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The Freedman's Savings Bank And Financial Literacy Education, Alexis Ann Ballance Jan 2026

The Freedman's Savings Bank And Financial Literacy Education, Alexis Ann Ballance

Law Student Publications

In the United States, white, non-Hispanic individuals possess approximately seven times the wealth of Black individuals. One recent study found that for every 100 dollars in wealth held by a white household, a Black household holds about fifteen dollars. This disparity in wealth accumulation is referred to as the wealth gap, and it has historically stratified along racial lines. Although income inequality contributes to this disparity, the racial wealth gap is much more pronounced and continues to grow. ...


Richmond Electronic Monitoring: The City Sees You While You're Sleeping, Fakira D. Johnson Jan 2026

Richmond Electronic Monitoring: The City Sees You While You're Sleeping, Fakira D. Johnson

Law Student Publications

The United States has increasingly recognized its reputation as a prison state, with widespread acknowledgment of its high incarceration rates. As of 2021, the United States imprisoned one out of every five prisoners in the world. Additionally, of its own population, the United States imprisoned one out of every one hundred people.

In response to this notoriety, worsening prison overcrowding, and the heightened risks posed by the COVID-19 pandemic, all fifty states, the District of Columbia, and the federal government increased their utilization of alternative measures to traditional incarceration. As both an addition and an alternative to traditional incarceration, criminal …


Georgia Southern Baseball Media Guides, Zach S. Henderson Library Special Collections Jan 2026

Georgia Southern Baseball Media Guides, Zach S. Henderson Library Special Collections

Finding Aids

This collection consists of Georgia Southern media guides for baseball prepared for journalists by the Athletics Department’s Office of Media Relations, dating from 1973-2012. The guides include schedules, statistics, win/loss records and notable accomplishments from previous seasons, profiles of coaches and players, general information about the university, and other information useful to reporters covering the team’s current season.

Find this collection in the University Libraries' catalog.


Georgia Southern Basketball Media Guides, Zach S. Henderson Library, Special Collections Jan 2026

Georgia Southern Basketball Media Guides, Zach S. Henderson Library, Special Collections

Finding Aids

The collection consists of Georgia Southern media guides for men’s and women’s basketball prepared for journalists by the Athletics Department’s Office of Media Relations, dating from 1991–1992 and 2015–2020. The guides include schedules, statistics, win/loss records and notable accomplishments from previous seasons, profiles of coaches and players, general information about the university, and other information useful to reporters covering the team’s current season.

Find this collection in the University Libraries' catalog.


The Future Begins Today: A Case Study On Retirement And Hsa Decisions, Bonnie R. Albritton, Amy Foshee Holmes, Stephan A. Stewart Jan 2026

The Future Begins Today: A Case Study On Retirement And Hsa Decisions, Bonnie R. Albritton, Amy Foshee Holmes, Stephan A. Stewart

School of Business Faculty Research

This case study explores retirement and health plan decisions faced by many students who are newly hired as full-time employees. Students are drawn into the storyline of two former college classmates and friends as one accepts a full-time position after graduation and the other seeks a master's degree in accounting. The accounting student takes on the role of a consultant to research retirement and health plan options, calculate the impact on take-home pay, and estimate taxable income and related taxes. Learning objectives for the case include understanding how the tax consequences differ between retirement plans, explaining the attributes of a …


Developing Empathy In Business Students Through Humanities-Based Study Abroad: An Exploratory Empirical Study, Jorge Colazo, Makiko Fukuda, Katsuo Nishikawa Chávez Jan 2026

Developing Empathy In Business Students Through Humanities-Based Study Abroad: An Exploratory Empirical Study, Jorge Colazo, Makiko Fukuda, Katsuo Nishikawa Chávez

School of Business Faculty Research

No abstract provided.


Clifton Photo Service Photographic Negatives, Zach S. Henderson Library Special Collections Jan 2026

Clifton Photo Service Photographic Negatives, Zach S. Henderson Library Special Collections

Finding Aids

This collection consists of 106 photographic negatives created by the Clifton Photo Service of Statesboro, Georgia. The images primarily depict local school life at Statesboro High School, Georgia Teachers College and Southeast Bulloch. Subjects include campus buildings and classrooms as well as student life, athletics, school events and student portraiture.


Georgia Southern Athletics Media Guides, Zach S. Henderson Library Special Collections Jan 2026

Georgia Southern Athletics Media Guides, Zach S. Henderson Library Special Collections

Finding Aids

This collection consists of reference guides and brochures prepared by the Athletics Department’s Office of Media Relations and includes materials related to Golf, Soccer (Men’s and Women’s), Softball, Swimming, Tennis (Men’s and Women’s), Track and Field, and Volleyball. Materials span 1973, 1987-2010 and include athletic schedules, statistics, win/loss records and notable accomplishments from previous seasons, profiles of coaches and players, general information about the university, and other information useful to reporters covering the team’s current season.

Find this collection in the University Libraries' catalog.


Do Variations In State Consultation Programs Affect Construction Fatality Rates?, Wayne B. Gray Jan 2026

Do Variations In State Consultation Programs Affect Construction Fatality Rates?, Wayne B. Gray

Economics

Background: Along with its enforcement program, the Occupational Safety and Health Administration (OSHA) has a voluntary consultation program that responds to requests from firms to identify hazards at their workplaces. We studied the effects of this program on fatal work injuries in the construction industry. Methods: We first examined differences across states in their consultation programs using data from 2016 through 2022, during which time 47,418 consultation visits were conducted in construction. These included differences in frequency of consultation visits at construction firms, the average number of hazards identified per visit, and the scope of those visits. We then used …


International Cocoa Trading Arrangements Between Industrialised And Developing Countries 1951–1999: A Structural Gravity Analysis, John Brown, Xenia Matschke, Juan René Rojas Rodríguez Jan 2026

International Cocoa Trading Arrangements Between Industrialised And Developing Countries 1951–1999: A Structural Gravity Analysis, John Brown, Xenia Matschke, Juan René Rojas Rodríguez

Economics

Using a state-of-the-art structural gravity model, we investigate the impact of various (post-)colonial cocoa trading arrangements on the cocoa trade between developing cocoa producer countries and rich industrial cocoa consumer nations in the time period 1951–1999. We find that in particular the trading arrangements of the European (Economic) Community (EEC/EC), such as the Association, Yaoundé and Lomé Agreements, as well as the UNCTAD International Cocoa Agreement, had a measurable positive impact on cocoa trade flows, in contrast to the British Commonwealth partnership or the GATT Generalised System of Preferences. In particular, the Yaoundé Agreement not only increased the trade between …


A Pilot Study Assessing The Oral Microbiome In Women Of Menopausal Age: Do Oral Nitrate–Reducing Bacteria Play A Role?, Katie Muddiman, Amazon Doble, Abish Stephen, Raul Bescos Garcia, Charlotte Illsley, Tomas Nicholas, Sally Hanks, Lisa Du Toit, Zoe Brookes Jan 2026

A Pilot Study Assessing The Oral Microbiome In Women Of Menopausal Age: Do Oral Nitrate–Reducing Bacteria Play A Role?, Katie Muddiman, Amazon Doble, Abish Stephen, Raul Bescos Garcia, Charlotte Illsley, Tomas Nicholas, Sally Hanks, Lisa Du Toit, Zoe Brookes

Peninsula Dental School

Introduction The links between oral health and female ageing are poorly understood, but many changes occur in the oral cavity of menopausal women that affect quality of life, and few current oral health interventions consider gender as part of their approach. The aim of this pilot study was to test the hypothesis that the oral microbiome and microenvironment change during female ageing and are thus worthy of further consideration both experimentally and clinically. Methods This observational pilot study retrospectively assessed women aged 18 to 89 years (n = 60) attending a UK primary care dental school facility for blood pressure …


Seeing Anxiety: Ecological Video Ethnography And Simulation To Understand Anxiety And Decision-Making In Dental Care, Mona Nasser, Hannah Drayson, Sally Hanks, Nicholas Peres, Michael Punt Jan 2026

Seeing Anxiety: Ecological Video Ethnography And Simulation To Understand Anxiety And Decision-Making In Dental Care, Mona Nasser, Hannah Drayson, Sally Hanks, Nicholas Peres, Michael Punt

Peninsula Dental School

BACKGROUND: Dental anxiety is a widespread barrier to care, often contributing to appointment avoidance, treatment disruption, and emotional strain for both patients and clinicians. While extensively studied as a psychological trait, less attention has been paid to how anxiety manifests situationally and relationally, through non-verbal, affective, and spatial cues within clinical encounters. Moreover, in certain contexts, such affective signals can intersect with decision-making processes, shaping how patients interpret, engage with, or withdraw from clinical choices.

OBJECTIVE: To explore how anxiety manifests within the micro-choreography of dental encounters, develop a taxonomy of 'anxious tells', and assess the utility of ecological video …


Who Bears The Cost? A Module For Researching The Intersection Of Technology, The Individual, And Climate Change, Jonathan Auyer Jan 2026

Who Bears The Cost? A Module For Researching The Intersection Of Technology, The Individual, And Climate Change, Jonathan Auyer

Climate Change and the Individual, 2025-26

Who Bears the Cost? A Module for Researching the Intersection of Technology, the Individual, and Climate Change is a multi-day writing and research module designed for first-year composition courses. Using the ongoing controversy surrounding the Science, Technology & Advanced Manufacturing Park (STAMP) in Genesee County, New York as a central case study, students investigate the ethical, environmental, and social dimensions of artificial intelligence and climate change. The module guides students from initial inquiry, exploring the philosophical question of whether technology is value-neutral or value-laden, through source research, collaborative discussion, and persuasive writing. Drawing on the rhetorical framework of They Say …


Rebuilding The Ship Of Theseus: Navigating Faculty-Librarian Relationships Through Changing Waters, Alan Witt Jan 2026

Rebuilding The Ship Of Theseus: Navigating Faculty-Librarian Relationships Through Changing Waters, Alan Witt

Milne Library

The Ship of Theseus is a philosophical paradox that poses a question of identity: If you repair every plank of a ship, replacing each with new wood, at what point does the ship cease to be the same ship? This is a useful metaphor for academic liaison librarians to consider when thinking about outreach to departments: your relationship to a department as a whole consists of the component connections, which change as individuals retire or leave. The goals of this chapter are to acknowledge the primacy of relationships in library outreach (and the consequences to the library of those relationships …


A Literature Review On Ethics In Medical Diagnostic Ai & Analysis Therein, Connor J. Turetzky Jan 2026

A Literature Review On Ethics In Medical Diagnostic Ai & Analysis Therein, Connor J. Turetzky

Master's Theses

Artificial Intelligence presents a very promising future in medicine. Being able to diagnose and recommend treatments quickly is vital in ensuring positive patient outcomes. However, the new technology is not without risk. In this narrative literature review, the risks of AI in terms of bias, ethics, and environmental impact will be explored through existing research. This paper will focus on research published between 2019 and 2026, highlighting the major ethical and systematic problems currently facing diagnostic AI. Historical bias in medical data has led to AI that share those biases, and humans inherit that bias creating a potential negative feedback …


Can An Experienced Qualitative Researcher Distinguish Ai From Human Qualitative Content Analysis?, Alexandra T. Lucas, Jianna Ramos, Maria Bajwa, Aaron Calhoun, Mark W. Scerbo, Janice C. Palaganas Jan 2026

Can An Experienced Qualitative Researcher Distinguish Ai From Human Qualitative Content Analysis?, Alexandra T. Lucas, Jianna Ramos, Maria Bajwa, Aaron Calhoun, Mark W. Scerbo, Janice C. Palaganas

Psychology Faculty Publications

Background

Artificial intelligence (AI) has become increasingly embedded in research workflows. Large language models (LLMs) are being used to code segments of text, organise codes into themes and interpret patterns within contexts. Recent comparisons between human and AI analyses demonstrate up to 80% thematic overlap, yet humans consistently exhibit deeper interpretive integration and contextual understanding. This study assesses whether experienced researchers can distinguish between entirely human-generated and AI-generated qualitative content analyses of a simulation debriefing.

Methods

We conducted a qualitative descriptive study comparing human-generated qualitative content analysis (QCA) with ChatGPT-4o-generated QCA using a single focus group transcript on emotion management …


What Race Means For Health Among Black Americans: How Microaggressions Shape Self-Efficacy And Readiness For Behavior Change, Amanda Lee Almond Jan 2026

What Race Means For Health Among Black Americans: How Microaggressions Shape Self-Efficacy And Readiness For Behavior Change, Amanda Lee Almond

Publications and Research

Objectives: Persistent racial disparities in cardiovascular health among Black Americans reflect not only structural inequities in the United States, but also the racialized meanings of cardiovascular disease reproduced through public and private health communication. Drawing on ecological systems theory, this research examines how beliefs linking race and cardiovascular disease are reinforced through routine clinical interactions and how these meanings shape health behavior change. Method: Across two experimental mixed-methods studies, a model integrating ecological, social–cognitive, and behavior change frameworks was tested. In Study 1 (N = 374), health-message framing was experimentally manipulated to examine effects on self-efficacy and decisional balance while …


Academic Department Indicators: 2025-2026, Systems Intelligence And Data Analytics, University Of Nebraska At Omaha Jan 2026

Academic Department Indicators: 2025-2026, Systems Intelligence And Data Analytics, University Of Nebraska At Omaha

Academic Department Indicators

The audience is the Academic Planning Council (APC), college and department heads, and faculty. The purpose is to report instructional productivity measures useful for making comparisons and observing trends. Selected departmental information in this report is submitted annually to the Delaware Study, a National Study of Instructional Costs and Productivity.

This Instructional Productivity information corresponds to the UNO state- and tuition-funded budget. The Supplemental Information at the end of the document provides counts and statistics for campus-wide programs embedded in most colleges. Only Dual Enrollment instruction is excluded from the productivity report since it is a fee-based instructional program for …


Workers’ Empowerment As U.S. Trade Policy, Desiree Leclercq Jan 2026

Workers’ Empowerment As U.S. Trade Policy, Desiree Leclercq

Scholarly Works

U.S. trade policy stands at an inflection point. The Biden administration’s “worker-centered” trade policy promised to empower foreign workers to improve employment and living standards globally, but it linked its trade assistance to political allies. The Trump administration’s “America First” trade policy promises to use tariffs and isolationism to protect and empower U.S. workers, but it is fostering antagonism rather than cooperation in trade. Both policies, while sharply diverging at the edges, recognize that U.S. trade policy affects employment opportunities in the United States. Both policies also critically overlook the relationship between the treatment of workers in trade partner countries, …


Stim1-Dependent Treg Dysfunction Promotes Cardiometabolic Hfpef: Insights From Patients And Animal Studies, Balaji Srinivas, Alluri Kiran, Hongmei Peng, Jiang Xu, Paula Fortuno, Jennifer May, Ismail El Moudden, Nour-Eddine Rhaleb, John M. Herre, Raymond L. Benza, Khalid Matrougui Jan 2026

Stim1-Dependent Treg Dysfunction Promotes Cardiometabolic Hfpef: Insights From Patients And Animal Studies, Balaji Srinivas, Alluri Kiran, Hongmei Peng, Jiang Xu, Paula Fortuno, Jennifer May, Ismail El Moudden, Nour-Eddine Rhaleb, John M. Herre, Raymond L. Benza, Khalid Matrougui

Department of Biomedical and Translational Sciences Faculty Publications

Background

Heart failure with preserved ejection fraction (HFpEF) arises from chronic cardiometabolic and vascular stress and is increasingly recognized as an inflammatory syndrome with immune dysregulation. Regulatory T cells (Tregs) are critical modulators of cardiovascular inflammation, yet the mechanisms driving Treg dysfunction in HFpEF remain poorly defined. stromal interaction molecule 1 (STIM1)-dependent calcium signaling is a key stress-responsive pathway in immune cells; however, its role in Treg maladaptation during HFpEF remains unknown.

Methods

Circulating Tregs from patients with and without HFpEF were analyzed for abundance, STIM1 expression, and stress-associated signaling pathways. To establish causality, mice with Treg-specific deletion of STIM1 …


Reconstituting A Constitution, And A Republic: The Architecture Of Authoritarian Rule, J. Maria Glover Jan 2026

Reconstituting A Constitution, And A Republic: The Architecture Of Authoritarian Rule, J. Maria Glover

Georgetown Law Faculty Publications and Other Works

A constitution can be remade without tearing it down, or even changing a single word. It is done by law.

“The judicial power is vested in one Supreme Court and in such inferior courts as Congress may establish,” whose “province and duty” it is to “say what the law is.” U.S. Const. Art. III §1; Marbury v. Madison, 5 U.S. 1 (Cranch) 137 (1803). It is not the power to remake the Constitution that grants it.

The Supreme Court is turning the inherited powers that hold power to law into instruments of its own aggrandizement. It is taking authority from …


Reflection In Still Waters: Generative Ai's Production Of Language, Jonathan D. Hawks Jan 2026

Reflection In Still Waters: Generative Ai's Production Of Language, Jonathan D. Hawks

Graduate Studies Theses and Dissertations 2026

Language is a conceptual process of meaning-making as well as a social construction as defined by Saussure, Bakhtin, and Lacan. Large Language Models (LLMs) engage with neither process and instead present language as a finished and consumable product which undermines its fundamental aspects. The difference between representing language through probability and its structural components instead of its more inherent qualities is not a pointless distinction. This paper utilizes Narcissus as a central metaphor to show how people misread the outputs of LLMs as language which imparts to those reflected words meaning on par with our own conceptualizations of reality. People …


Investigation Of Bulk And Periodically Stacked X(2) And X(3) Materials Using Mid-Infrared Femtosecond Pulses, Woraprach Kusolthossakul Jan 2026

Investigation Of Bulk And Periodically Stacked X(2) And X(3) Materials Using Mid-Infrared Femtosecond Pulses, Woraprach Kusolthossakul

Graduate Studies Theses and Dissertations 2026

Mid-infrared (MIR) spectral region represents a vital part of the electromagnetic spectrum, offering applications in spectroscopy, biomedicine, and remote sensing. However, there are no direct broadband MIR laser sources. Nonlinear frequency conversion techniques using second-order nonlinear materials, such as optical parametric oscillator (OPO) and intra-pulse difference frequency generator (IDFG), are promising methods for generating a broadband MIR spectrum. To achieve an efficient conversion, the phase matching condition between the interacting waves of the nonlinear process must be satisfied. Quasi-phase matching (QPM) is a special technique that enables efficient nonlinear processes in materials that cannot be conventionally phase matched using birefringence. …


Educational Case: Atypical Presentation Of Primary Hyperparathyroidism With Brown Tumor, Ariel Flotte, Jonathan Light, Harrison Klause, Richard M. Conran Jan 2026

Educational Case: Atypical Presentation Of Primary Hyperparathyroidism With Brown Tumor, Ariel Flotte, Jonathan Light, Harrison Klause, Richard M. Conran

Department of Biomedical and Translational Sciences Faculty Publications

The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology.


Yk-4-250 Mitigates Gastrointestinal Radiation Syndrome And Promotes Overall Survival Following Partial Body Radiation Injury, Vidya P. Kumar, Yali Kong, Kan Wang, Asa R. Britton-Jenkins, Stanton Dulan, Landon L. Moore, Debra Saunders, Randal May, Rheal Towner, Sanchita P. Ghosh, Courtney W. Houchen, Milton L. Brown Jan 2026

Yk-4-250 Mitigates Gastrointestinal Radiation Syndrome And Promotes Overall Survival Following Partial Body Radiation Injury, Vidya P. Kumar, Yali Kong, Kan Wang, Asa R. Britton-Jenkins, Stanton Dulan, Landon L. Moore, Debra Saunders, Randal May, Rheal Towner, Sanchita P. Ghosh, Courtney W. Houchen, Milton L. Brown

Department of Biomedical and Translational Sciences Faculty Publications

Acute gastrointestinal radiation syndrome (GI-ARS) is a significant health threat following high-dose ionizing radiation (IR) exposure, leading to severe morbidity and mortality. The syndrome is characterized by gastrointestinal tissue damage caused by angiotensin II (Ang II) and reactive oxygen species (ROS), resulting in impaired GI function, systemic bacteremia, multi-organ failure, and eventual death. Dysregulation of the renin-angiotensin system (RAS) via Ang II exacerbates ROS production through activation of the Angiotensin II type 1 receptor (AT1R). This underscores the need for agents capable of both scavenging ROS and inhibiting AT1R activity. To address this, we developed YK-4-250, a Tempol-conjugated angiotensin receptor …


Substitutive And Augmentative Delegation In Genai-Assisted Shopping: Perceived Benefits, Constraints, And Consumer Tension, Kexin Meng, Monsumi Singha Mahapatra, Jing Jian Xiao Jan 2026

Substitutive And Augmentative Delegation In Genai-Assisted Shopping: Perceived Benefits, Constraints, And Consumer Tension, Kexin Meng, Monsumi Singha Mahapatra, Jing Jian Xiao

Human Development and Family Science Faculty Publications

Generative artificial intelligence (GenAI) is reshaping consumer shopping by introducing new forms of decision support while also creating new tensions. Using the technology paradox perspective as a sensitizing theoretical lens alongside delegation theory, this study examines how perceived GenAI benefits (process efficiency, personalization, creative discovery, and immersive experience) and constraints (hallucination potential, privacy intrusiveness, algorithmic opacity, and information biases) are associated with performance ambiguity, emotional ambivalence, and autonomy threat through substitutive and augmentative delegation-related use patterns. Using survey data from 438 Chinese consumers, partial least squares structural equation modeling (PLS-SEM) showed that process efficiency was negatively associated with substitutive delegation …


Ritual Transformation, Deity Embodiment, And Nagualism In Formative Period Oaxaca, Mexico, Jeffrey S. Brzezinski, Guy David Hepp Jan 2026

Ritual Transformation, Deity Embodiment, And Nagualism In Formative Period Oaxaca, Mexico, Jeffrey S. Brzezinski, Guy David Hepp

Anthropology Faculty Publications

A hallmark of ancient Mesoamerican art and religion is the ability of ritual practitioners, sometimes called “shamans,” to transform. The Olmec were-jaguar is a well-known example of the phenomenon. Artifacts from different regions demonstrate that these beliefs involved many animal and spiritual entities and a porous boundary between humans and other beings. In this article, we examine the archaeology of ritual transformation in Preclassic or Formative period (2000 BC–AD 250) Oaxaca, Mexico. As links between the physical world and other dimensions, altered bodies reflect negotiated relationships among people, animals, ancestors, deities, and landforms. Traditional interpretations of transformational art have oversimplified …


The Career Choices Of Final Year Nursing Students In The United Kingdom: A Qualitative Study., Kevin Hambridge, Frazer Underwood, Gosia Bettache, Matt Carey, Halil Kaya, Lisa Burrows, Rachel Tims, Christian Brailsford Jan 2026

The Career Choices Of Final Year Nursing Students In The United Kingdom: A Qualitative Study., Kevin Hambridge, Frazer Underwood, Gosia Bettache, Matt Carey, Halil Kaya, Lisa Burrows, Rachel Tims, Christian Brailsford

School of Nursing and Midwifery

Aim: The aim of this study is to explore the career choices of final year under-graduate nursing students in the United Kingdom. Background: Worldwide there is a decreasing number of nurses and in the United Kingdom there is a decreasing amount of nursing students. There is sparce evidence relating to the career's choices of nursing students and reasons for those choices. Obtaining a deeper comprehension of these choices may aid healthcare employers, in partnership with universities, to design the future nursing workforce. Design: A qualitative design was used. Methods: Twenty-one final year under-graduate nursing students from across a range of …


35 Individuals With Huwe1-Related Neurodevelopmental Disorder And Suggested Clinical Evaluations, Mindy H. Li, Deziree L. Coleman, Kelsey Hogan, Danielle Luz, Lindsay Bhandari, Newell Belnap, Tiffany Busa, Charles Coutton, Klaus Dieterich, Svetlana Gorokhova, Clara Hildebrandt, Rachel Logan, Milena Mariani, Manuela Morleo, Vincenzo Nigro, John Pappas, Rachel Rabin, Kelly Schoch, Angelo Selicorni, Vandana Shashi, Rebecca Spillman, Jennifer Sullivan, Charlotte Tardy, Samantha A. Schrier Vergano, Brock Grill, Kristin Baranano Jan 2026

35 Individuals With Huwe1-Related Neurodevelopmental Disorder And Suggested Clinical Evaluations, Mindy H. Li, Deziree L. Coleman, Kelsey Hogan, Danielle Luz, Lindsay Bhandari, Newell Belnap, Tiffany Busa, Charles Coutton, Klaus Dieterich, Svetlana Gorokhova, Clara Hildebrandt, Rachel Logan, Milena Mariani, Manuela Morleo, Vincenzo Nigro, John Pappas, Rachel Rabin, Kelly Schoch, Angelo Selicorni, Vandana Shashi, Rebecca Spillman, Jennifer Sullivan, Charlotte Tardy, Samantha A. Schrier Vergano, Brock Grill, Kristin Baranano

Department of Pediatrics Faculty Publications

HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X-linked intellectual disability, including in the patients identified by Juberg, Marsidi, and Brooks. This report describes 35 additional cases of individuals with variants in HUWE1 and suggested guidelines for clinical management. Our study includes several female cases, which have not been widely reported previously. Our findings confirm earlier reported clinical features including developmental delay, autism, hypotonia, short stature, and dysmorphic facial features as well …


Assessing The Viability Of Speleothem Float Samples From Mammoth Cave National Park For Reconstruction Of The Laurentide Ice Sheet Position, Jackson Minton Jan 2026

Assessing The Viability Of Speleothem Float Samples From Mammoth Cave National Park For Reconstruction Of The Laurentide Ice Sheet Position, Jackson Minton

Honors Program Theses

Speleothems are widely used as paleoclimate archives, as they preserve geochemical records of environmental change through groundwater feeding. In regions like Mammoth Cave National Park, these records could be used to determine the position of the Laurentide Ice Sheet based on hydrologic changes. This study uses detached flowstone samples, known as float, from the New Discovery flowstone within Mammoth Cave to assess calcite preservation and the feasibility of accurate age dating to record paleoclimate information. Samples were analyzed using X-ray fluorescence to determine elemental composition and were prepared as petrographic thin sections for microscopic analysis. Petrographic observations revealed a range …