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Neurosymbolic Counterpoint Generation, Paul D. Jarski Mar 2026

Neurosymbolic Counterpoint Generation, Paul D. Jarski

Master's Theses

Recent advancements in generative artificial intelligence have revolutionized music generation, yet research has predominantly focused on raw audio synthesis over music in symbolic form, i.e. a score. This thesis presents the first neurosymbolic model designed to generate imitative Renaissance counterpoint in symbolic (MIDI) format. By leveraging an autoregressive Transformer architecture, this research explores the capacity of deep learning models to manage independent voices and strict stylistic constraints.

We compare multiple data representation strategies with distinct tokenization methods. The proposed model incorporates a symbolic component that enforces fundamental contrapuntal rules. Additionally, this thesis contributes a preprocessed dataset of Renaissance polyphony, in …


A Simulation Framework For Edge Lane Roads And Bicycle Shared Roadways, Nick Sauciur Mar 2026

A Simulation Framework For Edge Lane Roads And Bicycle Shared Roadways, Nick Sauciur

Master's Theses

Edge Lane Roads, also referred to as Advisory Bike Lanes, are a shared roadway treatment that designates space for cyclists while allowing flexible use of the roadway by motorists. They are commonly applied on lower speed corridors and can be used both where roadway width is limited and where agencies seek to manage vehicle speeds, clarify cyclist positioning, or improve shared roadway operations. The configuration provides visually designated space for cyclists while allowing motorists to encroach into that space when yielding to opposing traffic. Although interest in these facilities is growing in North America, quantitative tools for evaluating their operational …


Tennessee Archivist 45, No. 2, Society Of Tennessee Archivists Mar 2026

Tennessee Archivist 45, No. 2, Society Of Tennessee Archivists

Tennessee Archivist newsletters

Spring 2026 issue of the Tennessee Archivist, a newsletter produced by the Society of Tennessee Archivists.


X-Ray Emission In Illustristng Circum-Cluster Environments: Ii. Possible Origins Of The Soft X-Ray Excess Emission, Celine Gouin, Daniela Galárraga-Espinosa, Massimiliano Bonamente, Stephen Walker, Mohammad Mirakhor, Richard Lieu, Clotilde Laigle, Etienne Bonnassieux, Charlotte Welker, Stefano Gallo, Tony Bonnaire, Jade Paste Mar 2026

X-Ray Emission In Illustristng Circum-Cluster Environments: Ii. Possible Origins Of The Soft X-Ray Excess Emission, Celine Gouin, Daniela Galárraga-Espinosa, Massimiliano Bonamente, Stephen Walker, Mohammad Mirakhor, Richard Lieu, Clotilde Laigle, Etienne Bonnassieux, Charlotte Welker, Stefano Gallo, Tony Bonnaire, Jade Paste

Publications and Research

Context. An excess of soft X–ray emission (∼0.2 − 1 keV) above the contribution from the hot intracluster medium (ICM) has been detected in a number of galaxy clusters, including the Coma cluster. The physical origin of this emitting medium above the hot ICM has not yet been determined, in particular, it is unclear whether it is thermal or nonthermal.

Aims. We investigate the gas phase and gas structure that reproduce the soft excess radiation from the cluster core to the outskirts best using simulations.

Method. By using the IllustrisTNG simulation (TNG300), we predict the radial profile of thermodynamic properties …


Single-Nucleus Transcriptomics, Pharmacokinetics, And Pharmacodynamics Of Cdk4/6 And Mtor Inhibition In A Phase 0/1 Trial Of Recurrent High-Grade Glioma., Kevin C Johnson, An-Chi Tien, Jun Jiang, James Mcnamara, Yu-Wei Chang, Chelsea Montgomery, Anita Desantis, Leonel Elena-Sanchez, Yoko Fujita, Seongho Kim, Avishay Spitzer, Paul Gabriel, William F Flynn, Elise T Courtois, Amy Hong, Jocelyn Harmon, Yoshie Umemura, Artak Tovmasyan, Jing Li, Shwetal Mehta, Roel G W Verhaak, Nader Sanai Mar 2026

Single-Nucleus Transcriptomics, Pharmacokinetics, And Pharmacodynamics Of Cdk4/6 And Mtor Inhibition In A Phase 0/1 Trial Of Recurrent High-Grade Glioma., Kevin C Johnson, An-Chi Tien, Jun Jiang, James Mcnamara, Yu-Wei Chang, Chelsea Montgomery, Anita Desantis, Leonel Elena-Sanchez, Yoko Fujita, Seongho Kim, Avishay Spitzer, Paul Gabriel, William F Flynn, Elise T Courtois, Amy Hong, Jocelyn Harmon, Yoshie Umemura, Artak Tovmasyan, Jing Li, Shwetal Mehta, Roel G W Verhaak, Nader Sanai

Faculty Research 2026

BACKGROUND: Outcomes for adult patients with high-grade glioma (HGG) remain poor, necessitating new treatment strategies. Key challenges include poor drug penetration in the brain and malignant cell state plasticity. Phase 0 studies identify agents that achieve target modulation through pharmacologically relevant brain concentrations.

METHODS: A Phase 0/1 clinical trial combined the 2 targeted inhibitors ribociclib (CDK4/6 inhibitor) and everolimus (mTOR inhibitor) in recurrent HGG patients, aiming to identify brain-penetrant combinations and assess their impact on malignant cell states. We enrolled 24 patients with recurrent HGG, characterized by CDKN2A/B deletion or CDK4/6 amplification, PTEN loss or PIK3CA mutations, and wildtype retinoblastoma …


Conditional Stat2 Knockout Mice As A Platform For Modeling Human Diseases., Tess Cremers, Nataliya Miz, Alexandra Afanassiev, Ling Yang, Kevin P Kotredes, Ana M Gamero Mar 2026

Conditional Stat2 Knockout Mice As A Platform For Modeling Human Diseases., Tess Cremers, Nataliya Miz, Alexandra Afanassiev, Ling Yang, Kevin P Kotredes, Ana M Gamero

Faculty Research 2026

Signal transducer and activator of transcription 2 (STAT2) is a key component of the type I interferon (IFN-I/III) signaling pathway, which is pivotal in host defense against cancer and viral infections and in shaping immune responses. Building on our previously reported conditional Stat2 knockout (KO) mouse, we expand its utility by validating additional tissue- specific models and exploring novel functional contexts. Mice carrying loxP-flanked Stat2 alleles were crossed with CMV-Cre, Cdx2-Cre or CD11c-Cre mice. Deletion of STAT2 was validated by PCR genotyping and western blotting in the relevant tissues. To confirm defec- tive IFN-I signaling with STAT2 deletion, IFN-β stimulation …


Prevalence Of, Edison Liu, Margaret Antonio, Tracy Nance, Francesca Menghi Mar 2026

Prevalence Of, Edison Liu, Margaret Antonio, Tracy Nance, Francesca Menghi

Faculty Research 2026

Purpose

BRCA1 promoter methylation (BRCA1meth) affects 20%-27% of triple-negative breast cancer (TNBC) and ovarian cancer (OvCa) and has therapeutic predictive value in both cancer types. BRCA1meth is established during early embryonic development as a constitutional event, and its detection in the peripheral blood cells of unaffected women associates with increased risk for breast cancer and OvCa. Thus, facile and sensitive assessment of BRCA1meth is an important component for both risk assessment and the therapeutic management of these cancer types.

Methods

We used the GRAIL circulating cell-free DNA (cfDNA)–based targeted methylation platform to quantify BRCA1meth in …


Improving Gene Isoform Quantification With Miniquant., Haoran Li, Dingjie Wang, Qi Gao, Puwen Tan, Yunhao Wang, Xiaoyu Cai, Aifu Li, Yue Zhao, Andrew L Thurman, Seyed Amir Malekpour, Ying Zhang, Roberta Sala, Andrea Cipriano, Chia-Lin Wei, Vittorio Sebastiano, Chi Song, Nancy R Zhang, Kin Fai Au Mar 2026

Improving Gene Isoform Quantification With Miniquant., Haoran Li, Dingjie Wang, Qi Gao, Puwen Tan, Yunhao Wang, Xiaoyu Cai, Aifu Li, Yue Zhao, Andrew L Thurman, Seyed Amir Malekpour, Ying Zhang, Roberta Sala, Andrea Cipriano, Chia-Lin Wei, Vittorio Sebastiano, Chi Song, Nancy R Zhang, Kin Fai Au

Faculty Research 2026

RNA sequencing has been widely applied for gene isoform quantification, but limitations exist in quantifying isoforms of complex genes accurately, especially for short reads. Here we identify genes that are difficult to quantify accurately with short reads and illustrate the information benefit of using long reads to quantify these regions. We present miniQuant, which ranks genes with quantification errors caused by the ambiguity of read alignments and integrates the complementary strengths of long reads and short reads with optimal combination in a gene- and data-specific manner to achieve more accurate quantification. These results are supported by rigorous mathematical proofs, validated …


Meta-Analysis Of Genetic Mapping Studies In Mice Reveals Candidate Epilepsy Modifier Genes That Are Outside The Current Drug Development Landscape., Giovanna L Durante, Anna L. Tyler, Rod C Scott, Amanda E Hernan, J Matthew Mahoney Mar 2026

Meta-Analysis Of Genetic Mapping Studies In Mice Reveals Candidate Epilepsy Modifier Genes That Are Outside The Current Drug Development Landscape., Giovanna L Durante, Anna L. Tyler, Rod C Scott, Amanda E Hernan, J Matthew Mahoney

Faculty Research 2026

OBJECTIVE: Despite decades of development in anti-seizure medications, ~30% of individuals remain refractory to all treatments, and none of the existing therapies are disease modifying. Identifying targets outside the current preclinical paradigm is critically important. This study aimed to characterize the landscape of current epilepsy treatments at the level of gene interaction networks and identify novel genetic modifiers of epilepsy as potential novel therapeutic targets.

METHODS: We performed a functional network analysis to score genes based on their interactions with known epilepsy genes, and we integrated these functional scores with population genetics data and drug tractability information. In parallel, we …


« À La Fois Une Fierté Et Un Vertige » : Dire Le Droit Des Personnes Et De La Filiation En Contexte De Réforme (2022-2025), Régine Tremblay Mar 2026

« À La Fois Une Fierté Et Un Vertige » : Dire Le Droit Des Personnes Et De La Filiation En Contexte De Réforme (2022-2025), Régine Tremblay

All Faculty Publications

Quelle chance d’écrire sur une réforme du Code civil du Québec pour célébrer les 50 ans du Centre Paul-André Crépeau ! Depuis l’arrivée au pouvoir de la Coalition Avenir Québec (CAQ) en 2018, le fond et la forme du droit des personnes et des familles ont été transformés. Entre 2021 et 2025, le gouvernement majoritaire de la CAQ a déposé quatre projets de loi, un chantier par étapes que le ministre de la Justice et Procureur général du Québec, M. Simon Jolin-Barette, qualifia pour sa part de « première réforme majeure »  en droit de la famille depuis 1980. Pour …


Ai & Policing: Knowledge Synthesis Report On The Governance & Use Of Artificial Intelligence By Police In Canada, Benjamin Perrin, Geoffrey Liew, Isabelle Sweeney Mar 2026

Ai & Policing: Knowledge Synthesis Report On The Governance & Use Of Artificial Intelligence By Police In Canada, Benjamin Perrin, Geoffrey Liew, Isabelle Sweeney

All Faculty Publications

Police services across Canada are using, or exploring, a broad range of artificial intelligence (AI) technologies, including facial recognition, location-based predictive policing, automated licence plate readers, AI-assisted police reports, object recognition and video analytics, social media monitoring, gunshot detection, probabilistic genotyping, and data mining.

While promising productivity and public safety benefits, these tools also raise various concerns and risks. Canada currently lacks AI-specific legislation and regulations governing these new technologies, or even a statement of principles on the governance and use of AI by police.


Ia Et Maintien De L'Ordre : Rapport De Synthèse Des Connaissances Sur La Gouvernance Et L'Utilisation De L'Intelligence Artificielle Par La Police Au Canada, Benjamin Perrin, Geoffrey Liew, Isabelle Sweeney Mar 2026

Ia Et Maintien De L'Ordre : Rapport De Synthèse Des Connaissances Sur La Gouvernance Et L'Utilisation De L'Intelligence Artificielle Par La Police Au Canada, Benjamin Perrin, Geoffrey Liew, Isabelle Sweeney

All Faculty Publications

Les services de police de partout au Canada utilisent, ou explorent, un large éventail de technologies d'intelligence artificielle (IA), y compris la reconnaissance faciale, le maintien de l'ordre prédictif basé sur la localisation, les lecteurs de plaques d'immatriculation automatisés, les rapports de police assistés par IA, la reconnaissance d'objets et l'analyse vidéo, la surveillance des médias sociaux, la détection de coups de feu, le génotypage probabiliste et l'exploration de données.

Bien que promettant des avantages en matière de productivité et de sécurité publique, ces outils soulèvent également diverses préoccupations et risques. Le Canada manque actuellement de mesures législatives et de …


Eeg Features And Rotterdam Head Ct Score Predict Early Favorable Outcome In Pediatric Severe Tbi, Xuexin Lu Mar 2026

Eeg Features And Rotterdam Head Ct Score Predict Early Favorable Outcome In Pediatric Severe Tbi, Xuexin Lu

Presentations

INTRODUCTION Accurate prognostication after pediatric severe TBI (sTBI) remains challenging. We examined the utility of continuous EEG (cEEG) and Rotterdam head CT score in predicting short-term favorable outcome. METHODS 7-yr (01/2018-12/2024) retrospective study of children aged 1.5-18 yrs admitted to our PICU with sTBI and receiving cEEG monitoring per institutional protocol. Early favorable outcome was defined as Pediatric Cerebral Performance Category scale 1-3 at PICU discharge. cEEG features (background, sleep architecture, reactivity, and seizure) during the 1st 12-hrs of monitoring and initial Rotterdam head CT scores were recorded. Demographics, GCS score, pupillary reactivity, injury severity score (ISS), clinical seizure, cardiac …


Bridging The Distance: Expanding Access To Mental Health Services In School, Griffin Gallagher, Arayah St John, Kaylie Svir Mar 2026

Bridging The Distance: Expanding Access To Mental Health Services In School, Griffin Gallagher, Arayah St John, Kaylie Svir

Master of Social Work Student Policy Advocacy Briefs

All students should have equitable access to mental health services in schools. In Minnesota, there has been an 11% increase in students experiencing long-term mental health challenges since 2016, and only 1 in 5 students receive the assistance they need. Students are experiencing a lack of access to mental health services in schools due to barriers of cost, transportation, shortage of support staff, and stigma. When mental health services are not provided in schools, this results in a decrease in school attendance, higher dropout rates, and negative school environments, affecting the long-term outcomes and needs of the child. Mental health …


Housing After Recovery: Expanding Access For Justice-Involved Individuals, Calvin Parzych, Melinda Gillen, Juliet Worayewaa, Mikayla Witter Mar 2026

Housing After Recovery: Expanding Access For Justice-Involved Individuals, Calvin Parzych, Melinda Gillen, Juliet Worayewaa, Mikayla Witter

Master of Social Work Student Policy Advocacy Briefs

Every human being deserves access to safe, stable housing, especially individuals in recovery from substance use disorders. These individuals face significant barriers to stable housing, especially when their criminal records are considered by landlords. This can pose a risk to potential relapse, homelessness, and overall struggle to maintain recovery. Addressing housing discrimination for all members of society, especially justice-involved individuals, can aid in resolving public health and social justice issues that continue to be a long-standing problem.


March 2026 Library News, University Libraries Mar 2026

March 2026 Library News, University Libraries

Library News

No abstract provided.


Bankrupt Crypto Organizations, Kara Bruce, Christopher K. Odinet, Andrea Tosato Mar 2026

Bankrupt Crypto Organizations, Kara Bruce, Christopher K. Odinet, Andrea Tosato

North Carolina Law Review

No abstract provided.


When You're Just Not "Indian" Enough: The Erosion Of Tribal Sovereignty In State V. Nobles And The Case For Deference To Tribes On Questions Of Indian Status, Daniel G. Sullivan Mar 2026

When You're Just Not "Indian" Enough: The Erosion Of Tribal Sovereignty In State V. Nobles And The Case For Deference To Tribes On Questions Of Indian Status, Daniel G. Sullivan

North Carolina Law Review

No abstract provided.


Hss 216 Introduction To Motivational Interviewing, Juline A. Koken Mar 2026

Hss 216 Introduction To Motivational Interviewing, Juline A. Koken

Open Educational Resources

This syllabus contains links to an OER textbook that was adopted for our Introduction to Motivational Interviewing course, along with additional links to OER videos and additional readings.


Hss 295, Juline A. Koken Mar 2026

Hss 295, Juline A. Koken

Open Educational Resources

This syllabus contains links to existing OER materials as well as additonal readings for our HSS 295 Community Organizing class.


Teaching On The Clock, Michael Burla Do Mar 2026

Teaching On The Clock, Michael Burla Do

Faculty Development Tips

No abstract provided.


The Emerging And Evolving Evidence Supporting Creatine As An Ergogenic Aid: History And Applications, Chad Kerksick, Drew Gonzalez, Jeffrey Stout, Scott Forbes, Darren Candow, Tim Ziegenfuss, Ronald Marshall, René Schwesig, Richard Kreider Mar 2026

The Emerging And Evolving Evidence Supporting Creatine As An Ergogenic Aid: History And Applications, Chad Kerksick, Drew Gonzalez, Jeffrey Stout, Scott Forbes, Darren Candow, Tim Ziegenfuss, Ronald Marshall, René Schwesig, Richard Kreider

Faculty Scholarship

Background

Creatine is one of the most extensively studied ergogenic aids, with over three decades of research supporting its role in exercise performance, recovery, and health.

Methods

This narrative review summarizes the historical development of creatine supplementation and evaluates evidence regarding its mechanisms, efficacy across active, athletic populations (e.g. strength, endurance, team-sport), and tactical (e.g. military, law enforcement) populations, and its safety profile.

Results

The evidence suggests that creatine enhances phosphocreatine resynthesis and cellular energy availability, resulting in consistent improvements in high-intensity exercise performance, training adaptations, lean body mass, strength, and power. Additional findings indicate that creatine may attenuate exercise-induced …


Analyzing Access To Livelihood Opportunities Among Migrants, Refugees And Asylum-Seekers In Egypt, Sara Sadek, Nada Hegazy, Shaimaa Gheith, Mahmoud Mansour Mar 2026

Analyzing Access To Livelihood Opportunities Among Migrants, Refugees And Asylum-Seekers In Egypt, Sara Sadek, Nada Hegazy, Shaimaa Gheith, Mahmoud Mansour

Faculty Journal Articles

The study “Access to livelihood opportunities among migrants, refugees and asylum- seekers in Egypt,” was conducted under the framework of the Egyptian Migration Hub (EHUB) project. It focused on underscoring the prospects of challenges with regards to the employment of such groups in the informal labor economy in Egypt considering the current limitations in the legal framework. The study adopted a qualitative method including 46 KIIs and 46 FGDs conducted in three governorates: Greater Cairo, Alexandria and Damietta. In December 2024 the law 164 governing refugee and asylum issues in Egypt was enacted with Article 18 stipulating the right to …


Portable Ice Cube Maker, Ayden Ziegler, Emiliano Hansen, Wyatt Engdahl, Dane Hansen Mar 2026

Portable Ice Cube Maker, Ayden Ziegler, Emiliano Hansen, Wyatt Engdahl, Dane Hansen

Mechanical Engineering

This Final Design Report outlines the senior design project undertaken by a team of mechanical engineering students at California Polytechnic State University, San Luis Obispo, for the development of a portable backpacking ice cube maker. The project aims to design, build, and test a lightweight, compact device that produces ice cubes for backpackers in remote outdoor environments. The goal is to create a functional prototype that is durable, user-friendly, and suitable for backcountry use. This document details background research, project objectives, and project plan, and current design status.


Argument-Based Consistency In Toxicity Explanations Of Llms, Ramaravind K. Mothilal, Joanna Roy, Syed Ishtiaque Ahmed, Shion Guha Mar 2026

Argument-Based Consistency In Toxicity Explanations Of Llms, Ramaravind K. Mothilal, Joanna Roy, Syed Ishtiaque Ahmed, Shion Guha

Health Services and Informatics Research

The discourse around toxicity and LLMs in NLP largely revolves around detection tasks. This work shifts the focus to evaluating LLMs’ reasoning about toxicity—from their explanations that justify a stance—to enhance their trustworthiness in downstream tasks. Despite extensive research on explainability, it is not straightforward to adopt existing methods to evaluate free-form toxicity explanation due to their over-reliance on input text perturbations, among other challenges. To account for these, we propose a novel, theoretically-grounded multi-dimensional criterion, Argument-based Consistency (ArC), that measures the extent to which LLMs’ free-form toxicity explanations reflect an ideal and logical argumentation process. Based on uncertainty quantification, …


Table Of Contents, Editorial Board, Law School Faculty And Administration Mar 2026

Table Of Contents, Editorial Board, Law School Faculty And Administration

Nevada Law Journal

No abstract provided.


Behind Every Case Is A Conversation, Donna Shestowsky Mar 2026

Behind Every Case Is A Conversation, Donna Shestowsky

Nevada Law Journal

Lawyers play a central role in guiding clients through critical decisions that shape the trajectory of litigation. Among the most consequential of these is the choice of procedures by which disputes will be resolved—whether through trial, mediation, arbitration, or other mechanisms. Despite the weight of these decisions, legal scholarship offers little guidance on how lawyers might structure conversations about procedural options. This Article seeks to address that gap by drawing on empirical research from psychology and related disciplines to develop recommendations for educating and counseling clients—particularly those with little or no prior exposure to the civil justice system—so that they …


Unlocking The Corporate Governance Potential Of Mutual Fund Investors, Jeffrey Manns Mar 2026

Unlocking The Corporate Governance Potential Of Mutual Fund Investors, Jeffrey Manns

Nevada Law Journal

America’s mutual fund governance has long consisted of a system of money manager dominance and shareholder impotence. While mutual funds pool together unprecedented sums of capital, investors historically have had no meaningful role in governance and have faced a choice of “love it or leave it” when it comes to their investments in mutual funds.

The controversy over mutual fund managers’ advocacy of Environmental, Social, and Governance (ESG) principles in portfolio companies has reinvigorated interest in repairing the dysfunctional principal-agent relationship between investors and money managers. The management of BlackRock, the world’s largest money manager, ignited an ESG voting controversy …


Immigration’S Prejudice Problem, S. Ellie Norton Mar 2026

Immigration’S Prejudice Problem, S. Ellie Norton

Nevada Law Journal

With immigration enforcement sharply rising, noncitizens increasingly face deportation with few constitutional protections. Yet many remain at least entitled to a fundamentally fair hearing before an immigration court. Even before the current administration, however, immigration courts had become notorious for systematically violating noncitizens’ due process rights. And while other scholars have suggested broadscale reforms to tackle this problem, statutory and regulatory change has become all but unachievable. This Article offers a new and timely solution: reforming the framework for direct review of immigration court due process violations. In most jurisdictions, noncitizens asserting these violations must prove on appeal not only …


Trademarks Beyond The Dictionary: A Corpus Linguistics Approach To The International Implementation Of The Rule Of Foreign Equivalents, George Mcmullin Mar 2026

Trademarks Beyond The Dictionary: A Corpus Linguistics Approach To The International Implementation Of The Rule Of Foreign Equivalents, George Mcmullin

Nevada Law Journal

No abstract provided.