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Die Bayerischen Und Österreichischen Dialekte, Lucas Géczi Feb 2026

Die Bayerischen Und Österreichischen Dialekte, Lucas Géczi

COD in Lingua

This presentation explores the Bavarian and Austrian dialects of German, focusing on their unique sounds, vocabulary, and grammar. It highlights regional differences, the historical and cultural influences that shaped them, and their role in preserving local identity. The talk also considers how these dialects interact with Standard German in daily life and media.


Atlantischer Papageitaucher (Fratercula Arctica), Natalie Derewjanko Feb 2026

Atlantischer Papageitaucher (Fratercula Arctica), Natalie Derewjanko

COD in Lingua

The Atlantic Puffin (Fratercula arctica) is a North Atlantic seabird known for its black-and-white plumage and bright orange bill. It breeds on coastal cliffs and islands, feeding chicks by diving for fish. Although still numerous, populations are declining due to climate change, overfishing, pollution, and predators. Conservation efforts like Audubon’s “Project Puffin” have successfully restored colonies, highlighting the importance of protecting nesting sites and food sources.


Körperliche Und Psychische Aspekte Der Menstruation, Sarah Grossman Feb 2026

Körperliche Und Psychische Aspekte Der Menstruation, Sarah Grossman

COD in Lingua

This text provides an overview of menstruation, its physiological processes, and its physical and psychological effects. It explains the menstrual cycle, including the follicular and luteal phases, hormone regulation, and ovulation. Common symptoms such as cramps, fatigue, mood swings, and breast tenderness are discussed, as well as the importance of understanding hormonal changes. The text also highlights social issues, including unequal access to menstrual products, and emphasizes the significance of education and awareness for managing menstruation and promoting health.


Ein Gedicht, Maura Macdonald Feb 2026

Ein Gedicht, Maura Macdonald

COD in Lingua

This poem reflects on uncertainty, pain, and hope, exploring the tension between fleeting moments of doubt and the comforting presence of love. The speaker contemplates the passage of days and nights, the weight of sorrow, and the small joys of nature, ultimately finding solace in connection with a loved one. Themes of impermanence, emotional struggle, and the search for meaning are central, capturing a contemplative reflection on time, loss, and intimacy.


The Envoy, Evan Morter Feb 2026

The Envoy, Evan Morter

Night Flight: Online Literary Journal

This creative nonfiction piece explores the development of Envoy Mobile Jiu-Jitsu through a braided narrative that connects the author’s personal philosophy with the travels and teaching of a jiu-jitsu instructor named Ben. Opening with a vignette set in Tanzania, the essay examines how Ben's humility, adaptability, and dedication reflect the core values the author associates with an “Envoy”: Order, Fellowship, Diligence, Flexibility, and Prudence. As the narrative alternates between reflection and storytelling, it illustrates how culture, community, and personal character shape meaningful martial arts practice. The piece culminates in the author’s first in-person meeting with Ben, symbolizing the convergence of …


Catching The Stars, Vasileios Apatsidis Feb 2026

Catching The Stars, Vasileios Apatsidis

Night Flight: Online Literary Journal

No abstract provided.


Tuktuit: Caribou, William L. Blizek, Monica Blizek Feb 2026

Tuktuit: Caribou, William L. Blizek, Monica Blizek

Journal of Religion & Film

This is a review of the short film, Tuktuit: Caribou (2026), directed by Lindsay Aksarniq McIntyre.


Taga, William L. Blizek, Monica Blizek Feb 2026

Taga, William L. Blizek, Monica Blizek

Journal of Religion & Film

This is a review of the short film, Taga (2026), directed by Jill Marie Sachs.


Together Forever, William L. Blizek, Monica Blizek Feb 2026

Together Forever, William L. Blizek, Monica Blizek

Journal of Religion & Film

This is a review of the short film, Together Forever (2026), directed by Gregory Barnes.


Dr. Mabel Andrews Biography Feb 2026

Dr. Mabel Andrews Biography

Dr. Mabel Andrews Collection

A short biography of Dr. Mabel Elizabeth Andrews written by her family. Included in the document are a few obituaries posted in various sources.


The Passenger In 12a, Cristopher G. Cando Feb 2026

The Passenger In 12a, Cristopher G. Cando

Night Flight: Online Literary Journal

This short story follows Mateo Alvarez, a TSA officer whose life has settled into a rigid routine, and Elena, a passenger beginning a new chapter in her life. Their brief interaction during a routine security screening becomes a quiet but meaningful exchange, which centers on kindness, memory, and the courage to move forward. As Elena carries her father's journal with her on a flight toward a new opportunity, Mateo is reflecting on the choices he has avoided and the life he has placed on pause. Through parallel perspectives, this story explores themes of transition, human connection, and the impact of …


Effects Of Bungee-Based Training On Physical Performance And Arch Jump Kinematics In Female College Rhythmic Gymnasts, Nasser Abouzeid, Mariola Gepfert, Abdulrahman I. Alaqil, Abdulmalek K. Bursais, Hussein Hashoos, Mohammed S. Alibrahim, Labeeb Z. Moseekh, Amr S. Hamza Feb 2026

Effects Of Bungee-Based Training On Physical Performance And Arch Jump Kinematics In Female College Rhythmic Gymnasts, Nasser Abouzeid, Mariola Gepfert, Abdulrahman I. Alaqil, Abdulmalek K. Bursais, Hussein Hashoos, Mohammed S. Alibrahim, Labeeb Z. Moseekh, Amr S. Hamza

Baltic Journal of Health and Physical Activity

Background: The purpose of this study was to examine the effects of an eight-week bungee-based training program on selected physical performance variables and arch jump kinematics in female college rhythmic gymnasts. Material and methods: Eighteen female college students (age: 18.1 ± 0.9 years) were randomly assigned to an experimental group (EG; n = 9) or a control group (CG; n = 9). The EG completed a bungee workout training program three times per week for eight weeks, while the CG followed a traditional rhythmic gymnastics training program. Physical performance variables included vertical jump, leg strength, back strength, standing long jump, …


Advances In 2025: The Year In Review, Richard Alweis, Elizabeth Mamo, Christina Goodermote Feb 2026

Advances In 2025: The Year In Review, Richard Alweis, Elizabeth Mamo, Christina Goodermote

Advances in Clinical Medical Research and Healthcare Delivery

No abstract provided.


Obesity As A Health Priority: Insights From Research Productivity In The Arab World, Rania Hammami, Mirvat Alsnag Feb 2026

Obesity As A Health Priority: Insights From Research Productivity In The Arab World, Rania Hammami, Mirvat Alsnag

Saudi Medical Journal

No abstract provided.


National Heart Center/Saudi Heart Association 2025 Guidelines For Cardiovascular Diseases Prevention And Risk Assessment, Jamilah S Alrahimi, Shukri M. Al Saif, Laith Hussain-Alkhateeb, Ali M. Albarrati, Owayed M. Alshammeri, Talal S. Alghamdi, Khalid A. Al Faraidy, Ada M Al-Qunaibet, Nada A. Alnaji, Rasha A. Alfawaz, Waleed M. Alharbi, Waleed A. Alhabeeb, Fahad M. Alnouri, Adel A. Tash Feb 2026

National Heart Center/Saudi Heart Association 2025 Guidelines For Cardiovascular Diseases Prevention And Risk Assessment, Jamilah S Alrahimi, Shukri M. Al Saif, Laith Hussain-Alkhateeb, Ali M. Albarrati, Owayed M. Alshammeri, Talal S. Alghamdi, Khalid A. Al Faraidy, Ada M Al-Qunaibet, Nada A. Alnaji, Rasha A. Alfawaz, Waleed M. Alharbi, Waleed A. Alhabeeb, Fahad M. Alnouri, Adel A. Tash

Saudi Medical Journal

Objectives: To develop an evidence-based clinical guideline for the prevention and management of cardiovascular diseases (CVDs) in Saudi Arabia, tailored to local epidemiology and healthcare needs.

Methods: A multidisciplinary task force comprising cardiologists, public health specialists, and epidemiologists from different healthcare sectors in Saudi Arabia developed the guideline. Evidence synthesis was based on a comprehensive literature review and adaptation of international guidelines, particularly the 2021 European Society of Cardiology recommendations, contextualized to the Saudi setting.

Results: The guideline provides recommendations for both primary and secondary CVD prevention. Primary prevention emphasizes risk assessment incorporating genetic, lifestyle, and clinical factors, as well …


From Text To Test: Pre-Lecture Reading Boosts Medical Students’ Comprehension And Retention, Hamad A. Alfahaad, Mohammed Y. Alasmary, Emad M. Masuadi, Mohi Eldin M. Magzoub, Henk G. Schmidt Feb 2026

From Text To Test: Pre-Lecture Reading Boosts Medical Students’ Comprehension And Retention, Hamad A. Alfahaad, Mohammed Y. Alasmary, Emad M. Masuadi, Mohi Eldin M. Magzoub, Henk G. Schmidt

Saudi Medical Journal

Objective: Medical students frequently attend lectures without prior review of the related literature when preparing for examinations. It raises the question of whether studying the material in advance could enhance their learning outcomes during lectures.

Methods: A total of 102 medical students from a Saudi Arabian university took part in this research. Participants were assigned to one of 2 cohorts: one read a 4-page passage before a 15-minute lecture, while the other attended the lecture before reading the passage. Knowledge acquisition was measured using a test that assessed their ability to recall concepts administered 3 times—prior to the session, post …


Medication Errors Reporting And Analysis: A Comparative Study For Advancing Medication Safety Practices In Ministry Of Health Hospitals In Saudi Arabia, Saleh A. Alghamdi Feb 2026

Medication Errors Reporting And Analysis: A Comparative Study For Advancing Medication Safety Practices In Ministry Of Health Hospitals In Saudi Arabia, Saleh A. Alghamdi

Saudi Medical Journal

Objectives: To analyze and compare these stages, types, frequency, causes, and corrective actions related to medication errors (MEs) reported in Ministry of Health (MOH) hospitals in Saudi Arabia, and thereby enhance medication safety through data driven decisions.

Methods: A retrospective cross-sectional study was conducted using ME reports submitted to the Saudi MOH national reporting system from January 2023 to December 2024.Data were collected from nine hospitals, covering medication involved, reporting personnel, level of harm and corrective actions. A novel stratification framework (NSF) was used to visualize emerging risks and protective trends. Statistical analyses were conducted using relative risk (RR), risk …


Research Productivity On Obesity In The Arab World: A Bibliometric Analysis (2004–2023), Jamil Adnan Samkari, Ahamd Azam Malik Feb 2026

Research Productivity On Obesity In The Arab World: A Bibliometric Analysis (2004–2023), Jamil Adnan Samkari, Ahamd Azam Malik

Saudi Medical Journal

Objective: To examine obesity research trends in Arab countries to inform policies and interventions.

Methods: A bibliometric analysis was conducted using the Web of Science database accessed via King Abdulaziz University’s electronic library. Publications on obesity research in Arab countries from 2004 to 2023 were analyzed using R-Bibliometrix. Key parameters included publication volume, leading authors and institutions, funding sources, keyword co-occurrence networks, and collaboration patterns.

Results: Obesity-related research output in Arab countries demonstrated consistent growth from 2004 to 2023, with a threefold increase in publications since 2015. Regional and international collaborations have intensified, although disparities in research productivity persist across …


Endovascular Thrombectomy For Acute Ischemic Stroke Among Stroke Patients In Jeddah, Saudi Arabia. A Retrospective Cohort Study (2024) Detailing Dual Center Experience, Abdullah M Alkutbi, Omar Abdulhamidayoub, Fawaz Mosaedalshareef, Mohammed M Alwadi, Rawan I Alqurashi, Rayan I Almaghrabi, Naif F Alharbi, Omar M Alhazmi, Ziad H Alzabidi, Nagham S Alsolaimani, Saher F Alqarni Feb 2026

Endovascular Thrombectomy For Acute Ischemic Stroke Among Stroke Patients In Jeddah, Saudi Arabia. A Retrospective Cohort Study (2024) Detailing Dual Center Experience, Abdullah M Alkutbi, Omar Abdulhamidayoub, Fawaz Mosaedalshareef, Mohammed M Alwadi, Rawan I Alqurashi, Rayan I Almaghrabi, Naif F Alharbi, Omar M Alhazmi, Ziad H Alzabidi, Nagham S Alsolaimani, Saher F Alqarni

Saudi Medical Journal

Background: Te evaluate the outcomes of Endovascular thrombectomy (EVT) -treated AIS patients in Jeddah, Saudi Arabia, and explores predictors of functional recovery. Endovascular thrombectomy (EVT) is the standard of care for acute ischemic stroke (AIS), though patient outcomes can vary based on regional and clinical factors.

Method: A retrospective cohort study was conducted using medical records from King Abdulaziz University Hospital (KAUH) and King Fahad Hospital Jeddah (KFHJ), including AIS patients treated with EVT between January 2020 and July 2024. Neurological status was assessed using the NIH Stroke Scale (NIHSS), and clinical outcomes were evaluated with the modified Rankin Scale …


Influence Of Metabolic Dysfunction-Associated Steatotic Liver Disease On Pattern And Management Of Acute Coronary Syndrome, Elshazly Abdulkhalik, Nagat Ibrahim, Selim Sidhom, Hesham H Alqurashi, Khaled Alghashmari, Muhammad Alotaibi, Ahmed Alqurashi, Moath Alzahrani, Shahad Alqahtani, Abdulaziz Alshalan, Nouran Althumali, Mazen Aljohani, Saud Alzahrani, Haidi Karam-Allah Ramadan Feb 2026

Influence Of Metabolic Dysfunction-Associated Steatotic Liver Disease On Pattern And Management Of Acute Coronary Syndrome, Elshazly Abdulkhalik, Nagat Ibrahim, Selim Sidhom, Hesham H Alqurashi, Khaled Alghashmari, Muhammad Alotaibi, Ahmed Alqurashi, Moath Alzahrani, Shahad Alqahtani, Abdulaziz Alshalan, Nouran Althumali, Mazen Aljohani, Saud Alzahrani, Haidi Karam-Allah Ramadan

Saudi Medical Journal

Objectives: To determine the influence of metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and hepatic fibrosis on the pattern and management of patients who had acute coronary syndrome (ACS).

Methods: Retrospective records of patients with ACS included demographic, electrocardiographic, and laboratory data of platelets count, glycated hemoglobin, lipogram, liver and cardiac enzymes. Ultrasound was used to evaluate fatty liver. Coronary angiography data included the number, site and percentage of the coronary arteries occluded. The type and outcome of treatment of ACS were recorded. Laboratory markers were measured to evaluate fibrosis.

Results: The study recruited 259 patients, and the majority were males. …


Juvenile Idiopathic Arthritis Registry At King Abdullah Specialized Children’S Hospital (Jiar-Kasch) In Riyadh, Saudi Arabia, Jubran T. Alqanatish, Abdullah I. Almojali, Wejdan M. Algbaiwi, Abdullah S. Alqahtani, Abdulrahman A. Alrasheed, Lubna A. Alnasser, Wafaa M. Alsuwairi Feb 2026

Juvenile Idiopathic Arthritis Registry At King Abdullah Specialized Children’S Hospital (Jiar-Kasch) In Riyadh, Saudi Arabia, Jubran T. Alqanatish, Abdullah I. Almojali, Wejdan M. Algbaiwi, Abdullah S. Alqahtani, Abdulrahman A. Alrasheed, Lubna A. Alnasser, Wafaa M. Alsuwairi

Saudi Medical Journal

Objectives: To establish and maintain a comprehensive, up-to-date registry of juvenile idiopathic arthritis (JIA) cases, and to outline the methodology used in creating it.

Methods: Retrospective and prospective data collection commenced in August 2021, using the Hospital Information System to identify electronic medical records of JIA patients. All individuals diagnosed with JIA and receiving follow-up care at King Abdullah Specialized Children’s Hospital (KASCH) in Riyadh were included. A broad range of variables covering sociodemographic characteristics, clinical features, laboratory results, imaging findings, and therapeutic medications were recorded in the REDCap platform. Data collection update occurs every 6 months.

Results: By December …


Clinical Characteristics And Outcomes Of Patients With Amphetamine Associated Emergency Department Visits At A Tertiary Care Hospital In Riyadh, Saudi Arabia, Mohammed K. Alsharef, Mahdi Almutairi, Nouf Ababtain, Mohammed Alajmi, Abdulrahman Alrajhi, Faisal Alhusain, Mohammad Al Deeb Feb 2026

Clinical Characteristics And Outcomes Of Patients With Amphetamine Associated Emergency Department Visits At A Tertiary Care Hospital In Riyadh, Saudi Arabia, Mohammed K. Alsharef, Mahdi Almutairi, Nouf Ababtain, Mohammed Alajmi, Abdulrahman Alrajhi, Faisal Alhusain, Mohammad Al Deeb

Saudi Medical Journal

Objective: To investigate the demographic and clinical profiles of patients presenting with amphetamine-related emergencies at a tertiary hospital in Riyadh, Saudi Arabia. Amphetamine use is an escalating public health issue linked to a rise in emergency department (ED) visits.

Methods: This retrospective study encompasses 14 years and focuses on individuals diagnosed with amphetamine-related toxicity.

Results: Among the 659 cases studied, a predominant 96% were male, with over half (52%) aged between 19 and 30 years. Most patients (91%) were Saudi nationals. The leading cause of presentation was trauma, accounting for 24% of cases. This was followed by altered mental status …


Targeted Neonatal Echocardiography And Neonatal Hemodynamics In The Kingdom Of Saudi Arabia: A One-Year Experience In Service Implementation, Abdulaziz Homedi, Kamal Ali Ali, Abdulrahman Almehaid, Mohanned Alrahili, Abdulrahman Mandurah, Mohammed Almahdi, Faisal Alamer, Eman Bazbouz, Shatha Algarni, Atheer Alshehri, Faisal Alsehli, Hanof Bakri Feb 2026

Targeted Neonatal Echocardiography And Neonatal Hemodynamics In The Kingdom Of Saudi Arabia: A One-Year Experience In Service Implementation, Abdulaziz Homedi, Kamal Ali Ali, Abdulrahman Almehaid, Mohanned Alrahili, Abdulrahman Mandurah, Mohammed Almahdi, Faisal Alamer, Eman Bazbouz, Shatha Algarni, Atheer Alshehri, Faisal Alsehli, Hanof Bakri

Saudi Medical Journal

Objective: To evaluate the impact of a newly established targeted neonatal echocardiography (TNE) and Neonatal Hemodynamics consultation service on the assessment and management of neonates.

Methods: This is a descriptive retrospective cohort study that included all neonates who underwent TNE consultations in the Neonatal Intensive Care Unit from October 2023 and September 2024. Clinical indications, diagnostic findings, and subsequent management were analyzed.

Results: A total of 237 TNE consultations were performed for 105 neonates. The mean gestational age was 29.9 weeks, and the mean birth weight was 1433 grams. On average, 19.8 echocardiographic scans were performed per month. The leading …


Gender Differences In Sociodemographic And Clinical Characteristics Of Methamphetamine Use In Saudi Arabia, Halima M. Adam, Mohamed Abouzed, Ahmed H. Aljadani, Benayan B. Alrasheedy, Muath A. Alarfaj, Salwa R. Alshammari, Mohamed S. Almuqahwi Feb 2026

Gender Differences In Sociodemographic And Clinical Characteristics Of Methamphetamine Use In Saudi Arabia, Halima M. Adam, Mohamed Abouzed, Ahmed H. Aljadani, Benayan B. Alrasheedy, Muath A. Alarfaj, Salwa R. Alshammari, Mohamed S. Almuqahwi

Saudi Medical Journal

Objectives: To explore gender-related variations in sociodemographic factors, clinical presentations, and psychosocial characteristics among methamphetamine users in Saudi Arabia.

Methods: A retrospective cross-sectional study was conducted using the electronic health records of 1,181 patients (91% male, 9% female) treated at multiple Erada Mental and Addiction Centers across Saudi Arabia (2020–2024). Data on sociodemographic characteristics, methamphetamine use patterns, psychiatric comorbidities, and psychosocial functioning were collected and analyzed using validated tools, including the Addiction Severity Index, Beck Depression and Anxiety Inventory, and Quality of Life Scale.

Results: Female participants were younger than males (mean age 25.3 vs 28.5 years; p < 0.001) and initiated methamphetamine at a later age (21.4 vs 19.2 years; p < 0.001). Females had greater proportion of daily use (65.4% vs. 60%, p …


Invasive Methicillin-Susceptible And Methicillin-Resistant Staphylococcus Aureus Infections In The Pediatric Population: Prevalence And Management Outcomes, Khalifa M. Binkhamis, Ibrahim A. Alhezam, Hassan A. Alabdullatif, Othman M. Alabdullah, Omar Y. Alkadhi, Nawaf M. Alrefaei, Abdullah S. Almayah, Fatema A. Juma, Sarah S. Alangari Feb 2026

Invasive Methicillin-Susceptible And Methicillin-Resistant Staphylococcus Aureus Infections In The Pediatric Population: Prevalence And Management Outcomes, Khalifa M. Binkhamis, Ibrahim A. Alhezam, Hassan A. Alabdullatif, Othman M. Alabdullah, Omar Y. Alkadhi, Nawaf M. Alrefaei, Abdullah S. Almayah, Fatema A. Juma, Sarah S. Alangari

Saudi Medical Journal

Objectives: Infections by invasive methicillin-resistant Staphylococcus aureus (MRSA) are associated with higher morbidity and mortality compared to methicillin-susceptible Staphylococcus aureus (MSSA) infections, and have increased significantly in both healthy children and children with chronic illnesses. In our study we aimed to estimate the prevalence of invasive MSSA and MRSA among invasive Staphylococcus aureus (S. aureus) infections in the pediatric population and measure the association between management outcomes and methicillin resistance in these infections.

Methods: We conducted an observational, analytical, retrospective cross-sectional, chart-review study of pediatric patients (aged ≤16 years) admitted to King Khalid University Hospital in Riyadh, Saudi Arabia …


Prevalence Of Autoimmune Thyroid Disease Among Individuals With Celiac Disease In A Primary Care Setting In Riyadh, Saudi Arabia, Mansour I. Alrasheed, Hussam Jnaid, Faisal K. Alrasheed, Tarfah R. Alsharidi, Abdulelah I. Alrasheed, Sarah A. Alobaid, Norah A. Sulaiman Feb 2026

Prevalence Of Autoimmune Thyroid Disease Among Individuals With Celiac Disease In A Primary Care Setting In Riyadh, Saudi Arabia, Mansour I. Alrasheed, Hussam Jnaid, Faisal K. Alrasheed, Tarfah R. Alsharidi, Abdulelah I. Alrasheed, Sarah A. Alobaid, Norah A. Sulaiman

Saudi Medical Journal

Objectives: Celiac disease (CD) is a prevalent autoimmune disorder triggered by gluten consumption, leading to an immune response that damages the small intestine. Research shows a link between CD and autoimmune thyroid disorders (AITD). This study seeks to determine the prevalence of AITD among adult and pediatric patients with CD in the primary care setting in Riyadh, Saudi Arabia.

Methods: A retrospective cross-sectional study reviewed electronic health records of individuals diagnosed with CD from January 2016 to December 2023 at King Faisal Specialist Hospital and Research Centre. Collected data encompassed patient demographics, diagnostic approaches, thyroid function assessments, thyroid autoantibody profiles, …


Magnitude Of Abdominal Solid Organs Injuries Among Patients With Pelvic Fracture At King Abdullah Hospital, Bisha City, Saudi Arabia, Ali Ibrahim Alshehri, Mohammed Jalawi Karkaman, Nawaf Amer Alsoiry, Naif Abdulaziz Alqarni Feb 2026

Magnitude Of Abdominal Solid Organs Injuries Among Patients With Pelvic Fracture At King Abdullah Hospital, Bisha City, Saudi Arabia, Ali Ibrahim Alshehri, Mohammed Jalawi Karkaman, Nawaf Amer Alsoiry, Naif Abdulaziz Alqarni

Saudi Medical Journal

Objective: To access the magnitude of these injuries in patients with pelvic fractures at King Abdullah Hospital, Bisha, Saudi Arabia. Abdominal solid organ injuries are life-threatening and results in adverse health effects particularly to patients with pelvic fracture.

Methods: An analytical cross-sectional retrospective hospital-based study that reviewed a total of 236 medical records of patients with abdominal organ injuries and pelvic fractures at King Abdullah Hospital, Bisha, Saudi Arabia. Cleaned data was coded and analyzed with the use of SPSS version 23 to drive key insights.

Results: The study comprised of 236 patients in total. Approximately 38 (16.1%) patients had …


Sphingosine-1-Phosphate Regulation To Alleviate Sickle Cell Disease Severity: A Promising Therapeutic Approach, Shahanas Chathoth Feb 2026

Sphingosine-1-Phosphate Regulation To Alleviate Sickle Cell Disease Severity: A Promising Therapeutic Approach, Shahanas Chathoth

Saudi Medical Journal

Sickle cell disease (SCD) is a genetic disorder that affects millions of individuals worldwide. Chronic anemia, hemolysis and vasculopathy are the most common symptoms that arise from hemoglobin (Hb) polymerization, which is the primary event of SCD. The above process can lead to erythrocyte sickling. Therapeutic options for SCD remain limited, and novel therapies are still being evaluated for their effectiveness in particular populations. Sphingosine-1-phosphate (S1P), a significant bioactive sphingolipid, acts as a potent signal mediator, modulating several cellular functions. The potential role of erythrocyte-S1P in enhancing SCD severity has been previously reported by multiple studies. Therefore, the present review …


Colorectal Cancer Screening In Saudi Arabia: Current Challenges And Future Directions, Abdulrahman A. Aljabri, Abdulrahman G. Alharbi Feb 2026

Colorectal Cancer Screening In Saudi Arabia: Current Challenges And Future Directions, Abdulrahman A. Aljabri, Abdulrahman G. Alharbi

Saudi Medical Journal

Colorectal cancer has become a major public health concern in Saudi Arabia. It is the most prevalent cancer among men and the third most prevalent among women. Although screening for people aged 45-75 is recommended by national recommendations, screening uptake is still below 10%, and less than 1% of older persons have a colonoscopy. With regional differences that vary from age-standardized rates of 3.2 per 100,000 in Jouf to 21.8 per 100,000 in Riyadh among men, approximately 29% of cases are detected at late stages. Therefore, we assessed the epidemiological, social, and health-related systemic structures preventing effective colorectal cancer screening …


Prevalence Of Carbapenem-Resistant Enterobacteriaceae In Intensive Care Units In Saudi Arabia: A 10-Year Systematic Review, Shadi A. Zakai Feb 2026

Prevalence Of Carbapenem-Resistant Enterobacteriaceae In Intensive Care Units In Saudi Arabia: A 10-Year Systematic Review, Shadi A. Zakai

Saudi Medical Journal

Objective: To synthesize research on the prevalence and distribution patterns of carbapenem-resistant Enterobacteriaceae (CRE) in Intensive Care Units (ICUs) across Saudi Arabia. It also seeks to evaluate molecular resistance profiles, identify associated risk factors, assess antimicrobial susceptibility, and examine infection control strategies within these critical care settings.

Methods: A systematic analysis was conducted, including cross-sectional, retrospective, and genomic studies from various tertiary hospitals in Saudi Arabia. The review focused on epidemiological trends, molecular characterization of CRE strains, clinical correlates, and the outcomes of implemented intervention strategies.

Results: The findings indicate a high and steadily increasing prevalence of CRE, often exceeding …