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Ischemic Preconditioning Does Not Improve Time Trial Performance In Recreational Runners, Alexander HK Montoye, Clara J. Mitchinson, Olivia R. Townsend, Conner H. Nemmers, Caroline N. Serkaian, Brian C. Rider 2020 Alma College

Ischemic Preconditioning Does Not Improve Time Trial Performance In Recreational Runners, Alexander Hk Montoye, Clara J. Mitchinson, Olivia R. Townsend, Conner H. Nemmers, Caroline N. Serkaian, Brian C. Rider

International Journal of Exercise Science

International Journal of Exercise Science 13(6): 1402-1417, 2020. Some evidence indicates that ischemic preconditioning (IPC) may positively affect endurance exercise performance, but IPC’s effect on running performance is unclear. This study’s purpose was to examine the effect of IPC on running performance in recreational runners. Participants (n=12) completed IPC, a sham (SH) condition, and a leg elevation without blood restriction (LE) control condition on separate days (order randomized). For IPC, blood was restricted using blood pressure cuffs inflated to 220 mmHg at the thigh. For SH, the cuffs were inflated to only 20 mmHg. For LE ...


Validity And Reliability Of The Vo2 Master Pro For Oxygen Consumption And Ventilation Assessment, Alexander HK Montoye, Joseph D. Vondrasek, James B. Hancock II 2020 Alma College

Validity And Reliability Of The Vo2 Master Pro For Oxygen Consumption And Ventilation Assessment, Alexander Hk Montoye, Joseph D. Vondrasek, James B. Hancock Ii

International Journal of Exercise Science

International Journal of Exercise Science 13(4): 1382-1401, 2020. This study assessed validity and reliability of the VO2 Master Pro portable metabolic analyzer for assessment of oxygen consumption (VO2) and minute ventilation (VE). In Protocol 1, eight male participants (height: 182.6 ± 5.8 cm, weight: 79.6 ± 8.3 kg, age: 41.0 ± 12.3 years) with previous competitive cycling experience completed an hour-long stationary cycling protocol twice, progressing from 100-300 Watts every 10 minutes while wearing the VO2 Master and a criterion measure (Parvomedics) for five minutes each, at each stage. In Protocol 2, 16 ...


Evaluation Of Muscle Damage, Body Temperature, Peak Torque And Fatigue Index In Three Different Methods Of Strength Gain, Nathalie de Almeida Barros, Felipe J. Aidar, Dihogo de Matos Professor, Raphael Fabrício de Souza, Eduardo Borba Neves, Breno Guilherme de Araujo Tinoco Cabral, Enilton Aparecido Camargo, Victor Machado Reis 2020 McGill University, Montreal

Evaluation Of Muscle Damage, Body Temperature, Peak Torque And Fatigue Index In Three Different Methods Of Strength Gain, Nathalie De Almeida Barros, Felipe J. Aidar, Dihogo De Matos Professor, Raphael Fabrício De Souza, Eduardo Borba Neves, Breno Guilherme De Araujo Tinoco Cabral, Enilton Aparecido Camargo, Victor Machado Reis

International Journal of Exercise Science

International Journal of Exercise Science 13(3): 1352-1365, 2020. The aim of this study was to evaluate and compare three different strength training protocols for the lower limbs by using biochemical indicators of muscle damage, thermographic analysis, and neuromuscular performance. In total, 10 men (age: 22.50 ± 2.84 years; weight, 75.45 ± 6.86 kg) completed the study. All the athletes were subjected to three methods of resistance training (RT): traditional, tension, and occlusion training. Serum concentrations of creatine kinase, lactate dehydrogenase, aspartate aminotransferase, and alanine aminotransferase were used as indicators of muscle damage. To measure muscle strength, the ...


Cross-Validation Of Ratings Of Perceived Exertion Derived From Heart Rate Target Ranges Recommended For Pregnant Women, Danilo F. da Silva, Shuhiba Mohammad, Kelly Ann Hutchinson, Kristi B. Adamo 2020 University of Ottawa

Cross-Validation Of Ratings Of Perceived Exertion Derived From Heart Rate Target Ranges Recommended For Pregnant Women, Danilo F. Da Silva, Shuhiba Mohammad, Kelly Ann Hutchinson, Kristi B. Adamo

International Journal of Exercise Science

International Journal of Exercise Science 13(3): 1340-1351, 2020. Currently, there are no established evidence-based rating of perceived exertion (RPE) targets for physical activity (PA) in pregnant women. Yet, a set of target heart rate (HR) ranges have been recommended. Using the Borg Scale, we aimed to determine and validate the RPE target ranges for different PA intensities derived from the recommended HR ranges in the 2019 Canadian Guideline for PA throughout pregnancy. We assessed 13 pregnant women (age: 31.2 ± 3.5 years; gestational age: 20.5 ± 5.0 weeks) using the following three phases: 1) the incremental submaximal ...


High-Protein Diet Associated With Resistance Training Improves Performance And Decreases Adipose Index In Rats, Paula Caroline de Almeida, Thiago da Rosa Lima, Eudes Thiago Pereira Avila, Geovane José Tolazzi, Letícia Pereira Cavalcante, James W. Navalta, Ramires Tibana, Roberto Lopes de Souza, Neuber José Segri, Édila Cristina de Souza, Roberto Carlos Vieira Jr., Fabrício Azevedo Voltarelli 2020 Federal University of Mato Grosso, Cuiabá, Brazil

High-Protein Diet Associated With Resistance Training Improves Performance And Decreases Adipose Index In Rats, Paula Caroline De Almeida, Thiago Da Rosa Lima, Eudes Thiago Pereira Avila, Geovane José Tolazzi, Letícia Pereira Cavalcante, James W. Navalta, Ramires Tibana, Roberto Lopes De Souza, Neuber José Segri, Édila Cristina De Souza, Roberto Carlos Vieira Jr., Fabrício Azevedo Voltarelli

International Journal of Exercise Science

International Journal of Exercise Science 13(2): 1366-1381, 2020. The study tested the hypothesis that a high protein diet based on isolated whey protein (IWP) associated with strength training improves performance and reduces body fat without promoting health damage. Male Wistar rats, 45 days old, were divided into four groups (n = 8 / group): normoprotein sedentary (IWP 14%; NS); hyperprotein sedentary (IWP 35%; HS); normoprotein trained (IWP 14%; NT) and hyperprotein trained (IWP 35%; HT). All groups performed the maximum load test at the beginning and after the vertical ladder training protocol for 6 weeks (3x/week). The performance improved in ...


Efficient Cocaine Degradation By Cocaine Esterase-Loaded Red Blood Cells, Luigia Rossi, Francesca Pierigè, Marco Agostini, Noemi Bigini, Veronica Termopoli, Yingting Cai, Fang Zheng, Chang-Guo Zhan, Donald W. Landry, Mauro Magnani 2020 University of Urbino, Italy

Efficient Cocaine Degradation By Cocaine Esterase-Loaded Red Blood Cells, Luigia Rossi, Francesca Pierigè, Marco Agostini, Noemi Bigini, Veronica Termopoli, Yingting Cai, Fang Zheng, Chang-Guo Zhan, Donald W. Landry, Mauro Magnani

Molecular Modeling and Biopharmaceutical Center Faculty Publications

Recombinant bacterial cocaine esterase (CocE) represents a potential protein therapeutic for cocaine use disorder treatment. Unfortunately, the native enzyme was highly unstable and the corresponding mutagenized derivatives, RBP-8000 and E196-301, although improving in vitro thermo-stability and in vivo half-life, were a partial solution to the problem. For cocaine use disorder treatment, an efficient cocaine-metabolizing enzyme with a longer residence time in circulation would be needed. We investigated in vitro the possibility of developing red blood cells (RBCs) loaded with RBP-8000 and E196-301 as a biocompatible system to metabolize cocaine for a longer period of time. RBP 8000 stability within human ...


Expression And Localization Of The 14-3-3 (Ywha) Protein Family Within Mammals, Neha Kumrah, Santanu De 2020 Nova Southeastern University

Expression And Localization Of The 14-3-3 (Ywha) Protein Family Within Mammals, Neha Kumrah, Santanu De

Mako: NSU Undergraduate Student Journal

The 14-3-3 (YWHA) are a family of homologous, acidic, and highly conserved proteins expressed abundantly and ubiquitously in a wide array of organisms ranging from plants to animals, including humans, which regulate important cellular events. Within mammals, seven isoforms of 14-3-3 exist: β, γ, ε, ζ, η, τ, and σ (stratifin), each of which is encoded by a unique gene. Studies have shown similar expression patterns among mammalian species. The 14-3-3 proteins are commonly expressed and have proven to play critical roles in proper cellular localization, function, and homeostatic regulation. Numerous researchers have investigated the expression and localization patterns of ...


The Acute Effects Of The Covid-19 Pandemic On Physical Activity And Sedentary Behavior In University Students And Employees, Jacob E. Barkley, Andrew Lepp, Ellen Glickman, Gregory S. Farnell, Jake Beiting, Ryan Wiet, Bryan Dowdell 2020 Kent State University

The Acute Effects Of The Covid-19 Pandemic On Physical Activity And Sedentary Behavior In University Students And Employees, Jacob E. Barkley, Andrew Lepp, Ellen Glickman, Gregory S. Farnell, Jake Beiting, Ryan Wiet, Bryan Dowdell

International Journal of Exercise Science

International Journal of Exercise Science 13(5): 1326-1339, 2020. The COVID-19 pandemic has closed non-essential businesses which may alter individuals’ leisure behaviors. Consequently, physical activity and sedentary behavior may be negatively impacted as many fitness and recreational centers have been closed. This study aimed to examine the impact of the pandemic on physical activity and sedentary behavior in a sample of university students and employees before and after the university cancelled face-to-face classes and closed campus. Participants (N = 398) completed the validated Godin physical activity questionnaire and the International Physical Activity Questionnaire which assessed physical activity and sedentary behavior pre- ...


Differences Between Males And Females In Determining Exercise Intensity, Jozelyn Rascon, Elizabeth Trujillo, Francisco J. Morales-Acuna, Alvaro N. Gurovich 2020 The University of Texas at El Paso

Differences Between Males And Females In Determining Exercise Intensity, Jozelyn Rascon, Elizabeth Trujillo, Francisco J. Morales-Acuna, Alvaro N. Gurovich

International Journal of Exercise Science

International Journal of Exercise Science 13(4): 1305-1316, 2020. Even though there are physiological differences between males and females, heart rate (HR), ratings of perceived exertion (RPE), power output (PO), oxygen consumption (VO2), and blood lactate (BL) levels have been used as measures of exercise intensity independently of sex. The purpose of this study was to determine differences between sexes in different exercise intensity models. Thirty (15 females) young, healthy individuals were scheduled for two testing visits 48-72 hours apart. During the first testing visit, a graded exercise test (GXT), with BL obtained at the end of each exercise ...


The Acute Effects Of Antagonist Stretching On Agonist Movement Economy, Justin Shahtout, Shawn Henry, Dylan Ito, Kyle Savellano 2020 Pacific University

The Acute Effects Of Antagonist Stretching On Agonist Movement Economy, Justin Shahtout, Shawn Henry, Dylan Ito, Kyle Savellano

International Journal of Exercise Science

International Journal of Exercise Science 13(4): 1295-1304, 2020. Current research on the effects of stretching on movement performance varies. However, these studies focused on stretching agonist and antagonist muscle responsible for movement production. Few studies investigated the influence of antagonist stretching on exercise performance. The purpose of this study is to examine the acute effects of antagonist stretching on agonist movement economy. 14 participants (5 male, 9 females; 168.32 ± 7.63 cm stature; 65.00 ± 7.28 kg mass) completed baseline active ROM (AROM) and passive ROM (PROM) measurements. The experimental design required participants to complete two 5 ...


Integrative Dance For Adults With Down Syndrome: Effects On Postural Stability, Sarah E. DiPasquale, Benjamin Canter, Mary Roberts 2020 Skidmore College

Integrative Dance For Adults With Down Syndrome: Effects On Postural Stability, Sarah E. Dipasquale, Benjamin Canter, Mary Roberts

International Journal of Exercise Science

International Journal of Exercise Science 13(3): 1317-1325, 2020. Postural stability, one’s ability to maintain an upright stable position, is a crucial aspect of functional mobility and independent living. The purpose of this study was to examine if integrative dance classes have the potential to improve the postural stability in individuals with Down syndrome (DS). Utilizing a one group design, seven participants with DS were evaluated before and after a 12-week integrative dance class (ClinicalTrials.gov#NCT03660423). Postural stability was evaluated in uni- and bilateral quiet standing using a Wii Balance Board. Stability levels were measured based on changes ...


A Comparative Analysis Of Army Body Composition Standards For Women, Adam G. Tedford, Veronika Pribyslavska, Lance G. Bryant, Eric M. Scudamore 2020 Arkansas State University

A Comparative Analysis Of Army Body Composition Standards For Women, Adam G. Tedford, Veronika Pribyslavska, Lance G. Bryant, Eric M. Scudamore

International Journal of Exercise Science

International Journal of Exercise Science 13(7): 1275-1282, 2020. The aim of this study was to compare body fat percentage (BF%) of women measured using the U.S. Army standard body composition assessment (ABC) and two common laboratory measures of body composition to evaluate the efficacy of ABC within this population. The BF% of 27 women (21.5 ± 1.8 years) was assessed using the 7-site skinfold, air plethysmography, and ABC measurements. The initial physical fitness test (IPFT) was used to determine if participants met the criteria required for admittance into basic combat training. A repeated measures ANOVA identified differences ...


Long-Term Tennis Participation And Health Outcomes: An Investigation Of “Lifetime” Activities, Katherine E. Spring, Megan E. Holmes, JohnEric W. Smith 2020 Auburn University

Long-Term Tennis Participation And Health Outcomes: An Investigation Of “Lifetime” Activities, Katherine E. Spring, Megan E. Holmes, Johneric W. Smith

International Journal of Exercise Science

International Journal of Exercise Science 13(7): 1251-1261, 2020. Lifetime sports, such as tennis, provide opportunities for participation throughout the lifespan and has been linked with lower risk of cardiovascular disease, obesity, and depression. The objective of this study was to consider the influence of chronic tennis participation on various parameters of health. Members of the International Tennis Federation (ITF) completed a survey consisting of questions from International Physical Activity Questionnaire (IPAQ), Behavior Risk Factor Surveillance System (BRFSS), Satisfaction With Life Survey (SWLS), and specific tennis participation questions. Descriptive characteristics were calculated for all variables and a chi-squared analysis was ...


Accuracy Of 5 Common Age-Predicted Maximal Heart Rate Equations, Daniel Shookster, Bryndan Lindsey, Nelson Cortes, Joel Martin 2020 George Mason University

Accuracy Of 5 Common Age-Predicted Maximal Heart Rate Equations, Daniel Shookster, Bryndan Lindsey, Nelson Cortes, Joel Martin

International Journal of Exercise Science

International Journal of Exercise Science 13(7): 1242-1250, 2020. Age-predicted maximal heart rate (APMHR) is an essential measure for healthcare professionals in determining cardiovascular response to exercise testing, exertion, and prescription. Although multiple APMHR prediction equations have been validated for specific populations, the accuracy of each within a general population requires testing. We aimed to determine which APMHR equation (Fox, Gellish, Gulati, Tanaka, Arena, Astrand, Nes, Fairbarn) most accurately predicts max heart rate (HRmax) in a general population. HRmax from 99 graded treadmill exercise tests (GXT) were measured. GXTs ended upon volitional fatigue and were only included for ...


Effects Of Three Modest Levels Of Proximal Loading On Marathon Pace Running Economy, Jackson W. Gaddie, Emily P. Kennedy, Matt Green, Lauren G. Killen, Braxton A. Linder, Angela A. Heinkel, Eric K. O'Neal 2020 University of North Alabama

Effects Of Three Modest Levels Of Proximal Loading On Marathon Pace Running Economy, Jackson W. Gaddie, Emily P. Kennedy, Matt Green, Lauren G. Killen, Braxton A. Linder, Angela A. Heinkel, Eric K. O'Neal

International Journal of Exercise Science

International Journal of Exercise Science 13(7): 1120-1131, 2020. This study examined the effect of modest increases in proximal body mass on running economy expressed as metabolic cost (MC). External loads of 1.6 (L), 2.4 (M), and 3.2 kg (H) were added to the anterior and posterior torso region of male (n = 18) and female (n = 18) runners using a double-layered compression garment with gel inserts. MC was evaluated using stoichiometry equations of data collected via indirect calorimetry. Data was collected during four, 5-min running bouts at marathon pace for the 3 load levels and an unloaded ...


Job-Specific Physical Fitness Changes Measured By The Work Sample Test Battery Within Deputy Sheriffs Between Training Academy And Their First Patrol Assignment, Robert G. Lockie, Rodney Pope, Olivia Saaroni, Joseph Dulla, J. Jay Dawes, Robin Marc Orr 2020 California State University, Fullerton

Job-Specific Physical Fitness Changes Measured By The Work Sample Test Battery Within Deputy Sheriffs Between Training Academy And Their First Patrol Assignment, Robert G. Lockie, Rodney Pope, Olivia Saaroni, Joseph Dulla, J. Jay Dawes, Robin Marc Orr

International Journal of Exercise Science

International Journal of Exercise Science 13(4): 1262-1274, 2020. Deputy Sheriffs need to exhibit job-specific fitness throughout their occupational lifespan. This study evaluated job-specific fitness changes measured by the Work Sample Test Battery (WSTB) in deputy sheriffs from training academy to patrol school (refresher program completed before first patrol assignment). WSTB data for 34 deputy sheriffs (28 males, 6 females) was retrospectively analyzed. The WSTB included five tests: a 99-yard obstacle course (99OC); a 165-pound body drag (BD); 6-foot chain link fence (CLF) and solid wall (SW) climbs; and a 500-yard run (500R). WSTB task times measured at the end ...


Effect Of Chronotype On Sleep Quality In A Laboratory Setting, Brianna D. Harfmann, Natashia Swalve, John Mitrzyk, Alex Montoye 2020 Alma College

Effect Of Chronotype On Sleep Quality In A Laboratory Setting, Brianna D. Harfmann, Natashia Swalve, John Mitrzyk, Alex Montoye

International Journal of Exercise Science

International Journal of Exercise Science 13(3): 1283-1294, 2020. Sleep is undoubtedly important for human health as insufficient sleep has been associated with a plethora of diseases. Adequate sleep assessment is critical in clinical and research settings, however current sleep assessment protocols fail to account for circadian rhythms, despite the fact that sleep is a well-recognized circadian process. Purpose: The purpose of this study was to determine if circadian parameters, such as chronotype, influence sleep quality in a sleep laboratory setting. Methods: In order to investigate this, twenty participants (10 men and 10 women) aged 18-31 years old had their ...


Esport: Fortnite Acutely Increases Heart Rate Of Young Men, Silvio Valladao, Jake Middleton, Thomas Andre 2020 University of Mississippi (Ole Miss)

Esport: Fortnite Acutely Increases Heart Rate Of Young Men, Silvio Valladao, Jake Middleton, Thomas Andre

International Journal of Exercise Science

International Journal of Exercise Science 13(6): 1217-1227, 2020. Esports has rapidly increased in online play and viewing. A myriad of literature focuses on heart rate (HR) during traditional athletic competition, little research has addressed the HR responses of individuals playing esports and none in the esport: Fortnite. The purpose of this study was to compare the HR response during a 3-hour seated session of the esport: Fortnite to resting HR. Male college students (n = 23; age = 21 ± 1.8 years; BMI = 25.7 ± 3.9; Esport mean hours per week = 13 ± 8.7) were recruited to participate in the ...


Patient And Provider Communication Regarding Exercise During Pregnancy In A Rural Setting, Maire M. Blankenship, Kim Link, Samantha Henry, Rachel A. Tinius 2020 Western Kentucky University, USA

Patient And Provider Communication Regarding Exercise During Pregnancy In A Rural Setting, Maire M. Blankenship, Kim Link, Samantha Henry, Rachel A. Tinius

International Journal of Exercise Science

International Journal of Exercise Science 13(3): 1228-1241, 2020. Women in rural settings are at increased risk for adverse pregnancy outcomes. One potential way to improve pregnancy outcomes in rural settings is through physical activity promotion. However, given the disparities in prenatal care, women in rural areas may not receive information from their health care provider regarding physical activity during pregnancy. Therefore, the purpose of this study was to examine patient and provider communication in a rural setting (both patients’ and providers’ perspectives) regarding physical activity during pregnancy. A mixed methods study was performed among patients and providers in an ...


Nano-Vesicle (Mis)Communication In Senescence-Related Pathologies, Sherin Saheera, Ajay Godwin Potnuri, Prasanna Krishnamurthy 2020 University of Massachusetts Medical School

Nano-Vesicle (Mis)Communication In Senescence-Related Pathologies, Sherin Saheera, Ajay Godwin Potnuri, Prasanna Krishnamurthy

COVID-19 Publications by UMMS Authors

Extracellular vesicles are a heterogeneous group of cell-derived membranous structures comprising of exosomes, apoptotic bodies, and microvesicles. Of the extracellular vesicles, exosomes are the most widely sorted and extensively explored for their contents and function. The size of the nanovesicular structures (exosomes) range from 30 to 140 nm and are present in various biological fluids such as saliva, plasma, urine etc. These cargo-laden extracellular vesicles arise from endosome-derived multivesicular bodies and are known to carry proteins and nucleic acids. Exosomes are involved in multiple physiological and pathological processes, including cellular senescence. Exosomes mediate signaling crosstalk and play a critical role ...


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