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Articles 647011 - 647040 of 5171865
Full-Text Articles in Entire DC Network
Using Audience Segmentation Approaches To Inform Integrated Family Planning And Maternal Health Programs In Niger, Breakthrough Research
Using Audience Segmentation Approaches To Inform Integrated Family Planning And Maternal Health Programs In Niger, Breakthrough Research
Sexual and Reproductive Health, Rights, and Choices
Understanding the specific behavioral determinants and barriers to health-seeking for reproductive and maternal health services is critical to developing social and behavior change (SBC) programs that can best address the needs of the community. Effective SBC interventions can incorporate audience segmentation, the practice of dividing an audience into subgroups based on demographic, psychographic, and/or behavioral factors to develop tailored SBC approaches that are most likely to resonate with each audience subgroup. This brief presents study results of audience profiles for women of reproductive age in Niger with a focus on three reproductive and maternal health behaviors. It is intended to …
November 2022, Swosu Bulldog Wellness Committee
November 2022, Swosu Bulldog Wellness Committee
SWOSU BULLDOG WELLNESS
Fruits aren't just for Summertime!
Some fruits aren't as plentiful during the winter months as the summertime, but here are some delicious citrus and other fruits that are very much in season and packed with vital nutrients we need to stay healthy and strong during the colder times of the year.
Here's a rundown of some of the best ones and how they can help keep you healthy.
Rare Genetic Variants Explain Missing Heritability In Smoking, Seon-Kyeong Jang, Luke Evans, Allison Fialkowski, Donna K Arnett, Allison E Ashley-Koch, Kathleen C Barnes, Diane M Becker, Joshua C Bis, John Blangero, Eugene R Bleecker, Meher Preethi Boorgula, Donald W Bowden, Jennifer A Brody, Brian E Cade, Brenda W Campbell Jenkins, April P Carson, Sameer Chavan, L Adrienne Cupples, Brian Custer, Scott M Damrauer, Sean P David, Mariza De Andrade, Carla L Dinardo, Tasha E Fingerlin, Myriam Fornage, Barry I Freedman, Melanie E Garrett, Sina A Gharib, David C Glahn, Jeffrey Haessler, Susan R Heckbert, John E Hokanson, Lifang Hou, Shih-Jen Hwang, Matthew C Hyman, Renae Judy, Anne E Justice, Robert C Kaplan, Sharon L R Kardia, Shannon Kelly, Wonji Kim, Charles Kooperberg, Daniel Levy, Donald M Lloyd-Jones, Ruth J F Loos, Ani W Manichaikul, Mark T Gladwin, Lisa Warsinger Martin, Mehdi Nouraie, Olle Melander, Deborah A Meyers, Courtney G Montgomery, Kari E North, Elizabeth C Oelsner, Nicholette D Palmer, Marinelle Payton, Anna L Peljto, Patricia A Peyser, Michael Preuss, Bruce M Psaty, Dandi Qiao, Daniel J Rader, Nicholas Rafaels, Susan Redline, Robert M Reed, Alexander P Reiner, Stephen S Rich, Jerome I Rotter, David A Schwartz, Aladdin H Shadyab, Edwin K Silverman, Nicholas L Smith, J Gustav Smith, Albert V Smith, Jennifer A Smith, Weihong Tang, Kent D Taylor, Marilyn J Telen, Ramachandran S Vasan, Victor R Gordeuk, Zhe Wang, Kerri L Wiggins, Lisa R Yanek, Ivana V Yang, Kendra A Young, Kristin L Young, Yingze Zhang, Dajiang J Liu, Matthew C Keller, Scott Vrieze
Rare Genetic Variants Explain Missing Heritability In Smoking, Seon-Kyeong Jang, Luke Evans, Allison Fialkowski, Donna K Arnett, Allison E Ashley-Koch, Kathleen C Barnes, Diane M Becker, Joshua C Bis, John Blangero, Eugene R Bleecker, Meher Preethi Boorgula, Donald W Bowden, Jennifer A Brody, Brian E Cade, Brenda W Campbell Jenkins, April P Carson, Sameer Chavan, L Adrienne Cupples, Brian Custer, Scott M Damrauer, Sean P David, Mariza De Andrade, Carla L Dinardo, Tasha E Fingerlin, Myriam Fornage, Barry I Freedman, Melanie E Garrett, Sina A Gharib, David C Glahn, Jeffrey Haessler, Susan R Heckbert, John E Hokanson, Lifang Hou, Shih-Jen Hwang, Matthew C Hyman, Renae Judy, Anne E Justice, Robert C Kaplan, Sharon L R Kardia, Shannon Kelly, Wonji Kim, Charles Kooperberg, Daniel Levy, Donald M Lloyd-Jones, Ruth J F Loos, Ani W Manichaikul, Mark T Gladwin, Lisa Warsinger Martin, Mehdi Nouraie, Olle Melander, Deborah A Meyers, Courtney G Montgomery, Kari E North, Elizabeth C Oelsner, Nicholette D Palmer, Marinelle Payton, Anna L Peljto, Patricia A Peyser, Michael Preuss, Bruce M Psaty, Dandi Qiao, Daniel J Rader, Nicholas Rafaels, Susan Redline, Robert M Reed, Alexander P Reiner, Stephen S Rich, Jerome I Rotter, David A Schwartz, Aladdin H Shadyab, Edwin K Silverman, Nicholas L Smith, J Gustav Smith, Albert V Smith, Jennifer A Smith, Weihong Tang, Kent D Taylor, Marilyn J Telen, Ramachandran S Vasan, Victor R Gordeuk, Zhe Wang, Kerri L Wiggins, Lisa R Yanek, Ivana V Yang, Kendra A Young, Kristin L Young, Yingze Zhang, Dajiang J Liu, Matthew C Keller, Scott Vrieze
Faculty, Staff and Student Publications
Common genetic variants explain less variation in complex phenotypes than inferred from family-based studies, and there is a debate on the source of this 'missing heritability'. We investigated the contribution of rare genetic variants to tobacco use with whole-genome sequences from up to 26,257 unrelated individuals of European ancestries and 11,743 individuals of African ancestries. Across four smoking traits, single-nucleotide-polymorphism-based heritability ([Formula: see text]) was estimated from 0.13 to 0.28 (s.e., 0.10-0.13) in European ancestries, with 35-74% of it attributable to rare variants with minor allele frequencies between 0.01% and 1%. These heritability estimates are 1.5-4 times higher than past …
The Association Between Egocentric Sexual Networks And Sexual Meeting Venues With Prep Conversation And Encouragement For Use Among Latinx Men Who Have Sex With Men, Mariano Kanamori, Cho-Hee Shrader, Juan Flores-Arroyo, Ariana Johnson, Edda Rodriguez, Stephen Fallon, John Skvoretz, Victor Gonzalez, Susanne Doblecki-Lewis, Adam Carrico, Kayo Fujimoto, Mark Williams, Steven Safren
The Association Between Egocentric Sexual Networks And Sexual Meeting Venues With Prep Conversation And Encouragement For Use Among Latinx Men Who Have Sex With Men, Mariano Kanamori, Cho-Hee Shrader, Juan Flores-Arroyo, Ariana Johnson, Edda Rodriguez, Stephen Fallon, John Skvoretz, Victor Gonzalez, Susanne Doblecki-Lewis, Adam Carrico, Kayo Fujimoto, Mark Williams, Steven Safren
Faculty, Staff and Student Publications
Despite the increasing availability of pre-exposure prophylaxis (PrEP), Latinx men who have sex with men (LMSM) are not receiving PrEP-related information. To understand the influence of LMSM sexual networks on PrEP-related conversations and encouragement to use PrEP, this cross-sectional egocentric network study characterized the PrEP-related communication of 130 LMSM egos with 507 sexual partners (alters). Participants were recruited using respondent-driven sampling methods from a Miami-Dade County community-health organization. Egocentric-level data were collected from 2018-2019 and analyzed using multilevel modeling. Of egos, 30% reported using PrEP. Closeness between participants and sexual partners played a role in PrEP conversation and encouragement. Participants …
8605 Gynecologic Laparoscopy In The Bariatric Patient: A Retrospective Review Of Abdominal Access And Associated Complications, G. H. Shukr, M. Shukr, D. I. Eisenstein, Arthur M. Carlin, Joelle Abood
8605 Gynecologic Laparoscopy In The Bariatric Patient: A Retrospective Review Of Abdominal Access And Associated Complications, G. H. Shukr, M. Shukr, D. I. Eisenstein, Arthur M. Carlin, Joelle Abood
Obstetrics, Gynecology and Women's Health Services Meeting Abstracts
Study Objective: To provide clinical direction on laparoscopic abdominal entry techniques in women with known history of laparoscopic Roux-en-Y Gastric Bypass (RYGB) undergoing gynecologic surgery and to identify any associated complications.
Design: Retrospective Chart Review and Case Series.
Setting: Community-based tertiary care medical center.
Patients or Participants: All patients who underwent RYGB between 2013 and 2020 and had a subsequent gynecologic procedure.
Interventions: Abdominal access.
Measurements and Main Results: Thirty-one patients were identified, of which 18 had an adnexal surgery and 13 a hysterectomy. At time of surgery, the mean age was 44 years and body mass index was 32 …
Real-Time Joint Ocean Acoustics And Circulation Modeling In The 2021 New England Shelf Break Acoustics Experiment (L), Brendan J. Decourcy, Ying-Tsong Lin, Weifeng Gordon Zhang, Emma Reeves Ozanich, Natalie Kukshtel, Martin Siderius, Glen Gawarkiewicz, Jacob Forsyth
Real-Time Joint Ocean Acoustics And Circulation Modeling In The 2021 New England Shelf Break Acoustics Experiment (L), Brendan J. Decourcy, Ying-Tsong Lin, Weifeng Gordon Zhang, Emma Reeves Ozanich, Natalie Kukshtel, Martin Siderius, Glen Gawarkiewicz, Jacob Forsyth
Electrical and Computer Engineering Faculty Publications and Presentations
During the spring of 2021, a coordinated multi-vessel effort was organized to study physical oceanography, marine geology and biology, and acoustics on the northeast United States continental shelf, as part of the New England Shelf Break Acoustics (NESBA) experiment. One scientific goal was to establish a real-time numerical model aboard the research vessel with high spatial and temporal resolution to predict the oceanography and sound propagation within the NESBA study area. The real-time forecast model performance and challenges are reported in this letter without adjustment or re-simulation after the cruise. Future research directions for post-experiment studies are also suggested.
Contemporary Primary Treatment Of Women With Stage Ii-Iv Low-Grade Serous Ovarian/Peritoneal Cancer (Lgsoc): Determinants Of Relapse And Disease-Free Survival, David M Gershenson, Lauren P Cobb, Shannon N Westin, Yingao Zhang, Amir Jazaeri, Anais Malpica, Charlotte C Sun
Contemporary Primary Treatment Of Women With Stage Ii-Iv Low-Grade Serous Ovarian/Peritoneal Cancer (Lgsoc): Determinants Of Relapse And Disease-Free Survival, David M Gershenson, Lauren P Cobb, Shannon N Westin, Yingao Zhang, Amir Jazaeri, Anais Malpica, Charlotte C Sun
Faculty, Staff and Student Publications
Objective: The purpose of the present study is to describe a cohort who received contemporary primary treatment for stage II-IV low-grade serous ovarian/peritoneal cancer (LGSOC), including patient characteristics and determinants of relapse and disease-free survival.
Methods: The study included 99 patients: 1) with pathologically confirmed stage II-IV LGSOC of the ovary or peritoneum, 2) who underwent primary treatment consisting of cytoreductive surgery and either a) platinum/taxane chemotherapy followed by aromatase inhibitor maintenance therapy or b) aromatase inhibitor monotherapy, and 3) for whom there was availability of clinical data. Descriptive statistics were used to characterize clinicodemographic features. Subgroups were compared for …
Impact Of Conditioning Chemotherapy On Lymphocyte Kinetics And Outcomes In Lbcl Patients Treated With Car T-Cell Therapy, Paolo Strati, Andrew P Jallouk, Ryan Sun, Jaihee Choi, Kaberi Das, Hua-Jay Cherng, Sairah Ahmed, Hun J Lee, Swaminathan P Iyer, Ranjit Nair, Loretta J Nastoupil, Raphael E Steiner, Chad D Huff, Yao Yu, Haleigh Mistry, Brittany Pulsifer, Mansoor Noorani, Neeraj Saini, Elizabeth J Shpall, Partow Kebriaei, Christopher R Flowers, Jason R Westin, Michelle A T Hildebrandt, Sattva S Neelapu
Impact Of Conditioning Chemotherapy On Lymphocyte Kinetics And Outcomes In Lbcl Patients Treated With Car T-Cell Therapy, Paolo Strati, Andrew P Jallouk, Ryan Sun, Jaihee Choi, Kaberi Das, Hua-Jay Cherng, Sairah Ahmed, Hun J Lee, Swaminathan P Iyer, Ranjit Nair, Loretta J Nastoupil, Raphael E Steiner, Chad D Huff, Yao Yu, Haleigh Mistry, Brittany Pulsifer, Mansoor Noorani, Neeraj Saini, Elizabeth J Shpall, Partow Kebriaei, Christopher R Flowers, Jason R Westin, Michelle A T Hildebrandt, Sattva S Neelapu
Faculty, Staff and Student Publications
Conditioning chemotherapy (CCT) has been shown to be essential for optimal efficacy of chimeric antigen receptor (CAR) T-cell therapy. Here, we determined whether the change in absolute lymphocyte count, referred to as delta lymphocyte index (DLIx), may serve as a surrogate marker for pharmacodynamic effects of CCT and whether it associated with germline genetic variants in patients with large B-cell lymphoma (LBCL). One-hundred and seventy-one patients were included, of which 86 (50%) received bridging therapy post-leukapheresis. Median DLIx was 0.5 × 109/L (range, 0.01-2.75 × 109/L) and was significantly higher in patients who achieved complete response (p = 0.04). On …
Ramping Up For Cost And Performance Improvements, Arthur Zucchetti Lechmann, Guilherme Henrique Lima, João Paulo Lucchi, Paulo Henrique Azevedo Santana, Pedro Kamikihara
Ramping Up For Cost And Performance Improvements, Arthur Zucchetti Lechmann, Guilherme Henrique Lima, João Paulo Lucchi, Paulo Henrique Azevedo Santana, Pedro Kamikihara
Student Works
The objective of this Research Project was to study the possible benefits of developing an improved Metering Control System. This study identified potential cost savings and reduced emissions through the greater use of a Metering Control System. The results of this research have indicated an annual cost reduction of $720,000 in fuel burn and a significant delay time reduction caused by accumulated ground traffic. In addition, during peak hours, it was concluded that savings could be potentially higher. Therefore, by optimizing the ground movement, it is also expected a lower level of CO2 emissions, an increased safety level due to …
Testing And Verification For The Open Source Release Of The Horizon Simulation Framewortesting And Verification For The Open Source Release Of The Horizon Simulation Framework, William J. Balfour
Testing And Verification For The Open Source Release Of The Horizon Simulation Framewortesting And Verification For The Open Source Release Of The Horizon Simulation Framework, William J. Balfour
Master's Theses
Modeling and simulation tools are exceptionally useful for designing aerospace systems because they allow engineers to test and iterate designs before committing the massive resources required for system realization. The Horizon Simulation Framework (HSF) is a time-driven modeling and simulation tool which attempts to optimize how a modeled system could perform a mission profile. After 15 years of development, the HSF team aims to achieve a wider user and developer base by releasing the software open source. To ensure a successful release, the software required extensive testing, and the main scheduling algorithm required protections against new code breaking old functionality. …
Fabrication Of Thin-Film Composite, Reverse-Osmosis Membranes With Polyethylenimine Modifications For Enhancing Membrane Fouling Resistance, Stephanie N. Hamilton
Fabrication Of Thin-Film Composite, Reverse-Osmosis Membranes With Polyethylenimine Modifications For Enhancing Membrane Fouling Resistance, Stephanie N. Hamilton
Master's Theses
Increasing water reuse opportunities for communities has become increasingly important as access to clean water is becoming more scarce. Reverse Osmosis (RO) is an advanced treatment technology used in water recycling wastewater for potable reuse applications. RO is a promising technology; however, the membranes have limitations including their high energy demand and their susceptibility to membrane fouling. The main objective of this study was to develop a reproducible method for the fabrication of RO membranes with enhanced flux and reduced susceptibility to fouling. Literature contains numerous publications on fabrication of thin film composite (TFC) RO membranes with high performance. However, …
A Comparison Of The Economic Impact Of Horse Racing Tracks In Kentucky Versus Neighboring Indiana, Thomas E. Lambert
A Comparison Of The Economic Impact Of Horse Racing Tracks In Kentucky Versus Neighboring Indiana, Thomas E. Lambert
Faculty and Staff Scholarship
The Louisville metro area is one that spans two states—Kentucky and Indiana. Since the University of Louisville has many students and employees who come from the Hoosier State, it would be interesting to see how the two states compare when it comes to what has been labeled a “signature” industry for the Commonwealth of Kentucky—horse racing.
The Economic Impact Of The Red Mile On The Lexington Metro Area, Thomas E. Lambert
The Economic Impact Of The Red Mile On The Lexington Metro Area, Thomas E. Lambert
Faculty and Staff Scholarship
The Red Mile Racetrack and Red Mile Gaming Center in Lexington, Kentucky have a harness racetrack, and the track has had a solid tradition for quality harness racing going back to its start in 1875 (Red Mile 2022). This paper examines what economic impact the racetrack and gaming center have on the Lexington metro area (Bourbon, Clark, Fayette, Jessamine, Scott, and Woodford counties in Kentucky) on a yearly basis.
Wellness Wheel Action Guide, Michele Kroll
Advancing The Use Of Fecal Sludge For Timelier And Better-Quality Epidemiological Data In Low- And Middle-Income Countries For Pandemic Prevention., Petros Chigwechokha, Renée Street, Rochelle H. Holm
Advancing The Use Of Fecal Sludge For Timelier And Better-Quality Epidemiological Data In Low- And Middle-Income Countries For Pandemic Prevention., Petros Chigwechokha, Renée Street, Rochelle H. Holm
Faculty and Staff Scholarship
No abstract provided.
The Employment Situation Of Veterans: October 2022, Institute For Veterans And Military Families At Syracuse University
The Employment Situation Of Veterans: October 2022, Institute For Veterans And Military Families At Syracuse University
Institute for Veterans and Military Families
Veteran employment trends and statistics among various demographics during October 2022
Preparing Students For The Future With Integrative Studies, Singapore Management University
Preparing Students For The Future With Integrative Studies, Singapore Management University
SMU Press Releases and News
Singapore Management University (SMU) today hosted the Education Leaders’ Symposium with a theme of “Integrative Studies and the Future of Learning”. The one-day event focused on equipping educators with a knowhow of adopting integrative methodology in their classrooms, to steer students towards integrative learning, a programme offered by SMU College of Integrative Studies (CIS). The Symposium was graced by Guest-of-Honour Mr Chan Chun Sing, Minister for Education, who addressed the audience via a pre-recorded message. In his speech, Mr Chan congratulated SMU on the official launch of its CIS, an incubator of interdisciplinary learning. The CIS is an integral element …
Insights Into Novel Therapeutic Targets And Molecular Aspects In Polycystic Ovarian Syndrome: A Review, Rukaiah Fatma Begum, M. Sumithra, V. Chitra, Sharmila Devi
Insights Into Novel Therapeutic Targets And Molecular Aspects In Polycystic Ovarian Syndrome: A Review, Rukaiah Fatma Begum, M. Sumithra, V. Chitra, Sharmila Devi
The Thai Journal of Pharmaceutical Sciences
Polycystic ovarian syndrome (PCOS) is a common endocrine syndrome in women associated with many other complications such as insulin resistance, obesity, hirsutism, increased risk of cardiovascular diseases, and infertility. As the pathophysiology of the syndrome still is not clear, it is difficult for the health-care professionals to precisely treat the syndrome. The cause of this syndrome is also unknown, but the evidences suggest that the factors such as environment, diet, and lifestyle are also a very common cause now a day for the syndrome. Recent pathophysiology of PCOS based on the Anti-Mullerian Hormone (AMH) and melatonin levels has been seen …
Efficacy Of Investigative Candidate Drugs Against Sars Cov-2: An Update On Pre-Clinical And Clinical Trials, Maryam Bibi, Aatika Sadia, Muhammad Shahzad, Ahmad Irfan, Muhammad Asim Raza Basra
Efficacy Of Investigative Candidate Drugs Against Sars Cov-2: An Update On Pre-Clinical And Clinical Trials, Maryam Bibi, Aatika Sadia, Muhammad Shahzad, Ahmad Irfan, Muhammad Asim Raza Basra
The Thai Journal of Pharmaceutical Sciences
The unprecedented challenges presented by COVID-19 pandemic demands for an urgent development of effective therapeutic strategies against the deadly virus. Researchers thus far have revealed outcomes of pre-clinical and clinical studies of different interventions. This study aims to present overall summary of therapeutics that until this date are reported for their efficacy against COVID-19 in pre-clinical and clinical trials. A thorough literature search was conducted using databases for identification of studies published on the severe acute respiratory syndrome CoV (SARS COV-2) treatment. According to pre-clinical experiments, Nefamostat mesylate, Remdesivir, Chloroquine (CQ), Hydroxychloroquine (HCQ), β-D-N4-hydroxycytidine (NHC EIDD-1931), Ivermectin, Boceprevir, Calpain inhibitors, …
Assessment Of Risk Factors And Prescription Analysis Among Embolic And Atherosclerotic Stroke Patients In A Charitable Hospital-A Retrospective Study, Shanty Mary Jose, Amala Johnson, Akshay Abraham, Uday Venkat Mateti, Adithi Kellarai, Raushan Kumar Chaudhary, Shraddha Shetty
Assessment Of Risk Factors And Prescription Analysis Among Embolic And Atherosclerotic Stroke Patients In A Charitable Hospital-A Retrospective Study, Shanty Mary Jose, Amala Johnson, Akshay Abraham, Uday Venkat Mateti, Adithi Kellarai, Raushan Kumar Chaudhary, Shraddha Shetty
The Thai Journal of Pharmaceutical Sciences
Purpose: Despite the burden of stroke globally, there is a lack of data on the current clinical profile of stroke in middle and low-income countries including, India. Hence, the purpose of this study was to identify risk factors, clinical presentations, and importantly, prescription trends in ischemic stroke patients. Methods: A retrospective study was conducted for six months using data of 350 ischemic stroke patients for the analysis of risk factors and prescription pattern. Results: The incidence of ischemic stroke was higher (66%) in males in compared to (34%) females with mean age of 61.07 ± 11.460. Further the atherosclerotic stroke …
Hepatotoxic And Nephrotoxic Effects Of Chronic Exposure To Vernonia Cinerea Crude Extract On Wistar Rats, Thularath Toommakorn, Sajee Waramit, Patchara Danaisawadi, Kantimanee Pradermwong
Hepatotoxic And Nephrotoxic Effects Of Chronic Exposure To Vernonia Cinerea Crude Extract On Wistar Rats, Thularath Toommakorn, Sajee Waramit, Patchara Danaisawadi, Kantimanee Pradermwong
The Thai Journal of Pharmaceutical Sciences
Vernonia cinerea L. (VC) has been used for smoking cessation and decreased appetite in Thailand. However, the safety of this plant concerning long-term consumption has never been reported. A 6-month toxicity study of VC water crude extract (VCWE) was performed in both genders of Wistar rats at doses of 15, 150, and 1500 mg/kg body weight/day orally. Recovery group received 1500 mg/kg for 6 months and then extended for 14 days without the extract. It was found that the males could not tolerate the highest dose of VCWE. There was no effect on bodyweight, relative organ weight, nor hematological parameters …
Anti-Diabetic Effect Of Interruptins A And B From Cyclosorus Terminans On Mouse Hepatocytes, Sujinda Songtrai, Sireewan Kaewsuwan
Anti-Diabetic Effect Of Interruptins A And B From Cyclosorus Terminans On Mouse Hepatocytes, Sujinda Songtrai, Sireewan Kaewsuwan
The Thai Journal of Pharmaceutical Sciences
Interruptin B from the fern Cyclosorus terminans has been indicated as a ligand of peroxisome proliferator-activated receptor (PPAR)-α and -γ that is known to regulate glucose homeostasis. Interruptin B was previously been implicated to promote glucose consumption into adipocytes. This study aimed to examine the anti-diabetic impact of interruptins A and B on glucose uptake and glycogen synthesis in mouse hepatocytes. Cell viability of FL83B hepatocytes affected by interruptins A and B was determined. The glucose consumption after 12–24 h treatment with compounds was evaluated by glucose oxidase method. The glycogen content was assessed after 24 h incubation using anthrone …
Alcl3 Induced Neuroinflammation And Excitotoxicity In Brain Striatum Mediated Memory And Motor Dysfunction Ameliorated Via Scopoletin Enriched Canscora Decussata Extract, A. Roja, T. Ambiga, Abdul Khayum, Sulaiman Mohammed, Venkatesh Gunasekaran
Alcl3 Induced Neuroinflammation And Excitotoxicity In Brain Striatum Mediated Memory And Motor Dysfunction Ameliorated Via Scopoletin Enriched Canscora Decussata Extract, A. Roja, T. Ambiga, Abdul Khayum, Sulaiman Mohammed, Venkatesh Gunasekaran
The Thai Journal of Pharmaceutical Sciences
Objective: Scopoletin is one of the dynamic and active constituents originate in Canscora decussata (CD) herb from Shankhpushpi family according to Indian system of medicine. This study aimed to characterize and to explore the role of scopoletin enriched CD (SECD) extract on AlCl3-induced neuroinflammation and excitotoxicity in rat model. Methodology & Results: High-performance thin-layer chromatography finger printing of ethanol extract of CD confirmed that enriched scopoletin presence as its main constituent. AlCl3 induced behavioural changes were reversed after SECD (200 and 400 mg/kg, i. p) and Rivastigmine (0.3 mg/kg, i.p) treatment by the way of Y maze, Rota rod, and …
Anti-Inflammatory Activity Of Phenolic-Rich Fraction Of Pandanus Tectorius Fruits Via Reduction Of No Production On Lipopolysaccharide-Stimulated Raw264.7 Cell Lines And Formalin-Induced Paw Oedema, Yosie Andriani, Nadia Madihah Ramli, Noor Suryani Musa, Kanwal Kanwal, Habsah Mohamad, Hermansyah Amir, Murni Nur Islamiah Kassim, Desy Fitrya Syamsumir, Tengku Sifzizul Tengku Muhammad, Suvik Assaw
Anti-Inflammatory Activity Of Phenolic-Rich Fraction Of Pandanus Tectorius Fruits Via Reduction Of No Production On Lipopolysaccharide-Stimulated Raw264.7 Cell Lines And Formalin-Induced Paw Oedema, Yosie Andriani, Nadia Madihah Ramli, Noor Suryani Musa, Kanwal Kanwal, Habsah Mohamad, Hermansyah Amir, Murni Nur Islamiah Kassim, Desy Fitrya Syamsumir, Tengku Sifzizul Tengku Muhammad, Suvik Assaw
The Thai Journal of Pharmaceutical Sciences
Background: The current study is the first study that investigated the potential of phenolic-rich fraction of Pandanus tectorius fruits as an anti-inflammatory agent. The fruit is rich in phenolic compounds, especially from the flavonoids group. Phenolics are known to contribute to an anti-inflammatory activity. Objectives: The first objective of the study was to evaluate the anti-inflammatory potency of phenolic-rich fractions of P. tectorius fruits by in vitro and in vivo studies. The second was to investigate the cytotoxicity against RAW264.7 cell lines, antioxidant, and phenolic contents to support the experiment. Materials and Methods: Sample fractionation was done with hexane, ethyl …
Chitosan Nanogel With Mixed Food Plants And Its Relation To Blood Glucose In Type 2 Diabetes: A Systematic And Meta-Analysis Review Of Observational Studies, Morris Aloysius, Kyriacos N. Felekkis, Christos Petrou, Dimitrios Papandreou, Eleni Andreou
Chitosan Nanogel With Mixed Food Plants And Its Relation To Blood Glucose In Type 2 Diabetes: A Systematic And Meta-Analysis Review Of Observational Studies, Morris Aloysius, Kyriacos N. Felekkis, Christos Petrou, Dimitrios Papandreou, Eleni Andreou
All Works
This systematic review with metanalysis evaluated and analyzed the beneficial effects of certain plants food in type 2 diabetes (T2D) when consumed alone or in combination with chitosan. The main objective of the paper was to examine the relation of chitosan nanogel and mixed food plant (MFP) to control T2D. The databases included Medline, Scopus, PubMed, as well as Cochrane available between the month of January 1990 to January 2021. The eligibility criteria for selecting studies were case-controlled studies that included unripe plantain, bitter yam, okra, and chitosan either used-alone or in combination with non-specified food plants (NSFP). Two-fold autonomous …
Antioxidant And Nephroprotective Effects Of Delphinium Denudatum Root Extract (Medicinal Plant) Against Gentamicin-Induced Nephrotoxicity, Nadeem Ahmad Siddique
Antioxidant And Nephroprotective Effects Of Delphinium Denudatum Root Extract (Medicinal Plant) Against Gentamicin-Induced Nephrotoxicity, Nadeem Ahmad Siddique
The Thai Journal of Pharmaceutical Sciences
Introduction and Objectives: Kidney is a front line organ exposed to the toxicity of gentamicin. The objective of this study was to determine the biopotential of Delphinium denudatum Wall., root a significant medicinal plant, against gentamicin. Materials and Methods: By performing high-performance liquid chromatography, an in vitro antioxidant study was conducted against diphenylpicrylhydrazide (DPPH). In vivo nephroprotective activity was evaluated by administering solo administration of gentamicin (GM; 40 mg/kg b.wt. single dose s.c.) for a period of 1st–13th days followed by hydroalcoholic extract of D. denudatum (HAEDD; 200, 400, and 800 mg/kg b.wt. intragastrically) to the rats for 14th–23rd days. …
Antidiabetic Study And Teratogenicity Evaluation Of Ethanolic Extract Of Chromolaena Odorata Linn., Indah Solihah, Yuni Fitriani, Meutia Reni Noprida, Herlina, Riana Sari Puspita Rasyid, Tri Suciati
Antidiabetic Study And Teratogenicity Evaluation Of Ethanolic Extract Of Chromolaena Odorata Linn., Indah Solihah, Yuni Fitriani, Meutia Reni Noprida, Herlina, Riana Sari Puspita Rasyid, Tri Suciati
The Thai Journal of Pharmaceutical Sciences
There is considerable interest in herbal medicine in developing antidiabetic alternative therapy based on plant-derived compounds that would reduce oral hypoglycemic agent-related adverse effects while staying safe during pregnancy. The purpose of this in vivo study was to evaluate the ethanolic extract of Chromolaena odorata L. leaves (ECOL) in alloxan-induced diabetes and its teratogenic effect. The hypoglycemic impact of ECOL increased when the extract dose was raised. Three doses of ECOL (125, 250, and 500 mg/kg body weight) showed a 27.29%, 34.68%, and 52.24% hypoglycemic effect, respectively. While, the standard insulin (1 IU/kg BW) group shown a 31.38% hypoglycemic effect …
Synthesis And In Silico Study Of New Azetidinones Against Non-Small Cell Lung Cancer By Egfr Inhibition, Jainey P. James, T. C. Aiswarya, Swetha P. Shenoy, Vinod Devaraji
Synthesis And In Silico Study Of New Azetidinones Against Non-Small Cell Lung Cancer By Egfr Inhibition, Jainey P. James, T. C. Aiswarya, Swetha P. Shenoy, Vinod Devaraji
The Thai Journal of Pharmaceutical Sciences
Background: Lung cancer is alarmingly increasing and therapies targeting receptors such as human epidermal growth factor have been found to be emerging in treating lung cancer. Many studies report azetidinone bearing compounds to be cytotoxic. This work aims to prove the anti-lung cancer action of synthesized azetidinones that are through epidermal growth factor receptor (EGFR) inhibition. Materials and Methods: Novel azetidinone derivatives were synthesized from Schiff bases; molecular docking analyzed the interactions with EGFR, and pharmacophore modeling revealed the features responsible for the possible interactions. Moreover, the compounds with good docking scores were selected for anti-lung cancer study by MTT …
Inspire : Vol 5, Issue 11, Department Of Medicine
Inspire : Vol 5, Issue 11, Department Of Medicine
INSPIRE – Department of Medicine Archives
- Message from the Chair
- Medicine at National and International Forums
- Magnificent Launch | Centre for Impact
- Diabetes Technology for Improved Outcomes
- Women in Medicine (WIM) Lunch N Learn
- Team building lunch with Nursing team | a group photo
- In-depth- featuring Prof. Hasnain Ali Shah |Gastroenterology section Featured Faculty | Dr Nida Saddaf Khan | Senior Instructor | Data Science Project “…Your interest and hard work will earn you excellence… and then you don’t need to worry about money as money follows excellence…” What are Academics Around the World Reading This Month?
- Upcoming Events
- What are Academics Around the World Reading …
Smu Appoints Communication And Technology Professor Lim Sun Sun As Inaugural Vice President, Partnerships And Engagement, Singapore Management University
Smu Appoints Communication And Technology Professor Lim Sun Sun As Inaugural Vice President, Partnerships And Engagement, Singapore Management University
SMU Press Releases and News
The Singapore Management University (SMU) is pleased to announce the appointment of Professor Lim Sun Sun (林珊珊 教授) as Vice President, Partnerships and Engagement with effect from 1 December 2022. As Vice President, Partnerships & Engagement (合作与交流总监), Prof Lim will lead teams to deliver SMU’s strategy to be an Engaged City University, primarily in the areas of industry partnership; innovation and entrepreneurship; and international partnerships, within the University’s larger strategic plans. Her team will also support the University’s ambition to distinguish its education and research by enabling strong external partnerships with the private and public sectors, and with academic and …