Digital Commons Network^™

Development Of A Decision-Making Framework For Selecting A Project Delivery Method For Public Sector Construction Projects In Malaysia, Mohd Idham Mohd Noor

Student Works (2020-2029)

Public sector construction projects play a crucial role in economic development and public service delivery, requiring effective project management to ensure optimal public expenditure and successful outcomes. Selecting an appropriate Project Delivery Method (PDM) is a critical yet unstructured process in the Malaysian public sector, influenced by various constraints such as administrative regulations, stakeholder interests, and policy compliance. Despite existing studies on PDM decision-making, research on Malaysia’s public sector remains limited. This study aims to develop a decision-making mechanism for determining appropriate PDM for Malaysia's public sector construction projects. The research adopts an interpretivist approach using a qualitative multiple-case study …

Ownership Structure And Corporate Tax Avoidance In Malaysia: The Moderating Role Of Multinational Corporation Status, Tan Shu Qi

Student Works (2020-2029)

This study examines the relationship between ownership structure and corporate tax avoidance among Malaysian publicly listed firms, with particular emphasis on the moderating role of multinational corporation (MNC) status. Drawing on agency theory, the study investigates how three ownership types government ownership, managerial ownership, and institutional ownership influence firms’ tax avoidance behaviour. Using a quantitative research design, the study analyses panel data from 885 non-financial companies listed on Bursa Malaysia’s Main Market over the post-COVID-19 period from 2021 to 2023. Tax avoidance is proxied using adjusted effective tax rates (ETRadjusted), and panel regression techniques are employed to test the hypothesised …

Betty Ruth Grant

African American Funeral Programs

Funeral program for Betty Ruth Grant. Service was held on February 10, 2026 in Statesboro, Georgia.

Spartan Daily, February 10, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 8

Hyperdensity On Head Ct—An Imaging Review, Ramsis Benjamin, Christian Menard, Erik Larson

School of Medicine Publications

The 3D images derived from non-contrast Computed Tomography (NCCT) scans provide a glimpse into the intra- and extracranial structures, based on the ability of electromagnetic X-rays to penetrate through various tissue densities. The gray matter, for example, possesses a higher density than the white matter, absorbs more X-rays, allows less penetration (attenuation), and thus has larger Hounsfield units (HU), the mathematical value of attenuation coefficient. The CT scanner’s wide availability and ease of use allow for quick assessment of acute neurosurgical abnormalities, such as hemorrhages, mass effect, hydrocephalus, and traumatic injuries. An attenuation value of +60 to +90 HU generally …

Decitabine-Cedazuridine In Patients With Mds And Tp53 Mutations, Samuel Urrutia, Koji Sasaki, Alex Bataller, Hagop Kantarjian, Guillermo Montalban-Bravo, Elizabeth A Griffiths, Amer Zeidan, Michael Savona, Aram Oganesian, Yuri Sano, Harold N Keer, Guillermo Garcia-Manero

Faculty, Staff and Student Publications

No abstract provided.

Channel Gating In Bacteriorhodopsin-Like Channelrhodopsins With Contrasting K+ And Na+ Selectivity, Oleg A Sineshchekov, Elena G Govorunova, Hai Li, Yumei Wang, John L Spudich

Faculty, Staff and Student Publications

Two closely homologous channelrhodopsins from Hyphochytrium catenoides, known as HcKCR1 (kalium channelrhodopsin 1) and HcCCR (cation channelrhodopsin), exhibit >100 times different K+/Na+ relative permeabilities and are emerging optogenetic tools for controlling neurons and cardiomyocytes. Key residue motifs and trimeric organization relate them structurally to bacteriorhodopsin-like cation channelrhodopsins (BCCRs). Here, we demonstrate that they utilize a specific gating mechanism previously suggested for the earlier-discovered BCCR from cryptophytes. Using a comparative analysis of transient absorption changes and photocurrents under single-turnover conditions, we identified an early, far-UV-absorbing photocycle intermediate that precedes channel opening in wild-type HcKCR1 and HcCCR. The UV-absorbing product is a …

Molecular Determinant Of Low-Voltage Dependence Of Human Nav17 Inactivation Revealed By Efficacy-Based Nav17 Selective Inhibitor, Qinglian Tang, Zhengyu Cao

Faculty, Staff and Student Publications

Nav1.7 is a voltage-gated sodium channel (VGSC) subtype predominantly expressed in sensory neurons, amplifying threshold currents. Here, we identify that Uvarigranol D (UGD) suppresses human (h) Nav1.7 with a much greater maximal inhibition than other VGSC subtypes, despite having similar apparent affinities. We demonstrate that Thr1398 determines the greater inhibitory efficacy of UGD, the leftward shift in voltage-dependence and faster inactivation kinetics of hNav1.7. UGD binds to the inactivated state, with Gln360, Ile394, Lys1395, Phe1737, and Tyr1744 being critically involved. Moreover, while UGD suppresses action potentials in both rat dorsal root ganglion neurons and human induced pluripotent stem cell-derived cardiomyocytes, …

The Gossett Protocol: A 120-Point Master Engineering Standard For Sovereign Neural-Interface Bypasses, Jon S. Gossett

Defensive Publications Series

This disclosure establishes a comprehensive 120-point industrial engineering standard for a semi-invasive digital spinal bypass and neural communication bridge. The protocol prioritizes "Human Sovereignty" through a hardware-locked, 16-bit discrete metadata standard, ensuring all motor intent is processed locally without cloud dependency. Key technical innovations include a 1.0mm non-penetrative cortical clearance zone, a medical-grade 850nm NIR optical bridge for transdermal signal transmission, and a 38.5°C thermal breach auto-kill safety wall. Version 6.2 introduces Category IX, detailing a "Camera-Assisted Grounding" process where external optical sensors are utilized exclusively for initial dictionary calibration and intent verification. This optical requirement is phased out once …

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Heme And Hemozoin Induce Platelet Cell Death Through Upr-Induced Apoptosis And Ferroptosis In Vivax Malaria, Milena Tavares Gomes, Robert A Campbell, Et Al.

2020-Current year OA Pubs

Malaria is a highly prevalent infectious disease caused by Plasmodium parasites. Plasmodium intraerythrocytic replication leads to hemolysis-driven intermittent febrile crises in patients. In addition, the lysis of unparasitized red blood cells contributes to anemia and endotoxemia. Because thrombocytopenia is an important feature of vivax and severe falciparum malaria, we hypothesized that increased hemolysis in malaria contributes to severe thrombocytopenia by releasing endogenous and parasite toxins (ie, heme and hemozoin) capable of inducing programmed cell death in platelets. Using complementary biochemical, ultrastructural, pharmacological, and molecular approaches, we examined response to stress and cell death pathways that were elevated in the transcriptome …

Outcomes Following Matched Sibling Donor Transplantation For Severe Combined Immunodeficiency: A Report From The Pidtc, Ahmad Rayes, Jeffrey J Bednarski, Et Al.

2020-Current year OA Pubs

The Primary Immune Deficiency Treatment Consortium performed a retrospective analysis of 133 patients with severe combined immunodeficiency (SCID) receiving matched sibling donor (MSD) hematopoietic cell transplantation (HCT) between 1980 and 2023 at 30 North American institutions. In this largest cohort of MSD outcomes in patients with SCID to date, we examined the impact of conditioning regimen and graft-versus-host disease (GVHD) prophylaxis on survival and immune recovery. Outcomes after MSD HCT for SCID were excellent. Patients without an active infection or failure to thrive (FTT) at the time of HCT had 5-year overall survival superior to those with infection or FTT. …

Derivation And External Validation Of A Venous Thromboembolism Risk Prediction Model In Asparaginase-Treated All, Daniela R Anderson, Kristen Sanfilippo, Et Al.

2020-Current year OA Pubs

The incidence of venous thromboembolism (VTE) in patients with acute lymphoblastic leukemia (ALL) receiving asparaginase-based induction is high despite primary thromboprophylaxis. Our aim was to derive and externally validate a VTE risk prediction model in patients with ALL receiving asparaginase-based induction. We conducted a multicenter retrospective cohort study of patients (aged ≥18 years) with newly diagnosed ALL receiving asparaginase-based induction. The derivation and external validation cohorts included 306 and 94 patients, respectively. Primary outcome was VTE at any site. A cause-specific Cox proportional hazards model stratified by thromboprophylaxis and center was performed to identify VTE risk factors in the derivation …

Smoldering Multiple Myeloma In The United States: A Population-Based Analysis, Shi-Yi Wang, Rong Wang, Martin Schoen, John H Huber, Eric J Feuer, Jennifer Ruhl, Natalia Neparidze, Xiaomei Ma, Amy J Davidoff, Su-Hsin Chang

2020-Current year OA Pubs

No abstract provided.

Decitabine-Cedazuridine In Patients With Mds And Tp53 Mutations, Samuel Urrutia, Koji Sasaki, Alex Bataller, Hagop Kantarjian, Guillermo Montalban-Bravo, James Mccloskey, Elizabeth A Griffiths, Karen Yee, Amer Zeidan, Michael Savona, Aram Oganesian, Yuri Sano, Harold N Keer, Guillermo Garcia-Manero

2020-Current year OA Pubs

No abstract provided.

Staff Education On Motivational Interviewing And Culturally Responsive Education To Reduce No-Shows And Appointment Cancellations, Aisha Adigun

Walden Dissertations and Doctoral Studies

No-show and late appointment cancellations remain significant challenges in outpatient psychiatry clinics, negatively impacting continuity of care, clinic efficiency, and patient outcomes. Motivational interviewing (MI) and culturally responsive communication are evidence-based approaches that support patient engagement and understanding, yet they are not consistently incorporated into staff education related to appointment adherence. This project evaluates whether staff education on MI and culturally responsive communication increases staff knowledge and skills in educating patients about no-show and appointment cancellation policies and whether this education contributes to improved appointment attendance. A pre–post intervention design will be used in an outpatient psychiatry clinic. Clinical and …

A Quantitative Analysis Of Corporate Social Responsibilities In Ghana, Musah Dumah, Juliet Yaa Boateng

Business Management Review

This study investigates the impact of corporate social responsibility (CSR) on financial performance of banks on the Ghana Stock Exchange from 2019-2023. The research used a descriptive approach and the panel data regression analysis to examine how social, environmental, and economic dimensions of CSR influence Return on Assets (ROA), Capital Adequacy Ratio (CAR) and Return on Equity (ROE). The results indicate significant positive link between social and environmental dimensions of CSR and both ROA and ROE, which aligned with both the stakeholder and the resource-based view (RBV) theories as these theories talk about serving the interest of stakeholders and efficient …

Drg Explant Model For Understanding Mechanism Of Oxaliplatin-Induced Peripheral Neuropathy And Identifying Potential Therapeutic Targets, Junwei Du, Leland C Sudlow, Igor D Luzhansky, Mikhail Y Berezin

2020-Current year OA Pubs

Oxaliplatin-triggered chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of cancer treatment that limits the efficacy of chemotherapy and negatively impacts patients' quality of life dramatically. To better understand the mechanisms of CIPN and to screen for potential therapeutic targets, it is critical to have reliable in vitro assays that effectively mirror the neuropathy in vivo. In this study, we established a dorsal root ganglia (DRG) explant model. This model displayed dose-dependent inhibition of neurite outgrowth in response to oxaliplatin, while oxalic acid exhibited no significant impact on the regrowth of DRG. The robustness of this assay …

Discovery Of Horsfieldia Macrothyrsa Bioactives With Cytotoxic Effects On Breast Cancer Cells Through In Vitro And Docking Analyses, Megawati Megawati, Akhmad Darmawan, Agus Budiawan Naro Putra, Kartika Dyah Palupi, Marissa Angelina, Ahmad Randy, Siska Andrina Kusumastuti, Faris Hermawan, Sumi Hudiyono

Karbala International Journal of Modern Science

This study investigated the phytochemical constituents and biological activities of Horsfieldia macrothyrsa leaves to identify their bioactive compounds. Methanol extracts were fractionated using n-hexane and ethyl acetate, followed by silica gel column chromatography with a stepwise polarity gradient. From 100 g of powdered leaves, three major    compounds were successfully isolated from the ethyl acetate fraction: 1-(2,4,6-trihydroxyphenyl)dodecan-1-one (1), sesamin (2), and β-sitosterol (3). Their chemical structures were confirmed using UV, IR, LC–MS/MS, and NMR  spectroscopy. Biological activities of the fractions and isolates were evaluated through DPPH antioxidant assays, α-glucosidase inhibition for antidiabetic activity, MTT …

Data Management Plans For Grant Proposals, Rubab Shahzad

Day Family Research Lab Workshop Series

Fundamentals of research data management and how to create effective Data Management Plans (DMPs) and Data Management Sharing Plans (DMSP)

Inside Aurora Sinai Medical Center, 2004 January, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.

Inside Aurora Sinai Medical Center, 2004 February, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.

Inside Aurora Sinai Medical Center, 2004 March, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events. This issue introduces the Planetree plan for Aurora hospitals.

Inside Aurora Sinai Medical Center, 2004 April, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.

Inside Aurora Sinai Medical Center, 2004 May, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events. This issue has a feature on the NICU.

Inside Aurora Sinai Medical Center, 2004 June, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.

Inside Aurora Sinai Medical Center, 2004 July, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.

Inside Aurora Sinai Medical Center, 2004 August, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.

Inside Aurora Sinai Medical Center, 2004 September, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.

Inside Aurora Sinai Medical Center, 2004 October, Advocate Health - Midwest

Historical Documents - Combined

Aurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.

This is the last issue of this newsletter with this title. It continues as Aurora Sinai Exchange.

Orientation-Specific Surface Response Of Shot Peening In Laser Powder Bed Fusion Ti-6al-4v Parts, Sivasubramanian Chandramouli, Michael S. Titus, Michael P. Sealy

Purdue Polytechnic Graduate Student Poster Symposium

Critical aerospace components, such as turbine blades and landing gears, are increasingly produced using additive manufacturing (AM), especially laser-powder-bed-fusion (LPBF) due to its design flexibility. However, the inherent high surface roughness and tensile residual stresses in LPBF parts compromise performance and dimensional stability. Shot peening, a surface work-hardening process, is an effective post-processing solution.

The research objective is to understand the surface strengthening effect from grain refinement by inhomogeneous elastic-plastic deformation across surface orientations (0-90°) in AM parts. Peening parameters, specifically coverage and peening angle, are optimized to mitigate orientation-dependent surface properties in LPBF Ti64. Under optimized conditions, shot peening …