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Articles 112471 - 112500 of 5150921

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Longitudinal Pharmacokinetic And Safety Studies Of An Antibody-Erythropoietin Fusion Protein For Alzheimer's Disease, Rudy Chang, Devaraj Venkatapura Chandrashekar, G. Chuli Roules, Nataraj Jagadeesan, Emi Iwasaki, Adenike Oyegbesan, Hayk Davtyan, Rachita K. Sumbria Dec 2025

Longitudinal Pharmacokinetic And Safety Studies Of An Antibody-Erythropoietin Fusion Protein For Alzheimer's Disease, Rudy Chang, Devaraj Venkatapura Chandrashekar, G. Chuli Roules, Nataraj Jagadeesan, Emi Iwasaki, Adenike Oyegbesan, Hayk Davtyan, Rachita K. Sumbria

Pharmacy Faculty Articles and Research

Erythropoietin (EPO) shows promise for Alzheimer's disease (AD) but has poor brain penetration, necessitating high doses that cause hematopoietic side effects. To improve brain delivery, EPO was fused to a transferrin receptor monoclonal antibody (TfRMAb), and this study evaluated the pharmacokinetics (PK), safety, and efficacy of repeated TfRMAb-EPO dosing in mice to further its preclinical development. C57BL/6J male mice (10 weeks old, n = 4–5/dose) received subcutaneous (SQ) low (1 mg/kg), mid (3 and 6 mg/kg), or high (20 mg/kg) TfRMAb-EPO doses for 4 weeks. The 1 mg/kg dose showed no adverse effects and resulted in sustained brain and plasma …


Genomic Surveillance Uncovers Regional Variation In Hcv Transmission Networks In Rural United States, Damien C. Tully, David J. Bean, Jacklyn Sarette, Thang Long Ngo, Karen A. Power, Daniel Brook, Hannah Cooper, Judith Feinberg, Peter D. Friedmann, Karli R. Hochstatter, Jennifer R. Havens, Shanna Babalonis, Christopher Hurt, Wiley Jenkins, P. Todd Korthuis, William Miller, Mai T. Pho, Gordon Smith, Thomas J. Stopka, Judith I. Tsui, L. Sarah Mixson, Ryan P. Westergaard, April M. Young, Todd M. Allen Dec 2025

Genomic Surveillance Uncovers Regional Variation In Hcv Transmission Networks In Rural United States, Damien C. Tully, David J. Bean, Jacklyn Sarette, Thang Long Ngo, Karen A. Power, Daniel Brook, Hannah Cooper, Judith Feinberg, Peter D. Friedmann, Karli R. Hochstatter, Jennifer R. Havens, Shanna Babalonis, Christopher Hurt, Wiley Jenkins, P. Todd Korthuis, William Miller, Mai T. Pho, Gordon Smith, Thomas J. Stopka, Judith I. Tsui, L. Sarah Mixson, Ryan P. Westergaard, April M. Young, Todd M. Allen

Epidemiology and Environmental Health Faculty Publications

Hepatitis C virus (HCV) remains a public health concern in the United States, particularly in rural communities where the opioid epidemic accelerates transmission among people who use drugs (PWUD). Despite this growing burden, the genetic features and transmission dynamics of HCV in these settings are poorly understood. We analyze 692 HCV antibody-positive specimens collected from rural communities in ten U.S. states using amplicon-based deep sequencing and the Global Hepatitis Outbreak and Surveillance Technology (GHOST) platform to reconstruct transmission networks. Among sequenced individuals, 29.5% are linked within clusters. Cluster structure varies by region from sparse networks in Ohio to dense clusters …


Redefining Resistance: Las Madres De La Plaza De Mayo, Echoes Of Trauma And Memory In Argentina, Elizabeth J. Kaye Dec 2025

Redefining Resistance: Las Madres De La Plaza De Mayo, Echoes Of Trauma And Memory In Argentina, Elizabeth J. Kaye

Honors Theses

Argentina's "Dirty War" (1976–1983) stands as one of the darkest and most painful periods in the nation’s history. During these years, the military dictatorship, known as the "Proceso de Reorganización Nacional," implemented a systematic campaign of state terrorism, targeting suspected political protesters, activists, intellectuals, and ordinary citizens. Widespread kidnappings, illegal detentions, and forced disappearances became routine, with an estimated 30,000 people vanishing without a trace. Families were left in despair, searching for answers that the government refused to provide. In response, a group of determined mothers, known as “Las Madres de la Plaza de Mayo”, formed a powerful movement demanding …


The George-Anne Daily, Georgia Southern University Dec 2025

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


State Of Nevada Cannabis Testing, University Of Mississippi – National Center For Cannabis Research And Education, Yasha Kahn, Mcr Labs Dec 2025

State Of Nevada Cannabis Testing, University Of Mississippi – National Center For Cannabis Research And Education, Yasha Kahn, Mcr Labs

Nevada

No abstract provided.


State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education Dec 2025

State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education

California

No abstract provided.


Resolution On Response To Campus Threats, Jeff Stowell Dec 2025

Resolution On Response To Campus Threats, Jeff Stowell

Faculty Senate Resolutions

This resolution is the work of multiple faculty on Faculty Senate and at large, and is a response to perceived gaps in campus safety protocols.


167 8th Ave. Llc V Goldstein Dec 2025

167 8th Ave. Llc V Goldstein

All Decisions

The Appellate Term reversed a money judgment and reinstated a tenant's rent overcharge defenses and counterclaims, remanding for reconsideration. While the appeal regarding possession was dismissed as moot due to the tenant's eviction, the monetary claims persisted. The court held that recent legislative amendments (L. 2024, Ch. 95 § 4) mandating a "totality of the circumstances" standard for fraudulent deregulation claims apply to pending cases. This new standard, more favorable to tenants, requires the lower court to determine if the landlord knowingly engaged in a fraudulent scheme to remove the apartment from rent stabilization.


Constitutional Law On Abortion In Latin America And The Caribbean: A Regional Consensus Towards An International Custom Or A Peremptory Norm Of Jus Cogens?, Ligia Castaldi Dec 2025

Constitutional Law On Abortion In Latin America And The Caribbean: A Regional Consensus Towards An International Custom Or A Peremptory Norm Of Jus Cogens?, Ligia Castaldi

University of Miami Inter-American Law Review

The Inter–American Court of Human Rights recently declared the existence of a jus cogens right to a healthy environment: could it lawfully reach the same conclusion regarding a right to abortion? This paper examines constitutional law and constitutional jurisprudence on abortion in Latin American and Caribbean countries to determine whether a regional consensus exists on abortion rights in the region. The paper looks at landmark abortion decisions favoring abortion rights in Colombia and Mexico, as well as broad abortion decriminalization through statutory reform in Argentina, Uruguay, Haiti and Cuba. The paper also looks at prenatal right to life protections in …


Extensions Of Weighted Integral Inequalities For Ga-Convex Functions In Connection With Fejér’S Result, Muhammad Amer Latif Dec 2025

Extensions Of Weighted Integral Inequalities For Ga-Convex Functions In Connection With Fejér’S Result, Muhammad Amer Latif

Publications and Research

No abstract provided.


Edna Surveys For The Critically Endangered Caribbean Staghorn Coral, Acropora Cervicornis (Lamarck, 1816), Pari Elaine Cribbins Dec 2025

Edna Surveys For The Critically Endangered Caribbean Staghorn Coral, Acropora Cervicornis (Lamarck, 1816), Pari Elaine Cribbins

All HCAS Student Capstones, Theses, and Dissertations

Historically, Acropora cervicornis was a dominant coral on Caribbean reef systems, but an outbreak of white band disease in the late 1970s marked the beginning of devastating, multi-decadal population declines that led to the coral being listed as “critically endangered” on the IUCN Red List in 2022. Today, after a record-setting marine heat wave in 2023 triggered a mass bleaching event on Florida’s Coral Reef (FCR), A. cervicornis is considered functionally extinct on the FCR. While individuals of A. cervicornis do remain on the FCR, the small population size of the coral makes in situ surveys difficult. However, surveys using …


A Burlesque: The Shimmering Body Of Revealing, Lola Montgomery Dec 2025

A Burlesque: The Shimmering Body Of Revealing, Lola Montgomery

Staff Scholarship - Australia & Dubai

A Burlesque: The Shimmer Manuscript is a hybrid critical–creative work that examines burlesque as an embodied methodology and a mode of knowledge production. Drawing from my two decades as a performer–scholar, the work reframes glamour, desire, and adornment as epistemological practices rather than theatrical ornamentation. The project is significant in that it expands understandings of performance studies, autotheory, and feminist aesthetics by foregrounding the performer’s body as an intelligent, sensing, world-making apparatus.

The methodology is creative practice research and archive-driven, integrating backstage documentation, AI-assisted photomontage, and theoretical reflection. The work draws from poststructuralist and feminist frameworks (Irigaray, Deleuze & Guattari, …


Breakfast-For-Dinner, New York Law School Dec 2025

Breakfast-For-Dinner, New York Law School

Miscellaneous Campus Flyers

Tuesday, December 2, 2025


Examining The Relationship Between School Location, Neighborhood Resources And Advancement Courses Offerings, Eudarius Jones Dec 2025

Examining The Relationship Between School Location, Neighborhood Resources And Advancement Courses Offerings, Eudarius Jones

Electronic Theses and Dissertations Archive

This study addresses a critical gap in educational equity research by examining how neighborhood-level factors intersect to shape access to rigorous academic programming, a key gateway to postsecondary success. Integrating geospatial visualization and hierarchical linear modeling within a critical geography framework, the study investigates how structural inequalities—rooted in race, poverty, and place—influence advanced course-taking opportunities across the Memphis metropolitan region. Data sources included the U.S. Department of Education’s Common Core of Data (CCD) for district-level enrollment and school type, the U.S. Census and American Community Survey (ACS) for demographic and socioeconomic indicators, and the National Center for Charitable Statistics (NCCS) …


December 2, 2025 Ereporter, University Of Alabama At Birmingham Dec 2025

December 2, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Deanna Scarbo V. Royal Athena Dec 2025

Deanna Scarbo V. Royal Athena

2025 Decisions

USDC for the Eastern District of Pennsylvania


Reducing Storage-Related Bias In Reproductive Vitamin D Research: Towards A Stable And Reliable Biomarker Of Ovarian Vitamin D Status, Evelin E Lara-Molina, Jason M. Franasiak, Almudena Devesa-Peiro, Marina López-Nogueroles, Alberto Vázquez, David Amorós, Agustín Ballesteros, Antonio Pellicer, Patricia Sebastian-Leon, Patricia Diaz-Gimeno Dec 2025

Reducing Storage-Related Bias In Reproductive Vitamin D Research: Towards A Stable And Reliable Biomarker Of Ovarian Vitamin D Status, Evelin E Lara-Molina, Jason M. Franasiak, Almudena Devesa-Peiro, Marina López-Nogueroles, Alberto Vázquez, David Amorós, Agustín Ballesteros, Antonio Pellicer, Patricia Sebastian-Leon, Patricia Diaz-Gimeno

SKMC Student Presentations and Publications

Background/Objectives: One of the main reasons for discrepancies in the role of vitamin D in ART could be the measurement of the conventional biomarker 25(OH)D3. It is known that this value is affected by multiple factors, such as tissue origin, assay variability, classification criteria, and potential storage-related degradation. In this study, we investigate 24,25(OH)2D3 as a new biomarker to improve vitamin D assessment in women’s reproductive health, particularly regarding oocyte development. Methods: A prospective cohort study including 35 oocyte donors undergoing controlled ovarian stimulation, who were recruited between October and November 2017, was conducted. Vitamin …


Cougar Closet Grand Opening Held Nov. 25, Communications And Marketing Dec 2025

Cougar Closet Grand Opening Held Nov. 25, Communications And Marketing

Campus News Archive

No abstract provided.


Cougars Have A Ball Painting Toys For Children In The Community, Communications And Marketing Dec 2025

Cougars Have A Ball Painting Toys For Children In The Community, Communications And Marketing

Campus News Archive

No abstract provided.


Ctrl + Alt + Inner Speech: A Verbal–Cognitive Scaffold (Vcs) Model Of Pathways To Computational Thinking, Daisuke Akiba Dec 2025

Ctrl + Alt + Inner Speech: A Verbal–Cognitive Scaffold (Vcs) Model Of Pathways To Computational Thinking, Daisuke Akiba

Publications and Research

This theoretical paper introduces the Verbal–Cognitive Scaffold (VCS) Model, a cognitively inclusive framework which proposes the cognitive architectures underlying computational thinking (CT). Moving beyond monolithic theories of cognition (e.g., executive-function and metacognitive control models), the VCS Model posits inner speech (InSp) as the predominant cognitive pathway supporting CT operations in neurotypical populations. Synthesizing interdisciplinary scholarship across cognitive science, computational theory, neurodiversity research, and others, this framework articulates distinct mechanisms through which InSp supports CT. The model specifies four primary pathways linking InSp to CT components: verbal working memory supporting decomposition, symbolic representation facilitating pattern recognition and abstraction, sequential processing enabling …


Curriculum Minutes 12/02/2025, Curriculum Committee Dec 2025

Curriculum Minutes 12/02/2025, Curriculum Committee

Curriculum Committee Minutes

No abstract provided.


Minutes, Curriculum Committee Meeting, Friday, December 02, 2025, Curriculum Committee Dec 2025

Minutes, Curriculum Committee Meeting, Friday, December 02, 2025, Curriculum Committee

Curriculum Committee Minutes

No abstract provided.


The George-Anne Dec 2025

The George-Anne

The George-Anne

No abstract provided.


Line Transect Surveys And Initial Estimates Of Abundance For Sea Turtles In Biscayne National Park, Florida., Kathryn C. Price Dec 2025

Line Transect Surveys And Initial Estimates Of Abundance For Sea Turtles In Biscayne National Park, Florida., Kathryn C. Price

All HCAS Student Capstones, Theses, and Dissertations

The loggerhead (Caretta caretta) and green (Chelonia mydas) turtle are two species of marine megafauna that have suffered abundance declines due to increased anthropogenic pressures. Assessing the distribution and abundance of sea turtles is essential for conserving and managing these imperiled species; however, assessing sea turtle populations poses difficulties due to the sea turtles’ highly migratory nature. Distance sampling surveys are extensively used to study populations of wide-ranging species. In this study, vessel-based line transect survey data collected throughout 2024 were used to estimate overall and seasonal sea turtle abundances and distribution throughout Biscayne National Park, …


What Is A Nativity Set?, Bridget Retzloff Dec 2025

What Is A Nativity Set?, Bridget Retzloff

Marian Library Blog Archive

Learn about a tradition that helps people to imagine the birth of Christ.


States As Shields, Lindsay F. Wiley Dec 2025

States As Shields, Lindsay F. Wiley

Minnesota Law Review Vols. 106:2 onward (2021-present)

State laws that aim to shield providers of reproductive health and gender-affirming care from the punitive actions of out-of-state officials raise thorny questions. Can the federal courts, Congress, or the Trump Administration require New York officials to enforce a Texas ban on abortion or gender-affirming care against a New York doctor who prescribed medication to a patient in Texas via telehealth? If so, how might New Yorkers’ access to health care be affected? If not, will interstate commerce and travel preserve some degree of access for Texans?

Disputes over reproductive health and gender-affirming care are putting new pressure on doctrines …


Quality Improvement Project: Provider Education On An Evidence-Based Clinical Pathway For Diagnosing Adult Attention-Deficit Hyperactivity Disorder, Oluwadayo B. Adeyemo Dec 2025

Quality Improvement Project: Provider Education On An Evidence-Based Clinical Pathway For Diagnosing Adult Attention-Deficit Hyperactivity Disorder, Oluwadayo B. Adeyemo

Doctor of Nursing Practice Projects

Accurate diagnosis of adult Attention-Deficit Hyperactivity Disorder (ADHD) remains challenging in outpatient behavioral health settings, as variations in clinician training, diagnostic tools, and assessment methods can hinder accuracy and delay treatment. At the project site, providers reported low confidence and inconsistent use of standardized tools when evaluating adult ADHD, underscoring a critical need for structured education to improve diagnostic consistency and provider confidence. This quality-improvement (QI) project assessed the impact of an educational intervention on provider knowledge, confidence, and utilization of validated screening tools for adult ADHD. Guided by Donabedian’s Model of Quality Improvement and Lewin’s Change Theory, the project …


Quality Improvement Project: The Impact Of Genetic Testing Education For Mental Health Providers In An Outpatient Clinic, Ifeoma Uzoh-Anigbogu Dec 2025

Quality Improvement Project: The Impact Of Genetic Testing Education For Mental Health Providers In An Outpatient Clinic, Ifeoma Uzoh-Anigbogu

Doctor of Nursing Practice Projects

Despite growing evidence supporting the use of genetic screening in psychiatric medication management, many mental health providers lack the confidence and knowledge to utilize this tool effectively. This quality improvement (QI) project aimed to enhance provider self-efficacy and increase the utilization of genetic screening through a structured education and training program in an outpatient mental health clinic. The purpose of the project was to determine whether provider education on pharmacogenetic testing improves confidence and screening frequency compared to those who do not receive the intervention. The Donabedian Model guided evaluation of structure, process, and outcome measures, while Rogers’ Diffusion of …


Quality Improvement Project, Communicating With The Dying Patient: A Simulation Experience For Nursing Students, Jason Weger Dec 2025

Quality Improvement Project, Communicating With The Dying Patient: A Simulation Experience For Nursing Students, Jason Weger

Doctor of Nursing Practice Projects

Effective communication with patients near the end of life is a crucial yet often underdeveloped skill among nursing students. Previous research highlights a persistent gap in training for end-of-life communication in nursing schools. This quality improvement project implemented a simulation-based educational intervention to improve end-of-life communication skills among first-semester nursing students at a community college in Oklahoma. A needs assessment identified significant gaps in students' readiness for emotionally charged patient interactions. Guided by Prosci’s Change Model and Jeffries Simulation Theory, the project used a faculty-led simulation experience to teach evidence-based communication strategies, including appropriate word choice, therapeutic presence, and active …


Quality Improvement Project: Reducing Hospitalizations In The Long-Term Care Setting, Nenna Nzeocha Dec 2025

Quality Improvement Project: Reducing Hospitalizations In The Long-Term Care Setting, Nenna Nzeocha

Doctor of Nursing Practice Projects

Hospitalizations in the long-term care setting can lead to higher costs incurred by skilled nursing home residents and a poorer quality of life. This quality improvement (QI) project evaluated whether an educational intervention on the Reducing Avoidable Facility Transfers (RAFT) model impacted hospitalization rates in the skilled nursing facility (SNF), while also assessing the confidence level of facility staff on the intervention. The project utilized Lewin’s change theory and the Donabedian model framework and was aimed at developing interventions that impact hospitalizations in the SNF using the RAFT model. A quasi-experimental design was used and consisted of a pre-and-post implementation …