Digital Commons Network^™

A Novel Piggyback Strategy For Mrna Delivery Exploiting Adenovirus Entry Biology, Myungeun Lee, Paul J Rice-Boucher, Logan Thrasher Collins, Ernst Wagner, Lorenzo Aulisa, Jeffrey Hughes, David T Curiel

2020-Current year OA Pubs

Molecular therapies exploiting mRNA vectors embody enormous potential, as evidenced by the utility of this technology for the context of the COVID-19 pandemic. Nonetheless, broad implementation of these promising strategies has been restricted by the limited repertoires of delivery vehicles capable of mRNA transport. On this basis, we explored a strategy based on exploiting the well characterized entry biology of adenovirus. To this end, we studied an adenovirus-polylysine (AdpL) that embodied "piggyback" transport of the mRNA on the capsid exterior of adenovirus. We hypothesized that the efficient steps of Ad binding, receptor-mediated entry, and capsid-mediated endosome escape could provide an …

Structural And Functional Studies Of Mtr4 And The Tramp Rna Surveillance Complex, Sean Johnson

Funded Research Records

No abstract provided.

3d Pore Structure Characterization Of Stored Grain Bed, Charles Nwaizu, Qiang Zhang, Christiana Iluno

Department of Food Science and Technology: Faculty Publications

An image analysis technique for reconstruction of the complex 3D pore structure within bulk grain from 2D section images was presented. The technique relies on aligning successive 2D images of cut-sections obtained from colored-wax solidified soybean grain beds, which were then subjected to image processing using ImageJ software developed by the National Institute of Health (NIH, Bethesda, Md.) for the reconstruction and visualization of different airflow paths within the bulk grain. Porosity and tortuosity values were quantified from the 3D image volume and 3D reconstructed inter-connected airflow paths to develop empirical mathematical models for predicting porosity and tortuosity as a …

Argentina Product Exports And Imports To China, World Bank/World Bank Group

Documents

No abstract provided.

Digitalization And Tax-Motivated Income Shifting, Devenni Putri Fau, Lestari Kurniawati

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

Numerous studies show that the tax rate difference between parent and subsidiaries as well as among subsidiaries acts as the incentive for income shifting between multinational corporations (MNCs). Digital business models that emerged as an impact of digital transformation may exacerbate income shifting by MNCs. However, empirical studies to support the relation between digital business models and income shifting is still scarce. Thus, this study examined whether Indonesia’s foreign-owned manufacturing companies shift income in respect to its foreign-parent tax rate and if the level of digitalization exacerbates the practice. This study used the income-shifting approach by Hines and Rice (1994) …

The Effectiveness Of The Aceh Ombudsman Representative’S Maladministration Handling: An Insider Perspective, Muazzinah Muazzinah, Saiful Akmal, Amrul Fadhil, Reza Fathurrahman

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

The Ombudsman of the Republic of Indonesia oversees public services, particularly timely responses to reports. Since 2018, the Aceh Representative of the Indonesian Ombudsman handled 150 reports. It is interesting to investigate how well the Ombudsman dealt with these reports. This study examines the effectiveness of the Aceh Representative of the Indonesian Ombudsman in handling reported maladministration cases using a qualitative approach. The research data were gathered through interviews and document reviews by referring to Steer’s (1976) formulation of organization effectiveness, which includes productivity, adaptability, communication, job satisfaction, and human resources. The productivity, communication, and flexibility indicators are adequately effective, …

Synthesizing And Printing Of Tin Oxide Nanoparticles Using A Single Ultrafast Laser System: A Feasibility Study, Enrique Contreras Lopez, Farid Ahmed, Jianzhi Li

Manufacturing & Industrial Engineering Faculty Publications

In laser-based manufacturing, processing setup customization is one of the popular approaches used to enhance diversity in material processing using a single laser. In this study, we propose setup design modification of an ultrafast laser system to demonstrate both Tin Oxide (SnO2) nanoparticle synthesis from bulk metal, and post printing of said nanoparticles using Laser Induced Forward Transfer (LIFT) method. Using the Pulse Laser Ablation in Liquid (PLA-L) method, nanoparticles were synthesized from a bulk tin metal cube submerged in distilled water. Such nanoparticles dispersed in water can form colloidal ink that can be used for different printed electronics applications. …

How Is The Transfer Pricing Concept “Arm’S Length Principle” Applied In Indonesia?, Maria R.U.D. Tambunan

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

The research is aimed at analyzing how the arm’s length principle has been applied to transfer pricing cases in Indonesia. The arm’s length principle has become a global formula used by entities to ascertain that the transaction value has been done in an acceptable manner. The arm’s length principle has also become a fundamental basis in Indonesian tax regulations to assess the fairness of price for transactions undertaken by multinational entitles with their affiliation located outside the Indonesia’s jurisdiction. This research used qualitative approach and qualitative research method. The research shows that the manufacturing entities in Indonesia are mostly contract …

Determinants Of Entrepreneurial Intention: A Study On Indonesian Students, Satriadi Satriadi, Abu Muna Almaududi Ausat, D. Yadi Heryadi, Warkianto Widjaja, Ade Risna Sari

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

Finding jobs for university graduates is becoming more difficult as the number of job opportunities available is not proportional to the number of graduates. This situation is aggravated by the low interest of the Indonesian population in entrepreneurship, which is at roughly 3.1%. This study aims to investigate the effect of entrepreneurial self-efficacy, creativity, attitude toward entrepreneurship, social media, entrepreneurial culture, and motivation on student’s entrepreneurial intentions. Social media is warranted in the study as the respondents are in the group of millennials. A quantitative method was used. The data analysis employed Structural Equation Modelling (SEM) with Partial Least Squares …

Experimental Investigation Of The Performance And Emission Characteristics Of Methanol-Ethanolgasoline Blending With Iso-Butanol Additive On The Spark-Ignition Engine, Mussa Demewez Ali, Samson Mekbib Atnaw, Adem Siraj Mohammed

Platform: A Journal of Engineering

Nowadays, alternative fuels for internal combustion engines (IC) have gained traction due to environmental concerns and the necessity to reduce reliance on fossil fuels. Iso-butanol is an alternative fuel with low emissions that can be used in IC engines. The performance and emissions of a single-cylinder spark-ignition (SI) engine running on pure gasoline and iso-butanol additives (iB) at various engine load and blending ratios of EM10, EM10iB3, EM10iB5, and EM10iB10 were investigated experimentally in existing dual ethanol-methanol-gasoline blended fuel (EM10). The calorifc value of the fuel sample containing iso-butanol additive is 6.3% higher than that of the EM10 blended fuel. …

Rearward Visibility Assessment For Selected Passenger In Asean Countries, Badruzzaman A. Rahman, Muhammad H.F. Sohimi, Mior A. M. Said, Tengku N.A.T. Kamaruddin, Nurulakmar A. Husain, Siti N.M. Jamil, Mohammad S. Nasif, Ridway Balaka

Platform: A Journal of Engineering

ASEAN region consists of the greatest number of motorcycle-related accidents with severe and fatal casualties in Asia. Limited or blocked rearward visibility of vehicles has long been viewed as one of the causes of motorcycle accident. In this study, the rearward visibility of sixteen passenger vehicles have been assessed and analyzed using a new assessment based on some aspects of ECE46 and FMVSS III international protocols for Class I (internal rear-view mirror) and Class III (side-view mirror). A novel scoring system based on the average width of underbone-type motorcycles in Malaysia and Indonesia is proposed to highlight the importance of …

Investigation Of Clay Stabilizer Potential For High Clay Content Formation, Nur Khairul Bariyyah Mohd Nazri, Nur Asyraf Md Akhir

Platform: A Journal of Engineering

Clay swelling has been studied for decades due to its damaging problem in the reservoir. It has caused permeability impairment due to blockage at the pore throat and reduction of the available pore spaces in the reservoir. The past few decades have seen rapid development of clay stabilizers to treat clay minerals near-wellbore region areas. However, there a limited study investigating the potential of clay stabilizers to prevent clay swelling throughout the reservoir. The present study aimed to investigate the potential of potassium chloride (KCl) and Poly-diallyldimethylammonium chloride (PolyDADMAC) as cationic clay stabilizers to mitigate the clay swelling phenomenon throughout …

Optimization Of Raw Mix Design Of Clinker Production: A Case Study In Cement Industry, Barath Ponnusamy, Hilmi Hussin, Ainul Akmar Mokhtar, Masdi Muhammad

Platform: A Journal of Engineering

Raw mix design refers to the raw materials' quantitative proportions to achieve clinker with the desired chemical and mineralogical composition. The existing method used to formulate the raw mix design is based on iterative laboratory trials, which is time-consuming and heavily relies on the chemist's experience. Considering the negative environmental impacts, optimizing the raw mix design has become one of the major concerns among the cement players. Thus, the objective of this research is to optimize raw mix design with minimum cost while satisfying the critical clinker quality control targets. This study explored the Linear Programming (LP) model to achieve …

Prediction Of Soil Bearing Capacity Using Soft Computing Techniques, Awaisu Shafu Ibrahim, Ahmad Idris, Murtala Umar

Platform: A Journal of Engineering

The nature and manner in which structures are collapsing in Nigeria are alarming. It creates a room in which structural engineers, the building industry, government, estate developers, building consultants and other relevant stakeholders in the department building industry ask many questions about how and what is behind the sudden collapse of structures. Therefore, this research aimed to predict the ultimate bearing capacity of the square, strip and circular footing from shearing strength parameters using ANN and ANFIS. This paper, 200 data sets were used to develop the model; 75% were used for training and 25% for testing the model. ANN …

Analysis Of The Need For Legal Protection For Doctors In Teleconsultation Services Towards The Covid-19 Endemic In Indonesia, Mila Fitriana, Anhari Achadi

Journal of Indonesian Health Policy and Administration

Teleconsultation is a form of telemedicine that has developed rapidly during the COVID-19 pandemic. Clinical teleconsultation provides remote clinical consultation services to assist in establishing a diagnosis, and/or providing treatment considerations/advice. There are several issues in telemedicine, including ethical and legal issues. This study aims to find ethical and legal issues related to teleconsultation services after the COVID-19 pandemic. This research uses normative legal research methods. The laws and regulations that are reviewed by the researcher are those that are still valid in the Republic of Indonesia until June 2022. Researchers compare teleconsultation regulations and laws that were in effect …

Analysis Of Factors Related To Intention-To-Use Telemedicine Services (Teleconsultation) In Jabodetabek Residents During The Covid-19 Pandemic In 2021, Isna Mutiara Salsabila, Kurnia Sari

Journal of Indonesian Health Policy and Administration

The emergence of COVID-19 pandemic has made it difficult for people to access health services. According to JKN statistics, FKTP visits was decreased from 337.69 million (2019) to 193.03 (2021). Teleconsultation, a type of telemedicine, could be the right solution so that people can still access the health services they need and protect themselves from the spread of COVID-19. There was an increase in the use of several teleconsultation applications in Indonesia during pandemic, from 4 million to more than 15 million people. However, this rate is only 7.63% of the internet users and 5.6% of the total population of …

Comment Letter For: Quality Assurance Project Plan: Long-Term Operation And Maintenance Of Railroad Assets, For Bnsf Railway Company And Union Pacific Railroad, Butte Priority Soils Operable Unit (Dated May 2022), Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

State Of Utah Plaintiff - Petitioner, V. Alfonso Valdez, Defendant - Respondent : Brief Of Petitioner, Utah Supreme Court

Utah Supreme Court Briefs (2021– )

On Writ of Certiorari to the Utah Court of Appeals

EMILY ADAMS, FREYJA JOHNSON, Counsel for Respondent

CHRISTOPHER A. BATES, SEAN D. REYES, MELISSA A. HOLYOAK, THOMAS B. BRUNKER, Counsel for Petitioner

Using Sentinel-3 Satellite Imagery For Cyanobacteria Development Monitoring, Jillian Greene

Honors Projects

Great Lakes basins and inland waterways experience increased harmful algal bloom (HAB) production as a result of eutrophication– excess nutrient loading into waterways from agriculture and urbanization. Muskegon Lake, an estuary located on the eastern coast of Lake Michigan, was classified as a Great Lakes Area of Concern in 1985 due to severe HABs from several impairments including agricultural runoff and industrial waste dumping. Because of the ecosystem and human health threats posed by HABs such as wildlife and human illness and drinking water contamination, monitoring the abundance of HABs in inland waterways is imperative. The goal of this study …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.

Quarterly Report - 1st Quarter, July 1 - September 30, 2022, Etsu Foundation, East Tennessee State University

ETSU Foundation Quarterly Reports

No abstract provided.

System And Information Qualities In Mobile Fitness Apps And Their Effects On User Behavior And Performance, Mobark Q. Aldossari, Quynh N. Nguyen, Anh Ta, Steven A. Schulz

Management Faculty Publications

Grounded in goal setting theory and other IS models, this study introduces a robust model, that examines the determinants of MFA goal setting and goal tracking use, and their impact on user behavior and achievement. The empirical results show that system quality and information quality are two key determinants of MFA goal setting and goal tracking use, which significantly influence a user’s goal achievement and behavioral change in terms of physical activities.

A Seat For Everyone At The Longest Table, Sydney Pender

University of Mississippi News

UM hosts students, faculty, staff, community members for dinner and diverse discussions

Banning Books Threatens Freedom Of Speech, Clara Turnage

University of Mississippi News

UM librarian shares concerns about protecting diversity of opinion and perspective

Denise Knighton Retires After Almost 40 Years, Clara Turnage

University of Mississippi News

UM associate registrar leaves legacy of dedication

Psychological Flow And Its Relationship To The Performance Of The Human Wheel Skill On The Floor Movement Mat In The Artistic Gymnastics Of Students, Zena Abdul-Salam, Maha Haqqi

Modern Sport

The concept of psychological audit is closely related to the learning experience. The successful student is the one who spends all his energy and effort in learning and uses all tools and means to search for information and creates an atmosphere that makes him integrate into the material he is learning without looking at any external sign, but the thing that motivates and motivates him is an internal thing. Its source is his enjoyment of what he is doing as it affects his mastery of the skill of the human wheel for female students, and the aim of the research …

Classroom Management Obstacles Facing Physical Education Teachers In Secondary Schools, Sarah Abbas, Njlaa Abbas

Modern Sport

The importance of classroom management emerges from the importance of the student as the focus and goal of the educational process. Effective classroom management leads to effective teaching in order to achieve educational goals. Therefore, work should be done to overcome the obstacles and problems that hinder the teacher’s work through his management of his class. As for the research problem, the two researchers decided to identify the most important obstacles that physical education teachers face in their classroom management in schools. The two researchers identified the research community by the practical method of physical education teachers for secondary schools …

The Effect Of The Intustel Model In Learning The Skills Of Transmitter And Transmitter Receiving Volleyball For Female Students, Dania Salman, Shaymaa Jaafer

Modern Sport

The aim of the research is to use the Intustel model, and to identify the effect of the Intustel model in learning the skill of sending and receiving the balls that have been sent in volleyball (2020-2021). The research sample consisted of (20) female students who were chosen randomly by lottery from the two divisions (B-D), and the sample was divided into two experimental and control groups with (10) students for each group and a percentage (33, 10) of the original community, and the implementation period lasted The educational program (16) weeks and by (1) one educational unit per week, …

The Effect Of The Cognitive According To The Cognitive Acceleration Strategy To Reduce Cognitive Failure And Development Of Some Motor Sentences With The Hook Weapon For Students, Ghada Ibraheem, Intisar Uaid Ali

Modern Sport

The research aims to prepare an educational program according to the cognitive acceleration strategy to reduce cognitive failure and develop some motor sentences in the blind weapon for students, prepare the cognitive failure scale for students, and identify the impact of the educational program according to the cognitive acceleration strategy in reducing cognitive failure and developing some motor sentences in the weapon Blinds for students, and the two researchers followed the experimental approach by designing two equal groups with pre and post tests, and the research community was determined by students of the third stage, College of Physical Education and …

Building And Codifying A Scale Of Problems And Obstacles To The Application Of The Law Of Athletes, Champions And Pioneers, Asia Fadhil, Luma Sameer

Modern Sport

Through downloading, direct petition and sports, the two researchers noticed that there is a reluctance to some of the necessary measures and needs that the institution must take, as well as the negatives and obstacles that accompany a law for the law of athletes, champions and pioneers. Their dear country, and it is our duty to respond, even in a small part, to them, and accordingly, this study attempts to address a real problem facing the Law of Athletes, Champions and Pioneers. and pioneers. To achieve the objectives of the research, the two researchers used the descriptive approach in the …