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Articles 369991 - 370020 of 5172482
Full-Text Articles in Entire DC Network
Genetic Or Pharmacological Ghsr Blockade Has Sexually Dimorphic Effects In Rodents On A High-Fat Diet, András H Lékó, Adriana Gregory-Flores, Renata C N Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro P Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Genetic Or Pharmacological Ghsr Blockade Has Sexually Dimorphic Effects In Rodents On A High-Fat Diet, András H Lékó, Adriana Gregory-Flores, Renata C N Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro P Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Faculty, Staff and Students Publications
The stomach-derived hormone ghrelin regulates essential physiological functions. The ghrelin receptor (GHSR) has ligand-independent actions; therefore, GHSR gene deletion may be a reasonable approach to investigate the role of this system in feeding behaviors and diet-induced obesity (DIO). Here, we investigate the effects of a long-term (12-month) high-fat (HFD) versus regular diet on obesity-related measures in global GHSR-KO and wild-type (WT) Wistar male and female rats. Our main findings are that the GHSR gene deletion protects against DIO and decreases food intake during HFD in male but not in female rats. GHSR gene deletion increases thermogenesis and brain glucose uptake …
The (Limited) Competitive Advantage Of Tax Planning, Gang Pan
The (Limited) Competitive Advantage Of Tax Planning, Gang Pan
Olin Business School Graduate Student Theses and Dissertations
This dissertation documents that corporate tax planning innovations, proxied by decreases in effective tax rates, contribute to excess shareholder returns and, thereby, a competitive advantage. Compared to other improvements in firm performance, tax planning innovations have smaller factor loadings and explain fewer variations in excess returns. Notably, sales growth explains more than seven times the variations in excess returns compared to tax planning innovations. Tax planning even falls behind interest expense reductions, given the challenge of altering firm capital structure. To address the concern that changes in firm performance drive the association between tax planning innovations and excess returns, I …
Radiotherapy Plan Quality Assurance In Nrg Oncology Trials For Brain And Head/Neck Cancers: An Ai-Enhanced Knowledge-Based Approach, Du Wang, Jeff M Michalski, Jiayi Huang, Et Al.
Radiotherapy Plan Quality Assurance In Nrg Oncology Trials For Brain And Head/Neck Cancers: An Ai-Enhanced Knowledge-Based Approach, Du Wang, Jeff M Michalski, Jiayi Huang, Et Al.
2020-Current year OA Pubs
The quality of radiation therapy (RT) treatment plans directly affects the outcomes of clinical trials. KBP solutions have been utilized in RT plan quality assurance (QA). In this study, we evaluated the quality of RT plans for brain and head/neck cancers enrolled in multi-institutional clinical trials utilizing a KBP approach. The evaluation was conducted on 203 glioblastoma (GBM) patients enrolled in NRG-BN001 and 70 nasopharyngeal carcinoma (NPC) patients enrolled in NRG-HN001. For each trial, fifty high-quality photon plans were utilized to build a KBP photon model. A KBP proton model was generated using intensity-modulated proton therapy (IMPT) plans generated on …
Clinical Nurse Manager Fatigue And Its Personal And Professional Impacts, Carlene Galanopulo
Clinical Nurse Manager Fatigue And Its Personal And Professional Impacts, Carlene Galanopulo
Walden Dissertations and Doctoral Studies
Workplace fatigue has been empirically linked with errors, injuries, and chronic health issues that negatively impact the healthcare worker, patients, and staff with whom that person comes in contact, as well as the organization for which that person works. The experience of fatigue in clinical nurse managers (CNMs) has been understudied. The purpose of this study was to understand the individual experience of fatigue and its professional and personal impacts as more fully described by CNMs. The research question that guided this study involved the professional and personal impact of fatigue as described by CNMs. The occupational fatigue in nursing …
Social Support, Caregiver Burden, And Anxiety/Depression Among Family Caregivers Of Stroke Patients, Rosalyn Moore
Social Support, Caregiver Burden, And Anxiety/Depression Among Family Caregivers Of Stroke Patients, Rosalyn Moore
Walden Dissertations and Doctoral Studies
Family caregivers encounter challenges when caring for relatives recovering from a stroke. Family caregivers often experience negative mental health outcomes including higher levels of anxiety, depression, and stress. The purpose of this study was to determine the extent to which years of caregiving experience, emotional and instrumental support, and caregiver burden predict anxiety and depression among family caregivers of stroke patients. The caregiving stress process model theoretical framework guided the research. This quantitative study used a non-experimental correlational research design. Participants were recruited using Survey Monkey and included a non-random convenience sample of 111 family caregivers of stroke patients who …
Comparison Of Vivitrol And Suboxone In Terms Of Lowering Relapse Among Opioid Addicts, Nicolle Tourdot
Comparison Of Vivitrol And Suboxone In Terms Of Lowering Relapse Among Opioid Addicts, Nicolle Tourdot
Walden Dissertations and Doctoral Studies
Drug overdoses are increasing, and the heroin epidemic is becoming more evident. There are ways to get these individuals’ help. Medically assisted treatments (MATs) involve use of medications alongside counseling and therapies to treat individuals with a substance abuse disorder. This subject is important to the human services administration field, more specifically those who focus on addiction. As the epidemic of opioid use continues, so does the need for treatment. Without that treatment, the problem will get worse and inevitably have negatives effects on the entire world. Those effects involve crime, increasing costs to the public, overall health, and child …
Lived Experiences Of Quality Of Life Among Makonde Immigrants In Kenya During And After The Covid-19 Pandemic, Shem Migosi Kenyanya
Lived Experiences Of Quality Of Life Among Makonde Immigrants In Kenya During And After The Covid-19 Pandemic, Shem Migosi Kenyanya
Walden Dissertations and Doctoral Studies
The COVID-19 pandemic affected Makonde immigrants’ health and quality of life around the world more than any other previous event. This descriptive qualitative study aimed to contribute knowledge and understanding of the lived experiences of Makonde immigrants and their health and quality of life during and after the COVID-19 pandemic. Shye’s systematic quality of life model served as the theoretical basis for the study, along with Wilson and Cleary’s conceptual model of health quality of life. Semi-structured interviews were conducted with ten participants recruited through social media and flyers posted in Kilifi and Kwale counties. Subjects were interviewed face-to-face and …
Vocabulary Retention And Color Effect Differences Among Developmental Community College Students, Eric Scott Coleman
Vocabulary Retention And Color Effect Differences Among Developmental Community College Students, Eric Scott Coleman
Walden Dissertations and Doctoral Studies
The completion of developmental community college (DCC) courses is a crucial step in community college education to reach the national goal of increasing college success. DCC students are a unique population who require specific strategies such as vocabulary retention (VR) to achieve academic success. Prior research on vocabulary has been limited to VR and color effects. However, there is a lack of research on the intersection of these two variables (VR and color effects). This quantitative research study used the theoretical lens feature integration theory (FIT) to examine the effects that text color has on VR among DCC students. Additionally, …
Challenges Faced By Information Technology Project Managers When Adopting Network Automation, Joshua Allen Kerley
Challenges Faced By Information Technology Project Managers When Adopting Network Automation, Joshua Allen Kerley
Walden Dissertations and Doctoral Studies
Automating network services is vital for small and medium-sized enterprises (SMEs) to remain viable and competitive, but implementation has challenges. Without evidence-based strategies to help IT project managers curb those challenges, the transition to automating network services could be hindered. Grounded in Lewin’s change model, the purpose of this qualitative pragmatic inquiry was to explore the methods used by IT project managers in network engineering to curb the challenges they face when automating network services. Semi-structured interviews were conducted with a purposive sample of 10 IT project managers from non-governmental SMEs in Florida, US. The data were thematically analyzed, and …
Impact Of Toxic Leadership On The Mental Health Of Employees In Texas State Agencies, Dr. Monika Diaz
Impact Of Toxic Leadership On The Mental Health Of Employees In Texas State Agencies, Dr. Monika Diaz
Walden Dissertations and Doctoral Studies
This study investigated the impact of toxic leadership on the mental health of employees within Texas state agencies, utilizing betrayal trauma theory (BTT) as the theoretical framework. The study was conducted using a qualitative approach, specifically through semi-structured interviews with eight employees who have experienced toxic leadership firsthand. These interviews aimed to uncover the psychological effects of such leadership on employees, with particular attention to symptoms of stress, anxiety, and job satisfaction. Data were analyzed through thematic analysis. The findings revealed that toxic leadership was significantly associated with increased psychological distress among employees. This distress manifested as heightened anxiety, depression, …
Military Sexual Trauma And The Psychological And Emotional Well-Being Of Gay Men, Alisha Simmons
Military Sexual Trauma And The Psychological And Emotional Well-Being Of Gay Men, Alisha Simmons
Walden Dissertations and Doctoral Studies
Researchers have found that male survivors of military sexual trauma (MST) may not report their assaults due to a combination of stigma, embarrassment, and fear of further assault and of being labeled a betrayer of the military. The stigma and discrimination that these gay males may face in the military culture may lead to intensifying their trauma, making it harder to recover. The goal of this study was to explore the reported psychological and emotional well-being and quality of life of gay males who experienced sexual assault while serving in the military. Freyd’s theory of betrayal trauma and institutional betrayal …
The Self-Perceived Level Of Wellness Among Ghanaian Mental Health Counselors, Adwoa Bonney-Graves
The Self-Perceived Level Of Wellness Among Ghanaian Mental Health Counselors, Adwoa Bonney-Graves
Walden Dissertations and Doctoral Studies
In Ghana, many people seek help for their mental health; however, despite the great need, there are often barriers or factors that can create unwellness among mental health counselors. There is a gap in the research literature addressing whether unwellness among Ghanaian mental health counselors is caused by external factors of counselor caseload, low funding, and minimal work staff. This quantitative study aimed to fill this gap by using predictive regression analysis to determine whether there is a correlation between Ghanaian counselors’ unwellness and counselor caseload, low funding, and minimal work staff. The study participants (N = 96) were Ghanaian …
Contributor Biographies, Editors Of Suurj
Contributor Biographies, Editors Of Suurj
SUURJ: Seattle University Undergraduate Research Journal
No abstract provided.
Acknowledgments, Editors Of Suurj
Acknowledgments, Editors Of Suurj
SUURJ: Seattle University Undergraduate Research Journal
No abstract provided.
The Path To Rehabilitation?: A Policy Analysis Of Juvenile Isolation And Room Confinement In Washington State, Trevor Buchan
The Path To Rehabilitation?: A Policy Analysis Of Juvenile Isolation And Room Confinement In Washington State, Trevor Buchan
SUURJ: Seattle University Undergraduate Research Journal
Throughout the United States, the practice of isolating and confining youth for hours at a time is commonplace in juvenile facilities. The use of isolation in Washington State’s juvenile system is no exception. Washington recently acknowledged the dangers of juvenile solitary confinement but continues to utilize the similar practices of isolation and room confinement today. Isolation and confinement require further examination as they can cause significant harm to a youth’s social, physical, and educational development, increase youth aggression, and increase recidivism rates. Washington should reconsider whether to permit such a damaging punishment in a system purportedly committed to the rehabilitation …
The Applications Of Edna Metabarcoding As A Tool For Conservation Biology, Aidan P. Gillespie
The Applications Of Edna Metabarcoding As A Tool For Conservation Biology, Aidan P. Gillespie
SUURJ: Seattle University Undergraduate Research Journal
Measuring ecosystem biodiversity has historically been challenging, invasive, and timeconsuming. Recent advances in molecular biology technologies and techniques over the past two decades have enabled the use of environmental DNA (eDNA) as a tool for studying biodiversity. Environmental DNA refers to the DNA from all organisms in an ecosystem that enter the environment through various pathways. Since the development of high-throughput DNA sequencing (HTS) techniques, researchers have adopted eDNA metabarcoding as a noninvasive, inexpensive, and technically simple method for describing ecosystem biodiversity. The present review will describe current eDNA metabarcoding techniques and technical considerations, and then provide a selection of …
Environmental Land-Use Changes Since The 2016 Colombian Peace Accord, Gabriela Batinich
Environmental Land-Use Changes Since The 2016 Colombian Peace Accord, Gabriela Batinich
SUURJ: Seattle University Undergraduate Research Journal
The 2016 Colombian Peace Accord sought to end over fifty years of internal armed conflict and begin the process of peacebuilding nationwide. The Peace Accord outlines strategies to rebuild an effective government, amongst other plans, yet no notable environmental policies were included in the Peace Accord. Post-conflict transitional periods and their relationships to the environment are nuanced and complex issues. This paper reviews empirical studies of landuse/ land-cover change and environmental degradation in the post-Peace Accord period (2016 onward) to assess how the Peace Accord has influenced land use at micro and macro scales across the country. The review of …
Radical Intersections: The Lives And Works Of Claudia Jones And Lorraine Hansberry, Brigid Conroy
Radical Intersections: The Lives And Works Of Claudia Jones And Lorraine Hansberry, Brigid Conroy
SUURJ: Seattle University Undergraduate Research Journal
In the mid-twentieth century, Claudia Jones and Lorraine Hansberry engaged in a multiplicity of creative works to cultivate a powerful movement of third-world communism that prioritized the abolition of oppressive systems targeting Black working women globally. Though only briefly crossing paths, the two revolutionary figures devoted their lives to the same struggle against the US imperial state. Drawing from past intellectual giants such as Karl Marx, Marcus Garvey, and Sojourner Truth, Jones and Hansberry developed transformative radical feminist theory and laid the foundation for contemporary manifestations of feminism. Their analyses of the indissoluble relation between institutional racism and the global …
Introductory Needs Assessment Of Latino Msm With Hiv Or Aids In Washington: Exploring Needs, Barriers To Care, And Wellbeing, Cullin Egge
SUURJ: Seattle University Undergraduate Research Journal
Although substantial progress has been made in the fight against the HIV and AIDS epidemic in the US, health disparities and gaps in the federal response persist, particularly for African Americans and Latinos. While men who have sex with men (MSM) continue to be the most affected population, subpopulations like Latino MSM and undocumented, foreign-born, and recent immigrant Latino MSM are disproportionately impacted by HIV-related issues. The present study offers an introductory needs assessment of 23 Latino MSM with HIV or AIDS who reside in Washington state. This research aims to analyze the HIV-related needs and experiences of this population …
Can The Results Be Trusted? Assessing The Reliability Of In-Home Drug Tests For The Detection Of Thc In Urine, Éabha R. Finn, Jennifer Huffman, Madison Calvert, Kristen Skogerboe
Can The Results Be Trusted? Assessing The Reliability Of In-Home Drug Tests For The Detection Of Thc In Urine, Éabha R. Finn, Jennifer Huffman, Madison Calvert, Kristen Skogerboe
SUURJ: Seattle University Undergraduate Research Journal
Drug testing, a crucial tool in clinical, occupational, parental, and forensic settings, aims to detect and deter illicit substance use. The accuracy of a urine drug test is determined by both sensitivity, the ability to correctly identify true positives, and specificity, the ability to correctly identify true negatives. This study assesses the accuracy of five different lateral flow immunoassay (LFI) testing devices for marijuana usage on 22 anonymous urine samples (12 positives and 10 negatives) as performed by students in Seattle University’s forensic science laboratory. Students on site interpreted the results of their tests, and photographs of the tests were …
Full-Length Research Articles: Introduction, Editors Of Suurj
Full-Length Research Articles: Introduction, Editors Of Suurj
SUURJ: Seattle University Undergraduate Research Journal
No abstract provided.
Left For Dead: The Necropolitical Landscape Of Climate Induced Migration, Kit P. G. Nosacka
Left For Dead: The Necropolitical Landscape Of Climate Induced Migration, Kit P. G. Nosacka
SUURJ: Seattle University Undergraduate Research Journal
Climate destruction is projected to occur sooner than we would like to entertain. As people operating in a late-stage capitalist world, we are preoccupied with material concerns such as income and consumerism. Without proper recognition of the future that is soon upon us, we remain complicit in the neglect of millions of lives threatened by climate collapse. Climate induced migration will displace at least half as many people as the population of the United States. About 200 million people will experience displacement from their homes and families (Myers 168). These 200 million people will be disproportionately people of color located …
Short Communications: Introduction, Editors Of Suurj
Short Communications: Introduction, Editors Of Suurj
SUURJ: Seattle University Undergraduate Research Journal
No abstract provided.
Effectiveness Of Natural Defenses Against Coastal Hazards, Savannah Hyndman
Effectiveness Of Natural Defenses Against Coastal Hazards, Savannah Hyndman
SUURJ: Seattle University Undergraduate Research Journal
Coastal hazards, such as erosion and flooding, are a danger to people and property. The typical defense against coastal hazards has been grey infrastructure, which can lower biodiversity and erode the shoreline further by preventing natural sand replenishment. Natural defenses (e.g., habitat restoration, living shorelines) have been suggested as a means to address shoreline erosion and flooding. It is uncertain, however, if natural defenses are effective at combating coastal hazards. This review analyzes existing literature on natural defenses to assess whether they can provide an effective and ecologically sound means for coastal hazard management, with an emphasis on California coastal …
The Horror Of The Menstrual Monster: Examining The Societal Implications Of Menstrual Stigma Through Horror Films, Chloe R. Platt
The Horror Of The Menstrual Monster: Examining The Societal Implications Of Menstrual Stigma Through Horror Films, Chloe R. Platt
SUURJ: Seattle University Undergraduate Research Journal
Menstrual stigma, a pervasive societal issue, is consistently depicted and reinforced within the horror film genre. Through the dissection of films such as Carrie, Ginger Snaps, Audrey Rose, and It, alongside an examination of cinematic narratives, character development, and symbolism in horror films—this paper undertakes a thorough exploration of the intersection between gender, menstruation, and the horror genre to expose the broader implications of such portrayals in both the realms of horror films and society at large. The underlying mechanism enacted to perpetuate harmful biases towards women’s menstruating bodies is the correlative depiction between menstruation and the emergence of malevolent …
Cura Personalis: A Moral Obligation For Contemporary Secular Medicine To Collaborate With Latine And Indigenous Healthcare Wisdom Sources, Azul Davila Carrasco
Cura Personalis: A Moral Obligation For Contemporary Secular Medicine To Collaborate With Latine And Indigenous Healthcare Wisdom Sources, Azul Davila Carrasco
SUURJ: Seattle University Undergraduate Research Journal
This research addresses the ethical need for collaboration between conventional medicine, sometimes referred to as contemporary secular medicine, and Latine complementary and alternative medicine (CAM). It emphasizes the significance of acknowledging Indigenous medical perspectives as a matter of justice for marginalized communities. This work seeks to both argue for ethical duties of conventional medicine and offer potential solutions for bridging the gap between conventional medicine and Latine CAM, emphasizing the historical roots of the divide and its contemporary implications. The research points towards the crucial role of collaboration to enhance healthcare and address disparities within Latine communities. The study draws …
Welcome To Suurj, Editors Of Suurj
Welcome To Suurj, Editors Of Suurj
SUURJ: Seattle University Undergraduate Research Journal
No abstract provided.
Core And University Honors Writing: Introduction, Editors Of Suurj
Core And University Honors Writing: Introduction, Editors Of Suurj
SUURJ: Seattle University Undergraduate Research Journal
No abstract provided.
Journal Masthead, Editors Of Suurj
Journal Masthead, Editors Of Suurj
SUURJ: Seattle University Undergraduate Research Journal
No abstract provided.
Table Of Contents, Editors Of Suurj
Table Of Contents, Editors Of Suurj
SUURJ: Seattle University Undergraduate Research Journal
No abstract provided.