Digital Commons Network^™

Assessing Predictive Discrimination Performance Of Biomarkers In The Presence Of Treatment-Induced Dependent Censoring, Cuihong Zhang, Jing Ning, Steven H Belle, Robert H Squires, Jianwen Cai, Ruosha Li

Faculty, Staff and Student Publications

In medical studies, some therapeutic decisions could lead to dependent censoring for the survival outcome of interest. This is exemplified by a study of paediatric acute liver failure, where death was subject to dependent censoring due to liver transplantation. Existing methods for assessing the predictive performance of biomarkers often pose the independent censoring assumption and are thus not applicable. In this work, we propose to tackle the dependence between the failure event and dependent censoring event using auxiliary information in multiple longitudinal risk factors. We propose estimators of sensitivity, specificity and area under curve, to discern the predictive power of …

Assessing Urinary Phenol And Paraben Mixtures In Pregnant Women With And Without Gestational Diabetes Mellitus: A Case-Control Study, Wei-Jen Chen, Candace Robledo, Erin M Davis, Jean R Goodman, Chao Xu, Jooyeon Hwang, Amanda E Janitz, Tabitha Garwe, Antonia M Calafat, Jennifer D Peck

Faculty, Staff and Student Publications

Prior studies have identified the associations between environmental phenol and paraben exposures and increased risk of gestational diabetes mellitus (GDM), but no study addressed these exposures as mixtures. As methods have emerged to better assess exposures to multiple chemicals, our study aimed to apply Bayesian kernel machine regression (BKMR) to evaluate the association between phenol and paraben mixtures and GDM. This study included 64 GDM cases and 237 obstetric patient controls from the University of Oklahoma Medical Center. Mid-pregnancy spot urine samples were collected to quantify concentrations of bisphenol A (BPA), benzophenone-3, triclosan, 2,4-dichlorophenol, 2,5-dichlorophenol, butylparaben, methylparaben, and propylparaben. Multivariable …

Does Hospital Location Matter? Association Of Neighborhood Socioeconomic Disadvantage With Hospital Quality In Us Metropolitan Settings, Nwabunie Nwana, Wenyaw Chan, James Langabeer, Bita Kash, Trudy Millard Krause

Faculty, Staff and Student Publications

An aspect of a hospital's location, such as its degree of socioeconomic disadvantage, could potentially affect quality ratings of the hospital; yet, few studies have granularly explored this relationship in United States (US) metropolitan areas characterized by a wide breadth of socioeconomic disparities across neighborhoods. An understanding of the effect of neighborhood socioeconomic disadvantage on hospital quality of care is informative for targeting resources in poor neighborhoods. We assessed the association of neighborhood socioeconomic disadvantage with hospital quality of care across several areas of quality (including mortality, readmission, safety, patient experience, effectiveness of care, summary and overall star rating) in …

Clinical Significance And Potential Role Of Trimethylamine N-Oxide In Neurological And Neuropsychiatric Disorders, Sowjanya Mudimela, Narahari Koppa Vishwanath, Anilkumar Pillai, Rodrigo Morales, Sean P Marrelli, Tatiana Barichello, Vijayasree V Giridharan

Faculty, Staff and Student Publications

Research in the last three decades has attracted the attention of many scientists and industrialists on the gut microbiome and its metabolites. Among many of these metabolites, trimethylamine oxide. Dietary choline, phosphatidylcholine, carnitine, and betaine produces TMAO that with other gut metabolites such as TMA (trimethylamine), and short-chain fatty acids (SCFA) enter the circulation. Finally they reach the brain through the blood-brain barrier (BBB) where they are involved in several physiological functions such as brain development, neurogenesis, and behavior. Gut-microbiota composition is influenced by diet, lifestyle, antibiotics, and age resulting in dysbiosis. Several studies have confirmed that altered TMAO levels …

Evalution Of Peripheral Neuropathy Among Childhood Cancer Patients, Deborah R. Lee

Dissertations

The principal toxicity for children who receive vincristine for the treatment of acute lymphocytic leukemia (ALL) is peripheral neuropathy, with symptoms that negatively affect physical function and may require the reduction or withdrawal of chemotherapy; even though cumulative dosing has not been shown to increase peripheral neuropathy. This population not only has to deal with the physical challenges of cancer but also can have psychosocial and cognitive effects from treatment. Utilizing secondary analysis, the purpose of this dissertation is to examine peripheral neuropathy (PN) trajectory during the second year of ALL treatment which has not been investigated in children receiving …

Why Do The Police Reject Counseling? An Examination Of Necessary Changes To Police Subculture. Necessary Changes To Police Subculture., Noel Otu, Ntiense E. Otu

Criminal Justice Faculty Publications

This paper reviews the concept of police subculture and examines its role in the management and acceptance of treatment for stress-related injury. In particular, we examine the impact of stigma that attaches to treatment within this subculture. The persistence of the dominant police subculture remains a significant obstacle to officers seeking treatment for stress-related illnesses. The subculture has historically resisted acknowledging the need for treatment in response to the occupational and/or organizational stress-related injury that results from frequent exposure to work-related trauma. Many police administrators are still embedded within and resist changes to the subculture, which results in an atmosphere …

November 2022 Human Resources Connection, Georgia Southern University

Human Resources (2010-2023)

• Make a Difference in Georgia

• NOVEMBER Fire Safety Tips!

• R E C R U I T I N G S E L F S E R V I C E T R A I N I N G

• St. Joseph’s/Candler Mobile Mammography Unit is Coming to YOU!

• Upcoming USG Well-Being Events

• Class C Operator/ WEX Card Training Update

• Tap Deadline!

How To Tame A Jaguar, Ashley Castañeda, Special Collections, Fleet Library

9th Baker & Whitehill Student Artists' Book Contest 2023

GRAND PURCHASE PRIZE | $500 Purchase prize winners receive a cash reward and the books are added to the Fleet Library at RISD Special Collections' Artists' Book collection. Entry for the 9th Annual Baker & Whitehill Student Artists' Book Contest. Opening Reception Thursday, March 02, 2023, Fleet Library, Main Reading Room. Juror: Andre Lee Bassuet.

Recorded In Fabric, Zoe Maxwell, Special Collections, Fleet Library

9th Baker & Whitehill Student Artists' Book Contest 2023

HONORABLE MENTION | $100 Entry for the 9th Annual Baker & Whitehill Student Artists' Book Contest. Opening Reception Thursday, March 02, 2023, Fleet Library, Main Reading Room. Juror: Andre Lee Bassuet.

ריקודים (Dances), Hili Slav, Special Collections, Fleet Library

9th Baker & Whitehill Student Artists' Book Contest 2023

Entry for the 9th Annual Baker & Whitehill Student Artists' Book Contest. Opening Reception Thursday, March 02, 2023, Fleet Library, Main Reading Room. Juror: Andre Lee Bassuet.

|=[[[]]]=|, Linlin Yu, Special Collections, Fleet Library

9th Baker & Whitehill Student Artists' Book Contest 2023

Entry for the 9th Annual Baker & Whitehill Student Artists' Book Contest. Opening Reception Thursday, March 02, 2023, Fleet Library, Main Reading Room. Juror: Andre Lee Bassuet.

An Ode To My Aunties: Melted Into The Pot, Ava Buccino, Special Collections, Fleet Library

9th Baker & Whitehill Student Artists' Book Contest 2023

Entry for the 9th Annual Baker & Whitehill Student Artists' Book Contest. Opening Reception Thursday, March 02, 2023, Fleet Library, Main Reading Room. Juror: Andre Lee Bassuet.

Confession, Sihan Zhu, Special Collections, Fleet Library

9th Baker & Whitehill Student Artists' Book Contest 2023

AMERICAN PRINTING HISTORY ASSOCIATION - New England Chapter Purchase Prize | $375 Purchase prize winners receive a cash reward and the books are added to the Fleet Library at RISD Special Collections' Artists' Book collection. Entry for the 9th Annual Baker & Whitehill Student Artists' Book Contest. Opening Reception Thursday, March 02, 2023, Fleet Library, Main Reading Room. Juror: Andre Lee Bassuet.

Emerging Best Practices In International Atmospheric Trust Case Law, Rachel M. Pemberton, Michael Blumm

Utah Law Review

With climate change litigation proliferating throughout the world, a substantial body of case law is emerging. As part of a project of the IUCN World Commission on Environmental Law's Climate Change Specialist Group, this Article, a version of which will be included in a “Judicial Handbook on Climate Litigation,” explains the public trust doctrine’s influence on climate change litigation internationally. We select what we view as judicial “best practices” as a kind of restatement of international atmospheric trust law in 2022. International atmospheric trust law is at the forefront of many best practices, as state and federal courts in the …

Interpreting State Statutes In Federal Court, Aaron-Andrew P. Bruhl

Faculty Publications

This Article addresses a problem that potentially arises whenever a federal court encounters a state statute. When interpreting the state statute, should the federal court use the state’s methods of statutory interpretation—the state’s canons of construction, its rules about the use of legislative history, and the like—or should the court instead use federal methods of statutory interpretation? The question is interesting as a matter of theory, and it is practically significant because different jurisdictions have somewhat different interpretive approaches. In addressing itself to this problem, the Article makes two contributions. First, it shows, as a normative matter, that federal courts …

Asking The Right Questions To Solve Algebraic Word Problems, Ege Yi̇ği̇t Çeli̇k, Zeynel Orulluoğlu, Ridvan Mertoğlu, Selma Teki̇r

Turkish Journal of Electrical Engineering and Computer Sciences

Word algebra problems are among challenging AI tasks as they combine natural language understanding with a formal equation system. Traditional approaches to the problem work with equation templates and frame the task as a template selection and number assignment to the selected template. The recent deep learning-based solutions exploit contextual language models like BERT and encode the natural language text to decode the corresponding equation system. The proposed approach is similar to the template-based methods as it works with a template and fills in the number slots. Nevertheless, it has contextual understanding because it adopts a question generation and answering …

The Quarterly Interview: Alexandria Chisholm, Alexandria Chisholm

LOEX Quarterly

No abstract provided.

Cancer Research Across Africa: A Comparative Bibliometric Analysis, Miriam Mutebi, Grant Lewison, Ajay Aggarwal, Olusegun Isaac Alatise, Christopher Booth, Miska Cira, Surbhi Grover, Ophira Ginsburg, Julie Gralow, Serine Gueye

General Surgery, East Africa

Introduction Research is a critical pillar in national cancer control planning. However, there is a dearth of evidence for countries to implement affordable strategies. The WHO and various Commissions have recommended developing stakeholder-based needs assessments based on objective data to generate evidence to inform national and regional prioritisation of cancer research needs and goals.

Methodology Bibliometric algorithms (macros) were developed and validated to assess cancer research outputs of all 54 African countries over a 12-year period (2009–2020). Subanalysis included collaboration patterns, site and domain-specific focus of research and understanding authorship dynamics by both position and sex. Detailed subanalysis was performed …

Improving (And Avoiding) Interstate Interpretive Encounters, Aaron-Andrew P. Bruhl

Faculty Publications

State courts often encounter the statutes of other states. Any encounter with another state’s statutes raises an interesting but inconspicuous question about choice of law. In particular, the interstate encounter presents a choice of interpretive law. Despite some universal practices in statutory interpretation, there are methodological differences across jurisdictions—both at the level of overall approach and in the details of particular interpretive canons. When a state court encounters the statute of a sister state, may the forum state use its own interpretive methods or must it instead use the methods of the enacting state?

The existing doctrine on this choice-of-law …

Nomos, Narrative, And Nephi: Legal Interpretation In The Book Of Mormon, Nathan B. Oman

Faculty Publications

The Book of Mormon helped launch one of America’s most successful religions, and millions around the world accept it as scripture. It is thus one of the more influential books to have been published in the United States. Ironically, precisely because of its role in the founding of Mormonism, the text of the Book of Mormon has often been ignored. Recently, however, the Book of Mormon has begun to attract the attention of scholars whose interest in the text goes beyond either religious devotion or the academic study of Mormonism. Rather, they look to the text as a literary creation …

The Future Of College Sports After Alston: Reforming The Ncaa Via Conditional Antitrust Immunity, Nathaniel Grow

William & Mary Law Review

In June 2021, a unanimous U.S. Supreme Court issued its eagerly anticipated decision in National Collegiate Athletic Association v. Alston, ruling for the first time that NCAA rules governing student-athlete eligibility are subject to full scrutiny under federal antitrust law. Although the immediate impact of the Alston decision was rather modest—merely requiring the NCAA to allow its schools to compete by offering prospective players education-related benefits such as laptop computers and stipends for future graduate-level study—the Court hinted that it was prepared to extend the logic of this ruling much further, calling into question the legality of the NCAA’s …

A World Without Roe: The Constitutional Future Of Unwanted Pregnancy, Julie C. Suk

William & Mary Law Review

With the demise of Roe v. Wade, the survival of abortion access in America will depend on new legal paths. In the same moment that Dobbs v. Jackson Women’s Health Organization has constrained access to abortion in the United States, other constitutional democracies have moved in the opposite direction, expanding access to safe, legal, and free abortions. They have done so without reasoning from Roe’s vision of the private zone of unwanted pregnancy. The development of abortion law outside the United States provides critical insights that can inform future efforts to vindicate the constitutional rights of women facing …

A Case Report Of Concurrent Cryptococcal And Tuberculous Meningitis In An Immunosuppressed Renal Transplant Patient, Linda Barasa, Ahmed Sokwala, Felix Riunga, Dilraj Sokhi

Internal Medicine, East Africa

Infections after renal transplant are a common cause of morbidity and are commonly due to Cytomegalovirus (CMV), Cryptococcus, Mycobacterium tuberculosis, and Aspergillus. Concurrent infections with both cryptococcal and tuberculous aetiologies are rare within the central nervous system (CNS). We present a case of a 67-year-old male patient who presented with three weeks of headaches, confusion, unsteady gait, and seizures. He had type 2 diabetes mellitus and hypertension. He had a kidney transplant three years prior and was on three immunosuppressive agents. He was HIV-negative. He was evaluated and found to have cryptococcal meningitis and received appropriate treatment with liposomal amphotericin …

Misinformation And Elections, Wolf Law Library, William & Mary Law School

Library Book Displays

Selections from the collection on elections and misinformation.

On display in the Wolf Law Library November 2022.

Curated by Michael Umberger and Devan Orr.

Vaginal Microbiota In Women With Spontaneous Preterm Labor Versus Those With Term Labor In Kenya: A Case Control Study, Edgar Gulavi, Fridah Mwendwa, David Atandi, Patricia Okiro, Michael Hall, Robert G. Beiko, Rodney Adam

Obstetrics and Gynaecology, East Africa

Background: Preterm birth is a global problem with about 12% of births in sub-Saharan Africa occurring before 37 weeks of gestation. Several studies have explored a potential association between vaginal microbiota and preterm birth, and some have found an association while others have not. We performed a study designed to determine whether there is an association with vaginal microbiota and/or placental microbiota and preterm birth in an African setting.

Methods: Women presenting to the study hospital in labor with a gestational age of 26 to 36 weeks plus six days were prospectively enrolled in a study of the …

Labor Augmentation With Oxytocin In Low- And Lower-Middle-Income Countries: A Systematic Review And Meta-Analysis, Monica Lauridsen Kujabi

Obstetrics and Gynaecology, East Africa

Objective: Despite its worldwide use, reviews of oxytocin for labor augmentation include mainly studies from high-income countries. Meanwhile, oxytocin is a potentially harmful medication and risks may be higher in low-resource settings. We conducted a systematic review and meta-analysis of practices, benefits, and risks of oxytocin for labor augmentation in low- and lower-middle-income countries.

Data sources:  PubMed, Embase, PsycINFO, Index Medicus, Cochrane, and Google Scholar were searched for publications until January 1, 2022.

Study eligibility criteria: All studies evaluating oxytocin augmentation rates were included. To investigate benefits and risks, randomized and quasi-randomized trials comparing oxytocin augmentation with placebo or …

Carbon Dots: An Updated Overview On Their Synthesis, Properties, And Applications In Pharmaceutical And Biomedical Sciences, Earle Radha Rani, Majji Usharani, A. Lakshmi Usha

The Thai Journal of Pharmaceutical Sciences

Nowadays, carbon-based materials have acquired more attention in numerous fields including engineering, medicine, and pharmaceutics. As a new class of small carbon nanomaterials, carbon dots are developed due to their excellent physicochemical properties such as spherical shape, non-toxicity, cost effectiveness, facile, biocompatibility, and discrete particles <10 nm in diameter. In 2004, these carbon dots were first discovered accidentally during processing of single walled carbon nanotubes. Carbon dots have created huge excitement due to their advantages such as high water solubility, excellent biocompatibility, and resistance to photo bleaching. Carbon dots show unique properties such as photo stability, low toxicity, fluorescence, photo chemiluminescence, and electrochemiluminescence. Due to these properties, they have a wide range of applications in the field of bioimaging and drug delivery. Carbon dots are classified into two groups: Amorphous based carbon dots and graphene-based quantum dots with sp2 hybridization. The synthesis methods of carbon dots were reviewed along with their advantages and disadvantages. The applications of carbon dots in drug delivery, gene delivery, targeted drug delivery, crossing blood–brain barrier, and bio imaging were discussed.

Understanding Deviance And Victimization In Cyber Space Among Diverse Populations, Insun Park

International Journal of Cybersecurity Intelligence & Cybercrime

Recent years have witnessed a growing academic interest in deviance and victimization in the cyber space. The current issue of the International Journal of Cybersecurity Intelligence and Cybercrime features three empirical research articles on online behavior of traditionally under-researched populations and a review of much waited book on digital forensics and investigation. This paper was prepared to introduce these important scholarly works in the context of newly emerging scholarship that focuses on the experiences of diverse subgroups in cyberspace.

Aggressive Reality Docuseries And Cyberbullying: A Partial Test Of Glaser’S Differential Identification Theory, J. Ra’Chel Fowler, Darren R. Beneby, Kenethia L. Fuller

International Journal of Cybersecurity Intelligence & Cybercrime

Reality docuseries have dominated primetime airwaves for the greater part of three decades. However, little is known about how viewers who are enamored with the genre’s most aggressive characters are influenced. Using Glaser’s (1956) theory of differential identification, this study employs survey data from 210 college students at a historically Black college and university to explore whether identification with characters from aggressive reality docuseries (ARDs) and the frequency of viewing ARD are positively associated with cyberbullying. Results of multivariate analyses revealed that men were more likely than women to publicly shame others and air other’s dirty laundry online. Additionally, the …

“Elder Scam” Risk Profiles: Individual And Situational Factors Of Younger And Older Age Groups’ Fraud Victimization, Katalin Parti

International Journal of Cybersecurity Intelligence & Cybercrime

In an attempt to understand how differently fraud works depending on a victim’s age, we have examined the effects of situational (lifestyle-routine activities), self-control, and sociodemographic variables on scam victimization across age groups. The analysis was carried out on a national sample of 2,558 Americans, representative by age, sex, and race, and includes additional factors such as their education, living arrangement, employment, and propensity for reporting a crime or asking for help. The results substantiate research findings of the contribution of self-control and LRAT in predicting victimization in general but could not identify major situational and individual differences between older …