Digital Commons Network^™

Immersion In Hot Water As A Phytosanitary Treatment For Thaumatotibia Leucotreta (Lepidoptera: Tortricidae) In Bell Pepper (Capsicum Annuum L.), Nelson L. Mwando, Shepard Ndlela, Rainer Meyhöfer, Sevgan Subramanian, Samira A. Mohamed

All Peer-Reviewed Publications

The False codling moth (FCM), Thaumatotibia leucotreta is a major quarantine pest that hampers Capsicum production and trade in sub-Saharan Africa (SSA) and may need a postharvest treatment to meet quarantine standards of lucrative overseas markets. In this study, we evaluated the efficacy of hot water treatment (HWT) as a potential nonchemical quarantine control option against T. leucotreta in bell pepper and its effect on the quality parameters of the peppers. Infested bell pepper harboring different immature stages of T. leucotreta were subjected to a hot water treatment of 50 ± 0.2 °C for eight different time-points to determine heat …

Engaging And Mobilizing Baby Boomers For Effective Ministry, Paul D. Russell

Doctor of Ministry (DMin)

In the 21st-century church in America, can Baby Boomers, who presently range from 57 to 76 years of age, be envisioned and commissioned to make a difference through effective and meaningful ministry? The intent of the research was to discover relevant information and present considerations to help those entering the last third of life make an informed contribution to the church and community. Evidence will be presented to show that Boomers need the church and that the church needs the presence and resourceful productivity of the Boomer cohort. This reality does not circumvent the essential mission of reaching other generations …

Horror: Where Are We? Where Do We Go?, Branden Boehnke

Theses

This project will investigate the current production standards, inspiration and evolution of the genre of horror in media. The final deliverable is a 30 minute documentary covering the genre as a whole across different forms of media. The documentary also includes interviews of respected figures within the genre from different aspects of media such as film, video games, viral social media posts and online databases.

Demographics And Baseline Disease Characteristics Of Patients With Relapsing Multiple Sclerosis From Kenya Participating In The Chimes Trial, Dilraj Sokhi, Juzar Hooker, Mitzi J. Williams, Aisleen Shamshudin, Yuashita Hussein, Peter Betti, Heldah Amariati, Noureen Karimi, Stacey Gondi, Mansoor Saleh

Book Chapters / Conference Papers

No abstract provided.

Exploring The Dynamics Of Primary Epsteinbarr Virus Infection Using A Novel Rabbit, Narendran Reguraman

Dissertations

Epstein-Barr virus (EBV) is a common herpesvirus asymptomatically carried by over 90% of the world population. However, in certain circumstances, the virus can lead to life-threatening diseases. Although the virus was isolated over 55 years ago, several fundamental aspects of the biology of EBV and the mechanism by which this virus induces pathology remain unknown. One major obstacle has been the lack of a suitable small animal model for EBV infection. We have recently shown that healthy rabbits are susceptible to EBV infection, and the virus establishes long-term latent infection typically seen in humans. The main objective of this dissertation …

Data Management Report October 2022, Tennessee. Department Of Intellectual And Developmental Disabilities

Compliance & System Data/Reports

This monthly report provides data on various aspects of the department's activities and programs.

Non-Satisfaction Of Pre-Arbitration Requirements: Moving Away From Conditions Precedent Towards The Admissibility Of A Claim – Nwa V Nvf, Darius Chan, Joel Soon

Research Collection Yong Pung How School Of Law

In earlier cases, the non-satisfaction of pre-arbitration requirements has been analysed by the Singapore and English courts by reference to the issue of conditions precedent. It was assumed without argument that, if a requirement was construed as a condition precedent, the failure to satisfy that requirement would deprive the tribunal of jurisdiction. More recently, English and Hong Kong case law has focused on a different issue, asking whether the failure to meet the pre-arbitration requirement affects the tribunal’s jurisdiction or the admissibility of the claim. This case note analyses whether the Singapore courts should follow suit.

Making Singapore A Regional Centre For Philanthropy, Kim Kit Ow, Vincent Ooi

Research Collection Yong Pung How School Of Law

The article highlights the strong ecosystem in Singapore where charitable initiatives are supported and encouraged, and builds on DPM Lawrence Wong's recent comments that the Government is reviewing its tax incentive schemes to encourage increased philanthropic giving.As a starting point, we suggest three simple ways in which tax incentives could be enhanced:1) increasing the enhanced tax deduction for donations from the current 2.5 times the amount of qualifying donations to 3 times for certain causes where there is a significant amount of public spending;2) extending the period for which tax deductions for donations can be carried forward for from the …

Promoting Constitutional Literacy: What Role For Courts?, De Maartje Visser

Research Collection Yong Pung How School Of Law

This article explores the role of constitutional judges in advancing constitutional literacy, understood as knowledge relating to the functioning of the constitutional order. Part of the inquiry is descriptive and geared towards identifying the modalities that courts today use to cultivate such literacy among the public, or segments thereof. The article also poses normative questions about literacy-boosting efforts. How do these relate to typical judicial functions? Are courts well-placed and equipped to disseminate constitutional knowledge? Based on an analysis of judicial practices, it is suggested that lay individuals are increasingly treated as a key constituency by courts, warranting the development …

When Tensions Become Opportunities: Managing Accountability Demands In Collaborative Governance, Seulki Lee

Research Collection School of Social Sciences

Accountability in collaborative governance comprises a tangled web of vertical and horizontal accountability relationships. While different accountability mechanisms are apparently complementary, they also clash with each other, producing serious accountability tensions. This study explores how actors in collaborative governance experience and manage conflicting accountability demands in the context of a Korean interorganizational network. Using qualitative data based on in-depth interviews with 32 personnel across 10 organizations and document analysis, the study identifies different types of accountability tensions and actors’ strategic responses to them. The analysis reveals that accountability tensions vary across the sources of the demand, and they are more …

Regulating Auditing Algorithms: An Asian Solution?, Nydia Remolina Leon

Research Collection Yong Pung How School Of Law

As AI becomes more sophisticated and broadly used, algorithmic auditing also involves increasingly complicated ethical, social, and regulatory challenges with different dimensions and implications depending on the sector where the AI is deployed. In this context, regulators play a key role in proposing policies to govern the operations, credentials, and impact of the experts conducting AI audits.

The Future Of Digital Justice, Dirk Hartung, Florian Brunnader, Christian Veith, Philipp Plog, Tim Wolters

Research Collection Yong Pung How School Of Law

Justice systems worldwide are under increasing pressure as legal complexity rises andmore people rightfully demand access to justice. Digital transformation is the key forcourts to keep pace. Digital justice is an immense chance to improve the lives ofmillions of people, but only if the technology is understood and implemented fast.Drivers of Digital JusticeGlobally, the digitalization of justice systems is just beginning and generally laggingbehind the digital transformation of the rest of society. This has led to a widening gapbetween the expected user experience for both consumers and businesses and theactual services provided by the courts.Status quo of Digital Justice TransformationThe …

Geopolitical Geometries In China-Russia Relations, William A. Callahan

Research Collection School of Social Sciences

Strategists in Beijing tend to think of geopolitics in terms of geometries, especially strategic triangles and the concentric circles of tianxia (“all under heaven”).China’s strategic triangles should be understood as United Front Work, which are intended to join with one group of ‘friends’ to isolate and attack another group of ‘enemies’.Both China and Russia present their own models of global concentric circles. Here China and Russia are each at the centre of their own world orders, and each is at the periphery of the other’s, which eventually will lead to conflict.

Relationship Between Preexisting Cardiovascular Disease And Death And Cardiovascular Outcomes In Critically Ill Patients With Covid-19, Tonimarie Catalan, Patrick O'Hayer, Kishan Padalia, Pennelope Blakely, Ibrahim Khaleel, Erinleigh Michaud, Yiyuan Huang, Lili Zhao, Rodica Pop-Busui, Shruti Gupta, Kim Eagle, David E Leaf, Salim S Hayek

Faculty, Staff and Student Publications

BACKGROUND: Preexisting cardiovascular disease (CVD) is perceived as a risk factor for poor outcomes in patients with COVID-19. We sought to determine whether CVD is associated with in-hospital death and cardiovascular events in critically ill patients with COVID-19.

METHODS: This study used data from a multicenter cohort of adults with laboratory-confirmed COVID-19 admitted to intensive care units at 68 centers across the United States from March 1 to July 1, 2020. The primary exposure was CVD, defined as preexisting coronary artery disease, congestive heart failure, or atrial fibrillation/flutter. Myocardial injury on intensive care unit admission defined as a troponin I …

Early Versus Delayed Treatment With Glatiramer Acetate: Analysis Of Up To 27 Years Of Continuous Follow-Up In A Us Open-Label Extension Study, Robert P Lisak, Horea Rus, Jerry S Wolinsky, Shaul E Kadosh, Emily Bernstein-Hanlon, Yafit Stark, Jessica K Alexander

Faculty, Staff and Student Publications

BACKGROUND: Glatiramer acetate (GA) is US-approved for relapsing multiple sclerosis.

OBJECTIVES: To describe GA long-term clinical profile. To compare effectiveness of early start (ES) versus delayed start (DS; up to 3 years) with GA.

METHODS: Phase 3 trial participants entered a randomized placebo-controlled period then an open-label extension (OLE) with GA.

RESULTS: Overall, 208 out of 251 (82.9%) randomized participants entered the OLE; 24 out of 101 (23.8%, ES) and 28 out of 107 (26.2%, DS) participants completed the OLE. Median GA treatment was 9.8 (0.1-26.3) years. Annualized change in Expanded Disability Status Scale (EDSS) score was lower with ES …

Aerosol Production With Surgical Instrumentation: Implications For Head And Neck Surgery In The Covid-19 Era, Ron J Karni

Faculty, Staff and Student Publications

Evaluating the aerosolization of droplets from surgical instruments to assess the implications of surgery in SARS-CoV-2 transmission for both patients and providers. Cadaver study. Outpatient surgery center. Aerosolized particles between 0.3 and 25 microns were measured. Instruments tested included monopolar cautery with and without suction, bipolar cautery, a bipolar vessel sealing device, and tissue scissors. Each trial was compared to a background reading. Monopolar cautery without suction, Ligasure used continuously and Bipolar cautery produced the most aerosols. Monopolar cautery with simultaneous suction produced no detectable aerosols. Ligasure used for a single cycle produced notably fewer aerosols than during continuous use. …

Ocrelizumab Reduces Thalamic Volume Loss In Patients With Rms And Ppms, Ludwig Kappos, Johan Van Beek, Harold Koendgen, Oscar Bortolami, Corrado Bernasconi, Laura Gaetano, Anthony Traboulsee

Faculty, Staff and Student Publications

Background: In multiple sclerosis (MS), thalamic integrity is affected directly by demyelination and neuronal loss, and indirectly by gray/white matter lesions outside the thalamus, altering thalamic neuronal projections.

Objective: To assess the efficacy of ocrelizumab compared with interferon beta-1a (IFNβ1a)/placebo on thalamic volume loss and the effect of switching to ocrelizumab on volume change in the Phase III trials in relapsing MS (RMS, OPERA I/II; NCT01247324/NCT01412333) and in primary progressive MS (PPMS, ORATORIO; NCT01194570).

Methods: Thalamic volume change was computed using paired Jacobian integration and analyzed using an adjusted mixed-effects repeated measurement model.

Results: Over the double-blind period, …

Design And Fabrication Of A Low-Cost And Programmable Dip Coating Machine, Christy Dunlap, Skylar Featherstone, Matthew Smith, Man Vu, Amanda Williams, Jason Bailey, Han Hu

Mechanical Engineering Faculty Publications and Presentations

Dip coaters provide a compact device that can be used to obtain uniform and consistent coatings on a substrate. This article describes a less costly dip coater design with similar specifications to other dip coaters. The machine consists of a NEMA 23 stepper motor, touch screen display, and acrylic housing to protect the substrate from dust. The machine is programmed using Arduino IDE, allowing for easy changes to be made. The small size of the dip coater makes it ideal for use in labs. The majority of the components require no alterations after purchase, allowing for easy replacements and construction.

Two Cases Of Autoimmune Syndrome Induced By Adjuvants (Asia): A Multifaceted Condition Calling For A Multidisciplinary Approach, Christine Loftis, Aidee C. Nunez, Mauricio De La Garza, Emilia Dulgheru

School of Medicine Publications

Silicone implants have been used for cosmetic enhancement and reconstructive purposes for over 60 years. Despite assiduous efforts to ensure safety, there is continuous evidence that they are not as biologically inert as previously postulated. We present two cases of autoimmune syndrome induced by adjuvants (ASIA) in Hispanic women. The first patient developed biopsy-proven immune-mediated necrotizing myopathy that was successfully treated with the combination of silicone explantation along with immunosuppressive therapy. Findings after implant removal demonstrated rupture and leakage of silicone from gluteal implants. The second patient developed autoimmune hemolytic anemia in the setting of a ruptured silicone breast implant. …

Neoadjuvant Atezolizumab For Resectable Non-Small Cell Lung Cancer: An Open-Label, Single-Arm Phase Ii Trial, Jamie E Chaft, G Alexander Patterson, Saiama N Waqar, Et Al.

2020-Current year OA Pubs

In an ongoing, open-label, single-arm phase II study ( NCT02927301 ), 181 patients with untreated, resectable, stage IB-IIIB non-small cell lung cancer received two doses of neoadjuvant atezolizumab monotherapy. The primary end point was major pathological response (MPR; ≤10% viable malignant cells) in resected tumors without EGFR or ALK alterations. Of the 143 patients in the primary end point analysis, the MPR was 20% (95% confidence interval, 14-28%). With a minimum duration of follow-up of 3 years, the 3-year survival rate of 80% was encouraging. The most common adverse events during the neoadjuvant phase were fatigue (39%, 71 of 181) …

Congenital Aneurysm Of The Muscular Interventricular Septum Associated With Bifascicular Block, Hoang H. Nguyen, Patrick Y. Jay

2020-Current year OA Pubs

Isolated congenital aneurysm of the muscular interventricular septum is rare. We present a patient with congenital aneurysm of the basal muscular ventricular septum, who also develops conduction abnormalities with first-degree heart block, right bundle branch block, and left posterior fascicular block. The case details the natural history of the aneurysm over a 10-year period follow-up during which the patient remained asymptomatic with evidence of regression of the aneurysm. Given the aneurysm's location close to the proximal right bundle and left posterior fascicle, we believe that the cause for the aneurysm also injured both fascicles resulting in bifascicular block. The diagnosis …

Social Justice Reads Mini Zine, Jessica Kiebler, Jennifer Rosenstein

Social Justice Week

This zine was created to accompany the event Social Justice Reads, held at both the NYC and PLV campus libraries on October 28, 2022.

This zine has information about: issues of social justice related to information literacy & access definitions & descriptions of the issues, as well as links to resources to learn more.

Colorblind Capture, Jonathan Feingold

Faculty Scholarship

We are facing two converging waves of racial retrenchment. The first, which arose following the Civil Rights Movement, is nearing a legal milestone. This term or the next, the Supreme Court will prohibit affirmative action in higher education. When it does, the Court will cement decades of conservative jurisprudence that has systematically eroded the right to remedy racial inequality.

The second wave is more recent but no less significant. Following 2020’s global uprising for racial justice, rightwing forces launched a coordinated assault on antiracism itself. The campaign has enjoyed early success. As one measure, GOP officials have passed, proposed or …

Poly Under Pandemic: A Pilot Survey Examining Cal Poly Slo’S Student Body During The Covid-19 Pandemic, Brett Vollrath

Journalism

The following is a survey of Cal Poly SLO students and alumni who had attended the university while major pandemic restrictions were in place. The paper is based around a pilot survey and data set.

The introduction provides background on the problem and how this survey was prepared.

The literature review details research conducted during the pandemic, which was used to guide the survey's focus questions.

The survey section details the questions asked of respondents. Respondents were first asked demographic questions to establish reference points. They were then asked questions on different aspects of student life, such as mental health, …

Exploring The Experiences Of Runners With Visual Impairments And Sighted Guides, Lindsay E. Ball, Lauren J. Leiberman, Pamela Beach, Melanie Perreault, Jason Rich

Human Movement Studies & Special Education Faculty Publications

: Running is a popular sport, and, with simple modifications, it can be accessible for individuals with visual impairments, particularly with a sighted running guide. The purpose of this study is to examine the experiences of runners with visual impairments and sighted running guides. Adopting a descriptive qualitative approach to guide data collection analysis and interpretation, seven runners with visual impairments and four sighted running guides were recruited and interviewed. The analysis identified four major themes: (1) benefits, (2) barriers, (3) advocacy, and (4) communication. The identified themes illustrate the influence of participation in running on the health and relationships …

Equivocal Originalism, Gary S. Lawson

Faculty Scholarship

"Originalism" is a term shrouded in ambiguity and ripe for equivocation. A recent article by Stephen Sachs in the Harvard Law Review tries to clarify the discussion by distinguishing between originalism as a decision standard, or a set of criteria for ascertaining the truth conditions for propositions, and a decision procedure, or a mechanism for ascertaining whether those truth conditions are satisfied in any given context. That is a helpful distinction, but it still leaves much room for multiple and confusing uses of the term originalism. Jumping off from comments on Professor Sachs's article by Mitchell Berman and Judge Andrew …

Green, Or Greed? A Fresh Perspective On The Valuation Of Conservation Easements, Alan L. Feld, Jacob Nielson, Theodore S. Sims

Faculty Scholarship

Charitable contributions of "conservation easements" have since 1980 allowed high-income taxpayers to shelter income from taxation through overvalued deductions. Overvaluation has increased dramatically in the past 20 years: a 2016 study of all easement decisions since 1980 reported that while overvaluation had averaged by a factor of two before 1994, it averaged by a factor of ten for decisions between 1994 and 2016. SOI data disclose that aggregate easement contributions deducted on Schedule A grew from $2.26 billion in 2015 to $6.5 billion in 2018 (the most recent year available). A recent report by supporters of conservation easements acknowledges that …

Functionality Of The Gracilis Collateral Is Impaired Following Arteriogenesis And Cell Transplantation, Ada A. Tadeo

Biomedical Engineering

Peripheral Arterial Disease involves narrowed arteries, reducing blood flow to limbs. Increasing blood flow to those extremities is possible by redirecting the blood to flow through natural bypasses (i.e. collateral arteries), which can enlarge via arteriogenesis to maintain blood supply once the prominent arteries have become occluded. This study aims to investigate how arteriogenesis affects collateral function, if myoblast transplantation can stimulate collateral growth, and how that in turn may affect collateral function. Femoral artery ligation was performed to mimic the blockage that occurs in patients with ischemic diseases on lean mice and mice with diet induced obesity (DIO). A …

Telomere Biology Disorders: Time For Moving Towards The Clinic?, Luis F Z Batista, Inderjeet Dokal, Roy Parker

2020-Current year OA Pubs

Telomere biology disorders (TBDs) are a group of rare diseases caused by mutations that impair telomere maintenance. Mutations that cause reduced levels of TERC/hTR, the telomerase RNA component, are found in most TBD patients and include loss-of-function mutations in hTR itself, in hTR-binding proteins [NOP10, NHP2, NAF1, ZCCHC8, and dyskerin (DKC1)], and in proteins required for hTR processing (PARN). These patients show diverse clinical presentations that most commonly include bone marrow failure (BMF)/aplastic anemia (AA), pulmonary fibrosis, and liver cirrhosis. There are no curative therapies for TBD patients. An understanding of hTR biogenesis, maturation, and degradation has identified pathways and …

Antimicrobial Stewardship For Sepsis In The Intensive Care Unit: Survey Of Critical Care And Infectious Diseases Physicians, M Cristina Vazquez Guillamet, Jason P Burnham, Maria Pérez, Marin H Kollef, Constantine A Manthous, Donna B Jeffe

2020-Current year OA Pubs

OBJECTIVE: To evaluate the attitudes of infectious diseases (ID) and critical care physicians toward antimicrobial stewardship in the intensive care unit (ICU).

DESIGN: Anonymous, cross-sectional, web-based surveys.

SETTING: Surveys were completed in March-November 2017, and data were analyzed from December 2017 to December 2019.

PARTICIPANTS: ID and critical care fellows and attending physicians.

METHODS: We included 10 demographic and 17 newly developed, 5-point, Likert-scaled items measuring attitudes toward ICU antimicrobial stewardship and transdisciplinary collaboration. Exploratory principal components analysis (PCA) was used for data reduction. Multivariable linear regression models explored demographic and attitudinal variables.

RESULTS: Of 372 respondents, 315 physicians had …