Digital Commons Network^™

Risk Factors Of Not Reaching Mcid After Elective Lumbar Spine Surgery: A Case Control Study, Travis Hamilton Md, Scott Lim Md, Edwin Telemi Md, Ho Jun Yun Mms, Mohamed Macki Md, Lonni Schultz Phd, Hsueh-Han Yeh Phd, Kylie Springer Ms, Kevin Taliafero Md, Miguelangelo Perez-Cruet Md, Ilyas Aleem Md, Paul Park Md, Richard Easton Md, David Nerenz Phd, Jason Schwalb Md, Muwaffak Abdulhak Md, Victor Chang Md

Medical Student Research Symposium

Background

The therapeutic effect of spine surgery has been traditionally evaluated by physical examination, radiographic findings, and general perception of patient’s health status. However, these assessments are often insufficient to represent surgical outcomes.Patient-reported outcomes (PROs) are tools developed to measures quality outcomes following spinal surgery. Examples include the Patient-Reported Outcomes Measurement Information System Function 4-item Short Form (PROMIS-PF), Visual Analogue Scale (VAS), ODI (Oswestry Disability Index), SF-36 (Short Form Health Survey), and EQ-5D (EuroQuol-5D). The minimum clinically important difference (MCID) is an assessment tool to note the smallest clinical difference in PROs and provides the threshold where patients experience clinical …

The Impact Of Reforming The Medical Student Admissions Training Process On Medical Student Interviewers., Sean Mccarthy, Iyanna Peppers, Kevin Sprague Md, Abhinav Krishnan Phd.

Medical Student Research Symposium

• Title: The Impact of Reforming the Medical Student Admissions’ Training Process on Medical Student Interviewers.

• Authors: Sean McCarthy1, Iyanna Peppers1, Kevin Sprague, M.D.1, Abhinav Krishnan, PhD1

1.Wayne State University School of Medicine

• Purpose: The Medical Student Admissions Interview Committee (MSAIC) at Wayne State University School of Medicine (WSUSOM) conducts over 1500 interviews per year. Medical student interviews are a core component of the admissions process, along with faculty/alumni interviews and multiple-mini-interviews. The continuous quality improvement (CQI) subcommittee of MSAIC aids in identifying, improving, and managing compliance. Following suggestions provided by a CQI survey about perceptions of the …

Staged Laser Interstitial Thermal Therapy For The Surgical Treatment Of Insular Glioma: A Case Series, Bhargav Ayloo, Ian Y. Lee Md, Hassan Fadel Md, Adam Robin Md, Kelly Shaftel Md, Jacob Pawloski Md, Sameah Haider Md

Medical Student Research Symposium

Staged Laser Interstitial Thermal Therapy for the Surgical Treatment of Insular Glioma: a Case Series

Introduction

Insular gliomas pose one of the most significant challenges in neurosurgical oncology due to the complexity of the surrounding functional and microvascular anatomy. Despite current surgical and technological advancements, resection of insular gliomas can lead to potentially severe neurological morbidities. Laser Interstitial Thermal Therapy (LITT), either alone or combined with surgery, presents a less invasive cytoreductive approach for treating insular gliomas.

Objective

In this work we describe the first-ever reported series of patients with insular gliomas treated with staged LITT operations with or without …

Sleep Timing And Neurocognitive Networks In Youth, Aneesh Hehr, Edward Huntley, Hilary A. Marusak

Medical Student Research Symposium

Sleep timing, particularly later midpoint of sleep, has been linked to emotion dysregulation and psychopathology. Prior adult studies link poor sleep (e.g., shorter duration, later midpoint), to altered resting-state functional connectivity (rs-FC) within and between key neurocognitive networks, particularly the default mode network (DMN), which is involved in internal thought and rumination. Importantly, many psychiatric disorders begin during adolescence, a period of shifted sleep schedules. We explored associations between midpoint of sleep and rs-FC of the DMN and other core neurocognitive networks in youth. Sleep timing was measured in 3,798 youth (11.9±0.6 years, 47.5% female) from the Adolescent Brain Cognitive …

Replacing Adjunctive Medications For Treatment-Resistant Depression Using Repetitive Transcranial Magnetic Stimulation: Case Report, Anita Vaishampayan Bs, Bassem Saad Md, Daniel Amarasinghe Bs, Carly Brin Lmsw, Richard Balon Md, Nicholas Mischel Mdphd

Medical Student Research Symposium

Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for depression. As the left prefrontal cortex activity is linked to depression, rTMS induces blood flow in the left dorsolateral prefrontal cortex (dlPFC). Long acting psychostimulants are sometimes prescribed as an adjunctive antidepressant treatment throughout rTMS therapy. We used rTMS to treat resistant depression in a middle-aged male patient over a twelve month period where a psychostimulant medication was also discontinued. He had been consistently taking duloxetine 60 mg BID, clonazepam 0.5 mg BID, and dextroamphetamine-amphetamine extended release 30 mg once daily prior to the onset of rTMS treatment. The patient …

Promis Mcid And Scb Achievement In Rotator Cuff Repair, Nikhil Yedulla, Joseph S. Tramer, Alexander Ziedas, Sreten Franovic, Mit Patel, Stephanie Muh, Eric C. Makhni

Medical Student Research Symposium

The purpose of this study was to establish threshold score changes to determine minimal clinically important difference (MCID) and substantial clinical benefit (SCB) in PROMIS computer adaptive test (CAT) scores following rotator cuff repair (RCR). Patients undergoing arthroscopic RCR were identified over a 24-month period. PROMIS CAT forms for upper extremity physical function (PROMIS-UE), pain interference (PROMIS-PI), and depression (PROMIS-D) were utilized. Analysis of variance testing with post hoc least significant difference pairwise comparisons and Tukey’s B subset analysis were used in determining if anchor question responses showed statistically significant differences between answers. These findings were used to establish two …

Factors Associated With Suicide Mortality Among Childbearing-Aged Individuals: A Case-Control Study, Katerina A. Furman, Amy Loree Phd, Leah Hecht Phd, Katerina Furman Md Candidate, Lyuba Gavrilova Bs, Hsueh-Han Yeh Phd, Catherine Frank Md, Brian Ahmedani Phd

Medical Student Research Symposium

Purpose: Examine pregnancy-related, demographic, psychosocial and healthcare utilization factors among childbearing-aged individuals who were pregnant, postpartum or who experienced pregnancy loss

Methods: Data from nine health care systems in the Mental Health Research Network was included in this sample. A case-control study design was used in which 290 childbearing-age individuals who died by suicide (cases) from 2000-2015 were matched with 10 childbearing-age individuals from the same healthcare system and enrolled during the same time period who did not die by suicide (n=2,900). Conditional logistic regression was used to analyze associations between pregnancy/postpartum/pregnancy loss status and suicide.

Results: …

Effects Of The Covid-19 Pandemic On Physical Activity In Children: A Systematic Rapid Review, Alex Ramirez B.S., Ashley Rapp Mph, Abigail C. Radomsky B.S., Sara Santarossa Phd

Medical Student Research Symposium

Background: Prolonged lockdowns, put in place to mitigate the spread of COVID-19, may have altered physical activity (PA). The goal of this systematic rapid review was to synthesize the global impact of the COVID-19 pandemic on PA of children.

Methods: Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were used to conduct a database search on 03/29/2021. Included studies were peer- reviewed, in English language, and encompassed both a measure of PA during the COVID-19 pandemic and PA data for children aged 18 and younger. The database search yielded 677 unique citations and, ultimately, 69 articles were included …

The Role Of Vigorous And High Intensity Interval Training Physical Activity Counseling In Prenatal Care, Emily Lau, Brendan T. Lynch, Sonia Hassan

Medical Student Research Symposium

Background: Physical activity is becoming a more common component of preventative medicine and patient counseling; however, the prevalence of physical activity counseling and specific social determinants of health have prevented women, namely prenatal patients, from receiving this counseling from their providers¹. Physical activity, including high intensity interval training (HIIT), has been shown to be feasible for implementation in patient counseling³ and shown to be safe for pregnant women, even into the third trimester². We hypothesize that the current percentage of patients, including prenatal patients, being counseled on physical activity is lacking. In addition, we hypothesize …

Effects Of Michigan Opioid Laws On Prescriber Practices In The Emergency Department, Lydia Ross, Gary Kanner, Claire Pearson

Medical Student Research Symposium

Introduction: Opiate analgesics (OA) are responsible for more overdose deaths than any other medication class. Michigan is among the states most greatly affected by the opioid epidemic, and in late 2017, the Michigan Opioid Laws were passed in efforts to decrease opioid associated addiction and overdose deaths. This set of laws provides regulation of OA prescriptions and to increase patient awareness of the associated risks of opioid use. These laws collectively require a physician to educate the patient on harms of opiates, provide substance abuse disorder services in the setting of an overdose, establish a relationship with the patient, obtain …

Hip Disarticulation In Wound Care: A Case Series, Kara Klomparens, Fuad Abbas, Sway Lamaj, Naveen Rehman, Richard Simman Md

Medical Student Research Symposium

Introduction

Hip disarticulation (HD) is a radical lower extremity amputation performed by carefully transecting all muscles and nerves surrounding the hip joint and separating the leg at the joint capsule. This procedure accounts for only 0.5% of all lower extremity amputations in the United States. It is generally performed due to malignant tumors, trauma and limb ischemia. However, it also has a role to play in wound care including management of severe lower extremity infections. It is considered a last resort to be used as a life-preserving measure under emergent circumstances due to high rates of morbidity and mortality.

Cases …

Multivisceral Transplant Prognosis And Complications In Patients With Metastatic Neuroendocrine Tumor, Austin Mueller, Syed-Mohammed Jafri

Medical Student Research Symposium

Neuroendocrine tumors (NETs) are a rare subset of cancers that most commonly arise in the gastrointestinal tract, but can also arise in the pancreas, lungs, ovaries, thyroid, pituitary gland, and adrenal gland. When patients present with metastatic NETs, physicians have a variety of therapeutic options. Considering these options, transplant specialists are often involved due to the profound therapeutic effects of multi-organ transplantation. However, little information is available on prognosis/complications for patients that receive multi-organ transplants due to severe metastatic NETs.

With the incidence of NETs in the United States trending in an upward direction, researchers and physicians must understand the …

Differences In Depth Of Soft Tissue At The Proximal Tibia Intraosseous Catheter Insertion Site Based On Sex And Bmi, Thomas Sprys-Tellner, John Kulka

Medical Student Research Symposium

Introduction

Intraosseous (IO) cannulation is commonly used for emergent vascular access in unstable patients treated in the emergency department (ED). However, inappropriate depth of IO insertion may be associated with increased risk of complications associated with IO catheter use, including extravasation and subsequent compartment syndrome. Our objective was to characterize the thickness of soft tissue overlying the proximal tibial IO insertion site according to patient sex, body mass index (BMI), and common medical comorbidities.

Methods

Retrospective chart review was performed for patients who received x-ray imaging of the proximal tibia at the study site. Patients were excluded if they had …

Histological Changes Of Bronchopulmonary Dysplasia And Pulmonary Hypertension: An Autopsy Series Of 42 Preterm Infants, Amelia Stone Md, Janet Poulik Md, Sara I. Koussa, Y Xin, A Sharma, Beena Sood Md, Ms

Medical Student Research Symposium

Background: Bronchopulmonary Dysplasia (BPD), a significant cause of perinatal morbidity and mortality, leads to disrupted pulmonary vascular growth and ultimately pulmonary hypertension (PH). The diagnosis of BPD is made by oxygen requirement for at least first 28 days of life. We hypothesized that histologic changes of BPD are evident before 28 days of age.

Methods: All live born preterm infants born <37 weeks of gestational age (GA), who received an autopsy between 2010 and 2017 at Children’s Hospital of Michigan or Hutzel Women’s Hospital, were identified by autopsy records. Infants with major congenital defects were excluded. Clinical data were extracted from electronic medical records. Autopsy specimens of lung and heart tissue were examined by a single pathologist, and classified according to presence or absence of defining features of BPD and PH.

Results: Of the 42 preterm infants that met the study criteria, 79% were <32 weeks GA, 55% were male, 55% were African American, 33% were SGA, and 17% were twins. Infants that died at <28 days of life were statistically more likely to be African American and receiving high frequency ventilation and were less likely to have preterm premature rupture of membranes (PPROM) and an echocardiogram obtained as part of their clinical workup.

Of infants <32 weeks GA, 61% died at <28 days of age; histological BPD was observed in 25% of infants and PH was observed in 65%. Of infants <32 weeks GA, 39% died at ≥28 days; histological BPD was observed in 92% and histological PH was observed in 85% of subjects.

Of infants ≥32 weeks GA, 78% died at <28 days of age; histological BPD was observed in 0% of infants and PH was observed in 71%. Of infants ≥32 weeks GA, 22% died at ≥28 days; histological BPD and PH were both observed in 50% of subjects.

Histological changes of BPD observed in 5 infants born <32 weeks GA who died before 28 days of age were identified as early as 6.73 days of age. Histologic PH was identified in 4 of the 5 infants with the earliest evidence being observed in an infant that died at 6.73 days of age.

Conclusion: Histologic changes consistent with BPD …

A Retrospective Chart Review Analyzing The Relationship Between Blood Pressure Rechecks And Polypharmacy, Callie M. Bartkowiak, Meghan K. Gwinn, Danielle Heidemann

Medical Student Research Symposium

ABSTRACT BODY:

Background: Hypertension (HTN) affects nearly 80 million people in the United States. A patient’s blood pressure (BP) measurement may influence the number of antihypertensives prescribed. Providers often do not recheck BP when a patient’s measurement is elevated despite research supporting that remeasuring may result in a significant decrease in BP. We hypothesized that patients who have BP remeasured in clinic would have lower BP values and thus less antihypertensive medication. In our academic general internal medicine (GIM) clinic, providers are encouraged to manually repeat BP if elevated on vitals taken by medical assistants using an automated cuff at …

Investigating The Cost-Effectiveness Of Various Distal Radius Fracture Treatments, Sreten Franovic, Alexander Pietroski, Katherine Druskovich, Brendan Page, Gabriel Burdick, Michael J. Mcintosh, Elizabeth King Md, Stephanie J. Muh Md

Medical Student Research Symposium

No abstract provided.

A Rare Case Of Deep Vein Thrombosis Secondary To Protein S Deficiency And Antithrombin Iii Deficiency With Mthfr (C677t) Heterozygous Mutation, And Crohn’S Disease, Anusha Garg, Vanama Lakshman Sai, Ankit Singh, Aditi Rao

Digital Journal of Clinical Medicine

Deep vein thrombosis is a condition wherein a thrombus develops in the deep veins of the body, most commonly in the legs, due to increasing tendency of the blood to coagulate. One such reason is the MTHFR gene mutation, wherein an increase in homocysteine levels causes irritation of the blood vessel endothelium, causing a disturbance in Virchow’s triad, hence triggering clot formation. [1]

The MTHFR gene is responsible for instructing the body to produce an enzyme called methylene tetrahydrofolate reductase(MTHFR) [2]. MTHFR gene mutations can lead to a wide range of disorders, either as a result of the elevated levels …

Multiple System Atrophy: Case Of Atypicalparkinson With Parkinson Predominant Presentation And Progressive Cerebellar Degeneration With Extrapyramidal And Autonomic Involvement, Aayushi Sharma

Digital Journal of Clinical Medicine

ABSTRACT

BACKGROUND

Multiple System Atrophy is a rapidly progressive neurodegenerative disease. Symptoms tend to appear in 50s and advance rapidly over the course of 5-10 years with progressive loss of motor and autonomic function.

Some of the common symptoms include frequent falls with or without tremors and b/l akinetic rigidity with involvement of the axial muscles. Postural tremor, severe stridor and cranio cervical dystonia may be seen. Alpha synnuclenopathies are generally characterized by REM behavioral disorders and severe dysautonomia years before the onset of the disease.

Individuals with MSA typically do not have sustained improvement in their symptoms with levodopa. …

Association Of Physical Activity And Screen Time Usage Of Adolescents In Rural Areas Of Mysore., Aakash Pavan Kumar, Nayanabai Shabadi, Bikram Sinha Roy, Anchu R. Nath, Arun Gopi

Digital Journal of Clinical Medicine

Introduction:

In these changing times there have been increased usage of screen device due to more accessibility to both device and the internet and a greater number of children are having reduced physical activity. The purpose of the current study was to determine if screen usage among adolescents (11-17yrs) who live in supportive environments is associated with decreased levels of moderate to vigorous physical activity.

Methods & materials:

A school-based cross-sectional study was conducted in two rural schools of Mysore, Karnataka in February 2023, in 176 students between the age group of 11 – 17yrs. Physical activity and screen …

Library Notes & Quotes, V1i1, Ctr Library Faculty & Staff

Library Notes and Quotes

Contents:

• Renovations & Relocations
• Study Space
• Ask a Librarian
• From the Stacks: cranes
• Book Review: Charming Billy

Equity And Diversity Minutes 03/21/2023, Equity And Diversity Committee

Equity and Diversity Committee

No abstract provided.

March 21, 2023, University Of Mississippi. Faculty Senate

Meeting Minutes

Minutes for the March 21, 2023 meeting of the University of Mississippi Faculty Senate.

March 21, 2023, University Of Mississippi. Faculty Senate

Meeting Agendas

Agenda for the March 21, 2023 meeting of the University of Mississippi Faculty Senate.

President D. Michael Lindsay Speaks At Mackenzie University In Sao Paulo, Brazil, Taylor University

2023 Website News Stories

No abstract provided.

Prominent Size Effects Without A Depolarization Field Observed In Ultrathin Ferroelectric Oxide Membranes, Haoying Sun, Jiahui Gu, Yongqiang Li, Tula R. Paudel, Di Liu, Jierong Wang, Yipeng Zang, Chengyi Gu, Jiangfeng Yang, Wenjie Sun, Zhengbin Gu, Evgeny Y. Tsymbal, Junming Liu, Houbing Huang, Di Wu, Yuefeng Nie

Department of Physics and Astronomy: Faculty Publications

The increasing miniaturization of electronics requires a better understanding of material properties at the nanoscale. Many studies have shown that there is a ferroelectric size limit in oxides, below which the ferroelectricity will be strongly suppressed due to the depolarization field, and whether such a limit still exists in the absence of the depolarization field remains unclear. Here, by applying uniaxial strain, we obtain pure in-plane polarized ferroelectricity in ultrathin SrTiO₃ membranes, providing a clean system with high tunability to explore ferroelectric size effects especially the thickness-dependent ferroelectric instability with no depolarization field. Surprisingly, the domain size, ferroelectric transition …

The Minutes Of The Marshall University Board Of Governors Meeting, March 21, 2023, Marshall University Board Of Governors

Board of Governors Minutes

No abstract provided.

Uc Personnel Committee Minutes 2023-03-21, Northern Illinois University

University Council Archives

No abstract provided.

Uc Personnel Committee Agenda 2023-03-21, Northern Illinois University

University Council Archives

No abstract provided.

Federated Learning Framework Integrating Refined Cnn And Deep Regression Forests, Daniel Nolte, Omid Bazgir, Souparno Ghosh, Ranadip Pal

Department of Statistics: Faculty Publications

Predictive learning from medical data incurs additional challenge due to concerns over privacy and security of personal data. Federated learning, intentionally structured to preserve high level of privacy, is emerging to be an attractive way to generate cross-silo predictions in medical scenarios. However, the impact of severe population-level heterogeneity on federated learners is not well explored. In this article, we propose a methodology to detect presence of population heterogeneity in federated settings and propose a solution to handle such heterogeneity by developing a federated version of Deep Regression Forests. Additionally, we demonstrate that the recently conceptualized REpresentation of Features as …

Federated Learning Framework Integrating Refined Cnn And Deep Regression Forests, Daniel Nolte, Omid Bazgir, Souparno Ghosh, Ranadip Pal

Department of Statistics: Faculty Publications

Predictive learning from medical data incurs additional challenge due to concerns over privacy and security of personal data. Federated learning, intentionally structured to preserve high level of privacy, is emerging to be an attractive way to generate cross-silo predictions in medical scenarios. However, the impact of severe population-level heterogeneity on federated learners is not well explored. In this article, we propose a methodology to detect presence of population heterogeneity in federated settings and propose a solution to handle such heterogeneity by developing a federated version of Deep Regression Forests. Additionally, we demonstrate that the recently conceptualized REpresentation of Features as …