Digital Commons Network^™

Sync_Hub, Jose Luis Álvarez Quesada

Grado en Diseño de Interiores

SYNC_HUB, un proyecto que propone la reutilización de un edificio existente para convertirlo en un ecosistema destinado a la creación musical contemporánea. La intervención parte del respeto hacia la arquitectura preexistente, evitando transformaciones irreversibles y apostando por un sistema modular construido en seco que se inserta en el edificio como una nueva infraestructura independiente. Más allá de la incorporación de un programa funcional, el proyecto plantea una reflexión sobre la relación entre patrimonio, arquitectura y cultura contemporánea. La propuesta entiende el edificio como un soporte capaz de acoger nuevas formas de uso sin perder su identidad, estableciendo un diálogo entre …

Osmosis “Where Nature Encourages Becoming”, Jimena Cuevas Tello

Grado en Diseño de Interiores

Osmosis proposes the transformation of “Casa del Marqués de Villora,” designed by Rafael Bergamín, into a cultural and recreational centre dedicated to art, nature, and thought. Located on Calle Serrano in Madrid, the project reimagines the historic building as a “living ecosystem” where visitors can engage with culture while reconnecting with themselves and the environment. The project creates an opportunity to provide not only functional spaces but also spaces capable of supporting reflection, learning, creativity, and renewal in a contemporary city such as Madrid, where there is constant movement, stimulation, and acceleration that often leave little room for contemplation and …

Atmosphaera, Esther Marín Rico

Grado en Diseño de Interiores

Necesidad de abordar la transformación interior integral de la Casa del Marqués de Villora, adaptándola a un nuevo uso contemporáneo sin perder la sensibilidad hacia su valor arquitectónico y cultural. El propósito general consiste en reinterpretar la vivienda desde el respeto a su identidad racionalista, garantizando al mismo tiempo su adecuación funcional a las necesidades actuales.

El proyecto incorpora además el diseño integral del nuevo espacio interior, abordar la organización espacial, la selección de materiales y acabados, el tratamiento de la iluminación, la elección de mobiliario original o reinterpretado del periodo y la inclusión de criterios de sostenibilidad y eficiencia …

Golden Symbiosis, Marta Susperregui Muñoz

Grado en Diseño de Interiores

The concept of Golden Symbiosis emerges from the desire to redefine the relationship between aesthetics, wellbeing, and nature. The term Golden refers to the therapeutic and symbolic value of bee-derived products such as honey, propolis, royal jelly, beeswax, and pollen. For centuries, these natural substances have been associated with healing, nourishment, and regeneration. Within the project, they form the basis of the clinic’s treatment philosophy while representing a return to more restorative and preventative approaches to skin health. The term Symbiosis refers to a mutually beneficial relationship between different living systems. Applied to this project, it becomes the guiding architectural …

El Faro. Coliving Para Personas Con Ritmos De Vida Nocturnos, Leticia Uzquiano Fernández

Grado en Diseño de Interiores

El proyecto busca transformar la Casa del Marqués de Villora en un coliving capaz de responder a una forma de habitar poco atendida: la de quienes viven, trabajan y descansan en horarios desplazados. La propuesta no parte únicamente de introducir un nuevo programa en un edificio existente, sino de revisar cómo una vivienda puede adaptarse a rutinas distintas, a nuevas formas de convivencia y a necesidades que el modelo doméstico convencional apenas contempla.

El objetivo principal es construir una vivienda compartida que acompañe esos ritmos sin convertirlos en aislamiento. Para ello, el proyecto trabaja con distintos grados de intimidad y …

Bloom By Rowse, Julia Jiménez González

Grado en Diseño de Interiores

BLOOM nace de la esencia de ROWSE: una marca que invita a conectar con uno mismo, a encontrar la calma y a descubrir el placer del autocuidado. Inspirándose en estos valores, el concepto del espacio se construye creando una atmósfera entorno a la geometría más orgánica que existe: el círculo, presente en todos los frascos y productos de la marca. Esta figura, se traslada al diseño de BLOOM en forma de recorridos, volúmenes y detalles circulares, creando un entorno amplio, minimalista y sensorial, pensado para poder experimentar la cosmética más allá del producto.

Entre Mundos, Blanca Sánchez Villarta

Grado en Diseño de Interiores

Usuario: Para el proyecto “entre mundos” se plantea un usuario contemporáneo vinculado al ámbito intelectual, creativo y de investigación, entendiendo la residencia no sólo como un refugio sino como un espacio que estimula la reflexión, la concentración y la percepción sensorial. La propuesta se dirige a residentes que permanecen en la residencia durante periodos prolongados de investigación y producción intelectual, aproximadamente de un año de duración. Durante este tiempo, los usuarios desarrollan proyectos relacionados con disciplinas como arquitectura, arte, diseño, escritura, pensamiento contemporáneo o investigación científica y tecnológica. Gracias a la fusión de disciplinas entre los usuarios se plantea que …

The Third Space, Aitana Ariza Aguilera

Grado en Diseño de Interiores

Today’s children inhabit two worlds: Home, where there is often overprotection or a lack of time, and School, where there are rules and schedules to follow. This project was born to fill the gap between them. “The Third Space” is a childhood territory designed to give children back their autonomy, quality free time, and the right to learn without being taught. It is not a place to “be,” it is a place to “be.”

Escuela Bosque, Maria De Los Milagros Abella Ramírez

Grado en Diseño de Interiores

02.1 The starting problem The conventional school organises learning in a single mode: an adult speaks, a group of same-age children sits and listens. This configuration determines the shape of the space -- rectangular classroom, aligned desks, board at the front -- and the space, in turn, reproduces and reinforces that single configuration. The result is a model that incentivises learning through obligation rather than curiosity. Children learn to comply, not to discover. The design of the conventional classroom is not neutral: it shapes a way of relating to knowledge and to others that reproduces the adult-child hierarchy as the …

The House That Builds A Book, Mercedes Vergara Urquijo

Grado en Diseño de Interiores

The project proceeds from the hypothesis that a house can build a book: architecture does not passively house writing but actively participates in its production through physical and sensory variables, height, light, colour, texture, acoustics, correlated with specific cognitive states in the writing process. This hypothesis draws on Michel Foucault’s theory of heterotopia, on Evidence-Based Design (EBD), on the phenomenology of architecture, and on cognitive-behavioural research into creativity and attention. The theoretical framework that follows sets out, in full, the four bodies of theory the project relies on before turning, from section 2.8 onward, to the resulting programme

Weghaus. Un Viaje Emotivo Y Estructural, Elisa Vallejo Palacios

Grado en Diseño de Interiores

El objetivo de este espacio mediante el diseño es fomentar la creatividad y el descubrimiento a través del juego, creando un lugar donde los niños puedan explorar, experimentar y descubir.

En cuanto a mi proyecto, se ha tomado como referancia el concepto del viaje ya que los niños realizarán diferentes recorridos para acceder a los talleres debido a la estructuración del espacio. Este itinerario comenzaría en la zona pública del edificio y continua a las plantas destinadas a realizar las actividades ubicadas en la planta sótano y en la segunda planta.

El recorrido comienza en sentido horizontal para posteriormenterealizarse en …

La Pecera. Centro Cultural Basado En La Ictiología Y La Cultura Marina, Carla Antón Calvo

Grado en Diseño de Interiores

Este Trabajo de Fin de Grado explora la relación entre arquitectura y ecosistemas marinos, tomando como referencia el Océano Pacífico Central. A través del estudio de sus diferentes zonas, se desarrolla una propuesta espacial que traduce condiciones ambientales en experiencias arquitectónicas. Promueve un diálogo entre el racionalismo y la contemporaneidad de la propuesta. Se busca generar un entorno inmersivo en el que poder aprender creando un espacio con fuerte impacto visual y sensorial peor a su vez respetando la estructura de lo que fue el racionalismo. Se promueve la sostenibilidad gracias el uso de elementos reciclables y sistemas circulares, creando …

Marco, Paula Esparrells Del Sol

Grado en Diseño de Interiores

MARCO propone la transformación de la Casa del Marqués de Villora en un soporte espacial flexible capaz de acoger usos diversos vinculados a marcas, experiencias, talleres y nuevas formas de habitar temporalmente el espacio. La intervención parte del reconocimiento del valor arquitectónico de la preexistencia y de la voluntad de insertar en ella una nueva vida contemporánea, abierta, cambiante y cuidadosamente articulada. Lejos de entender el edificio como un simple contenedor neutro, el proyecto lo asume como una estructura con identidad propia, memoria y capacidad de condicionar positivamente la propuesta. A partir de esta premisa, la intervención desarrolla una relación …

The Outcome Of Primary Anastomosis Without Diversion Versus With Diversion In Colorectal Cancer Surgeries, Ahmed Sameh, Shams Nazem, Ahmed A Monem, Amr F Elalfy

Mansoura Medical Journal

Background: Anastomotic leakage (AL) is the most feared complication after colorectal surgery. It is a very morbid consequence that is associated with higher morbidity, longer hospital stay, higher medical expenses, or even worse functional outcomes. The role of diverting ileostomy (DI) in reducing the incidence of anastomotic leakage is still debatable. Methods: Our study included 95 patients with left sided colon cancer and rectal cancer, 49 patients in the non-ileostomy group and 46 patients in the ileostomy group after resection anastomosis of the primary tumor. The analysis included the following variables: patient-related variables (age, sex, comorbid conditions, ASA score, smoking …

The Relationship Between Acne Vulgaris And Insulin Resistance, Nora Moawad Erian, Nora Mohamed Darwish, Eman Saber Elhennawy, Fatma Faisal El Dakrory

Mansoura Medical Journal

Background Some have hypothesized that resistance to insulin, a condition in which cells become less responsive to insulin, contributes to the development and worsening of acne vulgaris. The study's primary objective was to identify any associations among resistance to insulin and acne vulgaris severity. Methods Forty patients (range: 18–40 years old) with acne vulgaris and forty healthy controls (range: 18–40 years old, sex: X), were included in this case control study. Height as well as weight were the anthropometric metrics. To determine how bad acne is, doctors utilize the Global Acne Grading System. Laboratory testing for insulin resistance was conducted …

Predictors And Outcome Of Sepsis And Septic Shock Induced Acute Kidney Injury In Diabetic Patients: A Prospective Observational Study, Shrouk Essam, Rehab Shaheen Bahram Shaheen, Rasha Mahmoud Prof., Adel I. Abdelsalam

Mansoura Medical Journal

Background: One characteristic of sepsis is the dysregulation of the host's reaction to infection, which can result in potentially fatal organ failure.This work aimed to assess predictors and outcome of sepsis and septic shock induced acute kidney injury (AKI) in diabetic patients. Methods: This prospective observational study included diabetic patients aged over 18 years who were admitted with sepsis or septic shock in the Medical Critical Care Unit of the Specialized Medical Hospital, Mansoura University. All patients were divided into 2 groups:AKI Group (N=74): diagnosed with AKI and No AKI Group (N=26): did not develop AKI. Results: Analysis of risk …

Effect Of High-Dose Vitamin D Supplementation On Serum Sclerostin Levels In Chronic Kidney Disease Patients: A Randomized Controlled Trial, Mohamed A. Hassany, Mariam A. Fawy

Mansoura Medical Journal

Background Vitamin D deficiency and altered bone metabolism are common in patients with chronic kidney disease (CKD). Sclerostin, a key inhibitor of bone formation, has been implicated in CKD–mineral and bone disorder (CKD-MBD), but the impact of high-dose vitamin D supplementation on circulating sclerostin is unclear. This work examined the effect of intramuscular cholecalciferol on serum sclerostin and bone-related markers in CKD patients. Methods This randomized controlled trial involved 128 adult CKD patients (stages 3–5), 18–70 years, both sexes, with vitamin D deficiency. Adults were equally randomized into two groups: the intervention group received intramuscular cholecalciferol (300,000 IU at baseline …

The Diagnostic Value Of Serum Ferritin In Telogen Effluvium, Sara Khaled Mohamed Elbasiouny, Marwa H. Elnagdy, Sherif R. Ismaeil, Fawzia A. Saafan

Mansoura Medical Journal

Background Telogen effluvium (TE) is a common cause of hair loss (HL) in females, characterized by diffuse HL. Iron deficiency has a significant relationship with emotional stress, and anxiety is another prevalent cause for HL. So, our aim was to evaluate the serum ferritin levels among TE patients, compared to healthy controls. Methods This case-control study was conducted on 100 subjects, and they were divided into 2 groups, group (A) included 50 patients with Telogen Effluvium and group (B) included 50 healthy normal volunteers matching for age and sex with the patients. Clinical examination of diffuse shedding and positive pull …

Evaluation Of Neutrophils To Albumin Ratio (Nar) And C-Reactive Protein To Albumin Ratio (Car) As Markers Of Disease Activity In Patients With Ulcerative Colitis, Doaa Salah Abd-El-Fattah, Mohamed Abd El-Maksoud, Salwa M. Abo El-Khair, Ahmed El-Eraky, Amany Hasson

Mansoura Medical Journal

Background Ulcerative colitis (UC) is considered an extensive disease due to the risks of proximal extension, malignant transformation, disability and impaired life quality. This study aimed to explore the role of Neutrophils to Albumin Ratio (NAR) and C - reactive protein to Albumin Ratio (CAR) in evaluation of disease activity in patients with UC. Methods This cross-sectional study included 227subjects classified into two groups; group (I) included 126patients suffering from ulcerative colitis and group (II) included 101 healthy individuals with normal basic laboratory tests matched for age and sex. Estimating disease activity and severity clinically was according to Truelove criteria. …

Chronic Stress And Toxoplasma Gondii Infection: Investigating The Two-Hit Hypothesis On Behavior And Cognition In Chronic Toxoplasmosis Mice Model, Nora Labeeb El-Tantawy

Mansoura Medical Journal

Background: Toxoplasmagondii infects about one third of people around the world and is associated with neuropsychiatric disorders. But not everyone who has it ends up with behavioral symptoms, which is kind of interesting. The study aimed to investigate the two-hit hypothesis, basically testing if chronic stress makes the effects of the infection worse in mice, on behavior and cognition. Methods: Sixty Swiss Webster mice were included in the study divided into four groups (15 for each). Group 1 control, group 2 stressed animals exposed to the chronic unpredictable stress protocol, Group 3 infected with T. gondii, and group 4 received …

Fractional Ablative Co2 Laser Versus Screw Threads In Post-Traumatic Atrophic Linear Scars, Eman Emad Elfeel, Marwa Zohdy Ali, Shereen Ezzalregal Alashry, Sherihan Hassan Allam

Mansoura Medical Journal

Background Scar is the result of the natural healing and reparative process, which are frequently accompanied by a few aesthetic, functional, and social impairments and may negatively affect quality of life. Fractional CO2 laser improves both the pigmentary and textural changes by removing thin layers of skin with minimal thermal damage. Thread lifting technology is a non-surgical facial rejuvenation technology that can minimize postoperative recovery period and scar from the incision Aim To compare the efficacy of fractional ablative CO2 laser therapy versus screw threads in post-traumatic atrophic linear scars. Methods This prospective randomized clinical study included 2 groups; group …

Impact Of Admission Hyperglycemia On In-Hospital Arrhythmia In Medical Critical Illness, Ebrahim Elsayed Tawfik, Afaf Abdel Hafez, Tarek El-Sayed Gouda, Rehab Shaheen Bahram Shaheen

Mansoura Medical Journal

Background Admission hyperglycemia is frequently encountered in critically ill patients, even in the absence of pre-existing diabetes. Acute stress hyperglycemia triggers autonomic activation, oxidative stress, and electrophysiological disturbances that may predispose to cardiac arrhythmias. Aim of work The present study aimed to explore the frequency and type of arrhythmic events among critically ill patients with admission hyperglycemia in medical intensive care units (MICU). Methods: A prospective study was conducted on 354 critically ill ICU patients . They were divided into group A with admission hyperglycemia (>180 mg/dL) and group B with admission normoglycemia (≤180 mg/dL). All patients were subjected …

Evaluation Of The Frequency Of Subclinical Peripheral Neuropathy Among Children And Adolescents With Type 1 Diabetes Mellitus Using Nerve Conduction Studies, Hadeer Ashraf Abdulwahab, Ann A. Abdelkader, Nanees Salem, Bothina Hasaneen

Mansoura Medical Journal

Background: The long-term vascular complications of diabetes mellitus (DM) include nephropathy, retinopathy, neuropathy, and macrovascular diseases, so the aim of this study was to evaluate the frequency of subclinical peripheral neuropathy among children and adolescents with Type 1 DM using nerve conduction studies (NCSs) in relation to diabetesrelated clinical and metabolic parameters. Methods: This cross-sectional study was conducted on 50 children and adolescents with T1D. The patients were divided into 2 groups, symptomatic group who had symptoms or signs of diabetic sensorimotor polyneuropathy (DSPN) and asymptomatic group who had no signs or symptoms of polyneuropathy. NCSs were conducted and sensory …

Readmission And Reoperation Following Transurethral Incision Of The Prostate For Benign Prostatic Obstruction: A 20-Year Retrospective Review And Analysis, Amr Wael Yehia, Mohamed Hegazy, Ahmed Refat Elnahas, Ahmed Mohamed Elshal

Mansoura Medical Journal

Introduction: Transurethral Incision of the Prostate (TUIP) is a recognized surgical treatment for benign prostatic obstruction (BPO), particularly in patients with smaller glands. While valued for its minimal invasiveness, it is associated with higher medium-term reoperation rates. This study analyzes a 20-year institutional experience to define the rate, timing, causes, and predictors of readmission and reoperation after TUIP. Methods: A retrospective review of 557 patients who underwent TUIP for BPO was conducted. Data collected included demographics, comorbidities, perioperative details and complications graded by the Clavien-Dindo system. Univariate and multivariate logistic regression analyses identified predictors of readmission and reoperation if present. …

Assessment Of Serum Level Of Il-38 In Patients With Non-Segmental Vitiligo And Its Relation To Disease Severity, Zahraa Jafar Ahmed Altaitoon, Al-Shahat Farag Ahmed Sharaf, Hamdy Fouad A. Marzo, Mohammed Samir Sultan

Mansoura Medical Journal

Background: Vitiligo is a common autoimmune disorder (AID) characterized by extensive loss of melanocytes, causing depigmented skin patches. Interleukin-38 (IL- 38), an anti-inflammatory cytokine, has been linked to several autoimmune conditions, but its involvement in vitiligo hasn’t been confirmed. Aim: To measure serum IL-38 levels in patients with non-segmental vitiligo (NSV) and explores how these levels relate to disease severity and activity. Methods: We conducted a cross-sectional case-control study that included 40 patients with non-segmental vitiligo and 40 healthy individuals matched for age, sex, and BMI. Assessment of disease severity and activity was conducted by using the Vitiligo Area Scoring …

Role Of 16s Rrna Gene And Activin-A In Detection Of Neonatal Sepsis, Reem Gomaa, Walaa Othman Elshabrawy, Nada Mohsen, Mohamed Mofreh

Mansoura Medical Journal

Objective: A bloodstream infection in a newborn less than 28 days is referred to as neonatal sepsis (NS). A novel quick and sensitive markers are required for the early detection of bacterial infections in neonates with sepsis, even if blood culture is a great way to diagnose sepsis because the results are delayed. This study was done to estimate the value of activin-A and molecular method (16S rRNA gene) by PCR as new methods for diagnosis of neonatal sepsis.

Methods: Fifity neonates came to the Mansoura University Children Hospital (MUCH) divided into two Groups: Group І (Sepsis group) …

Comparative Study Between Cervical Disc Arthroplasty And Anterior Cervical Discectomy And Fusion, Samer Samy, Ayman Mohamed Basha

Mansoura Medical Journal

Background: Cervical disc arthroplasty (CDA) has emerged as an alternative to anterior cervical discectomy and fusion (ACDF), aiming to preserve segmental motion and reduce adjacent segment disease (ASD). However, evidence regarding its superiority remains controversial. This study was designed to relate ACDF and CDA following anterior cervical discectomy with respect to safety, efficacy, and impact on patient lifestyle.

Methods: This retrospective comparative study included 36 patients who underwent anterior cervical discectomy between August 2021 and September 2024. Twenty patients underwent ACDF (Group A), and sixteen patients underwent CDA (Group B). Clinical outcomes were assessed using the Visual Analogue Scale (VAS) …

Triglyceride Glucose Index As A Predictor Of Insulin Resistance In Patients With Hypothyroidism, Nadeen El-Nakeeb, Mohammed A. Helaly, Ahmad S. Hasan, Rania Bahriz

Mansoura Medical Journal

Background: Thyroid hormones play a key role in glucose metabolism, and hypothyroidism is frequently associated with impaired insulin secretion, altered glucose disposal, and insulin resistance (IR).

Aim: This study aimed to assess insulin resistance in patients with hypothyroidism using the triglyceride–glucose (TyG) index in comparison with the homeostasis model assessment of insulin resistance (HOMA-IR).

Methods: This case-control study was conducted on 100 participants (50 hypothyroid patients and 50 euthyroid controls), aged 18–60 years. All subjects underwent detailed clinical evaluation, anthropometric measurements, and fasting laboratory investigations including glucose, lipid profile, insulin, TSH, and free T4. Insulin resistance was assessed using TyG …

Impact Of Body Mass Index On Clinical Outcomes In Metastatic Breast Cancer Running Title: Impact Of Bmi On Mbc Outcome, Alaa Abdelrahman Sonbol, Maha Elzaafarany, Ahmed Albehairy, Sherif Refaat

Mansoura Medical Journal

Background: Body mass index (BMI) has been suggested as an important patient-related factor influencing treatment outcomes in breast cancer. This study aimed to evaluate the association between BMI categories and clinical outcomes among patients with metastatic breast cancer (MBC).

Patients and Methods: This retrospective study included 400 patients with MBC. Clinical outcomes assessed included response to first-line treatment, treatment-related toxicity, and status at last follow-up and BMI was calculated using the Quetelet index .

Results: Patients were characterized by a high prevalence of obesity and predominantly good performance status. Disease progression following first-line treatment was the most common …

Role Of Foxl2 Immunohistochemical Marker In Diagnosis Of Ovarian Sex Cord-Stromal Tumors, Correlation With Histopathologic Features And Inhibin Expression, Eman Magdi Hikal, Sylvia Albair Ashamallah, Nadia Abd El-Moniem Nada, Dina Abdallah Ibrahim

Mansoura Medical Journal

Background: Ovarian Sex Cord-Stromal Tumors (SCST) are a broad category of rare neoplasms that exhibit diagnostic challenges. Alpha-inhibin has been traditionally used as immunohistochemical marker (IHC) for SCST, but restrictions as lack of specificity and variability of cytoplasmic staining evolved.  Forkhead box L2 (FOXL2) is one of the earliest markers of ovarian differentiation and is essential for the normal development of granulosa cells and has been identified to be a sensitive and specific marker of Sex Cord-Stromal differentiation.

Aim: Assess FOXL2-IHC expression in different types of SCSTs and correlate its expression with histopathological features and Inhibin-IHC.

Methods: …