Mansoura Medical Journal

Aim: This study aimed to compare the efficacy and safety of topical 5% 5-Fluorouracil (5-FU) with Needling versus 100% Trichloroacetic acid (TCA) with Needling versus Needling Alone in treatment of multiple warts.

Methods: This study included a total of 60 patients clinically diagnosed with multiple warts, who were randomly allocated (computer-generated simple randomisation, 1:1:1, concealed in sequentially numbered opaque sealed envelopes) into three equal groups (n=20 per group). The first group received 100% TCA with Needling; the second group received topical 5% 5-FU combined with Needling; the third group underwent Needling alone. The study was single-blinded at the level …

Active Deresuscitation Strategies After Septic Shock: A Scoping Review, Alrefaey K. Alrefaey, Rania E Elbadrawy, Mohamed Aboelela, Mohammed Mamoun

Mansoura Medical Journal

Background: Fluid overload in septic shock patients is linked to higher morbidity and mortality. After the stabilization phase, fluid restriction may not result in the resolution of tissue edema. Active deresuscitation refers to the use of diuretics or ultrafiltration for the removal of excess fluids. Objectives: This review explores the current practices applied for the active deresuscitation strategies after stabilization of septic shock patients.  Search strategy: A literature search was performed through the following databases: Medline, PubMed, Google Scholar, Web of Science, and Scopus for relevant studies from 2015 to January 2026. Selection criteria:  The selected articles included …

Laparoscopic Versus Open Redo Anti-Reflux Surgery, Mohamed Barkok, Mohammed Said, Ahmed Shehta, Abdel-Raouf El-Geidie

Mansoura Medical Journal

Background

Gastroesophageal reflux disease (GERD) is common. Laparoscopic fundoplication became the gold standard for GERD surgery after medical treatment failed. If a previous anti-reflux surgery fails, redo surgery requires a thorough review to determine the cause and a skilled surgical team. Choosing the optimal approach during the redo surgeries, whether open or laparoscopic hasn’t been previously illustrated.

Aim

To compare the outcomes of laparoscopic versus open redo anti-reflux surgeries.

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Patients and methods

This study included 28 patients who underwent redo anti-reflux surgery. The patients were divided according to the approach into laparoscopic (n = 11) and open (n = …

Short Term Echocardiographic And Clinical Assessment Of Aortic Valve Neo-Cuspidization (Ozaki Procedure) In Comparison With Mechanical Aortic Valve Replacement, Amr Mohamed Ahmed Elshabrawy, Mohamed A. Gabr, Eid M Daoud, Mohammed Sanad, Sherif Arafa

Mansoura Medical Journal

Background: Aortic valve neo-cuspidization (AVNeo, Ozaki procedure) has emerged as an alternative to conventional aortic valve replacement, aiming to preserve native aortic root dynamics and improve postoperative hemodynamics. The replacement of the aortic valve presents challenges because both biological and mechanical prostheses have notable limitations.

Aim: To evaluate the short-term clinical and echocardiographic outcomes of aortic valve neocuspidization (Ozaki procedure) compared with mechanical aortic valve replacement (AVR) in patients with isolated aortic valve disease.

Patients and methods: This prospective comparative observational study included 42 adult patients with isolated aortic valve disease. 20 patients underwent AVNeo (Ozaki procedure) and 22 …

Bargaining Inefficiency Due To Mispricing Under Incomplete Information : Evidence From The Bilateral Oligopolistic Containership Time Charter Market, Jaeung Cha

World Maritime University Ph.D. Dissertations

A well-established body of bargaining studies theoretically demonstrates that inherent limitations in observing the counterplayer’s private information give rise to an incomplete information setting in bargaining, leading to efficiency losses associated with mispricing, costly delays, and even bargaining failures. As the shipping market, a business-to-business market in which products are generally heterogeneous and the number of both sellers and buyers is limited by high entry/exit barriers, relies on a bargaining mechanism to determine tailored transaction prices, market pricing is prone to inefficiencies associated with incomplete information. However, the relevant empirical evidence remains underexplored in both the shipping finance and bargaining …

Iuse: A Gamified Virtual Learning Platform For Connected Vehicle Applications To Enhance Undergraduate Transportation Education, Tianyu Shen, Di Yang, Kai Sun, Hong Yang, Kun Xie, Mansoureh Jeihani

Civil & Environmental Engineering Faculty Publications

Emerging transportation technologies are rapidly reshaping transportation systems and industry practice. However, most transportation undergraduate curricula still emphasize foundational topics such as geometric design, travel demand forecasting, pavements, and soil properties, typically delivered through lecture-centric instruction. While these subjects remain essential to the discipline, they do not fully reflect the pace of technological change or provide sufficient opportunities for experiential learning with modern tools and data. This gap limits students’ exposure to CV concepts and their ability to translate theory into practice.

Focusing on a key emerging technology, connected vehicles (CVs), this paper bridges the above gap by introducing a …

The Biosynthesis Of The Natural Product N-Nitroglycine, Gabriel Padilla

Graduate Studies Theses and Dissertations 2026

N-Nitroglycine (NNG) is a nitramine [R(R′)N–NO2; R′=H or alkyl] natural product (NP) produced by certain actinomycetes, such as Streptomyces noursei. At the beginning of this project, the biosynthesis of this NP was unknown. The goal was to determine how NNG and its nitramine moiety are enzymatically formed. This could lead to the discovery of novel nitramine NPs with diverse applications as well as alternative/green synthesis of nitramine explosives. This work begins by examining diverse biochemical N–N bond formation strategies. Nitrogen cycle enzymes, nitration of NPs, kutzneride biosynthesis, the aspartate/nitrosuccinate superfamily, hydrazinoacetic acid (HAA) biosynthesis, and streptozocin biosynthesis are among the …

Cracking The Code Of Ai Autonomy: Examining The Role Of Challenge And Hindrance Appraisals And Ai Literacy In Task Satisfaction, Rujuta Parekar

Graduate Studies Theses and Dissertations 2026

AI is constantly evolving and being rapidly integrated into the workplace. Limited research has examined how this integration is affecting employee outcomes, and particularly the impacts of whether employees are expected or mandated to use AI for their work. The present study utilized the challenge-hindrance framework to examine the effect of autonomy in using AI on task satisfaction through challenge and hindrance appraisal among working adults. Since the ability to understand and use AI can influence how individuals perceive it, the moderating effect of AI literacy on the hypothesized research model is also examined. A multi-wave research design was used …

Advancing Cyber-Physical Security And Resilience Of Modern Power Systems: Intelligent Monitoring, Secure Operation, And Resilient Recovery, Md Moshiur Rahman

Graduate Studies Theses and Dissertations 2026

Modern power distribution systems are rapidly evolving into cyber-physical, DER-rich, and data-driven networks that rely on extensive sensing, communication, automation, grid-edge intelligence, and operator decision support. While this transformation improves flexibility, observability and controllability, it also expands the cyber-attack surface and increases the risk that cyber intrusions can propagate into physical disturbances, compromised DER operation, degraded situational awareness, and interrupted service continuity. This dissertation advances the cyber-physical security and resilience of modern distribution systems by developing a high-fidelity real-time cyber-physical hardware-in-the-loop testbed using OPAL-RT, EXata CPS, industrial relays, SCADA/RTAC, HMI, and grid-edge devices to emulate realistic DER-integrated distribution grid operation. …

Two-Phase Transcritical Carbon Dioxide Flow At The Microscale For Thermal Management Applications, Soroush Niazi

Graduate Studies Theses and Dissertations 2026

High-power electronic and power-conversion devices now generate heat fluxes that exceed what conventional air- and single-phase-liquid cooling can dissipate, motivating the search for more capable coolants and cooling mechanisms. Carbon dioxide is an attractive candidate for this role: it is inexpensive, non-toxic, and environmentally friendly, and near its critical point its thermophysical properties change rapidly, which raises the heat-transfer coefficient. In addition, a large pressure drop produces strong cooling through the Joule–Thomson effect and phase change, so that the throttling element itself becomes a source of cooling. This dissertation studies the throttling, phase change, and choking of high-pressure carbon dioxide …

Ossabaw 26.075, Morehead State University History Department (Morehead, Ky)

Guarding Ossabaw Island: History and Archaeology of the 47th N.Y.V.I. Camp

Brass "M" or "W" shaped flat wire

Beyond The Square Pulse: Waveform Shape, Eeg Correlates, And The Pursuit Of Natural Sensation In Tens, Jason Whitson

Honors Undergraduate Theses

This study investigates the relationship between electrical stimulus characteristics of shape and charge on evoked sensations and electroencephalogram (EEG) data during multi-waveform transcutaneous electrical nerve stimulation (TENS) of the median nerve. Neuromodulation methods have traditionally had little control over the location and quality of their associated evoked sensation (e.g., electric, vibration, touch). This experiment utilized five unique stimulus waveforms during TENS stimulation. EEG data were collected concurrently to provide an introductory objective measure of the neural responses underlying these sensory changes. Eleven participants completed three tasks (thresholding, super-threshold stimulation, two-alternative forced choice) using a two-electrode TENS approach. Stimulus waveforms were …

Faculty Fellowships: Knot Theory In The Bay Area, Anthony Bosman

Faculty Publications

No abstract provided.

Modern Research Tools Supporting Science At Andrews University, Peter Lyons, Henry Navarro

Faculty Publications

No abstract provided.

Can You Hear Me Now?, Daniel Gonzalez, Amanda Moore

Faculty Publications

No abstract provided.

Existence, Nonexistence And Uniqueness Of Positive Solution To A General Elliptic System With Fixed Or Perturbed Growth Rates, Joon Hyuk Kang, Noah Koliadko

Faculty Publications

No abstract provided.