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Evaluation Of The Effects Of Desflurane And Sevoflurane Anesthesia On Alveolar Epithelial Permeability By Tc-99m Dtpa Inhalation Scintigraphy, Abdulkadi̇r İskender, Meli̇h Engi̇n Erkan, Mesut Erbaş, Damla Güçlü Güven, Gülbi̇n Sezen, Muhammet Aşik, Yavuz Demi̇raran, Mustafa Yildirim
Evaluation Of The Effects Of Desflurane And Sevoflurane Anesthesia On Alveolar Epithelial Permeability By Tc-99m Dtpa Inhalation Scintigraphy, Abdulkadi̇r İskender, Meli̇h Engi̇n Erkan, Mesut Erbaş, Damla Güçlü Güven, Gülbi̇n Sezen, Muhammet Aşik, Yavuz Demi̇raran, Mustafa Yildirim
Turkish Journal of Medical Sciences
Recently studies showed that volatile anesthetics affect the ciliary beat frequency in vitro. We know that impairment of ciliary beat frequency is related to a risk of pulmonary complications with general anesthesia. Other studies have also shown that exposure to a volatile anesthetic can increase the permeability of the alveolar–capillary barrier. The present study aimed to determine the effects of desflurane and sevoflurane anesthesia on the technetium-labeled diethylene triamine penta-acetic acid (Tc-99m DTPA) clearance rate of the alveolar epithelium. Materials and methods: A total of 40 patients who underwent elective tympanoplasty with general anesthesia were included in this study. Patients …
Comparison Of The Protective Effects Of Desflurane And Propofol Anesthesia In Rats: A Hepatic Ischemia-Reperfusion Injury Model, Ayça Taş Tuna, Cengi̇z Beki̇r Demi̇rel, Yusuf Ünal, Aslihan Çavunt Bayraktar, Demet Yilmazer, Mustafa Kavutçu, Murat Alper, Mustafa Kerem
Comparison Of The Protective Effects Of Desflurane And Propofol Anesthesia In Rats: A Hepatic Ischemia-Reperfusion Injury Model, Ayça Taş Tuna, Cengi̇z Beki̇r Demi̇rel, Yusuf Ünal, Aslihan Çavunt Bayraktar, Demet Yilmazer, Mustafa Kavutçu, Murat Alper, Mustafa Kerem
Turkish Journal of Medical Sciences
It is known that desflurane and propofol protect liver tissue via different mechanisms. The aim of this study was to compare the protective effects of these 2 agents against hepatic ischemia-reperfusion injury. Materials and methods: Rats were randomly divided into 2 groups: ischemia and ischemia-reperfusion. Each group was further divided into 3 subgroups: ketamine, desflurane, and propofol. Thirty minutes after anesthetics were administered, the rats were subjected to 45 min of hepatic ischemia and 4 h of reperfusion. Blood samples and liver tissues were obtained in order to assess serum tumor necrosis factor alpha (TNF-\alpha), interleukin-1\beta (IL-1\beta), and malondialdehyde levels …