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Poetic Lines And Social Thought, Adam Neikirk

Contemporary Aesthetics (Journal Archive)

This article draws connections between formal poetry and the capacity to imagine not just the actual world, but any possible world as essentially peopled and peopled with others: both human and nonhuman intelligences. Beginning with an anecdote from the fringes of science, the author goes on to identify the presence of social thought in Romantic literary worlds, citing canonical poems that rely on the recursion of metrical lines such as “Mont Blanc” (Percy Bysshe Shelley) and “Kubla Khan” (Samuel Taylor Coleridge). A theory of poetic lines is then proffered in which poetic invention is related strongly to the idea of …

First Principles Materials Discovery And Design For Photovoltaic And Solar Thermal Alloys Using High Throughput Methods, Andrew Pike

Dartmouth College Ph.D Dissertations

Materials selection has been a challenge since the dawn of time. With the advent of computational methods and high throughput databases, materials can be discovered and assessed before they are even synthesized. In this thesis I will discuss my work towards designing new materials for clean energy uses, especially alloys which have been underexplored from computational methods. To begin, I present a case study explaining the synthesis of the Yb₁₄ZnSb₁₁ thermoelectric material. Next, I explore the class of AM₂Pn₂ Zintl materials. From the previously identified BaCd₂P₂, it is suspected that …

Robert W. Mcmullin, Myrna J. Layton

Faculty Publications

Robert Wesley McMullin (April 29, 1921 – January 3, 1995) was a Canadian composer, conductor, instrumentalist and music director. While he was born into a Mormon family in Utah, he was a proud Canadian: in a 1965 interview with Canadian Composer, he said: “The brain drain to the United States is a bad thing. It reduces our chances of arriving at a distinctive Canadian art form.” He composed works for orchestra, band, and piano, but the bulk of his compositions were for radio or television programming. Later in his career, he scored several films.

Conventional Versus Advanced Imaging Selection For Endovascular Treatment Of Basilar Artery Occlusion Strokes, Conor Cunningham, Ilko Maier, Sami Al Kasab, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M Starke, Marios-Nikos Psychogios, Edgar A Samaniego, Nitin Goyal, Shinichi Yoshimura, Hugo Cuellar, Jonathan A Grossberg, Ali Alawieh, Ali Alaraj, Mohamad Ezzeldin, Daniele G Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Fazeel Siddiqui, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S Park, Michael R Levitt, Waleed Brinjikji, Mark Moss, Travis Dumont, Ergun Daglioglu, Richard Williamson, Pedro Navia, Reade De Leacy, Shakeel Chowdhry, David J Altschul, Alejandro M Spiotta, Peter Kan

Faculty, Staff and Students Publications

Introduction: Endovascular thrombectomy (EVT) is an effective treatment for basilar artery occlusion (BAO) stroke in select patients. While there is a growing body of literature suggesting that advanced imaging modalities such as computed tomography perfusion (CTP) and magnetic resonance (MR) may not be necessary for selecting anterior circulation large vessel occlusion stroke patients for EVT, whether advanced imaging may be superior to conventional imaging (non-contrast CT and CT angiography) in identifying good treatment candidates among BAO patients is less clear.

Patients and methods: This was a multicenter retrospective cohort study of BAO EVT patients treated from 2013 to 2022 in …

Understanding The Why: Patient, Parent, And Oncologist Perspectives On Prognostic Communication Preferences In Advanced Childhood Cancer, Harmony Farner, Shoshana Mehler, Caroline Christianson, Erica C Kaye

Faculty, Staff and Students Publications

Background/objectives: High-quality prognostic communication in pediatric oncology is essential to support informed decision making, foster trust, and honor goals of care. While families differ in their preferences for how prognosis is discussed, clinicians often rely on assumptions rather than directly eliciting these preferences, risking misalignment and distress. To address this gap, we aimed to characterize patient, parent, and oncologist perspectives on key variables, experiences, and circumstances that influence their preferences for prognostic communication.

Methods: Semi-structured interviews were conducted with 85 participants (25 patients aged 12-25, 40 parents, and 20 oncologists) to elicit their preferences for prognostic communication and the reasons …

C-C Motif Chemokine Receptor-Like 2 Promotes The Interferon-Γ Signaling Response In Myeloid Neoplasms With Erythroid Differentiation And Mutated Tp53, Pablo Toledano-Sanz, Joseph Rimando, Yuju An, Yashvi Hemani, Brandy Perkins, Xinghan Zeng, Conover Talbot, Bogdan Paun, Abdulmuez Abdulmalik, Chen Lossos, Tatianna R Boronina, Ilias Sinanidis, Panagiotis Tsakiroglou, Priyanka Fernandes, Christopher Esteb, Alexander J Ambinder, Robert N Cole, Rena Xian, Ivana Gojo, Suman Paul, Mark J Levis, Amy E Dezern, Leo Luznik, Styliani Karanika, Linda S Resar, Richard J Jones, Frederick Bunz, Lukasz Gondek, Marios Arvanitis, Theodoros Karantanos

Faculty, Staff and Students Publications

Patients with myeloid neoplasms with loss-of-function TP53 mutations and erythroid differentiation have poor outcomes, and a better understanding of disease biology is required. Upregulation of interferon-γ (IFN-γ) signaling has been associated with acute myeloid leukemia (AML) progression, selection of TP53 mutated clones and chemotherapy resistance, but its drivers remain unclear. In this study, we found that the surface receptor C-C motif chemokine receptor-like 2 (CCRL2) is overexpressed in AML with erythroid differentiation and TP53 mutations compared to other AML subtypes and healthy hematopoietic cells. CCRL2 knockout (KO) suppressed erythroleukemia growth in vitro and in vivo. Further proteomics and transcriptomics analysis …

Hiv-1 Controllers Possess A Unique Cd8+ T Cell Activation Phenotype And Loss Of Control Is Associated With Increased Expression Of Exhaustion Markers, Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

BACKGROUND: HIV-1 controllers are a rare population of individuals that exhibit spontaneous control of HIV-1 infection without antiretroviral therapy. Understanding the mechanisms by which HIV-1 controllers maintain and eventually lose this ability would be highly valuable in HIV-1 cure or vaccine research. Previous work revealed the ability of CD8+ T cells isolated from HIV-1 controllers to suppress HIV-1 replication in matched CD4+ T cells and PBMCs ex vivo and suggested the loss of control may be tied to CD8+ T cell exhaustion.

RESULTS: We explored whether CD8+ T cell exhaustion plays a role in the maintenance and loss of control …

Dna Double-Stranded Breaks, A Hallmark Of Aging, Defined At The Nucleotide Resolution, Are Increased And Associated With Transcription In The Cardiac Myocytes In Lmna-Cardiomyopathy, Priyatansh Gurha, Ali J Marian

Faculty, Staff and Student Publications

Aims: An intrinsic feature of gene transcription is the formation of DNA superhelices near the transcription bubble, which are resolved upon induction of transient double-stranded breaks (DSBs) by topoisomerases. Unrepaired DSBs are pathogenic as they lead to cell cycle arrest, senescence, inflammation, and organ dysfunction. We posit that DSBs would be more prevalent at the genomic sites that are associated with gene expression. The objectives were to identify and characterize genome-wide DSBs at the nucleotide resolution and determine the association of DSBs with transcription in cardiac myocytes.

Methods and results: We identified the genome-wide DSBs in ∼1 million cardiac myocytes …

Electricity And The Environment, Praveen Kumar

Doctoral Theses

This thesis explores the intersection of electricity and the environment across three studies. The first study examines the 2018 policy in Telangana that removed agricultural electricity rationing, providing farmers with 24-hour power. Using detailed panel data and a difference-in-differences approach, the study finds a 53% rise in agricultural electricity consumption and an expansion of water-intensive rice cultivation relative to boundary districts in neighboring states. However, no statistically significant change is detected in groundwater depth measured by government monitoring wells, suggesting that current monitoring systems may not adequately capture water availability in fragmented hard-rock aquifers. The second study evaluates a subsidized …

Mantle Flow And Fault Zone Related Seismic Anisotropy Revealed By A Dense Linear Broadband Array In Southeast Tibet, Jing Wu, Yinshuang Ai, Stephen S. Gao, Peixi Huang, Fansheng Kong, Deke Xu, Jianguo Song, Xinyu Gao, Mengyi Wei, Long Li, Jien Zhang, Yanbin Zhang, Yingying Zhang

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Southeast Tibet, a key region for the southeastward extrusion of the Tibetan Plateau, remains debated in terms of its tectonic deformation in response to the ongoing collision between the Indian and Eurasian plates. In this study, we applied shear-wave splitting analysis of core-refracted phases recorded by a newly deployed dense seismic array and six permanent stations to delineate crustal and mantle deformation processes. The observed fast polarization directions are predominantly aligned NNW–SSE, while the splitting delay times vary across four sub-blocks. The anisotropy pattern suggests a dominantly asthenospheric origin, consistent with southeastward-directed mantle flow associated with the extrusion of the …

Faculty Senate Agenda, Georgia Southern University, Faculty Senate

Faculty Senate Agendas

No abstract provided.

Faculty Senate Minutes, Georgia Southern University, Faculty Senate

Faculty Senate Minutes

No abstract provided.

Rest Easy, Applied Researcher: Latent Profile Analysis Is For You, Matthew A. Ng, Chelsea A. Lenoble, Allen Shorey, Abigale Gregory, Mark Kateli

Psychological Science Faculty Research & Creative Works

No abstract provided.

Strategies To Improve Project Portfolio Management In The Pharmaceutical Industry, Emely Nhi Thi Ai Nguyen

Walden Dissertations and Doctoral Studies

Poor management of pharmaceutical project portfolios can negatively impact a pharmaceutical company’s product development and profitability. Project portfolio managers must ensure the successful development of new products in the pharmaceutical pipeline as the financial investment in new product development is significant and if not managed effectively can negatively impact profitability and prevent launch of new treatment therapies. Grounded in the project portfolio management framework, the purpose of this qualitative pragmatic inquiry study was to explore successful project portfolio management (PPM) strategies that drug project portfolio managers use to contribute to business success. The participants were six employees that managed portfolios …

Alterations In Ether Lipid Metabolism In Obesity Revealed By Systems Genomics Of Multi-Omics Datasets, Yvette Schooneveldt, Sudip Paul, Kevin Huynh, Habtamu B. Beyene, Natalie A. Mellett, Gerald F. Watts, Joseph Hung, Jennie Hui, John Beilby, John Blangero

Human Genetics Publications

Ratios between two metabolites are sensitive indicators of metabolic changes. Lipidomic profiling studies have revealed that plasma ether lipids, a class of glycero- and glycerophospho-lipids with reported health benefits, are negatively associated with obesity. Here, we utilized lipid ratios as surrogate markers of lipid metabolism to explore the processes underlying the inverse relationship between ether lipid metabolism and obesity. Plasma lipidomics data from two independent human cohorts (n = 10,339 and n = 4,492) were integrated to assess the associations between 82 lipid ratios and obesity-related markers in males and females. Results were externally validated using mouse transcriptomics data …

Safe Nurse Staffing For Scotland: A Cross-Sectional Observational Study, Eileen T. Lake

Sigma Foundation for Nursing Research Grant Reports

Amid a global nurse staffing crisis, the project is designed to describe the baseline nursing standards adherence, nurse staffing, and work environments in hospitals before the April 2024 implementation of Scotland’s Safe Staffing Act 2019. Quantifying the variation is important to evaluate the Law’s subsequent implementation (whether hospitals meet standards) and impact (whether standards improve quality and safety). The results will aid policymakers by providing baseline data from Scotland before the Law is implemented and an informative exemplar for states and countries globally as many government authorities consider nurse staffing legislation.

Contradictory Role Of Forgiveness Against Undergraduate Students’ Online Game Addiction Tendency: Two Preliminary Studies Before And During The Covid-19 Pandemic, Amalia Rahmandani

Jurnal Kajian Bimbingan dan Konseling

Two quantitative and cross-sectional preliminary studies were conducted to address the issues of forgiveness in the context of the tendency to online game addiction among university students in Semarang, Indonesia. A forgiveness scale comprising three dimensions of forgiveness, including forgiveness of self, others, and situations, as well as two separate scales of the tendency to online game addiction, was used. Samples consisting of two groups of online gamers were obtained using a convenience sampling technique. The sample size of Study 1, conducted prior to the onset of the COVID-19 pandemic, was 114 participants (Male = 98.25%) from four game centers. …

Exploration Of Counselors’ Epistemology: Epistemic Style Perspectives In Helping Relationships, Muty Rachmadiny Utami, Nissa Aulia Belistiana Utami, Nandang Budiman

Jurnal Kajian Bimbingan dan Konseling

Epistemological studies provide important insights into how counselors build their knowledge related to the helping relationship through epistemic styles. This study aims to describe the epistemology of the helping relationship in counseling. A qualitative approach with a case study design was used to explore the experiences of guidance and counseling teachers and students as research participants. Data were collected through the analysis of counseling documents and semi-structured interviews with guidance and counseling teachers as well as five counselee participants. The study results discuss the epistemology of the helping relationship of counselors in seven themes: sources of counselor knowledge, the process …

Influence Of Child Abuse On Youth Restiveness As Perceived By Security Personnel In Ilorin Metropolis, Kwara State, Falilat Anike Okesina

Jurnal Kajian Bimbingan dan Konseling

The rate at which Nigerian youths take up arms to perpetuate anti-social acts has become a major concern to the populace. This study investigated the influence of child abuse on youth restiveness as perceived by security personnel in Ilorin metropolis, Kwara State. The study was a survey research. The population of this study comprised all security personnel in Ilorin metropolis and 200 respondents were randomly selected for the study. A questionnaire entitled “Influence of Child Abuse on Youths Restiveness Questionnaire” (ICAYRQ) was used to collect data for the study. Percentage was used to analyse the demographic data. Mean and rank …

The Impact Of Housing Stress On Fertility Intentions Among Young People In Urban China, Fei Ouyang

Lingnan Theses (MPhil & PhD)

Housing has been recognised as an important factor associated with decreasing fertility in urban China. Despite a growing number of studies dedicated to the investigation of the impact of adverse housing conditions on fertility intentions, the understanding of housing-fertility nexus remains relatively fragmented, characterised by an incomplete picture of housing stressors and conflicting findings that fail to explain why some people experiencing adverse housing conditions tend to have lower fertility intentions whilst others do not. Framing the transactional theory of stress into the housing contexts, this study redefined housing stress to enhance its explanation compared with correlation explanations in the …

Feasibility Evaluation Of Secure Offline Large Language Models With Retrieval-Augmented Generation For Cpu-Only Inference, Erick Tyndall, Torrey J. Wagner, Colleen Gayheart, Alexandre Some, Brent T. Langhals

Faculty Publications

Recent advances in large language models and retrieval-augmented generation, a method that enhances language models by integrating retrieved external documents, have created opportunities to deploy AI in secure, offline environments. This study explores the feasibility of using locally hosted, open-weight large language models with integrated retrieval-augmented generation capabilities on CPU-only hardware for tasks such as question answering and summarization. The evaluation reflects typical constraints in environments like government offices, where internet access and GPU acceleration may be restricted. Four models were tested using LocalGPT, a privacy-focused retrieval-augmented generation framework, on two consumer-grade systems: a laptop and a workstation. A technical …

Peptide-Based Inorganic Nanoparticles As Efficient Intracellular Delivery Systems, Amir Nasrolahi Shirazi, Rajesh Vadlapatla, Ajoy Koomer, Anthony Nguyen, Vian Khoury, Keykavous Parang

Pharmacy Faculty Articles and Research

Background/Objectives: Peptide-based inorganic nanoparticles (PINPs) have emerged as promising candidates for intracellular delivery due to their unique structural and functional attributes. These hybrid nanostructures combine the high surface area and tunable optical/magnetic properties of metal cores (e.g., Au, Ag, Fe3O4) with the biocompatibility, targeting specificity, and responsive behavior of peptides. In particular, peptides with amphipathic or cell-penetrating features could facilitate efficient transport of molecular cargos across cellular membranes while enabling stimulus-responsive drug release in target tissues. Methods: We review key synthesis methods (especially green, peptide-mediated one-pot approaches), functionalization strategies (e.g., thiol-gold bonds, click chemistries), and characterization techniques (TEM, …

Design And Optimization Of Anode Catalysts For Direct Ethanol Fuel Cells: Advances And Challenges In C-C Bond Activation And Selective Modulation Of The C1 Pathway, Kai-Chi Qin, Meng-Tian Huo, Yu Liang, Si-Yuan Zhu, Zi-Hao Xing, Jin-Fa Chang

Journal of Electrochemistry

Direct ethanol fuel cells (DEFCs) are a promising alternative to conventional energy sources, offering high energy density, environmental sustainability, and operational safety. Compared to methanol fuel cells, DEFCs exhibit lower toxicity and a more mature preparation process. Unlike hydrogen fuel cells, DEFCs provide superior storage and transport feasibility, as well as cost-effectiveness, significantly enhancing their commercial viability. However, the stable C–C bond in ethanol creates a high activation energy barrier, often resulting in incomplete electrooxidation. Current commercial platinum (Pt)- and palladium (Pd)-based catalysts demonstrate low C–C bond cleavage efficiency (

The Birnirk To Thule Transition As Viewed From Radiocarbon And Tree-Ring Dating Within Two Adjacent Houses At Cape Espenberg, Northwest Alaska, Claire Alix, Lauren E. Y. Norman, Antony M. Krus, Juliette Taieb, Shelby L. Anderson, Dennis H. O'Rourke, Owen K. Mason

Anthropology Faculty Publications and Presentations

The transformation of the Birnirk culture into the Thule culture is essential in reconstructing the emergence of modern Inuit across Alaska and the larger Bering Strait. To this end, two adjacent semi-subterranean houses of late Birnirk and early Thule affiliation, respectively, at the Rising Whale (KTZ-304) site at Cape Espenberg were recently excavated and dated by radiocarbon and tree-ring measurements. We present the Bayesian analysis of the resulting large series of dates, demonstrating the lack of contemporaneity between the two features: the Birnirk house was occupied in the late twelfth to early thirteenth centuries AD, whereas the occupation of the …

Evolving Paradigms In Acute Myeloid Leukemia: Personalized Approaches To Therapy Across Age And Risk Groups, Sumeet Yadav, Utsav Joshi, Guleid Hussein, Mohamed Warsame, Bolun Liu, Abhash Shrestha, Peter Krastev, Hariprasad Reddy Korsapati, Amrit Singh

Student Publications

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by the clonal proliferation of myeloid precursors and rapid progression. Historically consisting of intensive chemotherapy, AML management has evolved significantly due to advances in molecular diagnostics and risk stratification. This review discusses current therapeutic paradigms in AML, emphasizing the growing role of personalized medicine across age and risk groups. For younger, fit patients, intensive regimens such as the "7 + 3" protocol remain the standard, often enhanced by targeted agents like FMS-like tyrosine kinase 3 (FLT3) and IDH inhibitors. Older or unfit individuals benefit from low-intensity treatments such as hypomethylating …

Hydrosocial Ocean Commons: Offshore Wind Energy In Oregon, Bryce Ashlyn Sprauer

Dissertations and Theses

The ocean has been culturally and legally conceptualized as a commons, a space of subsistence inherited by all. Enclosure or privatization creates overlapping jurisdictions of ocean space. The ocean is also the world's most significant carbon capture, absorbing billions of tons of anthropogenic carbon dioxide since the Industrial Revolution. Now, the ocean offers an additional opportunity to decarbonize energy production and reduce greenhouse gas emissions through 'new frontiers' of offshore wind technology; however, this potential is entangled within neoliberalism. Offshore wind is entering a fragmented legal landscape where the social-legal process of ocean jurisdiction remains contested. As the "new frontier" …

August 28, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Time Ticks Slowly For Kidney Transplant Reform: Eskd Patient Challenges And Opportunities, Gregory P. Hess

College of Population Health Faculty Papers

No abstract provided.

Transparency And Openness In Scientific Publishing Among Malaysian Social Science Researchers, Noor Masliana Razlan

Student Works (2020-2029)

The global movement toward transparency and openness in scientific publishing (TOSP) has become integral in strengthening research integrity, accessibility, and reproducibility. While TOSP practices are increasingly embedded in science, technology, engineering, and mathematics (STEM) disciplines, their uptake remains limited and fragmented in the social sciences, especially within the Malaysian context. This study investigates how Malaysian social science researchers interpret, adopt, and implement TOSP practices, and how these are influenced by demographic variables such as age, gender, academic position, discipline, and research experience. Using a sequential mixedmethods approach, the study draws on qualitative interviews with 20 participants and survey responses from …

Editorial: Endocrine Imbalances Of Mineral Ions And Vitamins In Chronic Disease Pathogenesis, Mor-Li Hartman, Hosam G. Abdelhady, Mohammed S. Razzaque

School of Medicine Publications

No abstract provided.