Digital Commons Network^™

Mdma And Mouth Ulcers, Y Lin

Peninsula Dental School

Sir, 3,4-methylenedioxymethamphetamine (MDMA), otherwise known as ecstasy, is an illicit drug which is consumed for recreational use. In addition to systemic complications, it can also present with a variety of oral side effects. Patients may first present to their primary care practitioners before being referred acutely onwards to an oral and maxillofacial surgery or oral medicine department for further investigations and management, which has been our experience here in a secondary care setting. I would like to raise awareness about these oral manifestations and the management options that can be provided.Xerostomia can occur which should subside after approximately 48 hours. …

A Review Of Dna Risk Alleles To Determine Epigenetic Repair Of Mrna Expression To Prove Therapeutic Effectiveness In Reward Deficiency Syndrome (Rds): Embracing "Precision Behavioral Management", Kenneth Blum, Bruce Steinberg, Marjorie C Gondre-Lewis, David Baron, Edward J Modestino, Rajendra D Badgaiyan, B William Downs, Debasis Bagchi, Raymond Brewer, Thomas Mclaughlin, Abdalla Bowirrat, Mark Gold

2020-Current year OA Pubs

This is a review of research on "Precision Behavioral Management" of substance use disorder (SUD). America is experiencing a high prevalence of substance use disorder, primarily involving legal and illegal opioid use. A 3000% increase in treatment for substance abuse has occurred between 2000 and 2016. Unfortunately, present day treatment of opioid abuse involves providing replacement therapy with powerful opioids to, at best, induce harm reduction, not prophylaxis. These interventions do not enhance gene expression and restore the balance of the brain reward system's neurotransmitters. We are proposing a generalized approach called "Precision Behavioral Management". This approach includes 1) using …

Program At Uab Helps Preserve Limbs In Patient With Diabetes, Staff

Browse All News

No abstract provided.

New Gene Therapy Could Provide Cure For Sickle Cell Disease, According To Uab Study, Adam Pope

Browse All News

No abstract provided.

Financial Facts From The Seed For Oklahoma Kids Child Development Account Experiment, Center For Social Development

Center for Social Development Research

How does a Child Development Account (CDA) opened at a child’s birth shape their access to assets for higher education?

This Fact Sheet highlights findings from Financial Outcomes in a Child Development Account Experiment: Full Inclusion, Success Regardless of Race or Income, and Investment Growth for All (CSD Research Summary 21-06). Products of the SEED for Oklahoma Kids (SEED OK) experiment, both the Fact Sheet and the Research Summary indicate that the automatic CDA in SEED OK greatly increases the likelihood that disadvantaged children have assets for their future education. When given a CDA structure and support for …

Oral Care Experiences Of Palliative Care Patients, Their Relatives/Carers And Healthcare Professionals: A Qualitative Systematic Review, Delgado M Bernardes, Anastasios Plessas, Lorna Burns, Helen Neilens, Sarah Griffiths, Jos Latour

Peninsula Dental School

No abstract provided.

Air Quality And Mental Health: Evidence, Challenges And Future Directions, K Bhui, J Newbury, R Latham, M Ucci, Z Nasar, B Turner, C O'Leary, Hl Fisher, E Marczylo, P Douglas, S Stansfeld, S Jackson, S Tyrrel, A Rzhetsky, R Kinnersley, P Kumar, C Duchaine, F Coulon

School of Biomedical Sciences

No abstract provided.

Age Related Dementias, Shahab Soltani

Chemistry and Biochemistry

During the last few decades, the average life expectancy has dramatically increased in the U.S.A. and globally. As a result, the diseases associated with age, such as dementia, significantly impact families, society, and government. Dementia is a broad term describing memory loss, cognitive dysfunctions, and limited social skills caused by many factors such as aging, stroke, and genetic background. Although the primary etiology remains unclear but inflammatory reactions, neurodegeneration, vascular abnormalities play an important role in the progression of these disorders. Therefore, treatment is mainly supportive to relieve the symptoms of dementia and not to cure dementia or slow down …

3t3-L1 Adipocytes As A Model Of Glut4 Translocation, Aline Collin

Chemistry and Biochemistry

Type 2 diabetes (T2D), a lethal disease, reveals an alarming increase of epidemic proportions and, by 2050, an estimated 1 in 3 adults in the US will suffer from it. Persistent and systemic inflammatory and oxidative stress in adipose tissue and skeletal muscle are recognized as key players in the progression of T2D. T2D is characterized by insulin resistance, the inability of cells to respond to standard circulating levels of insulin, resulting in hyperglycemia. In adipocytes and skeletal muscle, glucose uptake, a vital step in blood glucose regulation, predominantly occurs via the glucose transporter 4 (Glut4) in an insulindependent recruitment …

Steroid Receptor-Coregulator Transcriptional Complexes: New Insights From Cryoem, Bert W O'Malley

Faculty, Staff and Students Publications

Steroid receptors activate gene transcription through recruitment of a number of coregulators to facilitate histone modification, chromatin remodeling, and general transcription machinery stabilization. Understanding the structures of full-length steroid receptor and coregulatory complexes has been difficult due to their large molecular sizes and dynamic structural conformations. Recent developments in cryo-electron microscopy (cryoEM) technology and proteomics have advanced the structural studies of steroid receptor complexes. Here, we will review the insights we learned from cryoEM studies of the estrogen and androgen receptor transcriptional complexes. Despite similar domain organizations, the two receptors have different coregulator interaction modes. The cryoEM structures now have …

Celebrating Alutiiq Cultural Revitalization: Pathways To Holistic Individual Health And Community Wellness, Margaret Susan Mete

Indigenous Studies

It is well understood that disease is a consequence of varied causation. Despite the fact that many health care providers acknowledge the importance of treating patients in a comprehensive manner in order to successfully cure sickness or alleviate symptoms, the contemporary medical system dispenses care in a fragmented and frequently incomplete manner. The essential differences between Indigenous epistemologies and the predominant Western worldview has had a more devastating impact on well-being and infirmity than is often recognized. The intention of this research is to explore the importance of promoting balanced holistic health care at a deeper and more essential level …

Chromatic Quasisymmetric Class Functions For Combinatorial Hopf Monoids, Jacob A. White

School of Mathematical & Statistical Sciences Faculty Publications

We study the chromatic quasisymmetric class function of a linearized combinatorial Hopf monoid. Given a linearized combinatorial Hopf monoid H, and an H-structure h on a set N, there are proper colorings of h, generalizing graph colorings and poset partitions. We show that the automorphism group of h acts on the set of proper colorings. The chromatic quasisymmetric class function enumerates the fixed points of this action, weighting each coloring with a monomial. For the Hopf monoid of graphs this invariant generalizes Stanley's chromatic symmetric function and specializes to the orbital chromatic polynomial of Cameron and Kayibi.

We also introduce …

Influence Of Grassland Management And Grazing By Different Farm Animals On Animal Performance And Flora Alterations, W. Jentsch, H.-D. Matthes, A. Admasu, H. Möhring

IGC Proceedings (1977-2023)

The objectives of this study were to test the possibilities of using different farm animals for landscape care on extensive pasture, taking into account their particular performance, and to analyse alterations of the flora in consequence of grazing by different animals and various pasture management. Salers had the highest (836g/d) and Galloways (584g/d) the lowest live weight gain as compared with the other breeds (771g/d). Lambs had higher live weight when grazing together with cattle and horses (mixed grazing) than under one species grazing. The number of legume increased and that of grass decreased. Following 3 years the grazing animals …

Animal Production From Tropical Pastures Renovated By Subsoiling And Fertilization In The Cerrados Of Brazil, Valéria P. B. Euclides, Manuel C. M. Macedo, M. P. Oliveira

IGC Proceedings (1977-2023)

A grazing trial was conducted, to study the effects of fertilization on the maintenance of the productivity of four tropical grasses. The paddocks were subsoiled, and dived into halves: one (LF1) received 400 kg/ha of a fertilizer formula 0-20-20.and the other (LF2) 800 kg/ha of the same fertilizers, in January 1995. Annually, 50 kg/ha of N was applied. The productivity on LF2 pastures was greater than that on FL1 pastures, averaging 520 and 410 kg of liveweight gain/ha/year. A double strategy should be followed to sustain animal production in the savanna: maintain soil P over a critical value of 3.0 …

Performance Of Nellore Cattle Under Two Grazing Management Systems, L. De A. Corrêa, Maurício M. De Alencar, Rogério T. Barbosa, P. F. Barbosa, Geraldo M. Da Cruz, I. U. Packer, C. A. Cordeiro

IGC Proceedings (1977-2023)

The objective of this study was to evaluate the effects of grazing intensification on birth weight (BW), weaning weight (WW, standartized to 205 days), average daily gain from birth to weaning (ADG), and gestation length (GL) of calves, cow weight at calving (CWC) and at weaning (CWW), cow condition score at calving (CCC) and at weaning (CCW), and BW/CWC (BWR), WW/CWC (WWRC) and WW/CWW (WWRW) ratios. One hundred and sixty eight Nellore calves born in 1998 and 1999, out of dams maintained in two grazing management systems were evaluated: an extensive 1.0 animal unity (AU). ha^-1 system on unfertilized …

Orchardgrass Pastures For Early-Weaned Beef Calves, J. C. Waller, H. A. Fribourg, C. Dixon, A. E. Fisher, B. V. Conger

IGC Proceedings (1977-2023)

Orchardgrass (Dactylis glomerata) grown alone or with ladino white (Trifolium repens) and red (T. pratense) clovers, provides a high quality March to June pasture. However, many beef producers have their cows calving in January-March, thus producing offspring that are too young to utilize spring forage well. As an alternative, some producers have their cows bred so that calves are born in autumn (September-November). By spring, these calves are old enough to consume pasture forage. The few earlier studies on early weaning of fall-born calves consist of drylot feeding of high quality hay or concentrates. …

中小学英语学术词汇标准参照测验的开发及验证, Christopher D. Barr, Diane August, Lauren Artzi, Coleen D. Carlson, David J. Francis

Chinese/English Journal of Educational Measurement and Evaluation | 教育测量与评估双语期刊

本研究开发了一项英语学术词汇测验 (the Test of Academic Vocabulary in English, TAVE)，并报告了TAVE的设计和验证过程。该测验旨在衡量学生对学术词汇的掌握情况，不同年级题本之间进行了垂直等值，而且评定结果可以统一到同一个发展性的量尺 (a developmental scale) 之上。此外，测验分数可以向一个有意义的语料库 (a meaningful corpus) 中推广。本研究以先前的试点工作为基础，所用样本包含2,238名来自西南某大城市的3到8年级学生，当中既有英语学习者 (English learner, EL)，也有非英语学习者，并阐述了语料库与测验的开发思路及过程。结果表明，TAVE测验呈现单维结构且具有很高的信度和关联效度，测验也能很好地区分低年级之间学生的词汇掌握能力。本文研究意义在于提出了一种发展性的度量方法 (a developmental metric)，使得学生的测验分数可以推广到一个有意义的语料库中——该语料库涵盖了学术文本中的常见词汇，而且能获得学生对语料库各单词的掌握概率。本文实践意义在于提供了一个不同年级分数可比的测验工具，并能用它来追踪学生短期或长期上词汇量的变动。

Designing And Validating A Criterion-Referenced Assessment Of High Utility Academic Vocabulary In English For Elementary And Middle School Students, Christopher D. Barr, Diane August, Lauren Artzi, Coleen D. Carlson, David J. Francis

Chinese/English Journal of Educational Measurement and Evaluation | 教育测量与评估双语期刊

This study reports on the design and validation of a vertically equated assessment of academic vocabulary that generalizes to a meaningful corpus of words and is measured on a developmental scale: the Test of Academic Vocabulary in English (TAVE). The study builds on previous pilot work and uses a larger sample of students who are English learners (ELs) and non-EL students in grades 3 to 8 (n= 2,238) from a large urban Southwestern region, and describes the rationale and process of corpus and assessment development. A review of the findings from the study found the academic vocabulary construct …

以数据挖掘的方式探索区分高低数学素养表现学生之因素——以澳门社经弱势及优势背景学生为例, Wa Kit Sou, Kwok Cheung Cheung, Man Kai Ieong, Soi Kei Mak

Chinese/English Journal of Educational Measurement and Evaluation | 教育测量与评估双语期刊

澳门PISA 2012报告显示，它是教育优质且公平的经济体，然而社经弱势学生要取得成功普遍较优势学生困难，教育公平的系统中可能存在不公平现象。本研究分别从澳门PISA 2012社经弱势和优势学生的评核数据，挖掘出区分弱势低表现生和弱势高表现生，以及区分优势低表现生和优势高表现生的重要学习因素。本研究的发现能够更好地了解澳门相对于其它数学素养高表现地区教育优质和公平的原因，同时也揭露了教育公平系统出现轻微不公平现象的症结所在。

Using Data Mining To Explore Factors That Distinguish Between Students With High And Low Mathematical Literacy Performance — An Example With Socio-Economically Disadvantaged And Advantaged Students In Macao, Wa Kit Sou, Kwok Cheung Cheung, Man Kai Ieong, Soi Kei Mak

Chinese/English Journal of Educational Measurement and Evaluation | 教育测量与评估双语期刊

Using Macao-PISA 2012 data collected from socio-economically disadvantaged and advantaged students, this study identified two sets of important learning factors that distinguished between low- and high-performing disadvantaged students, and between low- and high-performing advantaged students, respectively. The findings of this research contribute to a better understanding of the reasons for Macao’s high-quality and equitable education as compared to other regions with high mathematical literacy performance while also revealing the crux of small inequities in its education system. The analysis method used in this paper provides a paradigm for data mining research using large-scale assessment data and helps researchers better grasp …

One Vote, Two Votes, Three Votes, Four: How Ranked Choice Voting Burdens Voting Rights And More, Brandon Bryer

University of Cincinnati Law Review

No abstract provided.

"You Should Have Known:" The Need For Evidentiary Notice Requirements In Immigration Court, Marisa Moore Apel

University of Cincinnati Law Review

No abstract provided.

Trick Or Treat? How A U.S. Patent Over A Method For Processing Sugarcane Wrongly Alarmed The Colombian Panela Industry, Carter Ostrowski

University of Cincinnati Law Review

No abstract provided.

Innocent Until Suspected Guilty, Rebekah Durham

University of Cincinnati Law Review

No abstract provided.

Revitalizing The Ban On Conversion Therapy: An Affirmation Of The Constitutionality Of Conversion Therapy Bans, Logan Kline

University of Cincinnati Law Review

No abstract provided.

Rejecting Word Worship: An Integrative Approach To Judicial Construction Of Insurance Policies, Jeffrey W. Stempel, Erik S. Knutsen

University of Cincinnati Law Review

Insurance coverage litigation is a quest for discerning meaning: Does the insurance policy cover the loss at issue? Construing the insurance policy, courts attempt to give legal effect to what the document purports to command. But what were the intentions and expectations of insurer and insured? Do those intentions even matter? Or is only the written text of the policy relevant to the coverage result? Courts addressing these questions typically frame the interpretative choice as one of strict textualism versus contextual functionalism.

In many, perhaps even most situations, text and context align to create an “easy” case. If a factory …

Political Equality And First Amendment Challenges To Labor Law, Luke Taylor

University of Cincinnati Law Review

This Article conceptualizes a novel basis for defending laws that strengthen labor unions from First Amendment challenge: the argument that these laws are adequately tailored to advancing a compelling state interest in reducing economic inequality’s transmission into political inequality. The Article makes two principal contributions. First, it updates criticisms of the Supreme Court’s campaign finance decisions’ rejection of any compelling interest sounding in political equality. The Article does so by bringing recent constitutional scholarship to bear on that criticism and by explaining how recent improvements in social scientists’ ability to track different economic brackets’ political influence call for the Court …

Challenging Solitary Confinement Through State Constitutions, Alison Gordon

University of Cincinnati Law Review

Eighth Amendment jurisprudence has resulted in limited scrutiny of solitary confinement despite the known harms associated with the practice. The two-part test established by the federal courts to evaluate Eighth Amendment claims and limitations on challenging prison conditions under the Prison Litigation Reform Act can make it difficult to establish that solitary confinement is cruel and unusual punishment.

State constitutional challenges to solitary confinement are underexplored. Nearly all state constitutions contain an equivalent provision to the Eighth Amendment’s prohibition on cruel and unusual punishment. State courts need not be bound by federal jurisprudence in interpreting the scope of the state …

Authority, Obedience, And Justification, Michelle Madden Dempsey

University of Cincinnati Law Review

We have a duty to think for ourselves. The law claims authority over us. We have a duty, at least sometimes, to obey the law. Alone, each of these premises is fairly uncontroversial. Combined, they create some intriguing puzzles. Can law’s claim of authority be justified? If so, does justified legal authority entail an obligation to obey the law? If not, are we nonetheless justified, and perhaps even obligated, to act as if such an obligation exists? While this essay is hardly the first to address these questions, it is the first to do so by combining elements of Joseph …

Moby-Dick As Corporate Catastrophe: Law, Ethics, And Redemption, David Yosifon

University of Cincinnati Law Review

Herman Melville’s Moby-Dick serves here as a vehicle through which to interrogate core features of American corporate law and excavate some of the deeper lessons about the human soul that lurk behind the pasteboard mask of the law’s black letter. The inquiry yields an illuminating vantage on the ethical consequences of corporate capital structure, the law of corporate purpose, the meaning of voluntarism, the ethical stakes of corporate fiduciary obligations, and the role of lawyers in preventing or facilitating corporate catastrophe. No prior familiarity with the novel or corporate law is required.