Biomedical Engineering and Bioengineering Commons^™

An Evaluation Of Total Navicular Implants: A Scoping Review, James Mcclure Hughes, Nicholas Belardo Obias, Amanda Killeen

School of Podiatric Medicine - Student Research

The aim of this study is to determine the efficacy and safety profile of total navicular implants based on current literature.

Navicular insults such as high-energy trauma, osteonecrosis, and Muller-Weiss syndrome may result in avascular necrosis or a critical sized bone defect, conditions that are highly difficult to manage given current treatment modalities. Total navicular implants may offer a solution to these problems. While 3D printing of implants remains investigational, its use in highly individualized cases involving the talus has had promising results with conditions like avascular necrosis, tumors, trauma, and arthritis. The navicular is unique in its attachments to …

Vitasense: Noninvasive Physiological Signal Measurement From Video Data, Ava Dorow, Justin Mcparland, Ashley Schindler

Biomedical Engineering and Sciences Student Publications

• Heart rate monitoring enables proactive patient care
• Imaging Photoplethysmography (iPPG) enables noncontact measurement 
• Improves access to remote and virtual care

Biopulse: Split Hopkinson (Kolsky) Bar, Andrew Carr, Sebastian Deniz, Rachel Hizon, Stefan Paton

Biomedical Engineering and Sciences Student Publications

A Split Hopkinson (Kolsky) Bar is a device used to find a material’s mechanical response under high strain rate loading scenarios (10² – 10⁴ s⁻¹) [1]. It is commonly used to simulate vehicle crashes or ballistic impacts. The novelty of the device is its size and cost of its components compared to other SPHBs on the market. The motivation is to further the capabilities on campus by providing the first dynamic material testing device.

Biostress: An Engineered Platform For Detecting Cellular Damage Upon Mechanical Impact, Lindsay Avila, Nina Fiordaliso, Mai Tran

Biomedical Engineering and Sciences Student Publications

Mechanical impact stimuli are commonly associated with cellular damage and lower cell survival rates. However, mild impacts can promote responses that are adaptive. The heat shock protein 70 (HSP70) is a stressinducible protein that serves as an early biomarker for cellular stress. The relationship between impact severity and cellular response remains unclear.

Clear Aligner Overcorrection To Reduce Incisor Tipping | In Vitro, Benjamin Losch, Eddie Wawrzycki-Stein, Kylie Stong, Niko Burger

Biomedical Engineering and Sciences Student Publications

Quantify the biomechanical effects of overcorrection angles on tipping angle and periodontal moment during incisior retractions using both in vitro experiments and finite element analysis (FEA).

C-Side: Concussion Sideline Injury Detection And Evaluation, Emily Acampora, Emma Angelo, Kyle Burden

Biomedical Engineering and Sciences Student Publications

Concussion are a form of mild traumatic brain injury (mTBI), affecting an estimated 3.8 million Americans anually. Athletes are particularly susceptible to incurring concussions. Current diagnostic methods are timeconsuming and rely primarily on subjective measures.

Cardio Clarity -Wearable Cardiac Monitoring, Kaitlyn Dunn, Matthew Kotze, Emily Matheson, Caroline Moore

Biomedical Engineering and Sciences Student Publications

Purpose: Develop a low-cost wearable system for an accessible cardiac monitoring platform

Cardiosync: Real-Time Pid Control Of Lvad Hemodynamics, Brendan Bouchard, Morgan Brenner, Panagiotis Vasileiadis, Michaela Wittman

Biomedical Engineering and Sciences Student Publications

Goals:

Develop a real-time, closed-loop control system for autonomous LVAD RPM adjustment. Minimize clinician reliance, reducing hospital visits and healthcare costs. Improve patient independence and quality of life. Maintain stable hemodynamic performance and reduce complications. Reduce patient mortality

Ocusensus: Real-Time Force Detection Strabismus Hook, Asa Barnhart, Niko Burger, Patricia Carrelo-Creque, Kristie Fonseca

Biomedical Engineering and Sciences Student Publications

Strabismus affects approximately 2–5% of the general population [1]. Primary treatment is (strabismus) surgery but current methods result in approximately 36% of patients undergoing reoperation within 5 years [2]. One factor proposed to contribute towards reoperation is insufficient force applied to extraocular muscles during surgery. Excessive force triggers the oculocardiac reflex (OCR) which lowers heart rate by >20%[3]

Plant Growth Promoting Phenotypes Of Fungal Isolates From The International Space Station, Shane Doyle, Frances A. Edmonson

Ocean Engineering and Marine Sciences Student Publications

• In situ (on site) space crop production is vital for sustainability and dietary health of astronauts. 
• We hypothesize that International Space Station (ISS) derived fungal isolates will stimulate plant growth and express PGP phenotypes.
• Eleven space-viable fungi were screened via phenotypic testing to identify plant growthpromoting (PGP) activity.
• Prior research has been conducted solely with ISS derived bacteria, while ISS fungi are unexplored, which could reveal new or improved symbiotic relationships and growth factors.

A Treatise On Tool Development: The Arthroscope’S Cultural, Technological, And Metascientific Translation, Montgomery F. Waterer

Honors Theses

The arthroscope was a revolutionary development in the fields of medicine, engineering, and ethics. There are many valuable lessons to be learned from the story of its development and translation that are relevant to the future of medicine and society. Beginning with a brief description of the tool’s design, this paper will examine a period within the history of the arthroscope. This window contains multiple innovators and ends with the life and work of Dr. Robert Jackson. In examining the relevant historical facts of its development, this paper will then briefly address the importance of sports medicine in the development …

Erk Builds A Population Of Short-Lived Nascent Adhesions That Produce Persistent Edge Protrusion And Cell Migration, Andrew P. Shepherd, Keith R. Carney, Majid Rostami, Jakaria Shawon, Andrew Elliott, Shiela C. Samson, Sangyoon J. Han, Michelle C. Mendoza

Michigan Tech Publications

Cell migration is realized through the fast and persistent protrusion of a leading edge in the direction of movement. The actin and adhesion structures that build edge protrusions are integrated such that pro-migration signaling pathways must control both assemblies to induce protrusion. Understanding the contribution of adhesion regulation has been complicated by the inability to selectively assay the nascent adhesions that promote edge protrusion. Here, we dissect how the core RAS → RAF → MEK → ERK pathway’s control of nascent adhesions contributes to edge protrusion and cell migration by targeting an ERK FRET biosensor to adhesions and quantifying ERK’s …

Opportunistic Breast Cancer Detection With Photon-Counting Ct: A Quantitative Pilot Study Of Reconstruction-Dependent Image Quality, Graham Hannon

McKelvey School of Engineering Graduate Student Theses & Dissertations

Photon-counting computed tomography (PCCT) has emerged as a promising imaging modality with improved spatial resolution and contrast capabilities compared to conventional energy-integrating detector systems. These advantages present an opportunity for opportunistic detection of breast cancer in routine thoracic CT scans that include breast tissue. In this pilot study, we evaluated the feasibility of opportunistic breast cancer detection using clinical PCCT data through quantitative image analysis. Two patients with confirmed breast malignancies and corresponding thoracic PCCT scans were retrospectively analyzed. Dedicated reconstructions were performed with varying convolution kernels, field-of-view sizes, and virtual monoenergetic spectra. Image quality was assessed using signal-to-noise ratio …

Spatial Computing With The Apple Vision Pro In Minimally Invasive Procedure Simulation: A Randomized Crossover Feasibility Study, Sydney Cooper, Aaron Kyle Jones, Rahul Anil Sheth, Koustav Pal, Bruno Odisio, Mark Blaylock, Shelita Kimble, Justin Bird, David Rice, Daniel Shoenthal, Emil Patel, Vipin Kamath, Sanjay Gupta, Jeffrey Siewerdsen, Joshua Kuban

Advances in Cancer Education and Quality Improvement

Purpose: This study aimed to evaluate the feasibility of wearing the Apple Vision Pro (AVP), a mixed-reality headset that integrates augmented and virtual reality, while performing minimally invasive procedures. While studies have demonstrated that spatial computing technology can improve surgical precision and reduce the risks of surgical complications, to our knowledge, no studies have specifically addressed the impact of the AVP on task performance during simulated image-guided procedures.

Materials and Methods: Thirteen diagnostic and interventional radiology residents performed image-guided central venous catheter placement, thoracentesis, and paracentesis on simulation models. Each participant completed a non-timed practice followed by the procedures once …

Uptake And Fate Of Silver And Zinc Engineered Nanoparticles In Maize Under Single And Binary Dosing Soil Ecosystems, Lei Xu, Qingbo Yang, Xingmao Ma, Honglan Shi, John Yang, Hu Yang, Samira Mahdi, Ying Wang, Young Shin Jun

Chemistry Faculty Research & Creative Works

Recent agricultural applications of engineered metallic nanoparticles (ENPs) have raised concerns about their uptake and fate in plants. To understand this critical issue, this study investigated the fate and uptake of silver (Ag) and zinc oxide (ZnO) ENPs in maize (Zea mays L.) after single or binary ENP exposure in soil. Results indicated that both Zn and Ag elemental concentrations in roots increased with increasing ENP dosage. Ag NPs in the tissues were detected, but not Zn NPs. Ag NP concentration was 3 times higher in the roots than in the shoots at low Ag NP dosing, while Ag NP …

Robust Non-Invasive Cardiac Index Prediction Via Feature Integration And Data-Augmented Neural Networks, Chih-Hao Chang, Mei-Ling Chan, Yu-Hung Fang, Po-Lin Huang, Tsung-Yi Chen, Tsun-Kuang Chi, I Elizabeth Cha, Tzong-Rong Ger, Kuo-Chen Li, Shih-Lun Chen, Liang-Hung Wang, Jia-Ching Wang, Patricia Angela R. Abu

Department of Information Systems & Computer Science Faculty Publications

Concurrent with the rising consumption of ultra-processed, high-calorie diets and the decline in physical activity, obesity and related cardiovascular conditions among young adults have continued to increase, becoming an important global public health concern. This study integrates non-invasive Internet of Things (IoT) sensing devices, including the TERUMO ES-P2000 blood pressure monitor (Terumo Corp., Tokyo, Japan) and the PhysioFlow PF07 Enduro cardiac hemodynamic analyzer (Manatec Biomedical, Poissy, France), with an artificial neural network (ANN) for cardiac index (CI) prediction. Through appropriate data preprocessing and model training strategies, the generalization ability and stability of the proposed CI prediction model were significantly enhanced. …

Implantable, Sensor-Embedded Vascular Graft Towards Wireless Monitoring Of Stenosis, Nnamdi Dike

LSU Master's Theses

Arteriovenous (AV) grafts are commonly used to provide vascular access for hemodialysis in patients with end-stage renal disease. Despite their widespread use, AV grafts are prone to complications such as stenosis and thrombosis. Early detection of these conditions remains challenging with current monitoring methods too costly or insufficient. This work presents the design, fabrication, and validation of an LC pressure sensor embedded within a model AV graft to enable real-time monitoring. The proposed system integrates a parallel-plate capacitive pressure sensor with a spiral inductor to form an LC circuit embedded within an elastomeric graft wall. The Ecoflex 00-30 dielectric layer …

Mathematical Modelling And Optimisation Of The Reactor For The Esterification Process Of Safflower Oil With N-Butyl Alcohol, Sadritdin Makhamatdinovich Turabdjanov Academician, Hasan Sadriddin Ugli Fozilov, Ozoda Bakhronovna Axmedova, Sadriddin Fayzullayevich Fozilov

Technical science and innovation

This study addresses the mathematical modelling and optimisation of a reactor for the esterification of safflower oil with n-butyl alcohol. To improve process controllability and reduce the need for numerous pilot-scale trials, an ideal-mixing continuous stirred-tank reactor (CSTR) model was adopted. Incorporating reaction kinetics, the effect of contact time on the relative viscosity of the product mixture was analysed. The modelling results indicate that achieving an acceptable degree of feedstock conversion is difficult when a single ideal-mixing reactor is used. Therefore, a CSTR cascade was proposed, and the configuration with N = 2 reactors was selected as the most appropriate …

Theoretical And Practical Foundations Of Healthcare System Digitalization, Sanjarbek Bekturdiev Sharifboyevich Phd, Muxlisa G‘Ulom Qizi G‘Ofurova

Technical science and innovation

The digital transformation of healthcare represents a key direction in improving the accessibility, quality, and efficiency of medical services. This study examines the main components of eHealth, including telemedicine, electronic health records, cloud technologies, and mobile applications, as well as the role of international organizations in promoting national digital health strategies. Particular attention is given to the current state of digital healthcare in the Republic of Uzbekistan, where significant progress has been made in developing infrastructure and implementing information systems, although challenges related to integration, standardization, and regulatory support remain. The work identifies the main trends in the development of …

Development Of New Methods For Calculating Pressure And Energy Losses For Pumping Station Water Intakes, Faxriddin Jaylovovich Nosirov, Oleg Yakovlevich Glovatsky, Jurabek Abdyrahmon O'G'Li Urolov, Abduqodirkhon Samatkhonovich Abdullakhaev, Anvar Mamur Ugli Uzokov

Technical science and innovation

The aim of this study is to improve the efficiency of water resource management methods. Improvements to the water intake of the Karshi Main Canal are considered using calculations of pressure losses at the entry and exit of liquid into the flow, which differ from pressure losses in a stationary medium. The article considers some of the methods for using renewable energy sources, where the change in gravitational potential energy does not depend on the way of using energy and the operating scheme is a gravitational energy pump. The implementation of control and monitoring systems is necessary to ensure optimal …