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Orthogonal Point Location And Rectangle Stabbing Queries In 3-D, Timothy M. Chan, Yakov Nekrich, Saladi Rahul, Konstantinos Tsakalidis Sep 2022

Orthogonal Point Location And Rectangle Stabbing Queries In 3-D, Timothy M. Chan, Yakov Nekrich, Saladi Rahul, Konstantinos Tsakalidis

Michigan Tech Publications, Part 1

In this work, we present a collection of new results on two fundamental problems in geometric data structures: orthogonal point location and rectangle stabbing.• Orthogonal point location. We give the first linear-space data structure that sup- ports 3-d point location queries on n disjoint axis-aligned boxes with optimal O (log") query time in the (arithmetic) pointer machine model. This improves the previous 0 (\ogi/2 n^ bound of Rahul \SODA 201o|. We similarly obtain the first linear-space data structure in the I/O model with optimal query cost, and also the first linear-space data structure in the word HAM model with sub-logarithmic …


Tauroursodeoxycholic Acid In Patients With Amyotrophic Lateral Sclerosis: The Tudca-Als Trial Protocol, Tudca-Als Study Group, Alberto Albanese, Albert Christian Ludolph, Christopher J. Mcdermott, Philippe Corcia, Philip Van Damme, Leonard H. Van Den Berg, Orla Hardiman, Gilberto Rinaldi, Nicola Vanacore, Brian Dickie, Paolo Tornese, Antoniangela Cocco, Maria Lo Giudice, Michela Matteoli, Eliana Lauranzano, Maria Luisa Malosio, Chiara Adriana Elia, Flavia Lombardo, Flavia Mayer, Maria Puopolo, Stefania Spila Alegiani, Adriano Chiò, Umberto Manera, Cristina Moglia, Andrea Calvo, Paolina Salamone, Giuseppe Fuda, Carlo Colosimo, Giuseppe Stipa, Domenico Frondizi, Christian Lunetta, Valeria Sansone, Claudia Tarlarini, Francesca Gerardi, Vincenzo Silani, Alberto Doretti, Eleonora Colombo, Gianluca Demirtzidis, Gioacchino Tedeschi, Francesca Trojsi, Carla Passaniti, Stefania Ballestrero, Johannes Dorst, Ulrike Weiland, Andrea Fromm, Maximilian Wiesenfarth, Katharina Kandler, Simon Witzel, Oliver Hanemann Sep 2022

Tauroursodeoxycholic Acid In Patients With Amyotrophic Lateral Sclerosis: The Tudca-Als Trial Protocol, Tudca-Als Study Group, Alberto Albanese, Albert Christian Ludolph, Christopher J. Mcdermott, Philippe Corcia, Philip Van Damme, Leonard H. Van Den Berg, Orla Hardiman, Gilberto Rinaldi, Nicola Vanacore, Brian Dickie, Paolo Tornese, Antoniangela Cocco, Maria Lo Giudice, Michela Matteoli, Eliana Lauranzano, Maria Luisa Malosio, Chiara Adriana Elia, Flavia Lombardo, Flavia Mayer, Maria Puopolo, Stefania Spila Alegiani, Adriano Chiò, Umberto Manera, Cristina Moglia, Andrea Calvo, Paolina Salamone, Giuseppe Fuda, Carlo Colosimo, Giuseppe Stipa, Domenico Frondizi, Christian Lunetta, Valeria Sansone, Claudia Tarlarini, Francesca Gerardi, Vincenzo Silani, Alberto Doretti, Eleonora Colombo, Gianluca Demirtzidis, Gioacchino Tedeschi, Francesca Trojsi, Carla Passaniti, Stefania Ballestrero, Johannes Dorst, Ulrike Weiland, Andrea Fromm, Maximilian Wiesenfarth, Katharina Kandler, Simon Witzel, Oliver Hanemann

Peninsula Medical School

Background: Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative rare disease that affects motor neurons in the brain, brainstem, and spinal cord, resulting in progressive weakness and atrophy of voluntary skeletal muscles. Although much has been achieved in understanding the disease pathogenesis, treatment options are limited, and in Europe, riluzole is the only approved drug. Recently, some other drugs showed minor effects. Methods: The TUDCA-ALS trial is a phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial. The study aims to enroll 320 patients in 25 centers across seven countries in Europe. Enrolled patients are randomized to one of two …


Contributor Notes, Oakwood Staff Sep 2022

Contributor Notes, Oakwood Staff

Oakwood

No abstract provided.


What Is Foolish, What Is Weak, Theodore Wheeler Sep 2022

What Is Foolish, What Is Weak, Theodore Wheeler

Oakwood

No abstract provided.


After Taking The Wrong I-480 Out Of Omaha, Joe Benevento Sep 2022

After Taking The Wrong I-480 Out Of Omaha, Joe Benevento

Oakwood

No abstract provided.


After Seeing My Son Dance A Tarantella In Fairfield, Iowa, Joe Benevento Sep 2022

After Seeing My Son Dance A Tarantella In Fairfield, Iowa, Joe Benevento

Oakwood

No abstract provided.


Threading A Needle, Lysbeth Em Benkert Sep 2022

Threading A Needle, Lysbeth Em Benkert

Oakwood

No abstract provided.


The Moon Sees Me, Lysbeth Em Benkert Sep 2022

The Moon Sees Me, Lysbeth Em Benkert

Oakwood

No abstract provided.


Over The Rainbow, Lysbeth Em Benkert Sep 2022

Over The Rainbow, Lysbeth Em Benkert

Oakwood

No abstract provided.


Three Hoots, Nothing More; Two Years Later, Cliff Taylor Sep 2022

Three Hoots, Nothing More; Two Years Later, Cliff Taylor

Oakwood

No abstract provided.


Cliff Senior; Myron, Cliff Taylor Sep 2022

Cliff Senior; Myron, Cliff Taylor

Oakwood

No abstract provided.


Still Standing, Mark Mcmillan Sep 2022

Still Standing, Mark Mcmillan

Oakwood

No abstract provided.


Shoveling, Nathaniel Lee Hansen Sep 2022

Shoveling, Nathaniel Lee Hansen

Oakwood

No abstract provided.


Call To Arms, Caitlin Irish Sep 2022

Call To Arms, Caitlin Irish

Oakwood

No abstract provided.


Mental Health, Lin Marshall Brummels Sep 2022

Mental Health, Lin Marshall Brummels

Oakwood

No abstract provided.


One-Act Plays, Nick Bertelson Sep 2022

One-Act Plays, Nick Bertelson

Oakwood

No abstract provided.


Son Can You Play Me A Memory?, Jim Reese Sep 2022

Son Can You Play Me A Memory?, Jim Reese

Oakwood

No abstract provided.


Homecoming Parade, Todd Williams Sep 2022

Homecoming Parade, Todd Williams

Oakwood

No abstract provided.


Last Night In Rapid City, Todd Williams Sep 2022

Last Night In Rapid City, Todd Williams

Oakwood

No abstract provided.


Love In The Time Of Caldera, Todd Williams Sep 2022

Love In The Time Of Caldera, Todd Williams

Oakwood

No abstract provided.


Evening On The Causeway, Joseph Eisenhart Sep 2022

Evening On The Causeway, Joseph Eisenhart

Oakwood

No abstract provided.


Butchering Day, Jeffrey Wald Sep 2022

Butchering Day, Jeffrey Wald

Oakwood

No abstract provided.


Butcherbird, Courtney Huse Wika Sep 2022

Butcherbird, Courtney Huse Wika

Oakwood

No abstract provided.


The Museum Of Roadside Trash, Courtney Huse Wika Sep 2022

The Museum Of Roadside Trash, Courtney Huse Wika

Oakwood

No abstract provided.


Homecoming, Courtney Huse Wika Sep 2022

Homecoming, Courtney Huse Wika

Oakwood

No abstract provided.


Watercolors, Jeanne Emmons Sep 2022

Watercolors, Jeanne Emmons

Oakwood

Five Paintings:
Resurrection
Bison Grazing
Overhang
Gridmelt
Nightguard


Deus Ex Machina, Erika Saunders Sep 2022

Deus Ex Machina, Erika Saunders

Oakwood

No abstract provided.


Cloud Shadow, Brandon Krieg Sep 2022

Cloud Shadow, Brandon Krieg

Oakwood

No abstract provided.


Prairie Flamingoes, Linda Hallstrom Sep 2022

Prairie Flamingoes, Linda Hallstrom

Oakwood

No abstract provided.


Midsummer's Morn, Norma Najacht Sep 2022

Midsummer's Morn, Norma Najacht

Oakwood

No abstract provided.