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Image Segmentation With Human-In-The-Loop In Automated De-Caking Process For Powder Bed Additive Manufacturing, Vincent Opare Addo Asare-Manu Jul 2023

Image Segmentation With Human-In-The-Loop In Automated De-Caking Process For Powder Bed Additive Manufacturing, Vincent Opare Addo Asare-Manu

Theses and Dissertations

Additive manufacturing (AM) becomes a critical technology that increases the speed and flexibility of production and reduces the lead time for high-mix, low-volume manufacturing. One of the major bottlenecks in further increasing its productivity lies around its post-processing procedures. This work focuses on tackling a critical and inevitable step in powder-bed additive manufacturing processes, i.e., powder cleaning or de-caking. Pressing concerns can be raised with human involvement when performing this task manually. Therefore, a robot-driven automatic powder cleaning system could be an alternative to reducing time consumption and increasing safety for AM operators. However, since the color and surface texture …

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Soil Moisture Dynamics In Cover Cropping Systems: From Local To Global Scales, Manish Gautam Jul 2023

Soil Moisture Dynamics In Cover Cropping Systems: From Local To Global Scales, Manish Gautam

Theses and Dissertations

Cover cropping systems, which have gained recognition for their ability to enhance soil health and promote sustainability are also associated with potential risks related with declining soil moisture and pose a dilemma for farmers considering the adoption of cover crops in water deficit semi-arid settings worldwide. To address this pressing issue, we conducted a participatory cover cropping trial in the Lower Rio Grande Valley (LRGV) region, encompassing four different farms and supplemented this experiment with a meta-analysis to answer our soil moisture and climate parameters and quantify the impact of cover crops on soil moisture levels. The findings revealed that …

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Tamaulipan Thornforest Restoration: Factors Influencing Restoration Outcomes And Impacts Of Cover Crops During Replanting, Jerald T. Garrett Jul 2023

Tamaulipan Thornforest Restoration: Factors Influencing Restoration Outcomes And Impacts Of Cover Crops During Replanting, Jerald T. Garrett

Theses and Dissertations

Though the rate of deforestation has slowed in recent years, it remains a primary cause of land cover change within forest ecosystems. The Lower Rio Grande Valley, Texas (LRGV) has lost nearly 95% of its native thornforest since the early 1900’s due to agricultural and urban expansion. The focus of this study is to assess the current vegetative state of restored thornforest sites located in the eastern LRGV and to evaluate the use of cover crops during replanting of native seedlings. Our assessment of restored thornforest sites revealed actively restored sites demonstrated higher overall averages of richness, abundance, and diversity …

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The Universality Of God In Amo’S Oracles And Creation: A Historical-Critical Approach Within A Catholic Context, Alexandra Bochte Jul 2023

The Universality Of God In Amo’S Oracles And Creation: A Historical-Critical Approach Within A Catholic Context, Alexandra Bochte

Master's Theses (2009 -)

In the Old Testament, the Israelite nation is identified as a chosen people of God and in a covenantal relationship with him. This thesis will argue that the Noahide covenantal relationship extends to more than just the Israelites such that all creation is in a covenant with the universal God. This is supported through an exploration of Ancient Near Eastern literature and its similarities with biblical stories. Exegetical analyses of Psalms and prophetic biblical literature will further demonstrate God’s universality and will elucidate what it means to be in a covenantal relationship with God. When there is relationship there must …

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Creep Resistance And Microstructure In Binary Aluminum Cerium Alloy Produced By Laser Powder Bed Fusion, Jillian Ann Stinehart Jul 2023

Creep Resistance And Microstructure In Binary Aluminum Cerium Alloy Produced By Laser Powder Bed Fusion, Jillian Ann Stinehart

Master's Theses (2009 -)

Currently, the only commercially available aluminum alloy for additive manufacturing (AM) is AlSi10Mg, which is not suitable for high temperature applications. Al-Ce based alloys have been shown to be highly printable, cost-efficient alloys. Compared to cast Al-Ce alloys, the eutectic features are refined (<1μm), which give AM Al-10Ce favorable strength and ductility at room temperature. The low diffusivity and solubility of cerium in aluminum improve the retention of mechanical properties at high temperatures. In order to quantify the effect of cerium on the thermal stability of AM aluminum and show its suitability for high-temperature applications, Al-10Ce was creep tested between 60-77% of its absolute melting temperature. The creep performance of AM Al-10Ce was favorable compared to that of cast binary Al-Ce and AM AlSi10Mg and was comparable to that of cast ternary Al-Ce alloys. The stress exponent, n, was approximately 1 in the low stress regime and 5-7 in the high stress regime. The activation energy was 231kJ/mol. In comparison, both cast binary Al-Ce and AM AlSi10Mg have higher stress exponents and lower activation energies, showing AM Al-10Ce to be more creep resistant. After creep testing, slight grain coarsening was observed, while grain orientation remained unchanged. The melt pool boundaries (MPBs) faded in appearance after creep testing, and the number of columnar grains decreased.

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Maxillary And Mandibular Incisor And Molar Dentoalveolar Heights In Untreated Subjects Presenting Class I And Class Ii Malocclusion, Samantha Zavada Cardinal Jul 2023

Maxillary And Mandibular Incisor And Molar Dentoalveolar Heights In Untreated Subjects Presenting Class I And Class Ii Malocclusion, Samantha Zavada Cardinal

Master's Theses (2009 -)

Objective : Class II malocclusion has been extensively studied, however there are many unanswered questions. This study analyzed the difference in incisor and molar dentoalveolar heights of untreated subjects presenting with Class I and Class II malocclusion. Dentialveolar heights are an aspect of the craniofacial complex that changes with growth and development and are manipulated by orthodontists. These changes hold important clinical implications for the development, maintenance and treatment of malocclusions. Methods : A sample of 96 untreated Class I and Class II subjects, with a total of 611 cephalograms was drawn from the archives of the University of Michigan …

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Ecumenical Traditions: Byzantine And Franciscan Theology In Dialogue, Gino G. Grivetti Jul 2023

Ecumenical Traditions: Byzantine And Franciscan Theology In Dialogue, Gino G. Grivetti

Master's Theses (2009 -)

This thesis investigates the convergences between the Byzantine and Franciscan traditions in the areas of hagiography, mysticism, and dogmatic theology. Historically marginalized in the neo-scholastic synthesis of the nineteenth century, the closeness of Patriarch Bartholomew (b. 1940) and Pope Francis (b. 1936) has symbolized the significance of this dialogue in the modern ecumenical movement. The anonymous bios of St. Nilus of Rossano (d. 1005) and the first vita of St. Francis of Assisi (d. 1226) by Thomas of Celano (d. 1260) are representative of the hagiographical traditions of the Italo-Byzantine monks and the early Franciscans. The traditions came into direct …

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Short And Long-Term Effects Of Conventional And Miniscrew-Assisted Rapid Palatal Expansion On Hard Tissues Using Voxel-Based Superimposition Of Serial Cbcts, Isaac R. Empson Jul 2023

Short And Long-Term Effects Of Conventional And Miniscrew-Assisted Rapid Palatal Expansion On Hard Tissues Using Voxel-Based Superimposition Of Serial Cbcts, Isaac R. Empson

Master's Theses (2009 -)

Objective: The objective of this study was to evaluate the short-term and long-term hard tissue changes with miniscrew-assisted rapid palatal expansion (MARPE) and rapid palatal expansion (RPE) compared to a matched control group with voxel based superimposition and three dimensional cone-beam computed tomography (CBCT) analysis. Methods:After IRB review, a total of 180 cone beam computed tomography (CBCT) scans were analyzed for 60 patients with a mean age of 13.9 years at 3 time points: pretreatment (T1), Post-Expansion (T2), and Post-treatment (T3). Patients were divided into 3 groups: MARPE, RPE, and controls. Voxel-based superimposition was performed for CBCTs from T1 to …

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Reducing Porosity In Lpbf Ti-6al-4v By Parameter Optimization And Low Temperature Hot Isostatic Pressing Cycle, Penn Rawn Jul 2023

Reducing Porosity In Lpbf Ti-6al-4v By Parameter Optimization And Low Temperature Hot Isostatic Pressing Cycle, Penn Rawn

Master's Theses (2009 -)

Powder bed based additive manufacturing has advantages in its ability to make specialized parts with complex geometries. Unfortunately, components made through such processes of suffer from manufacturing defects including porosity. To study pore formation and removal, specimens of Ti-6Al-4V were built at varied levels of laser power, travel speed, hatch spacing, and layer thickness to obtain a variety of initial defect populations. The specimens were then subjected to a hot isostatic pressure (HIP) at 850 °C and 200 MPa to evaluate the low temperature high pressure (LTHP) cycle’s ability to remove pores. Image analysis was used to estimate the relative …

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Philippine Structural Transformation - With Or Without Maharlika, Jesus Felipe, Mariel Monica R. Sauler, Gerardo L. Largoza, Lawrence B. Dacuycuy, Christopher James R. Cabuay, Jason P. Alinsunurin, Arlene B. Inocencio, Albert E. Lamberte, Natasha Amber Y. Cabiltes Jul 2023

Philippine Structural Transformation - With Or Without Maharlika, Jesus Felipe, Mariel Monica R. Sauler, Gerardo L. Largoza, Lawrence B. Dacuycuy, Christopher James R. Cabuay, Jason P. Alinsunurin, Arlene B. Inocencio, Albert E. Lamberte, Natasha Amber Y. Cabiltes

Angelo King Institute for Economic and Business Studies (AKI)

It appears the Maharlika Investment Fund (MIF) is a fait accompli. As we write, our finance officials are in New York and Toronto, pitching the MIF to international bankers and representatives of Middle East sovereign wealth funds. This means once President Marcos, Jr. affixes his signature, a newly-created Maharlika Investment Corporation (MIC) will pool, before the year is over, PhP 75 billion in seed capital from the LandBank and Development Bank of the Philippines. With a further PhP 50 billion plus two full years of dividends from the Bangko Sentral ng Pilipinas (BSP), its nine directors, all presidential appointees, will …

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The Availability Of Organizational Health Dimensions In Basic Education Schools In Al Batinah North Governorate During Distance Learning From Teachers’ Point Of View, Ali H. Al Balushi Jul 2023

The Availability Of Organizational Health Dimensions In Basic Education Schools In Al Batinah North Governorate During Distance Learning From Teachers’ Point Of View, Ali H. Al Balushi

Journal of Educational and Psychological Studies

This study aimed to identify the availability of the dimensions of organizational health in basic education schools in the perceptive of online teaching in Al Batinah North Governorate in Sultanate of Oman from the teachers’ point of view. The descriptive method was adopted in this study. A random sample consisted of 530 teachers from basic education schools in sultanate of Oman in 2020/2021 was selected. And the researcher used a survey that included four dimensions, which are school cohesion dimension, initiative dimension, support resource dimension, and morality dimension. The result of the study showed that the level of availability of …

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Compartive Study Between Iv Acetaminophen (Paracetamol) And Iv Morphine In Preventing Postoperative Pain During Laparoscopic Cholecystectomy, Ismael Waadullah Ismael, Hussam Kareem Mughames Jul 2023

Compartive Study Between Iv Acetaminophen (Paracetamol) And Iv Morphine In Preventing Postoperative Pain During Laparoscopic Cholecystectomy, Ismael Waadullah Ismael, Hussam Kareem Mughames

Al-Nisour Journal for Medical Sciences

Pain is "an uncomfortable sensory and emotional experience related to existing or potential tissue damage, or defined in terms of such damage," according to the International Association for the Study of Pain. Following a laparoscopic cholecystectomy, the patient experiences painful shoulder and abdominal pain. Peritoneal stretching and diaphragmatic irritation by increased intra-abdominal pressure brought on by pneumoperitoneum are two possible reasons of this pain. Presence of this pain may cause uses of analgesic drugs, to provide a better level of analgesia for patient undergoing laparoscopic cholecystectomy and reduce the consumption and the side effects of opioids Sixty adults males and …

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The Physiological Effects Of Remifentanil On Hemodynamic Stability During Elective Surgery, Mohammed Abdulhameed Younis Jul 2023

The Physiological Effects Of Remifentanil On Hemodynamic Stability During Elective Surgery, Mohammed Abdulhameed Younis

Al-Nisour Journal for Medical Sciences

The general anaesthesia inductions may cause hemodynamics disturbance. These responses are often suppressed by administration of remifentanil. In this study the aim is to assess the effects of infusion Remifentanil on hemodynamic stability during general anesthesia. This prospective study we collects 50 healthy patients aged between 20 to 65 years scheduled for elective surgery in Baghdad teaching hospital with ASA, (I. II). All these patients received 1mcg/kg/min remifentanil by continuous infusion over 30 minutes. The recording of mean arterial, heart rate, respiratory rate and peripheral oxygen saturation 10, 5 minutes pre induction, throughout infusion and at 5, 10, 15 Minutes …

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The Relationship Between Alkaline Phosphates Level, Liver Diseases And Gallstone, Abdulameer Jassim Mohammed, Qasim Mohammed Banjah, Walaa Abdulhussein Abbas Al-Azzawi Jul 2023

The Relationship Between Alkaline Phosphates Level, Liver Diseases And Gallstone, Abdulameer Jassim Mohammed, Qasim Mohammed Banjah, Walaa Abdulhussein Abbas Al-Azzawi

Al-Nisour Journal for Medical Sciences

Alkaline phosphatase is an enzyme produced primarily by the liver. Tests for alkaline phosphatase can be part of routine lab work or part of a series of tests called a liver panel, which includes tests for other liver enzymes, such as aspartate aminotransferase, or alanine aminotransferase. This study aims to find out the effect of alkaline phosphatase enzyme on liver diseases and gallstones. Alkaline phosphatase level was measured for fifty patients suffering from gallstone (30 patients), obstructive disease (10 patients) and liver cirrhosis (10 patients). All patients grouped according to the ages (Each five years as a group), all female …

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Monitoring Of Leptin Hormone Levels In Child Bearing – Age Women In Baghdad / Iraq – With Polycystic Ovary Syndrome, And The Impact Of Bmi On Leptin Levels, Bahaa Burhanuldeen Kargule, Farah A. Dawood Jul 2023

Monitoring Of Leptin Hormone Levels In Child Bearing – Age Women In Baghdad / Iraq – With Polycystic Ovary Syndrome, And The Impact Of Bmi On Leptin Levels, Bahaa Burhanuldeen Kargule, Farah A. Dawood

Al-Nisour Journal for Medical Sciences

At Poly-cystic ovarian syndrome (PCOS) pathway and duration, there are Hormonic elevations in Androgen and testosterone. Since PCOS is a metabolic disorder, the present study is designed to monitor Leptin levels at PCOS, being there is a common cause between metabolic disorder and PCOS. All potential biological factors that affect Leptin levels were isolated, in order to monitor exclusively BMI effect on serum Leptin levels at PCOS. The result illustrated that serum leptin level is not associated with the duration of PCOS in proportion to non-significant statistics of the present results which showed between leptin and PCOS duration, hence leptin …

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Relationship Between The Demographic Factors Of People Living In Cholera Endemic Areas And Their Knowledge Towards The Preventive Measures Against The Disease, Zainab Mohamed Mahmmod, Tabarek Ayad Noori, Ali Najm Abdullah Jul 2023

Relationship Between The Demographic Factors Of People Living In Cholera Endemic Areas And Their Knowledge Towards The Preventive Measures Against The Disease, Zainab Mohamed Mahmmod, Tabarek Ayad Noori, Ali Najm Abdullah

Al-Nisour Journal for Medical Sciences

Cholera is an infectious, acute bacterial disease caused by Vibrio Cholera. Watery diarrhea is the predominant clinical sign of the disease. Around the world, it is thought to be responsible for up to 4 million cases annually. This digestive contagious is characterized by high-volume fluid loss and electrolyte disturbances that may advance to hypovolemic shock and finally death. This survey study seeks to discover how well-informed, how individuals in Diyala, Iraq, feel about cholera epidemics, and how they behave in practice. In the present research, there were a total of 272 participants, with a mean age of 20 to 29 …

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Modelling Climate Litigation Risk For (Re)Insurers, Martin Lockman Jul 2023

Modelling Climate Litigation Risk For (Re)Insurers, Martin Lockman

Sabin Center for Climate Change Law

In response to the growing threat of climate change, the insurance industry has made significant investments in modelling and quantifying physical climate risks. However, the emerging risk of climate litigation has proven particularly difficult to model. In 2015 Mark Carney, then-Governor of the Bank of England and Chairman of the Financial Stability Board, warned that climate litigation poses “long-tail risks” for insurers that may be “significant, uncertain and non-linear.” Since that warning, the number of climate-related cases has more than doubled, and the scope and financial significance of climate litigation has become increasingly clear. However, insurers and regulators still struggle …

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Excitatory Dorsal Lateral Prefrontal Cortex Transcranial Magnetic Stimulation Increases Social Anxiety, Anthony Minervini, Adriana Lavarco, Samantha Zorns, Ruth Propper, Christos Suriano, Julian Paul Keenan Jul 2023

Excitatory Dorsal Lateral Prefrontal Cortex Transcranial Magnetic Stimulation Increases Social Anxiety, Anthony Minervini, Adriana Lavarco, Samantha Zorns, Ruth Propper, Christos Suriano, Julian Paul Keenan

Department of Psychology Faculty Scholarship and Creative Works

Social exclusion refers to the experience of rejection by one or more people during a social event and can induce pain-related sensations. Cyberball, a computer program, is one of the most common tools for analyzing social exclusion. Regions of the brain that underlie social pain include networks linked to the dorsal lateral prefrontal cortex (DLPFC). Specifically, self-directed negative socially induced exclusion is associated with changes in DLPFC activity. Direct manipulation of this area may provide a better understanding of how the DLPFC can influence the perception of social exclusion and determine a causal role of the DLPFC. Transcranial magnetic stimulation …

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Latine Youth's Intersecting Identities And Mental Health Outcomes: Examining The Mediating Role Of Family Functioning, Anne Malkoff Jul 2023

Latine Youth's Intersecting Identities And Mental Health Outcomes: Examining The Mediating Role Of Family Functioning, Anne Malkoff

Dissertations (1934 -)

In the existing literature base, the mechanisms by which a bicultural identity leads to more positive mental health outcomes among Latine youth are not yet clearly understood. The present study aimed to clarify these relationships by examining family functioning as a possible mediating variable between Latine youth’s cultural identity-related processes (i.e., bicultural identity integration, bicultural stress, ethnic identity, parent-child acculturation differences) and mental health outcomes (i.e., internalizing/externalizing symptoms and overall well-being). Participants included Latine youth (ages 9-12; n = 78) and their parents (n = 70) who were primarily recruited to participate in the study via Facebook over the course …

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Existential Thomism And The Ecstasy Of The Sexed Body, Kathleen Cavender-Mccoy Jul 2023

Existential Thomism And The Ecstasy Of The Sexed Body, Kathleen Cavender-Mccoy

Dissertations (1934 -)

This dissertation assesses the relevance and significance of Norris Clarke’s existential Thomism to critiques of John Paul II’s theology of the body. I argue that using existential Thomism as a basis for Catholic metaphysics opens the door for an existential theology of the sexed body, a theology of the individual on a unique spiritual journey towards union with God which amends, expands, and nuances the existing theology of the ecstatic body developed by John Paul II. Chapter One situates my thesis within its historical context by tracing philosophical and theological developments which inform the current status of embodied sexual difference …

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Exploring Validation And Success Among First-Generation College Students In First-Year Writing, Jenna Green Jul 2023

Exploring Validation And Success Among First-Generation College Students In First-Year Writing, Jenna Green

Dissertations (1934 -)

This qualitative case study examines connections between student writing and student success, specifically among first-generation college students, a growing student population who are less likely to graduate college than their multigenerational peers. First-generation college students are more likely to come from working-class, low-income backgrounds, identify as racial or ethnic minorities, live at home and/or have significant family and work responsibilities (Bond, 2019; Engle & Tinto, 2008). Due to the confluence of barriers many face, first-generation college students exhibit higher attrition rates, contributing to persisting inequities in higher education. Leveraging Rendón’s (1994) validation theory, this study explored how first-generation college students …

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Breathing Around The Clock: Novel Circadian And Light-Driven Mechanisms That Govern Daily Breathing Behavior In Mice, Aaron Andrew Jones Jul 2023

Breathing Around The Clock: Novel Circadian And Light-Driven Mechanisms That Govern Daily Breathing Behavior In Mice, Aaron Andrew Jones

Dissertations (1934 -)

Breathing, like many physiological functions, exhibits a daily rhythm in mammals that coincides with periods of wakefulness and increased metabolic activity. Dysregulation of daily breathing rhythms has been implicated in a variety of respiratory diseases with time-specific symptomatology including sleep apnea, asthma, chronic pulmonary disease, sudden unexpected death in epilepsy, and COVID-19. While the daily rhythm in breathing is regulated by the endogenous circadian clock in the brain, the underlying physiological and cellular mechanisms modulating daily breathing behavior remain largely unknown. Light is the most potent synchronizer of the circadian system in mammals and is likely the principal driver of …

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Generation Of Cardiac Chamber Models Using Interpretable Generative Neural Networks For Electrophysiology Studies, Sunil Mathew Jul 2023

Generation Of Cardiac Chamber Models Using Interpretable Generative Neural Networks For Electrophysiology Studies, Sunil Mathew

Dissertations (1934 -)

An Electrophysiology study is conducted to diagnose and treat heart rhythm disorders, such as arrhythmias (abnormal heartbeat) like atrial fibrillation. A catheter is inserted into the chamber of interest to acquire 3D location and electrical information to create an electroanatomical map. This dissertation explores the design of a mapping system based on interpretable generative neural networks for generating patient specific cardiac models. Chapter 1 provides an introduction to electroanatomical mapping, the need for interpretability in neural networks and other relevant topics that are discussed in detail in the chapters that follow. Neural networks are often very large models with millions …

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Photophysical And Photocatalytic Properties Of Covalent Organic Frameworks, Daniel Streater H. Jul 2023

Photophysical And Photocatalytic Properties Of Covalent Organic Frameworks, Daniel Streater H.

Dissertations (1934 -)

This dissertation is most interested in how a class of materials known as covalent organic frameworks (COFs) can be designed to capture photon energy to initiate chemical reactions. Different COF designs change how long the energy is held, how it migrates, and how it is dispersed – and these differences can be used to change their performance as artificial photosynthesis platforms. Thus, it is helpful to have an informative discussion about the processes behind natural photosynthesis, that is, nature’s light harvesting strategies and photocatalytic schemes (Section 1.2) and will lead into an introduction of COFs and why they possess unique …

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Elucidating The Structure And Regulatory Interactions Of The Hotair Non-Coding Rna And The Bacterial Rnase P. Holoenzyme, Ainur Abzhanova Jul 2023

Elucidating The Structure And Regulatory Interactions Of The Hotair Non-Coding Rna And The Bacterial Rnase P. Holoenzyme, Ainur Abzhanova

Dissertations (1934 -)

RNA structures and RNA-protein interactions are studied as potential drug targets, biomarkers in cancer, and can be administered as vaccines. The cancer associated HOTAIR (HOX transcript antisense RNA) exists in higher vertebrates and interacts with chromatin remodeling enzymes. We examined the thermodynamic folding properties and structural propensity of the exonic regions of HOTAIR using biophysical methods and NMR spectroscopy. Different exons of HOTAIR contain variable degrees of structural heterogeneity. We identify one exonic region, exon 4, that adopts a stable and compact fold under low magnesium concentrations. Close agreement of NMR spectroscopy and chemical probing confirm conserved base pair interactions …

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A Trait-Based Approach To Explain Plant Coexistence In Tropical Forests, Felipe Nery Arantes Mello Jul 2023

A Trait-Based Approach To Explain Plant Coexistence In Tropical Forests, Felipe Nery Arantes Mello

Dissertations (1934 -)

Ecology seeks to explain the mechanisms that allow multiple species to coexist in the same habitat without one species outcompeting or driving others to extinction. Niche differentiation is a mechanism that has been proposed to allow species to coexist through specialization on different resources or habitats, which reduces competition and the probability of competitive exclusion. Species can reduce competition by using different combinations of resources and thus partitioning available resources in time and space. Differences in resource use is hypothesized to be influenced by species’ morphological and physiological adaptations, known as functional traits. Links between functional traits and abiotic factors …

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Scope And Mechanistic Studies Of Ruthenium Catalyzed C-C And C-N Bond Activation Reactions, Dulanjali Thennakoon Jul 2023

Scope And Mechanistic Studies Of Ruthenium Catalyzed C-C And C-N Bond Activation Reactions, Dulanjali Thennakoon

Dissertations (1934 -)

Transition metal catalyzed selective C–C and C–N bond activation reactions emerged as an effective synthetic tool in organic chemistry. Reorganization of these bond connections allows access to complex molecular scaffolds from readily available starting materials which are immensely useful for organic synthesis of pharmaceutical agents. While enormous progress has been achieved to date, major challenges still remain in desigining broad applicable catalytic bond activation methods. The well-defined cationic Ru–H complex with a benzoquinone ligand was found to be an effective catalytic system for the deaminative coupling reaction of enones with amines which enable regioselective cleavage of unstrained Cα–Cβ bond of …

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Nepantla And Mestizaje: A Phenomenological Analysis Of The Mestizx Historical Consciousness, Jorge Alfredo Montiel Jul 2023

Nepantla And Mestizaje: A Phenomenological Analysis Of The Mestizx Historical Consciousness, Jorge Alfredo Montiel

Dissertations (1934 -)

My dissertation consists of two main Parts. Part I draws from Edmund Husserl’s notion of the “historical a priori” and from seminal decolonial thinker Anibal Quijano’s formulation of “coloniality” to offer a framework for what I call the “coloniality of history.” Chapter 1 draws from Husserl’s and from contemporary analyses of the “historical a priori” as a historical horizon of conceivability for subject and truth formation. Chapter 2 brings this phenomenological analysis to interpret Quijano’s formulation of “coloniality” as a historical horizon of conceivability and to offer a framework for what I call the “coloniality of history.” This framework shows …

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Improving Cold Tolerance Of Asian Rice Through Plant Growth Promoting Bacteria And Rice Gene Manipulation: Mechanisms Of Pseudomonas Mosselli And Osmads27, Nasim Maghboli Balasjin Jul 2023

Improving Cold Tolerance Of Asian Rice Through Plant Growth Promoting Bacteria And Rice Gene Manipulation: Mechanisms Of Pseudomonas Mosselli And Osmads27, Nasim Maghboli Balasjin

Dissertations (1934 -)

It is estimated that by the year 2050, the human population will extend to 9.7 billion and therefore the demand for food will increase. It is important to find ways to maintain production of critical crops, like rice, to match the demand. Climate change affects crop productivity as it is the reason for extreme warm or cold weather fluctuations. Asian rice (Oryza sativa L.) generally is grown in tropical and subtropical regions and thus, is sensitive to cold temperatures. This study hypothesized two strategies could improve growth and cold tolerance of rice plants: (1) use of plant growth promoting bacteria …

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Identification Of The Autoregulatory Properties And Molecular Interactions Of The Lysine-Specific Histone Demethylase 1 Enzyme, Dulmi Senanayaka Jul 2023

Identification Of The Autoregulatory Properties And Molecular Interactions Of The Lysine-Specific Histone Demethylase 1 Enzyme, Dulmi Senanayaka

Dissertations (1934 -)

The conserved chromatin-remodeling enzyme, Lysine-Specific histone1/2 Demethylase 1 (LSD1) primarily demethylates Histone H3K4me , acting as a transcriptional repressor. It plays pivotal roles in various physiological processes including cancer and interacts with many regulatory proteins, non-coding RNAs, and small metabolites. However, little biochemical information is known about LSD1’s N-terminal intrinsically disordered region (IDR) and how LSD1 interacts with various biomolecules in the context of nucleosome. I present evidence that the IDR of LSD1, containing multiple post translational modifications (PTMs) and a nuclear localization signal (NLS), can act as a reversible competitive autoinhibitor of LSD1’s activity. This autoinhibition can be relieved …

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