Digital Commons Network^™

Jovian Vortex Hunter: A Citizen Science Project To Study Jupiter’S Vortices, Ramanakumar Sankar, Shawn R. Brueshaber, Lucy Fortson, Candice Hansen-Koharcheck, Chris Lintott, Kameswara Mantha, Cooper Nesmith, Glenn S. Orton

Michigan Tech Publications

The Jovian atmosphere contains a wide diversity of vortices, which have a large range of sizes, colors, and forms in different dynamical regimes. The formation processes for these vortices are poorly understood, and aside from a few known, long-lived ovals, such as the Great Red Spot and Oval BA, vortex stability and their temporal evolution are currently largely unknown. In this study, we use JunoCam data and a citizen science project on Zooniverse to derive a catalog of vortices, some with repeated observations, from 2018 May to 2021 September, and we analyze their associated properties, such as size, location, and …

Diagnostic Error In Mental Health: A Review, Traber D Giardina, Hardeep Singh

Faculty, Staff and Students Publications

Diagnostic errors are associated with patient harm and suboptimal outcomes. Despite national scientific efforts to advance definition, measurement and interventions for diagnostic error, diagnosis in mental health is not well represented in this ongoing work. We aimed to summarise the current state of research on diagnostic errors in mental health and identify opportunities to align future research with the emerging science of diagnostic safety. We review conceptual considerations for defining and measuring diagnostic error, the application of these concepts to mental health settings, and the methods and subject matter focus of recent studies of diagnostic error in mental health. We …

Frequent Chd1 Deletions In Prostate Cancers Of African American Men Is Associated With Rapid Disease Progression, Pranshu Sahgal, Jia Zhou, Zsofia Sztupinszki, Denise Young, Darryl Nousome, Claire Kuo, Jiji Jiang, Yongmei Chen, Reinhard Ebner, Isabell A Sesterhenn, Joel T Moncur, Gregory T Chesnut, Gyorgy Petrovics, Gregory T Klus, Gabor Valcz, Pier Vitale Nuzzo, Dezso Ribli, Judit Börcsök, Aurel Prosz, Marcin Krzystanek, Thomas Ried, David Szuts, Kinza Rizwan, Salma Kaochar, Shailja Pathania, Alan D D'Andrea, Istvan Csabai, Shiv Srivastava, Matthew L Freedman, Albert Dobi, Sandor Spisak, Zoltan Szallasi

Faculty, Staff and Students Publications

We analyzed genomic data from the prostate cancer of African- and European American men to identify differences contributing to racial disparity of outcome. We also performed FISH-based studies of Chromodomain helicase DNA-binding protein 1 (CHD1) loss on prostate cancer tissue microarrays. We created CHD1-deficient prostate cancer cell lines for genomic, drug sensitivity and functional homologous recombination (HR) activity analysis. Subclonal deletion of CHD1 was nearly three times as frequent in prostate tumors of African American than in European American men and it associates with rapid disease progression. CHD1 deletion was not associated with HR deficiency associated mutational signatures or HR …

Zero Shot Health Trajectory Prediction Using Transformer, Jaroslaw Was, Quanzheng Li, David W Bates, Arkadiusz Sitek

Faculty, Staff and Students Publications

Integrating modern machine learning and clinical decision-making has great promise for mitigating healthcare's increasing cost and complexity. We introduce the Enhanced Transformer for Health Outcome Simulation (ETHOS), a novel application of the transformer deep-learning architecture for analyzing high-dimensional, heterogeneous, and episodic health data. ETHOS is trained using Patient Health Timelines (PHTs)-detailed, tokenized records of health events-to predict future health trajectories, leveraging a zero-shot learning approach. ETHOS represents a significant advancement in foundation model development for healthcare analytics, eliminating the need for labeled data and model fine-tuning. Its ability to simulate various treatment pathways and consider patient-specific factors positions ETHOS as …

Exploring The Complexity Of Systemic Sclerosis Etiology By Trio Whole Genome Sequencing, Elizabeth G Atkinson, Lindsay Burrage, Kim C Worley, Brian Christopher, Marka A Lyons, Shervin Assassi, Maureen D Mayes, Brendan Lee

Faculty, Staff and Students Publications

Systemic sclerosis (SSc) is a heterogeneous rare autoimmune fibrosing disorder affecting connective tissue. The etiology of systemic sclerosis is largely unknown and many genes have been suggested as susceptibility loci of modest impact by genome-wide association study (GWAS). Multiple factors can contribute to the pathological process of the disease, which makes it more difficult to identify possible disease-causing genetic alterations. In this study, we have applied whole genome sequencing (WGS) in 101 indexed family trios, supplemented with transcriptome sequencing on cultured fibroblast cells of four patients and five family controls where available. Single nucleotide variants (SNVs) and copy number variants …

Target Heart Rate Formulas For Exercise Stress Testing: What Is The Evidence?, Yochai Birnbaum

Faculty, Staff and Students Publications

Exercise stress testing (EST) is commonly used to evaluate chest pain, with some labs using 85% of age-predicted maximum heart rate (APMHR) as an endpoint for EST. The APMHR is often calculated using the formula 220-age. However, the accuracy of this formula and 85% APMHR as an endpoint may be questioned. Moreover, failing to reach 85% APMHR (known as chronotropic insufficiency) may also indicate poor cardiovascular prognosis, but measurements, such as percentage heart rate reserve (%HRR), maximum rate pressure product (MRPP), and the maximum metabolic equivalent of tasks (METs) reached during EST may provide better prediction of cardiovascular outcomes than …

Sequence-To-Expression Approach To Identify Etiological Non-Coding Dna Variations In P53 And Cmyc-Driven Diseases

Faculty, Staff and Student Publications

Disease risk prediction based on genomic sequence and transcriptional profile can improve disease screening and prevention. Despite identifying many disease-associated DNA variants, distinguishing deleterious non-coding DNA variations remains poor for most common diseases. In this study, we designed in vitro experiments to uncover the significance of occupancy and competitive binding between P53 and cMYC on common target genes. Analyzing publicly available ChIP-seq data for P53 and cMYC in embryonic stem cells showed that ~344-366 regions are co-occupied, and on average, two cis-overlapping motifs (CisOMs) per region were identified, suggesting that co-occupancy is evolutionarily conserved. Using U2OS and Raji cells untreated …

Structural Changes Likely Cause Chemical Differences Between Empty And Full Aav Capsids, Caryn Heldt, Molly A. Skinner, Ganesh S. Anand

Michigan Tech Publications

Due to the success of adeno associated viruses (AAVs) in treating single-gene diseases, improved manufacturing technology is now needed to meet their demand. The largest challenge is creating a process to separate empty and full capsids. Patients received larger capsid doses than necessary due to the presence of empty capsids. By enabling the better separation of empty and full capsids, patients would receive the greatest therapeutic benefit with the least amount of virus capsids, thus limiting potential side effects from empty capsids. The two most common empty/full separation methods used in downstream processing are ultracentrifugation and anion exchange chromatography. Both …

Guest Artist Masterclass - Stephanie Blythe, Mezzo-Soprano

Bailey School of Music Concert Programs

Guest Artist Masterclass - Stephanie Blythe, Mezzo-Soprano

Guest Artist Masterclass - Ryan Mccullough, Piano

Bailey School of Music Concert Programs

Guest Artist Masterclass - Ryan McCullough, Piano

Request For Change (Rfc-Rmap-2024-002), Mike Mcanulty, Eric Hassler

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

The Abfm Core Outcomes: The Next Step To Outcome-Based, Time-Variable Training In Family Medicine., Bryce A Ringwald

Medical Education Articles

No abstract provided.

Nurturing Well-Being In Dentistry: A Mindshed Approach, Tej Morjaria, Morag Powell

Peninsula Dental School

No abstract provided.

Dental Therapy Foundation Training: A Dental Therapist's View, Molly Langford, Morag Powell

Peninsula Dental School

No abstract provided.

Version 1 Noaa-20/Omps Nadir Mapper Total Column So2 Product: Continuation Of Nasa Long-Term Global Data Record, Can Li, Nickolay A. Krotkov, Joanna Joiner, Vitali Fioletov, Chris Mclinden, Debora Griffin, Peter J.T. Leonard, Simon Carn, Colin Seftor, Alexander Vasilkov

Michigan Tech Publications

For nearly 2 decades, the Ozone Monitoring Instrument (OMI) aboard the NASA Aura spacecraft (launched in 2004) and the Ozone Mapping and Profiler Suite (OMPS) aboard the NASA/NOAA Suomi National Polar-orbiting Partnership (SNPP) satellite (launched in 2011) have been providing global monitoring of SO2 column densities from both anthropogenic and volcanic activities. Here, we describe the version-1 NOAA-20 (N20)/OMPS SO2 product (10.5067/OMPS/OMPS_N20_NMSO2_PCA_L2_Step1.1, Li et al., 2023), aimed at extending the long-term climate data record. To achieve this goal, we apply a principal component analysis (PCA) retrieval technique, also used for the OMI and SNPP/OMPS SO2 products, to N20/OMPS. For volcanic …

Craig, Ayotte Neck-And-Neck In Nh Governor Race; Dems Hold Advantage In Races For Congress 9/19/2024, Unh Survey Center

All UNH Survey Center Polls

Joyce Craig and Kelly Ayotte are tied in the race to replace outgoing Governor Chris Sununu in New Hampshire. Democrat Maggie Goodlander leads Republican Lily Tang Williams in New Hampshire's Second Congressional District while incumbent Democrat Chris Pappas leads Republican Russell Prescott in the First Congressional District. Likely voters are generally unfamiliar with and don't understand the proposed constitutional amendment on the ballot in November raising the required judicial retirement age in the state, and very few plan at the moment to vote in favor of it.

Warren Comfortably Ahead In Ma Senate Re-Election Bid; Voters Generally Positive On Ballot Questions 9/19/2024, Unh Survey Center

All UNH Survey Center Polls

Incumbent Senator Elizabeth Warren holds a comfortable lead over Republican nominee John Deaton in the race for U.S. Senate in Massachusetts. Warren is only somewhat popular in Massachusetts while large numbers are unfamiliar with Deaton. Concerning ballot questions in the upcoming election, likely voters are largely supportive of Questions 1, 3, 4, and 5, while voters are divided on Question 2. However many voters have not heard much about these questions or are undecided.

Whitehouse Leads Morgan In Ri Senate Race; Voters Divided On Constitutional Convention Question 9/19/2024, Unh Survey Center

All UNH Survey Center Polls

Sheldon Whitehouse leads Republican nominee Patricia Morgan by double-digits in the race for U.S. Senate in Rhode Island. Three-quarters of likely voters have definitely decided who they will support in this race. Whitehouse and Morgan have similar net favorability ratings but Morgan is not nearly as well-known. Despite appearing on the ballot every ten years in Rhode Island, many likely voters have not heard about and do not understand a ballot question this year asking if the state should hold a constitutional convention to propose amendments. When asked how they will vote on this issue, residents are divided with many …

The Role Of America’S European Allies In The Russia-Ukraine War, 2022–24, John R. Deni, Lisa A. Aronsson

Books, Monographs & Collaborative Studies

©2024 John R. Deni

What more can US allies in Europe do to assist Ukraine militarily? More broadly, what can the United States expect from its closest allies in Europe in strategic competition with Russia and China? In this monograph, John R. Deni and Lisa A. Aronsson assess whether US allies and partners in Europe can continue providing military assistance to Ukraine or expand assistance, while preserving their own national security and fulfilling their NATO commitments. They also explore what the Russia-Ukraine War reveals about the role of European allies in future iterations of strategic competition. Their findings indicate European …

2024 State Of The University Address, Aondover Tarhule

State of the University Addresses

Annual address delivered by the president of Illinois State University discussing the university's accomplishments and plans for the future.

Relationship Among Parenting Styles And Latino Adolescent Self-Esteem And Aggression, Jocelyn Evans-Shaw

Doctoral Dissertations and Projects

There is considerable evidence that parenting influences the development and growth of children. Research on the psychological effects of parenting styles on children has traditionally neglected some cultures, such as the Latino community. The proposed study explored Latino parenting (authoritarian, authoritative, and permissive) styles and how they affect children's wellbeing. This quantitative study used correlational analysis to examine the relationships among aggression, self-esteem, and parenting styles among Hispanic adolescents. The study sample consisted of 77 participants. Snowball sampling (technique used in which research participants are asked to identify other potential participants) and social media platforms were used to acquire a …

Measuring Technical Super-Efficiency Of Christian Faith-Based International Humanitarian Organizations, Barbara G. Price

Doctoral Dissertations and Projects

COVID-19 left a wake of destruction upon its descension, pervasion, and diffusion across the continents. Not only did this happen at individual, household, and corporate levels, but also the nonprofit world. Christian ministries, faith-based organizations, and faith-based charities are among some of the largest international relief and development agencies that are on the front lines of humanitarian and disaster relief efforts (MinistryWatch & Smith, 2023). Understanding the effects of COVID-19 or phenomena with similar magnitudes on faith-based organizations is critical to understanding the impact at the level of their international humanitarian development and relief programs. There is a need for …

A Qualitative Examination Of Food Choice Among Division Iii Student Athletes Using Grounded Theory, Paul Webster Craig

Doctoral Dissertations and Projects

The determinants of food choice among the general population have been extensively investigated, but studies of food choice in collegiate student athletes are limited. Student athletes make food choices daily, and the selection of foods is an integral part of an athlete’s training regimen. National Collegiate Athletic Association (NCAA) Division III (DIII) student athletes are a comparatively unstudied population, particularly in terms of their food choices; therefore, assessing and understanding the influences of food choices in this population can enable and support optimal eating behavior. To assess different determinants of food choice in athletes, this qualitative study developed a theoretical …

Teacher Retention: A Phenomenological Study On The Experiences Of White Male Teachers In An Urban Secondary School, Bryce M. Woerner

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to discover the commonalities and factors of retention for White male teachers at an urban secondary school. The focus was on the experiences of the White male teachers at an urban secondary school in Virginia. This research is an examination of the experiences and perceptions of White male teachers. The data included interviews, focus groups, and letter writing to fill the gap in literature for teacher retention in urban schools. The research questions included what are the lived experiences of White male teachers in urban secondary schools and why do they choose …

Who Or What Is Worthy Of Our Loyalty?, Philosophical Discussion Group

The Philosopher's Stone

No abstract provided.

Mitigating Patient Violence Within Inpatient Psychiatric Facilities, Jeremiah Smith

Walden Dissertations and Doctoral Studies

Psychiatric facilities have a high rate of violence against staff and patients, resulting in negative consequences for the organization. The purpose of this integrative review is to search the existing body of knowledge regarding violence risk assessment (VRA) tools and their ability to function as a resource used to monitor conditions (patient behaviors) within the psychiatric environment in efforts to mitigate patient violence. VRA tools have been found to minimize violence in the workplace by enhancing staff awareness and serving as a resource used to collect information and assist in implementing effective interventions. An integrative review was conducted consisting of …

Improving Emergency Department Utilization Rates And Quality Of Health Among Uninsured Hispanics, Astrid M. Escalante Leon

Walden Dissertations and Doctoral Studies

Solutions are needed to address the overutilization of emergency departments (EDs) for ongoing and non-emergency conditions among uninsured Hispanic patients. The purpose of this review was to synthesize available evidence related to hospital utilization rates for non-emergency conditions and quality of health and to provide strategies for leaders to reduce ED utilization rates for uninsured Hispanics. An integrative review was conducted of existing literature published between 2020 and 2024. Thematic analysis identified four significant themes: (a) insurance coverage, (b) high-risk uninsured patients, (c) ED, and (d) healthcare payment models. The 12 subthemes identified were (a) non-expansion Medicaid states, (b) delay …

Practical Insights And Advances In Concrete Pumping, Daniil Mikhalev, Siamak Fakhrayee Nejad, Serina Ng, Baishakhi Bose, Robin De Schryver, Ana Brunčič, Manu K. Mohan, Yanwei Wang, A. V. Rahul, Atta Ur Rehman, Dengwu Jiao, Viktor Mechtcherine, Geert De Schutter, Dimitri Feys

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

This technical letter gives a concise overview of the state-of-the-art in concrete pumping. It outlines the different pump systems, briefly describes the general flow behavior of concrete in pipes and addresses the main challenges of pumping. It also elaborates upon factors influencing the pumping behavior and how to control the pumping process.

Four Thirty Realty Llc V. Kamal

All Decisions

The tenant appealed the denial of her motion to amend the answer in a nonpayment summary proceeding. The tenant sought to include a set-off and counterclaim based on violations issued by the Department of Buildings. The appellate court reversed the lower court's decision, granting the tenant's motion and deeming the proposed amended answer served and filed. The court found that the landlord failed to show surprise or prejudice and that the proposed amendment was not palpably insufficient or patently devoid of merit.

Experiences Of South Carolina Middle School Music Directors Teaching Multicultural Music In Performance Classes: A Multiple Case Study, Helen Bryan Terlizzi

Doctoral Dissertations and Projects

The purpose of this multiple case study was to discover the experiences of middle school music directors in providing multicultural music performance experiences for students in South Carolina. The theory guiding this study was Cultural-Historical Activity Theory as it allowed for the examination of tools used for teaching and learning. A qualitative multiple case study design allowed for the collection of data from four purposefully selected middle schools in South Carolina. The study sought to answer the central research question: How do music educators describe their experiences in teaching multicultural music in music performance classes? The focus of the research …