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Articles 1 - 30 of 167
Full-Text Articles in Biological Psychology
The Hypnagogic State And Hypnagogic Constraint Modulation In Ocd, Ari Rad
The Hypnagogic State And Hypnagogic Constraint Modulation In Ocd, Ari Rad
Academic Leadership Journal in Student Research
The past few decades of scholarly inquiries on the topic of the hypnagogic state and N1 sleep onset have introduced a new understanding of human general mentation. The underlying phenomenological, psychological, and neurological aspects of the hypnagogic state have been explored in depth by researchers. Hypnagogia and N1 sleep onset have been associated with creativity, spontaneous access to insights, symbolic representation of cognitive processes, and visual and auditory perceptions. The default mode network (DMN) has been largely associated with creativity and spontaneous thinking during N1 sleep onset. This paper reviews the basics of the neurology and phenomenology of N1 and …
From Stranger To Self: The Role Of Familiarity In Modulating The N170 And N250 Erp Components, Tabish Gul
From Stranger To Self: The Role Of Familiarity In Modulating The N170 And N250 Erp Components, Tabish Gul
Dissertations
This study investigated how varying levels of face familiarity modulate the N170 and N250 event-related potential (ERP) components, two neural markers of face perception and recognition. While the N250 is widely considered familiarity-sensitive, the N170 has traditionally been linked to the structural encoding stage of face perception. However, recent research suggests that face familiarity may also influence N170 amplitude and latency. While most previous studies have compared up to three familiarity levels, the present study examined five levels of familiarity: own face, friend’s face, famous face, experimentally familiar face, and unfamiliar face. Twenty-six participants viewed face images while completing a …
Impact Of Caffeine On Participant Memory For A Stressful Experience And The Development Of Intrusive Memories, Jaycee L. Kirkland, Kaylina R. Mcclenen, Natalina E. Porter, Sarah M. Wood, Julia Gross, Madilyn E. Paphanchith, Kelsey M. Siereveld, Jasmine Ic Ifeakanwa, Caeden M. Gurganus, Koen N. Suzelis, Aiden J. Farrell, Boyd R. Rorabaugh, Phillip R. Zoladz
Impact Of Caffeine On Participant Memory For A Stressful Experience And The Development Of Intrusive Memories, Jaycee L. Kirkland, Kaylina R. Mcclenen, Natalina E. Porter, Sarah M. Wood, Julia Gross, Madilyn E. Paphanchith, Kelsey M. Siereveld, Jasmine Ic Ifeakanwa, Caeden M. Gurganus, Koen N. Suzelis, Aiden J. Farrell, Boyd R. Rorabaugh, Phillip R. Zoladz
ONU Student Research Colloquium
Most individuals consume caffeine on a daily basis. Research has shown that caffeine stimulates the release of glucocorticoids and catecholamines and can enhance cognition. Caffeine also amplifies stress-induced increases in arousal and aggravates PTSD-like symptoms. Thus, we examined the impact of caffeine on memory for a stressful experience and intrusive memories related to that experience. Undergraduate students ingested caffeine or a placebo. Thirty minutes later, they were exposed to the Trier Social Stress Test (TSST; stress condition) or friendly-TSST (f-TSST; control condition), both of which were designed to enable participant memory for the experiences to be quantified. In each condition, …
Practical Considerations For Conducting Canine Behavioral Science, Lucrezia Lonardo, Madeline H. Pelgrim, Jeffrey R. Stevens
Practical Considerations For Conducting Canine Behavioral Science, Lucrezia Lonardo, Madeline H. Pelgrim, Jeffrey R. Stevens
Jeffrey Stevens Publications
Research on behavior in domestic dogs (Canis familiaris) has increased rapidly recently due to the interest in them as pets, working dogs, and model species for understanding evolution, domestication, and even human health. This interest in canine behavioral science has resulted in the creation of dozens of dog lab worldwide, with more starting every year. Our aim here is to review practical issues that potential dog researchers might consider when deciding how to set up a dog lab and conduct research in canine behavioral science. We hope that this can offer a path forward in promoting high-quality, cutting-edge …
A Child On Stand: The Impact Of Experiencing Trauma On Children’S Testimonial Efficacy In Legal Proceedings, Morgan Sweger
A Child On Stand: The Impact Of Experiencing Trauma On Children’S Testimonial Efficacy In Legal Proceedings, Morgan Sweger
Williams Honors College, Honors Research Projects
Children who are victims of physical, sexual, emotional, or verbal abuse are nearly always left deeply traumatized by such events. In extreme cases, abused children may be asked to testify against their abuser(s) in legal proceedings, recounting their trauma in front of a room full of strangers. For some, the trauma of abuse may influence a child’s ability to effectively recall and describe their experiences and for others, the process of participating in legal proceedings creates deeper wounds. Research has aimed to understand whether children lack the ability to contribute sufficient testimonies during investigations of abuse and how these investigations …
Effects Of Pressure-Based Virtual Reality Training On Mental Toughness In Athletes, Rylee J. Aspinwall
Effects Of Pressure-Based Virtual Reality Training On Mental Toughness In Athletes, Rylee J. Aspinwall
UNF Graduate Theses and Dissertations
Athletes often underperform in high-pressure situations due to challenges in emotional regulation rather than deficits in physical skill. Mental toughness, broadly defined as the ability to maintain performance under stress, is a key determinant of athletic success but remains difficult to train using traditional methods. Virtual reality (VR) offers a controlled and immersive environment for simulating competitive pressure; however, its application for training mental toughness remains limited. The present study examined the effects of pressure-based VR training on psychological and physiological responses in collegiate baseball and softball athletes. Participants completed up to eight VR training sessions under either high-pressure or …
Physiological Response To Concealed Information In A Mock-Crime Paradigm, Ezra Koenigsberg, Tamya Mchenry, Jasmine Manzana, Taylor Powell, Samantha Jackson
Physiological Response To Concealed Information In A Mock-Crime Paradigm, Ezra Koenigsberg, Tamya Mchenry, Jasmine Manzana, Taylor Powell, Samantha Jackson
Science University Research Symposium (SURS)
The Concealed Information Test (CIT), based on Lykken’s guilty knowledge framework, measures physiological responses when individuals recognize crime-related details compared to neutral alternatives. Previous studies show that variations in stimulus presentation enhance the CIT’s accuracy, especially through changes in electrodermal activity and heart rate. However, few studies have tested whether a Qualtrics-based mock-crime version of the CIT can replicate these physiological patterns. This study addresses that gap by adapting the CIT for a digital research environment. The goal is to determine whether participants show greater physiological arousal—measured through skin conductance, heart rate, and respiration—when exposed to crime-related “critical” stimuli compared …
Neuroanatomical And Morphometric Differences In Children Who Stutter, Mohammad A. Khan
Neuroanatomical And Morphometric Differences In Children Who Stutter, Mohammad A. Khan
Honors Scholar Theses
Childhood-Onset Fluency Disorder commonly known as stuttering is a neurodevelopmental speech disorder characterized by disruptions in speech fluency. While genetic and neurobiological factors are implicated, the structural brain differences underlying stuttering remain unclear. This study investigated neuroanatomical alterations in children who stutter (CWS) compared to typically fluent children (TFC), focusing on gray matter volume, cortical thickness, and surface area in speech-related regions; the Inferior Frontal Gyrus, Middle Temporal Gyrus, and Pre-motor Operculum. High-resolution MRI data from 100 children (48 CWS, 52 TFC) aged 3–12 years were analyzed using FreeSurfer. Group comparisons revealed no statistically significant differences in cortical thickness, surface …
Stress As A Means Of Success: Investigating The Effect Of Stress Appraisals On Willpower, Ego Depletion, And Physiological Responses In College Students, Anna Minor
Honors College Theses
Stress impacts our emotions, cognition, behavior, and health. Although stress is abundant and unavoidable, recent research suggests our perception of stress can strongly influence its outcomes. The Biopsychosocial Model of Challenge and Threat (BPS) states that we appraise a stressful scenario in one of two ways: challenge or threat. A challenge appraisal involves a positive perception of stress and is associated with lower physiological output while a threat appraisal involves a negative perception of stress and increased physiological arousal. The current research seeks to apply the BPS to a cognitive task and consider its relation to willpower, ego depletion, and …
Can Dyslexia Diagnosis Induce A Stereotype Threat Effect? A Literature Review And Research Proposal, David H. Harris
Can Dyslexia Diagnosis Induce A Stereotype Threat Effect? A Literature Review And Research Proposal, David H. Harris
Cal Poly Humboldt theses and projects
Dyslexia is a recognized psychiatric diagnosis in the DSM-5, categorized as a specific language disorder. Dyslexia is a hidden disability that affects how individuals process auditory and visual information. Many people have heard of dyslexia but it is largely misunderstood, even by educational professionals, and its general association with learning disability can be the basis for negative stereotyping and discrimination of people with dyslexia. The ‘Stereotype threat effect’ is a term from social psychology research referring to situations where one’s performance on a task is influenced by their identification with a social group that has a well-known stereotype about their …
Money Matters: Investigating The Emotional, Cognitive, And Biological Pathways Connecting Maternal Early Life Financial Insecurity And Parenting Quality, Elise Power, Stacey N. Doan
Money Matters: Investigating The Emotional, Cognitive, And Biological Pathways Connecting Maternal Early Life Financial Insecurity And Parenting Quality, Elise Power, Stacey N. Doan
CMC Senior Theses
Early life adversity has been shown to have a variety of negative effects on adult functioning, including parenting quality, with implications for child wellbeing. Adverse early life experiences including poverty have been linked to long-term disruptions in emotional, cognitive, and physiological functioning that compromise the ability to provide sensitive, nurturing care. The present study investigated whether emotional regulation difficulties, physiological regulation, and cognitive function mediate the relationship between early life financial insecurity and parenting quality. A sample of 132 mother-child dyads completed self-report measures, biological samples, and cognitive assessments. A multiple mediation model ran in SPSS, revealed a significant indirect …
Weighted Family History Density Of Substance Use: Influence On Participant Substance Use Onset, Escalation, And Duration, Carleigh A. Litteral
Weighted Family History Density Of Substance Use: Influence On Participant Substance Use Onset, Escalation, And Duration, Carleigh A. Litteral
Theses and Dissertations--Psychology
Substance use disorders impose a staggering toll on the United States (U.S.), straining healthcare systems, destabilizing communities, and profoundly impacting both individuals and families. Approximately one in six Americans aged 12 and older had a past-year substance use disorder in 2022 (Key Substance Use, 2022), and nearly one-third of adults experience a substance use disorder in their lifetime (Wu, 2010), contributing to an economic burden exceeding $400 billion annually (National Drug Threat Assessment, 2011). Family history of substance use disorders is a key predictor of vulnerability, with individuals who have affected relatives being 2–8 times more …
Exploring The Effects Of Transcranial Direct Current Stimulation Of The Right Inferior Frontal Gyrus On Inhibitory Control In Posttraumatic Stress Disorder, Colton Rippey
Theses and Dissertations--Psychology
Background: The right inferior frontal gyrus (rIFG) is implicated in stop signal reaction time (SSRT) performance – a common measure of inhibitory control – and emotional expression and control. Individuals with posttraumatic stress disorder (PTSD) exhibit poorer stop SSRT performance, which is associated with rIFG hypoactivity. Neuromodulation of the rIFG with transcranial direct current stimulation (tDCS) can significantly improve inhibitory control and reduce fearful responding to threatening stimuli. Research has yet to test the effects of multifocal tDCS targeting the rIFG on inhibitory control or emotional reactivity in individuals with PTSD.
Methods: The current study aims to examine the impact …
Terpenes Mitigate Thc-Induced Working Memory Deficits: Behavioural Evidence Of The Entourage Effect Using A 2-Component Operant Memory Task, Lara Mitchell
Theses and Dissertations (Comprehensive)
Most research on cannabis and cognitive function has focused on delta-9-tetrahydrocannabinol (THC). However, this approach overlooks the complex chemical composition of cannabis products consumed by the public, which often includes cannabidiol (CBD) and various terpenes. These additional constituents may interact with THC to modulate its effects, a phenomenon known as the entourage effect. While this theory has gained traction, experimental evidence for the cognitive impact of terpenes in combination with THC remains limited. This study aimed to assess whether terpenes can mitigate THC-induced cognitive deficits using a 2-Component Operant Memory task. Male Sprague-Dawley rats received intraperitoneal injections of either …
Observing Dynamic Emotional Faces From Many Generations, Tashaunda Grimmett
Observing Dynamic Emotional Faces From Many Generations, Tashaunda Grimmett
Masters Theses & Specialist Projects
This study sought to further understand emotion perception capabilities in younger and older adults. Previous studies examining emotion perception have consistently found emotion recognition deficits with age. The most common technique used to investigate age differences in emotion perception is a label selection task that presents static images of actors expressing emotion. More recently, dynamic stimuli have been developed; they portray realistic facial expressions that are more comparable to what one sees in real life. The use of dynamic stimuli has been found to ameliorate most age differences in the recognition of basic emotion categories. The current study presented dynamic …
Cognitive Differences In Parkinson’S Disease With Amyloid Positivity And Negativity, Kenya Luna
Cognitive Differences In Parkinson’S Disease With Amyloid Positivity And Negativity, Kenya Luna
Electronic Theses, Projects, and Dissertations
In Parkinson’s Disease (PD), research has shifted to investigate how biomarkers commonly seen in Alzheimer’s Disease (AD), such as amyloid beta (AB), may be associated with cognitive functioning in PD. AB is considered a reliable biomarker for AD pathology, however in PD there is a lacking biomarker that can accurately reflect severity of cognitive impairment. AD research has shown an association between low AB and cognitive decline, but the data in PD has mixed results. Most studies that analyze cognitive decline and biomarkers do not use a cutoff level and the few that do have a threshold vary greatly in …
Psychophysical And Pharmacological Models Of Visual Hallucination, Nathan H. Heller
Psychophysical And Pharmacological Models Of Visual Hallucination, Nathan H. Heller
Dartmouth College Ph.D Dissertations
Visual hallucinations are visual experiences that are spontaneously generated by the brain, in the absence of appropriate external stimuli. Understanding the neural processes that give rise to these experiences is a complex challenge that spans the domains of psychology, neuroscience, and clinical practice. Model hallucinations can serve as a valuable tool in this context. They allow researchers to study hallucinatory experiences under controlled conditions, thus providing insights into their behavioral and neural underpinnings, which can facilitate the development of effective treatments. By creating models that emulate different aspects of hallucinatory experience, whether through pharmacological means, sensory manipulation, or cognitive tasks, …
Pre-Stimulus Anticipation And Unconscious Fear Learning Disparities In Individuals With Varying Levels Of Anxiety, Anastasiya Rumyantseva Kharlamova
Pre-Stimulus Anticipation And Unconscious Fear Learning Disparities In Individuals With Varying Levels Of Anxiety, Anastasiya Rumyantseva Kharlamova
Dissertations, Theses, and Capstone Projects
The current study employed a Pavlovian conditioning paradigm to investigate the influence of pre-stimulus unconscious threat anticipation on subsequent fear responses in associative learning. Additionally, we explored the differences in pre-stimulus anticipation among individuals with varying levels of anxiety. Electrodermal response (EDA) was chosen as a primary measure due to its robustness in fear conditioning paradigms. Moreover, the State-Trait Anxiety Inventory (STAI) was utilized to assess anxiety levels in participants. Twenty-seven subjects were recruited to determine if pre-stimulus skin conductance responses (SCR) would exhibit stimulus-specific patterns influenced by implicit cues (L-shaped configurations) that indicated an upcoming face or a house …
Anisotropy In Non-Rigidity Perception: The Role Of Anisotropies In Neural Populations, Akihito Maruya, Qasim Zaidi
Anisotropy In Non-Rigidity Perception: The Role Of Anisotropies In Neural Populations, Akihito Maruya, Qasim Zaidi
MODVIS Workshop
No abstract provided.
The Relationship Between Amygdala And Orbitofrontal Cortex Volume In The Context Of Oppositional Defiant Disorder, Rahul Alla
Honors Scholar Theses
Disobedient and rebellious attitude in children is on the rise and this type of behavior is categorized as Oppositional Defiant Disorder (ODD). ODD in children can be identified as a persistent pattern of angry or irritable mood, argumentative or defiant behavior or vindictiveness toward others according to the Diagnostic and Statistical Manual (DSM-5, Fifth Edition) of Mental Disorders.1 Children with ODD typically have difficulty regulating and processing their emotions. Issues with regulating emotions is defined as the process by which individuals “influence which emotions they have, when they have them, and how they experience and express them”.2 Dysregulation of emotions …
Exposure To The Trier Social Stress Test Enhances Central Detail Memory, Reduces False Memory, And Results In Intrusive Memories That Last For Days, Mercedes L. Stanek, Kayla Boaz, Taylor D. Niese, Kristen E. Long, Matthew S. Risner, John G. Blasco, Koen N. Suzelis, Kelsey M. Siereveld, Boyd R. Rorabaugh, Phillip R. Zoladz
Exposure To The Trier Social Stress Test Enhances Central Detail Memory, Reduces False Memory, And Results In Intrusive Memories That Last For Days, Mercedes L. Stanek, Kayla Boaz, Taylor D. Niese, Kristen E. Long, Matthew S. Risner, John G. Blasco, Koen N. Suzelis, Kelsey M. Siereveld, Boyd R. Rorabaugh, Phillip R. Zoladz
ONU Student Research Colloquium
Recent work has used a modified version of the well-known laboratory stressor, the Trier Social Stress Test (TSST), to study participant memory for a stressful experience. The paradigm is useful because, unlike most studies examining stress effects on memory, it allows investigators to measure what participants remember about the stressor, not unrelated information. It also presents an opportunity to model other stress-related symptoms, such as intrusive memories, but these have yet to be assessed with this paradigm. Intrusive memories have been notoriously difficult to measure in laboratory settings; most of this research involves participants watching arousing videos and subsequently reporting …
Addicted To The Beloved? A Comparison Of Craving For And Attention To Beloved And Vape Stimuli, Caitlyn Harriman
Addicted To The Beloved? A Comparison Of Craving For And Attention To Beloved And Vape Stimuli, Caitlyn Harriman
Theses
People who are in love seem to be addicted to their beloved. People who are in love have attentional biases for the beloved and people who are addicted have attentional biases for the substance they are using. This raises the question of how similar craving and attention are for the beloved and an addictive substance. However, there are no studies that directly compared craving and attention to the beloved and addictive stimuli. The aims of the current research were to directly compare subjective emotional experiences, sustained motivated attention, and early automatic attention for the beloved and vape stimuli, in people …
The Relationship Between Cognitive Impairment In Psychiatric Patients And Readmission Rate To An Inpatient Facility, Cherilyn Isis Schuff
The Relationship Between Cognitive Impairment In Psychiatric Patients And Readmission Rate To An Inpatient Facility, Cherilyn Isis Schuff
Theses and Dissertations
The primary intention of this study was to further understand the impact of assessing cognitive impairment in psychiatric patients, as a mediating factor on readmission rates. Mild cognitive dysfunction impacts a patient’s functional outcomes (Bowie & Harvey, 2006; Davis et al., 2012; Marcantonio, et al., 2001). Little information exists to guide best practices in the treatment of adults with cognitive impairment who are hospitalized for acute conditions (Davis et al., 2012). A cognitive impairment may impact patient prognosis and ability to function outside of a setting focused on stabilization. Neuropsychological testing is a valuable tool in predicting a patient’s cognitive …
Proteomic Profiles Of Cytokines And Chemokines In Moderate To Severe Depression: Implications For Comorbidities And Biomarker Discovery, Kathleen T. Watson, Jennifer Keller, Caleb M. Spiro, Isaac B. Satz, Samantha V. Goncalves, Heather Pankow, Idit Kosti, Benoit Lehallier, Adolfo Sequeira, William E. Bunney, Natalie L. Rasgon, Alan F. Schatzberg
Proteomic Profiles Of Cytokines And Chemokines In Moderate To Severe Depression: Implications For Comorbidities And Biomarker Discovery, Kathleen T. Watson, Jennifer Keller, Caleb M. Spiro, Isaac B. Satz, Samantha V. Goncalves, Heather Pankow, Idit Kosti, Benoit Lehallier, Adolfo Sequeira, William E. Bunney, Natalie L. Rasgon, Alan F. Schatzberg
Psychology Division Scholarship
Objective: This study assessed the proteomic profiles of cytokines and chemokines in individuals with moderate to severe depression, with or without comorbid medical disorders, compared to healthy controls. Two proteomic multiplex platforms were employed for this purpose. Metods: An immunofluorescent multiplex platform and an aptamer-based method were used to evaluate 32 protein analytes from 153 individuals with moderate to severe major depressive disorder (MDD) and healthy controls (HCs). The study focused on determining the level of agreement between the two platforms and evaluating the ability of individual analytes and principal components (PCs) to differentiate between the MDD and HC groups. …
The Power Of Polish: Exploring The Impact Of Nail Adornments On Perceptions Of Attraction, Sara Demichele
The Power Of Polish: Exploring The Impact Of Nail Adornments On Perceptions Of Attraction, Sara Demichele
Honors Theses
Understanding the significance of nail adornments in shaping perceptions of attractiveness and mate value provides insights into human behavior and preferences. In the current investigation, participants rated human nail length and color on physical attractiveness and partner desirability measures. Results revealed significant effects of nail length and color across different demographic groups. Medium-length nails consistently received higher ratings for physical attractiveness, cuteness, and partner desirability compared to short and long nails. White-colored nails were generally rated most attractive, while blue and black nails received the lowest ratings. Additionally, participants reported a moderate association between having manicured nails and feelings of …
Cognitive Functioning In Well-Controlled Asthma, Erin Walsh
Cognitive Functioning In Well-Controlled Asthma, Erin Walsh
West Chester University Doctoral Projects
Asthma is a common lung disease that impacts lung functioning through inflammatory based mechanisms. Past research suggests that decreased blood oxygenation due to asthma attacks may impair cognitive capabilities (Irani et al., 2017). Moreover, the observed differences in cognition between those with and without asthma may be associated with disease severity or asthma control respectively in asthma populations. The current study explored differences in cognitive functioning between college students with and without self-reported asthma. Sociodemographic data, self-reported asthma severity, and measures of asthma control were collected. The current study did not find significant differences in measures of cognitive efficiency between …
Direct Relationships Between The Five Internal Senses: The Extremes And In-Between Of The Inner Experience, Sydnie Hoyt, Camryn O'Neal, Miranda Brannum, Sara Bagley
Direct Relationships Between The Five Internal Senses: The Extremes And In-Between Of The Inner Experience, Sydnie Hoyt, Camryn O'Neal, Miranda Brannum, Sara Bagley
The Confluence
Inner experience of all 5 modalities were investigated to determine if there were correlations amongst them and how visual mental imagery and internal hearing were used in an applied story. Our sample (N = 137) completed the Vividness of Visual Imagery Questionnaire (VVIQ; Marks, 1973) and the Plymouth Sensory Imagery Questionnaire (Psi-Q; Andrade et al., 2013) to obtain trait measures of the different modalities within the inner experience. Results showed statistically significant positive correlations between each of the trait measures of the 5 sensory modalities (visual mental imagery, inner hearing, taste, smell, and touch). Based on their VVIQ total scores, …
Comparison Between The Effects Of Acute Physical And Psychosocial Stress On Feedback-Based Learning, Xiao Yang, Brittany Nackley, Bruce H. Friedman
Comparison Between The Effects Of Acute Physical And Psychosocial Stress On Feedback-Based Learning, Xiao Yang, Brittany Nackley, Bruce H. Friedman
Psychology Faculty Publications
Stress modulates feedback-based learning, a process that has been implicated in declining mental function in aging and mental disorders. While acute physical and psychosocial stressors have been used interchangeably in studies on feedback-based learning, the two types of stressors involve distinct physiological and psychological processes. Whether the two types of stressors differentially influence feedback processing remains unclear. The present study compared the effects of physical and psychosocial stressors on feedback-based learning. Ninety-six subjects (Mage = 19.11 years; 50 female) completed either a cold pressor task (CPT) or mental arithmetic task (MAT), as the physical or psychosocial stressor, while electrocardiography and …
An Erp Measure Of Non-Conscious Memory Reveals Dissociable Implicit Processes In Human Recognition Using An Open-Source Automated Analytic Pipeline, Richard J. Addante, Javier Lopez-Calderon, Nathan Allen, Carter Luck, Alana Muller, Lindsey Sirianni, Cory S. Inman, Daniel L. Drake
An Erp Measure Of Non-Conscious Memory Reveals Dissociable Implicit Processes In Human Recognition Using An Open-Source Automated Analytic Pipeline, Richard J. Addante, Javier Lopez-Calderon, Nathan Allen, Carter Luck, Alana Muller, Lindsey Sirianni, Cory S. Inman, Daniel L. Drake
Psychology Student Publications
Non-conscious processing of human memory has traditionally been difficult to objectively measure and thus understand. A prior study on a group of hippocampal amnesia (N = 3) patients and healthy controls (N = 6) used a novel procedure for capturing neural correlates of implicit memory using event-related potentials (ERPs): old and new items were equated for varying levels of memory awareness, with ERP differences observed from 400 to 800 ms in bilateral parietal regions that were hippocampal-dependent. The current investigation sought to address the limitations of that study by increasing the sample of healthy subjects (N = …
Sucrose Demand And Essential Value In Mice With Early-Life Exposure To Risperidone, Megan Federoff
Sucrose Demand And Essential Value In Mice With Early-Life Exposure To Risperidone, Megan Federoff
LSU Master's Theses
Second-generation antipsychotics (SGAs), such as risperidone, are widely prescribed to children, but the long-term effects of SGA treatment are not well understood. This study investigated the impact of early-life risperidone treatment on sucrose demand in mice in adulthood. Mice were administered risperidone or vehicle from postnatal day (PND) 33 to 60 and trained in adulthood (>PND 120) to nose poke for a sucrose solution reinforcer. The fixed ratio (FR) value (the number of responses required to produce sucrose delivery; the “price” of sucrose) was varied from 1 to 45, and the resulting consumption versus FR value data were analyzed …