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Full-Text Articles in Medicine and Health Sciences
Effects Of Green Tea On Ace Gene Expression In Rat Liver In Ccl_4-Induced Cirrhosis, Syed Muhammad Shahid, Rozeena Shaikh, Sana Shamim, Muhammad Ismail, Tabassum Mahboob
Effects Of Green Tea On Ace Gene Expression In Rat Liver In Ccl_4-Induced Cirrhosis, Syed Muhammad Shahid, Rozeena Shaikh, Sana Shamim, Muhammad Ismail, Tabassum Mahboob
Turkish Journal of Medical Sciences
This study was designed to investigate the beneficial effects of green tea administration on angiotensin converting enzyme (ACE) gene expression in CCl_4-induced liver cirrhosis in rats. Materials and methods: A total of 24 male Wistar rats were divided into 3 groups as: Group 1, normal untreated rats; Group 2, CCl_4-induced cirrhotic rats; Group 3: CCl_4-induced cirrhotic + green tea treated rats. The beneficial effects of green tea were measured by alanine aminotransferase (ALT), alkaline phosphatase (ALP), total and direct bilirubin level, tissue malondialdehyde (MDA), super oxide dismutase (SOD), and catalase (CAT). The genomic DNA was isolated from excised tissue to …
No Major Impact Of Insertion/Deletion Polymorphism Of The Angiotensin-Converting Enzyme Gene On Thyroid-Associated Ophthalmopathy, Seydi̇ Okumuş, Şeni̇z Demi̇ryürek, Mehtap Özkur, Erol Coşkun, Mehmet Gürkan Tatar, İbrahi̇m Erbağci, Ersi̇n Akarsu
No Major Impact Of Insertion/Deletion Polymorphism Of The Angiotensin-Converting Enzyme Gene On Thyroid-Associated Ophthalmopathy, Seydi̇ Okumuş, Şeni̇z Demi̇ryürek, Mehtap Özkur, Erol Coşkun, Mehmet Gürkan Tatar, İbrahi̇m Erbağci, Ersi̇n Akarsu
Turkish Journal of Medical Sciences
To investigate the association between ACE gene I/D polymorphism and thyroid-associated ophthalmopathy (TO) in the Turkish population. Materials and methods: A total of 105 patients with TO and 102 healthy control subjects were enrolled in this case-control study. Genomic DNA was extracted from peripheral blood leukocytes, and I/D polymorphism of the ACE gene (ACE) was determined using a polymerase chain reaction. Results: There were no marked changes in allelic frequencies and genotype distribution of ACE I/D polymorphism between patients and control subjects. The distribution of I/D polymorphism and allele frequencies of TO patients were not significantly different from those of …