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See Jane Lynch, Kate Flannery At Uab's Alys Stephens Center On March 1, Shannon Thomason

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No abstract provided.

Unilateral Cervical Spine Facet Fractures: Radiographic Predictors Of Instability, Erisha Tashakori, Reese Svetgoff, Jacob Siahaan, Norman Zheng, Nicholas Beckmann, James Showery, Ran Lador, Mark L Prasarn

Faculty, Staff and Student Publications

Study design: Retrospective cohort study.

Objective: The purpose of our study is to identify CT characteristics of unilateral cervical spine facet fractures that are predictive of instability on MRI.

Summary of background data: Management of isolated subaxial cervical spine facet fractures is typically based on the neurological status of the patient and perceived stability of the injury. It has been shown that the degree of ligamentous instability can help predict instability and need for surgery, and MRIs are increasingly being used to evaluate these injuries, but not always. While there are studies that evaluate radiographic characteristics of facet fractures on …

Whole Genome Sequence Analysis Of Pulmonary Function And Copd In 44,287 Multi-Ancestry Participants, Peter Orchard, Aabida Saferali, Francois Aguet, Lucinda Antonacci-Fulton, Pallavi P Balte, Traci M Bartz, Wardatul Jannat Anamika, Xiaobo Zhou, Junyi Duan, Jennifer A Brody, Brian E Cade, Martha L Daviglus, Harshavadran Doddapaneni, Shannon Dugan-Perez, Susan K Dutcher, Christian D Frazar, Stacey B Gabriel, Sina A Gharib, Brian D Hobbs, Silva Kasela, Laura R Loehr, Ginger A Metcalf, Donna M Muzny, Elizabeth C Oelsner, Laura J Rasmussen-Torvik, Colleen M Sitlani, Joshua Smith, Tamar Sofer, Hanfei Xu, Bing Yu, David Zhang, John Ziniti, R Graham Barr, April P Carson, Myriam Fornage, Lifang Hou, Ravi Kalhan, Robert Kaplan, Tuuli Lappalainen, Stephanie J London, Alanna C Morrison, George T O'Connor, Bruce M Psaty, Laura M Raffield, Susan Redline, Stephen S Rich, Jerome I Rotter, Edwin K Silverman, Ani Manichaikul, Michael H Cho

Faculty, Staff and Student Publications

Background: Whole genome sequence (WGS) data in multi-ancestry samples supports discovery of low-frequency or population-specific genetic variants associated with chronic obstructive pulmonary disease (COPD) and lung function.

Results: We performed single variant, structural variant, and gene-based analysis of pulmonary function (FEV1, FVC and FEV1/FVC) and COPD case-control status in 44,287 multi-ancestry participants from the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program. We validated findings using the UK Biobank and assessed implicated genes using lung single-cell RNA-seq (scRNA-seq) data sets. Applying a genome-wide significance threshold (P < 5 × 10-9), we replicated known loci and identified novel associations near LY86, MAGI1, GRK7, and LINC02668. Colocalization with gene expression quantitative trait loci (eQTL) from the Lung Tissue Research Consortium highlighted known candidate genes including ADAM19, THSD4, C4B, and PSMA4, which were not identified through other eQTL sources. Multi-ancestry analysis improved fine-mapping resolution (e.g., HTR4 and RIN3). Gene-based analysis identified and replicated HMCN1. In human lung scRNA-seq data sets, lung epithelial cells and immune cell types showed enriched expression, while fibroblasts showed higher expression for HMCN1. CRISPR targeting HMCN1 in IMR90 demonstrated reduced expression of collagen genes.

Conclusions: Large-scale multi-ancestry WGS analysis improves variant discovery and fine-mapping resolution for lung function and …

Rab5c Increases Endothelial Release Of Vwf By Regulating Vesicle Trafficking, D Brian Foster, Nunzio Alcharani, Claudia Gonzalez-Cucharero, William O Osburn, Alanna C Morrison, Alisa S Wolberg, Nicholas L Smith, Marios Arvanitis, Charles J Lowenstein

Faculty, Staff and Student Publications

Background: Abnormal levels of VWF (von Willebrand Factor) are a risk factor for venous thromboembolism (VTE) and bleeding. Genome-wide association studies for VWF have identified novel candidate genes that may regulate VWF levels in humans, including RAB5C (RAS-associated protein RAB5C). We hypothesized that RAB5C regulates VWF release from endothelial cells.

Methods: We studied the effect of RAB5C on vesicle trafficking in human endothelial cells. We performed CRISPR (clustered regularly interspaced short palindromic repeats) interference targeting 2 genetic variants linked to altered VWF levels and evaluated RAB5C expression by reverse transcription-quantitative polymerase chain reaction. We silenced RAB5C or overexpressed RAB5C wild-type, …

Serendipity In Psychiatric Discoveries: Historical Lessons And Future Imperatives For Clinical Observation, Stanley Lyndon, Vineeth P John

Faculty, Staff and Student Publications

Aims and method: Serendipity has driven many of psychiatry's most important treatments, yet contemporary systems may undermine clinicians' ability to notice and develop unexpected therapeutic effects. This selective narrative review synthesises landmark discovery stories, conceptual accounts of serendipity and contemporary case examples to clarify how chance observations become robust advances.

Results: Across historical and modern examples, serendipitous discoveries consistently reflected the interaction of unexpected events with prepared observers working in supportive institutional and research systems. We identify current barriers created by standardised care, funding and trial structures, and professional fragmentation, and outline a multi-level framework for cultivating serendipity through phenomenological …

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

C Elegans As A Tractable Infection Model For The Emerging Fungal Pathogen Candida Auris, Melissa Martinez, Melissa R Cruz, Danielle A Garsin, Michael C Lorenz

Faculty, Staff and Student Publications

Candida auris is an emerging multidrug-resistant fungal pathogen. The genetic factors contributing to the virulence, drug resistance, and stress-tolerant nature of C. auris are mostly unknown. Additional animal models of virulence are needed, especially those amenable to high-throughput analysis. The nematode Caenorhabditis elegans has been validated as an effective tool for studying multiple fungal and bacterial pathogens. We describe here a C. elegans infection model in which exposure to C. auris is lethal to worms with kinetics similar to killing by Candida albicans; in contrast to C. albicans, C. auris does not form hyphae, indicating distinct virulence mechanisms. …

Bdcd: A Comprehensive Brain Disease Cell-Cell Communication Database, Xinyi Liu, Citu Citu, Gang Qu, Wendao Liu, Nitesh Enduru, Andi Liu, Chia-Hao Tung, Zhongming Zhao

Faculty, Staff and Student Publications

Dysregulated cell–cell communication (CCC) is increasingly recognized as a driver of brain disease pathology, contributing to neuroinflammation, synaptic dysfunction, and neurodegeneration. Nevertheless, existing resources remain limited in brain specificity, regional coverage, and functional annotation. To address this gap, we develop the Brain Disease Cell-cell communication Database (BDCD), the first comprehensive resource focused on CCC networks across major brain diseases. BDCD integrates 38 manually curated datasets, comprising 8 519 425 single cells from single-cell RNA-seq studies and 140 744 spots from spatial transcriptomic maps, spanning 14 brain regions and 13 canonical cell types covering Alzheimer’s disease, Parkinson’s disease, schizophrenia, bipolar disorder, …

Re: Utility Of Routine 24-Hour Electrocardiographic Holter Monitoring For Detecting Atrial Fibrillation In Patients Admitted With Acute Stroke Syndromes, Sinda Zarrouk, Josef Finsterer

Sultan Qaboos University Medical Journal

No abstract provided.

Reliability Of Approaches For Measuring Soil Organic Carbon And Implications For Results-Based Payments For Smallholder Carbon Farming, Friederike Schilling, Dennis Beesigamukama, Chrysantus M. Tanga

All Peer-Reviewed Publications

Soil organic carbon (SOC) measurement is critical for result-based payments for carbon sequestration in agriculture. This study examined (i) the consistency of SOC measurements from a portable near-infrared (NIR) spectroscopy soil scanner and laboratory analyses (Walkley-Black method) using samples from 151 plots across Western Kenya, and (ii) explored the implications of measurement error for SOC stock change estimates in group-based carbon farming schemes. Scanner predictions showed a weak correlation with laboratory results (R² = 0.10–0.11; RMSE = 5.6–7.1 g/kg). Comparing results between the two laboratories showed only moderate agreement (R² = 0.34) with a systematic bias of 7.5 …

Comparing And Optimizing Hollow Fibre And Flat Sheet Vacuum Membrane Distillation, Hamed Kariman, Mehdi Khiadani, Hussein A. Mohammed

Research outputs 2022 to 2026

Membrane Distillation (MD) systems have the potential to tackle the growing global water demand. Within various MD systems, Vacuum Membrane Distillation (VMD) systems are particularly important in addressing this issue. Hollow Fibre VMD (HF-VMD) and Flat Sheet VMD (FS-VMD) are the two main configurations of VMD systems, where limited studies are available on their comparison and optimisation under identical operational conditions. This study firstly charts the mathematical modelling of HF-VMD and FS-VMD systems that have been developed, accounting for the amount of flux, Gain Output Ratio (GOR), Temperature Polarisation Coefficient (TPC), and Specific Thermal Energy Consumption (STEC) of both configurations …

20260115: Executive Assistant To The President, 1987-1996, President's Office

Guides to University Archives

These items include materials from the Office of the President at Marshall University from 1987-1996. Items were received in 1996 or thereabouts and include information from the President's Executive Assistant. Items contain Economic Adjustment Programs, MU's CRP Annual Reports, a proposal for Flexible Manufacturing Center for MURC, and Coal Road (survey of southern WV mining and tourism potential). Lots of economic development materials otherwise. This is not an exhaustive list, but the attached inventory will give a broad overview of what is contained in each of the boxes.

Neural Rewiring Of Resilience: The Effects Of Combat Deployment On Functional Network Architecture, Noga Yair, Tom Zalmenson, Omer Azriel, Dana Shamai-Leshem, Yaron Alon, Niv Tik, Lucian Tetse-Laur, Ariel Ben-Yehuda, Daniel Samuel Pine, Anderson M. Winkler, Ido Tavor

School of Medicine Publications

Background: Although combat-deployed soldiers are at high risk for developing trauma-related psychopathology, most will remain resilient for the duration and aftermath of their deployment tour. The neural basis of this type of resilience is largely unknown, and few longitudinal studies exist on neural adaptation to combat in resilient individuals for whom a pre-exposure measurement was collected. Here, we delineate changes in the architecture of functional brain networks from pre- to postcombat in psychopathology-free, resilient participants.

Methods: Tier 1 infantry recruits (n = 50) participated in this longitudinal, functional magnetic resonance imaging study together with a comparison group of university students …

2026 January 15 - From My Notepads Newsletter, Office Of The President, East Tennessee State University, Brian Noland

From My Notepads: A Newsletter from President Brian Noland

No abstract provided.

2026-01-15 Guidelines For Portfolio Managers, Morehead State University. Faculty Senate.

Faculty Senate Records

Guidelines for Portfolio Managers presented to the Faculty Senate on January 15, 2026.

2026-01-15 Faculty Feedback To Fep Results, Morehead State University. Faculty Senate.

Faculty Senate Records

Faculty feedback to FEP results, submitted to the Faculty Senate on January 15, 2026.

2026-01-15 Next Steps For Fep Checklist, Morehead State University. Faculty Senate.

Faculty Senate Records

The next steps for the FEP Checklist submitted to the Faculty Senate on January 15, 2026.

Chasing Disinfection Byproducts Through The Pipes: How 66 Dbps Change Over Time In Chlorinated Vs. Chloraminated Distribution Systems, Erik Niehaves, Patrick T. Justen, Ashley A. Perkins, Alexandria L.B. Forster, Caroline O. Granger, Susan D. Richardson

Faculty Publications

While disinfection byproducts (DBPs) are typically measured at drinking water treatment plants, levels can change dramatically within the distribution system before reaching the consumer. In this study, the spatio-temporal trends of 66 DBPs across 9 different classes were examined in two drinking water distribution systems with similar source waters, but different pretreatments and residual disinfectants. One system uses residual chlorine in the distribution system, and the other uses chloramine, allowing for examination of how DBP concentrations change over time in distribution systems with different residual disinfectants. Four routes were sampled for each system with six time points over three days …

St. Ann's Apartments Llc V. Pickett

All Decisions

In this holdover proceeding, the landlord sought possession after the tenant of record, the respondent's cousin, passed away, alleging the respondent's license expired. The tenant asserted succession rights as a non-traditional family member, arguing emotional and financial commitment and interdependence. Despite limited documentary evidence and contrary testimony from the landlord's superintendent, the court found the tenant's and the deceased's brother's testimony credible. The evidence demonstrated the tenant resided in the apartment as a primary residence for over two years and provided extensive care and support to the ailing tenant of record. The court granted succession, dismissing the proceeding and ordering …

Sustainability In Undergraduate Nursing Clinical Simulation: A Mixed Methods Study Exploring Attitudes, Knowledge And Practices, Bangyun Wang, Louise Sheehy, Astrid Frotjold, Tamara Power, Gemma Saravanos

Individual Open Access Articles

Climate change is among the greatest of threats to human health. Paradoxically the health system is a contributor to planetary degradation through emissions and waste. Climate change and sustainability are important issues for the nursing profession. We explored the impact of an education module with embedded sustainability principles in the context of clinical simulation. This mixed methods study used pre- and post-intervention waste audits and student surveys to explore attitudes, knowledge and practices relating to climate change and sustainability. The intervention, a digital clinical simulation education module, included three themes: 1) professional conduct, 2) work health and safety, 3) resource …

The Relevance Of Climate Change And Sustainability In Nursing Education: A Cross-Sectional Study Of Students’ Perspectives, Jennie Aronsson, Marie Elf, Paul Warwick, Riccardo Lomartire, Anna Anåker

Individual Open Access Articles

Background: As climate change continues to challenge global health, nursing education must evolve to prepare future nurses for the impacts on care delivery and promote sustainable practices within the healthcare system which is itself a contributor to the climate crisis through emissions and waste. In this study we aimed to i) explore undergraduate nursing students’ attitudes towards and awareness of climate change and sustainability issues and its inclusion in nursing education at a Swedish university, and ii) explore differences in awareness and attitudes across student groups in different semesters.

Methods: In this cross-sectional descriptive research study, nursing students from six …

Single-Valued Neutrosophic Pessimistic Multi-Granulation Rough Set Model Based On (A,B,C)-Cut Relations And Its Applications, Xu-Xi Wu, Hu Zhao, Qiao-Ling Song, Xiong-Wei Zhang

Neutrosophic Systems with Applications

To address uncertainty in multi-source data, this paper proposes a single-valued neutrosophic pessimistic multi-granulation rough set (P-SVN-MGRS) model based on (a,b,c)-cut relations. In this framework, each neutrosophic relation is characterized by three membership-degree functions: T(x,y), I(x,y), and F(x,y). These functions correspond to truth-membership, indeterminacy, and falsity, respectively. The (α,β,γ)-cut relation employs parameters α,β,γ∈(0,1] as thresholds for the three functions. A pair (x,y) belongs to …

Synergistic V2ctₓ Mxene–Pani Hybrid With Expanded Interlayers For Ultrastable And High-Rate Pseudocapacitive Energy Storage, Amideddin Nouralishahi, Maryam Sharifi Paroushi, Mansour Razavi, Amarachi Clare Nnachor, Harish Singh, Manashi Nath

Chemistry Faculty Research & Creative Works

Recently, MXene-conducting polymer hybrids have emerged as promising electrode materials for sustainable energy storage applications, owing to their impressive electrochemical properties. Herein, we report the synthesis of vanadium carbide MXene nanoparticles (V2CT_x-MXene) using innovative Spark Plasma Sintering (SPS) technology followed by exfoliation steps. The V2CT_x nanoparticles were incorporated with PANI (MXene-PANI) by electrochemical polymerization of aniline monomers in the presence of V2CT_x nanolayers, to be used as a highly efficient material for charge storage application. PANI nanofibers form a conductive and porous architecture, which intercalates the V2CT_x nanoflakes. The resulting structure increases the interlayer spacing …

Energetics Analysis Of Solitary Waves Using A Multi-Layer Model, Hunter Boswell, Frank D. Han, Guirong Yan, Wouter Mostert

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

This study investigates the performance of a vertically-Lagrangian multi-layer model on numerically simulating shoaling and breaking two-dimensional solitary waves during both the breaking and post-breaking processes. The energy dissipation of the breaking event for the multi-layer waves is analyzed and compared to prior direct numerical simulation work with the same bathymetric and wave cases. It shows very similar data collapse to shallow-water inertial theory. For post-breaking behavior, bore characteristics are compared to an experimental study of bores formed from breaking solitary waves and similar results are found. While the multi-layer method was not found to behave sufficiently well for direct …

Desert Plant Endophyte Genome Database: A Curated Repository Of Endophytic Bacterial Genomes Across Arid Ecosystems, Sabiha Parween, Arun Prasanna Nagarajan, Amal K. Alghamdi, Abdul Aziz Eida, Feras F. Lafi, Luma Albanna, Nida Salem, Barakat Abu-Irmaileh, Zaid A. Pirzada, Shahid Siddique, Ruben Garrido-Oter, Paul Schulze-Lefert, Maged M. Saad, Heribert Hirt

All Works

Microbial communities associated with desert plants play a pivotal role in enhancing host survival under extreme environmental stressors, including drought, salinity, and nutrient limitation. The Desert Plant Endophyte Microbial Collection is one of the largest curated repositories of 2500 cultivable endophytic bacteria isolated from 23 native desert plant species across Saudi Arabia, Jordan, and Pakistan. Representing a broad spectrum of arid microhabitats from inland deserts and mountain wadis to coastal mangroves and date palm oases, the collection supports integrative studies on microbial ecology and plant-microbe interactions in water-limited ecosystems. A central component of this initiative is the Desert Plant Endophyte …

Prevalence Of Hepatitis B Associated Chronic Nephropathy In Baghdad, Iraq For The Year 2023, Ali Abduljabbar Razooqi, Adam Dawoud Salem, Bakri Yousif Nour

Iraqi National Journal of Medicine

Background: The correlation between hepatitis B virus (HBV) and nephropathy presents a significant public health issue in Iraq. Aim: This study systematically investigates the association between hepatitis B surface antigen (HBsAg) serology and chronic kidney disease among residents of Baghdad, Iraq. Methods: We evaluated the clinical characteristics and serologic profiles of 609 patients with adult-onset HBV-related membranous nephropathy. Results: Individuals who are HBsAg (+) have a slightly increased risk of developing eGFR < 60 ml/min/1.73m2 or proteinuria compared to HBsAg (-) individuals. Conclusion: The study emphasizes the substantial impact of HBV on chronic kidney disease, independent of viral replication or inflammation. The findings underscore the importance of understanding the epidemiology and clinical implications of HBV infection in the context of renal complications, revealing potential immunological and pathological mechanisms. Further studies are recommended to elucidate the complex relationship between HBV infection and kidney impairment.

The Effectiveness Of Aescin Diethylamine Salicylate In Alleviating Peri-Orbital Oedema Ollowing Septorhinoplasty: Follow-Up Study In Basrah, Iraq, Mohannad Mahdi Yaseen, Haider K. Saeed, Ansam Ghazi Abdulwahid

Iraqi National Journal of Medicine

Background: Periorbital oedema following septorhinoplasty is one of the major complications. Various measures have been advocated to alleviate this issue, including the use of a variety of chemical and/or physical materials, such as Aescin. Aim: This study aims to evaluate the role of Aescin in reducing peri-orbital oedema following septorhinoplasty. Methods: Fifty-four patients underwent primary septorhinoplasty at both Syaab and Saddar Teaching Hospitals in Basrah, Iraq, from September 2023 to September 2024. This randomized prospective interventional study collected data from patients using a designed form during the initial interview. The study population was divided into two groups randomly, group A …

Coblation Tonsillectomy: A Review Of Five-Year Experience In Basrah, Mueen Al-Abdullah, Amjed Haider Ali

Iraqi National Journal of Medicine

Background: Tonsillectomy is a very common surgery in children and it is the most routinely performed surgical operation worldwide. It is indicated for recurrent tonsillitis, chronic tonsillitis, peritonsillar abscess, suspicion of malignant diseases, and tonsillar hypertrophy causing obstructive sleep apnea. Various techniques can be employed for tonsillectomy, including cold dissection, electrocautery, bipolar diathermy dissection, radiofrequency, coblation, laser, and harmonic scalpel. Coblation is one of the most recent techniques used for tonsillectomy, which can ablate tissue by generating a field of ionized sodium molecules using a bipolar radiofrequency energy, which ablates and coagulates soft tissue into an ionized plasma layer, creating …

Serum Iron Profile In Sudanese Patients Infected By Helicobacter Pylori, Rimaz Gurashi, Abuagla M. Dafalla, Suhair A. Ahmed, Shereen Faisal, Abdelkarim A. Abdrabo

Iraqi National Journal of Medicine

Background: Helicobacter pylori is a Gram-negative, spiral-shaped, motile bacterium that represents one of the most widespread chronic infections in humans, affecting nearly half of the global population. Iron is a vital micronutrient required for almost all living organisms, including H. pylori, which relies on iron to establish colonization. Although several studies have indicated an association between iron deficiency (ID) or iron deficiency anemia (IDA) and H. pylori infection, the precise mechanisms remain incompletely understood. Aim: To assess the serum iron profile among Sudanese patients with H. pylori infection. Methods: Analytical case‑control hospital-based study was conducted at Bahri Hospital, Khartoum state …

Measles Outbreak In Anbar Province During 2023-2024. Demographic Distribution And Vaccination Status, Rafi Alani, Mohammed Dawood

Iraqi National Journal of Medicine

Background: This is the first public study covering all cities in Anbar Province regarding the measles outbreaks occurred in 2023 and 2024. Aim: To estimate the demographic distribution of measles among infected children (age, gender, residence) in Anbar Province and to study the effectiveness of the measles vaccine for each patient on infection. Methods: A retrospective analytic cross-sectional study was conducted across all sectors of Anbar Province. The patients included those who were admitted, diagnosed, and treated in various hospitals during the measles outbreak in 2023, and 2024 years. The data was recorded in files of the Anbar Public Health …