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Serum Vitamin B12, And Related Mtrr And Cubilin Genotypes, Predict Neural Outcomes Across The Ad Spectrum, K. E. McLiman, A. D. Collazo Martinez, Jonathan P. Mochel, Karin D. Allenspach, Auriel A. Willette 2020 Iowa State University and Viterbo University

Serum Vitamin B12, And Related Mtrr And Cubilin Genotypes, Predict Neural Outcomes Across The Ad Spectrum, K. E. Mcliman, A. D. Collazo Martinez, Jonathan P. Mochel, Karin D. Allenspach, Auriel A. Willette

Biomedical Sciences Publications

Epidemiological studies show mixed findings for serum vitamin B12 and both cognitive and regional volume outcomes. No studies to date have comprehensively examined, in non-supplemented individuals, serum B12 level associations with neurodegeneration, hypometabolism, and cognition across the Alzheimer's disease (AD) spectrum. Serum vitamin B12 was assayed from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL). Voxel-wise analyses regressed B12 levels against regional gray matter (GM) volume and glucose metabolism (p


Mainstreaming Nutrition Services: Stabilization Centers And Outpatient Therapeutic Program Centers, Ashar Muhammad Malik 2020 Aga Khan University

Mainstreaming Nutrition Services: Stabilization Centers And Outpatient Therapeutic Program Centers, Ashar Muhammad Malik

Community Health Sciences

No abstract provided.


Protective Role Of Shiitake Mushroom-Derived Exosome-Like Nanoparticles In D-Galactosamine And Lipopolysaccharide-Induced Acute Liver Injury In Mice, Baolong Liu, Yizhu Lu, Xingyi Chen, Philma Glora Muthuraj, Xingzhi Li, Mahesh Pattabiraman, Janos Zempleni, Stephen D. Kachman, Sathish Kumar Natarajan, Jiujiu Yu 2020 University of Nebraska-Lincoln

Protective Role Of Shiitake Mushroom-Derived Exosome-Like Nanoparticles In D-Galactosamine And Lipopolysaccharide-Induced Acute Liver Injury In Mice, Baolong Liu, Yizhu Lu, Xingyi Chen, Philma Glora Muthuraj, Xingzhi Li, Mahesh Pattabiraman, Janos Zempleni, Stephen D. Kachman, Sathish Kumar Natarajan, Jiujiu Yu

Nutrition and Health Sciences -- Faculty Publications

Fulminant hepatic failure (FHF) is a rare, life-threatening liver disease with a poor prognosis. Administration of D-galactosamine (GalN) and lipopolysaccharide (LPS) triggers acute liver injury in mice, simulating many clinical features of FHF in humans; therefore, this disease model is often used to investigate potential therapeutic interventions to treat FHF. Recently, suppression of the nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome, was shown to alleviate the severity of GalN/LPS-induced liver damage in mice. Therefore, the goal of this study was to find dietary exosome-like nanoparticles (ELNs) with therapeutic potential in curbing FHF ...


Healthy Pregnancies And Essential Fats: Focus Group Discussions With Zambian Women On Dietary Need And Acceptability Of A Novel Rusf Containing Fish Oil Dha, Catherine Chunda-Liyoka, Mwansa Ketty Lubeya, Mercy Imakando, Sophia Kisling, Sonoor Majid, Mary Willis, Charles Wood, Chipepo Kankasa, Concetta C. DiRusso 2020 University of Zambia

Healthy Pregnancies And Essential Fats: Focus Group Discussions With Zambian Women On Dietary Need And Acceptability Of A Novel Rusf Containing Fish Oil Dha, Catherine Chunda-Liyoka, Mwansa Ketty Lubeya, Mercy Imakando, Sophia Kisling, Sonoor Majid, Mary Willis, Charles Wood, Chipepo Kankasa, Concetta C. Dirusso

Nutrition and Health Sciences -- Faculty Publications

Background: Nut butter-based Ready to Use Supplemental Foods (RUSF) are an effective way to add nutrients and calories to diets of malnourished and food insecure populations. The RUSF formulations have been further modified to add micronutrients including iron and folic acid needed during pregnancy and lactation. Because docosahexaenoic acid (DHA, C22:6 n-3) enhances fetal development and birth outcomes, it has been suggested that perhaps RUSF formulations for pregnancy should also include this Omega 3 fatty acid. The goal of the present study was to gain an understanding of Zambian women’s knowledge of nutritional needs in pregnancy through structured ...


The Effects Of Dietary Linoleic Acid And Hydrophilic Antioxidants On Basal, Peak, And Sustained Metabolism In Flight‐Trained European Starlings, Wales A. Carter, Kristen J. DeMoranville, Barbara J. Pierce, Scott R. McWilliams 2020 University of Rhode Island

The Effects Of Dietary Linoleic Acid And Hydrophilic Antioxidants On Basal, Peak, And Sustained Metabolism In Flight‐Trained European Starlings, Wales A. Carter, Kristen J. Demoranville, Barbara J. Pierce, Scott R. Mcwilliams

Biology Faculty Publications

Dietary micronutrients have the ability to strongly influence animal physiology and ecology. For songbirds, dietary polyunsaturated fatty acids (PUFAs) and antioxidants are hypothesized to be particularly important micronutrients because of their influence on an individual's capacity for aerobic metabolism and recovery from extended bouts of exercise. However, the influence of specific fatty acids and hydrophilic antioxidants on whole‐animal performance remains largely untested. We used diet manipulations to directly test the effects of dietary PUFA, specifically linoleic acid (18:2n6), and anthocyanins, a hydrophilic antioxidant, on basal metabolic rate (BMR), peak metabolic rate (PMR), and rates of fat catabolism ...


Cognitive Interpersonal Model For Anorexia Nervosa Revisited: The Perpetuating Factors That Contribute To The Development Of The Severe And Enduring Illness, Janet Treasure, Daniel Willmott, Suman Ambwani, Valentina Cardi, Danielle Clark Bryan, Katie Rowlands, Ulrike Schmidt 2020 Dickinson College

Cognitive Interpersonal Model For Anorexia Nervosa Revisited: The Perpetuating Factors That Contribute To The Development Of The Severe And Enduring Illness, Janet Treasure, Daniel Willmott, Suman Ambwani, Valentina Cardi, Danielle Clark Bryan, Katie Rowlands, Ulrike Schmidt

Faculty and Staff Publications By Year

The cognitive interpersonal model was outlined initially in 2006 in a paper describing the valued and visible aspects of anorexia nervosa (Schmidt and Treasure, 2006). In 2013, we summarised many of the cognitive and emotional traits underpinning the model (Treasure and Schmidt, 2013). In this paper, we describe in more detail the perpetuating aspects of the model, which include the inter- and intrapersonal related consequences of isolation, depression, and chronic stress that accumulate in the severe and enduring stage of the illness. Since we developed the model, we have been using it to frame research and development at the Maudsley ...


Appalachian Environmental Health Literacy: Building Knowledge And Skills To Protect Health, Anna G. Hoover, Annie Koempel, W. Jay Christian, Kimberly I. Tumlin, Kelly G. Pennell, Steven Evans, Malissa McAlister, Lindell E. Ormsbee, Dawn Brewer 2020 University of Kentucky College of Public Health

Appalachian Environmental Health Literacy: Building Knowledge And Skills To Protect Health, Anna G. Hoover, Annie Koempel, W. Jay Christian, Kimberly I. Tumlin, Kelly G. Pennell, Steven Evans, Malissa Mcalister, Lindell E. Ormsbee, Dawn Brewer

Journal of Appalachian Health

Environmental health literacy (EHL) is an emerging, multidisciplinary field that promotes understanding of how environmental exposures can affect human health. After discussing the regional relevance of environmental health knowledge and skills, this article describes three ongoing Appalachian projects that are focused on measuring and building EHL.


The Effects Of Asparagus Racemosus Supplementation Plus 8 Weeks Of Resistance Training On Muscular Strength And Endurance, John Paul V. Anders, Joshua L. Keller, Cory M. Smith, Ethan C. Hill PhD, Terry J. Housh, Richard J. Schmidt, Glen O. Johnson 2020 University of Nebraska-Lincoln

The Effects Of Asparagus Racemosus Supplementation Plus 8 Weeks Of Resistance Training On Muscular Strength And Endurance, John Paul V. Anders, Joshua L. Keller, Cory M. Smith, Ethan C. Hill Phd, Terry J. Housh, Richard J. Schmidt, Glen O. Johnson

Nutrition and Health Sciences -- Faculty Publications

Previous studies have demonstrated that ayurvedic ingredients exhibit ergogenic (performance enhancing) properties, however, no previous studies have examined the ergogenic potential of Asparagus racemosus. The purpose of the present study was to examine the ergogenic efficacy of supplementation with 500 mg·d−1 of A. racemosus during bench press training. Eighteen recreationally trained men (mean ± SD; age = 20.4 ± 0.5 yrs; height = 179.7 ± 1.5 cm; weight = 84.7 ± 5.7 kg) were randomly assigned either 500 mg·d−1 of A. racemosus (n = 10) or placebo (n = 8). An overlapping sample of 10 participants were used to ...


Changing Weight Management Self-Efficacy Among Obese Puerto Rican Adults: A Quantitative Study Using A Health Coaching Intervention, Richard Valentin Ayala, Josh Bernstein 2020 A.T. Still University

Changing Weight Management Self-Efficacy Among Obese Puerto Rican Adults: A Quantitative Study Using A Health Coaching Intervention, Richard Valentin Ayala, Josh Bernstein

Internet Journal of Allied Health Sciences and Practice

Purpose: Obesity and associated healthcare-related issues continue to increase. The prevalence of obesity is on the rise, which has led many health professionals to find ways to improve health interventions. Health coaching can be a viable tool to reduce the obesity epidemic. The purpose of this quantitative study was to investigate the effects of an 8-weekhealth coaching intervention in obese individuals from Puerto Rico and to determine if self-esteem and body image influence weight managementself-efficacy. Method: A pretest-posttest design using a weight management self-efficacy scale helped the researcher evaluate the effectof the coaching sessions. In addition, body image was measured ...


Dietary Quality Is Associated With Better Self-Efficacy And Depression In Patients With Fibromyalgia From A Comparative Effectiveness Trial: A Small Pilot Study, Andrew R. Beauchesne, Lori Lyn Price, Chenchen Wang, Mei Chung 2020 Tufts University School of Medicine, Boston, Massachusetts; Maine Medical Center, Portland, Maine

Dietary Quality Is Associated With Better Self-Efficacy And Depression In Patients With Fibromyalgia From A Comparative Effectiveness Trial: A Small Pilot Study, Andrew R. Beauchesne, Lori Lyn Price, Chenchen Wang, Mei Chung

Journal of Maine Medical Center

Background: Diet and exercise have been suggested as potentially beneficial for symptom management of fibromyalgia; however, data on the relationship between diet quality and fibromyalgia symptoms are limited.

Objective: To investigate diet quality and its relationship with 1) fibromyalgia impact, and 2) psychological health in patients with fibromyalgia who participated in a randomized controlled trial (RCT) of Tai Chi versus aerobic exercise for fibromyalgia.

Methods: A cross-sectional study enrolled participants from a RCT. Diet quality and fibromyalgia symptoms were assessed using the Healthy Eating Index 2010 (HEI-2010) and Revised Fibromyalgia Impact Questionnaire (FIQR), respectively. Retrospective analyses were performed using Spearman ...


Alpha-Linolenic Acid-Enriched Butter Promotes Fatty Acid Remodeling And Thermogenic Activation In The Brown Adipose Tissue, Mikyoung You, Rong Fan, Judy Kim, Seung-Ho Shin, Soonkyu Chung 2020 University of Nebraska-Lincoln

Alpha-Linolenic Acid-Enriched Butter Promotes Fatty Acid Remodeling And Thermogenic Activation In The Brown Adipose Tissue, Mikyoung You, Rong Fan, Judy Kim, Seung-Ho Shin, Soonkyu Chung

Nutrition and Health Sciences -- Faculty Publications

Supplementation with n-3 long-chain (LC) polyunsaturated fatty acids (PUFA) is known to promote thermogenesis via the activation of brown adipose tissue (BAT). Agricultural products that are biofortified with α-linolenic acid (ALA), the precursor of n-3 LC PUFA, have been launched to the market, but their impact on BAT function is unknown. This study aimed to evaluate the effects of ALA-biofortified butter on lipid metabolism and thermogenic functions in the BAT. C57BL/6 mice were fed a high-fat diet containing ALA-biofortified butter (n3Bu, 45% calorie from fat) for ten weeks in comparison with the isocaloric high-fat diets prepared from conventional butter ...


Biology 4920g: Companion Planting In The Community, Jacquline A. Nathaniel 2020 Western University

Biology 4920g: Companion Planting In The Community, Jacquline A. Nathaniel

Community Engaged Learning Final Projects

LIFE*SPIN is a local organization in London, Ontario that provides resources to individuals and families dependent on low income to ultimately break the poverty cycle by encouraging sustainable living and self-sufficiency. For this Seminar in Biology course, Maria Bata and I partnered with LIFE*SPIN to plan and execute a "Seeding Planting Party" to teach children about basic botany, nutrition, and leadership. The following final paper for this seminar discusses the project deliverables and efforts, biological research concerning companion planting, and personal reflection on this experience.


Association Of Home Food Availability With Prediabetes And Diabetes Among Adults In The United States, Jennifer R. McAtee, Meng-Hua Tao, Christian King, Weiwen Chai 2020 University of Nebraska-Lincoln

Association Of Home Food Availability With Prediabetes And Diabetes Among Adults In The United States, Jennifer R. Mcatee, Meng-Hua Tao, Christian King, Weiwen Chai

Nutrition and Health Sciences -- Faculty Publications

This study examined associations of home food availabilities with prediabetes and diabetes among 8929 adults (20–70 years) participating in 2007–2010 National Health and Nutrition Examination Surveys. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were estimated by logistic regression. Relative to non-diabetic participants (individuals without diabetes or prediabetes), prediabetes participants were associated with lower availabilities of green vegetables (OR = 0.82; 95% CI = 0.73–0.91; p = 0.0006) and fat-free/low-fat milk (OR = 0.80, 95% CI = 0.65–0.89; p = 0.001) and higher sugary drink availability (OR = 1.24, 95% CI = 1 ...


Nurse Driven Enteral Nutrition Protocol For Mechanically Ventilated Patients, Deena Shewekah 2020 University of Kentucky

Nurse Driven Enteral Nutrition Protocol For Mechanically Ventilated Patients, Deena Shewekah

DNP Projects

Introduction: Delayed enteral nutrition in critically ill patients increases the risk of complications and poor outcomes. Current evidence-based guidelines recommend initiation of enteral nutrition within 24-48 hours of intensive care unit (ICU) admission. The quality improvement (QI) project aim was to examine whether enteral nutrition was initiated within 24- 48 hours of mechanical ventilation after implementation of QI intervention in order to determine practice change.

Methods: The QI protocol was introduced to the Cardiovascular ICU (CVICU) at UK Chandler Hospital (UKHC) nurses via an education session. A post-education electronic survey identified the nurse’s understanding of the protocol. To identify ...


Non-Invasive Method For Leptin Supplementation In Zebrafish (Danio Rerio), Regan McNamara 2020 The University of Akron

Non-Invasive Method For Leptin Supplementation In Zebrafish (Danio Rerio), Regan Mcnamara

Williams Honors College, Honors Research Projects

I tested the hypothesis that recombinant leptin protein can be introduced to zebrafish in vivo through non-invasive soaking in a solution containing the protein. One way to study various molecules’ effects in vivo is through intraperitoneal or intracerebroventricular injections during the embryonic or larval stage, which is invasive, difficult to administer, and can have a high mortality rate. 48 hours post fertilization (hpf) zebrafish were soaked in a His-tagged recombinant leptin protein solution at 10 nM and 100 nM concentrations (produced by Genscript). After soaking, zebrafish larvae were washed extensively to remove all recombinant protein on their exterior before homogenization ...


The Influence Of Diet On The Gut Microbiome, Kayla Wede 2020 South Dakota State University

The Influence Of Diet On The Gut Microbiome, Kayla Wede

Health and Nutritional Sciences Graduate Students Plan B Capstone Projects

There is growing research that directly looks at the relationship between the human diet and the gut microbiome. This paper is a narrative review of the current literature on how the human diet can influence the gut microbiome. Without a healthy gut, bacterial imbalances can occur which have been linked to health complications. There are many factors that affect the gut microbiome such as diet, medications, and exercise. There is also limited research that looks at the macronutrients and their role in gut health. It is known that the type of food that people consume is a major influencer of ...


The Effects Of A High-Fat Diet On The Brain; A Meta-Analysis Of Microglia In The Hypothalamus, Emily Karabeika 2020 Regis University

The Effects Of A High-Fat Diet On The Brain; A Meta-Analysis Of Microglia In The Hypothalamus, Emily Karabeika

All Regis University Theses

The typical ‘Western Diet’ includes a diet high in fats and sugars. This thesis explores the problems that this type of diet could have on the brain. A meta-analysis was conducted to show activated microglia count in the hypothalamus of mice after a high-fat diet. The results showed a large effect size with the included studies, showing that a high fat diet significantly increases microglia count across studies. Increased activated microglia leads to chronic inflammation in the hypothalamus, which is linked to metabolic problems like insulin resistance, leptin resistance and glucose intolerance.


Resource Selection And Calving Success Of Moose In Colorado, Forest P. Hayes 2020 University of Montana, Missoula

Resource Selection And Calving Success Of Moose In Colorado, Forest P. Hayes

Graduate Student Theses, Dissertations, & Professional Papers

Across much of North America, moose populations (Alces alces) are declining due to disease, predation, climate, and anthropogenic pressures. Despite this, populations of moose in Colorado have continued to grow. Studying successful (i.e., persistent or growing) populations of moose can facilitate the continued conservation of the species by identifying habitat features critical for moose persistence.

First, I evaluated calving success of moose in Colorado and the impact of willow habitat quality and nutrition. I then estimated the probability of female moose having a calf using repeated observations in a Bayesian occupancy model. I assigned values for dry matter digestibility ...


Effects Of A Campus Dining Tour Intervention On First Year Students Perception Of Healthfulness Of Environment, Paige Pappadackis 2020 South Dakota State University

Effects Of A Campus Dining Tour Intervention On First Year Students Perception Of Healthfulness Of Environment, Paige Pappadackis

Electronic Theses and Dissertations

Many young adults experience unwanted weight gain upon entering college. Making healthy choices in a food environment with a plethora of convenience and fast foods is important for preventing unwanted weight gain. The objective of this study was to determine if a Healthy Campus Dining Tour intervention improves perception, behavior, and priorities related to healthier choices on campus. Participants were recruited for this quasi-experimental study from freshman introductory classes at a land-grant public university and assigned to intervention or a control group. Intervention participants completed a 50-minute Healthy Campus Dining Tour that educated on how to make healthier choices at ...


Kibble Me This: The Scientific And Cultural Debate Over Boutique, Exotic, And Grain-Free Canine Nutrition, Anne Shalamoff 2020 Claremont Colleges

Kibble Me This: The Scientific And Cultural Debate Over Boutique, Exotic, And Grain-Free Canine Nutrition, Anne Shalamoff

Scripps Senior Theses

The relationship between humans and our canine companions goes back tens of thousands of years but commercial pet food is a relatively new phenomenon that has existed for less than two hundred. In a world of automation, mass-production, and global trade, factory scraps have replaced table scraps as the staple diet for dogs. Health issues, recall scares, changing human-dog relationships, and other social and political factors prompted dedicated pet owners to question the mysterious ingredients in their dog’s food and seek alternatives to mainstream kibble. This trend was halted by a report published in the summer of 2018 by ...


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