Biomolecular Crystals As Functional Materials,
2024
CUNY Graduate Center
Biomolecular Crystals As Functional Materials, Fahmeed Khan Sheehan
Dissertations, Theses, and Capstone Projects
The field of supramolecular chemistry has undergone significant evolution over the last few decades, progressing from fundamental studies of self-assembling systems to the rational design of functional materials with exceptional properties. Among these materials, short peptides have emerged as a chemically simple yet highly versatile class of biomimetic compounds. Initially, short peptides were used as model systems to understand larger protein interactions. As the field progressed, short peptides were found to have exceptional functionality, and are now explored as functional nanomaterials for diverse applications. In many cases, short peptide materials have displayed properties not found in biology, in some cases …
Nanoparticles For Applications In Specific Diagnostics And Precision Medicine,
2024
CUNY Graduate Center
Nanoparticles For Applications In Specific Diagnostics And Precision Medicine, Naxhije Berisha
Dissertations, Theses, and Capstone Projects
Heterogeneity is common in the expression of cancer and treatment response. Precision medicine enables healthcare providers to tailor medical care to an individual's distinct genetic and environmental makeup. This customization has the potential to result in more efficient treatments while minimizing side effects. We believe that by studying the interface of nanotechnology and cancer medicine we can elucidate innovative solutions that address the challenges of disease heterogeneity. This includes advancements in drug delivery, formulations development, and diagnostic sensing. We highlight three studies that use nanotechnology for applications in precision medicine. In Chapter 2, we highlight design optimization of drug formulations …
Towards A Fundamental Understanding Of The Polymer Cold Spray Process,
2024
Rowan University
Towards A Fundamental Understanding Of The Polymer Cold Spray Process, Tristan Bacha
Theses and Dissertations
Cold spray technology lends itself as a versatile process to rapidly apply quality polymer coatings to various substrates; barring limited, although clearly demonstrated, success. The limited success of polymer sprays is a result of modern cold spray knowledge originating from studies with metals. Thus, a deeper understanding of how polymers behave in cold spray is needed to make polymer cold spray a commercially viable process. Various tools are used in this dissertation to progress the fundamental understanding of polymer cold spray as it relates to general processing parameters with a focus on characteristics that do not occur in metals. Polymer …
Biodiesel Transesterification Of Spent Coffee Grounds Using Dbu As A Catalyst: Using Dbu To Make Biodiesel From Coffee Grounds,
2024
Purdue University
Biodiesel Transesterification Of Spent Coffee Grounds Using Dbu As A Catalyst: Using Dbu To Make Biodiesel From Coffee Grounds, Christopher Stepherson, Pericles Karras, Amy Ha, Phuc Tan Nguyen, Abigail Pati, Jacob Hejazi, Soheil Hussain, Elizabeth De Young, Shuaicheng Fu
The Journal of Purdue Undergraduate Research
Coffee is one of the most universally consumed beverages. The world produces 60 million tons of spent coffee grounds (SCGs) as waste per year. Biodiesel made from SCGs is an eco-friendly alternative fuel but proves difficult to produce. 1,8-Diazabicyclo[ 5.4.0]undec-7- ene (DBU) was used as both a solvent and a catalyst with methanol to determine the efficiency of biodiesel production from SCGs. The process was completed by extracting coffee oil from acid-washed spent coffee grounds (AWSCGs) using hexane. The two extraction methods that were explored were Soxhlet and agitation. DBU is an interesting choice as a solvent and a catalyst …
Rational Design Of Heterostructured Nanomaterials For Accelerating Electrocatalytic Hydrogen Evolution Reaction Kinetics In Alkaline Media,
2024
Shanghai Key Laboratory for R&D and Application of Metallic Functional Materials, Institute of New Energy for Vehicles, School of Materials Science and Engineering, Tongji University, Shanghai 201804, China
Rational Design Of Heterostructured Nanomaterials For Accelerating Electrocatalytic Hydrogen Evolution Reaction Kinetics In Alkaline Media, Hai-Bin Ma, Xiao-Yan Zhou, Jia-Yi Li, Hong-Fei Cheng, Ji-Wei Ma
Journal of Electrochemistry
Owing to the merits of high energy density, as well as clean and sustainable properties, hydrogen has been deemed to be a prominent alternative energy to traditional fossil fuels. Electrocatalytic hydrogen evolution reaction (HER) has been considered to be mostly promising for achieving green hydrogen production, and has been widely studied in acidic and alkaline solutions. In particular, HER in alkaline media has high potential to achieve large-scale hydrogen production because of the increased durability of electrode materials. However, for the currently most prominent catalyst Pt, its HER kinetics in an alkaline solution is generally 2–3 orders lower than that …
Monodispersed Cu-Tcpp/Cu2O Hybrid Microspheres: A Superior Cascade Electrocatalyst Toward Co2 Reduction To C2 Products,
2024
New Energy Research Institute, School of Environment and Energy, South China University of Technology, Higher Education Mega Center, Guangzhou 510006, Guangdong, China
Monodispersed Cu-Tcpp/Cu2O Hybrid Microspheres: A Superior Cascade Electrocatalyst Toward Co2 Reduction To C2 Products, Zi-Xuan Wan, Aidar Kuchkaev, Dmitry Yakhvarov, Xiong-Wu Kang
Journal of Electrochemistry
The electrochemical conversion of carbon dioxide (CO2) into valuable chemicals is a feasible way to mitigate the negative impacts of overmuch CO2 emissions. Porphyrin-based metal organic frameworks (MOFs) are expected to be used for selective and efficient electrochemical CO2 reduction (ECR) with porous structure and ordered active sites. Herein, we report the synthesis of a monodispersed and spherical organic/inorganic hybrid Cu-TCPP@Cu2O electrocatalyst composed of Cu-TCPP (TCPP=tetrakis (4-carboxyphenyl) porphyrin) and Cu2O, where TCPP plays significant roles in regulating the morphology. In-situ formed Cu during ECR process in combination with Cu-TCPP (Cu-TCPP@Cu) can suppress …
Virtual Test Beds For Image-Based Control Simulations Using Blender,
2024
Department of Chemical Engineering and Materials Science, Wayne State University
Virtual Test Beds For Image-Based Control Simulations Using Blender, Akkarakaran Francis Leonard, Govanni Gjonaj, Minhazur Rahman, Helen E. Durand
Chemical Engineering and Materials Science Faculty Research Publications
Process systems engineering research often utilizes virtual testbeds consisting of physics- based process models. As machine learning and image processing become more relevant sensing frameworks for control, it becomes important to address how process systems engineers can research the development of control and analysis frameworks that utilize images of physical processes. One method for achieving this is to develop experimental systems; another is to use software that integrates the visualization of systems, as well as modeling of the physics, such as three-dimensional graphics software. The prior work in our group analyzed image-based control for the small-scale example of level in …
Development Of A New Approach Using An Artificial Neural Network For Estimating Oil Formation Volume Factor At Bubble Point Pressure Of Egyptian Crude Oil,
2024
The British University in Egypt
Development Of A New Approach Using An Artificial Neural Network For Estimating Oil Formation Volume Factor At Bubble Point Pressure Of Egyptian Crude Oil, Attia Attia, Abdelrahman Gouda Eng.
Petroleum Engineering and Gas
Understanding the phase behavior and volumetric changes of reservoir fluids throughout the extent of reservoir lifetime are crucially required for effective-commercial oil recoveries. Ideally, reservoir fluid properties are experimentally measured by laboratory experiments known as PVT tests nonetheless, these tests are prohibitive, time-consuming, and required to restrict sampling and transporting procedures. For these discernible reasons, several modeling approaches have been developed. By reviewing the literature, one crucial obstacle that encounters field applicability of most extant models is the selection of input variables. Moreover, a great percentage of extant models employ the results of lengthy experimental tests such as differential gas …
Development Of Tio2/Nh2-Mil-125 Nanocomposite For The Removal Of Ciprofloxacin Under Induced Solar Irradiation,
2024
United Arab Emirates University
Development Of Tio2/Nh2-Mil-125 Nanocomposite For The Removal Of Ciprofloxacin Under Induced Solar Irradiation, Bilkis Mojisola Ajiwokewu
Thesis/ Dissertation Defenses
This research focuses on the development and application of Metal-Organic Frameworks (MOFs)-based nanocomposites for the photocatalytic removal of pharmaceutical contaminants, with a specific emphasis on ciprofloxacin (CIP). The photocatalytic degradation of CIP was investigated using as-synthesized photocatalysts of TiO2 nanowires (TiO2NWs), bare MOF of NH2-MIL-125, TiO2NW/NH2-MIL-125 composite, and Lanthanum (La)-doped composite. Intriguingly, the TiO2NW/NH2-MIL-125 composite exhibited the highest efficiency, achieving a photodegradation rate of 0.0111 min-1, surpassing the independent performances of bare MOF of NH2-MIL-125 and TiO2NW. The observed efficiency was attributed to the formation of a Z-scheme heterojunction …
Exploring The Electrochemical Performance Of Calcium-Ion Batteries With Novel Cathodes And Electrolytes,
2024
Syracuse University
Exploring The Electrochemical Performance Of Calcium-Ion Batteries With Novel Cathodes And Electrolytes, Paul Alexis Chando
Dissertations - ALL
The development of electric vehicles and energy storage devices are part of larger international efforts to create a sustainable future. Lithium-ion batteries have become crucial components to powering these technologies. However, the growing dependence of this singular battery chemistry to power an ever expanding landscape of technologies raises sustainability issues around lithium. Exploration of alternate battery chemistries have become part of research efforts to meet global energy demands. Calcium has emerged as one such battery system that could help alleviate stresses placed on lithium with its energy density and cost. Battery chemistries are unique, and each battery possesses its own …
Characterizing Nonlinear Fluid Flow In 3d Printed Rock Fractures: Effects Of Roughness, Aperture, And Intersection Angles,
2024
University of North Dakota
Characterizing Nonlinear Fluid Flow In 3d Printed Rock Fractures: Effects Of Roughness, Aperture, And Intersection Angles, Ghoulem Ifrene, Prasad Pothana, Sven Egenhoff, Nicholas Bittner, Kuldeep Singh
Petroleum Engineering Posters and Presentations
Understanding fluid flow behavior at fracture intersections is vital to geothermal energy extraction, underground water flow, and CO2 storage. Here, laboratory experiments were performed to study the effect of surface roughness, intersection angles, and aperture on nonlinear flow behavior in simple fracture networks. A FormLabs (3B+) 3D printer was used to fabricate 8 samples of 38.1mm in diameter and 59.43mm or 54.9mm in length with 2 intersecting fractures of 10o and 40o respectively. The surface roughness of the fractures was based on laser profilometry measurements from two induced mode 1 rock fractures, with a joint roughness coefficient …
Reactive Capture And Conversion Of Co2 Into Hydrogen Over Bifunctional Structured Ce1-Xcoxnio3/Ca Perovskite-Type Oxide Monoliths,
2024
Missouri University of Science and Technology
Reactive Capture And Conversion Of Co2 Into Hydrogen Over Bifunctional Structured Ce1-Xcoxnio3/Ca Perovskite-Type Oxide Monoliths, Khaled Baamran, Shane Lawson, Ali A. Rownaghi, Fateme Rezaei
Chemical and Biochemical Engineering Faculty Research & Creative Works
Carbon capture, utilization, and storage (CCUS) technologies are pivotal for transitioning to a net-zero economy by 2050. In particular, conversion of captured CO2 to marketable chemicals and fuels appears to be a sustainable approach to not only curb greenhouse emissions but also transform wastes like CO2 into useful products through storage of renewable energy in chemical bonds. Bifunctional materials (BFMs) composed of adsorbents and catalysts have shown promise in reactive capture and conversion of CO2 at high temperatures. In this study, we extend the application of 3D printing technology to formulate a novel set of BFMs composed …
Efficient Discovery And Industrialized Manufacture Of Terpenoids,
2024
School of Pharmaceutical Sciences, Wuhan University, Wuhan 430072, China
Efficient Discovery And Industrialized Manufacture Of Terpenoids, Haoming Chi, Liying Er, Tiangang Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Terpenoids, a class of chemical entities with diverse biological activities in nature, demonstrate significant potential for applications in fields such as drug discovery, flavor industry, and agriculture. However, traditional methods face challenges, including inefficiency and high costs, in the discovery and industrialization of terpenoids. The rapid development of synthetic biology, genomics, artificial intelligence, and automation provides new opportunities for efficient terpenoid discovery and industrialization. This study comprehensively analyzes how these technologies synergistically contribute to the discovery, optimization, and large-scale production of terpenoids, and summarizes the current high-yield situations of terpenoids. The aim is to propose innovative strategies to accelerate technological …
Retraction Notice To “High Density Conductive Lifepo4 Cathode With Enhanced High-Rate And High Temperature Performance” [Mater. Chem. Phys. 232 (2019) 367–373, (S0254058419304110), (10.1016/J.Matchemphys.2019.05.014)],
2024
Missouri University of Science and Technology
Retraction Notice To “High Density Conductive Lifepo4 Cathode With Enhanced High-Rate And High Temperature Performance” [Mater. Chem. Phys. 232 (2019) 367–373, (S0254058419304110), (10.1016/J.Matchemphys.2019.05.014)], David Seung-Hyun Lee, Won Bin Im, Xinhua Liang
Chemical and Biochemical Engineering Faculty Research & Creative Works
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. The Editor-in-Chief found that the corresponding author of this article submitted the manuscript to the journal without the consent of the two individuals named as "co-authors", using invented email addresses to impersonate them. In addition, based on the raw materials presented to the journal by the second co-author and the Editor-in-Chief's own investigation, the Editor-in-Chief believes that some results in the paper are fabricated. Based on these two findings, the Editor-in-Chief has decided to retract the …
Physicochemical Characterization Of Metal Organic Framework Materials: A Mini Review,
2024
Edith Cowan University
Physicochemical Characterization Of Metal Organic Framework Materials: A Mini Review, Hussein R. Abid, Muhammad R. Azhar, Stefan Iglauer, Zana H. Rada, Ahmed Al-Yaseri, Alireza Keshavarz
Research outputs 2022 to 2026
Metal-organic frameworks (MOFs) are promising materials offering exceptional performance across a myriad of applications, attributable to their remarkable physicochemical properties such as regular porosity, crystalline structure, and tailored functional groups. Despite their potential, there is a lack of dedicated reviews that focus on key physicochemical characterizations of MOFs for the beginners and new researchers in the field. This review is written based on our expertise in the synthesis and characterization of MOFs, specifically to provide a right direction for the researcher who is a beginner in this area. In this way, experimental errors can be reduced, and wastage of time …
Scaffold-Based 3d Cell Culture Models In Cancer Research,
2024
American University of Sharjah
Scaffold-Based 3d Cell Culture Models In Cancer Research, Waad H. Abuwatfa, William G. Pitt, Ghaleb A. Husseini
Faculty Publications
Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional two-dimensional (2D) cell culture systems. In 3D cell cultures, cancer cells are grown in an environment that more closely mimics the 3D architecture and complexity of in vivo tumors. This approach has revolutionized cancer research by providing a more accurate representation of the tumor microenvironment (TME) and enabling the study of tumor behavior and response to therapies in a more physiologically relevant context. One of the key benefits of 3D cell culture in cancer research is the ability to recapitulate the complex interactions …
Model Predictive Control Of A Lab-Scale Thermal Energy Storage System In Relap5-3d,
2024
Brigham Young University - Provo
Model Predictive Control Of A Lab-Scale Thermal Energy Storage System In Relap5-3d, Jaron Wallace, Daniel Hill, David Thurston, John Hedengren, Matthew Memmott
Faculty Publications
Increased renewable energy penetration of an electrical grid generally creates more supply fluctuations. Traditional base-load systems, such as nuclear power, can be retrofitted with thermal energy storage (TES) systems to meet supply demand fluctuations. These systems can store energy during low electricity demand times to allow the reactor to operate at constant power while simultaneously fluctuating electricity output. The control of these systems is of vital importance and Model Predictive Control (MPC) is a leading control mechanism for optimized production plans with forecast information. This study combines high fidelity RELAP5-3D models with MPC to control an experimental benchtop system that …
Grand Challenges In Membrane Transport, Modeling And Simulation,
2024
University of Arkansas, Fayetteville
Grand Challenges In Membrane Transport, Modeling And Simulation, Jacob Monroe, Chidambaram Thamariselvan, Ranil Wickramasinghe
Chemical Engineering Faculty Publications and Presentations
Today, membranes play an increasing role in separation processes across a wide range of industries, including water treatment, biomedical applications, bioseparations, and gas separations (Yeom et al., 2022). Numerous different membrane types exist, which can be broadly categorized as either porous or non-porous, where pores may be or may not be filled with a separate phase from the bulk solvent and membrane phases. In addition, various driving forces exist - pressure, concentration, electric field, etc.—that lead to transport across the membrane. For a porous membrane, solute transport is usually governed by convective flow through the pores. Micron-sized pores are used …
Cancer Treatment By Targeting Hdac4 Translocation Induced By Microsecond Pulsed Electric Field Exposure: Mechanistic Insights Through Kinases And Phosphatases,
2024
Rowan University
Cancer Treatment By Targeting Hdac4 Translocation Induced By Microsecond Pulsed Electric Field Exposure: Mechanistic Insights Through Kinases And Phosphatases, Zahra Safaei
Theses and Dissertations
Epigenetic modifications, arising from sub-cellular shifts in histone deacetylase (HDAC) activity and localization, present promising strategies for diverse cancer treatments. HDACs, enzymes responsible for post-translational histone modifications, induce these epigenetic changes by removing acetyl groups from ε-N-acetyl-lysine residues on histones, thereby suppressing gene transcription. Within the HDAC group, class IIa HDACs are notable for their responsiveness to extracellular signals, bridging the gap between external stimuli, plasma membrane, and genome through nuclear-cytoplasmic translocation. This localization offers two significant mechanisms for cancer treatment: nuclear accumulation of HDACs represses oncogenic transcription factors, such as myocyte-specific enhancer factor 2C (MEF2C), triggering various cell death …
Development Of A Xenograft For Annular Repair Using Pulsed Electric Field Exposures For Enhanced Decellularization,
2024
Rowan University
Development Of A Xenograft For Annular Repair Using Pulsed Electric Field Exposures For Enhanced Decellularization, Prince Mensah Kwaku Atsu
Theses and Dissertations
Severe back injuries and chronic pain necessitate surgical replacement of damaged intervertebral disc (IVD) cartilage in advanced disease stages. Bovine IVD tissue has been exposed to an upper threshold pulsed electric field (PEF) dose, causing cell death without thermal damage to the tissue. Subsequent PEF exposures at lower magnitudes have accelerated the removal of immunogenic biomolecules though electrokinetic extraction using optimized aqueous solutions. This approach yields a natural scaffold, ready for biocompatibility and mechanical strength assessment. The effects of microsecond pulsed electric fields (µsPEF) on primary bovine AF fibroblast-like cells have been characterized in vitro. PEFs of 10 and 100 …
