Digital Commons Network^™

Effects Of Atlantic Butterfish (Peprilus Triacanthus) In Diets Of Common Terns (Sterna Hirundo): A Case Study Of Climate Change Effects In The Gulf Of Maine, Olivia A. Smith, Elizabeth C. Craig

Faculty Publications

Climate change and associated shifts in marine prey communities can alter food availability for foraging seabirds. This issue is illustrated in the Gulf of Maine by the northward shift of Atlantic butterfish (Peprilus triacanthus; hereafter butterfish) and their subsequent increase in seabird diets. Here, we examine effects of butterfish in diets of the Common Tern (Sterna hirundo), a threatened species in this region. Our objectives were to evaluate butterfish suitability for tern chick diet through observing handling time and feeding success, to examine effects of butterfish on tern chick growth, and to explore signs of adaptive foraging in adults. The …

Psychometric Properties And Refinement Of The Att-Ipv Scale To Measure Attitudes About Intimate Partner Violence Among Married Adolescents And Their Husbands In Niger, Ruvani W. Fonseka, Sneha Challa, Jay G. Silverman

Faculty Research, Scholarly, and Creative Activity

(1) Background: This study sought to assess the appropriateness of a five-item scale to measure attitudes towards IPV (ATT-IPV) among married adolescent girls and their husbands in Niger, a population in which this scale has not yet been tested. (2) Methods: Using data collected from 1100 pairs of married adolescents, aged 13–19 years old, and their husbands across 48 villages in rural Niger, we performed classical test theory reliability and exploratory factor analysis, followed by item response theory (IRT) analyses and testing differential item functioning (DIF) by gender. (3) Results: The ATT-IPV scale was found to be internally consistent (alpha …

Christina Van Dyke, A Hidden Wisdom: Medieval Contemplatives On Self-Knowledge, Reason, Love, Persons, And Immortality, Amber L. Griffioen

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Skeleton Weed In Western Australia: Management Guide, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity bulletins

Skeleton weed can reduce crop yields by competing for moisture and nutrients (mainly nitrogen). This guide helps you manage and eradicate skeleton weed infestations on your property, and helps to stop the spread across WA.

Without the coordinated program aimed at controlling the spread, skeleton weed would now be much more abundant and widely established throughout cereal growing areas.

Industry Funding Scheme (grains, seeds and hay)

The Grains, Seeds and Hay Industry Funding Scheme is overseen by a seven-member Industry Management Committee. These 2 groups are comprised of producers and others with an interest in the industry. They meet in …

Measurements Of Ear-Canal Geometry From High-Resolution Ct Scans Of Human Adult Ears, Auden P. Balouch, Karen Bekhazi, Hannah E. Durkee, Rebecca M. Farrar, Mealaktey Sok, Douglas H. Keefe, Aaron K. Remenschneider, Nicholas J. Horton, Susan E. Voss

Engineering: Faculty Publications

Description of the ear canal’s geometry is essential for describing peripheral sound flow, yet physical measurements of the canal’s geometry are lacking and recent measurements suggest that older-adult-canal areas are systematically larger than previously assumed. Methods to measure ear-canal geometry from multi-planar reconstructions of high-resolution CT images were developed and applied to 66 ears from 47 subjects, ages 18–90 years. The canal’s termination, central axis, entrance, and first bend were identified based on objective definitions, and the canal’s cross-sectional area was measured along its canal’s central axis in 1-2 mm increments. In general, left and right ears from a given …

Corporate Compliance's Achilles Heel, Miriam Baer

Faculty Scholarship

No abstract provided.

A Comparative Effectiveness Study On Opioid Use Disorder Prediction Using Artificial Intelligence And Existing Risk Models, Sajjad Fouladvand, Jeffery Talbert, Linda Phyliss Dwoskin, Heather M. Bush, Amy L. Meadows, Lars E. Peterson, Yash R. Mishra, Steven K. Roggenkamp, Fei Wang, Ramakanth Kavuluru, Jin Chen

Markey Cancer Center Faculty Publications

Opioid use disorder (OUD) is a leading cause of death in the United States placing a tremendous burden on patients, their families, and health care systems. Artificial intelligence (AI) can be harnessed with available healthcare data to produce automated OUD prediction tools. In this retrospective study, we developed AI based models for OUD prediction and showed that AI can predict OUD more effectively than existing clinical tools including the unweighted opioid risk tool (ORT). Data include 474,208 patients’ data over 10 years; 269,748 were females with an average age of 56.78 years. Cases are prescription opioid users with at least …

Emt Activates Exocytotic Rabs To Coordinate Invasion And Immunosuppression In Lung Cancer, Guan-Yu Xiao, Xiaochao Tan, Bertha L. Rodriguez, Don L. Gibbons, Shike Wang, Chao Wu, Xin Liu, Jiang Yu, Mayra E. Vasquez, Hai T. Tran, Jun Xu, William K. Russell, Cara Haymaker, Younghee Lee, Jianjun Zhang, Luisa Solis, Ignacio I. Wistuba, Jonathan M. Kurie

Markey Cancer Center Faculty Publications

Epithelial-to- mesenchymal transition (EMT) underlies immunosuppression, drug resistance, and metastasis in epithelial malignancies. However, the way in which EMT orchestrates disparate biological processes remains unclear. Here, we identify an EMT- activated vesicular trafficking network that coordinates promigratory focal adhesion dynamics with an immunosuppressive secretory program in lung adenocarcinoma (LUAD). The EMT-activating transcription factor ZEB1 drives exocytotic vesicular trafficking by relieving Rab6A, Rab8A, and guanine nucleotide exchange factors from miR-148a-dependent silencing, thereby facilitating MMP14-dependent focal adhesion turnover in LUAD cells and autotaxin-mediated CD8+ T cell exhaustion, indicating that cell- intrinsic and extrinsic processes are linked through a microRNA that coordinates vesicular …

Enhanced Bypass Of Pd-L1 Translation Reduces The Therapeutic Response To Mtor Kinase Inhibitors, Yanan Cao, Qing Ye, Murong Ma, Qing-Bai She

Markey Cancer Center Faculty Publications

Increased PD-L1 expression in cancer cells is known to enhance immunosuppression, but the mechanism underlying PD-L1 upregulation is incompletely characterized. We show that PD-L1 expression is upregulated through internal ribosomal entry site (IRES)-mediated translation upon mTORC1 inhibition. We identify an IRES element in the PD-L1 50-UTR that permits cap-independent translation and promotes continuous production of PD-L1 protein despite effective inhibition of mTORC1. eIF4A is found to be a key PD-L1 IRES-binding protein that enhances PD-L1 IRES activity and protein production in tumor cells treated with mTOR kinase inhibitors (mTORkis). Notably, treatment with mTORkis in vivo elevates PD-L1 levels and reduces …

Integrative Analysis Of Mendelian Randomization And Gene Expression Profiles Reveals A Null Causal Relationship Between Adiponectin And Diabetic Retinopathy, Ao Zhang, Hui Wu, Chi Wang, Suyan Tian

Markey Cancer Center Faculty Publications

Observational studies have been conducted to investigate the correlation between adiponectin and diabetic retinopathy (DR), but no consistent relationship has been established. In this study, we employed an integrative analysis that combined Mendelian randomization (MR) and bioinformatics analyses to comprehensively explore the association between DR and adiponectin, aiming to provide a unified answer of their relationship. Using the inverse-variance weighted (IVW) method, the odd ratio (OR) of developing DR per 1 mg/dL increment in genetically predicted log- transformed adiponectin concentration was estimated to be 0.949 (P = 0.557). Other robust MR methods produced consistent results, confirming the absence of a …

Lung And Colorectal Cancer Disparities In Appalachian Kentucky: Spatial Analysis On The Influence Of Education And Literacy, Nicole Robertson Mph, Todd Burus, Lauren Hudson, Pamela C. Hull, Lee Park, Nathan L. Vanderford

Markey Cancer Center Faculty Publications

Low educational attainment and high cancer incidence and mortality rates have long been a challenge in Appalachian Kentucky. Prior studies have reported disparities in cancer incidence and mortality between Appalachian and non-Appalachian populations, but the influence of education on this disparity has not been extensively studied. Herein, all cancers and two cancer sites with available screenings (colorectal and lung) were joined with education indicators (educational attainment and literacy) and one geographic indicator across all 120 Kentucky counties. This dataset was used to build choropleth maps and perform simple linear and spatial regression to assess statistical significance and to measure the …

Messes: Software For Transforming Messy Research Datasets Into Clean Submissions To Metabolomics Workbench For Public Sharing, P. Travis Thompson, Hunter N. B. Moseley

Markey Cancer Center Faculty Publications

In recent years, the FAIR guiding principles and the broader concept of open science has grown in importance in academic research, especially as funding entities have aggressively promoted public sharing of research products. Key to public research sharing is deposition of datasets into online data repositories, but it can be a chore to transform messy unstructured data into the forms required by these repositories. To help generate Metabolomics Workbench depositions, we have developed the MESSES (Metadata from Experimental SpreadSheets Extraction System) software package, implemented in the Python 3 programming language and supported on Linux, Windows, and Mac operating systems. MESSES …

Nac1 Confines Virus‐Specific Memory Formation Of Cd4+ T Cells Through The Rock1‐Mediated Pathway, Liqing Wang, Hao-Yun Peng, Jugal Kishore Das, Anil Kumar, Yijie Ren, Darby J. Ballard, Xiaofang Xiong, Wen Yang, Xingcong Ren, Paul De Figueiredo, Jin-Ming Yang, Jianxun Song

Markey Cancer Center Faculty Publications

Nucleus accumbens‐associated protein 1 (NAC1), a transcriptional cofactor, has been found to play important roles in regulating regulatory T cells, CD8 + T cells, and antitumor immunity, but little is known about its effects on T‐cell memory. In this study, we found that NAC1 expression restricts memory formation of CD4 + T cells during viral infection. Analysis of CD4 + T cells from wild‐type (WT) and NAC1‐ deficient (−/−) mice showed that NAC1 is essential for T‐cell metabolism, including glycolysis and oxidative phosphorylation, and supports CD4 + T‐cell survival in vitro. We further demonstrated that a deficiency of NAC1 downregulates …

The Metabolomics Workbench File Status Website: A Metadata Repository Promoting Fair Principles Of Metabolomics Data, Christian D. Powell, Hunter N. B. Moseley

Markey Cancer Center Faculty Publications

Background: An updated version of the mwtab Python package for programmatic access to the Metabolomics Workbench (MetabolomicsWB) data repository was released at the beginning of 2021. Along with updating the package to match the changes to MetabolomicsWB’s ‘mwTab’ file format specification and enhancing the package’s functionality, the included validation facilities were used to detect and catalog file inconsistencies and errors across all publicly available datasets in MetabolomicsWB.

Results: The MetabolomicsWB File Status website was developed to provide continuous validation of MetabolomicsWB data files and a useful interface to all found inconsistencies and errors. This list of detectable issues/errors include format …

Becoming A Man: Concepts Of Writing Witness And Masculinity For Black Adolescent Males In Children’S And Young Adult Literature, Chelsea Danielle Rogers

Theses and Dissertations

Historically, the black male has had the world at his back, from the moment he stepped onto American soil, kidnapped and enslaved, the pressures to be a “good man” as a student or eventually as a father, to the need to “be somebody” as a proud American citizen, a human. In my dissertation, I evaluate further the position of the adolescent black male through the lens of young adult literature. The framework of a young adult novel is grounded in the experience of youth and adolescence rather than in adulthood and its nostalgic tendencies. The young black male experience and …

1, 2, 3: Counting On Problem Based Learning To Improve Mathematical Achievement In African American Students, Kelley P. Spahr

Theses and Dissertations

Mathematics is an important component of our everyday lives. It involves necessary skills, such as computation, problem solving, and critical thinking. In spite of this, a significant portion of our students are unable to demonstrate proficiency. These students are typically the underserved, marginalized students who are over represented in remedial classes and behavioral statistics (Gibson, 2022; Harper, 2010, 2021; Zilanawala, et al., 2018). This research study presented two instructional interventions, culturally relevant pedagogy and problem-based learning, to examine the impact of self-efficacy, critical thinking, and mathematical achievement. This study utilized a mixed-methods triangulation design. The participants of this study were …

Effects Of Parenting And Self-Efficacy On Diet, Family Mealtime And Weight-Related Outcomes In African American Adolescents, Haylee Michele Loncar

Theses and Dissertations

Despite substantial research and concern, adolescent overweight and obesity continues to be a significant public health problem. Theory based on developmental literature emphasizes the role of adolescent self-regulatory factors, like self-efficacy, in health behavior engagement and weight-related outcomes. There is also extensive literature that highlights parents’ role in promoting self-regulatory development through warm and responsive behaviors and practices. However, few studies have considered longitudinal associations and changes in weight-related outcomes over time, as well as moderated effects by parenting. This study assessed longitudinal associations between adolescent self-efficacy parenting factors and adolescent BMI, diet, and family mealtime to fill gaps in …

Kinerja Ekspor Indonesia: Dampak Pandemi Covid-19 Vs Perang Rusia, Samsul Arifin

Jurnal Ekonomi dan Pembangunan Indonesia

Is COVID an obstacle to Indonesia’s trade flows vs. war to boost Indonesia’s exports? Application of the Gravity model using the OLS panel data fixed effect method to address the endogeneity problem for the 2018q1–2022q3 period. The significant positive results of exporters’ and importers’ GDP and the significant negatif results of distance prove the validity of the gravity model. The significant negatif results of the COVID-19 dummy and the significant positive results of the dummy war show that Indonesia’s exports with trading partners during COVID-19 have decreased, while the impact of the war was able to encourage an increase in …

Pengaruh Pdb Per Kapita Dan Konsumsi Energi Terhadap Emisi Grk Di Indonesia, Sarwono Alfian H. Nadeak, Nasrudin Nasrudin

Jurnal Ekonomi dan Pembangunan Indonesia

The purpose of this research is to analyze the effect of GDP per capita and energy consumption on greenhouse gas emissions and test the hypothesis of the Environmental Kuznets Curve (EKC) in Indonesia. This study uses two methods, namely Error Correction Mechanism (ECM) and Autoregressive Distributed Lag (ARDL) with bound testing approach. The results showed that GDP per capita had a positive effect on greenhouse gas emissions. Renewable energy consumption negatively affects greenhouse gas emissions, while non-renewable energy consumption negatively affects total greenhouse gas emissions, but positively influences CO2 emissions. In the long run, the EKC hypothesis applies in Indonesia.

Apakah Modal Manusia Penting Untuk Mengangkat Jawa Timur Dari Jebakan Kelas Menengah?, Christiayu Natalia, Setyo Tri Wahyudi

Jurnal Ekonomi dan Pembangunan Indonesia

Optimizing demographic dividend requires human capital quality improvement. However, disparities in the quality of human capital between regions in East Java becoming challenge in increasing GRDP per capita growth before demographic bonus period ends. This research analyze the effect of human capital quality on GRDP per capita growth during 2011–2022 period generally in East Java Province and specifically in districts/cities with low human capital quality. Dynamic panel data regression analysis using the First-Difference Generalized Moment Method (FD-GMM) was used in this research. The research results show a significant influence of the quality of human capital on GDP per capita growth.

Lecture Notes On Cloud Computing (Ver. Summer 2023), Jun Li

Open Educational Resources

No abstract provided.

The Effect Of Using Data Palm Waste Fibers In Plain Concrete Mixture By Comparing Three Pre‐Treatment Techniques, Dina Rushdy M. Moawad, Rania Rushdy Moussa

Architectural Engineering

The high rates of industrial and agricultural wastes and byproduct production produced several environmental concerns in addition to increasing the risks of contaminating natural resources. The amount of organic waste has been rising over the past few decades, but it has been poorly managed, especially in smaller countries where it is either burned, improperly disposed, or thrown in landfills. Moreover, the production of concrete generates a large amount of waste that has a negative impact on our planet even though it is an extremely significant building material. The potential of developing another plain concrete mixture sample with date palm mesh …

Metabolic And Renal Outcomes Of Empagliflozin In Patients With Type 2 Diabetes Mellitus Attending Armed Forces Hospital In Saudi Arabia: Retrospective Cohort Study, Ali A. Alshahrani, Saeed M. Mashhour, Zayed S. Alkhtani, Yahya M. Alragea

Saudi Medical Journal

Objectives: To explore the effects of empagliflozin (25 mg) on metabolic and renal parameters in patients with type 2 diabetes mellitus (T2DM). Methods: This retrospective observational comparative study was conducted at a military hospital in southern Saudi Arabia. All adults (aged >18 years) with T2DM who attended diabetic clinics between October 2021 to March 2022 (6 months), with or without insulin treatment, were eligible for inclusion in the study. Results: Following the initiation of empagliflozin treatment, statistically significant reductions in patient weight (kg) were observed at 1, 3-5, and 6 months. In addition, low-density lipoprotein levels significantly decreased 3-5 months …

Does Fat Content Within Muscle Predict Risk Of Cognitive Decline?

Saudi Medical Journal

No abstract provided.

Women And Girls Bear Brunt Of Water And Sanitation Crisis – New Unicef-Who Report

Saudi Medical Journal

No abstract provided.

Multiracial Identity Integration: Components, Antecedents, And Consequences, Sheila Xi Rui Wee

Dissertations and Theses Collection (Open Access)

Existing research on multiracials has examined how multiracials develop different racial identities. However, empirical research on how multiracial manage and integrate their identities as well as its impact are limited. This dissertation examined key antecedents and consequences associated with the unique process that multiracials undergo to achieve a positive identity via Multiracial Identity Integration (MII). In Study 1, we examined the link between MII, psychological well-being, and cognitive capacity. Results revealed a positive association between MII and psychological well-being as well as some cognitive capacity outcomes. Study 2 replicated the same relationship between MII and psychological well-being/cognitive capacity outcomes. Additionally, …

No Interest In Being Cynical: Conflicting Versus Corresponding Interests Track Variability In The Link Between Personal Control And Cynicism, Bryan Kwok Cheng Choy

Dissertations and Theses Collection (Open Access)

Recent literature indicates that a lack of personal control negatively predicts (social) cynicism, a negative view of others as self-interested and exploitative (Stavrova & Ehlebracht, 2018a, 2019). Despite the ostensibly robust nature of this relationship, I propose that the strength of the link between personal control and cynicism could be more variable than extant findings have suggested. In particular, I argue that variability in the controlcynicism link may be tracked (i.e., moderated) by the extent to which actors in a situation have corresponding or conflicting interests, with the effect of control on cynicism being attenuated when actors are perceived to …

The Fear Of Being Idle: What It Is And How It Relates To Goal Pursuits, Verity Yu Qing Lua

Dissertations and Theses Collection (Open Access)

Modern society places a strong emphasis on making full use of one’s time and the aversion of idleness. While urging people to spend their time wisely can promote productivity and personal striving, an overemphasis on this ideal can also have detrimental effects on their sense of well-being. However, to date, there is limited research on individuals’ belief about aversion towards idle time – in part due to the lack of a measurement scale to assess such a disposition. Thus, the current work proposed a novel construct and measure—the fear of being idle (FOBI)—to capture the individual differences in affective responses …

Effect Of Leader-Member Exchange Social Comparison On Co-Worker’S Envy And Work Behavior Moderated By Perceived Deservingness Of Star Workers, Ronnie Ng

Dissertations and Theses Collection (Open Access)

The extant leader-member exchange (LMX) literature suggests that leaders establish and develop different quality dyadic relationships with members in the same workgroup. High-quality LMX is argued as beneficial to employees. However, studies have overlooked the emotions and behaviors of low-quality LMX employees to determine how they differ from high-quality LMX employees. This study integrates LMX differentiation literature, social comparison theory and attributional theory to examine the role of LMX social comparison (LMXSC) perceptions in triggering help-seeking and knowledge hiding from star co-workers in the workplace. This study also explores the mediating role of dual envy, that is, benign and malicious …

Eating Disorders - Medical Work-Up And Stabilization, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.