Physiology Commons^™

Is It Safe For Hemodialysis Patients To Seek Gains With Less Pain? Acute Hemodynamic Response To Intradialytic Blood Flow Restriction Training, Rony Nobre, Rodrigo Cardoso, Aline Araujo, Rafael Orcy, Jeniffer Aquino, Larissa Ribeiro, Rafaela Catto, Ana Carolina Conteratto, Airton Rombaldi, Maristela Bohlke

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 434-441, 2022. Considering that the hemodynamic safety is a major concern about intradialytic exercise with blood flow restriction, this analysis was performed to compare the blood pressure (BP) behavior during the first two hours of hemodialysis (HD) between sessions with no exercise (control group, CG), low/moderate intensity aerobic exercise with blood flow restriction (BFRE) and conventional aerobic exercise (AE). Adult patients with chronic kidney disease on HD at a university hospital were randomly assigned and submitted to a 12-week intradialytic training with BFRE or AE compared with the CG group. The main outcomes of …

Role Of Bmi1 In Acute Lung Injury, María Helena Hernández-Cuervo

USF Tampa Graduate Theses and Dissertations

Acute Lung Injury (ALI) is a set of signs and symptoms that lead to acute hypoxemic respiratory failure characterized by bilateral pulmonary infiltrates not attributed to cardiogenic origin. It is caused by a massive innate immune response, with the migration of white blood cells (neutrophils and macrophages principally) and a cytokine storm, followed by alterations in mitochondrial function, increase in reactive oxygen species production, and oxidative stress that in turn induces more mitochondrial damage. Several studies have shown that mitochondrial alterations are key events in the mechanism of ALI and reducing mitochondrial dysfunction could be a possible target in the …

Lifeguard Performance Skills: A Systematic Review, Paulo Santiago, Filipe Maia, Sandra Santiago, Daniel Duarte, Pedro Teques

International Journal of Aquatic Research and Education

Drowning is one of the leading causes of death worldwide and lifeguards’ action can be regarded as a significant contribution to change that reality. In this regard, the purpose of this systematic review was to identify factors associated with lifeguards’ performance. After extensive research on PsycArticles, PsicBooks, PsycInfo, SportDiscus, Web of Science, PubMed, Scopus and SportDiscus databases, containing the keywords “lifeguard” AND “performance”, “lifeguard” AND “skills” and “lifeguard” AND “drowning”, we obtained 429 research articles. After eliminating duplicates, excluding those that had no relevance to the study, and screening against set criteria, a total of five articles were fully reviewed. …

Temperature-Dependent Developmental Plasticity In The Cardiorespiratory System Of Atlantic Salmon, Carlie A. Muir

Electronic Thesis and Dissertation Repository

Anthropogenic climate change is expected to have pervasive impacts on the performance and viability of fishes, as increasing temperatures create aerobically constrained environments for many species. Given the rapid rates of projected temperature increases, it is critical to evaluate the capacity for fish to respond to a changing thermal environment through phenotypic plasticity. In this thesis, I examined the capacity for developmental plasticity in the thermal performance of juvenile Atlantic salmon (Salmo salar) reared under two thermal regimes from fertilization, and investigated potential mechanistic underpinnings within the cardiorespiratory system. Cardiac performance was examined using a noninvasive Doppler echocardiograph …

Chimeric Claudins Reveal Role In Neural Tube Defects, Wesley Allen, Nathan Beckett, Emma Brenchley, Jacob Wengler, Lauren Hall, Cailey Winn, Meredith Mann, Sion Jung, Spencer Thacker, Rachel May, Dario Mizrachi, Micheal Stark

Library/Life Sciences Undergraduate Poster Competition 2022

Claudins (CLDN), a family of proteins found in the tight junction, play a major role in membrane permeability. While claudin disruption is known to contribute to the formation of neural tube defects (NTD), current research methods rely heavily on a non-specific toxin, CPE, when exploring the importance of CLDNs within neural tube formation. This makes it difficult to identify individual CLDN’s contribution to NTD formation, creating a need for a more specific method.

Staying Hydrated: A Comparative Analysis Of Humectants In Human Skin, Ayden Olsen, Rachel Prince, Craig Reeves, Cassie Peterson, Jason Adams

Library/Life Sciences Undergraduate Poster Competition 2022

Humectants are an important class of compounds that attract and retain water within a cell. When mixed with water to create wetting solutions, humectants can prevent desiccation of cadaveric specimens. Recognizing a relative scarcity of comparative studies analyzing the effects of various wetting solutions on post preservation cadaveric maintenance, we utilized wet-dry analysis in order to compare the effects of four common humectants on water retention in human skin tissue. We created a concentration gradient for each humectant to identify the optimal concentrations of each compound for water retention, after which we compared water retention in tissue at the optimal …

New Treatment For Multiple Sclerosis Could Halt Disease Progression Without Weakening Immune System, Carter Helquist, Dario Mizrachi

Library/Life Sciences Undergraduate Poster Competition 2022

• Multiple Sclerosis (MS) is a debilitating neurological and autoimmune disease in which immune cells cause demyelination of axons in nervous tissue.
• Current treatments for the disease are principally aimed at weakening the immune system to therefore weaken the autoimmune attack on the brain. This leaves patients prone to other sicknesses.
• We seek a treatment that prevents the immune cells from entering the central nervous system (CNS) thereby protecting its cells.
• We can prevent immune cells from entering the CNS by strengthening the blood brain barrier through targeting claudin 5 proteins in the tight junctions.
• This new treatment could mean increased …

A Ketogenic Diet Enhances Hippocampal Mitochondrial Efficiency, Cali E. Warren, Erin R. Saito, Benjamin T. Bikman

Library/Life Sciences Undergraduate Poster Competition 2022

Mitochondrial dysfunction and cognitive impairment are common symptoms in many neurologic disorders, as well as in nonpathological aging. Ketones have been suggested as therapeutic for their relevance in epilepsy and other neurodegenerative diseases and psychiatric disorders such as Alzheimer’s and Parkinson’s disease, schizophrenia, and major depressive disorder.

An Interactive Game With Virtual Reality Immersion To Improve Cultural Sensitivity In Health Care, Paul J. Hershberger, Yong Pei, Timothy N. Crawford, Sabrina M. Neeley, Thomas Wischgoll, Dixit B. Patel, Miteshkumar M. Vasoya, Angie Castle, Sankalp Mishra, Lahari Surapaneni, Aman A. Pogaku, Aishwarya Bositty, Todd Pavlack

Health and Sport Science Faculty Publications

Purpose: Biased perceptions of individuals who are not part of one's in-groups tend to be negative and habitual. Because health care professionals are no less susceptible to biases than are others, the adverse impact of biases on marginalized populations in health care warrants continued attention and amelioration.Method: Two characters, a Syrian refugee with limited English proficiency and a black pregnant woman with a history of opioid use disorder, were developed for an online training simulation that includes an interactive life course experience focused on social determinants of health, and a clinical encounter in a community health center utilizing virtual reality …

Harnessing Blood Clot Removal Mechanisms After Germinal Matrix Hemorrhage, Jerry J. Flores

Loma Linda University Electronic Theses, Dissertations & Projects

Germinal matrix hemorrhage (GMH) is one of the leading causes of morbidity, mortality, and acquired infantile hydrocephalus in preterm infants in the United States, with little progress made in its clinical management. Blood clots have been shown to elicit secondary brain injury after GMH, by disrupting normal cerebrospinal fluid circulation and absorption after germinal matrix hemorrhage causing post-hemorrhagic hydrocephalus development. Current evidence suggests that rapid hematoma resolution is necessary to quickly improve neurological outcomes after hemorrhagic stroke. N-formyl peptide receptor 2 (FPR2), a G-protein-coupled receptor, has been shown to be neuroprotective after stroke. FPR2 activation has been associated with the …

Hsp90 Inhibitors Modulate Sars-Cov-2 Spike Protein Subunit 1-Induced Human Pulmonary Microvascular Endothelial Activation And Barrier Dysfunction, Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Betsy W. Gregory, Yara Khodour, John D. Catravas

Bioelectrics Publications

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused more than 5 million deaths worldwide. Multiple reports indicate that the endothelium is involved during SARS-Cov-2-related disease (COVID-19). Indeed, COVID-19 patients display increased thrombophilia with arterial and venous embolism and lung microcapillary thrombotic disease as major determinants of deaths. The pathophysiology of endothelial dysfunction in COVID-19 is not completely understood. We have investigated the role of subunit 1 of the SARS-CoV-2 spike protein (S1SP) in eliciting endothelial barrier dysfunction, characterized dose and time relationships, and tested the hypothesis that heat shock protein 90 (HSP90) inhibitors would prevent and repair such injury. S1SP …

Relating Metabolic Phenotypes To Movement Behavior In Brook Trout, Jacob E. Bowman

All NMU Master's Theses

Brook trout movement-related life history strategies vary considerably and range from individuals that stay within the same 100 meters their entire life to individuals that are potamodromous or anadromous. Potential drivers of movement life histories have been the subject of much research in fish, with genetic subpopulation explanations often failing to explain the phenomenon. Metabolic phenotypes have been suggested as a possible driver for expression of different movement life histories. I investigated if metabolic phenotypes are related to movement strategies within a population of brook trout (Salvelinus fontinalis) in Unnamed Creek, a tributary to the Rock River, Alger …

Parent Motivational Climate, Sport Enrollment Motives, And Young Athlete Commitment And Enjoyment In Year-Round Swimming, Rachel E. Williams, Christine M. Habeeb, Thomas D. Raedeke, Dee Dlugonski, Katrina D. Dubose

International Journal of Exercise Science

International Journal of Exercise Science 15(5): 358-372, 2022. Parents are known to influence the athlete sport experience through motivational climates. Athletes’ perception of motivational climates and their own motives for sport participation influence enjoyment and long-term sport commitment. It is unknown, however, the extent parent motives for initially enrolling their child in a year-round sports program associate with children’s sport participation enjoyment and commitment. The purposes of this study were to (a) determine parent motives for enrolling their child (5-8 years) in year-round swimming and (b) explore the relationships of parent motives and motivational climates with child enjoyment and commitment. …

Validation Of A New Ramping Aerobic Exercise Protocol (Ndks) In Overweight, Obese, And Normal Weight Individuals, Jill K. Nustad, Mckaela E. Halvorson, Alexa L. Scott

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 386-398, 2022. The research purpose was to establish reliability and validity of determining VO_2max via a new NDKS (Nustad Dressler Kobes Saghiv; named for the sir names of department faculty at the time) ramping protocol compared to the Standard Bruce protocol in normal weight, overweight, and obese individuals. Forty-two physically active participants (23M, 19F) ages 18-28 years were grouped into normal weight (N = 15, 8F, BMI 18.5-24.9 kg/m²), overweight (N = 27, 11F, BMI = 25-29.9 kg/m²), and Class I obese (N = 7, 1F, …

Effect Of Different Training Programs At Self-Selected Intensity On Body Composition, Perceptual Responses And Fitness Outcomes In Obese Women, Ragami Chaves Alves, Alysson Enes, Lucio Follador, Jonato Prestes, Sérgio Gregório Da Silva

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 373-385, 2022. Obesity induces several disorders, such as android obesity, insulin resistance, and coronary/peripheral artery disease, and obese individuals commonly have low adherence to training programs. Exercise at self-selected intensity is a feasible strategy to avoid dropouts of training routines. We aimed to assess the effects of different training programs at self-selected intensity on body composition, ratings of perceived exertion (RPE), feelings of pleasure and displeasure (FPD) and fitness outcomes (maximum oxygen uptake (VO2max) and maximum dynamic strength (1RM)) in obese women. Forty obese women (n = 40; Body Mass Index: 33.2 ± …

Acute Effects Of Velocity-Based Resistance Training On The Physical Functional Performance Of Older Adults, Suzy S. Pinto, Ewertton S. Bezerra, Keuly G. Silva, Rodrigo Ramirez-Campillo, Abderaouf B. Abderrahman

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 399-413, 2022. The aim of this study was to analyse the acute effects of velocity-based resistance training on the physical and functional performance of older adults. Twenty participants (70.4 ± 7.4 years) performed the deadlift exercise, in two different resistance training protocols. The moderate-velocity protocol (MV) predicted maximum loads so that the movement velocity during the concentric phase remained in the range of 0.5 to 0.7 m/s and the high-velocity protocol (HV) predicted maximum loads so that the movement velocity remained between 0.8 and 1.0 m/s. The jump height (cm), handgrip strength (kg), and …

Using Personality And Temperament To Predict Exercise Behavior: A Pilot Study Of The Braverman Nature Assessment, Ben M. Rosicky, Eric E. Hall

International Journal of Exercise Science

International Journal of Exercise Science 15(5): 341-357, 2022. The Braverman Nature Assessment (BNA) is intended to determine the dominant monoamine neurochemical that drives an individual’s temperament and behavior. The measure has been colloquially praised for the ability to determine the most effective exercise protocols for an individual based on their “dominant nature.” This study seeks to examine the proposed relationship between the Braverman Natures and exercise behavior. Seventy-three adults (57 females) between ages 18-65 (mean = 26 years) completed an online survey consisting of the BNA, Big Five Personality Inventory (BFI), and Aerobics Center Longitudinal Study Physical Activity Questionnaire (ACLSPAQ). …

Chronic Effects Of Heavy Load Activity Performed Before Resistance Training Sessions On The Physical Performance Of Youth Soccer Players, Guilherme Borsetti Businari, Julio Benvenutti Bueno De Camargo, Paulo Henrique Barbosa, Felipe Alves Brigatto, Marcelo Saldanha Aoki, Tiago Volpi Braz, Charles Ricardo Lopes

International Journal of Exercise Science

International Journal of Exercise Science 14(6): 1421-1434, 2021. The adoption of resistance training (RT) programs has been shown to positively influence sports performance-related parameters. However, the chronic effects of maximal strength protocols on the performance of soccer players are not completely investigated. The aim of this study was to evaluate the effects of performing two repetition maximum (2RM) before a resistance training session on the physical performance of youth soccer players. Seventeen players (under-20 category) were allocated in one of the following groups: 2RM + resistance training group (2RM + RT, n = 8) and resistance training group (RTG, n …

Comparison Of The Local Temperature, Lactate And Glucose After Three Different Strength Training Methods, Felipe J. Aidar, Dihogo Gama De Matos, Raphael Fabricio De Souza, Marcelo Danillo Matos Dos Santos, Anderson Carlos Marçal, Eduardo Borba Neves, Breno Guilherme De Araujo Tinoco Cabral, Victor Machado Reis

International Journal of Exercise Science

International Journal of Exercise Science 14(4): 1408-1420, 2021. This study aimed to evaluate the local temperature, lactate, and blood glucose in three strength training methods. The study included 12 male subjects; (22.15 ± 5.77 years, 76.85 ± 9.15 kg, 1.72 ± 0.09 m), with minimum of 12 months of strength training experience, and all participated in the three training methods: the occlusion training (Kaatsu); the tension training (Tension); and the traditional training (Traditional). The Kaatsu training consisted in 3 sets of 10RM with occlusion device in both arms inflated to a 130% occlusion pressure. In addition, the tension method was …

Effects Of A Demand-Valve Scuba Regulator On Cardiorespiratory Response During Submaximal Exercise Under Normobaric Conditions: A Preliminary Investigation, Christopher R. Kovacs Ph.D., Camille Dhom B.S.

International Journal of Aquatic Research and Education

SCUBA diving fatalities are often related to cardiac events triggered by stress linked to equipment. The purpose of this investigation was to examine the effects of a SCUBA regulator on cardiorespiratory exercise at a submaximal workload. Ten participants (mean = 21.5 yrs; s.d. = 1.16) completed two submaximal exercise tests at 1 ATA; one while breathing normally and a second while breathing directly from a demand valve SCUBA regulator. Total time to test completion (TOT), heart rate (HR), blood pressure (BP), rating of perceived exertion (RPE), and arterial oxygen levels were all assessed. No significant differences between conditions were found …

Effect Of Water Depth On Heart Rate And Core Temperature During Underwater Treadmill Walking, Carrie E. Bajenski, Brianna R. Brandon, Cailey A. Curry, Leslie Fajardo, Ryan T. Conners

International Journal of Aquatic Research and Education

Exercising using an underwater treadmill (UTM) has become a popular modality; however, few studies have focused on the physiological demands of UTM walking at varying water depths. Thus, the objective of this study was to investigate changes in heart rate (HR) and core temperature (CT) values in college-aged males and females while exercising at different water immersion depths using an UTM. Twenty participants (age = 21.50 ± 2.19 years; height = 169.04 ± 10.85cm; weight = 75.56 ± 22.28kg) walked at water depths of 10cm below the xiphoid process and at the level of the superior iliac crest (I.C.). Each …

Social Distancing, Psychological Mood And Physical Activity Behavior During Covid-19 In The United States, Grant A. Chesbro, Jessica A. Peterson, Christopher D. Black, Daniel Larson, Rebecca Larson

International Journal of Exercise Science

International Journal of Exercise Science 15(5): 313-329, 2022. Social distancing, during previous epidemics, has been shown to lead to poor mental health outcomes and reduced physical activity. The purpose of the present study was to examine the relationships between self-reported psychological state and physical activity behaviors of individuals under social distancing policies during the COVID-19 pandemic. 199 individuals (29.85 ± 10.22 yrs) in the United States who had been in social distancing for 2-4 weeks participated in this study. Participants answered a questionnaire regarding feelings of loneliness, depression, anxiety, mood state, and physical activity. 66.8% of participants had depressive symptoms …

Higher Body Mass Index Values Do Not Impact Physical Function And Lower-Extremity Muscle Strength Performance In Active Older Individuals, Vitor A.A.A. Siqueira, Emerson Sebastião, Clayton L. Camic, Dalmo R.L. Machado

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 330-340, 2022. This study examined the potential impact of BMI on physical function and lower-extremity muscle strength (leg extension and flexion peak torque) performance in active/trained older individuals. Sixty-four active/trained older individuals were enrolled, and later allocated to groups according to BMI categories (normal [≤ 24.9 kg/m²], overweight [25 to 29.9 kg/m²] and obese [≥ 30 kg/m²]). Sixty-four active/trained older individuals were enrolled, and later allocated to groups according to BMI categories (normal [≤ 24.9 kg/m²], overweight [25 to 29.9 kg/m²] and obese [≥ …

Us Army Reserve Officers’ Training Corps Cadets’ Knowledge Of Exercise-Related Musculoskeletal Injuries, Joshua D. Wooldridge, Noelle M. Selkow, Todd A. Mcloda, Kara N. Radzak

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 300-312, 2022. Musculoskeletal injuries, especially resulting from physical training, are a significant threat to military readiness. Due to costs related to treating injuries and the high probability of chronic, recurrent injuries, prevention should be a primary focus to maximize human performance and military success. However, in the US Army, many personnel are uninformed on injury prevention topics, and no research has identified injury prevention knowledge gaps in military leaders. This study examined the current knowledge of US Army ROTC cadets on injury prevention topics. This cross-sectional study was conducted at two university ROTC programs …

Glycogen Kinetics Of Wistar Rats: Different Exercise Intensities And Tissue Analyzed Influence, Carlos Dellavechia De Carvalho, Carlos Augusto Kalva-Filho, Alisson Luiz Da Rocha, Adelino Sanchez Ramos Da Silva, Marcelo Papoti

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 289-299, 2022. The aim of this study is to verify the influence of the intensity on muscle and hepatic glycogen depletion and recovery kinetics of Wistar rats, submitted to three acute training sessions with equalized loads. 81 male Wistar rats performed an incremental test to determine maximal running speed (MRS) and divided into 4 groups: baseline group (Control; n = 9); low intensity training session (G_Z1; n = 24; 48 minutes at 50% of MRS); moderate intensity group (G_Z2; n = 24; 32 minutes at 75% of MRS) and high …

An Analysis Of The Body Drag Test In Law Enforcement Recruits With Consideration To Current Population Demographics, Robert G. Lockie, Matthew R. Moreno, J. Jay Dawes, Robin Marc Orr, Karly A. Rodas, Joseph M. Dulla

International Journal of Exercise Science

International Journal of Exercise Science 15(7): 276-288, 2022. An essential job task for law enforcement officers is a body drag, where they must drag a person from a hazardous environment. In California, a 9.75-m body drag with a 74.84-kg dummy must be completed within 28 s to graduate academy. This mass is less than the average US adult, which may suggest it should be increased. This has not happened due to concerns regarding a potential increase in recruit injuries and failure rates. However, if recruits can complete the drag without formal training, this could leave scope for increasing the mass. …

A Comparison Of Three Different Warm-Ups On 800-Meter Running Performance In Elite Division I Track Athletes – A Pilot Study, Roger Keesling, Andreas N. Kavazis, Benjamin Wax, Matthew W. Miller, Brad Vickers

International Journal of Exercise Science

International Journal of Exercise Science 14(6): 1400-1407, 2021. Track and Field athletes perform different types of warm-ups at varying levels of volume and/or intensity prior to competition. Theoretically, this prepares sport specific muscles for activity by increasing muscle temperature, thus mitigating the chance for injury. There is a paucity of information regarding the optimum level for warm-ups regarding maximizing performance in middle distance events. The aim of this study was to examine the effects of three different warm-ups on 800-meter performance. Thirteen Division I student-athletes (seven males and six females) from the Southeastern Conference (SEC) who were middle distance runners …

Apoe Genetics Influence Murine Gut Microbiome, Diana J. Zajac, Stefan J. Green, Lance A. Johnson, Steven Estus

Physiology Faculty Publications

Apolipoprotein E (APOE) alleles impact pathogenesis and risk for multiple human diseases, making them primary targets for disease treatment and prevention. Previously, we and others reported an association between APOE alleles and the gut microbiome. Here, we evaluated effects of APOE heterozygosity and tested whether these overall results extended to mice maintained under ideal conditions for microbiome analyses. To model human APOE alleles, this study used APOE targeted replacement (TR) mice on a C57Bl/6 background. To minimize genetic drift, homozygous APOE3 mice were crossed to homozygous APOE2 or homozygous APOE4 mice prior to the study, and the resulting …

Sex Differences In Endurance Exercise Capacity And Skeletal Muscle Lipid Metabolism In Mice, Lola Holcomb, Patrick Rowe, Caitlin O'Neill, Elizabeth Dewitt, Stephen C. Kolwicz Jr.

Health and Exercise Physiology Faculty Publications

Previous studies suggest that sex differences in lipid metabolism exist with females demonstrating a higher utilization of lipids during exercise, which is mediated partly by increased utilization of muscle triglycerides. However, whether these changes in lipid metabolism contribute directly to endurance exercise performance is unclear. Therefore, the objective of this study was to investigate the contribution of exercise substrate metabolism to sex differences in endurance exercise capacity (EEC) in mice. Male and female C57BL/6-NCrl mice were subjected to an EEC test until exhaustion on a motorized treadmill. The treadmill was set at a 10% incline, and the speed gradually increased …

Keeping Your Cool: Thermoregulatory Performance And Plasticity In Desert Cricetid Rodents, Richard W. Ramirez, Eric A. Riddell, Steven R. Beissinger, Blair W. Wolf

Biology ETDs

Small mammals in hot deserts often avoid heat via nocturnality and fossoriality and are thought to have a limited capacity to dissipate heat using evaporative cooling. Research to date has focused on thermoregulatory responses to air temperatures (T_a) below body temperature (T_b). Consequently, the thermoregulatory performance of small mammals exposed to high air temperatures is poorly understood, particularly responses across geographic and seasonal scales. We quantified the seasonal thermoregulatory performance of four cricetid rodents (Neotoma albigula, N. lepida, Peromyscus eremicus, P. crinitus) exposed to high T_a, at four sites …