Digital Commons Network^™

Transformation From E-Voting To E-Cheque, Yun Xing Kho, Swee Huay Heng, Syh Yuan Tan, Ji Jian Chin

School of Engineering, Computing and Mathematics

Although e-voting scheme and e-cheque scheme are two different applications, they have similarities in the scheme definitions and security properties. This inspires us to establish a relationship between the two schemes by formalising a generic transformation from e-voting to e-cheque scheme. Firstly, we define the scheme definitions and security models for both e-voting scheme and e-cheque scheme. Subsequently, we demonstrate a generic transformation framework from e-voting to e-cheque with asymptotic complexity of O n and design a formal proof to show that a secure e-voting scheme can be transformed into a secure echeque scheme. As a proof of concept, we …

Knowledge, Attitudes And Practices Of Psychiatrists In India Regarding Sudden Unexpected Death In Epilepsy (Sudep) And Seizure-Related Harm, Surobhi Chatterjee, Shivangini Singh, Sujita Kumar Kar, Rohit Shankar

Peninsula Medical School

BackgroundSudden unexpected death in Epilepsy (SUDEP) is one of the leading causes of death in people with epilepsy (PWE). Awareness and taking adequate preventive measures are pivotal to reducing SUDEP. Nearly 80% of PWE live in lower-middle-income countries (LMICs) such as India where for many, epilepsy management is by psychiatrists.AimTo evaluates the knowledge, attitude and practices of Indian psychiatrists on SUDEP and seizure risk.MethodsA cross-sectional online survey of 12 Likert response questions using validated themes, was circulated among Indian Psychiatric Society members. Non-discriminatory exponential snowballing technique leading to convenience non-probability sampling was used. The inquiry involved SUDEP-related topics including the …

Changes In Plasma Concentrations Of Per- And Polyfluoroalkyl Substances After Bariatric Surgery In Adolescents From The Teen-Longitudinal Assessment Of Bariatric Surgery (Teen-Labs) Study, Zhenjiang Li, Nikos Stratakis, Douglas I Walker, Yinqi Zhao, Fabian Christoph Fischer, Scott Bartell, Damaskini Valvi, Xiangping Lin, Zoe Coates Fuentes, Thomas Inge, Justin Ryder, Todd Jenkins, Rohit Kohli, Stephanie Sisley, Stavra Xanthakos, Sarah Rock, Michele A La Merrill, Rob Mcconnell, David V Conti, Lida Chatzi

Faculty, Staff and Students Publications

Exposure to per- and poly-fluoroalkyl substances (PFAS) is ubiquitous due to their persistence in the environment and in humans. Extreme weight loss has been shown to influence concentrations of circulating persistent organic pollutants (POPs). Using data from the multi-center perspective Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) cohort, we investigated changes in plasma-PFAS in adolescents after bariatric surgery. Adolescents (Mean age = 17.1 years, SD = 1.5 years) undergoing bariatric surgery were enrolled in the Teen-LABS study. Plasma-PFAS were measured at the time of surgery and then 6-, 12-, and 36 months post-surgery. Linear mixed effect models were used to evaluate …

Rejection Resistant Cd30car-Modified Epstein-Barr Virus-Specific T Cells As An Off-The-Shelf Platform For Cd30+ Lymphoma, Nazila Nouraee, Audrey Ma, Yezan F Hadidi, Sandhya Sharma, Cliona M Rooney

Faculty, Staff and Students Publications

Off-the-shelf (OTS) adoptive T cell therapies have many benefits such as immediate availability, improved access and reduced cost, but face the major challenges of graft-vs-host disease (GVHD) and graft rejection, mediated by alloreactive T cells present in the graft and host, respectively. We have developed a platform for OTS T cell therapies by using Epstein-Bar virus (EBV)-specific T cells (EBVSTs) expressing a chimeric antigen receptor (CAR) targeting CD30. Allogeneic EBVSTs have not caused GVHD in several clinical trials, while the CD30.CAR, that is effective for the treatment of lymphoma, can also target alloreactive T cells that upregulate CD30 on activation. …

Integration Of Ζ-Deficient Cars Into The Cd3Ζ Gene Conveys Potent Cytotoxicity In T And Nk Cells, Weijie Du, Viktor Glaser, Carla Fuster-Garcia, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-El-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios L Wagner

Faculty, Staff and Students Publications

Chimeric antigen receptor (CAR)-redirected immune cells hold significant therapeutic potential for oncology, autoimmune diseases, transplant medicine, and infections. All approved CAR-T therapies rely on personalized manufacturing using undirected viral gene transfer, which results in nonphysiological regulation of CAR-signaling and limits their accessibility due to logistical challenges, high costs and biosafety requirements. Random gene transfer modalities pose a risk of malignant transformation by insertional mutagenesis. Here, we propose a novel approach utilizing CRISPR-Cas gene editing to redirect T cells and natural killer (NK) cells with CARs. By transferring shorter, truncated CAR-transgenes lacking a main activation domain into the human CD3ζ (CD247) …

Metabolic Flux Regulates Growth Transitions And Antibiotic Tolerance In Uropathogenic Escherichia Coli, Eric C Dibiasio, Mads Hansen, Karen A Krogfelt, David C Rowley, Paul S Cohen, Jodi L Camberg

Faculty, Staff and Students Publications

Reducing growth and limiting metabolism are strategies that allow bacteria to survive exposure to environmental stress and antibiotics. During infection, uropathogenic Escherichia coli (UPEC) may enter a quiescent state that enables them to reemerge after the completion of successful antibiotic treatment. Many clinical isolates, including the well-characterized UPEC strain CFT073, also enter a metabolite-dependent, quiescent state in vitro that is reversible with cues, including peptidoglycan-derived peptides and amino acids. Here, we show that quiescent UPEC is antibiotic tolerant and demonstrate that metabolic flux in the tricarboxylic acid (TCA) cycle regulates the UPEC quiescent state via succinyl-CoA. We also demonstrate that …

Advanced Hiv Disease And Associated Factors Among Young People Aged 15-24 Years At A Tertiary Hospital In Sierra Leone: A Cross-Sectional Study, Mamadu Baldeh, Samuel Kizito, Sulaiman Lakoh, Daniel Sesay, Samuel Adeyemi Williams, Umu Barrie, Frida Dennis, Dimbintsoa Rakotomalala Robinson, Franck Lamontagne, Franck Amahowe, Patrick Turay, Ozge Sensoy Bahar, Elvin Geng, Fred M Ssewamala

2020-Current year OA Pubs

BACKGROUND: Advanced HIV disease (AHD) in young people living with HIV (PLHIV) is an increasingly pressing public health issue in sub-Saharan Africa. Despite global progress in early HIV testing and reducing HIV-related deaths, many youths experience increased rates of HIV disease progression in sub-Saharan Africa. This study describes the burden, clinical manifestations, and factors for disease progression among young PLHIV aged 15 - 24 years seeking medical services at a major public hospital in Sierra Leone.

METHODS: We performed a cross-sectional analysis of routinely collected data for PLHIV patients aged 15 to 24 seen at Connaught Hospital in Sierra Leone …

Supplementary Files For "Using Digitized Building And Weather Records To Improve The Accuracy Of Ground To Roof Snow Load Ratio Estimations", Gideon Parry, Brennan Bean

Browse all Datasets

Reliability targeted snow loads (RTLs) measure the weight in accumulated snow (i.e. snow load) that a roof is required to support to ensure the probability of failure is suf- ficiently low. This calculation has historically relied upon a probability distribution that characterizes the ratio between the annual maximum ground snow load to the annual max- imum roof snow load, a quantity referred to as Gr. The best available data for estimating Gr comes from Canadian case studies from the 1950s and 1960s. However, much of the data was never digitized, with only approximations of data being made available in scanned …

Effective Strategies For Bank Technology Leaders To Improve Soft Skills Among Information Technology Professionals, Muhammad Imran

Walden Dissertations and Doctoral Studies

Employees’ insufficient soft skills have the potential to lead to collaboration and organizational inefficiency. Business leaders are concerned with the critical issue of insufficient soft skills among information technology (IT) professionals because these skills are essential for the effective functioning of teams and overall organizational success. Grounded in Knowles’s adult learning theory, the purpose of this qualitative pragmatic inquiry was to explore strategies bank technology leaders use to enhance soft skills among IT professionals. The participants were six bank technology leaders in the banking industry who successfully implemented strategies to enhance IT professionals’ soft skills. Data were collected using semistructured …

Effective Strategies Residential Property Managers Use To Reduce Workplace Burnout And Increase Workforce Retention, Gloria Gomez Flores

Walden Dissertations and Doctoral Studies

Some residential property managers have inadequate strategies to reduce workplace burnout and increase workforce retention. Consequences of workplace burnout may include high levels of absenteeism or turnover, diminished or low job performance and productivity along with depersonalization or cynicism of the work or task itself. Grounded in the job demands-resources theory, the purpose of this qualitative pragmatic inquiry was to identify and explore strategies residential property managers in West Texas use to reduce workplace burnout and increase employee retention. The participants were seven residential property managers who had over 60 years of combined experience in residential property management. Data were …

Examining Psychosocial Stressors Among African American Women With Postpartum Depression, Audrey Rose Morris

Walden Dissertations and Doctoral Studies

Psychosocial stressors are among the causative factors of postpartum depression (PPD) in African American women. This study was a qualitative meta-analysis examining the psychosocial stressors that contribute to PPD among African American women. The aim was to identify the psychosocial stressors among African American women with PPD by examining existing literature and identifying common themes. The integrative model (IM) by Fishbein and Yzer assisted in understanding the significance of psychosocial stressors in African American women with PPD. Thematic analysis was used to generate new, more substantive meanings than those taken from individual investigations. Ten research studies were selected and examined …

Effective Strategies For Bank Technology Leaders To Improve Soft Skills Among Information Technology Professionals, Muhammad Imran

Walden Dissertations and Doctoral Studies

Employees’ insufficient soft skills have the potential to lead to collaboration and organizational inefficiency. Business leaders are concerned with the critical issue of insufficient soft skills among information technology (IT) professionals because these skills are essential for the effective functioning of teams and overall organizational success. Grounded in Knowles’s adult learning theory, the purpose of this qualitative pragmatic inquiry was to explore strategies bank technology leaders use to enhance soft skills among IT professionals. The participants were six bank technology leaders in the banking industry who successfully implemented strategies to enhance IT professionals’ soft skills. Data were collected using semistructured …

Effective Strategies Residential Property Managers Use To Reduce Workplace Burnout And Increase Workforce Retention, Gloria Gomez Flores

Walden Dissertations and Doctoral Studies

Some residential property managers have inadequate strategies to reduce workplace burnout and increase workforce retention. Consequences of workplace burnout may include high levels of absenteeism or turnover, diminished or low job performance and productivity along with depersonalization or cynicism of the work or task itself. Grounded in the job demands-resources theory, the purpose of this qualitative pragmatic inquiry was to identify and explore strategies residential property managers in West Texas use to reduce workplace burnout and increase employee retention. The participants were seven residential property managers who had over 60 years of combined experience in residential property management. Data were …

Motivation Matters: Understanding The Antidepressant Mechanism Of Physical Activity Among Young Adults, Jessica E. H. Ryan, Travis R. Menuz, Megan E. Ames

International Journal of Exercise Science

International Journal of Exercise Science 17(5): 861-873, 2024. A negative association between physical activity and depressive symptoms is consistently reported within scientific literature and physical self-concept has been suggested to mediate this pathway. However, for whom these associations are strongest remains poorly understood, and little is known about how other psychosocial factors might be implicated. Consequently, we examined how various exercise motivations, specifically appearance, physical health, and mental health, might moderate the indirect effect of physical activity on depressive symptoms through physical self-concept. Canadian young adults (N = 496, Mage = 20.36, SD = 1.87) completed an online questionnaire. …

Stepping Into The Light: Defining Culprit Lesion In Non-St Elevation Myocardial Infarction, Aditya Doni Pradana M.D., M.Sc, Arditya Damarkusuma M.D., M.Med (Clin Epi), Fiha, Hariadi Hariawan M.D., Fiha, Finasim, Dr., Fica, Fascc, Fapsic, Fscai

Journal of the Saudi Heart Association

Identifying the infarct-related artery (IRA) in a non-ST-segment-elevation acute myocardial infarction (NSTEMI) can be very challenging, particularly in a hospital that cannot perform intracoronary imaging due to certain limitations. This is because, by angiography, most patients present with multivessel coronary artery disease (CAD), diffuse disease, or non-significant CAD. We present a case of a 60-year-old female patient presented with substernal chest pain and palpitations of 6 hours duration. The first hospital contacts 12-lead electrocardiogram (ECG) showed ventricular tachycardia (VT) with unstable hemodynamics, after stabilization patient was transported to the catheterization laboratory for immediate percutaneous coronary intervention (PCI). With a clue …

Incidence, Risk Factors And Outcomes Of Acute Kidney Injury In Neonates Undergoing Open-Heart Surgeries: Single Center Experience, Faisal A. Alghamdi, Mohammed A. Bin Mahfooz, Hatim F. Almutairi, Nasser S. Alshaiban, Khaled E. Alotibi, Omar M. Kabbani, Mohamed S. Kabbani

Journal of the Saudi Heart Association

Background: Incidence and outcomes of acute kidney injury (AKI) among neonates who underwent open-heart surgery are not well highlighted in the literature. We aim to assess the incidence, risk factors, and outcome of AKI among neonates undergoing open-heart surgery. Methods: This is a retrospective cohort study between 2016 and 2021 for all neonates requiring open heart surgery. The cases were divided into 2 groups: the AKI (index) group and the non-AKI (control) group. The two groups were statistically compared for risk factors, needs for dialysis, and outcomes. Results: 100 patients fulfilled the inclusion criteria. Among them, 74 (74%) developed AKI, …

Around The Center, 1998 January/February, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on the demolition of the old School of Nursing building.

Around The Center, 1998 March, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on integrative medical practices.

Around The Center, 1998 April, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on the Pediatrics Development Center.

Around The Center, 1998 May, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature for Nurses' Week.

Around The Center, 1998 June, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on the Wellington Center for Women.

Around The Center, 1998 July, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on the new equipment at the Radiology MR Institute.

Around The Center, 1998 August/September, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on art therapy.

Around The Center, 1998 November/December, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on a disaster drill.

Assessing Smart Nation Singapore As An International Model For Ai Responsibility, Philip L. Frana

International Journal on Responsibility

While AI and other smart technologies greatly contribute to material aspects of well-being, there are concerns that they threaten quality of life in Singapore. Smart technologies and digital governance have freed up labor for activities where human empathy and understanding are unique and indispensable, but also threaten to undermine human dignity and accountability. This paper undertakes a comprehensive assessment of Singapore as an international model for AI responsibility from the perspective of the history and philosophy of technological governance. It examines the evolution of regulatory frameworks, ethical considerations, and key legal documents and social initiatives shaping the nation’s approach to …

Around The Center, 1997 January/February, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on renovations to the ICU.

Around The Center, 1997 March/April, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on a new strategic plan.

Around The Center, 1997 May, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on the new Veeck Family Center for Emergency Medicine.

Around The Center, 1997 June, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on the Creticos Cancer Center.

Around The Center, 1997 July, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on the new Lakeview Family Physicians center for primary care.