Digital Commons Network^™

Contempt Of Court Dalam Proses Peradilan Di Indonesia, Prof Padmo Wahjono, S.H.

Jurnal Hukum & Pembangunan

Abstract

Pranata-Pranata Hukum Yang Baru Dan Tinjauan Terhadap Undang-Un Dang Rumah Susun, Yacob Mohs;N, S.H.

Jurnal Hukum & Pembangunan

Abstract

Peranan Notaris Dalam Pembangunan Hukum, Soetomo Ramelan, S.H.

Jurnal Hukum & Pembangunan

Abstract

Realitas Hak-Hak Untuk Mendapat Kan Informasi Dan Berkomunikasi Di Indonesia, T. Mulya Lub;S, S.H. , Llm

Jurnal Hukum & Pembangunan

Abstract

“Blue Rings” In Engelmann Spruce From The Greater Yellowstone Ecoregion: Their Presentation And Efficacy As Proxies For Ephemeral Cooling Events, Isaac Grimm, Maegen Rochner

The Cardinal Edge

As the polar jet stream’s activity transforms under climate change’s influence, short-term, or ephemeral, cooling events could become more frequent. Understanding how such cooling events may affect forest dynamics and tree-growth can allow us to predict how the morphing jet stream may reflect in our future forests. “Blue rings” (BRs) have presented themselves as subsections of annual rings, made clear through the double-staining of microsections of wood, which have been associated with the interruption of conifers’ lignification process. Such features could allow us to peer back into pre-instrumental records and assess how a tree’s growth and their surrounding canopy may …

Nursing Interventions To Reduce Anxiety And Psychological Distress In Breast Cancer Patients In The Us, Alexis Abboud, Al Araydeh Mifleh

The Cardinal Edge

Background Breast cancer patients frequently experience psychological challenges, such as anxiety, distress, and diminished quality of life (QoL). Nursing interventions show promise in addressing these issues; however, a comprehensive synthesis of their impact is lacking. This review evaluates the effectiveness of nursing interventions in reducing anxiety and psychological distress while improving QoL.

Research Question What nursing interventions effectively reduce anxiety and psychological distress and improve QoL among breast cancer patients in the United States?

Methods A systematic review was conducted following PRISMA 2020 guidelines. Searches of CINAHL, APA PsycInfo, and Medline identified studies published in the last five years in …

Settler Colonialism: A Case-Study Analysis Of Dam Infrastructure In The American West, Kassidy Haynes, Carrie Mott

The Cardinal Edge

In 17^th-century North America, a number of world powers began extensive colonial efforts to stake a claim on territories and their resources. Settler colonialism in the United States followed a distinct track to the west compared to that which occurred in the east following this initial land-grab. Because infrastructure preceded some formal, highly concentrated settlement in the western United States, this region experienced the oppression of settler colonialism in distinct manifestations. Namely, the physical imposition of construction projects such as dams established early dynamics of differential power and control between the federal government and the diverse array of …

Evolving Solutions For Red Blood Cell Preservation, Ali Alkafaji, Charles A. Elder, Mohammad Zaidi, Kavin Parthiv, Michael A. Menze

The Cardinal Edge

In emergencies such as natural disasters, armed conflicts, or during outer space missions, the availability of transfusable blood can mean the difference between life and death. Red blood cells (RBCs) must be stored at +4 ± 2 °C and have a shelf life of just 42 days, which makes maintaining a stable blood supply during adverse conditions extraordinarily challenging. This challenge was especially apparent during the COVID-19 pandemic when hospitals faced severe blood shortages. Freeze-drying, or lyophilization, offers a promising avenue to extend the shelf life of RBCs for transfusion during crises. However, a significant hurdle in dry preservation is …

Filifactor Alocis Disrupts Efferocytosis To Sustain Inflammation In Periodontitis, Ella Dye, Silvia Uriarte, Ruth Idowu

The Cardinal Edge

Background: Filifactor alocis is a Gram-positive, obligate anaerobe that has emerged as a diagnostic marker of periodontitis. Neutrophils and macrophages are key players in oral immune homeostasis. Neutrophils are short-lived cells and constitutively undergo apoptosis. This apoptotic program can be accelerated or delayed by bacterial interactions. Macrophages clear apoptotic neutrophils via “efferocytosis,” a crucial mechanism for resolving inflammation and preventing tissue damage. The efferocytic process downregulates the expression and release of proinflammatory cytokines such as interleukin (IL)-6 and IL-23 while promoting anti-inflammatory responses. Our previous findings demonstrated that F. alocis delays neutrophil apoptosis, with fewer apoptotic cells observed after 18 …

Galaxy Zoo: A Catalog Of ~1000 Occulting Pairs In The Desi Legacy Survey For Dust Studies, Trevor A. Butrum, Benne Holwerda

The Cardinal Edge

Occulting pairs of galaxies, where a foreground galaxy partially overlaps a background galaxy, are becoming increasingly valuable for studying dust attenuation and other dust properties in galaxies. These occulting systems present a unique opportunity to derive attenuation measurements by modelling the light from both galaxies and inferring the missing light in the overlapping regions, leaving only the light attenuated by dust remaining. However, the current master catalogue of these pairs is still relatively limited in number, and expanding such a catalogue will provide significant advantages. To achieve this, we use galaxies classified as "overlapping" from Galaxy Zoo DECaLS (GZD-1, 2, …

How Medical Students Use Comforting Language When Taking A Sexual History For Different Presenting Complaints, Abigail Breeze, Emily J. Noonan, Laura Weingartner

The Cardinal Edge

No abstract provided.

Patient Presentation Affects Medical Student Comfort During Sexual Health Encounters, Harshith Jella, Emily J. Noonan, Laura Weingartner

The Cardinal Edge

BACKGROUND

Previous research has identified some disparities between the care that masculine- and feminine-presenting patients experience with regards to sexual health. These disparities could cause feelings of unease and also difficulty with patient-physician communication. In medical education, standardized patients can help students identify and address implicit biases that could propagate as providers.

METHODS

The study population consisted of second year medical students (n=100) from the University of Louisville who completed sexual history-taking during a standardized patient encounter. Coders evaluated the phrases used, perceived comfort levels, and SP feedback among masculine- and feminine-presenting standardized patients.

RESULTS

While the patient presentation did …

Activation Of Autophagy In Human Neutrophils In Response To Emerging Oral Pathogen Peptoanaerobacter Stomatis, Mya Philipose, Shikha Srivastava, Silvia Uriarte

The Cardinal Edge

Background: Periodontitis is a chronic, inflammatory disease that affects over 50% of the global population and is a leading cause of tooth loss. It is associated with the accumulation of oral pathogens that thrive in inflamed environments and contribute to the destruction of gum tissue and underlying bone. Neutrophils, the most abundant immune cells in the oral cavity, serve as the first line of defense against these pathogens. However, some bacteria can alter neutrophil responses to promote their survival, leading to sustained inflammation and tissue damage. This study focuses on Peptoanaerobacter stomatis, a Gram-positive anaerobic bacterium that is highly …

Egf Enhances Re-Epithelization In Our Ex-Vivo Pig Eye Model, Andrew D. Le, Lisandra Plana-Ramos, Kate Tarvestad, Brian Ceresa

The Cardinal Edge

The cornea, the foremost anterior portion of the eye, plays a critical role in vision by refracting light and serving as a protective barrier. Its three distinct layers—the outermost epithelial layer, the thick stromal layer, and the innermost endothelial layer work together to maintain corneal transparency and function. The epithelial layer is particularly susceptible to damage, which can compromise the eye’s defense against foreign particles such as bacteria and viruses, potentially leading to infection and blindness. In this study, we established an ex vivo porcine corneal model to quantitatively and qualitatively investigate corneal re-epithelialization. Using adult pig eyes sourced from …

Exploring The Impact Of Perceived Patient Age And Gender On Medical Students' Comfort And Confidence With Sexual History-Taking, Haven Gabrielle V. Romero, Laura Weingartner

The Cardinal Edge

BACKGROUND

Many medical students lack confidence when navigating a patient sexual history. Discomfort may stem from a lack of experience, societal taboos surrounding sexual health discussions, or concerns about maintaining professionalism while addressing sensitive topics. We aimed to investigate comfort and confidence among student genders and patient age.

METHODS

We analyzed 107 standardized patient (SP) encounters of second-year students across three sexual health cases with different presenting complaints. Perceived comfort and confidence were inferred from student body language, language, and conversational tone, which were categorized as: comfortable/confident, fairly comfortable/confident, not comfortable/confident.

RESULTS

Across cases, students were comfortable/confident in half (50%). …

Analyzing The Climate-Growth Response Of Hemlock Species In Tight Hollow, Daniel Boone National Forest, Kentucky, Usa, Jacob G. Brown

The Cardinal Edge

Kentucky’s (KY) local climate is facing uncertainty as the influence of climate change pushes hydrological variation to its extremes. Proxy-based data can be used to better understand this variation by analyzing past climatic conditions. Tree rings provide valuable proxy data on an annual to sub-annual resolution that can be used to create climate reconstructions. However, the state of Kentucky lacks high temporal and spatial resolution datasets for accurate climate reconstruction analysis. Climate-sensitive tree species and locations must be identified and evaluated within Kentucky to further enhance these datasets to a higher resolution. Our research objective is to analyze the climate-growth …

High Polarization In Narrow Line Seyfert 1 Galaxy Iras 1239.7+3333, Bryn Connelly, Dirk Grupe Phd

The Cardinal Edge

IRAS 1239 is a narrow line Seyfert 1 galaxy discovered with the ROSAT All-Sky survey. It is interesting because it shows very high polarization, but very little cold X-ray absorption, potentially revealing more insight into the classification of Seyfert galaxies. An Active Galactic Nucleus, or AGN, is an accreting black hole at the center of a galaxy. Galaxies containing these AGNs are known as active galaxies. There are several different types of active galaxies, including Seyfert galaxies. These are a common galaxy type, making up around 10% of galaxies. They are classified by having strong emission lines and detectable host …

The Impact Of Linguistic Discrimination On The Mental Health Of International College Students: A Systematic Review Protocol Design, Isabella G. Hausladen, Chinarah D. Winston, Maria Kondaurova, Lidiya Grote

The Cardinal Edge

The analysis of education data from the National Foundation for American Policy demonstrates that between 50% and 82% of the full-time graduate students in STEM fields at United States universities are international students who provide a wide range of expertise, knowledge, and skills needed to participate in the STEM workforce (National Foundation for American Policy, 2017). One of the challenges international college students face is self-perceived linguistic discrimination, defined as a person’s individual experience of feeling unfairly treated due to their accent, proficiency, or choice of language. The objective of this study is to develop a protocol for a systematic …

Exploring A Game Before Instruction To Improve Understanding Of Social Dilemmas, Kyisha M. Walter

The Cardinal Edge

Social dilemmas occur when groups must balance self-interest with group interests when there are limited resources. Despite their prevalence in society, understanding varies and can magnify the possible risks associated. This study examines the differences in learning about ecological and social aspects of social dilemmas for small groups when confronted with a simulated social dilemma in a lab experiment. These conditions are meant to imitate broader classroom and field setting uses. Participants (N=116) were randomly assigned to one of two conditions and played a social dilemma board game twice. In the Lesson-First condition (n=56), participants received a lesson in the …

Hsp90 Inhibitor In Reducing Integrated Stress Response In An Experimental Mouse Model Of Spinal Cord Injury, Yousef Abozaid, Aditya Sarkar, Lukasz P. Slomnicki, Michal Hetman

The Cardinal Edge

Spinal cord injury (SCI) initiates a complex cascade of molecular events, including protein misfolding and neuroinflammation, contributing to neural damage and impaired functional recovery. Heat Shock Protein 90 (HSP90), a critical molecular chaperone involved in cellular stress responses, emerges as a promising therapeutic target to mitigate secondary damage after SCI. This study was designed to validate the in-vivo effects of different doses of HSP90 inhibitor, HSP990-i, administered acutely after moderate T9 SCI mouse model. The level of HSP70 protein level is measured through western blot from the injury epicenter. Adult mice underwent experimental contusive SCI at the T9 level, followed …

Effects Of Phosphorus Addition On Fungal Colonization In Little Bluestem, Isabel M. Zanartu, Alexx Nicholas, Mckenzie Goodwyn, Connor Morozumi

The Cardinal Edge

Little Bluestem (Schizachyrium scoparium) is a North American perennial grass that is able to tolerate high heat and droughts. This is possible by its extensive underground root network that taps deep into the ground for resources. Within the same soil systems are fungal endophytes, which are symbionts that live within plant tissues including roots. Fungal endophytes can affect host growth and nutrient acquisition, but the functional role these endophytes play in plant health may be dependent on the abiotic conditions the plant is facing. In the modern era, one large driver of abiotic conditions is synthetic fertilizer use which alters …

An Integration Of Care Ethics Into Design Thinking, Ellie Bruner

The Cardinal Edge

In An Ethic of Caring, Nell Noddings establishes a humanistic ethical ideal—ethics should be based upon our natural sentiment of caring, not abstract moral law. She differentiates ethical caring from natural caring; ethical caring requires stirring past sentiments and a call to care for others that natural caring may not provoke. Noddings places the ethical ideal above the moral principle because the latter is too general; the ethical ideal applies to specific situations with the universal aim of “maintenance of the caring relation” (Noddings 702). Limits to our ethical responsibilities are relational: there must be “existence of or potential …

Light As An Environmental Toxin: Impacts Of Temporal Circadian Misalignment On Physiology, Behavior, And Lifespan In Drosophila, Aubrey Reitzel, Krish Patel, Breanna Beard, Dae-Sung Hwangbo

The Cardinal Edge

In the modern world, we are exposed to irregular light patterns, which can disturb circadian rhythms. Circadian rhythms are patterns of behavior that operate on a 24-hour cycle and are regulated by the interactions between external signals and the internal circadian clock, which regulates sleep/wake patterns, feeding and sleep behavior, and resistance to starvation. Little is known about the impact of misalignment of these circadian rhythms as related to dietary composition on the lifespan, behaviors, and physiological changes of Drosophila. We hypothesized that circadian misalignment would significantly reduce lifespan and alter behaviors and physiologies. In this study, mated female …

Impact Of Legacy Amf Communities On Vegetative Growth & Yield Of Soybean, Dylan Habeeb, Connor Morozumi, Natalie Christian

The Cardinal Edge

Soil microbial communities are increasingly recognized as an important factor in sustainable agriculture. Arbuscular mycorrhizal fungi (AMF), are key players in these communities, known to benefit their plant host in a number of ways, such as increased nutrient uptake. Plants can partner with multiple AMF species; however, little is known about how interactions between multispecies communities of AMF impact plant growth and yield. In an agricultural setting, the long-term development of these communities following practices such as rotational planting or cover cropping is also an important consideration, but there is little research on the long-term legacy of AMF communities or …

Effects Of Salinity On Interactions Between Epichloë Amarillans And Fusarium Spp. In American Beachgrass, Emma G. Mills, Dylan Habeeb, Natalie Christian, Connor Morozumi

The Cardinal Edge

Effects of Salinity on interactions between Epichloë amarillans and Fusarium spp. In American Beachgrass

Emma Mills, Dylan Habeeb, Natalie Christian, Connor Morozumi

Epichloë is a well-known genus of vertically transmitted fungal endophytes in many species of grasses. In Ammophila breviligulata (American beachgrass), Epichloë amarillans is a key endophyte species known to cause chemical and morphological changes to its host and provide protection from stressors. Additionally, Epichloë is thought to influence fungal endophyte community composition within its host. However, deepening research on the interaction of Epichloë with coexisting fungal endophytes may shed further light on its role in community composition. Additionally, …

Avaren-Fc, A Novel Immunotherapeutic, Recruits Nk Cells In B16f10 Melanoma Tumor Tissue, Vatsa Vemuri

The Cardinal Edge

Avaren-Fc, a Novel Immunotherapeutic, Recruits NK Cells in B16F10 Melanoma Tumor Tissue

Sreevatsa Vemuri¹, Katarina Mayer M.S.¹, Nobuyuki Matoba, Ph.D.^{1, 2, 3}

Department of Pharmacology and Toxicology¹, UofL Health-Brown Cancer Center², Center for Predictive Medicine³, University of Louisville School of Medicine

Abstract

Avaren-Fc (AvFc) is an experimental antibody-like molecule, consisting of a recombinant Avaren lectin translationally fused to the Fc region of human IgG1. This unique design targets N-linked high-mannose glycans, which are overrepresented on the surface of malignant cells, including melanoma. With limited effective therapies available for …

Experience With A Systematic Review Project From An Undergraduate Student Perspective, Maggie Schade, Bianca Welikson, Maria Kondaurova

The Cardinal Edge

Trauma exposure due to gun violence, homelessness, and/or substance abuse is prevalent in West Louisville, KY. In 2020, 65% of adults in KY reported one traumatic experience. Depression, as a result of trauma, affects significantly more adults in KY than nationwide (25.7% vs. 20.5%). It is known that depression affects the characteristics of child-directed speech (CDS), a specific register that caregivers use while interacting with their children. CDS is characterized by exaggerated prosody, more distinct vowels, shorter and structurally simpler sentences in comparison to adult-directed speech, and is an important predictor of language development. However, our knowledge of the effect …

Stress And Sleep In A Community Sample Of Preschool-Aged Children, Khadija Awale, Akira Isaac M.S., Alyssa Rodriguez M.S., Sara Bufferd Ph.D.

The Cardinal Edge

Stress influences sleep patterns, as elevated stress levels can decrease adequate sleep. However, research on this relationship in preschool-aged children is limited. The current study examined the relationship between stress and sleep in preschool-aged children and sought to evaluate associations between children’s stress and sleep, as well as parental psychopathology (i.e., anxiety and depression). Participants included N = 609 parents and their children ages three to five at Time 1. 368 of whom participated again when children were ages six to eight years old at Time 2. Participants completed study questionnaires, and children’s hair samples were taken to assess cortisol …

Urban Areas Are Associated With Earlier Breeding Timing In American Robins, Lola Hackle, Jennifer Wickes, Elise Mittlestat, Ashley Stine, Keegan Abeson, Carolina Villalona, Mikus Abolins-Abols

The Cardinal Edge

Climate change and urban environment have been shown to affect bird reproductive timing. In particular, urban development can create the so-called “heat islands” – urban areas that are hotter than the surrounding environment. While the primary cue birds use to time their reproduction is daylength, birds also use temperature as a supplementary cue to fine-tune their reproductive timing. Change in the timing of breeding may impact the survivability of nestlings due to temperature fluctuations and food availability. The American Robin (Turdus migratorius) is a widespread songbird in North American cities and rural areas. We sought to see if urban heating …

The Resilient Families Project: Promoting Resilience, Mindfulness And Belonging Through Community Engagement And Interactive Reading In At-Risk Adults, Sydney Higdon, Dillon Hepler, Lora D. Haynes, Ph.D., Angela Ely, B.A.

The Cardinal Edge

Founded in 2011, the University of Louisville’s Resilient Families Project (RFP) is a community-engaged initiative that promotes evidence-based habits of resilience, mindfulness, and happiness among adults experiencing homelessness and/or in the addiction recovery program at Wayside Christian Mission (WCM). Through weekly trauma-informed sessions, RFP aims to strengthen such things as a sense of family/community, emotional awareness, positive coping strategies and a growth mindset.

This presentation highlights RFP’s current curriculum, centered around our six core values and integrated content from select storybooks, to support healthy attachment relations, interactive reading, and a sense of purpose and belonging.

The current authors also describe …