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Faculty Senate Minutes, Georgia Southern University, Faculty Senate

Faculty Senate Minutes

No abstract provided.

Rest Easy, Applied Researcher: Latent Profile Analysis Is For You, Matthew A. Ng, Chelsea A. Lenoble, Allen Shorey, Abigale Gregory, Mark Kateli

Psychological Science Faculty Research & Creative Works

No abstract provided.

Strategies To Improve Project Portfolio Management In The Pharmaceutical Industry, Emely Nhi Thi Ai Nguyen

Walden Dissertations and Doctoral Studies

Poor management of pharmaceutical project portfolios can negatively impact a pharmaceutical company’s product development and profitability. Project portfolio managers must ensure the successful development of new products in the pharmaceutical pipeline as the financial investment in new product development is significant and if not managed effectively can negatively impact profitability and prevent launch of new treatment therapies. Grounded in the project portfolio management framework, the purpose of this qualitative pragmatic inquiry study was to explore successful project portfolio management (PPM) strategies that drug project portfolio managers use to contribute to business success. The participants were six employees that managed portfolios …

Alterations In Ether Lipid Metabolism In Obesity Revealed By Systems Genomics Of Multi-Omics Datasets, Yvette Schooneveldt, Sudip Paul, Kevin Huynh, Habtamu B. Beyene, Natalie A. Mellett, Gerald F. Watts, Joseph Hung, Jennie Hui, John Beilby, John Blangero

Human Genetics Publications

Ratios between two metabolites are sensitive indicators of metabolic changes. Lipidomic profiling studies have revealed that plasma ether lipids, a class of glycero- and glycerophospho-lipids with reported health benefits, are negatively associated with obesity. Here, we utilized lipid ratios as surrogate markers of lipid metabolism to explore the processes underlying the inverse relationship between ether lipid metabolism and obesity. Plasma lipidomics data from two independent human cohorts (n = 10,339 and n = 4,492) were integrated to assess the associations between 82 lipid ratios and obesity-related markers in males and females. Results were externally validated using mouse transcriptomics data …

Safe Nurse Staffing For Scotland: A Cross-Sectional Observational Study, Eileen T. Lake

Sigma Foundation for Nursing Research Grant Reports

Amid a global nurse staffing crisis, the project is designed to describe the baseline nursing standards adherence, nurse staffing, and work environments in hospitals before the April 2024 implementation of Scotland’s Safe Staffing Act 2019. Quantifying the variation is important to evaluate the Law’s subsequent implementation (whether hospitals meet standards) and impact (whether standards improve quality and safety). The results will aid policymakers by providing baseline data from Scotland before the Law is implemented and an informative exemplar for states and countries globally as many government authorities consider nurse staffing legislation.

Contradictory Role Of Forgiveness Against Undergraduate Students’ Online Game Addiction Tendency: Two Preliminary Studies Before And During The Covid-19 Pandemic, Amalia Rahmandani

Jurnal Kajian Bimbingan dan Konseling

Two quantitative and cross-sectional preliminary studies were conducted to address the issues of forgiveness in the context of the tendency to online game addiction among university students in Semarang, Indonesia. A forgiveness scale comprising three dimensions of forgiveness, including forgiveness of self, others, and situations, as well as two separate scales of the tendency to online game addiction, was used. Samples consisting of two groups of online gamers were obtained using a convenience sampling technique. The sample size of Study 1, conducted prior to the onset of the COVID-19 pandemic, was 114 participants (Male = 98.25%) from four game centers. …

Exploration Of Counselors’ Epistemology: Epistemic Style Perspectives In Helping Relationships, Muty Rachmadiny Utami, Nissa Aulia Belistiana Utami, Nandang Budiman

Jurnal Kajian Bimbingan dan Konseling

Epistemological studies provide important insights into how counselors build their knowledge related to the helping relationship through epistemic styles. This study aims to describe the epistemology of the helping relationship in counseling. A qualitative approach with a case study design was used to explore the experiences of guidance and counseling teachers and students as research participants. Data were collected through the analysis of counseling documents and semi-structured interviews with guidance and counseling teachers as well as five counselee participants. The study results discuss the epistemology of the helping relationship of counselors in seven themes: sources of counselor knowledge, the process …

Influence Of Child Abuse On Youth Restiveness As Perceived By Security Personnel In Ilorin Metropolis, Kwara State, Falilat Anike Okesina

Jurnal Kajian Bimbingan dan Konseling

The rate at which Nigerian youths take up arms to perpetuate anti-social acts has become a major concern to the populace. This study investigated the influence of child abuse on youth restiveness as perceived by security personnel in Ilorin metropolis, Kwara State. The study was a survey research. The population of this study comprised all security personnel in Ilorin metropolis and 200 respondents were randomly selected for the study. A questionnaire entitled “Influence of Child Abuse on Youths Restiveness Questionnaire” (ICAYRQ) was used to collect data for the study. Percentage was used to analyse the demographic data. Mean and rank …

The Impact Of Housing Stress On Fertility Intentions Among Young People In Urban China, Fei Ouyang

Lingnan Theses (MPhil & PhD)

Housing has been recognised as an important factor associated with decreasing fertility in urban China. Despite a growing number of studies dedicated to the investigation of the impact of adverse housing conditions on fertility intentions, the understanding of housing-fertility nexus remains relatively fragmented, characterised by an incomplete picture of housing stressors and conflicting findings that fail to explain why some people experiencing adverse housing conditions tend to have lower fertility intentions whilst others do not. Framing the transactional theory of stress into the housing contexts, this study redefined housing stress to enhance its explanation compared with correlation explanations in the …

Feasibility Evaluation Of Secure Offline Large Language Models With Retrieval-Augmented Generation For Cpu-Only Inference, Erick Tyndall, Torrey J. Wagner, Colleen Gayheart, Alexandre Some, Brent T. Langhals

Faculty Publications

Recent advances in large language models and retrieval-augmented generation, a method that enhances language models by integrating retrieved external documents, have created opportunities to deploy AI in secure, offline environments. This study explores the feasibility of using locally hosted, open-weight large language models with integrated retrieval-augmented generation capabilities on CPU-only hardware for tasks such as question answering and summarization. The evaluation reflects typical constraints in environments like government offices, where internet access and GPU acceleration may be restricted. Four models were tested using LocalGPT, a privacy-focused retrieval-augmented generation framework, on two consumer-grade systems: a laptop and a workstation. A technical …

Peptide-Based Inorganic Nanoparticles As Efficient Intracellular Delivery Systems, Amir Nasrolahi Shirazi, Rajesh Vadlapatla, Ajoy Koomer, Anthony Nguyen, Vian Khoury, Keykavous Parang

Pharmacy Faculty Articles and Research

Background/Objectives: Peptide-based inorganic nanoparticles (PINPs) have emerged as promising candidates for intracellular delivery due to their unique structural and functional attributes. These hybrid nanostructures combine the high surface area and tunable optical/magnetic properties of metal cores (e.g., Au, Ag, Fe3O4) with the biocompatibility, targeting specificity, and responsive behavior of peptides. In particular, peptides with amphipathic or cell-penetrating features could facilitate efficient transport of molecular cargos across cellular membranes while enabling stimulus-responsive drug release in target tissues. Methods: We review key synthesis methods (especially green, peptide-mediated one-pot approaches), functionalization strategies (e.g., thiol-gold bonds, click chemistries), and characterization techniques (TEM, …

Design And Optimization Of Anode Catalysts For Direct Ethanol Fuel Cells: Advances And Challenges In C-C Bond Activation And Selective Modulation Of The C1 Pathway, Kai-Chi Qin, Meng-Tian Huo, Yu Liang, Si-Yuan Zhu, Zi-Hao Xing, Jin-Fa Chang

Journal of Electrochemistry

Direct ethanol fuel cells (DEFCs) are a promising alternative to conventional energy sources, offering high energy density, environmental sustainability, and operational safety. Compared to methanol fuel cells, DEFCs exhibit lower toxicity and a more mature preparation process. Unlike hydrogen fuel cells, DEFCs provide superior storage and transport feasibility, as well as cost-effectiveness, significantly enhancing their commercial viability. However, the stable C–C bond in ethanol creates a high activation energy barrier, often resulting in incomplete electrooxidation. Current commercial platinum (Pt)- and palladium (Pd)-based catalysts demonstrate low C–C bond cleavage efficiency (

The Birnirk To Thule Transition As Viewed From Radiocarbon And Tree-Ring Dating Within Two Adjacent Houses At Cape Espenberg, Northwest Alaska, Claire Alix, Lauren E. Y. Norman, Antony M. Krus, Juliette Taieb, Shelby L. Anderson, Dennis H. O'Rourke, Owen K. Mason

Anthropology Faculty Publications and Presentations

The transformation of the Birnirk culture into the Thule culture is essential in reconstructing the emergence of modern Inuit across Alaska and the larger Bering Strait. To this end, two adjacent semi-subterranean houses of late Birnirk and early Thule affiliation, respectively, at the Rising Whale (KTZ-304) site at Cape Espenberg were recently excavated and dated by radiocarbon and tree-ring measurements. We present the Bayesian analysis of the resulting large series of dates, demonstrating the lack of contemporaneity between the two features: the Birnirk house was occupied in the late twelfth to early thirteenth centuries AD, whereas the occupation of the …

Evolving Paradigms In Acute Myeloid Leukemia: Personalized Approaches To Therapy Across Age And Risk Groups, Sumeet Yadav, Utsav Joshi, Guleid Hussein, Mohamed Warsame, Bolun Liu, Abhash Shrestha, Peter Krastev, Hariprasad Reddy Korsapati, Amrit Singh

Student Publications

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by the clonal proliferation of myeloid precursors and rapid progression. Historically consisting of intensive chemotherapy, AML management has evolved significantly due to advances in molecular diagnostics and risk stratification. This review discusses current therapeutic paradigms in AML, emphasizing the growing role of personalized medicine across age and risk groups. For younger, fit patients, intensive regimens such as the "7 + 3" protocol remain the standard, often enhanced by targeted agents like FMS-like tyrosine kinase 3 (FLT3) and IDH inhibitors. Older or unfit individuals benefit from low-intensity treatments such as hypomethylating …

Hydrosocial Ocean Commons: Offshore Wind Energy In Oregon, Bryce Ashlyn Sprauer

Dissertations and Theses

The ocean has been culturally and legally conceptualized as a commons, a space of subsistence inherited by all. Enclosure or privatization creates overlapping jurisdictions of ocean space. The ocean is also the world's most significant carbon capture, absorbing billions of tons of anthropogenic carbon dioxide since the Industrial Revolution. Now, the ocean offers an additional opportunity to decarbonize energy production and reduce greenhouse gas emissions through 'new frontiers' of offshore wind technology; however, this potential is entangled within neoliberalism. Offshore wind is entering a fragmented legal landscape where the social-legal process of ocean jurisdiction remains contested. As the "new frontier" …

August 28, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Time Ticks Slowly For Kidney Transplant Reform: Eskd Patient Challenges And Opportunities, Gregory P. Hess

College of Population Health Faculty Papers

No abstract provided.

Transparency And Openness In Scientific Publishing Among Malaysian Social Science Researchers, Noor Masliana Razlan

Student Works (2020-2029)

The global movement toward transparency and openness in scientific publishing (TOSP) has become integral in strengthening research integrity, accessibility, and reproducibility. While TOSP practices are increasingly embedded in science, technology, engineering, and mathematics (STEM) disciplines, their uptake remains limited and fragmented in the social sciences, especially within the Malaysian context. This study investigates how Malaysian social science researchers interpret, adopt, and implement TOSP practices, and how these are influenced by demographic variables such as age, gender, academic position, discipline, and research experience. Using a sequential mixedmethods approach, the study draws on qualitative interviews with 20 participants and survey responses from …

Editorial: Endocrine Imbalances Of Mineral Ions And Vitamins In Chronic Disease Pathogenesis, Mor-Li Hartman, Hosam G. Abdelhady, Mohammed S. Razzaque

School of Medicine Publications

No abstract provided.

Adams Contribute To Triple Negative Breast Cancer Via Mtorc1 Pathway: Targeting Adam-Mtor Axis Improves Efficacy, Shuying Liu, Huiqin Chen, Mihai Gagea, Lorenzo Federico, Fan Zhang, Kim-Anh Do, Gabriel N Hortobagyi, Gordon B Mills, Ana M Gonzalez-Angulo, Debasish Tripathy

Faculty, Staff and Student Publications

Breast cancer is the most frequently diagnosed cancer globally and the second leading cause of cancer-related deaths in American women. Triple-negative breast cancer (TNBC) lacks estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2. Thus, fewer targeting therapies are available for this most aggressive subtype. The A Disintegrin and Metalloproteinase (ADAM) family plays a vital role in cancer pathophysiology. Previous studies focused on single ADAM members. However, none of these have entered into the clinical arena as diagnostics or therapeutics for breast cancer. In this study, we demonstrate the upregulation of a panel of ADAM members in TNBC, …

The Immunophenotypic And Genetic Characterization Of Pediatric T -L Ymphoblastic Leukemia With A Mature Immunophenotype, Mahsa Khanlari, Wei Wang, Parastou Tizro, Mohammad K Eldomery

Faculty, Staff and Student Publications

Not available.

Conventional Versus Advanced Imaging Selection For Endovascular Treatment Of Basilar Artery Occlusion Strokes, Huanwen Chen, Joshua Osbun, Et Al.

2020-Current year OA Pubs

INTRODUCTION: Endovascular thrombectomy (EVT) is an effective treatment for basilar artery occlusion (BAO) stroke in select patients. While there is a growing body of literature suggesting that advanced imaging modalities such as computed tomography perfusion (CTP) and magnetic resonance (MR) may not be necessary for selecting anterior circulation large vessel occlusion stroke patients for EVT, whether advanced imaging may be superior to conventional imaging (non-contrast CT and CT angiography) in identifying good treatment candidates among BAO patients is less clear.

PATIENTS AND METHODS: This was a multicenter retrospective cohort study of BAO EVT patients treated from 2013 to 2022 in …

Bi-5756 Reduces Graft-Versus-Host Disease Through Cb1-Mediated Treg Upregulation, Sena Kim, Abdul-Jalil Dania, Sora Lim, Jaebok Choi

2020-Current year OA Pubs

Cannabinoid receptor 1 (CB1) has been implicated in multiple inflammatory diseases by regulating pro-inflammatory mediators or altering immune cell polarization. However, the expression and direct functional role of CB1 in T cells remain largely unexplored. Here, we demonstrate that primary murine T cells express CB1 and that its novel agonist, BI-5756, directly increases the frequencies of regulatory T cells (Tregs) in primary murine pan T cells after activation. In addition, BI-5756 exhibits an in vivo protective effect against graft-versus-host disease (GvHD), an allogeneic T cell-mediated inflammatory complication after allogeneic hematopoietic cell transplantation (allo-HCT), resulting in an improved overall survival with …

Methane Partial Oxidation With Ni-Mg-Al Hydrotalcites: Impact Of Magnesium On Catalyst Performance, Dalia A. Ali Dr.

Chemical Engineering

The partial oxidation of methane (POM) is a promising route for hydrogen-rich syngas production with lower energy requirements compared to steam reforming. Herein, Ni-incorporated Mg-Al hydrotalcite- derived mixed oxide catalysts (5Ni-HT-x, x = 60, 65, 70, 75 wt.% Mg) were synthesized via co-precipitation and evaluated for CH₄ conversion and H₂ yield. Characterization techniques, including X-ray Diffraction (XRD), X-ray Photoelectron Spectroscopy (XPS), BET, H₂-TPR, TEM, FTIR, TGA, and Raman spectroscopy, were employed to investigate catalyst structure, active site stability, and carbon deposition. As a constituent of hydrotalcite-derived mixed oxides (HT), Ni2+ is strongly bound within the hydrotalcite- derived mixed oxides structure, …

Staff Education Project For Enhancing Medication Adherence In Mental Health: An Evidence-Based Education Program For Healthcare Practitioners In Outpatient Clinics, Rita Erina Pyuzza

Walden Dissertations and Doctoral Studies

The staff education project was designed to address medication non-adherence among mental health patients in an outpatient psychiatric clinic by enhancing the knowledge and skills of mental health nurses and nurse practitioners. The lack of structured, evidence-based training on medication adherence strategies has contributed to poor patient outcomes, increased hospitalizations, and higher healthcare costs. Clinic patient reports indicated 50% medication non-adherence, highlighting the need to address non-adherence through effective nursing-led education, medication management, and adherence monitoring. The project assessed whether enhancing the outpatient healthcare providers’ skills and knowledge through a structured, evidence-based program would improve the providers’ medication adherence strategies. …

Timely Resection Of Juvenile Nasopharyngeal Angiofibroma Following Embolization For Uncontrolled Acute Epistaxis Case Report., Koffi L. Lakpa, Timothy Mcculloch, Michael D. Puricelli

Manuscripts, Articles, Book Chapters and Other Papers

Uncontrolled epistaxis in patients with juvenile nasopharyngeal angiofibroma requires prompt intervention. When embolization is required, neovascularization can occur, making expedited surgical resection essential. We conducted a single-institution, retrospective review of one patient. This case study details the patient's clinical presentation and his preoperative, intraoperative, and postoperative course. We present the management of a 14-year-old male with a juvenile nasopharyngeal angiofibroma, who 3 days after initial evaluation at our institution, developed uncontrolled epistaxis requiring embolization at an outside hospital before transfer back to our institution for further management. He initially presented to an outside emergency department with acute epistaxis refractory to …

Adult-Child Caregivers’ Fear And Coping Regarding The Risk Of Inheriting Alzheimer’S Disease, Rebecca Anne Ledbetter

Walden Dissertations and Doctoral Studies

Caring for elderly parents with Alzheimer’s disease (AD) poses two major challenges for adult-child caregivers: the tasks involved in taking care of ailing parents and also potentially living in fear of developing the same disease. This research examined how caregivers with such fear regard their vulnerability to AD and how they manage the stress that comes with caregiving for someone with a disease they dread developing themselves. This grounded theory study employed the appraisal theory of emotions and the theory of moods as frameworks and aimed to establish awareness regarding coping strategies that adult-child caregivers have about caretaking and their …

Blood Culture Contamination Rates, Jackqueline R. Easley

Walden Dissertations and Doctoral Studies

The timely and accurate collection of blood culture specimens is essential for improving patient outcomes and minimizing complications. Contaminated specimens can lead to unnecessary antibiotic use, prolonged hospital stays, and delays in appropriate treatment. At one eastern healthcare facility, monthly blood culture contamination rates reached an average of 4.5%, prompting the need for a targeted intervention. The objective of this project was to determine whether a structured process and trained team could reduce contamination rates to below 1%. De-identified data were reviewed using descriptive statistics to observe contamination trends over time, by department, and by month. Using the t-test, contamination …

Staff Education On Perinatal Opioid Use Disorder, Mukisha Livingston Gunter

Walden Dissertations and Doctoral Studies

Perinatal Opioid Use Disorder (POUD) constitutes a significant public health issue with important ramifications for both mothers and their newborns. The gap in practice identified for this Doctor of Nursing Practice staff education project was the perinatal nurses’ lack of knowledge regarding POUD. The problem was the need for POUD education for the nurses. The practice focus questions were: Will there be a change in knowledge by perinatal nurses following the delivery of the education as shown by a pretest/posttest? Will the participants evaluate the education as having met the program objectives related to the curriculum presented? Guided by the …

Staff Education On Discharge Planning For A County Crisis Stabilization Unit, Eric Rowshaun Luster

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project was a staff education initiative developed to address insufficient staff knowledge related to discharge planning for homeless individuals experiencing mental health crises. The purpose of the project was to examine whether enhanced staff training could improve knowledge of transitional care planning, thereby supporting equitable, safe, and inclusive discharge processes. By improving staff proficiency, the project sought to reduce gaps in care coordination and promote continuity of treatment for a highly vulnerable patient population. The project was implemented at a Crisis Stabilization Unit (CSU) in the southern United States that serves individuals experiencing homelessness, …