Latent Classification Of Time-Dependent Transition Rates In Longitudinal Binary Outcome Data,
2025
LSU Health Sciences Center - New Orleans
Latent Classification Of Time-Dependent Transition Rates In Longitudinal Binary Outcome Data, Joonha Chang, Wenyaw Chan
School of Public Health Faculty Publications
Continuous-time Markov chain (CTMC) models and latent classification methods are commonly used to analyze longitudinal categorical outcomes in medical research. While CTMC models are popular for their simplicity and effectiveness, their assumption of constant transition rates presents limitations in capturing dynamic behaviors. To address this, non-homogeneous continuous-time Markov chains (NH-CTMCs) have been developed, incorporating time-varying transition rates to enhance model flexibility. In this study, we leverage closed-form transition probabilities for a fully ergodic two-state NH-CTMC model and propose a latent class clustering approach to identify heterogeneous transition rate patterns within the population. We emphasize the potential advantages of these models …
Explainable Post-Operative Patients Recovery Prediction Following Elective Brain Tumor Resection: A Precision Medicine Approach,
2025
Johns Hopkins University
Explainable Post-Operative Patients Recovery Prediction Following Elective Brain Tumor Resection: A Precision Medicine Approach, Eleanor Belkin
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
[Kyda] Biologically Grounded Surrogate-Driven Parameter Inference For Sparsely Observed Dynamical Systems,
2025
Johns Hopkins University
[Kyda] Biologically Grounded Surrogate-Driven Parameter Inference For Sparsely Observed Dynamical Systems, Joshua C. Macdonald
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
[Project Insight] Spatio-Temporal Analysis Of Domestic Violence In Puerto Rico,
2025
University of Kansas, Lawrence, Kansas, USA
[Project Insight] Spatio-Temporal Analysis Of Domestic Violence In Puerto Rico, Phyllis Muniu
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Mentoring First-Year Stem Students Through Collaborative Research In The Haynes Scholars Program,
2025
James Madison University
Mentoring First-Year Stem Students Through Collaborative Research In The Haynes Scholars Program, Alex Capaldi, Laura Tipton
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
[Lele] Incorporating Physiological Constraints In Estimates Of Post-Prandial Insulin Secretion Rate,
2025
University of Maryland - Baltimore County
[Lele] Incorporating Physiological Constraints In Estimates Of Post-Prandial Insulin Secretion Rate, Justin K. Garrish, Christine L. Chan, Douglas Nychka, Cecilia Diniz Behn
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Correlation With Car Density In Urban Environments And Its Influence On Chronic Obstructive Pulmonary Disease (Copd) Rates In The United States,
2025
Inter American University of Puerto Rico - Bayamon
Correlation With Car Density In Urban Environments And Its Influence On Chronic Obstructive Pulmonary Disease (Copd) Rates In The United States, Daniel Barreiro-Torres, Kedai Cheng
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Statistical Challenges And Simulation Results For Pilot Clinical Trials,
2025
University of South Florida
Statistical Challenges And Simulation Results For Pilot Clinical Trials, Weiliang Cen
USF Tampa Graduate Theses and Dissertations
Background: The effect size estimated from a pilot trial is often an inaccurate reflection of the true effect size observed in a large trial, leading to either underestimation or overestimation. Published data suggest that effect sizes from large trials are typically smaller than those reported in their corresponding pilot trials. To address this discrepancy, conservative or discount adjustment methods are widely recommended to modify pilot trial effect sizes when calculating sample sizes, thereby maintaining adequate statistical power. This study aims to assess effect sizes from both pilot and large trials and to evaluate the performance of existing adjustment methods.
Methods: …
Circulating Levels Of Insulin-Like Growth Factor I (Igf-I) And Risk Ofmultiple Myeloma: An Observational And Mendelian Randomisation Study,
2025
University of South Carolina
Circulating Levels Of Insulin-Like Growth Factor I (Igf-I) And Risk Ofmultiple Myeloma: An Observational And Mendelian Randomisation Study, Yolanda Benavente, Sara Hermosa, Nikos Papadimitriou, Alyssa I. Clay-Gilmour Ph.D., Elizabeth E. Brown, Jonathan N. Hofmann, Nathaniel Rothman, Qing Lan, Sonja I. Berndt, Demetrius Albanes, Mark Purdue, Mitchell J. Machiela, Stephen J. Chanock, Parveen Bhatti, Wendy Cozen, Aaron Norman, Susan L. Slager, James R. Cerhan, Vincent Rajkumar, Shaji J. Kumar, Et. Al.
Faculty Publications
Evidence for an association between insulin-like growth factors (IGF) and multiple myeloma (MM) is inconsistent. We examined total IGF-I concentrations and risk of MM by combining baseline serological data among UK Biobank participants (n = 444 187; 732 incident MM) with a two-sample Mendelian randomisation (MR) analysis using identified genetic variants associated with circulating total IGF-I and IGF-binding protein 3 (IGFBP-3) in the InterLymph consortium (2434 MM and their 2567 controls). Finally, additional lymphoid neoplasm (LN) subtypes were included for comparison with the main hypothesis. Circulating IGF-I level was positively associated with MM risk Hazard ratio-HR-per one standard deviation-SD-increase …
Network Construction Using Sparse Gaussian Graphical Model Based On Gwas Summary Statistics,
2025
Michigan Technological University
Network Construction Using Sparse Gaussian Graphical Model Based On Gwas Summary Statistics, Megh Subedi, Xuewei Cao, Byung-Jun Kim, Qiuying Sha
Michigan Tech Publications
In genome-wide association studies (GWAS), thousands of genetic variants are tested to identify their associations with a phenotype. GWAS have identified many strongly associated genetic variants with phenotypes and have greatly enhanced our understanding of the genetic architecture of complex phenotypes and diseases. Joint analysis of multiple phenotypes can increase the overall statistical power to detect genetic associations and allows for the identification of pleiotropic loci. A phenotype-phenotype network (PPN) represents phenotypes as nodes and the relationships between them as edges, which allows for the visualization of complex relationships between phenotypes, making it easier to identify clusters and helps us …
Perspectives On Firearm Storage Conversations: Summary Of Health Care Provider Interviews And Parent Focus Group,
2025
University of Southern Maine, Catherine Cutler Institute
Perspectives On Firearm Storage Conversations: Summary Of Health Care Provider Interviews And Parent Focus Group, Rachel M. Gallo Mph
Publications
This report summarizes perspectives from Maine parents who own firearms and health care providers on safe firearm storage and related conversations in health care settings. Through interviews and a parent focus group, the project explored how firearms are stored, what influences storage decisions, and how families and providers feel about discussing firearm safety. Parents emphasized the importance of responsible ownership, education, and individualized storage solutions, while identifying cost as a key barrier to safer storage options. Many health care providers expressed interest in addressing firearm safety but cited limited time, lack of training, and concerns about patient trust as challenges. …
‘Earth System Engineers’ And The Cumulative Impact Of Organisms In Deep Time,
2025
Swarthmore College
‘Earth System Engineers’ And The Cumulative Impact Of Organisms In Deep Time, S. A. F. Darroch, M. M. Casey, A. T. Cribb, A. E. Bates, M. E. Clapham, D. L. Contreras, M. Craffey, I. A. P. Duijnstee, W. Gearty, N. J. Gotelli, M. J. Hamilton, R. F. Hayes, P. M. Hull, D. E. Ibarra, V. A. Korasidis, J. Lee, C. V. Looy, T. R. Lyson, B. Muddiman, P. D. Roopnarine, A. B. Shupinski, F. A. Smith, A. L. Stigall, C. P. Tomé, K. A. Turk, A. Villaseñor, P. J. Wagner, Steve C. Wang
Mathematics & Statistics Faculty Works
Understanding the role of humans as ‘ecosystem engineers’ requires a deep-time perspective rooted in evolutionary history and the fossil record. However, no conceptual framework exists for studying the rise of ecosystem engineering in deep time, requiring us to consider effects that fall outside the scope of traditional definitions. Here, we present a new framework applicable to both modern and ancient engineering-type effects. We propose a new term – ‘Earth system engineering’ – to describe biological processes that alter the structure and function of planetary spheres, and which combines core tenets of ecosystem engineering, niche construction, and legacy effects. We illustrate …
How Fair Workweek Laws Affect Labor Markets: A New York City Case Study,
2025
U.S. Naval Academy
How Fair Workweek Laws Affect Labor Markets: A New York City Case Study, Joseph Pickens, Aaron Sojourner
Employment Research Newsletter
No abstract provided.
Adverse Childhood Experiences, Positive Childhood Experiences, And Digital Media Use Among Children And Adolescents In The United States,
2025
University of South Carolina
Adverse Childhood Experiences, Positive Childhood Experiences, And Digital Media Use Among Children And Adolescents In The United States, Elizabeth L. Crouch, Emma Boswell, Monique J. Brown Ph.D., Kevin J. Bennett
Publications
No abstract provided.
How Fair Workweek Laws Affect Labor Markets: A New York City Case Study,
2025
U.S. Naval Academy
How Fair Workweek Laws Affect Labor Markets: A New York City Case Study, Joseph Pickens, Aaron Sojourner
Upjohn Institute Policy and Research Briefs
No abstract provided.
Teaching Statistical Literacy Through An Excel Class Project,
2025
Lynn University
Teaching Statistical Literacy Through An Excel Class Project, Patricia Berchiolli, Omar Babun Codorniu
Faculty and Staff Publications & Presentations
Lynn University’s core curriculum, The Dialogues, enables students to develop critical thinking, communication, and innovation skills. As part of this curriculum, Introductory Statistics introduces students to key statistical concepts while showing how they can be applied in real-world situations using Excel. The highlight of the course is the Statistics Excel Project, where students create their own dataset with a mix of quantitative and qualitative variables. To keep the focus on learning statistical techniques rather than data collection, students use Excel’s random number generator for quantitative data, which also avoids the need for IRB approval. From there, they calculate statistical measures, …
The Effect Of Renewable Energy Consumption, Economic Growth, And Energy Use On Co₂ Emissions In Indonesia: An Ardl Analysis,
2025
Brawijaya University,Malang, Jawa Timur, Indonesia
The Effect Of Renewable Energy Consumption, Economic Growth, And Energy Use On Co₂ Emissions In Indonesia: An Ardl Analysis, Raihan Ahmad Mustofa, Mariam Kamila, Rininta Nurrachmi, Syifa Shafnastiara
Jurnal Kebijakan Ekonomi
Abstract This study examines the dynamic relationship between renewable energy consumption, total energy use, economic growth, and CO₂ emissions in Indonesia over the period 1990–2021 using an ARDL approach. The results show a stable long-run relationship with quick adjustment after shocks. In the long run, energy consumption is associated with higher CO₂ emissions, reflecting the continued dominance of fossil fuels. Renewable energy helps reduce emissions in the short term, but its long-term impact remains statistically insignificant. GDP does not show a significant effect, suggesting that meaningful decarbonization will require a more intensive shift in the energy mix.
Keywords: ARDL, renewable …
A Review Of Research And Practices On Teaching Data Visualizations For Blind And Visually Impaired Students,
2025
Smith College
A Review Of Research And Practices On Teaching Data Visualizations For Blind And Visually Impaired Students, Shiya Cao
Statistical and Data Sciences: Faculty Publications
Around 36 million people in the world are blind and an additional 217 million have moderate to severe vision impairment. In higher education, four percent of 54,204 undergraduates who participated in the 2022 American College Health Association survey reported to be blind or have low vision. Those students frequently do not have access to data visualizations we generally teach and use in postsecondary statistics and data science classes. The design of those visualizations is premised on implicit assumptions about the user’s visual ability. Making data visualizations accessible to blind and visually impaired (BVI) people would help improve equity in higher …
Engr 597: Special Projects In Engineering Science - Data Analytics,
2025
University of Mississippi
Engr 597: Special Projects In Engineering Science - Data Analytics, Ali Behnood Ph.D., P.E., M., Asce
GMAS Course Syllabi
No abstract provided.
Smarter Disease Detection From Electronic Health Record Data: An End-To-End Ai-Augmented Pipeline For Computable Phenotyping,
2025
Southern Methodist University
Smarter Disease Detection From Electronic Health Record Data: An End-To-End Ai-Augmented Pipeline For Computable Phenotyping, Dylan Owens
Statistical Science Theses and Dissertations
Electronic Health Records (EHR) contain a wealth of structured and unstructured patient data that can be leveraged for computable phenotyping, the process of algorithmically identifying patient cohorts with specific diseases or conditions. Traditional rule-based phenotyping approaches, while interpretable, often struggle with scalability, portability across institutions, and effective use of unstructured clinical narratives. Recent advances in large language models (LLMs) present new opportunities for synthesizing complex free-text information into concise, clinically meaningful representations. However, integrating LLMs into phenotyping workflows requires careful design to maintain transparency, interpretability, and measurable uncertainty—features essential for clinical adoption and downstream applications such as decision support.
We …
