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Capacitive Memory Alters Alternans And Spontaneous Activity In A Minimal Cardiomyocyte Model, Tien Comlekoglu, Seth H. Weinberg 2017 Virginia Commonwealth University

Capacitive Memory Alters Alternans And Spontaneous Activity In A Minimal Cardiomyocyte Model, Tien Comlekoglu, Seth H. Weinberg

Biology and Medicine Through Mathematics Conference

No abstract provided.


Follicular Dynamics In Insulin Resistant Mares, Julio Cesar Prado 2016 University of Tennessee, Knoxville

Follicular Dynamics In Insulin Resistant Mares, Julio Cesar Prado

Masters Theses

Obesity and insulin resistance have been linked to prolonged interovulatory period, aberrations in the estrous cycle, and continuous reproductive activity during the non-breeding season. EMS has been determined to influence the intrafollicular environment of mare ovaries. In humans, insulin resistance has been linked to polycystic ovaries as part of Polycystic Ovarian Syndrome (PCOS). A study was conducted to determine 1) the impact of insulin resistance on follicle growth and size at ovulation, and 2) whether predicted ovulatory follicles respond to hCG administration in Insulin-resistant (IR) mares. Mares were selected for the study based on insulin sensitivity and separated into an ...


Examining The Combined Effects Of Dissolved Oxygen, Temperature, And Body Size On The Physiological Responses Of A Model Macrobenthic Polychaete Species, Capitella Teleta, Kelsey Burns Gillam 2016 University of Southern Mississippi

Examining The Combined Effects Of Dissolved Oxygen, Temperature, And Body Size On The Physiological Responses Of A Model Macrobenthic Polychaete Species, Capitella Teleta, Kelsey Burns Gillam

Dissertations

While the scientific community is in consensus that coastal systems are threatened by climate change, few climate change studies test the effects of more than one variable directly related to climate change. The dissolved oxygen (DO) levels of the ocean are currently subject to both global warming and eutrophication; 94% of all hypoxia zones are expected to experience >2°C increase by 2035. This dissertation aims to examine how a model organism responds to simultaneous thermal and DO stress involving four levels of DO (100%, 70%, 50%, and 20%) saturation and three temperatures (15°C, 20°C, and 25°C ...


Early Nutritional Programming To Enhance The Utilization Of Plant Based Diets In Fish (Largemouth Bass, Micropterus Salmoides), Maya Rene Jackson, Cora Teets, Amit Kumar Yadav, Waldemar Rossi 2016 Kentucky State University

Early Nutritional Programming To Enhance The Utilization Of Plant Based Diets In Fish (Largemouth Bass, Micropterus Salmoides), Maya Rene Jackson, Cora Teets, Amit Kumar Yadav, Waldemar Rossi

Posters-at-the-Capitol

Aquaculture has been the fastest growing animal food-producing sector for over half a century. Sustainable aquaculture should include replacement of fish-based feed sources by plant-based ingredients. However, this approach is often impeded by poor growth in carnivorous fish such as largemouth bass (LMB, Micropterus salmoides) fed high levels of plant-based protein. Therefore, our overall goal of the present work was to develop alternative methods of utilizing the plant-based diets (PBD) for sustainable LMB production. When fish is exposed to PBD early in their life, they may accept them more efficiently at later stages (so called Nutritional Programing, NP). Therefore, we ...


A 2-D Compartmental Model For Multi-Capillary Supply, Liang Sun, Junkoo Park, Alessandra L. Barrera 2016 Georgia Gwinnett College

A 2-D Compartmental Model For Multi-Capillary Supply, Liang Sun, Junkoo Park, Alessandra L. Barrera

Annual Symposium on Biomathematics and Ecology: Education and Research

No abstract provided.


Effects Of S1p Mutation On Er Stress And Cholesterol Synthesis Markers In Human Epithelial Cells, Connie Gan, George G. Schweitzer, Rita T. Brookheart, Robert C. Bucelli, Brian N. Finck 2016 Washington University in St. Louis

Effects Of S1p Mutation On Er Stress And Cholesterol Synthesis Markers In Human Epithelial Cells, Connie Gan, George G. Schweitzer, Rita T. Brookheart, Robert C. Bucelli, Brian N. Finck

Undergraduate Research Symposium Posters

Site-1 Protease (S1P) is a Golgi-resident enzyme required for activation and subsequent nuclear localization of several major transcription factors. A 24-year-old female patient with a de novo single point mutation in S1P presented with a complex phenotype of gut hypomotility, abnormal optic nerves, and polycystic ovarian syndrome. Furthermore, this patient suffers from phenotypes related to skeletal muscle dysfunction, resulting in decreased ability to perform physical exercise due to unusual post-exercise pain, fatigue, nausea, and vomiting. This phenomenon has been described in the literature to manifest from myoedema and the breakdown of muscle that releases intracellular proteins into the blood, or ...


Growth And Productivity Of Irrigated Rice (Oryza Sativa L.) For A Tropical High Altitude Environment In Rwanda, Elie Rene Gasore 2016 University of Arkansas, Fayetteville

Growth And Productivity Of Irrigated Rice (Oryza Sativa L.) For A Tropical High Altitude Environment In Rwanda, Elie Rene Gasore

Theses and Dissertations

Yield components, grain yield, biomass and plant N accumulation, and N fertilizer responses of irrigated rice (Oryza sativa, L.) were evaluated for a tropical inland valley environment in the high altitudes in Rwanda. Effects were measured for nitrogen (N) fertilizer rate (0, 60, 90,120,150,180 kg N ha-1), season, growth stage and cultivar of different subspecies and plant types during 2012 dry season (DS) and 2013 wet season (WS) at Cyili Rice Research Farm (1380 m above sea level). Variations in irradiance (17.2± 0.32 MJ m-2 day-1 in DS and 9.4 ± 0.66 MJ m-2 ...


Designing A Mobile Space Habitat Analog, Victor Kitmanyen, Matthew Burkhard, Timothy Disher 2016 Embry-Riddle Aeronautical University - Daytona Beach

Designing A Mobile Space Habitat Analog, Victor Kitmanyen, Matthew Burkhard, Timothy Disher

Human Factors and Applied Psychology Student Conference

No abstract provided.


Photosynthetic Acclimation To Warming And Elevated Co2 In Two Antarctic Vascular Plant Species, Vi NT Bui 2016 The University of Western Ontario

Photosynthetic Acclimation To Warming And Elevated Co2 In Two Antarctic Vascular Plant Species, Vi Nt Bui

Electronic Thesis and Dissertation Repository

Climate change can affect the performance of the only two vascular plant species found in Antarctica, Deschampsia antarctica and Colobanthus quitensis. I investigated the response of these two species to warming and elevated CO2 in terms of photosynthesis and leaf anatomy. While photosynthesis increased directly with rising temperature and CO2, it showed no acclimation to changes in growth temperature, and a small degree of acclimation to growth under elevated CO2. Likewise, leaf anatomy displayed little plasticity in response to changes in the growth environment, although D. antarctica’s stomatal groove structure was modified under warming, likely to ...


Success Stories And Emerging Themes In Conservation Physiology, Christine L. Madliger, Steven J. Cooke, Erica J. Crespi, Jennifer L. Funk, Kevin R. Hultine, Kathleen E. Hunt, Jason R. Rohr, Brent J. Sinclair, Cory D. Suski, Craig K. R. Willis, Oliver P. Love 2016 University of Windsor

Success Stories And Emerging Themes In Conservation Physiology, Christine L. Madliger, Steven J. Cooke, Erica J. Crespi, Jennifer L. Funk, Kevin R. Hultine, Kathleen E. Hunt, Jason R. Rohr, Brent J. Sinclair, Cory D. Suski, Craig K. R. Willis, Oliver P. Love

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The potential benefits of physiology for conservation are well established and include greater specificity of management techniques, determination of cause–effect relationships, increased sensitivity of health and disturbance monitoring and greater capacity for predicting future change. While descriptions of the specific avenues in which conservation and physiology can be integrated are readily available and important to the continuing expansion of the discipline of ‘conservation physiology’, to date there has been no assessment of how the field has specifically contributed to conservation success. However, the goal of conservation physiology is to foster conservation solutions and it is therefore important to assess ...


Sensory Modalities Underlying The Escape Response Of The Cricket, Acheta Domesticus, To Looming Stimuli, Ariel M. Childs 2016 James Madison University

Sensory Modalities Underlying The Escape Response Of The Cricket, Acheta Domesticus, To Looming Stimuli, Ariel M. Childs

Senior Honors Projects

In order to prevent injury or capture by a predator, animals have evolved escape behavior. Despite offering a more realistic, multimodal, approximation of an approaching predator, looming stimuli have rarely been used to evoke escape behavior in crickets. Wind stimuli, however, have been used on a variety of insects, including crickets where it has been found that direction of escape is directly correlated to the angle of incoming wind stimuli. Wind stimuli are detected by sensilla trichodea, small filiform hairs covering the cerci of crickets, locusts and cockroaches. Despite having other complex sensory systems, such as antennae and vision, little ...


Changes In Brain Water Content In The Rainbow Trout (Oncorhynchus Mykiss) And In The Goldfish (Carassius Auratus) Due To High External Ammonia Exposure, Phillip Q.H. Pham-Ho 2016 Wilfrid Laurier University

Changes In Brain Water Content In The Rainbow Trout (Oncorhynchus Mykiss) And In The Goldfish (Carassius Auratus) Due To High External Ammonia Exposure, Phillip Q.H. Pham-Ho

Theses and Dissertations (Comprehensive)

In fishes, hyperammonemia may occur following feeding or exposure to abnormally high concentrations of environmental ammonia due to sewage effluents, agricultural run-off and in crowded aquaculture pens. Increased internal ammonia can result in hyperactivity, convulsions, coma and death. In mammals, it is also associated with potentially fatal brain edema, in which the accumulation of intracellular water results in swelling, increased intracranical pressure and herniation leading to death. Recently it was shown that rainbow trout (Oncorhynchus mykiss) and goldfish (Carassius auratus) experience brain swelling following exposure to high external ammonia (HEA). However, the mechanism of ammonia-induced brain swelling in fishes remains ...


Long-Term, High Frequency In Situ Measurements Of Intertidal Mussel Bed Temperatures Using Biomimetic Sensors, Brian Helmuth, Francis Choi, Allison Matzelle, Jessica Torossian, Scott Morello, K.A.S. Mislan, Lauren Yamane, Denise Strickland, P. Szathmary, Sarah Gilman, Alyson Tockstein, Thomas Hilbish, Michael Burrows, Anne Marie Power, Elizabeth Gosling, Nova Mieszkowska, Christopher Harley, Michael Nishizaki, Emily Carrington, Bruce Menge, Laura Petes, Melissa Foley, Angela Johnson, Megan Poole, Mae Noble, Erin Richmond, Matt Robart, Jonathan Robinson, Jerod Sapp, Jackie Sones, Bernardo Broitman, Mark Denny, Katharine Mach, Luke P. Miller, Michael O'Donnell, Philip Ross, Gretchen Hofmann, Mackenzie Zippay, Carol Blanchette, J. Macfarlan, Eugenio Carpizo-Ituarte, Benjamin Ruttenberg, Carlos Peña Mejía, Christopher McQuaid, Justin Lathlean, Cristián Monaco, Katy Nicastro, Gerardo Zardi 2016 Northeastern University

Long-Term, High Frequency In Situ Measurements Of Intertidal Mussel Bed Temperatures Using Biomimetic Sensors, Brian Helmuth, Francis Choi, Allison Matzelle, Jessica Torossian, Scott Morello, K.A.S. Mislan, Lauren Yamane, Denise Strickland, P. Szathmary, Sarah Gilman, Alyson Tockstein, Thomas Hilbish, Michael Burrows, Anne Marie Power, Elizabeth Gosling, Nova Mieszkowska, Christopher Harley, Michael Nishizaki, Emily Carrington, Bruce Menge, Laura Petes, Melissa Foley, Angela Johnson, Megan Poole, Mae Noble, Erin Richmond, Matt Robart, Jonathan Robinson, Jerod Sapp, Jackie Sones, Bernardo Broitman, Mark Denny, Katharine Mach, Luke P. Miller, Michael O'Donnell, Philip Ross, Gretchen Hofmann, Mackenzie Zippay, Carol Blanchette, J. Macfarlan, Eugenio Carpizo-Ituarte, Benjamin Ruttenberg, Carlos Peña Mejía, Christopher Mcquaid, Justin Lathlean, Cristián Monaco, Katy Nicastro, Gerardo Zardi

Faculty Publications

At a proximal level, the physiological impacts of global climate change on ectothermic organisms are manifest as changes in body temperatures. Especially for plants and animals exposed to direct solar radiation, body temperatures can be substantially different from air temperatures. We deployed biomimetic sensors that approximate the thermal characteristics of intertidal mussels at 71 sites worldwide, from 1998-present. Loggers recorded temperatures at 10–30 min intervals nearly continuously at multiple intertidal elevations. Comparisons against direct measurements of mussel tissue temperature indicated errors of ~2.0–2.5 °C, during daily fluctuations that often exceeded 15°–20 °C. Geographic patterns in ...


Long-Term, High Frequency In Situ Measurements Of Intertidal Mussel Bed Temperatures Using Biomimetic Sensors, Brian Helmuth, Francis Choi, Allison Matzelle, Jessica L. Torossian, Scott L. Morello, K.A.S. Mislan, Lauren Yamane, Denise Strickland, P. Lauren Szathmary, Sarah E. Gilman, Alyson Tockstein, Thomas J. Hilbish, Michael T. Burrows, Anne Marie Power, Elizabeth Gosling, Nova Mieszkowska, Christopher D.G. Harley, Michael Nishizaki, Emily Carrington, Bruce Menge, Laura Petes, Melissa M. Foley, Angela Johnson, Megan Poole, Mae M. Noble, Erin L. Richmond, Matt Robart, Jonathan Robinson, Jerod Sapp, Jackie Sones, Bernardo R. Broitman, Mark W. Denny, Katharine J. Mach, Luke P. Miller, Michael O'Donnell, Philip Ross, Gretchen E. Hofmann, Mackenzie Zippay, Carol Blanchette, J. A. Macfarlan, Eugenio Carpizo-Ituarte, Benjamin Ruttenberg, Carlos E. Peña Mejía, Christopher D. McQuaid, Justin Lathlean, Cristián J. Monaco, Katy R. Nicastro, Gerardo Zardi 2015 Northeastern University

Long-Term, High Frequency In Situ Measurements Of Intertidal Mussel Bed Temperatures Using Biomimetic Sensors, Brian Helmuth, Francis Choi, Allison Matzelle, Jessica L. Torossian, Scott L. Morello, K.A.S. Mislan, Lauren Yamane, Denise Strickland, P. Lauren Szathmary, Sarah E. Gilman, Alyson Tockstein, Thomas J. Hilbish, Michael T. Burrows, Anne Marie Power, Elizabeth Gosling, Nova Mieszkowska, Christopher D.G. Harley, Michael Nishizaki, Emily Carrington, Bruce Menge, Laura Petes, Melissa M. Foley, Angela Johnson, Megan Poole, Mae M. Noble, Erin L. Richmond, Matt Robart, Jonathan Robinson, Jerod Sapp, Jackie Sones, Bernardo R. Broitman, Mark W. Denny, Katharine J. Mach, Luke P. Miller, Michael O'Donnell, Philip Ross, Gretchen E. Hofmann, Mackenzie Zippay, Carol Blanchette, J. A. Macfarlan, Eugenio Carpizo-Ituarte, Benjamin Ruttenberg, Carlos E. Peña Mejía, Christopher D. Mcquaid, Justin Lathlean, Cristián J. Monaco, Katy R. Nicastro, Gerardo Zardi

Luke P. Miller

At a proximal level, the physiological impacts of global climate change on ectothermic organisms are manifest as changes in body temperatures. Especially for plants and animals exposed to direct solar radiation, body temperatures can be substantially different from air temperatures. We deployed biomimetic sensors that approximate the thermal characteristics of intertidal mussels at 71 sites worldwide, from 1998-present. Loggers recorded temperatures at 10–30 min intervals nearly continuously at multiple intertidal elevations. Comparisons against direct measurements of mussel tissue temperature indicated errors of ~2.0–2.5 °C, during daily fluctuations that often exceeded 15°–20 °C. Geographic patterns in ...


Longevity Of Mineral Supplements Within The Soil And Associated Use By White-Tailed Deer, Brian C. Peterson, Keith D. Koupal, Andrew K. Schissel, Cody M. Siegel 2015 University of Nebraska Kearney

Longevity Of Mineral Supplements Within The Soil And Associated Use By White-Tailed Deer, Brian C. Peterson, Keith D. Koupal, Andrew K. Schissel, Cody M. Siegel

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

Humans have baited wildlife such as white-tailed deer (Odocoileus virginianus) for generations with the primary purpose of increasing hunting harvest success. Baiting regulation changes are often considered by state management agencies as they pertain to hunting opportunity, fair chase, and disease risk. Cervids require a variety of minerals to supplement biological processes, especially sodium (Na), calcium (Ca), and phosphorus (P). We developed artificial mineral supplement sites set in front of trail cameras to monitor deer use. Pooled soil samples were collected at mineral sites and compared to the surrounding area to determine the longevity of elevated minerals levels within the ...


Cardioprotective Role Of The Cholinergic System, Mouhamed Dakroub 2015 The University of Western Ontario

Cardioprotective Role Of The Cholinergic System, Mouhamed Dakroub

Electronic Thesis and Dissertation Repository

The process of aging is an irreversible continuum experienced by all individuals. A large number of physiological transformations occur to the cardiovascular system as one ages. These changes result in increased risk of developing cardiovascular diseases, many of which are frequently seen in geriatric populations. While the exact mechanisms of age-related cardiac dysfunction have not been established, abnormal cholinergic dysfunction has been implicated in the pathology of other age related diseases; therefore, we have hypothesized that age induced cholinergic dysfunction is detrimental to cardiac function and health. This study seeks to identify whether increased cholinergic signaling, either by transgenic overexpression ...


Cardiovascular Regulation And Effects Of Respiratory Motor Training In Patients With Chronic Spinal Cord Injury., Bonnie Legg Ditterline 2015 University of Louisville

Cardiovascular Regulation And Effects Of Respiratory Motor Training In Patients With Chronic Spinal Cord Injury., Bonnie Legg Ditterline

Electronic Theses and Dissertations

This dissertation attempts to discover the mechanisms between cardiovascular and respiratory motor control post spinal cord injury (SCI): in normal, non-injured (NI) persons, cardiovascular regulation is dependent upon respiration, but there is nothing that suggests the mechanism for this relationship post-SCI. Thus we hoped to evaluate various aspects of cardiovascular regulation to further illustrate how this relationship is changed or unchanged by SCI. Chapter I describes the anatomy and physiology of the spine, respiratory system, and cardiovascular system in a NI person, and then describes how the function of these systems is changed by SCI. In addition, we describe therapies ...


Effects Of Supplemental Hydration On Physiology And Behavior Of Northern Pacific Rattlesnakes (Crotalus Oreganus Oreganus), Griffin D. Capehart 2015 California Polytechnic State University - San Luis Obispo

Effects Of Supplemental Hydration On Physiology And Behavior Of Northern Pacific Rattlesnakes (Crotalus Oreganus Oreganus), Griffin D. Capehart

Master's Theses and Project Reports

Hydration is a critical element for many physiological processes in vertebrates, such as protein production, innate immunity, and behavioral processes such as daily activity and thermoregulation. Few studies have directly assessed the effect of hydration on these animals in nature. While it seems intuitive that drought is stressful to animals, studies examining drought are typically observational and fail to assess how the hydration state of these animals influences their physiology and behavior. We tested for an effect of hydration on several physiological and behavioral parameters in Northern Pacific rattlesnakes (Crotalus oreganus oreganus) by experimentally manipulating hydration levels in the field ...


Salivary Vip Concentrations Are Elevated In Humans After Acute Stress, Giovanni Ventre 2015 Seton Hall University

Salivary Vip Concentrations Are Elevated In Humans After Acute Stress, Giovanni Ventre

Seton Hall University Dissertations and Theses (ETDs)

The purpose of this research was to evaluate two salivary neuropeptides in the context of the stress response. The research was focused first and foremost on evaluating the usefulness of salivary Neuropeptide Y (NPY) and salivary vasoactive intestinal peptide (VIP) as stress indicators. Secondly, we questioned whether these markers help us in distinguishing between physical and psychological stress. Psychological stress can be experienced in a situation such as that in anticipation of an important exam or mental task. Physical stress can be experienced usually by strenuous exercise. Salivary NPY and salivary VIP are two neuropeptides that are released as a ...


Lh-Independent Testosterone Secretion Is Mediated By The Interaction Between Gnrh2 And Its Receptor Within Porcine Testes, Amy T. Desaulniers, Rebecca A. Cederberg, Ginger A. Mills, J. Joe Ford, Clay A. Lents, Brett R. White 2015 University of Nebraska-Lincoln

Lh-Independent Testosterone Secretion Is Mediated By The Interaction Between Gnrh2 And Its Receptor Within Porcine Testes, Amy T. Desaulniers, Rebecca A. Cederberg, Ginger A. Mills, J. Joe Ford, Clay A. Lents, Brett R. White

Faculty Papers and Publications in Animal Science

Unlike classic gonadotropin-releasing hormone 1 (GNRH1), the second mammalian isoform (GNRH2) is an ineffective stimulant of gonadotropin release. Species that produce GNRH2 may not maintain a functional GNRH2 receptor (GNRHR2) due to coding errors. A full-length GNRHR2 gene has been identified in swine, but its role in reproduction requires further elucidation. Our objective was to examine the role of GNRH2 and GNRHR2 in testicular function of boars. We discovered that GNRH2 levels were higher in the testis than in the anterior pituitary gland or hypothalamus, corresponding to greater GNRHR2 abundance in the testis versus the anterior pituitary gland. Moreover, GNRH2 ...


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