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Articles 668851 - 668880 of 5207164
Full-Text Articles in Entire DC Network
Colorblind Capture, Jonathan Feingold
Colorblind Capture, Jonathan Feingold
Faculty Scholarship
We are facing two converging waves of racial retrenchment. The first, which arose following the Civil Rights Movement, is nearing a legal milestone. This term or the next, the Supreme Court will prohibit affirmative action in higher education. When it does, the Court will cement decades of conservative jurisprudence that has systematically eroded the right to remedy racial inequality.
The second wave is more recent but no less significant. Following 2020’s global uprising for racial justice, rightwing forces launched a coordinated assault on antiracism itself. The campaign has enjoyed early success. As one measure, GOP officials have passed, proposed or …
Poly Under Pandemic: A Pilot Survey Examining Cal Poly Slo’S Student Body During The Covid-19 Pandemic, Brett Vollrath
Poly Under Pandemic: A Pilot Survey Examining Cal Poly Slo’S Student Body During The Covid-19 Pandemic, Brett Vollrath
Journalism
The following is a survey of Cal Poly SLO students and alumni who had attended the university while major pandemic restrictions were in place. The paper is based around a pilot survey and data set.
The introduction provides background on the problem and how this survey was prepared.
The literature review details research conducted during the pandemic, which was used to guide the survey's focus questions.
The survey section details the questions asked of respondents. Respondents were first asked demographic questions to establish reference points. They were then asked questions on different aspects of student life, such as mental health, …
Exploring The Experiences Of Runners With Visual Impairments And Sighted Guides, Lindsay E. Ball, Lauren J. Leiberman, Pamela Beach, Melanie Perreault, Jason Rich
Exploring The Experiences Of Runners With Visual Impairments And Sighted Guides, Lindsay E. Ball, Lauren J. Leiberman, Pamela Beach, Melanie Perreault, Jason Rich
Human Movement Studies & Special Education Faculty Publications
: Running is a popular sport, and, with simple modifications, it can be accessible for individuals with visual impairments, particularly with a sighted running guide. The purpose of this study is to examine the experiences of runners with visual impairments and sighted running guides. Adopting a descriptive qualitative approach to guide data collection analysis and interpretation, seven runners with visual impairments and four sighted running guides were recruited and interviewed. The analysis identified four major themes: (1) benefits, (2) barriers, (3) advocacy, and (4) communication. The identified themes illustrate the influence of participation in running on the health and relationships …
Equivocal Originalism, Gary S. Lawson
Equivocal Originalism, Gary S. Lawson
Faculty Scholarship
"Originalism" is a term shrouded in ambiguity and ripe for equivocation. A recent article by Stephen Sachs in the Harvard Law Review tries to clarify the discussion by distinguishing between originalism as a decision standard, or a set of criteria for ascertaining the truth conditions for propositions, and a decision procedure, or a mechanism for ascertaining whether those truth conditions are satisfied in any given context. That is a helpful distinction, but it still leaves much room for multiple and confusing uses of the term originalism. Jumping off from comments on Professor Sachs's article by Mitchell Berman and Judge Andrew …
Green, Or Greed? A Fresh Perspective On The Valuation Of Conservation Easements, Alan L. Feld, Jacob Nielson, Theodore S. Sims
Green, Or Greed? A Fresh Perspective On The Valuation Of Conservation Easements, Alan L. Feld, Jacob Nielson, Theodore S. Sims
Faculty Scholarship
Charitable contributions of "conservation easements" have since 1980 allowed high-income taxpayers to shelter income from taxation through overvalued deductions. Overvaluation has increased dramatically in the past 20 years: a 2016 study of all easement decisions since 1980 reported that while overvaluation had averaged by a factor of two before 1994, it averaged by a factor of ten for decisions between 1994 and 2016. SOI data disclose that aggregate easement contributions deducted on Schedule A grew from $2.26 billion in 2015 to $6.5 billion in 2018 (the most recent year available). A recent report by supporters of conservation easements acknowledges that …
Functionality Of The Gracilis Collateral Is Impaired Following Arteriogenesis And Cell Transplantation, Ada A. Tadeo
Functionality Of The Gracilis Collateral Is Impaired Following Arteriogenesis And Cell Transplantation, Ada A. Tadeo
Biomedical Engineering
Peripheral Arterial Disease involves narrowed arteries, reducing blood flow to limbs. Increasing blood flow to those extremities is possible by redirecting the blood to flow through natural bypasses (i.e. collateral arteries), which can enlarge via arteriogenesis to maintain blood supply once the prominent arteries have become occluded. This study aims to investigate how arteriogenesis affects collateral function, if myoblast transplantation can stimulate collateral growth, and how that in turn may affect collateral function. Femoral artery ligation was performed to mimic the blockage that occurs in patients with ischemic diseases on lean mice and mice with diet induced obesity (DIO). A …
Telomere Biology Disorders: Time For Moving Towards The Clinic?, Luis F Z Batista, Inderjeet Dokal, Roy Parker
Telomere Biology Disorders: Time For Moving Towards The Clinic?, Luis F Z Batista, Inderjeet Dokal, Roy Parker
2020-Current year OA Pubs
Telomere biology disorders (TBDs) are a group of rare diseases caused by mutations that impair telomere maintenance. Mutations that cause reduced levels of TERC/hTR, the telomerase RNA component, are found in most TBD patients and include loss-of-function mutations in hTR itself, in hTR-binding proteins [NOP10, NHP2, NAF1, ZCCHC8, and dyskerin (DKC1)], and in proteins required for hTR processing (PARN). These patients show diverse clinical presentations that most commonly include bone marrow failure (BMF)/aplastic anemia (AA), pulmonary fibrosis, and liver cirrhosis. There are no curative therapies for TBD patients. An understanding of hTR biogenesis, maturation, and degradation has identified pathways and …
Antimicrobial Stewardship For Sepsis In The Intensive Care Unit: Survey Of Critical Care And Infectious Diseases Physicians, M Cristina Vazquez Guillamet, Jason P Burnham, Maria Pérez, Marin H Kollef, Constantine A Manthous, Donna B Jeffe
Antimicrobial Stewardship For Sepsis In The Intensive Care Unit: Survey Of Critical Care And Infectious Diseases Physicians, M Cristina Vazquez Guillamet, Jason P Burnham, Maria Pérez, Marin H Kollef, Constantine A Manthous, Donna B Jeffe
2020-Current year OA Pubs
OBJECTIVE: To evaluate the attitudes of infectious diseases (ID) and critical care physicians toward antimicrobial stewardship in the intensive care unit (ICU).
DESIGN: Anonymous, cross-sectional, web-based surveys.
SETTING: Surveys were completed in March-November 2017, and data were analyzed from December 2017 to December 2019.
PARTICIPANTS: ID and critical care fellows and attending physicians.
METHODS: We included 10 demographic and 17 newly developed, 5-point, Likert-scaled items measuring attitudes toward ICU antimicrobial stewardship and transdisciplinary collaboration. Exploratory principal components analysis (PCA) was used for data reduction. Multivariable linear regression models explored demographic and attitudinal variables.
RESULTS: Of 372 respondents, 315 physicians had …
Incisionless Targeted Adeno-Associated Viral Vector Delivery To The Brain By Focused Ultrasound-Mediated Intranasal Administration, Dezhuang Ye, Jinyun Yuan, Yaoheng Yang, Yimei Yue, Zhongtao Hu, Siaka Fadera, Hong Chen
Incisionless Targeted Adeno-Associated Viral Vector Delivery To The Brain By Focused Ultrasound-Mediated Intranasal Administration, Dezhuang Ye, Jinyun Yuan, Yaoheng Yang, Yimei Yue, Zhongtao Hu, Siaka Fadera, Hong Chen
2020-Current year OA Pubs
BACKGROUND: Adeno-associated viral (AAV) vectors are currently the leading platform for gene therapy with the potential to treat a variety of central nervous system (CNS) diseases. There are numerous methods for delivering AAVs to the CNS, such as direct intracranial injection (DI), intranasal delivery (IN), and intravenous injection with focused ultrasound-induced blood-brain barrier disruption (FUS-BBBD). However, non-invasive and efficient delivery of AAVs to the brain with minimal systemic toxicity remain the major challenge. This study aims to investigate the potential of focused ultrasound-mediated intranasal delivery (FUSIN) in AAV delivery to brain.
METHODS: Mice were intranasally administered with AAV5 encoding enhanced …
Lung Allograft Standardized Histological Analysis (Lasha) Template: A Research Consensus Proposal, Fiorella Calabrese, Chieh-Yu Lin, Et Al.
Lung Allograft Standardized Histological Analysis (Lasha) Template: A Research Consensus Proposal, Fiorella Calabrese, Chieh-Yu Lin, Et Al.
2020-Current year OA Pubs
BACKGROUND: Routine monitoring of lung-transplanted patients is crucial for the identification of immunological and non-immunological complications. Determining the etiology of acute allograft dysfunction, particularly in alloimmune-mediated disorders, relies heavily on the lung biopsy with histopathologic analysis. Standardization of the pathologic diagnosis of rejection (e.g., cellular and antibody-mediated) is based on consensus statements and guidelines, indicating the importance of a multidisciplinary approach to achieve a definitive etiological diagnosis. In addition to these statements and guidelines, refinements and standardizations are feasible through systematic analysis morphological, immunophenotypic and molecular alterations observed in transbronchial biopsies. This study is to identify key morphologic features to …
From Shaq To Serena Williams: An Analysis Of Celebrity Spacs, John Boyar
From Shaq To Serena Williams: An Analysis Of Celebrity Spacs, John Boyar
Senior Theses
Special Purpose Acquisition Companies (SPACs) surged in popularity in 2020 and 2021. For the first time in U.S. history, more SPAC IPOs occurred in a particular year than traditional IPOs and direct listings. Amidst the increase in SPAC IPOs, an expanding number of celebrities became involved with these investment vehicles. This thesis investigates the trend of celebrity backed SPACs by examining how celebrity involvement or association with a SPAC may affect the performance of these equities in the market.
This study examines the SPAC period returns, deSPAC period returns, IPO sizes, deal lengths, and PIPE financing amounts of 339 SPAC …
Covid-19 And The College Student Experience, Benjamin Cochran
Covid-19 And The College Student Experience, Benjamin Cochran
Senior Theses
In March of 2020, COVID-19 consumed the globe, affecting individuals’ physical and mental health. Physical health disparities among states of different political affiliations became clearer as the pandemic continued unrelentingly, but mental health disparities were not. This thesis attempted to note any mental health disparities among college students in states of both political affiliations across the country through an online survey. The 23-question survey was completed by 97 undergraduates at six universities - three in liberal states and three in conservative states. Respondents at universities in the liberal states rated their university and the state in which it is located …
The Impact Of Strength Training On Mental Health In Nursing Students During And Following The Covid-19 Pandemic, Emma Epperly
The Impact Of Strength Training On Mental Health In Nursing Students During And Following The Covid-19 Pandemic, Emma Epperly
Senior Theses
Stress, anxiety, and depression are noticeably prevalent in the nursing student population. There is a great deal of pressure placed on nursing students for high academic achievement and performance in the clinical settings. For many nursing students, the coronavirus disease 2019 (COVID-19) pandemic exacerbated existing or created new mental health struggles. Despite the severity of this problem, there is a great hesitancy for students to seek treatment because of the stigma around mental health diagnoses. With this in mind, strength training is an effective mode of exercise for improving symptoms of anxiety and depression, indicating that it would be a …
The Good Soldier: A Look Into The Stigma And Stereotypes Of The Us Military, Riley Margaret Bachmann
The Good Soldier: A Look Into The Stigma And Stereotypes Of The Us Military, Riley Margaret Bachmann
Senior Theses
“The Good Soldier: A Look at the Stigma and Stereotypes of the US Military” examines the stigma associated with mental health as well as gender stereotypes and bias in the United States military. It uses my personal experience in the Air Force Reserve Officer Training Corps program as well as research to show the institutionalization of stigma and stereotypes. The purpose of this thesis is to spread awareness and question why this stigma exists. I will find correlations between mental health and stereotypes and their overlap as a service member in the military. My personal memoir coupled with research on …
Is Teacher Pay Adequate: Teachers' Opinions On Their Expectations, Requirements, And Pay In Columbia, Sc, Presley Garrard
Is Teacher Pay Adequate: Teachers' Opinions On Their Expectations, Requirements, And Pay In Columbia, Sc, Presley Garrard
Senior Theses
The notion of raising teacher pay has been a topic for discussion in the past decades. There are many reasons to raise teacher pay. This paper discusses expectations, requirements, and the professionalism of teachers as being some of the reasons for increasing teacher pay by analyzing peer-reviewed articles and journals. There is an argument that teacher pay does not need to be raised and this argument is acknowledged. In addressing teacher pay, primary research sought teachers’ opinions on the demands and expectations of their job and their pay as an accurate reflection of such demands and expectations. This data was …
The Ethical Perceptions Of Dog Tail Docking Amongst Owners And Veterinarians In South Carolina, Hannah Ellen Steinberg
The Ethical Perceptions Of Dog Tail Docking Amongst Owners And Veterinarians In South Carolina, Hannah Ellen Steinberg
Senior Theses
This thesis aimed to discover, in depth, what tail docking of dogs is, why it is currently in practice, what the controversial opinions surrounding it are, how the opinions differ when taking into account the professionals of the field versus owners and breeders, and how it can be addressed in the future to treat our animals as humanely as possible.
Based on the surveying of South Carolinian owners, breeders, and veterinarians, it was discovered that dog tail-docking procedures are overwhelmingly used for cosmetic or aesthetic purposes, with the aim being to match breed standards. There was a disagreement amongst those …
The Implications Of Fraud On Non-Shareholder Stakeholders, Chasen P. Spicer
The Implications Of Fraud On Non-Shareholder Stakeholders, Chasen P. Spicer
Senior Theses
Popular news outlets such as The New York Times or The Wall Street Journal frequently release articles detailing the financial losses incurred by shareholders of a company that have recently been publicly exposed for their fraudulent activities (Shumsky, 2018; Whitmire, 2005). Given that shareholders are visibly impacted by fraud, it is also reasonable to believe that other stakeholders experience repercussions from the fraudulent activities carried out by the company (Velikonja, 2013). To provide more insight into the implications of fraud incurred by non-shareholder stakeholders, I conduct a case study analysis of HealthSouth’s various fraudulent activities between the years of 1997 …
Understannding Education Variances In Our World: An Analysis Of Private And Public Education On Graduates' Effects In Society, Ja'quon L. Williams
Understannding Education Variances In Our World: An Analysis Of Private And Public Education On Graduates' Effects In Society, Ja'quon L. Williams
Senior Theses
As of late, the debate between public and private high school education has become a common topic of conversation. The question arises, which option of schooling is best for its students? While fairness may come into play, this thesis is not focused on discovering injustices in the systems. This thesis analyses data and features from public and private high schools to determine which system provides the best education and opportunities for its students to be successful in postgraduation. From the analyzed data, one can conclude that private high schools provide better opportunities and better education for students than public high …
Brown Bear, Brown Bear, How Should We Read: Applying Principles Of Literacy Development To Shared Book-Reading Experiences, Kalika Melody Burnett Bridwell
Brown Bear, Brown Bear, How Should We Read: Applying Principles Of Literacy Development To Shared Book-Reading Experiences, Kalika Melody Burnett Bridwell
Senior Theses
Literacy has long been recognized as critical to success in and out of the classroom (Duchouquette, 2014; Hernandez, 2011; National Center for Family Literacy, 2008), having significant impact on students’ ability to achieve positive outcomes in academic, professional, social, and personal domains. Research suggests that this correlation is established at an early age (Cunningham & Zibulsky, 2011, Storch & Whitehurst, 2002, National Center for Family Literacy, 2008), giving urgency to the provision of high-quality early literacy education and to the identification of best practices in this area. Outside of explicit teaching, one of the most popular of these practices is …
January 6, Ambiguously Inciting Speech, And The Overt-Acts Rule, Alan Z. Rozenshtein, Jed Handelsman Shugerman
January 6, Ambiguously Inciting Speech, And The Overt-Acts Rule, Alan Z. Rozenshtein, Jed Handelsman Shugerman
Faculty Scholarship
A prosecution of Donald Trump for his role in the January 6 attack on the Capitol would have to address whether the First Amendment protects the inflammatory remarks he made at the “Stop the Steal” rally. A prosecution based solely on the content of Trump’s speech—whether for incitement, insurrection, or obstruction—would face serious constitutional difficulties under Brandenburg v. Ohio’s dual requirements of intent and likely imminence. But a prosecution need not rely solely on the content of Trump’s speech. It can also look to Trump’s actions: his order to the remove the magnetometers from the entrances to the rally and …
Overcoming The Peremptory's Greatest Challenge, Brian A. Wilson
Overcoming The Peremptory's Greatest Challenge, Brian A. Wilson
Faculty Scholarship
Four decades after the Supreme Judicial Court ("SJC") first proscribed certain group-based peremptory challenges, eradicating unlawful discrimination in jury selection has gained renewed interest. Yet so long as Massachusetts retains the inherently flawed three-step "Batson-Soares" test, lawyers seeking to exclude jurors for impermissible reasons will proceed virtually undeterred.
The solution is not to abolish peremptory challenges, as Arizona did in 2022. When exercised lawfully, they enable litigants to remove jurors they legitimately perceive as biased where a challenge for cause, due to its narrow scope, legally cannot. Eliminating peremptories would provide the parties little opportunity to influence who decides the …
Exegetical Analysis Paper: An Examination Of 1 Corinthians 11:27-29, Keegan Matheson
Exegetical Analysis Paper: An Examination Of 1 Corinthians 11:27-29, Keegan Matheson
Biblical Studies Student Projects
The paper is an exegetical analysis on 1 Corinthians 11:27-29. It offers several interpretative options of the phrase "discerning the body" which is found in verse 29 (ESV). The goal of this paper is to examine the different interpretative options of the phrase and decide which interpretation makes the most sense within the context of Pauline theology.
Berbamine Enhances The Efficacy Of Doxorubicin Treatment For Breast Cancer In Vitro And In Vivo, Kristina G. Borglum
Berbamine Enhances The Efficacy Of Doxorubicin Treatment For Breast Cancer In Vitro And In Vivo, Kristina G. Borglum
Senior Theses
Doxorubicin (Dox) is a commonly used chemotherapy drug for treating breast cancer. While it is very effective, the main limitation of Dox treatment is subsequent cytotoxicity. Berbamine dihydrochloride (BBM) is a natural benzylisoquinoline alkaloid that is extracted from the plant, Berbaris amurensis. It has been widely used in traditional medicine to treat individuals with inflammatory diseases for many centuries. It has already been shown that combining BBM with Dox synergistically enhances the efficacy of Dox treatment on breast cancer in vitro. To eventually translate these findings into a clinical setting, this study aims to explore this therapeutic potential in vivo …
Converting Hydrazone-Based Photoswitches Into Functional Materials, Sirun Yang
Converting Hydrazone-Based Photoswitches Into Functional Materials, Sirun Yang
Dartmouth College Ph.D Dissertations
The development of new classes of molecular switches with enhanced performance and brand-new functionalities enables practitioners to push the frontiers of adaptive materials. In the realm of photoswitches, the bistability of hydrazones (i.e., molecules that incorporate the C=N-NH functional group) allows for the kinetic trapping of polymer and supramolecular assemblies resulting in multistate actuation and emergent phenomena that are not tractable with other photoswitches. This property has transformed hydrazone photoswitches into powerful tools that can be used in understanding fundamental molecular interactions and how to apply them in modulating the physicochemical properties of materials.
Progressing from disordered to …
The Frog Sign Revisited, Christopher J. Ho, Reginald T. Ho
The Frog Sign Revisited, Christopher J. Ho, Reginald T. Ho
Division of Cardiology Faculty Papers
The frog sign is a classic physical examination finding of typical atrioventricular nodal re-entrant tachycardia. We present the case of a 78-year-old man with recurrent, symptomatic supraventricular tachycardia referred for ablation in whom the frog sign was observed during physical examination.
Atrial Fibrillation Induced By Anticancer Drugs And Underling Mechanisms., Alexander Burashnikov
Atrial Fibrillation Induced By Anticancer Drugs And Underling Mechanisms., Alexander Burashnikov
Division of Cardiology Faculty Papers
Cancer therapy has made major progress in the past several decades, but treatments are often accompanied by significant side effects. Arrhythmias are a widespread complication of some antineoplastic drugs, with atrial fibrillation (AF) being the most often encountered drug-associated arrhythmia. Preexisting AF risk factors are commonly present in cancer patients who develop drug-associated AF, and active cancer itself may cause or promote AF. Although anticancer drugs may induce AF in cancer patients without AF risk factors, it appears that most drug-associated AF develop when cancer drugs add or aggravate precancer-existing and/or cancer-related pro-AF factors/alterations, additively or synergistically producing AF. Abnormalities …
Preservation Technology Investment And Carbon Abatement Strategies In A Supplier-Retailer Cold Chain Based On A Differential Game, Xueli Ma, Ying Zhao, Qian Luo, Qingguo Bai
Preservation Technology Investment And Carbon Abatement Strategies In A Supplier-Retailer Cold Chain Based On A Differential Game, Xueli Ma, Ying Zhao, Qian Luo, Qingguo Bai
Research Collection Lee Kong Chian School Of Business
Against the background of a low-carbon economy and the rising environmental awareness, extensive attention has been paid to carbon emissions in the cold chain in academic research and practice. In cold chain operations, consumers’ preference for freshness is also growing, which motivates the investment in preservation technology to improve the freshness of perishable products. However, further investment in preservation technology also increases carbon emissions. Considering these idiosyncratic features in cold chains, we apply a differential game model to examine cold chain members’ preservation technology investment and carbon abatement behaviors from a long-term horizon and dynamic perspective. The equilibrium strategies of …
Commonality In Credit Spread Changes: Dealer Inventory And Intermediary Distress, Zhiguo He, Paymon Khorrami, Zhaogang Song
Commonality In Credit Spread Changes: Dealer Inventory And Intermediary Distress, Zhiguo He, Paymon Khorrami, Zhaogang Song
Research Collection Lee Kong Chian School Of Business
Two intermediary-based factors—a corporate bond dealer inventory measure and a broad intermediary distress measure—explain more than 40% of the puzzling common variation in credit spread changes beyond canonical structural factors. A simple intermediary-based model with partial market segmentation accounts for intermediary factors’ explanatory power and delivers three further implications with empirical support. First, whereas bond sorts on risk-related variables produce monotonic loading patterns on intermediary factors, non-risk-related sorts produce no pattern. Second, dealer inventory comoves with corporate-credit assets only, whereas intermediary distress comoves with both corporate-credit and non-corporate-credit assets. Third, dealers’ inventory responds to (instrumented) bond sales by institutional investors.
Smokejumper Magazine, October 2022, National Smokejumper Association
Smokejumper Magazine, October 2022, National Smokejumper Association
Smokejumper and Static Line Magazines
Alex Coolidge Wrestling Champ; Remembering Francis B. "Pappy" Lufkin; Forest Fires and National Defense Policy (2021); "Ve get too soon old, und too late schmart." Letter from Ron Pond; A View of the Largest Wildfi re in the History of New Mexico; Odds and Ends; Wheels Off; Mitch’s Last Jump; Seventy-Seven Years Ago in Smokejumper History; Recording Smokejumper History; 1947 Rookies—The Post WWII Era; NSA History Preservation Project; The Four Texan Fire; Not Forgotten; Final Request; Farewell to "Animal" Ed Weissenback; Getting Old; Sounding Off from the Editor; Doug Houston Memorial; The Jump List, Men of 1955; Mess Hall Crisis—Fairbanks …
“Nothing To Do But Be Borne And Steered”: Unpacking Feminist Scripts In Elana Arnold’S Damsel, Jenna Spiering, Nicole Ann Amato
“Nothing To Do But Be Borne And Steered”: Unpacking Feminist Scripts In Elana Arnold’S Damsel, Jenna Spiering, Nicole Ann Amato
Faculty Publications
Feminism in novels marketed for young adults often reflects the values of a popular feminism that relies on individual and personal means of empowerment, rather than critiquing or seeking to dismantle systems of domination. In this paper, we illumminate frameworks and methods for engaging students in careful readings and evaluations of texts marketed as feminist, through an analysis of Elana Arnold’s feminist fairy tale, Damsel (2018). Drawing on theoretical frameworks of popular feminism, feral feminism, and theories of becoming, the authors use Critical Content Anlaysis to explore several tenets in contemporary feminist thought in order to analyze Arnold’s text and …