Digital Commons Network^™

Save The Date: Surrogate Court Judge Panel, Cardozo Trusts And Estates Law Society

2025–2026 Flyers

Welcoming  Hon. Rita Mella, Hon. Brandon Sall and Hon. Sara McGinty  on  a panel to discuss T&E in the courtroom!

Women In Sports: Game Changers, Cardozo Fame Center, Cardozo Sports Law Society (Csls)

2025–2026 Flyers

Join Cardozo's Sports Law Society for a special event on Monday, February 9th at 1:00 p.m. in Room 304. This panel will highlight the experiences, career paths, and impact of women working across the sports law industry. The discussion will explore professional development, leadership, and mentorship, as well as the legal and structural challenges women continue to navigate in sports-related legal fields. Panelists will address emerging opportunities for women in sports law, strategies for building sustainable careers in the industry, and the evolving role of women in shaping the future of sports governance, policy, and business. Panelists will also answer …

High-Throughput Multi-Organ Proteomics Workflow For Drug Efficacy And Toxicity Analysis, Yun Xiong, Lin Tan, Wai-Kin Chan, Dandan Zhu, Huimin Zhang, Sri Ramya Donepudi, Bo Wei, Bao Tran, Sara Martinez, Iqbal Mahmud, Faiza Hanif Waghu, Hamish I Stewart, Daniel J Hermanson, Rehan Akbani, John N Weinstein, Junjie Chen, Philip L Lorenzi

Faculty, Staff and Student Publications

Rapid and comprehensive analysis of complex proteomes across large sample sets is vital for unlocking the potential of systems biology. We present a high-throughput mass spectrometry (MS) proteomics method that integrates narrow-window data-independent acquisition (nDIA) with short-gradient micro-flow chromatography, enabling profiling of >240 samples per day. This optimized MS approach identifies 6,201 and 7,466 human proteins with 1- and 2-min gradients, respectively. As a practical application, we analyzed 507 samples composed of 13 different tissues from mice treated with the enzyme-drug L-asparaginase (ASNase) or its glutaminase-free Q59L mutant, generating a quantitative profile of 11,472 proteins following drug treatment. The MS …

Multimodal Spatial-Omics Reveal Co-Evolution Of Alveolar Progenitors And Proinflammatory Niches In Progression Of Lung Precursor Lesions, Fuduan Peng, Ansam Sinjab, Yibo Dai, Warapen Treekitkarnmongkol, Sujuan Yang, Tieling Zhou, Alejandra G Serrano, Avantika Krishna, Nastaran Karimi, Manvi Sharma, Akshay Basi, Guangsheng Pei, Jianlong Liao, Yunhe Liu, Jiping Feng, Zahraa Rahal, Yang Liu, Jiahui Jiang, Kai Yu, Tala Noun, Yuejiang Liu, Khaja Khan, Kyung Serk Cho, Jichao Chen, Luisa M Solis, Sarah Mazzilli, Steven Dubinett, Tina Cascone, Avrum E Spira, Stephen Swisher, Naoe Jimbo, Takuo Hayashi, Satsuki Kishikawa, Kazuya Takamochi, Tomoo Itoh, Takashi Yao, Kenji Suzuki, Neda Kalhor, Ignacio I Wistuba, Mingyao Li, Seyed Javad Moghaddam, Junya Fujimoto, Jared Burks, Jeffrey Myers, Kadir Akdemir, Linghua Wang, Humam Kadara

Faculty, Staff and Student Publications

The co-evolution of different cell subsets in the progression of precursor lesions to lung adenocarcinoma (LUAD) is incompletely understood. We generated spatial transcriptomic maps of 56 human precursor lesions and LUADs from 25 patients and of an independent cohort of 36 lesions from 19 patients, analyzing a total of 486,519 spots and 5.4 million cells. We identify region-specific programs that distinguish precursors from LUADs. Spatially resolved clonal architectures reveal patient-specific heterogeneity in evolution of precursors to LUADs. We find epithelial alveolar progenitors expressing tumor-associated meta-programs and residing in niches enriched with proinflammatory subsets including IL1B high macrophages. Epithelial-proinflammatory niches are …

Wdr4 Regulates Ribosome Biogenesis And Intestinal Homeostasis Via Let-7, Kreeti Kajal, Elham Rastegari, Wen-Der Wang, Jian-Chiuan Li, Chun-Hong Chen, Wei Chiao Chang, Kevin Tsai, Tsai Ming Lu, Kartik Venkatachalam, Hwei-Jan Hsu

Faculty, Staff and Student Publications

Proper regulation of ribosome biogenesis is essential for stem cell function and tissue homeostasis, yet its upstream control in adult intestinal stem cells (ISCs) remains unclear. Here, we identify the WD repeat protein Wdr4 as a key regulator of ISC homeostasis in the Drosophila midgut. Wdr4 cooperates with the methyltransferase Mettl1 to catalyze N⁷-methylguanosine (m⁷G) modification of let-7 miRNA. Wdr4 or Mettl1 depletion disrupts this modification, reducing let-7 levels and aberrantly activating TOR-JNK-dMyc signaling. This drives elevated ribosome biogenesis, ISC overproliferation, misdifferentiation, and intestinal dysplasia. Overexpression of let-7, inhibition of TOR, or suppression of JNK rescues these defects. Importantly, expression …

Ubiquitination-Directed Cytosolic Dna Degradation Governs Cgas-Sting-Mediated Immune Response To Dna Damage, Lei Li, Qi Ye, Jinlu Ma, Zixi Wang, Tianjie Liu, Mingming Lu, Haohan Xiang, Buyun Li, Shan Xu, Ke Wang, Yule Chen, Jiaqi Chen, Bohan Ma, Wenyue Huang, Mengjiao Cai, Nan Wu, Yanqiang Li, Jiale An, Chongming Jiang, Rui Ye, Jing Liu, Steven H Lin, Yang Gao, Jian Ma, Lei Li

Faculty, Staff and Student Publications

Activation of cGAS-STING signaling in cancer cells requires cytosolic DNA produced by intrinsic or treatment-induced DNA damage. However, clinical efforts to exploit this pathway to improve immunotherapy have yielded limited success, highlighting gaps in understanding the link between DNA damage and immunotherapy. Here, we identify ubiquitination-directed cytosolic DNA degradation as a critical determinant for cGAS-STING activation following DNA damage. Mechanistically, the cytosolic DNA exonuclease TREX1 is degraded by the E3 ubiquitin ligase SPOP but is reversely stabilized by the deubiquitinase USP7. Cancer-associated SPOP mutations or USP7 overexpression elevate TREX1 levels, promoting cytosolic DNA degradation and impairing cGAS-STING-mediated immune activation. Notably, …

Prevalence Of Her2-Low Status And Outcomes In Early-Stage Her2-Negative Breast Cancer, Akshara Singareeka Raghavendra, Diane D Liu, Sarah Pasyar, Senthil Damodaran, Yu Shen, Carlos H Barcenas

Faculty, Staff and Student Publications

HER2-low breast cancer (IHC 1+ or 2+ without HER2 gene amplification) is a distinct and understudied subtype. In a cohort of 14,593 early-stage breast cancer patients treated at MD Anderson from 2006 to 2019, 60.4% were HER2-low. Multivariable analysis showed HER2-low status was independently associated with race, histologic subtype, higher nuclear grade and stage, and estrogen receptor (ER) positivity. Among 2464 patients receiving neoadjuvant chemotherapy, HER2-low status was not linked to pathologic complete response (pCR), overall survival (OS), or disease-free survival (DFS) compared to HER2-0 tumors. Factors predicting pCR included nuclear grade III, stage I, invasive ductal carcinoma, lower ER/PR …

Familial History Of Aortic Disease Does Not Affect Outcomes Of Fenestrated-Branched Endovascular Aortic Repair In Patients With Complex Aortic Aneurysms, Thomas Mesnard, Steven Maximus, Ying Huang, Gustavo S Oderich

Faculty, Staff and Student Publications

Purpose: Familial history of aortic disease has been associated with increased risk of aneurysm-related complications after standard endovascular aortic repair. The aim of this study was to evaluate outcomes of fenestrated-branched endovascular aortic repair (FB-EVAR) for complex aortic aneurysms in patients with or without familial aortic aneurysms (FAAs).

Materials and methods: We reviewed the clinical data of consecutive patients enrolled in a prospective non-randomized study to investigate outcomes after FB-EVAR for treatment of complex aortic aneurysms between 2013 and 2022. Familial aortic aneurysm was defined as occurrence of an aortic aneurysm or dissections in a first- or second-degree relative and …

Multimodal Spatial-Omics Reveal Co-Evolution Of Alveolar Progenitors And Proinflammatory Niches In Progression Of Lung Precursor Lesions, Fuduan Peng, Ansam Sinjab, Yibo Dai, Warapen Treekitkarnmongkol, Sujuan Yang, Lorena I Gomez Bolanos, Tieling Zhou, Minyue Chen, Alejandra G Serrano, Avantika Krishna, Nastaran Karimi, Manvi Sharma, Akshay Basi, Guangsheng Pei, Jianlong Liao, Yunhe Liu, Jiping Feng, Zahraa Rahal, Yang Liu, Jiahui Jiang, Kai Yu, Tala Noun, Yuejiang Liu, Khaja Khan, Kyung Serk Cho, Jichao Chen, Luisa M Solis, Sarah Mazzilli, Steven Dubinett, Tina Cascone, Avrum E Spira, Stephen Swisher, Naoe Jimbo, Takuo Hayashi, Satsuki Kishikawa, Kazuya Takamochi, Tomoo Itoh, Takashi Yao, Kenji Suzuki, Neda Kalhor, Ignacio I Wistuba, Mingyao Li, Seyed Javad Moghaddam, Junya Fujimoto, Jared Burks, Jeffrey Myers, Kadir Akdemir, Linghua Wang, Humam Kadara

Faculty, Staff and Student Publications

The co-evolution of different cell subsets in the progression of precursor lesions to lung adenocarcinoma (LUAD) is incompletely understood. We generated spatial transcriptomic maps of 56 human precursor lesions and LUADs from 25 patients and of an independent cohort of 36 lesions from 19 patients, analyzing a total of 486,519 spots and 5.4 million cells. We identify region-specific programs that distinguish precursors from LUADs. Spatially resolved clonal architectures reveal patient-specific heterogeneity in evolution of precursors to LUADs. We find epithelial alveolar progenitors expressing tumor-associated meta-programs and residing in niches enriched with proinflammatory subsets including IL1B high macrophages. Epithelial-proinflammatory niches are …

Ex Vivo Microfluidic Model Identifies A Role For Shear Stress During Ovarian Tumor Cell Attachment To Peritoneal Mesothelial Cells, Vasilios A Morikis, Breanna Baker, Jillian A Martin, Angela Schab, Alessandra Dimauro, Gregory D Longmore, Whitney R Grither

2020-Current year OA Pubs

Ascites, or a pathologic accumulation of intra-abdominal fluid, is a key feature of intraperitoneally disseminating cancers, such as ovarian cancer. This pathological fluid buildup can influence the adhesive abilities of ovarian cancer cells, as they spread throughout the abdominal cavity to form metastatic implants on organs lined with a specialized monolayer of mesothelial cells. Robust methods for assessing the impact of fluid shear stress on this cell-cell interaction are lacking. Here, we develop and characterize a novel microfluidic device that allows for the determination of the attachment of ovarian tumor cells to mesothelial cells under the influence of fluid flow. …

Striation Characteristics In Atmospheric Pressure Ac-Driven Glow Discharge Operating In Monoatomic Gas, Ayuob K. Alwahaibi, Sang Hee Won, Tanvir Farouk

Faculty Publications

Striation in an atmospheric pressure AC-driven helium glow discharge operating at 25 kHz is experimentally characterized. Striation behavior is characterized by the visualization of discharges and voltage–current measurements over a range of plasma power. Voltage–current characteris tics reveal that striations form in the “normal” glow regime of operation, with a higher number of strata at low current, diminishing as dis charge current increases. The relative differences and similarities in the striation patterns during the positive and negative cycles are identified. High-speed imaging shows the striations to be traveling in time—“moving striations.” The spatial luminosity of the striations is tracked over …

Diurnal Rhythm In Chimeric Antigen Receptor T Cell Effectiveness In An Observational Study Of 715 Patients, Patrick G. Lyons, Emily Gill, Prisha Kumar, Melissa Beasley, Brenna Park-Egan, Zulfiqar A. Lokhandwala, Katie M. Lebold, Brandon Hayes-Lattin, Catherine L. Hough, Nathan Singh, Guy Hazan, Huram Mok, Janice M. Huss, Colleen A. Mcevoy, Jeffrey A. Haspel

2020-Current year OA Pubs

BACKGROUNDChimeric antigen receptor (CAR) T cells are a leading immunotherapy for refractory B cell malignancies; however, their effect is limited by toxicity and incomplete efficacy. Daily (circadian) rhythms in immune function may offer a lever to boost therapeutic success; however, their clinical relevance to CAR T cell therapy remains unknown.METHODSWe retrospectively analyzed CAR T cell survival and complications based on infusion time at 2 geographically distinct hospitals: Washington University School of Medicine in St. Louis, Missouri, USA (n = 384) and Oregon Health & Science University in Portland, Oregon, USA (n = 331) between January 2018 and March 2025. The …

Design And Economic Assessment Of A Sustainable Standalone Photovoltaic System For Hospital Lift Applications, Tasneem M. Abed, Saad S. Eskander, Mohamed A. Elsayes, Mohamed Zaki

Mansoura Engineering Journal

This study presents an optimized design and operation strategy for a stand-alone solar photovoltaic power system to drive a 4.5 kW elevator at Mansoura University Hospital, Egypt. The research aims to reduce the battery bank capacity and overall system cost while maximizing the utilization of solar panels. A novel "Optimum Operator System" is proposed, incorporating three power switches controlled by an Arduino microcontroller. The system's performance is analyzed through extensive modeling, simulation, and experimental validation. Results show a significant reduction in battery bank capacity, with 7 fewer 100 Ah batteries required compared to conventional systems. The proposed method significantly enhances …

Staff Education Project On Enhancing Provider Knowledge And Confidence In Adolescent Depression Assessment Using The Phq-9 Tool, Beatrice Ogoh Stephens

Walden Dissertations and Doctoral Studies

Adolescent depression is a developing public health issue, especially in underprivileged areas where delayed diagnosis and treatment are caused by uneven screening procedures and inadequate provider training. By increasing provider and staff knowledge, confidence, and use of the Patient Health Questionnaire-9 (PHQ-9) for systematic teen depression screening, this staff education project filled a practice gap in a primary care clinic. Fifteen clinic staff members who provide adolescent care participated in a four-hour evidence-based educational intervention that was guided by the ADDIE instructional design approach. Fifteen clinic staff members who provide adolescent care participated in a four-hour evidence-based educational intervention that …

Computational Investigation Of Cavitation Inception In Centrifugal Pumps, Mohamed Ibrahim Eldesouky, Asmaa Khater, Abdel-Rahim Dohina, Mohamed Rabie

Mansoura Engineering Journal

This study examines the effects of suction chamber baffle configurations on both hydraulic efficiency and cavitation characteristics in a low specific speed centrifugal pump. Four baffle configurations (zero, one, two, and three baffles) were tested at three different heights using refined computational fluid dynamics simulations. The Zwart-Gerber-Belamri cavitation model was enhanced by adjusting nucleation site radius and evaporation coefficient values to better align with previous research findings. Results revealed that the optimal baffle height is approximately one-third of the impeller suction eye radius, significantly improving cavitation resistance. Under non-cavitation conditions, all baffled configurations outperformed the no-baffle setup, with a single …

Enhancing Foam Concrete Performance: The Role Of Magnetized Water On Workability, Strength, And Microstructure Properties, Amr Elkazzaz, Mohamed M. Yousry Elshikh, Walid E. Elemam

Mansoura Engineering Journal

Conventional foam concrete suffers from low strength and heterogeneous pore structure due to its porous structure and incomplete hydration, limiting its structural applications. This study investigates the use of magnetized water (MW) as a mixing medium to enhance hydration efficiency and improve both fresh and hardened properties of foam concrete. Three density grades 620, 1300, and 1900 kg/m³, designated as Groups A, B, and C were prepared and tested. Compressive strength measurements indicated that MW enhanced performance across all densities. In Group A, 28-day strength increased slightly from 2.4 MPa with tap water (TW) to 2.8 MPa with MW. For …

Life-Cycle-Oriented Selection Framework For Solar Shading Devices In Hot–Arid Building Façades: From Traditional Precedents To Pv-Integrated Systems, Sameh Ahmed Qadry

Mansoura Engineering Journal

Abstract

This study proposes a life-cycle–oriented, computationally light framework for selecting solar shading devices in hot–arid building façades. While previous research has extensively analysed shading performance using detailed simulations, most studies focus on single systems or materials, rarely comparing traditional, modern, and PVintegrated solutions within a unified life-cycle and operation–maintenance perspective. The research addresses this gap by integrating three shading families—traditional local precedents (e.g. mashrabiya, rawshan), modern fixed and dynamic systems, and hybrid PV-integrated façades—into a comparative decision-support framework tailored to hot–arid climates. Methodologically, the study combines: (1) a structured descriptive–analytical literature review with analytical coding of key attributes (design …

On Nunation (Tanwin) In Arabic Grammar: Notes And Questions, Fatima Yahyaoui

Faits de Langue et Société (FLS)

The (tanwiin تنوين) in Arabic is a suffix added to the noun, after the case vowel. In this article, we will attempt to make some observations on the definition of the content and nature of tanwiin in the Arabic language and its classifications as mentioned by Arabic grammarians. We will also ask some questions about its linguistic status and its complementary distribution with the determinant (al ال) in the common name in Arabic.

The Lexical Richness Of Abdelkebir Khatibi’S Fictional Works, Abdellah Kaaouas

Faits de Langue et Société (FLS)

This article presents a stylo-statistical analysis of lexical richness across the seven novels of Abdelkébir Khatibi. The objective is to establish an objective classification of these works by quantifying the ratio between word occurrences (N) and distinct vocabulary terms (V). The methodology is based on a comparative approach utilizing several mathematical models: Guiraud’s formula, Muller’s binomial law, and, most notably, Brunet’s [W] index, selected for its ability to neutralize the influence of text length. The results demonstrate that vocabulary density in Khatibi’s work is not chronological but rather tied to specific stylistic choices, establishing La Mémoire tatouée as the most …

Symbolism In Tahar Ben Jelloun’S Novels, Ouidiane El Aref

Faits de Langue et Société (FLS)

This article examines the role of symbolism in the novelistic universe of Tahar Ben Jelloun, a major figure of French-language Maghrebi literature. After outlining the genre’s key features (cultural hybridity, identity issues, and voices of the marginalized), the study offers a thematic reading of recurrent symbols. It focuses on pairs such as earth/sea and red/blue, as well as the numbers seven/five, analyzing their occurrences, contexts, and connotative values (origins, exile, memory, violence, desire, and the sacred). The paper shows how these signs structure Ben Jelloun’s poetics and invite critical interpretation of social realities.

Deconstructing Gender Relations In Selected Essays By Abdelkébir Khatibi And Fatema Mernissi, Hanane El Majidi

Faits de Langue et Société (FLS)

This article examines how gender relations are deconstructed in selected essays by Abdelkébir Khatibi and Fatema Mernissi, situating their work within Moroccan debates of the 1980s and 1990s on social change and the family. It analyzes writing strategies and theoretical resources—literary and sociological—used to question gender as a socially acquired performance. Particular attention is given to Mernissi’s texts, where multiple female voices (songs, interviews, and familial figures) are made audible and reworked into a political reading of rights, labor, and access to public space. The study shows how the essay form operates as a site for shifting norms and for …

A Study Of Metaphor In Some Fassi Expressions, Bouchra Berrada

Faits de Langue et Société (FLS)

The metaphor remains the queen of linguistic figures where words are used with another meaning rather than the proper meaning. Its richness lies in the fact that its field of application expands until it covers all species of words: nouns, verbs, adjectives ... The violation or the disrespect of the laws of categorization does not give any abnormal structures; on the contrary, we have, quite simply, typical, original and metaphorical statements.

A Verbal Deictic To «Dynamize» The State In Berber (Kabyle), Fatsiha Aoumer

Faits de Langue et Société (FLS)

This contribution will be mainly dedicated to the deictic d when used with stative verbs and its ability to ‘energize’ the state they express. From the data of a kabyle variety of Toudja, that of the iԑemranen situated to the north west of Bejaia, it will be shown that, thanks to its kinetics and its actualizing function, this deictic allows the verb that it is used with and which initially expresses a result to shift to the expression of the operation that leads to it.

Family And Power Relations In Abdelhak Serhane’S The Man Who Comes Down From The Mountains, Mohamed Bassim

Faits de Langue et Société (FLS)

Drawing on Abdelhak Serhane’s novel L’homme qui descend des montagnes, this article investigates the family as both a privileged site of socialization and a space where gendered power relations are exercised. Using gender theory as an analytical framework, it uncovers patriarchal mechanisms that structure the father/mother relationship and sustain an unequal hierarchy between the sexes. The father figure is portrayed as authoritarian and violent, asserting mastery over the household, while the mother is confined to silence, obedience, and an internalized dependence. The article argues that the novel functions as a critique of oppressive family norms and invites reflection on the …

Interstices: Languages, Gender, And Symbols In Flux, Nadia Kaaouas

Faits de Langue et Société (FLS)

This volume explores language as a territory of confrontation where the sign becomes a tool of resistance against fixed structures. Through a multidisciplinary approach - ranging from grammatical morphology (Arabic, Berber) to literary semiotics (Khatibi, Ben Jelloun, Serhane)- the authors deconstruct power mechanisms and social norms. By analyzing textual subversion and gender dynamics, this volume offers a critical reflection on the mutations of Maghrebian society and the emergence of an imaginary of emancipation.

Book Review: Assessing Autoethnography: Notes On Analysis, Evaluation, And Craft, Margaret Berg

Journal of Educational Research and Innovation

No abstract provided.

Advocate, Spring 2026, Office Of Development And Alumni Affairs, University Of San Diego School Of Law

Advocate

No abstract provided.

2025-2026 Seventh Annual Alumni Recital: Tinca Belinski ('19) And Guzal Isametdinova ('19 And '21), Tinca Belinschi, Guzal Isametdinova

Alumni Concerts

No abstract provided.

Season 2 Episode 9: Dark Patterns Dark Intentions, Sara Gras

Season 02

This episode features an interview with James Barton, a Seton Hall Law School student and member of the Seton Hall Law Review. We discuss his work-in-progress which focuses on the use of dark patterns and other manipulative design practices in the online sports betting industry.

La Inteligencia Artificial Como Herramienta De La Investigación Artística Transdisciplinaria: Hacia Una Pedagogía Ovrónica, Pablo Alejandro Cabral, Rubén Cantos Leal, Pamela Soledad Jiménez Draguícevic

Artículos científicos

La incorporación de inteligencias artificiales generativas representa una transformación paradigmática en la metodología de investigación en las artes para la educación superior. Este ensayo examina críticamente cómo los modelos de lenguaje de gran tamaño (LLM) pueden integrarse en el proceso pedagógico investigativo como socios estratégicos, más que como simples herramientas de consulta. A partir de una experiencia didáctica implementada en la materia de Metodología de la Investigación con estudiantes de la Licenciatura en Actuación de la Facultad de Artes de la Universidad Autónoma de Querétaro, se propone una metodología estructurada en tres fases: exploración temática y contextual, análisis conceptual e …