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Full-Text Articles in Medicine and Health Sciences
The Effects Of Antioxidants On Testicular Apoptosis And Oxidative Stress Produced By Cell Phones, Aki̇f Koç, Doğan Ünal, Ersi̇n Çi̇mentepe, Ömer Bayrak, Ömer Faruk Karataş, Mehmet Erol Yildirim, Reyhan Bayrak, Murat Aydin
The Effects Of Antioxidants On Testicular Apoptosis And Oxidative Stress Produced By Cell Phones, Aki̇f Koç, Doğan Ünal, Ersi̇n Çi̇mentepe, Ömer Bayrak, Ömer Faruk Karataş, Mehmet Erol Yildirim, Reyhan Bayrak, Murat Aydin
Turkish Journal of Medical Sciences
The aim of this study was to determine the probable effects of cellular phone usage on apoptosis and oxidative/antioxidative balance in testicular tissue, and the probable protective role of vitamin C and E on these processes. Materials and methods: Forty-two male rats were divided into 6 groups: control, antioxidant, calling, stand-by, calling plus antioxidant, and stand-by plus antioxidant. Oxidant and antioxidant parameters and apoptotic indexes were studied. Two identical cell phones were used in the calling and stand-by groups. Results: Cell phone usage significantly increased apoptosis in call, but not in the stand-by position, in testicular tissue. Apoptosis produced in …
Renal Bcl-2/Bax Expression In Childhood Henoch-Schönlein Nephritis: Prognostic Importance?, Kenan Bek, Ayşegül Oksal, Gülay Demi̇rci̇n, Mehmet Bülbül, Özlem Aydoğ, Ali̇ Deli̇baş, Ayşe Öner
Renal Bcl-2/Bax Expression In Childhood Henoch-Schönlein Nephritis: Prognostic Importance?, Kenan Bek, Ayşegül Oksal, Gülay Demi̇rci̇n, Mehmet Bülbül, Özlem Aydoğ, Ali̇ Deli̇baş, Ayşe Öner
Turkish Journal of Medical Sciences
To investigate the renal expression of apoptosis regulatory proteins b-cell lymphoma 2 (bcl-2) and bcl-2 associated X (bax) in children with Henoch–Schönlein nephritis (HSN) Materials and methods: Renal expression of antiapoptotic bcl-2 and proapoptotic bax proteins were studied immunohistochemically in 22 children with HSN. The kidneys of 5 children who died due to nonrenal reasons were used as the control. The patients were compared according to their renal histopathology and prognosis. Results: Nephrotic or nephrotic-nephritic renal involvement was the most common presentation. Histopathological findings were Class I in 1, Class II in 5, Class III in 10, Class IV in …
Protective Effect Of Vardenafil On Ischemia–Reperfusion Injury In Rat Ovary, Hati̇ce Baş, Özlem Kara, Mustafa Kara, Di̇lek Pandir
Protective Effect Of Vardenafil On Ischemia–Reperfusion Injury In Rat Ovary, Hati̇ce Baş, Özlem Kara, Mustafa Kara, Di̇lek Pandir
Turkish Journal of Medical Sciences
To investigate the effect of vardenafil on ischemia–reperfusion (I/R) injury in rat ovary. Materials and methods: A total of 21 Wistar rats were divided into 3 groups. In group 1, ovary torsion was not performed and no drug was administered. In group 2, 1 h of ischemia and 2 h of reperfusion were performed and no drug was given. In group 3, 1 h of ischemia and 2 h of reperfusion were performed and 1 mg/kg vardenafil was administered after 30 min of ischemia. Right ovaries were surgically removed in all groups. Malondialdehyde (MDA) levels and activities of superoxide dismutase …
Helicobacter Pylori Infection And Relationship With Gastric Epithelial Cell Proliferation And Apoptosis, Zühal Güci̇n, Tuğba Çakmak, Ni̇zametti̇n Bayyurt, Bari̇k Sali̇h
Helicobacter Pylori Infection And Relationship With Gastric Epithelial Cell Proliferation And Apoptosis, Zühal Güci̇n, Tuğba Çakmak, Ni̇zametti̇n Bayyurt, Bari̇k Sali̇h
Turkish Journal of Medical Sciences
To evaluate the effects of Helicobacter pylori on cell proliferation and apoptosis in gastric cancer (GC) both at tumoral and nontumoral sites and in gastritis. Materials and methods: Biopsies from 96 patients (gastric cancer = 52, gastritis = 44) were examined immunohistochemically and histopathologically. Results: In H. pylori-positive GC patients the average proliferative index (PI) in tumor and nontumor sites was 40.7% and 24.8%, while in H. pylori-negative patients it was 32.9% and 17.8%, respectively. The PI was significantly higher in the tumor than in the nontumor sites, regardless of H. pylori infection. Cell proliferation was also significantly associated with …
Influence Of Alpha Lipoic Acid On Epithelial Apoptosis In Experimental Periodontitis, Adem Kara, Sümeyra Akman, Tevfi̇k Demi̇rci̇, Taner Arabaci, Varol Çanakçi, Bünyami̇ Ünal
Influence Of Alpha Lipoic Acid On Epithelial Apoptosis In Experimental Periodontitis, Adem Kara, Sümeyra Akman, Tevfi̇k Demi̇rci̇, Taner Arabaci, Varol Çanakçi, Bünyami̇ Ünal
Turkish Journal of Medical Sciences
Alpha lipoic acid (ALA) is a powerful antioxidant. Its antiinflammatory effects and apoptotic mechanism have recently been studied in many diseases. This study aimed to investigate the effects of ALA on apoptotic activity in the treatment of periodontitis. Materials and methods: Thirty male Wistar rats were randomly divided into 3 groups: control (without ligature), PED (ligature + placebo, saline; oral gavage), and ALA+PED (ligature + alpha lipoic acid at 50 mg/kg/day in saline; oral gavage). Histological and biochemical analyses were performed on the mandibular first molars of sacrificed rats. Results: Biochemical myeloperoxidase activity in gingivo-mucosal tissue was measured. For immunohistochemical …