Statistics and Probability Commons^™

Detection And Relative Quantitation Of Changes In Gene Expression Of Hippo Proteins In Doxorubicin-Exposed Human Cells By Rt-Qpcr, Lillian Fleisher, Tricia Domingo, Christopher So, Stephen Lee

Annual Research Symposium

No abstract provided.

Action Plan: Gym Cleanliness At The Jaeger Center, Blair A. O'Connor

CAFE Symposium 2024

I have created an action plan to assess current patrons' satisfaction with the cleaning materials provided at the Gettysburg College Jaeger Center, and increase the amount or variety if the need is there. Due to a combination of behaviors and bacteria in the Jaeger Center, gym users are at risk of contracting infections. The objective of this plan is for gym users to feel more empowered and safe in their environment. While there may be individuals who feel like increased disinfecting efforts and supplies are not necessary at the Jaeger Center, what may not be a concern for one person …

Predicting Crop Yield Using Remote Sensing Data, Mary Row, Jung-Han Kimn, Hossein Moradi

SDSU Data Science Symposium

Accurate crop yield predictions can help farmers make adjustments or changes in their farming practices to optimize their harvest. Remote sensing data is an inexpensive approach to collecting massive amounts of data that could be utilized for predicting crop yield. This study employed linear regression and spatial linear models were used to predict soybean yield with data from Landsat 8 OLI. Each model was built using only spectral bands of the satellite, only vegetation indices, and both spectral bands and vegetation indices. All analysis was based on data collected from two fields in South Dakota from the 2019 and 2021 …

Principal Component Analysis With Application To Credit Card Data, Eleanor Cain, Semhar Michael, Gary Hatfield

SDSU Data Science Symposium

Principal Component Analysis (PCA) is a type of dimension reduction technique used in data analysis to process the data before making a model. In general, dimension reduction allows analysts to make conclusions about large data sets by reducing the number of variables while retaining as much information as possible. Using the numerical variables from a data set, PCA aims to compute a smaller set of uncorrelated variables, called principal components, that account for a majority of the variability from the data. The purpose of this poster is to understand PCA as well as perform PCA on a large sample credit …

Session 6: Model-Based Clustering Analysis On The Spatial-Temporal And Intensity Patterns Of Tornadoes, Yana Melnykov, Yingying Zhang, Rong Zheng

SDSU Data Science Symposium

Tornadoes are one of the nature’s most violent windstorms that can occur all over the world except Antarctica. Previous scientific efforts were spent on studying this nature hazard from facets such as: genesis, dynamics, detection, forecasting, warning, measuring, and assessing. While we want to model the tornado datasets by using modern sophisticated statistical and computational techniques. The goal of the paper is developing novel finite mixture models and performing clustering analysis on the spatial-temporal and intensity patterns of the tornadoes. To analyze the tornado dataset, we firstly try a Gaussian distribution with the mean vector and variance-covariance matrix represented as …

Session 6: The Size-Biased Lognormal Mixture With The Entropy Regularized Algorithm, Tatjana Miljkovic, Taehan Bae

SDSU Data Science Symposium

A size-biased left-truncated Lognormal (SB-ltLN) mixture is proposed as a robust alternative to the Erlang mixture for modeling left-truncated insurance losses with a heavy tail. The weak denseness property of the weighted Lognormal mixture is studied along with the tail behavior. Explicit analytical solutions are derived for moments and Tail Value at Risk based on the proposed model. An extension of the regularized expectation–maximization (REM) algorithm with Shannon's entropy weights (ewREM) is introduced for parameter estimation and variability assessment. The left-truncated internal fraud data set from the Operational Riskdata eXchange is used to illustrate applications of the proposed model. Finally, …

A Causal Inference Approach For Spike Train Interactions, Zach Saccomano

Dissertations, Theses, and Capstone Projects

Since the 1960s, neuroscientists have worked on the problem of estimating synaptic properties, such as connectivity and strength, from simultaneously recorded spike trains. Recent years have seen renewed interest in the problem coinciding with rapid advances in experimental technologies, including an approximate exponential increase in the number of neurons that can be recorded in parallel and perturbation techniques such as optogenetics that can be used to calibrate and validate causal hypotheses about functional connectivity. This thesis presents a mathematical examination of synaptic inference from two perspectives: (1) using in vivo data and biophysical models, we ask in what cases the …

Model Selection Through Cross-Validation For Supervised Learning Tasks With Manifold Data, Derek Brown

The Journal of Purdue Undergraduate Research

No abstract provided.

Sensitivity Analysis Of Prior Distributions In Regression Model Estimation, Ayoade I Adewole, Oluwatoyin K. Bodunwa

Al-Bahir Journal for Engineering and Pure Sciences

Bayesian inferences depend solely on specification and accuracy of likelihoods and prior distributions of the observed data. The research delved into Bayesian estimation method of regression models to reduce the impact of some of the problems, posed by convectional method of estimating regression models, such as handling complex models, availability of small sample sizes and inclusion of background information in the estimation procedure. Posterior distributions are based on prior distributions and the data accuracy, which is the fundamental principles of Bayesian statistics to produce accurate final model estimates. Sensitivity analysis is an essential part of mathematical model validation in obtaining …

Statistical Consulting In Academia: A Review, Ke Xiao

Major Papers

This paper reviews the state of statistical consulting in academia by performing a literature review on this topic in chapters 1 and 2. Chapter 1 overviews general aspects of statistical consulting and types of centers that conduct such services in academia. In Chapter 2 we summarise the literature about the common logistics and processes for conducting statistical consulting in academia. In Chapters 3 and 4, we analyze data on statistical consulting centers for the largest 100 universities in the USA. We also review the literature on the future of statistical consulting in academia in the era of big data and …

Time Scale Theory On Stability Of Explicit And Implicit Discrete Epidemic Models: Applications To Swine Flu Outbreak, Gülşah Yeni, Elvan Akın, Naveen K. Vaidya

Mathematics and Statistics Faculty Research & Creative Works

Time scales theory has been in use since the 1980s with many applications. Only very recently, it has been used to describe within-host and between-hosts dynamics of infectious diseases. In this study, we present explicit and implicit discrete epidemic models motivated by the time scales modeling approach. We use these models to formulate the basic reproduction number, which determines whether an outbreak occurs, or the disease dies out. We discuss the stability of the disease-free and endemic equilibrium points using the linearization method and Lyapunov function. Furthermore, we apply our models to swine flu outbreak data to demonstrate that the …

Formulating An Efficient Statistical Test Using The Goodness Of Fit Approach With Applications To Real-Life Data, S. A. Qaid, S. E. Abo Youssef Prof., Mahmoud Mansour

Basic Science Engineering

Statistical tests are very important for researchers to make decisions. In particular, when the tests are non-parametric, they are of greater importance because they can be applied to a wide range of data sets regardless of knowing the distribution of these data. Researchers are therefore racing to obtain efficient tests for making good decisions based on the results of these tests. In this study, NBU (2)L was used based on the goodness of fit approach to present an efficient statistical test. The efficiency of the proposed test was computed, and the results were compared to those of other tests. Critical …

On A Multivalued Prescribed Mean Curvature Problem And Inclusions Defined On Dual Spaces, Vy Khoi Le

Mathematics and Statistics Faculty Research & Creative Works

This article addresses two main objectives. First, it establishes a functional analytic framework and presents existence results for a quasilinear inclusion describing a prescribed mean curvature problem with homogeneous Dirichlet boundary conditions, involving a multivalued lower order term. The formulation of the problem is done in the space of functions with bounded variation. The second objective is to introduce a general existence theory for inclusions defined on nonreflexive Banach spaces, which is specifically applicable to the aforementioned prescribed mean curvature problem. This problem can be formulated as a multivalued variational inequality in the space of functions with bounded variation, which, …

Tropical Fish Study In Tahiti, French Polynesia, Miranda Brainard, Caitlyn Swango, Paityn Houglan, Richard Londraville

Williams Honors College, Honors Research Projects

In May of 2023, I embarked on an exciting research journey to Moorea, French Polynesia, alongside fellow students and faculty members from the University of Akron and Syracuse University. This expedition was part of the university-sponsored Tropical Vertebrate Biology course, where we delved into the exploration of various tropical species inhabiting the island, including sea urchins, geckos, and my primary focus, the blackspotted rockskipper.

My research team, composed of my co-authors and me, was particularly intrigued by the unique refuge-seeking behavior displayed by blackspotted rockskippers. These amphibious fish are renowned for their remarkable ability to inhabit tide pools and rocky …

Regional Price Index 2023, Department Of Primary Industries And Regional Development, Western Australia

Statistics

The 2023 Regional Price Index (RPI) is the eleventh State Government Index contrasting the cost of a common basket of goods and services at a number of regional locations to the Perth metropolitan region. The RPI is used as the basis for the construction of the public sector district allowance, and by the private sector when considering remuneration packages for remotely located staff.

The RPI provides an insight into differences in regional consumer costs. The 2023 RPI basket of 185 goods and services was priced in 39 regional centres around Western Australia.

The 2023 RPI results show that, overall, prices …

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen

Theses and Dissertations (Comprehensive)

The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …

Measuring The Performance Of Sdgs In Provincial Level Using Regional Sustainable Development Index, Nurafiza Thamrin, Ika Yuni Wulansari, Puguh Bodro Irawan

Journal of Environmental Science and Sustainable Development

Measuring the national and sub-national progress in achieving such globally adopted development agendas as Sustainable Development Goals (SDGs) is particularly challenging due to data availability and compatibility of indicators to measure SDGs, especially in Indonesia. This paper attempts to measure the performance of sustainable development at the regional level in Indonesia by newly constructing a multidimensional composite index called the Regional Sustainable Development Index (RSDI). RSDI comprises four dimensions, covering comprehensive economic, social, environmental, and governance indicators. By applying factor analysis, the paper assesses the uncertainty of RSDI and the sensitivity of its composing indicators, then further investigates the relationship …

Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia

Journal of Nonprofit Innovation

Urban farming can enhance the lives of communities and help reduce food scarcity. This paper presents a conceptual prototype of an efficient urban farming community that can be scaled for a single apartment building or an entire community across all global geoeconomics regions, including densely populated cities and rural, developing towns and communities. When deployed in coordination with smart crop choices, local farm support, and efficient transportation then the result isn’t just sustainability, but also increasing fresh produce accessibility, optimizing nutritional value, eliminating the use of ‘forever chemicals’, reducing transportation costs, and fostering global environmental benefits.

Imagine Doris, who is …

Cabozantinib Plus Atezolizumab In Previously Untreated Advanced Hepatocellular Carcinoma And Previously Treated Gastric Cancer And Gastroesophageal Junction Adenocarcinoma: Results From Two Expansion Cohorts Of A Multicentre, Open-Label, Phase 1b Trial (Cosmic-021)., Daneng Li, Yohann Loriot, Adam Burgoyne, James Cleary, Armando Santoro, Daniel Lin, Santiago Ponce Aix, Ignacio Garrido-Laguna, Ramu Sudhagoni, Xiang Guo, Svetlana Andrianova, Scott Paulson

Kimmel Cancer Center Faculty Papers

BACKGROUND: Cabozantinib is approved for previously treated advanced hepatocellular carcinoma (aHCC) and has been investigated in gastric cancer (GC) and gastroesophageal junction adenocarcinoma (GEJ). Atezolizumab plus bevacizumab is approved for unresectable or metastatic HCC untreated with prior systemic therapy. We evaluated efficacy and safety of cabozantinib plus atezolizumab in aHCC previously untreated with systemic anticancer therapy or previously treated GC/GEJ.

METHODS: COSMIC-021 (ClinicalTrials.gov, NCT03170960) is an open-label, phase 1b study in solid tumours with a dose-escalation stage followed by tumour-specific expansion cohorts, including aHCC (cohort 14) and GC/GEJ (cohort 15). Eligible patients were aged ≥18 years with measurable locally advanced, …

Challenges And Countermeasures For Treatment And Remediation Of Contaminated Mega-Sites In China, Xiaoyong Liao, Yixuan Hou, You Li, Tianyi Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The treatment and remediation of pollution at contaminated mega-sites poses a significant challenge in the environmental science both domestically and internationally. Contaminated mega-sites are characterized by their widespread impact, multiple types of pollutants, and significant ecological and environmental threats. The environmental behavior cognition and efficient remediation at contaminated mega-sites face enormous challenges, among which key technological issues such as the formation mechanism of soil and groundwater pollution, accurate identification of pollution sources, and intelligent decision-making optimization urgently need to be solved. In China, contaminated mega-sites are concentrated in economically developed regions such as Beijing-Tianjin-Hebei, the Yangtze River Economic Belt, and …