Digital Commons Network^™

Maintenance Of Chronicity Signatures In Fibroblasts Isolated From Recessive Dystrophic Epidermolysis Bullosa Chronic Wound Dressings Under Culture Conditions, Cristian De Gregorio, Evelyng Catalán, Gabriel Garrido, Pilar Morandé, Jimena Castillo Bennett, Catalina Muñoz, Glenda Cofré, Ya-Lin Huang, Bárbara Cuadra, Paola Murgas, Margarita Calvo, Fernando Altermatt, María Joao Yubero, Francis Palisson, Andrew P. South, Marcelo Ezquer, Ignacia Fuentes

Department of Dermatology and Cutaneous Biology Faculty Papers

BACKGROUND: Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a rare inherited skin disease caused by variants in the COL7A1 gene, coding for type VII collagen (C7), an important component of anchoring fibrils in the basement membrane of the epidermis. RDEB patients suffer from skin fragility starting with blister formation and evolving into chronic wounds, inflammation and skin fibrosis, with a high risk of developing aggressive skin carcinomas. Restricted therapeutic options are limited by the lack of in vitro models of defective wound healing in RDEB patients.

RESULTS: In order to explore a more efficient, non-invasive in vitro model for RDEB studies, …

Space Efficiency By Way Of Modular Furniture: Working From Home In An Era Of Shrinking Housing, Robert Deane

Theses

In the current housing market, rental prices are increasing and the size of apartments are shrinking. This combined with increased demand from increasing urbanization and jobs moving to work-from-home arrangements, renters face challenges in fitting their lives into their smaller living spaces. One of the most common challenges reported is a lack of working space in the home. As a means to address this, I designed a system of modular parts that can be built into a variety of desks, providing a customizable work-from-home environment. The system will allow consumers to purchase precisely what they need or can afford, with …

The Tower: An Act-Based Product System That Helps Porn Addicts Eliminate Shame And Develop Healthier Habits Aligned With Their Core Values., Adetayo E. Oke

Theses

Pornography is a media phenomenon that has either educated or plagued the minds of young adolescence and teens, the topics that involve sex. Stated in a paper with (Lewczuk, K) [pornography usage has seen a rapid three times increase]; “(310%) between October 2004 and October 2016–starting from an estimated 2.76 million in the first period to 8.54 million.” The rise of pornography usage has thus caused new cases of Porn Addiction. What may seem like harmless addiction, pornography identifies as a new drug consumed by heterosexual men, and some women primarily consume it. According to studies, from (Kuer 90.1.), people …

Enhancing Small And Medium-Sized Enterprises' Performance Through The Implementation Of Erp Systems, Fatimah El Chediak

Theses

Small and medium-sized businesses (SMEs) have recognized enterprise resource planning (ERP) systems as vital for enhancing organizational efficiency, decision-making processes, and overall competitiveness. However, the effective implementation of these systems frequently presents a variety of obstacles that can prevent the attainment of their potential benefits. The purpose of this research is to investigate the critical success factors and obstacles that influence the implementation of ERP systems in SMEs and to provide suggestions for overcoming these obstacles and optimizing ERP adoption. The study employs a mixed-methods approach, combining a comprehensive literature review with primary data collected from a survey administered to …

When Ai Moves Downstream, Frances S. Grodzinsky, Keith W. Miller, Marty J. Wolf

School of Computer Science & Engineering Faculty Publications

After computing professionals design, develop, and deploy software, what is their responsibility for subsequent uses of that software “downstream” by others? Furthermore, does it matter ethically if the software in question is considered to be artificial intelligent (AI)? The authors have previously developed a model to explore downstream accountability, called the Software Responsibility Attribution System (SRAS). In this paper, we explore three recent publications relevant to downstream accountability, and focus particularly on examples of AI software. Based on our understanding of the three papers, we suggest refinements of SRAS.

Investigation Of Magnetic Bistability For A Wider Bandwidth In Vibro-Impact Triboelectric Energy Harvesters, Qais Qaseem

Mechanical Engineering Theses

Mechanical energy from vibrations is widespread in the ambient environment. It may be harvested efficiently using triboelectric generators. Nevertheless, the harvesters' effectiveness is restricted because of the limited bandwidth. This thesis proposed a comprehensive theoretical and experimental investigation of a variable frequency energy harvester, which integrates a Vibro-impact triboelectric-based harvester and magnetic nonlinearity to increase the operation bandwidth and improve the efficiency of conventional triboelectric harvesters. A cantilever beam with a tip magnet is aligned with another fixed magnet at the same polarity to induce a nonlinear magnetic repulsive force. A triboelectric harvester is integrated into the system by utilizing …

Helminth Parasites Of The Giant Toad, Rhinella Horribilis (Wiegmann, 1833) (Anura: Bufonidae) From Central Mexico, Jorge Falcón-Ordaz, Cristian Raúl Olvera-Olvera, Marisol Moreno-Chávez, Griselda Pulido-Flores, Scott Monks, Luis García-Prieto

MANTER: Journal of Parasite Biodiversity

As part of an ongoing project to inventory the helminth parasites of amphibians from the state of Hidalgo, Central Mexico, specimens of Rhinella horribilis were collected from three municipalities: Eloxochitlán, Huehuetla, and San Felipe Orizatlán. A total of eight taxa of helminths were found: three digeneans (Haematoloechus sp., Langeronia macrocirra, and Mesocoelium danforthi) and five nematodes (Cosmocerca sp., Cruzia morleyi, Ochoterenella chiapensis, Oswaldocruzia subauricularis, and Rhabdias sp.). The highest species richness was recorded in Huehuetla. All reports of these species of helminths represent new locality records for Mexico.

Transposable Elements Are Associated With The Variable Response To Influenza Infection., Xun Chen, Alain Pacis, Katherine A Aracena, Saideep Gona, Tony Kwan, Cristian Groza, Yen Lung Lin, Renata Sindeaux, Vania Yotova, Albena Pramatarova, Marie-Michelle Simon, T Pastinen, Luis B. Barreiro, Guillaume Bourque

Manuscripts, Articles, Book Chapters and Other Papers

Influenza A virus (IAV) infections are frequent every year and result in a range of disease severity. Here, we wanted to explore the potential contribution of transposable elements (TEs) to the variable human immune response. Transcriptome profiling in monocyte-derived macrophages from 39 individuals following IAV infection revealed significant inter-individual variation in viral load post-infection. Using transposase-accessible chromatin using sequencing (ATAC-seq), we identified a set of TE families with either enhanced or reduced accessibility upon infection. Of the enhanced families, 15 showed high variability between individuals and had distinct epigenetic profiles. Motif analysis showed an association with known immune regulators (e.g., …

North Central Extension Risk Management Education Center Helps Producers Manage Risks, Christine Lockert, Sheila Aikanathan Johnson, Bradley D. Lubben

Cornhusker Economics

The Extension Risk Management Education (ERME) program, funded by USDA's National Institute of Food and Agriculture, provides training to help producers learn new strategies to manage complex and growing agricultural risks. ERME strives to achieve this goal by encouraging and funding innovative programs across the country and helping programs focus on tangible results. Four regional grant-making ERME Centers are located across the country at the University of Delaware (Northeast), the University of Arkansas (South), Washington State University (West) and the University of Nebraska-Lincoln (North Central) along with a Digital Center at the University of Minnesota to help administer online application, …

Exploring The Antikythera Mechanism Through Augmented Reality., Tiffany Hatzidimitriu

Honors College Theses

The Antikythera mechanism is the oldest known analogue computer. Discovered off the coast of the Greek island of Antikythera, the Antikythera mechanism predicts and displays the position of astronomical bodies as well as astronomical phenomena. Due to its complexity, visualization of the gears movement can be very difficult. For my project I created an interactive Augmented Reality (AR) model of the Antikythera mechanism using Unity game engine. I hope this AR application exposes people to the Antikythera mechanism and its inner workings.

Meeting 2023-05-10, Civil Service Senate

Civil Service Senate Minutes

Minutes of the Civil Service Senate Meeting.

Weight Change In College Freshmen: Personal, Interpersonal And Situational Influences, Kristin L. Kuhlmann

Dissertations

Obesity has become the most significant noninfectious health risk in the United States, and the major causes of death and disability are shifting to chronic, non-communicable health conditions that are largely attributable to physical inactivity, overweight and obesity, and other diet-related factors. Among children and adolescents, the overweight/obesity rate is approaching 32%, with 17.9% of adolescents becoming obese. While the obesity rate has doubled in all age groups in the United States, it has tripled among young adults aged 18 to 28 years, and 70% of adolescents who are at a healthy weight will become overweight or obese as adults. …

Multicultural Analysis Of Topic And Emotion Drift On Youtube’S Recommendation System, Ugochukwu Olaitan Peter Onyepunuka

Theses and Dissertations

YouTube serves as a primary information source for many users, with its recommendation algorithm playing a vital role in video discovery and viewership on the platform. It determines what users are exposed to and is responsible for a significant portion (70%) of the content users engage with on the platform. It is therefore crucial to scrutinize recommendation systems to understand potential algorithmic biases that may spread disinformation. Previous studies have shown that the recommendation algorithm favors a small number of videos, creating mild ideological echo chambers. This study aims to investigate the extent to which YouTube's recommendation algorithm spreads disinformation …

"Making Munitions Is Woman's Job" Working In Connecticut Munitions Factories: Wwi Propaganda Campaigns, Karen E. Gionet Zentek

Theses and Dissertations

In this thesis, I describe the government agencies that were created to develop propaganda advertisements geared to pressure Connecticut women into working in munitions factories during World War I, focusing specifically on Bridgeport. I deconstruct some of the images and rhetorical strategies used to create the “Making Munitions is Woman’s Job” newspaper advertisements, including the “Minute Women of Bridgeport” recruitment effort, both published in the Bridgeport Times and Evening Farmer newspaper.

Newsroom, Georgia Southern University

Newsroom (2006-2023)

TEDxSavannah to Inspire, Spark Discussion on Georgia Southern’s Armstrong Campus May 25

Afrikaans to English: Gabi Wiggill Discovers Globalist View, Joy at the Intersection of Medicine, Science and Law

Life lessons, Followed by a Six-and-a-Half-Year Degree: Jonathan Hoopaugh Catapults from Academic Suspension to Graduating with Honors

Mechanical Engineering Graduate’s Dedication to Research Paves Way for Ph.D. Pursuit

Physician Views On The Provision Of Information On Immune Checkpoint Inhibitor Therapy To Patients With Cancer And Pre-Existing Autoimmune Disease: A Qualitative Study, Maria A Lopez-Olivo, Gabrielle F Duhon, Juan I Ruiz, Mehmet Altan, Hussein Tawbi, Adi Diab, Clifton O Bingham, Cassandra Calabrese, Natalia I Heredia, Robert J Volk, Maria E Suarez-Almazor

Faculty, Staff and Student Publications

Immune checkpoint inhibitors (ICIs) have improved cancer outcomes but can cause severe immune-related adverse events (irAEs) and flares of autoimmune conditions in cancer patients with pre-existing autoimmune disease. The objective of this study was to identify the information physicians perceived as most useful for these patients when discussing treatment initiation with ICIs. Twenty physicians at a cancer institution with experience in the treatment of irAEs were interviewed. Qualitative thematic analysis was performed to organize and interpret data. The physicians were 11 medical oncologists and 9 non-oncology specialists. The following themes were identified: (1) current methods used by physicians to provide …

Los Pedrenses: Alternative Tourism, The Spectacle Of Youth, And Struggles For Local Authority In La Pedrera, Uruguay, Gwendelyn Gardner

Honors Theses

Tourism has been a longstanding industry in La Pedrera, a rural beach town along the Atlantic coast of Rocha, Uruguay. The effects of recent forms of tourism massification in the form of los boliches and Carnaval have prompted residents to develop a local discourse and sociopolitical front against youth and mass tourism. This discourse has roots in the strong connection between residents and the environment that has shaped the development of the community as caretakers of the region. Such reasoning is based on interviews with La Pedrera locals, social media analysis, and articles for local and national newspapers in conjunction …

The Engineering Challenges Of Designing And Manufacturing A Tensegrity Cup Stand, Yaniv Goulet, Daniel Ferro

Honors Theses

Progressing from a simple idea into a fully developed product is one of the main goals of any engineer. Through Haley Barbour Center for Manufacturing Excellence’s capstone program, the team was tasked with realizing a tensegrity cup stand. The tensegrity structure consists of a top and a bottom of some form only supporting itself by tension. The team had to research the concept, create an initial design, create a prototype of the product, improve the design after the prototype’s mistakes, apply lean principles to improve the manufacturing efficiency, and analyze all the economic impacts of the engineering decisions. In the …

The Association Between Sleep And Relationship Quality Among Undergraduate Students, Catherine Smith

Honors Theses

This study sought out to examine the association between sleep and relationship quality in undergraduate student populations. Attending university is a novel experience for emerging adults but is subsequently associated with increased sleep difficulties and increased exposure to various social relationships. Indeed, the literature suggests social relationships can influence sleep in all populations, but few have explored relationship quality in the context of conflict and support in undergraduates. The quality of different social relationships (romantic, family, and friend), the severity of insomnia symptoms, and length of sleep duration were investigated. The current study collected data from a sample of ten …

Para Todes: ¿Sí O No? The Use Of Inclusive-Language Alternatives In The Spanish Language In Montevideo, Uruguay, Gabrielle Goulet

Honors Theses

This thesis investigates the attitudes towards the possible implementation of gender-neutral language, through the use of the -e, on official documents and schools in Montevideo, Uruguay, and how the attitudes of Spanish speakers in Uruguay align with the country’s history of inclusivity. In this context, Uruguay is considered an inclusive country because there is evidence of legal changes that promote gender equality, thus creating an gender-inclusive environment. This thesis utilizes a mixed-methods approach which includes both qualitative and quantitative research. The findings show that many people will use inclusive language when asked of them. They also believe that this usage …

A Case Study Of California's Maternal Health Landscape And Recommendations For Mississippi, Kinley Miller

Honors Theses

This paper is a case study of California’s maternal health landscape, reflecting its exceptional approach to the maternal health crisis. I review several policies: the creation of the Maternal Quality Care Collaborative, the Maternal Data Center, and the Maternal Mortality Review Committee, maternal health toolkits, Medicaid expansion, extended postpartum Medicaid coverage, paid family leave, C-Section Honor Roll, and maternal mental health measures. The case study suggests that all of these policies in conjunction with one another correlates with a decrease maternal mortality. California’s proactive approach and ability to mobilize public and private entities are key attributors to its success in …

Ms. Eep's Compass: A Hope-Filled Story Inspired By A Trauma-Informed Teaching Framework, Sadie Stocks

Honors Theses

This thesis examines the literature on childhood trauma, its manifestations in the classroom, and effective trauma-informed teaching practices. The literature indicates the widespread prevalence of Adverse Childhood Experiences (ACEs) and the consequences these experiences have on both the developing brains of children and future health risks. While drawing the correlation of this widespread trauma to its common manifestations in the classroom, Maslow’s Hierarchy of Needs further justifies the indispensable link of safety preceding learning. Trauma-Informed teaching practices include environmental considerations like safety, the value of relationship building, a strengths-based guided classroom, models of self-regulation, developmentally appropriate practice, and an emphasis …

From Concept To Completion: The Multifaceted Process Of Designing, Manufacturing, And Problem-Solving In The Development Of A Horizontal Bumper Plate Rack, Wallace Crain

Honors Theses

The purpose of this thesis was to create a bumper plate organizer from concept to final production run to simulate what it would be like to create a new product. The entire Center for Manufacturing Excellence coursework led up to this moment where all of the coursework could be put into practical use. The project began in Spring 2022 and finished in Fall 2022. The team was made of one mechanical engineering major, one civil engineering major, one biology major, one computer science major, and one accounting major. My main focus in this project was on the product design and …

Effects Of Group Ii Metal Binding On The Stability Of Dna I-Motif Structures, Charlotte Powers

Honors Theses

B-form DNA can adopt alternative structures while in superhelical duress. Alternative DNA structures are favored when there is an asymmetric distribution on complementary DNA strands. Cytosine rich strands may utilize cytosine-cytosine base pairing to form a four-stranded structure known as the i-motif (iM). The stability of iMs is affected by several factors such as DNA sequence, temperature, pH, ionic strength of the solution, and crowded conditions. While the effects of temperature, pH, and crowding conditions on iM stability have been well documented, the effects of ion presence in a solution has been less studied. Hence, those studies are the basis …

Anticoagulant And Anti-Sars-Cov-2 Effects Of Botryocladia Occidentalis Sulfated Glycans, Reena Thara

Honors Theses

Marine algal species are composed of various macromolecules endowed with potential biological actions, such as carbohydrates. Sugars are complex in nature with a multitude of monosaccharides constructed into polymers. We call complex carbohydrate polysaccharides those of great structural variation. The sulfation pattern adds to their complexity, creating scientific interest in the aquatic organisms from which these molecules can be extracted. Sulfated polysaccharides are now increasingly studied for their potential biological properties as anticoagulants and as antivirals. Heparin is a naturally occurring sugar in the human body that is necessary for proper anticoagulation. Many people today suffer from a dysfunctional coagulation …

Financial Accounting Case Studies, Winn Sams

Honors Theses

This thesis is an assembly of eleven accounting case studies completed during the 2021-2022 academic year, while enrolled in the ACCY 420 course instructed by Dr. Victoria Dickinson. The case studies included in this thesis cover a broad range of topics within the field of accounting. These topics include the impact of the September 11, 2001, terrorist attacks on businesses, the financial effects of COVID-19 on Pfizer Inc., examining cities of future residence for accounting careers, an interview with a business owner, and an Excel verification course. Cases 6 through 11 are dedicated to the analysis of ExxonMobil and its …

The Great Transition: A Qualitative Examination Of The Transition From Pharmacy Student To Pharmacist, Jessica Marlee Wilson

Honors Theses

Background: Over the years, community pharmacy practice has expanded and increased the number of responsibilities pharmacists must manage. Tasks such as managing the pharmacy, counseling patients, and administering vaccines are among the duties that pharmacists must carry out. The recent Covid-19 pandemic placed a significant strain on the retail pharmacy work environment and acted as an obstacle to the jobs of community pharmacists. Recent pharmacy graduates are often thrown into this variable work environment, and it seems that there is limited literature regarding the preparedness that they feel in this area of pharmacy work.

Objectives: To uncover the level of …

The New Teacher Of Ideas: A Study On Social Media, Political Influencers, And Generation Z, Brenley Rinaudo

Honors Theses

The current study focuses on members of Generation Z and where they learn about politics and receive political news. Different than previous generations, Generation Z receives news on social media more than on traditional media platforms (Murmuration, 2023). Politicians must quickly begin to understand how to engage and connect with the next generation of voters on these social media platforms. For these reasons, this study surveyed members of Generation Z at The University of Mississippi. Current University of Mississippi students are members of Generation Z and reflect common trends among this Generation, such as constant usage of social media. This …

Southern Sustainability: An Examination Of Waste Management Mechanisms Within The University Of Mississippi Community, Haley Clift

Honors Theses

The purpose of this thesis is to analyze and study local mechanisms surrounding waste management at The University of Mississippi. The research study gathers quantitative and qualitative research to make conclusions about sustainability and recycling practices on The University of Mississippi's campus. The thesis discusses whether those practices are effective for those in The University of Mississippi's community based on the data collected and research conducted. The researcher also offers proposals for the University of Mississippi community based on the research conducted.

The gap that exists in the waste management processes at The University of Mississippi was addressed by blending …

Tourism's Power To Promote Peacebuilding In Post-Conflict Societies - A Northern Ireland Case Study, Margaret Walker

Honors Theses

This thesis explores the capacity of tourism to promote peacebuilding in post-conflict societies, specifically focusing on Northern Ireland. This study assesses the current state of conflict tourism in Northern Ireland by analyzing two tourist sites and considering variables that may impact peacebuilding in the greater Northern Ireland community. It measures the success of the Northern Ireland approach by comparing the effects of tourism in other post-conflict and conflict societies. This study culminates with the presentation of certain strategies that Northern Ireland should implement to positively impact peacebuilding through tourism. Curators must portray history in a balanced, sensitive manner that avoids …