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Black Hole Spectroscopy And Tests Of General Relativity With Gw250114, A. G. Abac, I. Abouelfettouh, Teviet Creighton, Mario C. Diaz, Raul Alberto Espinosa Perez, J. Lawrence, Francisco Llamas Villarreal, Soma Mukherjee, Volker Quetschke, Miriam Ramos Arevalo, Wenhui Wang

Physics & Astronomy Faculty Publications

The binary black hole signal GW250114, the loudest gravitational wave detected to date, offers a unique opportunity to test Einstein’s general relativity (GR) in the high-velocity, strong-gravity regime and probe whether the remnant conforms to the Kerr metric. Upon perturbation, black holes emit a spectrum of damped sinusoids with specific, complex frequencies. Our analysis of the postmerger signal shows that at least two quasinormal modes are required to explain the data, with the most damped remaining statistically significant for about one cycle. We probe the remnant’s Kerr nature by constraining the spectroscopic pattern of the dominant quadrupolar (ℓ =𝑚 =2) …

Dhodh Links Mitochondrial Bioenergetics, One-Carbon Metabolism, And Dna Repair To Sustain Aggressive Prostate Adenocarcinoma, Venugopalareddy Mekala, Jun Hyoung Park, Uttam Rasaily, Vani Venkatappa, Karthik Reddy Kami Reddy, Vasanta Putluri, Kaveri Goel, Sandra L Grimm, Sai Manohar Thota, Taylor Morrison, Cristian Coarfa, Benny Abraham Kaipparettu, Chao Cheng, Nagireddy Putluri, Jeffrey A Jones, Mukesh K Nyati, Michael Ittmann, Natalie R Gassman, Arun Sreekumar

Faculty, Staff and Students Publications

Background

Dihydroorotate dehydrogenase (DHODH) is a mitochondrial enzyme that connects de novo pyrimidine biosynthesis with the electron transport chain (ETC) function. However, its broader role in prostate cancer (PCa) signaling and response to therapy remains unclear.

Methods

We combined transcriptomic, metabolomic, epigenomic, and functional analyses with clinical outcome data to explore the effects of DHODH depletion in ancestry-annotated European American (EA) and African American (AA) prostate cancer cell line models.

Results

DHODH was markedly overexpressed in malignant prostate epithelial cells and was abundant in tumors. Its knockdown hindered cell proliferation by causing pyrimidine depletion, while unexpectedly increasing oxidative phosphorylation, ETC …

Changing Patterns Of Psychotropics Use Among Older Adults With Intellectual Disability Over A Decade, With A Focus On Designated Mental Health Conditions, Rohit Shankar

Peninsula Medical School

ABSTRACTBackground: Psychotropics (sometimes off-label), mental health diagnoses and behaviours of concern are common in olderadults with intellectual disability. Guidelines recommend non-pharmacological interventions and regular medication review.This study examined changes in psychotropics among older adults (≥40) with intellectual disability.Methods: Longitudinal data were obtained from the Intellectual Disability Supplement to the Irish Longitudinal Study onAgeing (IDS-TILDA) at two timepoints [Wave 1(2009/10); Wave 4(2019/20)]. Post hoc analysis, Chi-squared tests and univariatebinary logistic regression were conducted.Results: Overall, psychotropics decreased (59.2% to 56.5%). Significant decreases in antipsychotics (43.1%–40.1%) and sedatives/hypnotics (13.6%–8.1%) and significant increase in antidepressants (26.2%–31.8%) were found. Nearly half of antidepressant usersreported depression …

Modelling Land Use Land Cover Change In Banyumas Regency Using Remote Sensing Data For Tourism Policy Evaluation, Revi Hernina, Arif Wicaksono, Adi Wibowo, Astrid Damayanti

Jurnal Geografi Lingkungan Tropik (Journal of Geography of Tropical Environments)

Tourism is essentially a geographical phenomenon, encompassing the movement and flow of people and spatial distribution patterns relating to land use consumption. The impacts of tourism on LUCC must track and monitor regrading effected to environment and human side. For decades, Banyumas Regency has been known for its famous tourist destinations such Baturaden District and numerous waterfalls. However, the development of tourism infrastructures within its vicinity has sparked complaints from communities, particularly damaged roads and decreasing tourist visits. From environmental perspective, excessive tourism development might cause decreasing natural carrying capacity. Therefore, to provide deeper analysis regarding the current tourism development, …

Levitating (Para Perasuk), Dereck Daschke

Journal of Religion & Film

This is a film review of Levitating (Para Perasuk)  (2026), directed by Wregas Bhanuteja.

Frank & Louis, John C. Lyden

Journal of Religion & Film

This is a film review of Frank & Louis (2025), directed by Petra Biondina Volpe.

Analysis Of Active Ingredients In Medicinal Herbs With High-Performance Liquid Chromatography And Related Technologies: A Review, T.-H. Tsai, C.-Y. Hong, C.-F. Chen

Journal of Food and Drug Analysis

An increasing number of analytical techniques have been brought to bear on the herbal drugs used in traditional Chinese medicine. This in turn has led to improved quality control of medicinal herbs, ingredient stability and shelf-life tests, ensurement of the concentrations of herbal drug ingredients in biological fluids, and pharmacokinetic studies. In the past decades, gas chromatography has been the method of choice for the analysis of volatile compounds, while liquid chromatography is a highly successful separation technique for nonvolatile molecules. Recently, high-performance liquid chromatography coupled with various column and detection systems have become some of the most important techniques …

Wicker, Dereck Daschke

Journal of Religion & Film

This is a film review of Wicker (2026), directed by Alex Huston Fischer and Eleanor Wilson.

The Only Living Pickpocket In New York, John C. Lyden

Journal of Religion & Film

This is a film review of The Only Living Pickpocket in New York (2025), directed by Noah Segan.

A Strengths, Weaknesses, Opportunities, And Threats (Swot) Analysis Of Chatgpt In Academic Help-Seeking, Fan Yang

International Journal of Teaching and Learning in Higher Education

This study explores the use of ChatGPT as a help-seeking tool in educational contexts, examining both its potential benefits and costs through a SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis. The purpose is to provide a comprehensive understanding of the various internal and external factors that either promote or hinder the use of ChatGPT for academic help-seeking. The strengths of ChatGPT, such as its 24/7 availability to provide immediate responses, non-judgmental tone, and the ability to provide personalized help based on specific prompts, position itself as a valuable resource for help-seekers. However, the low quality of the responses generated by …

Knife: The Attempted Murder Of Salman Rushdie, Dereck Daschke

Journal of Religion & Film

This is a film review of Knife: The Attempted Murder of Salman Rushdie (2026), directed by Alex Gibney.

The Ai Doc: Or How I Became An Apocaloptimist, John C. Lyden

Journal of Religion & Film

This is a film review of The AI Doc: Or How I Became an Apocaloptimist (2026), directed by Daniel Roher and Charlie Tyrell.

Review Of Picturing Utopia: Bertha Shambaugh And The Amana Photographers, Philip E. Webber

Communal Societies

No abstract provided.

Review Of Voices From The Farm, Bruce Plenk

Communal Societies

No abstract provided.

Review Of Moravian Women’S Memoirs: Their Related Lives, 1750-1820, Marlyn Mcgary Klee

Communal Societies

No abstract provided.

Review Of Two Kingdoms, Two Loyalties: Mennonite Pacifism In Modern America, Wendy E. Chmielewski

Communal Societies

No abstract provided.

Review Of A Socialist Utopia In The New South: The Ruskin Colonies In Tennessee And Georgia, 1894-1901, Yvonne Belanger Johnson

Communal Societies

No abstract provided.

Just To Breathe: Personal Recollections Of Synanon Founder Chuck Dederich, Ellen Broslovsky

Communal Societies

No abstract provided.

Review Of People Of The Rainbow: A Nomadic Utopia, Allen Butcher

Communal Societies

No abstract provided.

Communal Bonds: Contact Between The Amana Society And Other Communal Groups, 1843-1932, Peter Hoehnle

Communal Societies

No abstract provided.

The Commune That Didn’T Come To Town: The Love Israel Family And A Small Town In Idaho, Charles P. Lewarne

Communal Societies

No abstract provided.

“I Am, Dear Sir, Your Grateful Disciple, Margaret Chappellsmith.”, Clark Kimberling

Communal Societies

No abstract provided.

Regional Differences In The Size And Composition Of Communal Membership: The Shakers, 1850-1870, Bradley B. Andrew, Metin M. Cosgel

Communal Societies

No abstract provided.

Analyzing Communal Life-Spans: A Dynamic Structural Approach, James A. Kitts

Communal Societies

No abstract provided.

Communal Groups: Social Laboratories Or Places Of Exile?, Peter Michael Forster, William James Metcalf

Communal Societies

No abstract provided.

From The Editor, Rod Janzen

Communal Societies

No abstract provided.

Contents

Communal Societies

No abstract provided.

Front Matter

Communal Societies

No abstract provided.

Seizing The "Organic" Moment: Cuba's Agricultural Crossroads And Certified Organic Export Potential, Wesley J. Hevia, Michael T. Olexa, Thomas T. Ankersen, William A. Messina Jr.

Florida Journal of International Law

Cuba has been referred to as "the world's first national experiment in sustainable agriculture." Given the critical shortages in chemical inputs to Cuba's agricultural sector following the loss of Soviet economic support and subsidization, this may well be a fitting description. Cuba's use of the term "organic" to describe some of its agricultural production can be misleading. Not all of Cuba's "organic" products would satisfy the organic certification requirements for most developed countries. That being said, Cuba is shipping certified organic fresh citrus and citrus juices into EU markets. With proper investments and implementation of the appropriate procedures and protocols, …

Exploring Cuba's New Role In The World Economy: Paths And Perils, Wentong Zheng

Florida Journal of International Law

With the normalization of relations with the United States and other countries, Cuba is ushering in a new era with unprecedented opportunities in a globalized world. Participating in the world economy, however, is a risky proposition. It requires policymakers to carefully weigh the pros and cons of each development path and choose the one that best suits Cuba. It also requires policymakers to be prepared for the perils, both economic and legal, that may arise from Cuba's participation in the world economy. This Article explores Cuba's new role in the world economy and the perils that accompany this new role. …