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Full-Text Articles in Medicine and Health Sciences
Renal Bcl-2/Bax Expression In Childhood Henoch-Schönlein Nephritis: Prognostic Importance?, Kenan Bek, Ayşegül Oksal, Gülay Demi̇rci̇n, Mehmet Bülbül, Özlem Aydoğ, Ali̇ Deli̇baş, Ayşe Öner
Renal Bcl-2/Bax Expression In Childhood Henoch-Schönlein Nephritis: Prognostic Importance?, Kenan Bek, Ayşegül Oksal, Gülay Demi̇rci̇n, Mehmet Bülbül, Özlem Aydoğ, Ali̇ Deli̇baş, Ayşe Öner
Turkish Journal of Medical Sciences
To investigate the renal expression of apoptosis regulatory proteins b-cell lymphoma 2 (bcl-2) and bcl-2 associated X (bax) in children with Henoch–Schönlein nephritis (HSN) Materials and methods: Renal expression of antiapoptotic bcl-2 and proapoptotic bax proteins were studied immunohistochemically in 22 children with HSN. The kidneys of 5 children who died due to nonrenal reasons were used as the control. The patients were compared according to their renal histopathology and prognosis. Results: Nephrotic or nephrotic-nephritic renal involvement was the most common presentation. Histopathological findings were Class I in 1, Class II in 5, Class III in 10, Class IV in …
Assessment Of Immune Responses To Hepatitis A Vaccination In Children Aged 1 And 2 Years, Solmaz Çelebi̇, Mustafa Kemal Hacimustafaoğlu, Yücehan Albayrak, Ayşe Melda Sinirtaş
Assessment Of Immune Responses To Hepatitis A Vaccination In Children Aged 1 And 2 Years, Solmaz Çelebi̇, Mustafa Kemal Hacimustafaoğlu, Yücehan Albayrak, Ayşe Melda Sinirtaş
Turkish Journal of Medical Sciences
Hepatitis A can be prevented by vaccination. The aim of this study was to determine seropositivity for hepatitis A before vaccination in healthy children 12 and 24 months of age and compare seroconversion rates after vaccination between these 2 groups. Materials and methods: Forty-nine children aged 1 year (Group 1) and 51 children aged 2 years (Group 2) were included in the study. Inactive hepatitis A vaccine (Avaxim, 80 antigenic subtypes, 0.5 mL) were administered to every child in 2 doses, 6 months apart. Anti-hepatitis A virus (HAV) IgG and IgM antibodies were detected by Architect HAVAb-IgG and HAVAb-IgM (Abbott, …