Component Model Development Of Heat Exchangers, Expanders, And Control Valves For Autonomous Cryogenics Plant Cool-Down,
2025
Old Dominion University
Component Model Development Of Heat Exchangers, Expanders, And Control Valves For Autonomous Cryogenics Plant Cool-Down, William Harris Buhrig Iv
Mechanical & Aerospace Engineering Theses & Dissertations
The traditional method of cryogenic plant cool-down involves having continuous on-call staff to head into the office at any time to modify the existing multi-layered PID control systems if the on-call staff member detects a significant deviation from the cool-down plan. This thesis aims to outline an effective method for modeling the structure of systems with performance characteristics that deviate from design requirements and from ideal inlet-outlet correspondence, enabling the adjustment and modification of existing control structures across all Thomas Jefferson National Accelerator Facility (JLab) cryogenic refrigeration plants. Analytical Modeling and Gaussian Process Regression (GPR) are applied to model the …
Two Topics In Survival Analysis: Restricted Distance Covariance Test For Non-Proportional Hazard And A New Estimation For Dropout Rate,
2025
University of Arkansas-Fayetteville
Two Topics In Survival Analysis: Restricted Distance Covariance Test For Non-Proportional Hazard And A New Estimation For Dropout Rate, Ruizhe Yin
Graduate Theses and Dissertations
When treatment effects change over time, standard statistical methods, such as the log-rank test and the Cox proportional hazards model, may give misleading results. This dissertation presents the restricted distance covariance (rdcov) test, a nonparametric method that compares survival curves between groups within a chosen study period [0, τ] using right censored data. The statistic measures the dependence between pre-specified group labels and survival times using pairwise distances from Kaplan-Meier estimates. Our method does not rely on the proportional hazards assumption, and it equals zero only when survival functions are identical across groups. Thus, this test can be applied to …
Tradespace Exploration For Multiple Collaborative Vehicles,
2025
Clemson University
Tradespace Exploration For Multiple Collaborative Vehicles, Mrunal Deshmukh
All Theses
Modern military operations demand systems that adapt to uncertain, rapidly changing missions across diverse terrains. Traditional single-platform vehicle design is insufficient for such complexity. This research introduces a hierarchical tradespace exploration framework for designing and evaluating families of heterogeneous ground vehicles under a System-of-Systems (SoS) architecture. The framework treats vehicle design as a co-optimization problem, where a “parent” vehicle (e.g., a Squad Multipurpose Equipment Transport) coordinates specialized “child” vehicles for reconnaissance, amphibious tasks, terrain traversal, and stealth missions. Unlike conventional approaches that optimize vehicles individually, this study emphasizes collaborative performance, resource sharing, and adaptability at the family level. Central to …
Is Complexity Virtuous?,
2025
University of Denver
Is Complexity Virtuous?, Ryan Elmore, Jack Strauss
Business Information and Analytics: Faculty Scholarship
(Kelly et al., 2024) show that increasing complexity in linear models, with potentially thousands of predictors, is "virtuous". Their work contradicts the dogma of model selection, including the Principles of Parsimony and Occam's Razor. They find that when the number of predictors far exceeds the number of observations, the bias-variance trade-off breaks down, the variance declines, and the Sharpe ratio increases. In the context of ridge regression, we find that very high complexity coupled with large penalty terms (excessive shrinkage) generate forecasts that converge to a rolling window of past returns. For example, we show the past twelve-month moving average …
Benchmarking Dna Foundation Models For Genomic And Genetic Tasks,
2025
MD Anderson Cancer Center, Houston, TX
Benchmarking Dna Foundation Models For Genomic And Genetic Tasks, Haonan Feng, Lang Wu, Bingxin Zhao, Chad Huff, Jianjun Zhang, Jia Wu, Lifeng Lin, Peng Wei, Chong Wu
School of Medicine Faculty Publications
The rapid evolution of DNA foundation models promises to revolutionize genomics, yet comprehensive evaluations are lacking. Here, we present a comprehensive, unbiased benchmark of five models (DNABERT-2, Nucleotide Transformer V2, HyenaDNA, Caduceus-Ph, and GROVER) across diverse genomic and genetic tasks including sequence classification, gene expression prediction, variant effect quantification, and topologically associating domain (TAD) region recognition, using zero-shot embeddings. Our analysis reveals that mean token embedding consistently and significantly improves sequence classification performance, outperforming other pooling strategies. Model performance varies among tasks and datasets; while general purpose DNA foundation models showed competitive performance in pathogenic variant identification, they were less …
Improving Glycemic Control Among Indonesian Urban Adults: A Digital And Behavioral Extension Of The Information–Motivation–Behavioral Skills Model,
2025
Sekolah Tinggi Ilmu Kesehatan Gunung Sari, Makassar
Improving Glycemic Control Among Indonesian Urban Adults: A Digital And Behavioral Extension Of The Information–Motivation–Behavioral Skills Model, Imelda Appulembang
Kesmas
Management of type 2 diabetes mellitus (T2DM) in Indonesia continues to face challenges due to behavioral, informational, and technological gaps among patients. This study analyzed the influence of self-regulatory competence and information, motivation, family support, and digital health literacy on glycemic control behavior. A cross-sectional survey was conducted from February to April 2025 among 587 adults aged >30 years with T2DM enrolled in the Chronic Disease Management Program at primary health care in six major cities: Jakarta, Surabaya, Yogyakarta, Medan, Makassar, and Banjarmasin. Data were collected through structured questionnaires and analyzed using partial least squares structural equation modeling. The findings …
Tannin Supplementation Alters Foraging Behavior And Spatial Distribution In Beef Cattle,
2025
Utah State University
Tannin Supplementation Alters Foraging Behavior And Spatial Distribution In Beef Cattle, Bashiri Iddy Muzzo, R. Douglas Ramsey, Kelvyn Bladen, Juan J. Villalba
Wildland Resources Student Research
Beef production on chemically uniform grass monocultures can limit nutrient synchrony and contribute to uneven pasture use. We evaluated whether supplementing tannins with bioactive plant secondary compounds improves foraging dynamics and landscape use by beef cattle grazing a meadow bromegrass monoculture in ways aligned with rangeland sustainability. Twenty-four Angus cow–calf pairs were allocated to six 3.6-ha paddocks (four pairs/paddock), randomly assigned to Control (Ctrl; n = 3) or Tannin treatment (TT; n = 3). Animals received 1 kg/cow/day of DDGs, with TT receiving an added 0.4% tannins (2:1 condensed:hydrolyzable). Grazing occurred during four 15-day periods (July– September) across two years. …
Field Validation Of Multiple Species Distribution Models Shows Variation In Performance For Predicting Aedes Albopictus Distributions At The Invasion Edge,
2025
University of South Carolina
Field Validation Of Multiple Species Distribution Models Shows Variation In Performance For Predicting Aedes Albopictus Distributions At The Invasion Edge, Anna V. Shattuck, Brandon D. Hollingsworth Ph.D., Jared Skrotzki, Scott R. Campbell, Christopher L. Romano, Courtney C. Murdock
Faculty Publications
Background
Climate and land use changes have resulted in range expansion of many species. In this shifting disease landscape, it is important to leverage tools that can predict the distributions of invading vectors to target surveillance and control efforts and identify at-risk populations. Species distribution models (SDMs) are used to predict ranges of invasive species; however, invasive species often violate assumptions of equilibrium and niche conservatism. Moreover, these studies are rarely validated using independent data.
Methods
We use long-term surveillance data for Aedes albopictus, a highly invasive mosquito capable of transmitting several arboviruses, at its range edge to evaluate a …
Exploring The Impact Of Statistics Course Modality On Student Learning: A Mixed Methods Approach,
2025
University of Denver
Exploring The Impact Of Statistics Course Modality On Student Learning: A Mixed Methods Approach, Becky Kelleman
Electronic Theses and Dissertations
The importance of statistical literacy has become increasingly evident, as individuals grapple with interpreting statistics to inform critical decisions. Despite the recognized significance of statistical literacy, challenges persist in both educators’ and students’ efforts to navigate the complexities of statistics education. The purpose of this study is to explore the impact of different course modalities on undergraduate students’ academic performance in introductory statistics courses. Using Social Cognitive Theory (SCT) as a theoretical framework, this research aims to shed light on the complex dynamics influencing statistical literacy attainment. By addressing gaps and inconsistencies in the current literature, this study seeks to …
On Some Algebraic And Dynamical Aspects Of Families Of Polynomials,
2025
Indian Statistical Institute
On Some Algebraic And Dynamical Aspects Of Families Of Polynomials, Prabhakar Ratipal Yadav
Doctoral Theses
This thesis investigates several arithmetic and algebraic properties of polynomials, with a particular emphasis on irreducibility, monogenity, and the behaviour of iterated polynomial sequences. We first study truncated binomial polynomials over the rationals and establish new affirmative results concerning their irreducibility. A substantial part of the work develops a detailed analysis of Newton polygons under polynomial composition. These structural insights yield broad applications, including criteria for stability and eventual stability of large families of polynomials, as well as precise information about the degrees and number of irreducible factors appearing in their iterates. These ideas further connect to questions about ramification …
The Odds Don’T Lie: Mathematical Reasoning And Societal Ignorance In Don’T Look Up,
2025
West Morris Central High School
The Odds Don’T Lie: Mathematical Reasoning And Societal Ignorance In Don’T Look Up, Nysa Vedwan, Shane Carey
LASER Journal
In Adam McKay’s 2021 satirical sci-fi movie Don’t Look Up, two astronomers discover a comet heading directly toward Earth. Despite overwhelming evidence and near-certainty of global extinction, their warnings are ignored and ridiculed. This paper discusses the mathematical and scientific foundations of the movie’s social and political reception, and specifically focuses on orbital prediction and probabilistic modeling as they relate to public understanding of risk. This paper shows how data is often undermined by political and social dynamics, by connecting the fictional events of the movie with real-world crises like the COVID-19 pandemic and the climate emergency. In Don’t Look …
Spatially Mapped Statewide Estimated Potential Evapotranspiration Using An Efficient Surface Interpolation Method: A Case Study Of South Carolina,
2025
IESA, University of North Georgia
Spatially Mapped Statewide Estimated Potential Evapotranspiration Using An Efficient Surface Interpolation Method: A Case Study Of South Carolina, Sudhanshu S. Panda, Devendra M. Amatya, Ka Kit Liu, Augustine Muwamba, Timothy J. Callahan
Journal of South Carolina Water Resources
Potential evapotranspiration (PET) exhibits substantial spatial and temporal variability across large landscapes, necessitating site-specific estimation for accurate environmental and water resource assessments. However, obtaining PET or ET data for specific locations across an entire state remains challenging due to the limited number of weather stations and associated environmental datasets. This study aimed to develop an automated geospatial modeling framework to map PET distribution across South Carolina, USA, using PET estimated by the temperature-based Hargreaves–Samani (H–S) method with daily weather data from 59 NOAA stations. Because the accuracy of spatial interpolation depends on both the target variable and the desired spatial …
Latent Classification Of Time-Dependent Transition Rates In Longitudinal Binary Outcome Data,
2025
LSU Health Sciences Center - New Orleans
Latent Classification Of Time-Dependent Transition Rates In Longitudinal Binary Outcome Data, Joonha Chang, Wenyaw Chan
School of Public Health Faculty Publications
Continuous-time Markov chain (CTMC) models and latent classification methods are commonly used to analyze longitudinal categorical outcomes in medical research. While CTMC models are popular for their simplicity and effectiveness, their assumption of constant transition rates presents limitations in capturing dynamic behaviors. To address this, non-homogeneous continuous-time Markov chains (NH-CTMCs) have been developed, incorporating time-varying transition rates to enhance model flexibility. In this study, we leverage closed-form transition probabilities for a fully ergodic two-state NH-CTMC model and propose a latent class clustering approach to identify heterogeneous transition rate patterns within the population. We emphasize the potential advantages of these models …
Explainable Post-Operative Patients Recovery Prediction Following Elective Brain Tumor Resection: A Precision Medicine Approach,
2025
Johns Hopkins University
Explainable Post-Operative Patients Recovery Prediction Following Elective Brain Tumor Resection: A Precision Medicine Approach, Eleanor Belkin
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
[Kyda] Biologically Grounded Surrogate-Driven Parameter Inference For Sparsely Observed Dynamical Systems,
2025
Johns Hopkins University
[Kyda] Biologically Grounded Surrogate-Driven Parameter Inference For Sparsely Observed Dynamical Systems, Joshua C. Macdonald
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
[Project Insight] Spatio-Temporal Analysis Of Domestic Violence In Puerto Rico,
2025
University of Kansas, Lawrence, Kansas, USA
[Project Insight] Spatio-Temporal Analysis Of Domestic Violence In Puerto Rico, Phyllis Muniu
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Mentoring First-Year Stem Students Through Collaborative Research In The Haynes Scholars Program,
2025
James Madison University
Mentoring First-Year Stem Students Through Collaborative Research In The Haynes Scholars Program, Alex Capaldi, Laura Tipton
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
[Lele] Incorporating Physiological Constraints In Estimates Of Post-Prandial Insulin Secretion Rate,
2025
University of Maryland - Baltimore County
[Lele] Incorporating Physiological Constraints In Estimates Of Post-Prandial Insulin Secretion Rate, Justin K. Garrish, Christine L. Chan, Douglas Nychka, Cecilia Diniz Behn
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Correlation With Car Density In Urban Environments And Its Influence On Chronic Obstructive Pulmonary Disease (Copd) Rates In The United States,
2025
Inter American University of Puerto Rico - Bayamon
Correlation With Car Density In Urban Environments And Its Influence On Chronic Obstructive Pulmonary Disease (Copd) Rates In The United States, Daniel Barreiro-Torres, Kedai Cheng
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Statistical Challenges And Simulation Results For Pilot Clinical Trials,
2025
University of South Florida
Statistical Challenges And Simulation Results For Pilot Clinical Trials, Weiliang Cen
USF Tampa Graduate Theses and Dissertations
Background: The effect size estimated from a pilot trial is often an inaccurate reflection of the true effect size observed in a large trial, leading to either underestimation or overestimation. Published data suggest that effect sizes from large trials are typically smaller than those reported in their corresponding pilot trials. To address this discrepancy, conservative or discount adjustment methods are widely recommended to modify pilot trial effect sizes when calculating sample sizes, thereby maintaining adequate statistical power. This study aims to assess effect sizes from both pilot and large trials and to evaluate the performance of existing adjustment methods.
Methods: …
