Digital Commons Network^™

Just What "Doc" Ordered, Tori Miller

Materials from the University of Dayton Magazine Website

From one Catholic school to another, how a high school guidance counselor has helped recruit University of Dayton students for years.

70 Years Of Dance: Copyrighting Choreography Since 1952, Annie Planker

Cardozo Arts & Entertainment Law Journal (AELJ) Blog

Choreography has long been a subject of controversy in the world of copyright. Despite its significance in the artistic community and the rise of social media in our everyday lives, choreography has not received the same property protections as other artforms, such as music, painting or sculpture. This is partly due to the transient nature of choreography; copyright law requires “fixed expressions” of works. It is also due to a legal hesitation to limit “social” arts. Lawmakers have little desire to prohibit large masses from participating in cultural activities.

This post was originally published on the Cardozo Arts & Entertainment …

Chronic Red Cell Exchange In Sickle Cell Patients With Iron Overload May Not Affect Mortality, Yi Yuan Zhou, Hollie M. Reeves, Robert W. Maitta

Faculty Scholarship

Sickle cell disease (SCD) is an inherited blood disorder that affects ~100,000 Americans (1, 2). In SCD, red blood cells (RBC) containing aberrant sickle hemoglobin (HgbS) become sickle-shaped at low oxygen tension and stick together leading to obstructed blood flow. The resulting decrease in tissue oxygenation causes chronic complications such as vasculo-occlusive pain crises among others that require frequent hospitalizations (3). Chronic RBC transfusions play a prominent role in the treatment of this disease by improving oxygenation through addition of normal RBC and dilution of RBC containing HgbS (4, 5). However, the major disadvantage of management with simple transfusion is …

Eastern White Pine Symposium: Management Trends, William H. Livingston

UNH Cooperative Extension

No abstract provided.

Comparative Study Of High-Performance Thin-Layer Chromatography And Antioxidant Potential Of Hydrocotyle Asiatica Mother Tincture Used In Homoeopathy, Rakhi Mishra, Binit Kumar Dwivedi, Deepshikha Gupta

Indian Journal of Research in Homoeopathy

Background: Hydrocotyle asiatica has a therapeutic significance in the Indian system of medicine due to its rich antioxidant activity. In Homoeopathy, Hydrocotyle asiatica is used for the treatment of jaundice, skin diseases, dropsy, elephantiasis, leprosy, gonorrhea, leucorrhea, and nervous debility. It contains the abundant triterpene glycoside Asiatic acid which shows cytotoxic activity on cancer cells. Its homoeopathic mother tincture is a major source of antioxidant compounds, which is responsible for its overall pharmacological activity.

Objectives: This study was done to evaluate antioxidant activity and High-Performance Thin-Layer Chromatography study of Hydrocotyle asiatica in-house homoeopathic mother tincture and market samples. …

Cholesterol Lowering Activity Of Homoeopathic Preparations Of Colchicum Autumnale – An In Vitro Study, Nithya T, Mansoor Ali Kr, Sheeba Veluthoor, U S Jijith, P Sithara Perveen, Afiya Alloor, Shijil V K

Indian Journal of Research in Homoeopathy

Background: Total cholesterol content of erythrocyte membranes plays a critical role in atherosclerotic plaque progression and instability. Several homoeopathic medicines are known to have a significant role in the control of hyperlipidaemia. Colchicum autumnale is a plant remedy used mainly for gout, but also for hyperlipidaemia.

Objectives: This is a study to assess the in vitro anti-cholesterol action of the Colchicum autumnale (Colch. at.) on the erythrocyte membrane. Materials and

Methods: The study was conducted using a hyperlipidaemic blood sample which was divided into eight parts. Six different potencies of Colch. at. were tested, and two controls, …

Homoeopathy In The Management Of Chronic Kidney Disease – A Narrative Review, Supriya Singh, Varanasi Roja, Khushboo Garg, Nisha Sehrawat, Jyotika Bhatti, Abhijit Chakma

Indian Journal of Research in Homoeopathy

Background: Chronic kidney disease (CKD) is the third fastest-growing cause of death around the world and is projected to become the fifth most common cause of years of life lost worldwide by 2040.

Objective: This review was done to explore the strengths of homoeopathy in the management of CKD through pre-clinical, clinical and anecdotal evidence.

Methods: A search was made for homoeopathic management of CKD in PubMed, Central Council for Research in Homoeopathy e-library, AYUSH Research Portal, EMBASE and Google Scholar. The basic search terms included ‘Homoeopathy’ or ‘homoeopathic drugs’, ‘ESRD’, ‘CRF’, ‘CKD’ and ‘Bright’s disease’. No …

Nephrotic Syndrome Treated With Homoeopathy: An Evidence-Based Case-Report, Punam Kumari, Renu Verma

Indian Journal of Research in Homoeopathy

Introduction: Nephrotic syndrome (NS) is a glomerular disorder characterised by peripheral oedema, heavy proteinuria and hypoalbuminemia, often hyperlipidaemia. Patients generally present with oedema and fatigue. Complementary and alternative therapies have been widely used in the treatment of NS. The homoeopathic treatment for NS could be a safer approach to treating the disease.

Case Summary: This is the case of a 32-year-old man who presented with NS with membranous nephropathy and was successfully managed with individualised homoeopathic medicine, Natrium Sulphuricum over 1 year. The case was followed up with documentation of clinical symptoms and investigation reports findings. Changes in …

Polycystic Ovarian Syndrome With Endometrial Hyperplasia And Uterine Fibroids Treated With Homoeopathy: A Case Report, Vaishali Shinde

Indian Journal of Research in Homoeopathy

Introduction: Any circumstance that alters the balance of oestrogen and progesterone leads to excessive, prolonged estrogenic stimulation, or preventing the counteracting effects of progesterone causing various pathological conditions in the reproductive system, as a result. Women with polycystic ovarian syndrome (PCOS) have mostly anovulatory cycles and low serum progesterone levels. Endometrial hyperplasia is most often due to excess oestrogen without progesterone. The clinical significance of chronic oestrogen secretion is an increased risk of endometrial hyperplasia. A striking feature of uterine fibroids (UFs) is their dependency on the ovarian oestrogen and progesterone. Existing treatments are mostly directed at the symptoms …

Obituary : Prof. Emeritus Dr. Girendra Pal, Subhash Kaushik, Praveen Oberai, Nidhi Mahajan, Chetna Deep Lamba

Indian Journal of Research in Homoeopathy

The death of legendary and philanthropist Homoeopath Dr. Girendra Pal which occurred in Jaipur on 24th August 2022, will be mourned by all Homoeopathic fraternity and his beloved patients, family and friends. He practiced and popularised homoeopathy in Rajasthan and is rightly known as Father of Homoeopathy in Rajasthan.

Research Highlights, Shweta Singh, Pooja Kumari

Indian Journal of Research in Homoeopathy

Research Highlights

Ampim V. 160 E. 48th St. Owner Ii Llc

All Decisions

No abstract provided.

Matter Of First Ny Llc V. New York State Div. Of Hous. & Community Renewal

All Decisions

No abstract provided.

Integration Of Mouse Ovary Morphogenesis With Developmental Dynamics Of The Oviduct, Ovarian Ligaments, And Rete Ovarii, Jennifer Mckey, Dilara N Anbarci, Corey Bunce, Alejandra E Ontiveros, Richard R Behringer, Blanche Capel

Faculty, Staff and Student Publications

Morphogenetic events during the development of the fetal ovary are crucial to the establishment of female fertility. However, the effects of structural rearrangements of the ovary and surrounding reproductive tissues on ovary morphogenesis remain largely uncharacterized. Using tissue clearing and lightsheet microscopy, we found that ovary folding correlated with regionalization into cortex and medulla. Relocation of the oviduct to the ventral aspect of the ovary led to ovary encapsulation, and mutual attachment of the ovary and oviduct to the cranial suspensory ligament likely triggered ovary folding. During this process, the rete ovarii (RO) elaborated into a convoluted tubular structure extending …

Molecular Pathways Enhance Drug Response Prediction Using Transfer Learning From Cell Lines To Tumors And Patient-Derived Xenografts, Yi-Ching Tang, Reid T Powell, Assaf Gottlieb

Faculty, Staff and Student Publications

Computational models have been successful in predicting drug sensitivity in cancer cell line data, creating an opportunity to guide precision medicine. However, translating these models to tumors remains challenging. We propose a new transfer learning workflow that transfers drug sensitivity predicting models from large-scale cancer cell lines to both tumors and patient derived xenografts based on molecular pathways derived from genomic features. We further compute feature importance to identify pathways most important to drug response prediction. We obtained good performance on tumors (AUROC = 0.77) and patient derived xenografts from triple negative breast cancers (RMSE = 0.11). Using feature importance, …

Non-Communicable Diseases: How Can Homoeopathy Contribute?, Subhash Kaushik

Indian Journal of Research in Homoeopathy

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Homoeopathic Management Of Polycystic Ovarian Syndrome – A Case Series, Sonia Raizada

Indian Journal of Research in Homoeopathy

Introduction: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in females of the reproductive age group. It is characterised by menstrual irregularities, enlarged ovaries, infertility, high levels of male hormones, excess hair on the face and body, acne and obesity. PCOS can result from abnormal function of the hypothalamic-pituitary-ovarian axis. Women with PCOS have an increased risk of diabetes, high blood pressure, heart disease and endometrial cancer.

Case Summary: A case series of seven PCOS patients treated with indicated constitutional homoeopathic medicines at Nehru Homoeopathic Medical College and Hospital, New Delhi, India, is presented here. Overall improvement …

The Lived Social Experience Of Covid-19 Survivors In Southwestern Nigeria, Endurance Uzobo, Ijeoma Nwanwene, Tolulope Funmilola Ojo

Journal of Social, Behavioral, and Health Sciences

The traditional perceptions of disease causation often reinforce the feelings of stigmatization and discrimination towards individuals who have recovered from an illness. This study investigated the existing social practices with regard to stigmatization and discrimination against COVID-19 survivors in Southwest Nigeria. Using the Psychoanalytic Theory, this phenomenological qualitative study utilized the snowball sampling method and an in-depth interview to sample 25 COVID-19 survivors in Southwest Nigeria. Collected data for this study were analyzed thematically, using content analysis with the aid of the ATLAS.ti software. Findings from the study indicated that COVID-19 survivors generally experience sympathy, hostility, mockery, and social exclusion. …

Recent Emergence Of Bovine Coronavirus Variants With Mutations In The Hemagglutinin-Esterase Receptor Binding Domain In U.S. Cattle, Aspen M. Workman, Tara G. Mcdaneld, Gregory P. Harhay, Subha Das, John Dustin Loy, Benjamin M. Hause

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine coronavirus (BCoV) has spilled over to many species, including humans, where the host range variant coronavirus OC43 is endemic. The balance of the opposing activities of the surface spike (S) and hemagglutinin-esterase (HE) glycoproteins controls BCoV avidity, which is critical for interspecies transmission and host adaptation. Here, 78 genomes were sequenced directly from clinical samples collected between 2013 and 2022 from cattle in 12 states, primarily in the Midwestern U.S. Relatively little genetic diversity was observed, with genomes having >98% nucleotide identity. Eleven isolates collected between 2020 and 2022 from four states (Nebraska, Colorado, California, and Wisconsin) contained a …

Access To Online Formative Assessments In Lower-Division Undergraduate Biology Courses: Investigating Barriers To Student Engagement, Allison M. Upchurch, Dana L. Kirkwood-Watts, Kathleen R. Brazeal, Lorey A. Wheeler, Brian A. Couch, Gabrielle B. Johnson, Sarah K. Spier

School of Biological Sciences: Faculty Publications

Instructors use a variety of online formative assessment (FA) activities to support learning outside class. Previous studies have revealed barriers for students in online courses, but little is known about the barriers students experience when completing online FA assignments. Understanding these barriers to access is critical to fostering more inclusive learning for all students. Using a framework from previous work in online learning, we examined student perceptions of online FA access with respect to five barrier categories: technical resources, instructor organization, social interactions, personal engagement, and learning environment. We developed and administered a survey to more than 1,200 undergraduate biology …

Design Of An Innovative Hybrid Sandwich Protective Device For Offshore Structures, Hozhabr Mozafari, Fabio Distefano, Gabriella Epasto, Linxia Gu, Emanoil Linul, Vincenzo Crupi

Department of Mechanical and Materials Engineering: Faculty Publications

Lightweight foam sandwich structures have excellent energy absorption capacity, combined with good mechanical properties and low density. The main goal of this study is to test the application of an innovative hybrid sandwich protective device in an offshore wind turbine (OWT). The results are useful for offshore structure applications. Different lightweight materials (aluminum foam, agglomerated cork, and polyurethane foam) were investigated using experimental tests and numerical simulations. Closed-cell aluminum foam showed the best performance in terms of the energy absorption capacity during an impact. As such, a Metallic Foam Shell (MFS) device was proposed for the fender of offshore wind …

Establishment Of Invasive Black Carp (Mylopharyngodon Piceus) In The Mississippi River Basin: Identifying Sources And Year Classes Contributing To Recruitment, Gregory W. Whitledge, Patrick T. Kroboth, Duane C. Chapman, Quinton E. Phelps, Wes Sleeper, Jennifer Bailey, Jill A. Jenkins

United States Geological Survey: Staff Publications

Black Carp (Mylopharyngodon piceus) was imported to the USA to control aquaculture pond snails. This species has escaped captivity and occurs in parts of the Mississippi River, several tributaries, and floodplain lakes, which is concerning due to potential competition with native fishes and predation on native mussels, many of which are imperiled. However, Black Carp captures have primarily been incidental by commercial fishers, and evidence of reproduction in the wild is limited. The objectives of this study were to assess relative abundance of aquaculture- origin and wild Black Carp using ploidy and otolith stable isotope analysis, identify spatial …

Enhanced Membrane Binding Of Oncogenic G Protein Αqq209l Confers Resistance To Inhibitor Ym-254890, Clinita E. Randolph, Morgan B. Dwyer, Jenna L. Aumiller, Alethia J. Dixon, Asuka Inoue, Patrick Osei-Owusu, Philip B. Wedegaertner

Department of Biochemistry and Molecular Biology Faculty Papers

Heterotrimeric G proteins couple activated G protein-coupled receptors (GPCRs) to intracellular signaling pathways. They can also function independently of GPCR activation upon acquiring mutations that prevent GTPase activity and result in constitutive signaling, as occurs with the αqQ209L mutation in uveal melanoma. YM-254890 (YM) can inhibit signaling by both GPCR-activated WT αq and GPCR-independent αqQ209L. Although YM inhibits WT αq by binding to αq-GDP and preventing GDP/GTP exchange, the mechanism of YM inhibition of cellular αqQ209L remains to be fully understood. Here, we show that YM promotes a subcellular redistribution of αqQ209L from the plasma membrane (PM) to the cytoplasm. …

Saturable Absorption Of Free-Electron Laser Radiation By Graphite Near The Carbon K-Edge, Lars Hoffman, Sasawat Jamnuch, Craig Schwartz, Tobias Helk, Sumana L. Raj, Hikaru Mizuno, Riccardo Mincigrucci, Laura Foglia, Emiliano Principi, Richard J. Saykally, Walkter S. Drisdell

Nevada Extreme Conditions Laboratory Faculty Research

The interaction of intense light with matter gives rise to competing nonlinear responses that can dynamically change material properties. Prominent examples are saturable absorption (SA) and two-photon absorption (TPA), which dynamically increase and decrease the transmission of a sample depending on pulse intensity, respectively. The availability of intense soft X-ray pulses from free-electron lasers (FELs) has led to observations of SA and TPA in separate experiments, leaving open questions about the possible interplay between and relative strength of the two phenomena. Here, we systematically study both phenomena in one experiment by exposing graphite films to soft X-ray FEL pulses of …

Recital: Convocation, September 27, 2022, Illinois State University School Of Music

School of Music Programs

Center for the Performing Arts
September 27, 2022
Tuesday Morning
11:00 a.m.

A Facile Synthetic Method For Anhydride From Carboxylic Acid With The Promotion Of Triphenylphosphine Oxide And Oxaloyl Chloride, Mengyu Lu, Huihui Fan, Qing Liu, Xiaoling Sun

Faculty, Staff and Student Publications

A highly efficient synthesis reaction of carboxylic anhydrides catalyzed by triphenylphosphine oxide is described for the quick synthesis of a range of symmetric carboxylic anhydrides and cyclic anhydrides under mild and neutral conditions with a high yield. The system adopts the strong reactive intermediate Ph3PCl2 as the catalyst of carboxylic acid salt; driven by catalytic reaction, the synthesis takes a relatively short time to complete.

Iwu Receives Grant To Grow Future Stem Education Workforce, Julia Perez

News and Events (Discontinued Series)

No abstract provided.

Local Bounds For Singular Brascamp–Lieb Forms With Cubical Structure, Polona Durcik, Lenka Slavíková, Chrisoph Thiele

Mathematics, Physics, and Computer Science Faculty Articles and Research

We prove a range of L^p bounds for singular Brascamp-Lieb forms with cubical structure. We pass through sparse and local bounds, the latter proved by an iteration of Fourier expansion, telescoping, and the Cauchy-Schwarz inequality. We allow 2^m−1 < p ≤ ∞ with m the dimension of the cube, extending an earlier result that required p = 2^m. The threshold 2^m−1 is sharp in our theorems.

Impad1 And Syt11 Work In An Epistatic Pathway That Regulates Emt-Mediated Vesicular Trafficking To Drive Lung Cancer Invasion And Metastasis, Rakhee Bajaj, B Leticia Rodriguez, William K Russell, Amanda N Warner, Lixia Diao, Jing Wang, Maria G Raso, Wei Lu, Khaja Khan, Luisa S Solis, Harsh Batra, Ximing Tang, Jared F Fradette, Samrat T Kundu, Don L Gibbons

Faculty, Staff and Student Publications

Lung cancer is a highly aggressive and metastatic disease responsible for approximately 25% of all cancer-related deaths in the United States. Using high-throughput in vitro and in vivo screens, we have previously established Impad1 as a driver of lung cancer invasion and metastasis. Here we elucidate that Impad1 is a direct target of the epithelial microRNAs (miRNAs) miR-200 and miR∼96 and is de-repressed during epithelial-to-mesenchymal transition (EMT); thus, we establish a mode of regulation of the protein. Impad1 modulates Golgi apparatus morphology and vesicular trafficking through its interaction with a trafficking protein, Syt11. These changes in Golgi apparatus dynamics alter …

The Effects Of Cannabidiol On Aqueous Humor Outflow And Trabecular Meshwork Cell Signaling., Alyssa S. Aebersold, Zhao-Hui Song

Faculty and Staff Scholarship

Intraocular pressure (IOP) is regulated primarily through aqueous humor production by ciliary body and drainage through uveoscleral and trabecular meshwork (TM) tissues. The goal of this study was to measure the effect of non-psychotropic cannabidiol (CBD) on aqueous humor outflow through TM and assess the effect of CBD on the TM cell signaling pathways that are important for regulating outflow. Perfused porcine eye anterior segment explants were used to investigate the effects of CBD on aqueous humor outflow. Cultured porcine TM cells were used to study the effects of CBD on TM cell contractility, myosin light chain (MLC) and myosin …