Flanker Task Performance In Young And Older Adults: A Behavioral And Erp Study, 2024 The Graduate Center, City University of New York
Flanker Task Performance In Young And Older Adults: A Behavioral And Erp Study, Fatima Medrano
Dissertations, Theses, and Capstone Projects
Research suggests that as we get older, executive function abilities decline (Hasher & Zacks, 1988; Salthouse, 1996). One affected ability is that of inhibitory control, which aids in monitoring our responses to non-target stimuli or information. Current research on inhibition reveals inconsistencies across studies. Monitoring brain responses during the Flanker (used to measure inhibitory control) task may add valuable insight into the processes underlying group differences behaviorally, by studying the N200 and P300 event-related potentials which have been associated with inhibitory control processes. This study investigated whether there are differences between older and younger adults in inhibitory control and whether …
Cross-Linguistic Differences In Neural Encoding And Processing Of Stop Consonants: The Impact Of Language Experience On Attention Allocation, 2024 The Graduate Center, City University of New York
Cross-Linguistic Differences In Neural Encoding And Processing Of Stop Consonants: The Impact Of Language Experience On Attention Allocation, Aline Dos Santos Oliveira
Dissertations, Theses, and Capstone Projects
This study aims to examine the intricate relationship between language experience and the neural processing of stop consonant speech sounds. Previous research has shown minimal differences in amplitudes and latencies of cortical Auditory Evoked Potentials (AEPs) to speech sounds across listeners from various language backgrounds. It is only towards the later latencies (around the P2 peak at 200 ms), that there have been suggestions of cross-linguistic differences. In addition, a recent study, observed an AEP difference between monolinguals and bilinguals when processing speech, specifically an "Nd effect”. The Nd effect, which is an increased negativity of the AEP is proposed …
How Sensory Exploration Using Expressive Arts Provides A Cohesive Experience For Children With Multiple Diagnoses, 2024 Lesley University
How Sensory Exploration Using Expressive Arts Provides A Cohesive Experience For Children With Multiple Diagnoses, Chanelle Goguen
Expressive Therapies Capstone Theses
This thesis looks at the potential benefits and cohesive experience of sensory exploration for children with multiple diagnoses through a trauma informed lens. The researcher was inspired by Prendiville’s (2021) idea of how interactive sensory exploration and art making can help foster and develop reciprocal communication and socio-affective relationships influenced the researcher to design a method that would be used to collect data about potential similar findings. In the method, the interaction of the sensory-specific art mediums were reflected through the expressive therapies continuum (ETC) framework. The research of this thesis acknowledges and explores how trauma and adverse childhood experiences …
Towards A New Role Of Mitochondrial Hydrogen Peroxide In Synaptic Function, 2024 CUNY Bernard M Baruch College
Towards A New Role Of Mitochondrial Hydrogen Peroxide In Synaptic Function, Cliyahnelle Z. Alexander
Student Theses and Dissertations
Aerobic metabolism is known to generate damaging ROS, particularly hydrogen peroxide. Reactive oxygen species (ROS) are highly reactive molecules containing oxygen that have the potential to cause damage to cells and tissues in the body. ROS are highly reactive atoms or molecules that rapidly interact with other molecules within a cell. Intracellular accumulation can result in oxidative damage, dysfunction, and cell death. Due to the limitations of H2O2 (hydrogen peroxide) detectors, other impacts of ROS exposure may have been missed. HyPer7, a genetically encoded sensor, measures hydrogen peroxide emissions precisely and sensitively, even at sublethal levels, during …
Astrocyte Spatial Distribution Affects Growth Dynamics Of Breast Cancer Brain Metastases: An Agent-Based Modeling Study, 2024 Virginia Commonwealth University
Astrocyte Spatial Distribution Affects Growth Dynamics Of Breast Cancer Brain Metastases: An Agent-Based Modeling Study, Rupleen Kaur
Biology and Medicine Through Mathematics Conference
No abstract provided.
Modeling Human Temporal Eeg Responses To Vr Visual Stimuli, 2024 Virginia Commonwealth University
Modeling Human Temporal Eeg Responses To Vr Visual Stimuli, Richard R. Foster, Connor Delaney, Dean J. Krusienski, Cheng Ly
Biology and Medicine Through Mathematics Conference
No abstract provided.
Understanding Stress-Induced Alterations In Microglia Density In The Medial Prefrontal Cortex Of Male And Female S1pr3gr-/Gr- Rats, 2024 Drexel University College of Medicine
Understanding Stress-Induced Alterations In Microglia Density In The Medial Prefrontal Cortex Of Male And Female S1pr3gr-/Gr- Rats, Jason Yan, Seema Bhatnagar, Brian Corbett
St. Chris Research Day
No abstract provided.
Spike Timing-Dependent Plasticity And Synaptic Scaling Invoke Episodic Bursting In An Excitatory Recurrent Neuronal Population, 2024 Virginia Commonwealth University
Spike Timing-Dependent Plasticity And Synaptic Scaling Invoke Episodic Bursting In An Excitatory Recurrent Neuronal Population, Ryno Chen, Gregory D. Conradi Smith
Biology and Medicine Through Mathematics Conference
No abstract provided.
Comparing Executive Control: Bilingualism's Cognitive Advantage, 2024 CWU
Comparing Executive Control: Bilingualism's Cognitive Advantage, Malcolm Jasmin, Tonya Buchanan Ph.D.
Symposium Of University Research and Creative Expression (SOURCE)
The Stroop Task is a widely used method for studying executive control. It helps to understand cognitive processes like inhibition and attentional regulation to examine how reading text and naming colors can interfere with each other. The study intends to use the Stroop Task to explore the executive control abilities of both bilingual and monolingual individuals. Previous research has shown that bilingual individuals perform better in the Stroop test compared to those who only speak one language (Bialystok et al., 2010). The impact of this advantage is believed to be due to the need to switch between languages and prevent …
Screen For Beneficial Genetic And Chemical Modifiers In Drosophila Models Of Als And Traumatic Brain Injury, 2024 Southern Methodist University
Screen For Beneficial Genetic And Chemical Modifiers In Drosophila Models Of Als And Traumatic Brain Injury, Will Bonderer
Biological Sciences Theses and Dissertations
The underlying molecular processes of aberrant protein expression in neurodegeneration are intricate and multifaceted, with ribosome-associated quality control (RQC) emerging as a promising avenue of exploration. Ribosome-associated quality control is integral to cellular function. Its evolutionarily conserved pathway encompasses a network of mechanisms designed to ensure the fidelity of protein synthesis, folding, and degradation within the cells of all eukaryotes. The ribosome, central to protein synthesis, plays a pivotal role in this quality control network, and its malfunction can lead to the accumulation of misfolded or aberrant proteins. In the context of neurodegenerative disorders, this dysfunction can have dire consequences. …
Estrogen Replacement Therapy To Reduce Neurodegeneration And Socio-Cognitive Deficits In A Female Sprague Dawley Rat Model Of Early-Onset Alzheimer’S Disease, 2024 Trinity College
Estrogen Replacement Therapy To Reduce Neurodegeneration And Socio-Cognitive Deficits In A Female Sprague Dawley Rat Model Of Early-Onset Alzheimer’S Disease, Miriam Kirylo
Senior Theses and Projects
No abstract provided.
The Development Of Immunohistochemistry (Icc) And Transcriptomic Protocols To Uncover Neurophysiological Markers Of Stress In Red-Eyed Tree Frogs As A Novel Biome, 2024 Trinity College
The Development Of Immunohistochemistry (Icc) And Transcriptomic Protocols To Uncover Neurophysiological Markers Of Stress In Red-Eyed Tree Frogs As A Novel Biome, Shirin Dadina
Senior Theses and Projects
Adverse childhood experiences (ACEs) include various forms of physical and emotional abuse that lead to detrimental long term effects. Agalychnis callidryas (red-eyed tree frogs) have been identified as a novel biomedical model for ACEs. Red-eyed tree frogs demonstrate an escape hatch mechanism under stressors including those from predators, flooding and hypoxia where the embryo undergoes an accelerated developmental process similar to what is observed in the human population regarding precocious puberty. In order to assess this model for neurobiological outcomes of ACEs, morphological and genomic protocols must be developed and validated which is this study’s focus. Paraffin embedding and microtome …
Evaluation Of Sleep Outcomes After Traumatic Brain Injury In Children Using Questionnaires And Actigraphy, 2024 Portland State University
Evaluation Of Sleep Outcomes After Traumatic Brain Injury In Children Using Questionnaires And Actigraphy, Connie Tran, Sydney Weese, Cydni Williams Md
Student Research Symposium
Traumatic brain injuries are the result of a sudden external blunt force to the brain and can result in long-term complications or death. In pediatrics, it is the leading cause of acute and chronic sleep wake disturbances, as well as cognitive deficits, which can lead to a reduction in the quality of life. These impairments can later result in lowered performance in work and school settings or decreased psychosocial function. Although there is sufficient evidence that traumatic brain injuries contribute to is that it is unknown whether or not sleep wake disturbances contribute to an increase in the mentioned cognitive …
Neuroscience Educational Interventions For Mental Health Management Within The Neurodiverse Population: A Working Model, 2024 Portland State University
Neuroscience Educational Interventions For Mental Health Management Within The Neurodiverse Population: A Working Model, Kadi Rae Smith, C.K. Miller, Bill Griesar, Jeff Leake
Student Research Symposium
Sociological and environmental factors such as economic disparity and cultural marginalization hinder access to educational and medical resources and must be taken into account to ensure accurate diagnoses, effective self-regulation and mental health management for neurodiverse individuals, and offset disparities in access to healthcare and education. Arbitrary attachment of stigma to traits commonly associated with neurodivergence perpetuate neuro-myths1 that have dire consequences when internalized, informing individuals’ development and sense of self. Neuroscience outreach done by NW Noggin is an active model for engaging communities with limited resources and a greater need for services to offset economic disparity. Integrated arts programming …
Understanding The Importance Of Social Emotional Learning In Children And The Link Between Mental Health, 2024 Portland State University
Understanding The Importance Of Social Emotional Learning In Children And The Link Between Mental Health, Lynette Marie Lubiak
Student Research Symposium
I will examine how very important it is to society to teach structured Social Emotional Learning (SEL) programs to children in school. It can bring mental wellbeing and the ability to have healthy relationships, non addictive behaviors and being able to emotionally regulate themselves. Since we have pushed on only academia and not SEL for our children, mental illness has skyrocketed. This problem started after the SEL part of school was taken out of schools and then the division between rich and poor became wider and wider as time went on. If we were to bring back SEL into school, …
Investigating The Antibacterial And Immunomodulatory Effects Of Resolvin D2 On Monocytes And Macrophages, 2024 Rowan University
Investigating The Antibacterial And Immunomodulatory Effects Of Resolvin D2 On Monocytes And Macrophages, Cristina Maria Padovani
Theses and Dissertations
In the late phase of sepsis, immunosuppression occurs, where the host is unable to clear the pre-existing infection and is susceptible to secondary infections. It is believed that the ideal treatments for sepsis should attenuate immunosuppression so that the host can get back to homeostasis. Specialized Pro-resolving Mediators (SPMs) are endogenously- produced fatty acids that resolve infectious inflammation without being immunosuppressive. We hypothesize that an SPM – Resolvin D2 (RvD2) – can augment exhausted macrophage function during the immunosuppressive phase of sepsis. We developed a two-hit model to establish macrophage exhaustion in vitro, and found that RvD2 increased NF-κB activity, …
Altered Sensitivity To Cocaine In Adolescent Spontaneously Hypertensive Rats, A Rodent Model Of Attention-Deficit/Hyperactivity Disorder, 2024 Trinity College
Altered Sensitivity To Cocaine In Adolescent Spontaneously Hypertensive Rats, A Rodent Model Of Attention-Deficit/Hyperactivity Disorder, Ingrid Schoenborn
Senior Theses and Projects
Adolescents with attention-deficit/hyperactivity disorder (ADHD) are at greater risk for psychostimulant abuse compared to those without ADHD. This may be due to alterations in the mesolimbocortical dopamine system; indeed, psychostimulant-induced dopamine release is greater in adult spontaneously hypertensive rats (SHRs; a rodent model of ADHD) compared to controls. Here, we sought to determine the extent to which neurobehavioral responses to cocaine are altered in adolescent SHRs. To begin to address this question, adolescent male and female SHRs and Sprague Dawley (SD; a reference strain) rats were first assessed for behavioural signs of ADHD, including inattention (Y-maze test) and hyperactivity (open-field …
Individual Differences In Age And Testosterone Are Uniquely Associated With Neural Oscillatory Activity Serving Verbal Working Memory In Children And Adolescents, 2024 University of Nebraska Medical Center
Individual Differences In Age And Testosterone Are Uniquely Associated With Neural Oscillatory Activity Serving Verbal Working Memory In Children And Adolescents, Abraham D. Killanin
Theses & Dissertations
During the sensitive period of adolescence, the human brain undergoes dynamic changes in structure and function resulting in vast executive function gains. Verbal working memory (VWM) is one executive function that serves as a foundation to language acquisition, reading, and learning. Many have examined the development of VWM in youth, but few have probed age-related changes in the underlying neural oscillatory dynamics, and none have examined testosterone-related changes. We recorded magnetoencephalography during a modified Sternberg VWM task in 82 youth participants aged 6 – 14 years old and collected salivary testosterone samples. Significant oscillatory responses were identified and imaged using …
How Does Schizophrenia Affect The Expression Of Alpha 7 Nicotinic Acetylcholine Receptors In The Brain?, 2024 Rowan University
How Does Schizophrenia Affect The Expression Of Alpha 7 Nicotinic Acetylcholine Receptors In The Brain?, Shruti Varshney, Nimish Acharya
Rowan-Virtua Research Day
Schizophrenia (SZ) is a psychiatric disorder with a pathophysiology that has not yet been fully understood. This mental illness is characterized by disruptions in cognition, social activity, affect, and perception, and affects approximately 0.085% of individuals worldwide. The Alpha 7 Nicotinic Acetylcholine Receptor (α7nAChR) has been connected to auditory function gating deficits. The purpose of this review is to understand the current literature in how the levels of α7nAChR expression and function are affected by SZ, information that could be used to develop therapies to modulate auditory hallucinations in patients with SZ. A literature search was conducted for peer-reviewed journal …
The Neuroprotective Role Of Lipoxin A4 In Reinstating Blood Brain Barrier Integrity In Neuroinflammatory Disease Processes, 2024 Rowan University
The Neuroprotective Role Of Lipoxin A4 In Reinstating Blood Brain Barrier Integrity In Neuroinflammatory Disease Processes, Minjal Patel, Nimish Acharya
Rowan-Virtua Research Day
Background: The blood-brain barrier (BBB), formed by the vascular endothelium, astrocytic foot processes, pericytes, is a highly selective barrier that is responsible for maintaining brain homeostasis and ultimately proper neuronal function. Disruption of the BBB, leading to increased BBB permeability, has been reported in several neurodegenerative diseases, including Alzheimer’s disease (AD) and traumatic brain injury (TBI).1 Loss of BBB integrity leads to the proliferation of pro-inflammatory cytokines, including TNFɑ, IL-1β, and IL-6.2 Moderate inflammation has a beneficial response in the system following an acute injury. However, prolonged inflammation has been known to perturb homeostasis and have …