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Dapivirine Vaginal Ring For Prep: Findings And Lessons Learned From A Pilot Program In Mozambique, Hélder Macul, Aleny Couto, Eduardo De Gusmão, Thais Ferreira, Sérgio Chiale, Katia Ngale, Maria Gonçalves, Afonso Manuel, Danielle Resar, Wafaa El-Sadr

Dapivirine Vaginal Ring (PrEP Ring)

Background: Mozambique has high number of new HIV infections, with adolescent girls and young women (AGYW) disproportionally affected, representing 27% of the 91,644 annual infections. Oral PrEP has been implemented in Mozambique since 2017, however, while 13,585 AGYW initiated PrEP in Nampula Province since 2024, persistence remains a challenge, with 3,111(23%) remaining on PrEP by Dec 2024. To improve acceptance and persistence, the Ministry of Health, with ICAP support, introduced the Dapivirine Vaginal Ring (DVR) as a PrEP option in March 2025. Methods: DVR was offered at 25 de Setembro Health Centre, Nampula City, focusing on AGYW. It …

Subsidiarity Municipalism In Action: On Vincent V. Adams, Gregory E. Louis

University of Michigan Journal of Law Reform Caveat

Building on the author’s recent article Protecting Commoners’ Goods: Pluralist Coexistence Through the Common Good Constitution’s Subsidiarity Municipalism (PCG), this Essay deconstructs the recent New York appellate opinion in Vincent v. Adams. That case reverses a trial court opinion that PCG criticizes as an example of how current law misunderstands the proper relationship between local government and federal and state authorities. This Essay uses the appellate court decision in Vincent v. Adams to reinforce PCG’s thesis of subsidiarity municipalism, to offer another illustration of subsidiarity municipalism’s progressive potential, and to suggest how subsidiarity municipalism can inform the relationship between …

Vol7iss1 Cover, Hca Healthcare

HCA Healthcare Journal of Medicine Covers

Cover for Volume 7 Issue 1 of the HCA Healthcare Journal of Medicine.

Fisheries Management Paper No. 311: West Coast Deep Sea Crustacean Resource Harvest Strategy, Department Of Primary Industries And Regional Development, Western Australia

Fisheries Management Papers

Harvest strategies for Western Australia’s (WA) aquatic resources are formal documents developed by the Department of Primary Industries and Regional Development (DPIRD, the Department) to support decision-making processes that ensure the outcomes are consistent with the principles of Ecologically Sustainable Development (ESD; Fletcher 2002a) and Ecosystem Based Fisheries Management (EBFM; Fletcher et al. 2012). Harvest strategies are a key component of all contemporary fishery management systems and a requirement for certification under the Marine Stewardship Council (MSC). The objectives of ESD are reflected in the objectives of the Fish Resources Management Act 1994 (FRMA).

This West Coast Deep Sea Crustacean …

Vacancies Filled By Voters’ Voices: A Call For Open Special Elections With Ranked Choice Voting In New York, Fordham Law School Rule Of Law Clinic, Dani D'Annunzio, Dawn Edelman, David Zwick

Rule of Law Clinic

New York’s special election system for filling vacancies in the U.S. House of Representatives and the State Legislature excludes voters from the candidate selection process. Instead of voters selecting nominees, political party leaders designate their parties’ respective candidates. In this report, the Fordham Law School Rule of Law Clinic recommends reforming this system by implementing open special elections using ranked choice voting. All candidates who meet petition signature requirements, regardless of party affiliation, would compete in a single election. This reform would improve participation, representation, and accountability without sacrificing efficiency.

Variation In Antiviral Immunity And Inflammation Pathways Precedes Hiv-1 Infection In A High-Risk African Cohort, Mwikali Kioko, Shaban Mwangi, Lynn Fwambah, Amin Hassan, Jason Blackard, Philip Bejon, Eduard Sanders, Thumbi Ndung’U, Eunice Nduati, Abdirahman Abdi

Institute for Human Development, East Africa

BACKGROUND. Susceptibility to HIV-1 infection varies between individuals, but the biological determinants of acquisition risk remain poorly defined.

METHODS. We conducted a case-control study nested within a high-risk cohort in Kenya. We compared the plasma extracellular RNA collected before HIV-1 acquisition with that from matched uninfected individuals acting as controls to identify immunological processes linked to infection risk.

RESULTS. Individuals who later acquired HIV-1 exhibited upregulation of immune processes that facilitate viral infection, including T cell suppression and type II IFN and Th2 immune responses. In contrast, processes associated with antiviral defence and tissue repair, such as …

Return To Roots: Strunk, White, Orwell, Stewart Justman

Global Humanities and Religions Faculty Publications

Where did I get the idea that writing is a disciplined expression of free thought?

Flow State As A Counter Measure Against Cognitive Decline: What Counselors Should Know, Isaac Burt

Adultspan Journal

This perspective article explores the utilization of the neuroscience concept of flow state for therapeutic usage with older adult populations. Operationally defined, flow state is an altered state of consciousness (ASOC) that emerges when a person engages in an activity or endeavor. Once engrossed within this physical or cognitive undertaking, the person performs at their best (optimal) while expressing a feeling of joy and/or extreme satisfaction. To attain a flow state, there are several neurobiological mechanisms people must undergo. Due to beliefs that quality of life cannot increase in late adulthood, many older adults stop engaging in flow state activities. …

Older Adults And Suicide: Protective Pathways To Apply Shores In Counseling, Anna A. Ellenson, Jenny L. Cureton

Adultspan Journal

Older adult suicide (OAS) is a growing concern as the U.S. population continues to age and access to counseling expands. Despite legal and ethical requirements, counselors are often underprepared to address suicide in later life, especially through the lens of suicide protective factors (SPFs). This conceptual article introduces SHORES, a research-informed mnemonic (Skills and strategies for coping, Hope, Objections to suicide, Reasons for living/Restriction of means, Engaged care, and Support), to help counselors assess, intervene, and plan treatment with older adults. We review literature on OAS, highlight gaps in counselor training, and provide an application guide for using SHORES with …

Supporting Latine Older Adults’ Nutrition And Physical Health Goals In Counseling, Zachary Mcniece, Jacqueline Bergman

Adultspan Journal

Latine older adults face disproportionate risk of chronic nutrition-related conditions and food insecurity, which can exacerbate or contribute to mental health-related concerns. Cultural stigma toward mental illness can result in Latine clients, especially older adults, somatizing symptoms and focusing on physical health goals in counseling. Despite these intersecting needs, counselors often overlook their clients' physical health goals due to limited training and the assumption that medical providers alone should address these needs. This article advocates for the integration of basic, culturally responsive nutrition information into counseling practice to support client well-being while remaining within the scope of practice. We offer …

Gardening As A Psychosocial Well-Being Activity For Adults: Integrating Eco-Wellness And Developmental Theory, Christopher T. Belser, Helene Tavormina, Ann O'Hanlon

Adultspan Journal

Prior research has demonstrated the myriad of benefits that gardening can offer individuals, ranging from physical, mental, emotional, and social benefits. Though the counseling literature has begun to address the nature-wellness connection via EcoWellness theory (Reese & Myers, 2012), little attention has been paid to the benefits of gardening as a psychosocial well-being activity for adult populations. In this manuscript, authors offer a conceptual framework built on EcoWellness theory, psychosocial development theory, life-span, life-space career theory, and selection, optimization, and compensation theory that contextualizes gardening as a beneficial activity for young adults, middle adults, and older adults. Authors present specific …

Controlled Antibiotic Release From Emulsion-Loaded Alginate And Fibrin Hydrogels Using Ultrasound, Ziba Ghareh Nazi Fam, Asia Winslow, Mario Fabiilli, Sam Varghese, Brian Oeffinger, Flemming Forsberg, Noreen Hickok, Lauren Delaney

Department of Radiology Faculty Papers

Postoperative infections remain a major complication after spinal fusion surgery, often caused by biofilm-forming bacteria that resist short-term antibiotic prophylaxis. Vancomycin (VAN) is sometimes delivered locally during surgery; however, levels diminish rapidly, leaving patients vulnerable to late-onset infections. We developed a composite hydrogel integrating perfluorohexane-based emulsions within alginate or fibrin matrices to enable both sustained and ultrasound-triggered VAN release. Water-in-oil-in-water emulsions were prepared using fluorosurfactant-stabilized perfluorohexane as the volatile oil phase, then embedded in hydrogels and exposed to ultrasound (2.5 MHz, 5.5 MPa peak negative pressure) to initiate acoustic droplet vaporization for triggered release. Drug release was quantified spectrophotometrically and …

The Role Of Global Inflation In Estimation Of Us Output Components In The Post Bretton Woods Era: Evidence From Multivariate Unobserved Components Models, Arabinda Basistha

Economics Faculty Working Papers Series

We study the role of global inflation in estimation of US output components using multivariate unobserved components models. We augment the US inflation equations with global inflation based on strong empirical evidence in past studies. We further allow past global and domestic inflation to influence the output dynamics as a separate output component, beyond the output trend and output gap. The estimation results from the state-space model show a negative association of past inflation with this output component. The role of global inflation is informative in the negative association with the inflation based output component. The long-term fall in inflation …

Democracy And Public Policy Network Expert Analysis On "America At 250" February 2026 Poll, Robert Alexander

Democracy and Public Policy Network Polls

No abstract provided.

Mapping Social Determinants Of Health Data In Sub-Saharan Africa: A Scoping Review Protocol, Felix Anyiam, Jessica Gjonaj, Ngeresa Osango, Richard Mugo, Peace Aber, Jasmit Shah, Judith Mangeni, Rajesh Vedanthan, Joseph Hogan, Ann Mwangi

Internal Medicine, East Africa

Introduction Research has increasingly underscored the impact of factors such as socioeconomic status, education, healthcare access, housing and environmental conditions in shaping population health outcomes. These factors, collectively called social determinants of health (SDOH), provide crucial context for understanding drivers of health outcomes. In sub-Saharan Africa (SSA), the study of SDOH is critical due to the region’s unique sociocultural and economic conditions. Understanding how SDOH interacts with health systems and capturing SDOH in data is crucial for informing modelling efforts and policies improving population health more effectively. This scoping review aims to map the types of data used to capture …

2026 February - Tennessee Climate Snapshot, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Monthly Reports

No abstract provided.

Evaluation Of The Intempo Path Set For Cyberknife Prostate And Lung Sbrt: A Single-Institution Experience, Yingcui Jia, Lei Fu, Shari Rudoler, Eric Gressen, Yevgeniy Vinogradskiy, Qianyi Xu

Department of Radiation Oncology Faculty Papers

PURPOSE: The InTempo adaptive imaging system is an important component of the Accuray CyberKnife System, designed to enhance the system's ability to track and correct tumor motion during treatment. However, a limitation of this feature is the reduction of available nodes for treatment planning. The impact of a reduced number of nodes on the quality of InTempo-based treatment plans has not previously been evaluated. This retrospective study aims to compare the dosimetry of CyberKnife plans with and without The InTempo path set for both prostate and lung stereotactic body radiotherapy (SBRT).

METHODS: This study included twelve consecutive prostate SBRT patients …

High-Flow Oxygen Therapy In Ild Exacerbations: An Imperfect Therapy, Kathleen Spritzer, Jesse Roman, Ross Summer, Gautam George

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

No abstract provided.

Prediction Of Direct Normal Irradiance From Photovoltaic Power Plants Based On Clustering And Rime-Lightgbm, Can Zhou, Yuca I Zhou, Yanxiang Tan, Tian Xiao, Qiyue Xie, Zhongli Shen, Qiang Fu, Yuanheng Qin

Journal of Electric Power Science and Technology

The stability of the power output of the photovoltaic power plants is affected by the intermittency and uncertainty of direct normal irradiance (DNI). In order to solve this problem, a prediction model of DNI based on the clustering and rime optimization algorithm (RIME) optimizing the light gradient boosting machine (LightGBM) is proposed. Firstly, the strongly correlated meteorological parameters of the DNI are determined by the Pearson correlation coefficient, and the historical meteorological data is classified by the mini batch K-means (MBK) clustering algorithm. Then, RIME is used to optimize the hyperparameters of the LightGBM and to establish the prediction model …

Research On Mutual Support Capacity Analysis And Optimization Evaluation Of Mutual Support Capacity For Interconnected Regional Power Grids, Zhiqiang Liu, Geng Chen, Aihong Tang, Caifu Chen, Lulu Ma

Journal of Electric Power Science and Technology

In order to determine the mutual support capacity between regional power grids with complementary characteristics in terms of new energy output and electrical load demand, fully leverage the mutual support advantages of cross-regional interconnected grid capacity, reduce allocation of system reserve capacity, and enhance system operation reliability, the complementary characteristics between new energy output and electrical load demand in interconnected regional power grids and the feasibility of the mutual support between regional power grids are analyzed from the perspective of source-load matching. An algorithm for quantifying the mutual support capacity of the residual power after source-load matching is proposed. To …

Coordinated Reactive Voltage Control Of Distribution Network With Photovoltaic Inverter And Magnetically Controlled Reactor Based On Adaptive Voltage Partition Weights, Haiyun Wang, Qian Chen, Linyu Zhang, Xiyu Yin, Zhijian Zhang, Huayue Wei, Xiaoyue Chen

Journal of Electric Power Science and Technology

To utilize the reactive power regulation and voltage control capabilities of reactive power devices and photovoltaic inverters and improve system operation efficiency and safety stability, a coordinated reactive voltage control of the distribution network with photovoltaic inverter and magnetically controlled reactor based on adaptive voltage partition weights is proposed. By detecting the grid-connected point voltage range, the reactive power under the weight calculation integrated strategy is adaptively obtained, and the photovoltaic inverter is controlled. Meanwhile, an optimization model with voltage deviation and active transmission loss as objectives is established to optimize the reactive power of the distribution network containing magnetically …

Research On Distance Protection Under Critical Condition Based On Improved Ellipse Fitting, Mei Li, Zijian Zhang

Journal of Electric Power Science and Technology

When disturbances such as sudden load changes, generator tripping, or transmission line faults occur, the system will experience a power swing (PS). In this case, the impedance trajectory detected by the distance protection may encroach into zone Ⅲ of the protection, leading to maloperation or refusal operation of the distance protection and triggering cascade failures. Therefore, it is crucial to accurately distinguish PS and faults. A distance protection method based on improved ellipse fitting is proposed. Firstly, a Lissajous figure (LF) is constructed by using voltage and current signals at the protection mounting location, and a critical condition detection algorithm …

An Itpr1 Variant In The Ip3-Itpr1 Binding Pocket Associated With A Clinical Phenotype Of Athetoid Cerebral Palsy., Thania Ordaz, Jagadish Chandrabose Sundaramurthi, Adam S Arterbery, Anita M Bagley, Michael A Gargano, Jeremy P Bauer, Daniel Danis, Philip Giampietro, Ellen Raney, Lauren Rekerle, Mallory Shingle, Jon R Davids, Peter N Robinson

Faculty Research 2026

A de novo, missense variant in ITPR1-inositol 1,4,5-trisphosphate receptor type 1 (ITPR1), p.(Tyr567Cys), was identified by trio whole-genome sequencing in an individual diagnosed with Spinocerebellar ataxia 29 (SCA29) who was affected by cerebral palsy and global developmental delay. The variant affects a residue involved in Inositol 1,4,5-trisphosphate (IP3)-ITPR1 binding. Genotype-Phenotype correlation analysis of the set of missense variants affecting nine residues involved in IP3-ITPR1 binding in the current case and 170 reports of individuals with ITPR1 variants showed a significantly higher frequency of phenotypic features related to neurodevelopmental delay in these variants than in other ITPR1 variants. Our proband was …

The Synapse, February 2026, School Of Medicine Student Senate, New York Medical College

The Synapse

No abstract provided.

Baystate Health Nursing: Together In Excellence Newsletter - February 2026, Brenda Simpson Rn

Baystate Health Nursing: Together in Excellence Newsletters

Baystate Health Nursing: Together in Excellence Newsletter - February 2026

Himmelfarb Headlines - February/March 2026, The George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Headlines (2009 - present)

News, information, and resources relating to Himmelfarb Library that is of interest to patrons.

Covering The Care: Chronic Conditions, Including Behavioral Health, Drive A Significant Portion Of High-Utilizer Emergency Department Visits In 2023, Erica-Lyn Plante, Ms, Deborah Fournier, Jd

All Materials

This data brief summarizes a retrospective analysis of commercial, New Hampshire Medicaid, and New Hampshire Medicare claims, examining common reasons for emergency department visits among children aged 0-18, adults aged 19-44, adults aged 45-64, and adults aged 65 years and older in calendar year 2023.

Improvements In Eeg Tracing Following Initiation Of Cannabidiol: A Case Report, Katherine Horman, Ara Hall, Kailash Pawar

Posters

No abstract provided.

Hiding In Plain Sight: Trafficking Persons With Disabilities For Begging In Ethiopia, Annabel Erulkar, Galan Bekuma, Lemi Negeri, Getachew Teshome Eregata, Musie Tilahun, Getu Asnake, Getahun Semeon, Weyneshet Gezahegn

Humanitarian Task Force

Adults and children with disabilities are at increased risk of human trafficking for begging because of extreme poverty and high rates of illiteracy; cultural norms and stigma leading to low status; lack of social and legal protection; and their reliance on others for sustenance and help with movement, especially in cities which are fraught with risks. Despite this, trafficking of persons with disabilities for begging has received very little attention from researchers, human rights groups or disability advocates. This report presents findings from among the first studies to focus on trafficking of persons with disabilities for begging.

A ‘Digital Dominion’: Launching The Commonwealth Model Law On Digital Trade, Craig Atkinson

Centre for Digital Law

A legislative text published for the benefit of its 56 member countries, the Commonwealth of Nations officially adopted the Model Law on Digital Trade (MLDT) in September 2025. The Commonwealth MLDT addresses a persistent barrier to digital trade (i.e., all trade that is digitally ordered and/or digitally delivered): the laws of many jurisdictions do not sufficiently recognise the legal requirements of electronic commerce (e-commerce) and continue to emphasise paper-bases for commercial communications and transactions in domestic and cross-border contexts.