Digital Commons Network^™

Putative Concussion Biomarkers Identified In Adolescent Male Athletes Using Targeted Plasma Proteomics, Michael R. Miller, Michael Robinson, Lisa Fischer, Alicia Dibattista, Maitray A. Patel, Mark Daley, Robert Bartha, Gregory A. Dekaban, Ravi S. Menon, J. Kevin Shoemaker, Eleftherios P. Diamandis, Ioannis Prassas, Douglas D. Fraser

Medical Biophysics Publications

Sport concussions can be difficult to diagnose and if missed, they can expose athletes to greater injury risk and long-lasting neurological disabilities. Discovery of objective biomarkers to aid concussion diagnosis is critical to protecting athlete brain health. To this end, we performed targeted proteomics on plasma obtained from adolescent athletes suffering a sports concussion. A total of 11 concussed male athletes were enrolled at our academic Sport Medicine Concussion Clinic, as well as 24 sex-, age- and activity-matched healthy control subjects. Clinical evaluation was performed and blood was drawn within 72 h of injury. Proximity extension assays were performed for …

An Examination Of Perceptions Of Intimate Partner Violence Severity Within Same-Sex Compared To Opposite-Sex Couples, Eric K. Frazier

ETD Archive

Background: About 1 in 4 women and 1 in 10 men have experienced intimate partner violence (IPV; CDC, 2019). Although there have been numerous studies on IPV, our knowledge pertains to IPV in heterosexual couples. Although IPV occurs at similar rates in both opposite and same sex couples, studies suggest that individuals are more likely to evaluate IPV in opposite-sex couples as more severe compared to same-sex couples. Therefore, the purpose of this study was to examine college students’ perceptions of IPV in both opposite-sex and same-sex couples. Procedure: The study included 144 participants who read eight vignettes, four of …

Teaching Computer Science Csc 222, Harrison Dekker

Library Impact Statements

No abstract provided.

Cryptococcus Neoformans Melanization Incorporates Multiple Catecholamines To Produce Polytypic Melanin, Rosanna P. Baker, Christine Chrissian, Ruth E. Stark, Arturo Casadevall

Publications and Research

Melanin is a major virulence factor in pathogenic fungi that enhances the ability of fungal cells to resist immune clearance. Cryptococcus neoformans is an important human pathogenic fungus that synthesizes melanin from exogenous tissue catecholamine precursors during infection, but the type of melanin made in cryptococcal meningoencephalitis is unknown. We analyzed the efficacy of various catecholamines found in brain tissue in supporting melanization using animal brain tissue and synthetic catecholamine mixtures reflecting brain tissue proportions. Solid-state NMR spectra of the melanin pigment produced from such mixtures yielded more melanin than expected if only the preferred constituent dopamine had been incorporated, …

Raven Leilani Named Grisham Writer-In-Residence, Edwin B. Smith

University of Mississippi News

Prize-winning author to teach course, lecture during spring 2022 semester

Usa V. Khalil Stafford

2021 Decisions

USDC for the District of New Jersey

Real-World Impact Of Fremanezumab On Migraine Symptoms And Resource Utilization In The United States, Peter Mcallister, Lois Lamerato, Lynda J. Krasenbaum, Joshua M. Cohen, Krishna Tangirala, Stephen Thompson, Maurice Driessen, Julian Casciano, Zenobia Dotiwala, Alexander Mauskop

Public Health Sciences Articles

BACKGROUND: Fremanezumab, a fully humanized monoclonal antibody (IgG2Δa) that selectively targets calcitonin gene-related peptide (CGRP), is approved for migraine prevention in adults. Real-world data on the effectiveness of fremanezumab are limited. This retrospective, observational cohort study assessed patient-reported migraine symptoms, health care resource utilization (HCRU), and direct medical costs before and after fremanezumab treatment initiation.

METHODS: Data were extracted from September 2018 through June 2020 from the Midwest component of EMRClaims+®, an integrated health services database containing > 20 million medical records from national commercial insurance claims, Medicare claims, and regional electronic medical records. Patients included in the cohort analysis were …

Masthead

New England Classical Journal

No abstract provided.

Secret Sharing And Its Variants, Matroids,Combinatorics., Shion Samadder Chaudhury Dr.

Doctoral Theses

The main focus of this thesis is secret sharing. Secret Sharing is a very basic and fundamental cryptographic primitive. It is a method to share a secret by a dealer among different parties in such a way that only certain predetermined subsets of parties can together reconstruct the secret while some of the remaining subsets of parties can have no information about the secret. Secret sharing was introduced independently by Shamir [139] and Blakely [20]. What they introduced is called a threshold secret sharing scheme. In such a secret sharing scheme the subsets of parties that can reconstruct a secret …

Dr. Gerald Keown Remembered By Gwu Community For His Passion To Teach And Serve, Office Of University Communications

Gardner-Webb NewsCenter Archive

The Gardner-Webb University community is remembering the contributions and legacy of Dr. Gerald Keown, who passed away on Dec. 14. Keown was professor emeritus of Biblical Studies and the former associate dean of the Gardner-Webb University M. Christopher White School of Divinity. He began his tenure at GWU in 1996 as a professor of Old Testament Interpretation and served as associate dean from 2006 to 2019.

To Lift Or Not To Lift: An Institutional Ethnography Of Patient Handling Practices, Hans-Peter De Ruiter

Dissertations

The handling (lifting, mobilizing, moving etc) of patients is an integral part of the carework in health-care institutions. For obvious reasons, this puts healthcare providers at risk for musculoskeletal injuries (MSIs); furthermore the risk of such injuries has been considered an inherent risk of care work. In the last decade a concerted effort has been made to decrease (with the goal of eliminating) caregiver injuries by implementing safe patient handling programs (SPHP). These programs are presented as evidence-based algorithms that require the use of mechanical lifting devices. Institutions implement SPHPs as policies and procedural guidelines to which caregivers must conform. …

Quality Of Life Among Children With Physical Disabilities, Sharron E. Guillett

Dissertations

A triangulated descriptive research design was used to examine the relationships between quality of life (QOL), health status and physical disability among children between the ages of 8 and 15. A non-random sample (N = 80) of children with and without physical disabilities and their parents participated in this exploratory study. Children were asked to rank their quality of life from one to ten using a modified version of the Child Health Assessment Ladder (CHASL) (Norton, 1987) and then to discuss the rank they chose. QOL scores did not differ significantly between groups (M = 7 for both groups). Thirty …

Emotional Intelligence, Motivation, And Retention Among Undergraduate Students Attending Associate-Degree Nursing Programs In Illinois, Patricia L. Pence

Dissertations

The purpose of the quantitative, descriptive non-experimental study was to determine what the relationship is between emotional intelligence (EI), motivation, demographic variables, and nursing student retention. The research also tested the Nursing Undergraduate Retention and Success (NURS) model by examining demographic variables and academic motivation of nursing students. The Motivated Strategies for Learning Questionnaire (MSLQ) and the Assessing Emotions Scale (AES) garnered data from 390 first-year undergraduate students attending nine associate degree-nursing (ADN) schools in Illinois. Regression analysis suggested statistically significant differences in the mean scores for the test anxiety and control of learning beliefs MSLQ subscales with retention at …

Evaluating The Impact Of A Mindfulness Intervention On Mindful Attention And Awareness Resilience To Stress, And Perceived Stress In Newly Licensed Nurses In A Nurse Residency Program, Vicki L. Washington

Dissertations

A career in the healthcare profession of nursing provokes significant stress in newly licensed nurses. Previous studies suggested that mindful practice enhanced well-being by bringing awareness to thinking and living in the present moment (being mindful), decreased stress, and enhanced resilience to stress.

The purpose of this study was to evaluate the impact of a mindfulness intervention on mindful attention and awareness, resilience to stress, perceived stress, and health status in newly licensed nurses in a nurse residency program (NRP).

The Relationship Between Self-Efficacy Beliefs Toward Self-Management Of Asthma And Asthma Self-Management Behaviors In Urban African American Children, Teresa Louise Kaul

Dissertations

African American children in the United States are disproportionately affected by childhood asthma. Despite the enormous effort that has gone into developing educational interventions to teach patients and families self-management skills, morbidity and mortality rates continue to rise, especially for the African American child (CDC, 2005). In an attempt to increase understanding of the factors that may influence self-management of chronic disease, this study examined the relationship between asthma self-efficacy belief and asthma self-management in urban African American children. The study, using a descriptive correlational design, surveyed 81 urban African American children age 7-12 years old with self reported asthma. …

Mansouramycins E–G, Cytotoxic Isoquinolinequinones From Marine Streptomycetes, Mohamed Shaaban, Khaled A. Shaaban, Gerhard Kelter, Heinz Herbert Fiebig, Hartmut Laatsch

Center for Pharmaceutical Research and Innovation Faculty Publications

Chemical investigation of the ethyl acetate extract from the marine-derived Streptomyces sp. isolate B1848 resulted in three new isoquinolinequinone derivatives, the mansouramycins E–G (1a–3a), in addition to the previously reported mansouramycins A (5) and D (6). Their structures were elucidated by computer-assisted interpretation of 1D and 2D NMR spectra, high-resolution mass spectrometry, and by comparison with related compounds. Cytotoxicity profiling of the mansouramycins in a panel of up to 36 tumor cell lines indicated a significant cytotoxicity and good tumor selectivity for mansouramycin F (2a), while the activity profile of E ( …

Towers Of Trash: Dissecting India’S Solid Waste Management Crisis, Maya L. Reddy

Student Theses 2015-Present

This paper explores the complex issue of poor solid waste management in the nation of India. The infamous Ghazipur landfill in New Delhi serves as a focal point of this paper as it provides drastic examples of the consequences of solid waste management systems that do not operate effectively. Drawing on information from various scholarly sources, Chapter 1 discusses the issue of solid waste mismanagement in India and its surrounding quantitative and qualitative data. Chapter 2 highlights the socioeconomic, cultural, and religious aspects of consumption, growth, and waste, specifically in relation to prevailing sociological attitudes on material wealth and luxury. …

Does Anyone Remember "Fingerprints On An X-Ray?", Vincent L. Sorrell

Gill Heart & Vascular Institute Faculty Publications

No abstract provided.

2021-December-20-Quillen College Of Medicine Announces New Leadership Appointments, University Marketing And Communication, East Tennessee State University

ETSU News

Dr. David Linville

Dr. Linville will serve as senior associate dean and chief of staff at Quillen College of Medicine and associate vice president for Clinical Affairs at ETSU. His new role begins in January 2022.

JOHNSON CITY (Dec. 20, 2021) — Several individuals have been appointed to new leadership roles at East Tennessee State University’s Quillen College of Medicine.

Dr. David Linville will serve as senior associate dean and chief of staff at Quillen College of Medicine and associate vice president for Clinical Affairs at ETSU. His new role begins in January 2022.

“Dr. Linville is well known …

2021-December-20-National Merit Students, University Marketing And Communication, East Tennessee State University

ETSU News

Lillian Elder

JOHNSON CITY, Tenn. (Dec. 20, 2021) – Three University School students have been officially recognized by the National Merit Scholarship Corporation (NMSC). Two of the students, Lillian Elder and Zoe Trainor, have been named Commended Students in the 2022 National Merit Scholarship Program. The third student, Shazib Siddiqui, has been named as a Semifinalist. 

Roughly 34,000 Commended Students throughout the nation are being recognized for their academic promise. Although they will not continue to the 2022 competition for National Merit Scholarship awards, Commended Students placed among the …

2021-December-20-Quillen College Of Medicine Announces New Leadership Appointments, University Marketing And Communication, East Tennessee State University

ETSU News

Dr. David Linville

Dr. Linville will serve as senior associate dean and chief of staff at Quillen College of Medicine and associate vice president for Clinical Affairs at ETSU. His new role begins in January 2022.

JOHNSON CITY (Dec. 20, 2021) — Several individuals have been appointed to new leadership roles at East Tennessee State University’s Quillen College of Medicine.

Dr. David Linville will serve as senior associate dean and chief of staff at Quillen College of Medicine and associate vice president for Clinical Affairs at ETSU. His new role begins in January 2022.

“Dr. Linville is well known …

Machine Learning To Simulate And Predict Infection Rates Of Covid-19 Pandemic, Peter Xu

Discovery Undergraduate Interdisciplinary Research Internship

As the covid-19 pandemic brings uncertainty to the medical system, engineering technology comes ahead in an attempt to understand and simulate the impact of it. As the unprecedented pandemic worsens in some states, the medical system encounters severe shortage of medical supplies. To better manage the limited resource nation-wise, the system must foresee the demand in each state and distribute the resources accordingly and prematurely. This project aims to simulate the pandemic and make short-term prediction on daily infections in each state. This forecast would allow the medical system to recognize the states that would require supplies of hospital resource …

Laser Forming Of Compliant Mechanisms And Flat-Foldable Furniture, Daniel Calvin Ames

Theses and Dissertations

Compliant mechanisms are useful for improving existing machines and creating new ones that were not previously possible. They also help us to think of new methods and technologies needed to both improve existing systems as well as manufacture systems that have not been done before. The purpose of this thesis is to show novel implementations of compliant mechanisms into folding systems, and to show new methods for fabricating such mechanisms with nontraditional materials and on difficult scales. Folding systems are shown in furniture applications with chairs, stools, and childcare furniture applications as results of research into how such structures could …

2021-12-20_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted three times a week on Mondays, Wednesdays and Fridays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time …

2021-12-20 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Characterization And Interpretation Of Feldspathic Chromite Assemblages (Fcas) In Four Ordinary Chondrites: An Electron Backscatter Diffraction (Ebsd) Study, Kimberly Louisa Maccini

Dissertations and Theses

Feldspathic Chromite Assemblages (FCAs) are chemically distinctive assemblages rich in Na, Al, and Cr that are found in a variety of chondrites. They consist of concentrations of chromite associated mainly with feldspathic material, either feldspar or the glassy material known as maskelynite. Professor Alan Rubin (2003) has proposed that some FCAs formed by shock melting, but the origin of different types of feldspathic chromite assemblages are unclear and have not been studied with more modern techniques such as Electron Backscatter Electron Diffraction (EBSD).

Here EBSD was used to study FCAs in four metamorphosed ordinary chondrites of different shock stages, including …

Impact Of Semi-Annual Albendazole On Lymphatic Filariasis And Soil-Transmitted Helminth Infection: Parasitological Assessment After 14 Rounds Of Community Treatment, Sébastien D S Pion, Cédric B Chesnais, Gary J Weil, Frédéric Louya, Michel Boussinesq, François Missamou

Open Access Publications

Between October 2012 and October 2015, we conducted a community trial to assess the impact of semi-annual (twice yearly) community treatment with albendazole on lymphatic filariasis in Seke Pembe, a village in the Republic of the Congo. Semi-annual community treatment with albendazole has been continued in the community since October 2015. We conducted an additional parasitological assessment survey in October 2019, 6 months after the 14th round of semi-annual treatment. Between October 2012 and October 2015, Wuchereria bancrofti antigenemia and microfilaremia rates in the community had decreased from 17.3% to 4.7% and from 5.3% to 0.3%, respectively. In October 2019, …

The Relationship Between Acute And Chronic Pancreatitis With Pancreatic Adenocarcinoma: Review, Tamara Alhobayb, Rahul Peravali, Motaz Ashkar

Open Access Publications

No abstract provided.

Blue Christmas, Kara Jasper

Student Work

"Our Savior dwelt among the broken, the directionless, and the melancholy."

Posting about Christmas hope from In All Things - an online journal for critical reflection on faith, culture, art, and every ordinary-yet-graced square inch of God’s creation.

https://inallthings.org/blue-christmas/

Understanding Dyslexia As A Neurological Learning Disability: A Plan For An Instructive Website For Parents And Early Elementary Teachers, Rasma M. Gertners

Masters Projects

The learning disability known as “dyslexia” is often misunderstood by parents and educators. Dyslexia is a life-long, neurodevelopmental disorder characterized by a deficit in phonological awareness and processing. Its likely causes are genetic as well as environmental. Other conditions known to co-occur with dyslexia are Speech and Language Disorder, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, memory problems, and others. In order for children with dyslexia to reach their highest reading potential, the disorder must be remediated before age seven or eight using intensive, explicit reading interventions. Teachers and other education professionals, using prescribed screening instruments, can identify phonological awareness …