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Articles 31 - 60 of 175
Full-Text Articles in Medicine and Health Sciences
Does Apnea-Hypopnea Index Alone Reflect Obstructive Sleep Apnea Severity?, Ömer Araz, Di̇dem Pulur, Eli̇f Yilmazel Uçar, Mehmet Meral, Ali̇ Meti̇n Görgüner, Meti̇n Akgün
Does Apnea-Hypopnea Index Alone Reflect Obstructive Sleep Apnea Severity?, Ömer Araz, Di̇dem Pulur, Eli̇f Yilmazel Uçar, Mehmet Meral, Ali̇ Meti̇n Görgüner, Meti̇n Akgün
Turkish Journal of Medical Sciences
We aimed to assess whether there was a correlation between the apnea-hypopnea index (AHI), desaturation time under 90% (DTU-90), and mean saturation (MS) levels and the parameters associated with tissue hypoxia. Materials and methods: A total of 144 subjects were included in the study. Blood C-reactive protein levels, blood uric acid levels, and urine microalbumin levels were measured and the urine uric acid/creatinine ratio and urine microalbumin/creatinine ratio were calculated. Results: Our study results suggest that MS and DTU-90, as well as the AHI, are correlated with the parameters reflecting hypoxemia and the other events secondary to hypoxia. Conclusion: MS …
Effect Of Hepatic Steatosis On Virological Response To Nucleos(T)Ide Analogs Therapy In Patients With Chronic Hepatitis B, Ahmet Karaman, Şebnem Gürsoy, Işin Soyuer, Hati̇ce Karaman, Muhammet Edi̇p Torun, Mustafa Alper Yurci̇, Mevlüt Başkol, Kadri̇ Güven, Ömer Özbakir, Mehmet Yücesoy
Effect Of Hepatic Steatosis On Virological Response To Nucleos(T)Ide Analogs Therapy In Patients With Chronic Hepatitis B, Ahmet Karaman, Şebnem Gürsoy, Işin Soyuer, Hati̇ce Karaman, Muhammet Edi̇p Torun, Mustafa Alper Yurci̇, Mevlüt Başkol, Kadri̇ Güven, Ömer Özbakir, Mehmet Yücesoy
Turkish Journal of Medical Sciences
To evaluate the impact of hepatic steatosis on the outcome of treatment in patients with chronic hepatitis B infection treated with oral antiviral therapy. Materials and methods: The study was designed in Erciyes University Medical Faculty Department of Gastroenterology. Patients who received oral antiviral therapy because of chronic hepatitis B were included in the study. Liver biopsy specimens were re-evaluated and classified according to Brunt’s steatosis classification. Virological response to oral antiviral therapy was compared between patients with and without steatosis. Results: One hundred and nineteen patients were included in the study, of which 36.1% had hepatic steatosis. Virological response …
Aeg-1 Expression In Invasive Ductal And Lobular Breast Cancers And Its Relationship With Prognostic Parameters, Havva Erdem, Murat Oktay, Ali̇ Kemal Uzunlar, Ümran Yildirim, Handan Ankarali, Mehmet Yaşar
Aeg-1 Expression In Invasive Ductal And Lobular Breast Cancers And Its Relationship With Prognostic Parameters, Havva Erdem, Murat Oktay, Ali̇ Kemal Uzunlar, Ümran Yildirim, Handan Ankarali, Mehmet Yaşar
Turkish Journal of Medical Sciences
The astrocyte-elevated gene-1 (AEG-1, also known as metadherin) is associated with various aspects of tumour malignancy; however, little knowledge is available related to the role of AEG-1 in ductal and lobular carcinomas. The aim of this study was to investigate the relationship of AEG-1 with the prognostic parameters in invasive ductal and lobular carcinomas. Materials and methods: This study was conducted on a total of 72 paraffin-embedded breast tumour samples. They consisted of 61 ductal and 11 lobular carcinomas. Breast tumour samples were stained for AEG-1. The prognostic parameters were compared with the results of AEG-1 stains. Results: We observed …
Investigations Of Als1 And Hwp1 Genes In Clinical Isolates Of Candida Albicans, Melek İnci̇, Mustafa Altay Atalay, Burçi̇n Özer, Ömer Evi̇rgen, Ni̇zami̇ Duran, Vi̇cdan Köksaldi Motor, Ayşe Nedret Koç, Yüsüf Önlen, Çeti̇n Kilinç, Süleyman Durmaz
Investigations Of Als1 And Hwp1 Genes In Clinical Isolates Of Candida Albicans, Melek İnci̇, Mustafa Altay Atalay, Burçi̇n Özer, Ömer Evi̇rgen, Ni̇zami̇ Duran, Vi̇cdan Köksaldi Motor, Ayşe Nedret Koç, Yüsüf Önlen, Çeti̇n Kilinç, Süleyman Durmaz
Turkish Journal of Medical Sciences
To explore the presence of ALS1 and HWP1 genes by multiplex polymerase chain reaction (PCR) in Candida albicans strains. Materials and methods: By using the multiplex PCR method, the presence of agglutinin-like sequence 1 (ALS1) and hyphal wall protein 1 (HWP1) genes were investigated in 206 C. albicans strains that were isolated from various clinical samples. Phenotypic identification of slime formation by microplate and tube adherence tests was performed. Results: The presence of the ALS1 gene was detected in 53.9% of all strains, while the HWP1 gene was present in 5.3%. Slime formation was phenotypically detected in the 62.2% of …
The Effects Of Antioxidants On Testicular Apoptosis And Oxidative Stress Produced By Cell Phones, Aki̇f Koç, Doğan Ünal, Ersi̇n Çi̇mentepe, Ömer Bayrak, Ömer Faruk Karataş, Mehmet Erol Yildirim, Reyhan Bayrak, Murat Aydin
The Effects Of Antioxidants On Testicular Apoptosis And Oxidative Stress Produced By Cell Phones, Aki̇f Koç, Doğan Ünal, Ersi̇n Çi̇mentepe, Ömer Bayrak, Ömer Faruk Karataş, Mehmet Erol Yildirim, Reyhan Bayrak, Murat Aydin
Turkish Journal of Medical Sciences
The aim of this study was to determine the probable effects of cellular phone usage on apoptosis and oxidative/antioxidative balance in testicular tissue, and the probable protective role of vitamin C and E on these processes. Materials and methods: Forty-two male rats were divided into 6 groups: control, antioxidant, calling, stand-by, calling plus antioxidant, and stand-by plus antioxidant. Oxidant and antioxidant parameters and apoptotic indexes were studied. Two identical cell phones were used in the calling and stand-by groups. Results: Cell phone usage significantly increased apoptosis in call, but not in the stand-by position, in testicular tissue. Apoptosis produced in …
Analysis Of 161 Adult Patients With Brucellosis, Bi̇rcan Kayaaslan, Esragül Akinci, Ali̇ye Baştuğ, Seli̇m Sirri Eren, Pinar Öngürü, Ayşe But, Meltem Arzu Yetki̇n, Hurrem Bodur
Analysis Of 161 Adult Patients With Brucellosis, Bi̇rcan Kayaaslan, Esragül Akinci, Ali̇ye Baştuğ, Seli̇m Sirri Eren, Pinar Öngürü, Ayşe But, Meltem Arzu Yetki̇n, Hurrem Bodur
Turkish Journal of Medical Sciences
To evaluate the epidemiology, clinical features, and complications of brucellosis. Materials and methods: Between January 2005 and December 2008, 161 patients with brucellosis who were admitted to our clinic were evaluated prospectively. Results: Of the patients, 97 (60.2%) were male, and the mean age was 47 ± 17 years (range: 16-79). There were 99 patients (61.5%) classified as acute, 36 (22.4%) classified as subacute, and 6 (3.7%) classified as having a chronic infection. Relapse or reinfection was observed in 20 (12.4%) patients. Blood culture positivity rates were 60.7% and 44.8% among acute and subacute cases, respectively (P = 0.008). In …
Is Placement Of Pelvic Drain Indispensable After Radical Cystectomy, Extended Lymph Node Dissection, And Orthotopic Neobladder Substitution?, Ahmet Tunç Özdemi̇r, Serkan Altinova, Ege Can Şerefoğlu, Ali̇ Fuat Atmaca, Mevlana Derya Balbay
Is Placement Of Pelvic Drain Indispensable After Radical Cystectomy, Extended Lymph Node Dissection, And Orthotopic Neobladder Substitution?, Ahmet Tunç Özdemi̇r, Serkan Altinova, Ege Can Şerefoğlu, Ali̇ Fuat Atmaca, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
To evaluate the necessity of leaving a pelvic drain after open radical cystectomy. Materials and methods: Between January 2007 and January 2010, 58 patients with muscle-invasive bladder carcinoma were included. All patients underwent radical cystectomy, extended lymph node dissection, and orthotopic bladder (Studer pouch) substitution. Patients were randomized to have a pelvic drain catheter (Group 1, n = 22) or not (Group 2, n = 36). Ureteral catheters were removed at postoperative days 7 and 8. The pelvic drain catheters in Group 1 were removed when daily production was
The Effects Of Short-Acting Analogue Insulins On Body Weight In Patients With Type 2 Diabetes Mellitus, Cumali̇ Karatoprak, Servet Yolbaş, Muharrem Kiskaç, Mehmet Zorlu, Adnan Yay, Mustafa Çakirca, Mehmetali̇ Çikrikçioğlu, Reha Erkoç, Ertuğrul Taşan
The Effects Of Short-Acting Analogue Insulins On Body Weight In Patients With Type 2 Diabetes Mellitus, Cumali̇ Karatoprak, Servet Yolbaş, Muharrem Kiskaç, Mehmet Zorlu, Adnan Yay, Mustafa Çakirca, Mehmetali̇ Çikrikçioğlu, Reha Erkoç, Ertuğrul Taşan
Turkish Journal of Medical Sciences
To investigate the effects of short-acting analogue insulins on weight, and to demonstrate the difference between analogues. Materials and methods: Our study included patients who have used only intensive insulin therapy with metformin. Those who took other oral antidiabetics, other insulin derivatives, or different insulin combinations were excluded from the study because of the adverse effects on patients' weights. Results: Our study included 118 patients who used insulin glargine with short-acting analogue insulins, i.e. insulin aspart (38 patients), insulin lispro (28 patients), and insulin glulisine (52 patients). After 3 to 6 months of treatment, significant weight gain was observed in …
Anterior Segment Morphometry And Intraocular Pressure Change After Uneventful Phacoemulsification, Tamer Takmaz, Pinar Kösekahya, Pi̇raye Zeynep Kürkçüoğlu
Anterior Segment Morphometry And Intraocular Pressure Change After Uneventful Phacoemulsification, Tamer Takmaz, Pinar Kösekahya, Pi̇raye Zeynep Kürkçüoğlu
Turkish Journal of Medical Sciences
To evaluate the changes in anterior segment morphometry and intraocular pressure (IOP) with 3D rotating Scheimpflug camera-topography system after uneventful phacoemulsification. Materials and methods: In 56 eyes of 54 patients, anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), and central corneal thickness (CCT) were measured with the Sirius 3D Rotating Scheimpflug camera-topography system preoperatively and 1 month after surgery. IOP was measured with applanation tonometer. The preoperative and postoperative results were compared. Results: Preoperative and postoperative anterior segment parameters were as follows: ACD 2.7 ± 0.4 and 3.5 ± 0.3 mm, ACV 143.6 ± 48.8 and …
Comparison Of Latanoprost, Brimonidine Tartrate, And Bimatoprost Plus Timolol Maleate In Fixed Combinations, Güli̇z Fatma Yavaş, Tuncay Küsbeci̇, Onur Polat, Mahmut Karadaş, Sitki Samet Ermi̇ş, Ümi̇t Übeyt İnan
Comparison Of Latanoprost, Brimonidine Tartrate, And Bimatoprost Plus Timolol Maleate In Fixed Combinations, Güli̇z Fatma Yavaş, Tuncay Küsbeci̇, Onur Polat, Mahmut Karadaş, Sitki Samet Ermi̇ş, Ümi̇t Übeyt İnan
Turkish Journal of Medical Sciences
To compare the intraocular pressure (IOP)-lowering efficacy of fixed-combination antiglaucoma agents, and to evaluate the effect of these drugs on the visual field and optic disk morphology. Materials and methods: Included in this retrospective study were 17 eyes receiving latanoprost 0.005% + timolol maleate 0.5% fixed combination (group 1), 18 eyes receiving brimonidine tartrate 0.2% + timolol maleate 0.5% fixed combination (group 2), and 16 eyes receiving bimatoprost 0.03% + timolol maleate 0.5% fixed combination (group 3), all with the diagnosis of primary open-angle glaucoma or ocular hypertension. Intraocular pressure was measured by Goldmann applanation tonometer, a visual field test …
Immunohistochemical Distribution And Gene Expression Of Transforming Growth Factor Alpha In Ovarian Tissue Of Rats Treated With Capsaicin In Puberty, Sevda Eli̇ş Yildiz, Mümtaz Nazli, Gökhan Nur
Immunohistochemical Distribution And Gene Expression Of Transforming Growth Factor Alpha In Ovarian Tissue Of Rats Treated With Capsaicin In Puberty, Sevda Eli̇ş Yildiz, Mümtaz Nazli, Gökhan Nur
Turkish Journal of Medical Sciences
In this study, the effects of capsaicin on the immunohistochemical distribution and gene expression of transforming growth factor alpha (TGF-\alpha) in ovarian tissue of rats at the pubertal age were examined. Materials and methods: Rats (50 days old) were divided into experimental, alimentation, and sham groups. The experimental group was injected with 1 mg/kg doses of capsaicin (10% ethanol and 1% Tween in an 80% distilled water mixture) subcutaneously every day for a period of 1 week. The alimentation group received 1 mg/kg doses of capsaicin (10% ethanol and 1% Tween in an 80% distilled water mixture). The sham group …
Serum Lipoprotein(A) And High Sensitivity C Reactive Protein Levels In Saudi Patients With Type 2 Diabetes Mellitus And Their Relationship With Glycemic Control, Syed Shahid Habib
Serum Lipoprotein(A) And High Sensitivity C Reactive Protein Levels In Saudi Patients With Type 2 Diabetes Mellitus And Their Relationship With Glycemic Control, Syed Shahid Habib
Turkish Journal of Medical Sciences
To study serum lipoprotein(a) [Lp(a)] and high sensitivity C reactive protein (hsCRP) levels in Saudi patients with type 2 diabetes mellitus (DM) and their relationship with glycemic control. Materials and methods: A total of 201 subjects were selected for the study. The final selection included 103 patients with type 2 DM (64 males and 39 females) and 98 healthy control subjects (58 males and 40 females). Fasting venous blood samples were analyzed for glucose, glycosylated hemoglobin (HbA1c), lipids, Lp(a), and hsCRP levels. Results: Subjects with poor glycemic control showed significantly higher levels of fasting blood glucose levels (10.29 ± 3.56 …
Primary Lung Adenoid Cystic Carcinoma: A Case Report And Review Of The Literature, Şule Kaya, Müni̇re Çakir
Primary Lung Adenoid Cystic Carcinoma: A Case Report And Review Of The Literature, Şule Kaya, Müni̇re Çakir
Turkish Journal of Medical Sciences
Adenoid cystic carcinoma (ACC) is a rare low-grade malignant epithelial tumor that usually originates in the salivary glands. It shows a slow progression and metastasizes rarely. A 74-year-old male patient was admitted to our clinic due to pulmonary lesions seen on a chest-X ray coincidentally. The patient, 6 years before admission, was operated on for a peptic ulcer perforation and a right hilar mass lesion, and bibasilar pulmonary nodular lesions were also found on his chest radiograph. A bronchoscopic biopsy revealed ACC and surgical treatment was offered to the patient; however, he refused it. The patient, who had a 130-pack-year …
A Multicenter Study Of The Application Of Six Sigma Management In Clinical Rational Drug Use Via Pharmacist Intervention, Lidao Bao, Nan Chen, Tao Shang, Puyan Fang, Zhanping Xu, Wenchang Guo, Yi Wang
A Multicenter Study Of The Application Of Six Sigma Management In Clinical Rational Drug Use Via Pharmacist Intervention, Lidao Bao, Nan Chen, Tao Shang, Puyan Fang, Zhanping Xu, Wenchang Guo, Yi Wang
Turkish Journal of Medical Sciences
The status of outpatient irrational prescription drug use before and after pharmacist interventions in 6 large scale hospitals was investigated to determine the underlying reasons and to promote rational clinical drug use. Materials and methods: The 5-step DMAIC method (define, measure, analyze, improve, control) in Six Sigma management was utilized to investigate irrational drug use in prescriptions. The statistical software package SAS9.1.3 was adopted to analyze the results, determine possible reasons that could lead to irrational drug use, and then intervene accordingly. Statistics before and after the intervention were compared to analyze the function and effect of Six Sigma management …
Rapid Identification Of Aeromonas Species In Stool Samples With Chromogenic Media And Matrix-Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry: An Institutional Experience, Işin Akyar, Si̇mge Can
Rapid Identification Of Aeromonas Species In Stool Samples With Chromogenic Media And Matrix-Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry: An Institutional Experience, Işin Akyar, Si̇mge Can
Turkish Journal of Medical Sciences
To evaluate the routine use of chromogenic media together with matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) in gastrointestinal infections caused by Aeromonas spp. as rapid, practical, cost-effective and reliable methods. Materials and methods: Between August 2007 and March 2012, a total of 13,194 stool specimens of patients were included in the study. The stool samples and the reference strains were inoculated onto Cefsulodin-Irgasan-Novobiocin agar, sheep blood agar, eosin-methylene blue agar, and Hektoen enteric agar media together with CHROMagar Salmonella Plus. All the Salmonella and Aeromonas suspected colonies were identified with an automated system (Phoenix) and MALDI-TOF. Results: …
Does Adma Affect The Oxidant/Antioxidant Balance In Rats?, Hasan Alaçam, Bahatti̇n Avci, Osman Şaliş, Ahmet Di̇lek, Ahmet Kozan, Cuma Mertoğlu, Mehmet Şahi̇n, Ali̇ Okuyucu
Does Adma Affect The Oxidant/Antioxidant Balance In Rats?, Hasan Alaçam, Bahatti̇n Avci, Osman Şaliş, Ahmet Di̇lek, Ahmet Kozan, Cuma Mertoğlu, Mehmet Şahi̇n, Ali̇ Okuyucu
Turkish Journal of Medical Sciences
Asymmetric dimethylarginine (ADMA) is an inhibitor of nitric oxide synthase (NOS). Oxidative stress might be defined as an imbalance between protein oxidation and antioxidants. Our aim was to determine in vivo whether ADMA causes oxidative damage. Materials and methods: Thirty rats were divided into 3 equal groups: a control group, a group administered 1 mg/kg ADMA, and a group administered 2 mg/kg ADMA. ADMA was administered intraperitoneally for 7 days. Malondialdehyde (MDA), protein carbonyl (PC) content, and nitrate+nitrite concentrations were measured with serum samples. Superoxide dismutase (SOD), catalase, and glutathione peroxidase (GSH-Px) activities were analyzed with plasma samples. Results: A …
Endovenous Laser Ablation For Saphenous Vein Insufficiency: Long-Term Results, Ömer Etli̇k, Aşkin Ali̇ Korkmaz, Yeşi̇m Üçkurt, Sevi̇m İndelen, Recep Gündoğdu, Alaatti̇n Öztürk, Sali̇h Alsalehi̇, Soe Moe Aung
Endovenous Laser Ablation For Saphenous Vein Insufficiency: Long-Term Results, Ömer Etli̇k, Aşkin Ali̇ Korkmaz, Yeşi̇m Üçkurt, Sevi̇m İndelen, Recep Gündoğdu, Alaatti̇n Öztürk, Sali̇h Alsalehi̇, Soe Moe Aung
Turkish Journal of Medical Sciences
To present the long-term results of our 158 endovenous laser ablation (EVLA) procedures. Materials and methods: From June 2008 to December 2011, 158 patients (89 women, 69 men; mean age: 38.2 years, range: 27-65) were treated with EVLA for venous insufficiency in 192 lower limbs. All patients were symptomatic and the majority had a class 4 or higher clinical disease (CEAP classification). A 980-nm diode laser was used under general anesthesia combined with local tumescent anesthesia to deliver 100 to 140 laser applications along the course of the vein. Compression bandages were applied for 2 weeks postoperatively. Follow-up exams were …
An Alternative Method Of Oral To Nasal Endotracheal Intubation In Patients Undergoing Maxillofacial Surgery, Hasan Kutluk Pampal, Meti̇n Alkan, Cengi̇z Beki̇r Demi̇rel, Gökçen Emmez, Nurdan Bedi̇rli̇
An Alternative Method Of Oral To Nasal Endotracheal Intubation In Patients Undergoing Maxillofacial Surgery, Hasan Kutluk Pampal, Meti̇n Alkan, Cengi̇z Beki̇r Demi̇rel, Gökçen Emmez, Nurdan Bedi̇rli̇
Turkish Journal of Medical Sciences
Patients undergoing maxillofacial surgery frequently require nasal intubation. Although awake fiberoptic intubation is the procedure of choice, a fiberoptic bronchoscope (FOB) may not be available in all clinics. Furthermore, the procedure itself requires skill and experience, and cannot be used when the view is obstructed by bleeding or secretions. Herein we describe 3 patients in whom oral to nasal endotracheal tube exchange was accomplished with the aid of a nasogastric tube after placement of an LMA CTrachTM, as no FOB was available.
Urease Inhibitory Potential Of Zizyphus Oxyphylla Edgew. Extracts And Isolated Compounds, Waqar Ahmad Kaleem, Muhammad Nisar, Mughal Qayum, Muhammad Zia-Ul-Haq, Muhammad Iqbal Choudhary, Sezai̇ Erci̇şli̇
Urease Inhibitory Potential Of Zizyphus Oxyphylla Edgew. Extracts And Isolated Compounds, Waqar Ahmad Kaleem, Muhammad Nisar, Mughal Qayum, Muhammad Zia-Ul-Haq, Muhammad Iqbal Choudhary, Sezai̇ Erci̇şli̇
Turkish Journal of Medical Sciences
To determine the urease inhibitory potential of extracts and isolated compounds from Zizyphus oxyphylla Edgew. Materials and methods: Methanolic extracts and subsequent fractions of Z. oxyphylla stem and 3 isolated compounds from the roots of Z. oxyphylla were obtained through column chromatography and subjected to in vitro urease inhibition. Results: Three fractions (n-hexane, ethyl acetate, and butanol fractions) showed good to excellent activity, while the chloroform fraction showed nonsignificant activity. Amongst the isolated compounds, oxyphylline D (1) was the most active of the 3 isolated cyclopeptide alkaloids, followed by nummularin R (3) and nummularin C (2). Conclusion: Z. oxyphylla has …
Pcr Detection Of Brucella Abortus In Cow Milk Samples Collected From Erzurum, Turkey, Tüli̇n Arasoğlu, Medi̇ne Güllüce, Hakan Özkan, Ahmet Adigüzel, Fi̇kretti̇n Şahi̇n
Pcr Detection Of Brucella Abortus In Cow Milk Samples Collected From Erzurum, Turkey, Tüli̇n Arasoğlu, Medi̇ne Güllüce, Hakan Özkan, Ahmet Adigüzel, Fi̇kretti̇n Şahi̇n
Turkish Journal of Medical Sciences
In this study, we designed and used 2 different type-specific polymerase chain reaction (PCR) methods for the detection of Brucella abortus. Materials and methods: There were 2 different primer sets (B4/B5 and AF/AR) selected and used for the amplification of 2 different genes that are present in all biovars of Brucella species, including bcsp31, encoding 31-kDa immunogenic cell surface proteins, and omp25, which is known to be one of the virulence factors encoding outer membrane proteins of 26–23 kDa. Results: The results showed that 273 (81.7%) and 317 (94.9%) out of 334 milk samples were positive for brucellosis, as detected …
Epidemiology, Clinical Features, And Laboratory Detection Of Mycoplasma Pneumoniae Infection In East Azerbaijan, Iran, Reza Ghotaslou, Simin Sharifi, Mohammad Taghi Akhi, Mohammad Hossein Soroush
Epidemiology, Clinical Features, And Laboratory Detection Of Mycoplasma Pneumoniae Infection In East Azerbaijan, Iran, Reza Ghotaslou, Simin Sharifi, Mohammad Taghi Akhi, Mohammad Hossein Soroush
Turkish Journal of Medical Sciences
Mycoplasma pneumoniae is involved in the etiology of many respiratory tract infections. This prospective study describes the epidemiology and clinical properties of M. pneumoniae infections in hospitals of the Tabriz University of Medical Sciences. Materials and methods: From May 2009 to November 2010, 200 patients with respiratory tract infections were enrolled into this study. Due to antibiotic use 51 patients were excluded. M. pneumoniae from respiratory infections was detected by culture, enzyme-linked immunosorbent assay (ELISA), and polymerase chain reaction (PCR) assays. Results: M. pneumoniae infection was detected in 9 (6.15%), 8 (5.3%), and 3 (2.01%) of patients by PCR, ELISA, …
The Effect Of Addition Of Lidocaine To Bupivacaine On Anesthesia Beginning Time, Block Time, And Block Quality In Lateral Sagittal Infraclavicular Block, Özgür Özmen, Haci Ahmet Alici, Mi̇ne Çeli̇k, Ayşenur Dostbi̇l, Mehmet Cesur
The Effect Of Addition Of Lidocaine To Bupivacaine On Anesthesia Beginning Time, Block Time, And Block Quality In Lateral Sagittal Infraclavicular Block, Özgür Özmen, Haci Ahmet Alici, Mi̇ne Çeli̇k, Ayşenur Dostbi̇l, Mehmet Cesur
Turkish Journal of Medical Sciences
To investigate whether a 2% lidocaine addition to 0.5% bupivacaine that is used in a lateral sagittal infraclavicular block, when administered in an upper extremity surgery, decreases the block onset time, drug effect time, and drug activity when compared with bupivacaine alone. Materials and methods: This study was performed on 120 American Society of Anesthesiology classification I-II patients who were 18–65 years old and scheduled to undergo an upper extremity surgery. The group testing in the study was as follows: 20 mL (5 mg/mL) bupivacaine, 10 mL (5 mg/mL) bupivacaine + 10 mL (20 mg/mL) lidocaine, and 20 mL (20 …
Antimicrobial Susceptibilities Of Various Arcobacter Species, Ahmet Ünver, Hali̇l İbrahi̇m Atabay, Mi̇tat Şahi̇n, Özgür Çelebi̇
Antimicrobial Susceptibilities Of Various Arcobacter Species, Ahmet Ünver, Hali̇l İbrahi̇m Atabay, Mi̇tat Şahi̇n, Özgür Çelebi̇
Turkish Journal of Medical Sciences
To determine the antimicrobial susceptibilities of various Arcobacter strains isolated from domestic geese, which have great potential for the transmission of arcobacters to humans and animals by contamination of water sources. Materials and methods: A total of 16 Arcobacter strains including A. cryaerophilus (7), A. skirrowii (7), and A. butzleri (2) were examined for their susceptibilities to 20 antibiotics using a disk-diffusion method. Results: All Arcobacter isolates tested were resistant to cloxacillin, cefazolin, optochin, vancomycin, and fusidic acid, and most were susceptible to oxytetracycline, chloramphenicol (except for A. butzleri), nitrofurantoin, amikacin, enrofloxacin, ofloxacin, erythromycin, ampicillin sulbactam, and amoxicillin (except for …
Cytokine Associated Neopterin Response Of Peripheral Blood Mononuclear Cells To In Vitro Epstein–Barr Virus Transformation Process Of B Lymphocytes, Lati̇fe Arzu Aral, Ayşegül Atak Yücel
Cytokine Associated Neopterin Response Of Peripheral Blood Mononuclear Cells To In Vitro Epstein–Barr Virus Transformation Process Of B Lymphocytes, Lati̇fe Arzu Aral, Ayşegül Atak Yücel
Turkish Journal of Medical Sciences
The Epstein-Barr Virus (EBV) is a human herpes virus that infects B lymphocytes latently and immortalises the cells due to transformation. EBV infection is asymptomatic in childhood, while it may cause a self-limiting lymphoproliferative disorder in adolescence. This study aimed to show the association between in vitro transformation of B lymphocytes via EBV and the levels of neopterin with different accompanying cytokine responses. Materials and methods: Mononuclear cells were isolated from peripheral blood samples of healthy donors and transformed with an EBV secreting cell-line, B95-8. Neopterin, interferon (IFN)-\gamma, tumour necrosis factor (TNF)-\alpha, and interleukin (IL)-6 levels were measured in culture …
Renal Bcl-2/Bax Expression In Childhood Henoch-Schönlein Nephritis: Prognostic Importance?, Kenan Bek, Ayşegül Oksal, Gülay Demi̇rci̇n, Mehmet Bülbül, Özlem Aydoğ, Ali̇ Deli̇baş, Ayşe Öner
Renal Bcl-2/Bax Expression In Childhood Henoch-Schönlein Nephritis: Prognostic Importance?, Kenan Bek, Ayşegül Oksal, Gülay Demi̇rci̇n, Mehmet Bülbül, Özlem Aydoğ, Ali̇ Deli̇baş, Ayşe Öner
Turkish Journal of Medical Sciences
To investigate the renal expression of apoptosis regulatory proteins b-cell lymphoma 2 (bcl-2) and bcl-2 associated X (bax) in children with Henoch–Schönlein nephritis (HSN) Materials and methods: Renal expression of antiapoptotic bcl-2 and proapoptotic bax proteins were studied immunohistochemically in 22 children with HSN. The kidneys of 5 children who died due to nonrenal reasons were used as the control. The patients were compared according to their renal histopathology and prognosis. Results: Nephrotic or nephrotic-nephritic renal involvement was the most common presentation. Histopathological findings were Class I in 1, Class II in 5, Class III in 10, Class IV in …
Diagnostic Value Of Cytokeratin 19, Hbme-1, And Galectin-3 Immunostaining Of Cell Block From Fine-Needle Aspiration Specimens In Papillary Carcinoma Of The Thyroid, Hacer Haltaş, Reyhan Bayrak, Si̇bel Yeni̇dünya, Ümran Yildirim
Diagnostic Value Of Cytokeratin 19, Hbme-1, And Galectin-3 Immunostaining Of Cell Block From Fine-Needle Aspiration Specimens In Papillary Carcinoma Of The Thyroid, Hacer Haltaş, Reyhan Bayrak, Si̇bel Yeni̇dünya, Ümran Yildirim
Turkish Journal of Medical Sciences
To evaluate the utility of immunohistochemical staining of cytokeratin 19 (CK19), HBME-1, and galectin-3 in cell block preparations of fine-needle aspiration cytology specimens as ancillary techniques for the differential diagnosis of papillary thyroid carcinoma. Materials and methods: Immunohistochemical detection of CK19, HBME-1, and galectin-3 was completed in 45 thyroid aspiration cytology specimens fixed in paraffin-embedded blocks consisting of the following cytologic diagnoses: 1) 16 cases of papillary carcinoma, 2) 16 cases suspicious for papillary carcinoma, and 3) 13 cases involving nonneoplastic lesions. Results: The follicular cells in the cytologically unequivocal papillary carcinoma diagnosis group expressed diffusely positive (+++) CK19, HBME-1, …
Determining The Association Between Turkish Women’S Menopausal Symptoms And Their Marital Adjustment, Asli Si̇s Çeli̇k, Türkan Pasi̇nli̇oğlu
Determining The Association Between Turkish Women’S Menopausal Symptoms And Their Marital Adjustment, Asli Si̇s Çeli̇k, Türkan Pasi̇nli̇oğlu
Turkish Journal of Medical Sciences
To determine the association between women's menopausal symptoms and their marital adjustment. Materials and methods: A descriptive cross-sectional study was conducted on 263 Turkish women chosen using an improbable randomized sampling method. A questionnaire, the Menopause Symptom Rating Scale (MSRS), and the Dyadic Adjustment Scale (DAS) were used to collect data. Percentage distributions, the t-test in independent groups, the one-way ANOVA test, Pearson correlation analysis, and the Kruskal-Wallis test were used in the evaluation of the data. Results: The mean of the overall MSRS score for women was 22.67 ± 8.06 and the mean of the overall DAS score for …
The Expression Of Cell Adhesion Molecules In Colorectal Cancer Tissue And Its Clinical Values, Dong Chen, Huiying Zhao, Feng Ye
The Expression Of Cell Adhesion Molecules In Colorectal Cancer Tissue And Its Clinical Values, Dong Chen, Huiying Zhao, Feng Ye
Turkish Journal of Medical Sciences
To investigate the role of cell adhesion molecules CD44v6 and CEA in the occurrence, development, and metastasis of colorectal cancer (CRC). Materials and methods: The expression of CD44v6 and CEA in 76 CRC tissues and 43 normal colon tissues was detected using an immunohistological technique. The relationship between the 2 molecules’ expression and their pathologic characteristics, especially for metastasis, was investigated. Furthermore, the relevance between the expression of CD44v6 and of CEA was also assessed. Results: Expression of CD44v6 and CEA protein in CRC tissues was higher than in paracarcinoma tissue and normal colorectal mucosa (both P < 0.001). Positive expression of CD44v6 in CRC was associated with lymph node metastasis, Dukes’ stage, and histological differentiation. Higher expression intensity of CEA in CRC was related to lymph node involvement, distant metastasis, and invasion depth. Combining analysis of CD44v6 and CEA can improve the sensitivity and specificity in evaluating the metastatic potential of CRC (P < 0.05). There was no relevance between the expression of CD44v6 and CEA in CRC (P > 0.05). Conclusion: CD44v6 …
Influence Of Trace Elements And Their Correlation With Semen Quality In Fertile And Infertile Subjects, Vickram Sundaram, Muthugadhalli Srinivas, Jayaraman Gurunathan, Kamini Rao, Ramesh Pathy Maniyan, Sridharan Balasundaram
Influence Of Trace Elements And Their Correlation With Semen Quality In Fertile And Infertile Subjects, Vickram Sundaram, Muthugadhalli Srinivas, Jayaraman Gurunathan, Kamini Rao, Ramesh Pathy Maniyan, Sridharan Balasundaram
Turkish Journal of Medical Sciences
There has been increasing curiosity about the appraisal of essential trace elements present in human body fluids and their correlation to human health. Human seminal plasma contains several trace elements that have an imperative role in the normal functioning of the semen. As a result, it is very important to evaluate Zn and other trace elements present in the seminal plasma for the assessment of male infertility. The main objective of this research is to evaluate Zn concentrations and their intercorrelations with semen parameters such as sperm concentration, sperm motility, and normal morphology of the sperm, towards their contribution to …
Retrospective Evaluation Of 104 Tinea Capitis Cases, Ömer Çalka, Serap Güneş Bi̇lgi̇li̇, Ayşe Serap Karadağ, Sevda Önder
Retrospective Evaluation Of 104 Tinea Capitis Cases, Ömer Çalka, Serap Güneş Bi̇lgi̇li̇, Ayşe Serap Karadağ, Sevda Önder
Turkish Journal of Medical Sciences
Tinea capitis is a superficial scalp dermatophyte infection. Tinea capitis is particularly seen during childhood and is not usually seen after puberty. In untreated cases, it can be contagious and can progress to cicatricial alopecia. This study aimed to retrospectively evaluate cases of tinea capitis. Materials and methods: We evaluated 104 tinea capitis patients presenting to our dermatology clinic between 2007 and 2011. Results: Of these patients, 38 (36.5%) were female and 66 (63.5%) were male. The median age was 6.41 ± 3.4 years (range: 1-18 years old). The clinical types appearing in descending order were tinea capitis profunda (88.5%), …