Biological Psychology Commons^™

Are Caffeine’S Effects On Neuronal Calcium Levels Due To The Caffeine Metabolite, Paraxanthine?, Kendra Jean Hartsuyker

Cal Poly Humboldt theses and projects

Caffeine has diverse effects on neurons including, potentially, protection against Parkinson’s-related neurodegeneration. Caffeine may protect neurons from damage by limiting mitochondrial membrane permeability through a calcium-dependent mechanism. This study was a first step investigating calcium’s role in caffeine neuroprotection in vivo using zebrafish larvae. Elavl3:GCaMP6s zebrafish, which express a genetically encoded fluorescent calcium indicator protein in most CNS neurons, received caffeine (0, 50, 125, 250 µM, bath applied) in an ascending dose series during fluorescence calcium imaging of a central catecholaminergic nucleus (a proposed zebrafish homolog of the locus coeruleus, a structure affected in Parkinson’s disease). Parallel experiments tested effects …

Restoration Of Attentional Deficits After Concussion, Katharine B. Earle

Cal Poly Humboldt theses and projects

Difficulties with concentration and attention are among the most prevalent symptoms experienced after concussion. Rest has been the most common form of recovery from concussion; however, new research is suggesting mild mental exertion to be an effective aid in recovery. Drawing from Attention Restoration Theory, this study evaluated the idea that cognitive engagement with natural environments can mitigate post-concussion directed-attention deficits. A between subjects repeated measures design was used to test directed-attention after video exposure to restorative/nature and nonrestorative/city environments. Measures of mood, connectedness to environment, and symptomology scores were also collected. No meaningful difference between exposure type was found …

An Investigation Of The Relations Between Stress And Prospective Memory, Brandon T. Stewart

Graduate Student Theses, Dissertations, & Professional Papers

Prospective memory (PM) is a future-oriented memory system that entails “remembering to remember” intentions, or to perform actions in the future. People spend significant portions of their day-to-day lives forming and acting on intentions, and the ability to successfully generate, retain, and complete these intentions has important implications for one’s daily functioning and quality of life. Another common human experience is stress, whether that be short-term, acute stress, or long-term, chronic stress. Despite the significance and ubiquity of both PM and stress, the research base documenting the relations between them is sparse. This topic area necessitates additional research to delineate …

The Impact Of Stress On Steroid Hormones And Cue Reactivity In Smokers And Gamblers, Stephanie Elaine Wemm

Legacy Theses & Dissertations (2009 - 2024)

Addictions, both substance and behavioral, have been conceptualized as having similar biopsychosocial processes with different opportunistic expressions (Shaffer et al., 2004). Biological processes such as the hormonal response to stress as measured by cortisol, dehydroepiandrosterone (DHEA), and the ratio of the DHEA/cortisol may be among the variables underlying the disposition to develop an addictive disorder, regardless of whether it is a substance-based or a so-called behavioral addiction. The current study aimed to examine whether physiological and psychological reactions to stress are similar in high-frequency smokers and gamblers. The subjective (urges, cravings) and physiological responses (skin conductance and heart rate) of …

The Effect Of Two Modes Of Aerobic Assessment On Fifth Grade Students' Self Efficacy, Debra Roth

Walden Dissertations and Doctoral Studies

Declining youth physical activity levels and lack of aerobic fitness have been well documented with a corresponding rise in obesity levels and health issues. Based on Bandura's social cognitive theory, healthy physical activity levels and aerobic fitness are strongly connected to positive physical activity self-efficacy beliefs. This study examined whether student physical activity self-efficacy, motivation, and effort were different for the FitnessGram-® (FG) 1-Mile Run when compared to the 15-minute Aerobic Assessment Based on Improvement (AABI). A concurrent mixed method quasi-experimental approach measured 5th grade students' physical activity self-efficacy beliefs through a pretest and posttest survey while aerobic assessment scores …

Characterization Of Sex Differences In The Reinforcing Effects Of Nicotine, Rodolfo Jesus Flores Garcia

Open Access Theses & Dissertations

It is presently unclear whether ovarian hormones, such as estradiol (E2) promote the reinforcing effects of nicotine in females. Thus, we compared extended access to nicotine intravenous self-administration (IVSA) in intact male, intact female, and OVX female rats (Study 1) as well as OVX females that received vehicle or E2 supplementation (Study 2). The E2 supplementation procedure involved a 4-day procedure involving 2 days of vehicle administration and 2 days of E2 administration. Two doses of E2 (25 or 250 ug) were assessed in separate groups of OVX females in order to examine the dose-dependent effects of this hormone on …

Differentiating The Effects Of Animal-Assisted Versus Equine Facilitated Psychotherapy On Positive Psychological Outcomes Through A Stress Induction Context, Catherine J.V. Jones

College of Graduate Studies: Theses & Dissertations

The unique benefits of Equine Facilitated Psychotherapy (EFP) such as the human-horse bond, a non-traditional therapy setting, and performing altruistic acts are thought to facilitate positive change in humans. One mechanism by which positive changes occur is through improved coping and resilience in the face of stress. To date, only a handful of correlational studies speak to the potential effects of EFP on resilience-based outcomes. Thus, this study sought to address this gap in the literature by exploring the benefits of EFP compared to traditional Animal Assisted Therapy (AAT) in an experimental context. Specifically, we examined the effects of different …

Sensory-Specific Satiety Is Intact In Rats Made Obese On A High-Fat, High-Sugar Choice Diet., Kevin P. Myers

Faculty Journal Articles

Sensory-specific satiety (SSS) is the temporary decreased pleasantness of a recently eaten food, which inhibits further eating. Evidence is currently mixed whether SSS is weaker in obese people, and whether such difference precedes or follows from the obese state. Animal models allow testing whether diet-induced obesity causes SSS impairment. Female rats (n = 24) were randomly assigned to an obesogenic high-fat, high-sugar choice diet or chow-only control. Tests of SSS involved pre-feeding a single palatable, distinctively-flavored food (cheese- or cocoa-flavored) prior to free choice between both foods. Rats were tested for short-term SSS (2 h pre-feeding immediately followed by 2 …

The Mediating Effects Of Cortisol On The Relationship Between Conscientiousness And Judgments Of Learning, Katherine D. Miller

Graduate Theses/Dissertations

Cortisol assists in facilitating stress response. A peak in cortisol levels can be seen between 20 and 40 minutes after exposure to the stressful event. Judgments of learning (JOLs) are within the field of metacognition and are judgments individuals make about how well they feel they have acquired the target information. Many factors influence the accuracy of these judgments, including whether they are immediate or delayed. Conscientiousness is a characteristic of personality that is associated with responsibility and organization. Individuals high in conscientiousness are more likely to have positive health related outcomes. A relationship between conscientiousness and the appraisal of …

Psychopathy And The Effect Of Imitation On Empathetic Pain, Emily N. Lasko

College of Graduate Studies: Theses & Dissertations

Psychopathy is a disorder largely characterized by a marked deficit in empathy, however, the specificity and extent of the deficit is currently unclear. While it has been well-established in the literature that individuals higher in psychopathy tend to have intact Theory of Mind abilities and exhibit a deficient ability for affective empathy (Blair, 2005), the contribution of motor empathy to these abilities, particularly in regard to empathy for pain, has yet to be experimentally examined. Additionally, the possibility of imitation increasing motor empathic abilities has not been tested in this capacity. The goal of the current study was to further …

Behavioral Deficits Across Development In A Novel Mouse Model Of Fetal Ethanol Effects, Andrew B. Hawkey

Theses and Dissertations--Psychology

Fetal Alcohol Spectrum Disorders (FASD) are a spectrum of anatomical, developmental and neurobehavioral impairments resulting from ethanol (ETOH) exposure during fetal development. Efforts to develop and screen novel pharmacotherapies against fetal ETOH effects depend heavily upon rodent models to provide indicators of the safety and efficacy of such compounds, in addition to helping better understand the underlying mechanisms to develop and test these pharmacotherapies. The following experiments describe the development of a novel mouse model of FASD using behavioral batteries to assess behavioral or cognitive deficits in juvenile and adolescent offspring (Experiment 1, Experiment 2) and whether deficits with this …

Antidepressant-Like Effects Of Amisulpride, Ketamine, And Their Enantiomers On Differential-Reinforcement-Of-Low-Rate (Drl) Operant Responding In Male C57/Bl/6 Mice, Doug Smith

Theses and Dissertations

Major depressive disorder (MDD) is a widespread psychiatric disorder that affects millions of people worldwide and is hypothesized to occur due to impairments in several neurotransmitter systems, including the monoaminergic and glutamatergic neurotransmitter systems. Antidepressant medications targeting multiple monoamine neurotransmitters have been shown to be effective for the treatment of depression. Racemic amisulpride is an atypical antipsychotic that has been used at low doses to treat dysthymia, a mild form of depression, and functions as an antagonist at DA_2/3, 5-HT_2B, and 5-HT₇ receptors. Recent preclinical studies have suggested that the S(+) isomer may be more …

If It Feels Good, View It: Selective Exposure And Desensitization Moderate The Association Between Video Gameplay And Pleasure-Oriented Aggression, Mejdy M. Jabr

LSU New Orleans Theses and Dissertations

A number of studies have indicated that violent video gameplay is associated with higher levels of aggression, and desensitization to violent content contributes to this association. Utilizing a rapid serial visual presentation (RSVP) task, the current study used event-related potentials (ERPs) to investigate selective attention (N1 activation), cognitive control (N2 activation), and desensitization (P3 activation) as neurocognitive mechanisms potentially underlying the association between gameplay and subtypes of aggression. Results showed video game players and non-players differed significantly in brain activation when engaged with violent imagery. N1 and P3 amplitude moderated the association between gameplay and pleasure-oriented aggression. Follow-up analyses further …

Habitat Use By Bottlenose Dolphins, Tursiops Truncatus, In Roanoke Sound, North Carolina, Shauna Marisa Mcbride

Dissertations

Information on the habitat use of a species is important to develop conservation efforts and management strategies for that species. Roanoke Sound, North Carolina is primarily a seasonal habitat for bottlenose dolphins, Tursiops truncatus, from late spring to early fall, but little information is known about how dolphins use this area. Transect survey data and opportunistic survey data collected by the Outer Banks Center for Dolphin Research from 2009 to 2015 were used to analyze dolphin habitat use. The objectives of this project were to: 1) identify areas that were important to dolphins, 2) determine which behaviors were observed …

The Importance Of Serotonergic And Adrenergic Receptors For The Induction And Expression Of One-Trial Cocaine-Induced Behavioral Sensitization, Krista N. Rudberg

Electronic Theses, Projects, and Dissertations

Addiction is a complex process in which behavioral sensitization may be an important component. While the behavioral effects of sensitization are well established, the intricate neurobiology of the phenomenon is still largely unknown. Dopamine systems mediate the induction of behavioral sensitization in adult rats, but there is a large amount of evidence showing that other neurotransmitter systems also modulate the induction process. For example, the α1b-adrenergic and 5-HT_2A receptor systems are known to modulate the sensitized responding of adult rats, but the roles that these receptor systems play in the induction and expression of behavioral sensitization during the preweanling …

Using Auditory Feedback To Improve Striking For Mixed Martial Artists, Frank Krukauskas Krukauskas

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to evaluate, auditory feedback as a training procedure to increase the effectiveness of throwing a "right cross.” Auditory feedback was evaluated in multiple baselines across behaviors design with 4 mixed martial arts students, two males and two females, 25-54 years old. The percentage of correct steps of the right crosses.” was stable .during baseline for all participants improved substantially following the introduction of the auditory feedback, and maintained at 90 percent or more for all participants during follow-up.

The Effect Of Increased Sleep On The Circadian Rhythm Of Salivary Cortisol Concentrations, Mariah Jacqueline Scott

Seton Hall University Dissertations and Theses (ETDs)

Cortisol is a salivary marker for the hypothalamic-pituitary-adrenal axis (HPA) component of the stress response. The activity of the HPA demonstrates a circadian rhythm. It is well known that sleep deprivation increases cortisol concentrations. In this study, we looked at the effect of an increase of one-hour sleep for one month on the circadian rhythm of the HPA.

Eight college subjects (n=8) collected saliva during their normal sleep wake cycle every 4 hours for 24 hours. Saliva collections were repeated after a month of increase of sleep by 1-hour. The subjects also completed demographic forms that asked for age, sex, …

Effects Of Auditory Vection Speed And Directional Congruence On Perceptions Of Visual Vection, Isabella Alexis Gagliano

Psychology Theses & Dissertations

Spatial disorientation is a major contributor to aircraft mishaps. One potential contributing factor is vection, an illusion of self-motion. Although vection is commonly thought of as a visual illusion, it can also be produced through audition. The purpose of the current experiment was to explore interactions between conflicting visual and auditory vection cues, specifically with regard to the speed and direction of rotation. The ultimate goal was to explore the extent to which aural vection could diminish or enhance the perception of visual vection. The study used a 3 × 2 within-groups factorial design. Participants were exposed to three levels …

Alleged Insanity: Frank Johnson Sr., Racial Injustice, And The Failure Of The Mental Health Care System In South Carolina, Jonathon P. Johnson

Senior Theses

This thesis is about Frank Johnson Sr. and the circumstances that led to his downfall as a farmer and father of six, to his tragic death in the isolation of a racially segregated mental institution 18 miles away from his home. Using his life and incarceration at the South Carolina State Park mental health facility, I argue that racial injustice contributed to his tragic death and the woefully inadequate treatment thousands of African Americans in South Carolina received during Jim Crow. Additionally, I argue that the tragic circumstances around my great grandfather’s institutionalization and death were part of an enduring …

Observational Assessment Of Empathy In Parent-Child Verbal Exchanges And Their Influence On Child Behavior, Patty Carambot

Dissertations, Theses, and Capstone Projects

Empathy, the ability to both experientially share in and understand others’ thoughts, behaviors, and feelings, is vital for human adaptation. Deficits in empathy development have implications across the lifespan for the development of prosocial behavior, social functioning, mental health disorders, and risk for antisocial behavior (e.g., Guajardo, Snyder, & Petersen, 2009; Moreno, Klute & Robinson, 2008). In light of these societal and individual burdens, it is imperative to foster and strengthen the development of this ability early in life to prevent or ameliorate such negative outcomes. This type of prevention can take a variety of forms, but parent and child …

Ptsd From Childhood Trauma As A Precursor To Attachment Issues, Christy Owen

Fidei et Veritatis: The Liberty University Journal of Graduate Research

The past 20 years have been turbulent regarding Reactive Attachment Disorder (RAD), with conflicting research about its causes, effects, treatment, and prognosis. The current diagnostic criteria in the DSM-5 fails to adequately address this disorder. A number of deviant and maladaptive behaviors common amongst children with RAD are not even mentioned in the diagnostic criteria. As such, the diagnostic definition is almost unidentifiable or incompatible with real-life conduct manifestations of the disorder. Rather, this author contends that RAD is foundationally a unique and extreme form of Posttraumatic Stress Disorder (PTSD) from Early Childhood Trauma. The child endured unspeakable neglect and/or …

The Bilingual Brain, Victoria A. James

Journal of Counseling and Psychology

This literature review explores the neurocognitive effects of the bilingual brain. Many areas of bilingualism are examined such as age of acquisition, which is when the second language is attained, and memory. The three types of bilingual memory are implicit memory, which is procedural memory, explicit memory, which is declarative memory, and episodic memory, which is autobiographical memory. In relation to the bilingual brain, cognition, control, and /lateralization are also reviewed. Finally, second language (L2) learning strategies are considered. The objective of this study is to obtain an understanding on how two or more languages are acquired and processed in …

Emotion Moderates The Association Between Htr2a (Rs6313) Genotype And Antisaccade Latency, Mark S. Mills, Olivia Wieda, Scott F. Stoltenberg, Michael Dodd

Department of Psychology: Faculty Publications

The serotonin system is heavily involved in cognitive and emotional control processes. Previous work has typically investigated this system’s role in control processes separately for cognitive and emotional domains, yet it has become clear the two are linked. The present study, therefore, examined whether variation in a serotonin receptor gene (HTR2A, rs6313) moderated effects of emotion on inhibitory control. An emotional antisaccade task was used in which participants looked toward (prosaccade) or away (antisaccade) from a target presented to the left or right of a happy, angry, or neutral face. Overall, antisaccade latencies were slower for rs6313 C allele homozygotes …

Reactivity And Recovery Among Oif/Oef/Ond Combat Veterans: Do Those With Subthreshold Ptsd Differ From Veterans With And Without Ptsd?, Paula Castro-Chapman

USF Tampa Graduate Theses and Dissertations

This study expanded the current literature by assessing PTSD in relation to reactivity and recovery from negative emotional arousal among OEF/OIF/OND Veterans. Cardiac impedance was employed during a speech task and a trauma imagery procedure. Those in the PTSD-S group displayed lower SBP and higher TPR reactivity relative to the PTSD- and PTSD+ groups; lower CO reactivity relative to the PTSD+ group; and more CO recovery than those in the PTSD+ group to the trauma task. For speech task, Veterans in the PTSD-S group exhibited lower HR reactivity for both speech preparation and delivery than those in the PTSD- group. …

Neural Mechanisms Of Action Switching Moderate The Relationship Between Effortful Control And Aggression, Eric L. Rawls

LSU New Orleans Theses and Dissertations

Aggression and violence are social behaviors that exact a significant toll on human societies. Individuals with aggressive tendencies display deficits in effortful control, particularly in affectively charged situations. However, not all individuals with poor effortful control are aggressive. This study uses event-related potentials (ERPs) to decompose the chronology of cognitive functions underlying the link between effortful control and aggression. Specifically, this study investigates which ERPs moderate the effortful control - aggression association. We examined three successive ERP components (P2, N2 and P3) for stimuli that required effortful control. Results indicated that N2 activation, but not P2 or P3 activation, moderated …

An Investigation Of Short-Term Plasticity In Human Motor Cortex, Matthew Alan Gannon

Graduate Theses and Dissertations

Transcranial magnetic stimulation (TMS) produces a transient magnetic field that activates underlying cortical tissue by eliciting an electrical discharge of the neurons in the targeted area. Repetitive TMS (rTMS) uses patterns of repetitive TMS pulses and has been reliably shown to produce changes in the state of cortical excitability outlasting the time of stimulation. One such protocol that has demonstrated states of increased excitability is intermittent theta burst stimulation (iTBS). This method applies high-frequency bursts (50Hz) of pulses every 200 ms in trains of ten bursts. The effects of and differences between rTMS protocols have been investigated since gaining popularity …

Perseverance: Psychospiritual And Genetic Perspectives, Tony N. Jelsma, Arielle Johnston, Bruce Vermeer

Faculty Work Comprehensive List

Perseverance constitutes a quality that motivates humankind to press onward usually in the face of significant adversity and resistance. Perseverance is also important in the Christian life. The apostle Paul, using athletic training metaphors, frequently urges his readers to persevere in the faith, even describing his own life as a fight and a race (2 Tim.4:7). Yet, certain groups of people seem to possess a greater measure of perseverance than others have. We are therefore led to ask, “Can our ability to persevere be, in God’s providence, at least partly genetically influenced?”

The Contribution Of The Pineal Gland On Daily Rhythms And Masking In Diurnal Grass Rats, Arvicanthis Niloticus, Dorela D. Shuboni, Amna A. Agha, Thomas K. H. Groves, Andrew J. Gall

Faculty Publications

Melatonin is a hormone rhythmically secreted at night by the pineal gland in vertebrates. In diurnal mammals, melatonin is present during the inactive phase of the rest/activity cycle, and in primates it directly facilitates sleep and decreases body temperature. However, the role of the pineal gland for the promotion of sleep at night has not yet been studied in non-primate diurnal mammalian species. Here, the authors directly examined the hypothesis that the pineal gland contributes to diurnality in Nile grass rats by decreasing activity and increasing sleep at night, and that this could occur via effects on circadian mechanisms or …

Examination Of Methamphetamine Reinstatement In Female And Male Rats: A Pre-Clinical Model Of Relapse, Steven T. Pittenger

Department of Psychology: Dissertations, Theses, and Student Research

Methamphetamine (meth) dependence is often characterized by persistent and chronic relapse (i.e., return to drug use). There is growing pre-clinical and human evidence suggesting females are at greater risk to relapse. The set of studies presented in this dissertation extended this limited evidence by identifying sex-dependent neural substrates correlated with meth-triggered reinstatement (Experiment 1) and by examining sex-differences in reinstatement triggered by drugs of abuse that are commonly co-abused with meth (Experiment 2). Female and male rats were trained to self-administer meth, received subsequent extinction sessions, and then tested for reinstatement. In Experiment 1, rats were perfused following reinstatement testing …

Nicotine And Methylphenidate Chornic Exposure On Adult Cannabinoid Receptor Agonist (Cp 55,940) Place Conditioning In Male Rats, Christopher P. Plant

Electronic Theses, Projects, and Dissertations

A problematic connection has been reported between those who use nicotine related products alone or in combination with ADHD medications, like methylphenidate (MPH), in late childhood or early adolescence and the increased likelihood of later marijuana abuse in adulthood. Pre-clinical studies have found that the use of nicotine during the early adolescence period produces enduring changes to the endocannabinoid system in the brain. Since CB agonists, like marijuana, exert their effect through the eCB system, it is possible that early nicotine use may alter the rewarding nature of CB agonists in adulthood. In addition, MPH has also been shown to …