Digital Commons Network^™

Feasibility Of Implementing Recommendations To Improve Neglected Tropical Diseases Surveillance And Response In Kenya: A Modified Delphi Study, Arthur K.S. Ng’Etich, Kuku Voyi, Clifford M. Mutero

All Peer-Reviewed Publications

Background: Effective health information systems (HIS) are critical towards achieving timely response to preventive chemotherapy neglected tropical diseases (PC-NTDs) and their eventual elimination. Strengthened HIS enable prompt case detection and effective response to halt disease transmission and prevent probable outbreaks. This study aimed to assess the importance and feasibility of implementing recommendations for improving surveillance core functions, support functions and surveillance attributes concerning PC-NTDs in Kenya. Methods: A descriptive web-based Delphi process comprising of two survey rounds was used to achieve group consensus on the importance of recommended actions and feasibility of their implementation. In the first round, participants were …

An Update On The Distribution Of Glossina (Tsetse Flies) At The Wildlife-Human-Livestock Interface Of Akagera National Park, Rwanda, Richard S. Gashururu, Samuel M. Githigia, Methode N. Gasana, Richard Habimana, Ndichu Maingi, Giuliano Cecchi, Massimo Paone, Weining Zhao, Daniel K. Masiga, James Gashumba

All Peer-Reviewed Publications

Background: Glossina (tsetse flies) biologically transmit trypanosomes that infect both humans and animals. Knowledge of their distribution patterns is a key element to better understand the transmission dynamics of trypanosomosis. Tsetse distribution in Rwanda has not been well enough documented, and little is known on their current distribution. This study determined the current spatial distribution, abundance, diversity, and seasonal variations of tsetse flies in and around the Akagera National Park. Methods: A longitudinal stratified sampling following the seasons was used. Biconical traps were deployed in 55 sites for 6 consecutive days of each study month from May 2018 to June …

Calibration Of The Spearpesticides Bioindicator For Cost-Effective Pesticide Monitoring In East African Streams, Akbar A. Ganatra, Faith Jebiwot Kandie, Ulrike Fillinger, Francis Mcodimba, Baldwyn Torto, Werner Brack, Matthias Liess, Henner Hollert, Jeremias M. Becker

All Peer-Reviewed Publications

Background: Pesticides are washed from agricultural fields into adjacent streams, where even short-term exposure causes long-term ecological damage. Detecting pesticide pollution in streams thus requires the expensive monitoring of peak concentrations during run-off events. Alternatively, exposure and ecological effects can be assessed using the SPEARpesticides bioindicator that quantifies pesticide-related changes in the macroinvertebrate community composition. SPEARpesticides has been developed in Central Europe and validated in other parts of Europe, Australia and South America; here we investigated its performance in East African streams. Results: With minimal adaptations of the SPEARpesticdes index, we successfully characterized pesticide pollution in 13 streams located in …

Pest Interceptions On Imported Fresh Fruits Into South Africa, Livhuwani R. Nnzeru, Phumudzo P. Tshikhudo, Bester T. Mudereri, Moleseng C. Moshobane

All Peer-Reviewed Publications

Global trade through imports and exports of commodities brings an excessive risk of accidental introduction of invasive alien species in many countries. South Africa imports a range of fresh fruits and other commodities to complement its local production. Despite the substantial impacts of these invasive alien species, relatively little is known about the pathways and origins by which these organisms arrive in South Africa. In this study, we analyzed the susceptibility of South Africa to introduced plant-feeding pests detected from imported consignments of fresh fruits into the country over 10 years between 2009 and 2018. The analysis was conducted from …

2021 Taxonomic Update Of Phylum Negarnaviricota (Riboviria: Orthornavirae), Including The Large Orders Bunyavirales And Mononegavirales, Jens H. Kuhn, Scott Adkins, Bernard R. Agwanda, Rim Al Kubrusli, Sergey V. Alkhovsky, Gaya K. Amarasinghe, Tatjana Avšič-Županc, María A. Ayllón, Justin Bahl, Anne Balkema-Buschmann, Matthew J. Ballinger, Christopher F. Basler, Sina Bavari, Martin Beer, Nicolas Bejerman, Andrew J. Bennett, Dennis A. Bente, Éric Bergeron, Brian H. Bird, Carol D. Blair, Kim R. Blasdell, Dag Ragnar Blystad, Jamie Bojko, Wayne B. Borth, Steven Bradfute, Rachel Breyta, Thomas Briese, Paul A. Brown

All Peer-Reviewed Publications

In March 2021, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by four families (Aliusviridae, Crepuscuviridae, Myriaviridae, and Natareviridae), three subfamilies (Alpharhabdovirinae, Betarhabdovirinae, and Gammarhabdovirinae), 42 genera, and 200 species. Thirty-nine species were renamed and/or moved and seven species were abolished. This article presents the updated taxonomy of Negarnaviricota as now accepted by the ICTV.

Immediate Impacts Of Covid-19 Measures On Bean Production, Distribution, And Food Security In Eastern Africa, Eileen Nchanji, Cosmas Kweyu Lutomia, David Karanja

All Peer-Reviewed Publications

The outbreak of coronavirus was expected to adversely affect African countries more than any other region in the world. This assertion was based on the existing conditions in sub-Saharan Africa that exposed the region to the dire consequences of the pandemic. Previously existing underlying conditions that affected the food system include a high dependence on trade for inputs supply, the adverse effects of climate change, crop pests and diseases, poverty, low input use, weak institutions and ineffective policies, and insecurity and conflicts. We collected data from farmers, aggregators, bean research coordinators, and urban and peri-urban consumers in five Eastern African …

Genomic Analysis Reveals Independent Evolution Of Plasmodium Falciparum Populations In Ethiopia, Deriba Abera, Caleb K. Kibet, Teshome Degefa, Lucas Amenga-Etego, Joel L. Bargul, Lemu Golassa

All Peer-Reviewed Publications

Background: Plasmodium falciparum parasite populations in Ethiopia have been experiencing local selective pressures from drugs and immunity, leading to evolutionary adaptation. However, there was a paucity of data on genomic characterization and evolutionary adaptations of P. falciparum isolates from the central area of Ethiopia. Methods: Whole-genome analysis of 25 P. falciparum isolates from central Ethiopia, specifically from West Arsi, were studied to determine their genetic diversity, population structures, and signatures of selection in known drug resistance alleles against global isolates from Cambodia, Thailand, DR Congo, and Malawi. Results: A total of 18,517 high-quality single-nucleotide polymorphisms (SNPs) were identified in Ethiopian …

Evaluation Of Health Surveillance System Attributes: The Case Of Neglected Tropical Diseases In Kenya, Arthur K.S. Ng’Etich, Kuku Voyi, Clifford M. Mutero

All Peer-Reviewed Publications

Background: Control of preventive chemotherapy-targeted neglected tropical diseases (PC-NTDs) relies on strengthened health systems. Efficient health information systems provide an impetus to achieving the sustainable development goal aimed at ending PC-NTD epidemics. However, there is limited assessment of surveillance system functions linked to PC-NTDs and hinged on optimum performance of surveillance system attributes. The study aimed to evaluate surveillance system attributes based on healthcare workers’ perceptions in relation to PC-NTDs endemic in Kenya. Methods: A cross-sectional health facility survey was used to purposively sample respondents involved in disease surveillance activities. Consenting respondents completed a self-administered questionnaire that assessed their perceptions …

Water Immersion Tolerance By Larval Instars Of Stable Fly, Stomoxys Calcitrans, L1758 (Diptera: Muscidae) Impairs The Fitness Performance Of Their Subsequent Stages, Steve B.S. Baleba

All Peer-Reviewed Publications

Background: In holometabolous insects, environmental factors experienced in pre-imaginal life stages affect the life-history traits within that stage and can also influence subsequent life stages. Here, I assessed tolerance to water immersion by the larval instars of the stable fly, Stomoxys calcitrans L. (Diptera: Muscidae) and its impact on the life-history traits of their subsequent life stages. Results: After submerging the three larval instars of S. calcitrans in distilled water, I found that the first instar larvae remained active for longer as compared to the second and third instar larvae. Also, the first instar larvae took a longer period to …

Ehrlichia Spp. Close To Ehrlichia Ruminantium, Ehrlichia Canis, And “Candidatus Ehrlichia Regneryi” Linked To Heartwater-Like Disease In Kenyan Camels (Camelus Dromedarius), Mario Younan, Daniel O. Ouso, Boku Bodha, Edward K. Keitany, Hezron O. Wesonga, Rinah Sitawa, Joshua Kimutai, Wilson Kuria, Wario Sori Sake, Nicholas Svitek, Tobias Landmann, Diba Dida Wako, Jandouwe Villinger

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We present findings from an outbreak of a heartwater-like disease in camels that killed at least 2000 adult animals in Kenya in 2016. Clinical signs included excitability, head pressing, aimless wandering, recumbency, and fast breathing followed by death after about 4 days. The observed morbidity in one herd was 40% with an average mortality of 7.5% in animals that received early antibiotic treatments. In untreated adults, the case fatality rate reached 100%. Gross pathology showed pulmonary edema, pleural exudate, hydrothorax, hydropericardium, ascites, enlarged “cooked” liver, nephrosis, and blood in the abomasum and intestine. Using established PCR-based protocols for tick-borne pathogens, …

Molecular Detection Of Leishmania Donovani, Leishmania Major, And Trypanosoma Species In Sergentomyia Squamipleuris Sand Flies From A Visceral Leishmaniasis Focus In Merti Sub-County, Eastern Kenya, Barrack O. Owino, Jackline Milkah Mwangi, Steve Kiplagat, Hannah Njiriku Mwangi, Johnstone M. Ingonga, Alphine Chebet, Philip M. Ngumbi, Jandouwe Villinger, Daniel K. Masiga, Damaris Matoke-Muhia

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Background: Visceral leishmaniasis (VL) and zoonotic cutaneous leishmaniasis (ZCL) are of public health concern in Merti sub-County, Kenya, but epidemiological data on transmission, vector abundance, distribution, and reservoir hosts remain limited. To better understand the disease and inform control measures to reduce transmission, we investigated the abundance and distribution of sand fly species responsible for Leishmania transmission in the sub-County and their blood-meal hosts. Methods: We conducted an entomological survey in five villages with reported cases of VL in Merti sub-County, Kenya, using CDC miniature light traps and castor oil sticky papers. Sand flies were dissected and identified to the …

Climate Change And Specialty Coffee Potential In Ethiopia, Abel Chemura, Bester Tawona Mudereri, Amsalu Woldie Yalew, Christoph Gornott

All Peer-Reviewed Publications

Current climate change impact studies on coffee have not considered impact on coffee typicities that depend on local microclimatic, topographic and soil characteristics. Thus, this study aims to provide a quantitative risk assessment of the impact of climate change on suitability of five premium specialty coffees in Ethiopia. We implement an ensemble model of three machine learning algorithms to predict current and future (2030s, 2050s, 2070s, and 2090s) suitability for each specialty coffee under four Shared Socio-economic Pathways (SSPs). Results show that the importance of variables determining coffee suitability in the combined model is different from those for specialty coffees …

Mitogenomic Analysis Of Diversity Of Key Whitefly Pests In Kenya And Its Implication To Their Sustainable Management, Fathiya M. Khamis, Fidelis L.O. Ombura, Inusa J. Ajene, Komivi S. Akutse, Sevgan Subramanian, Samira A. Mohamed, Thomas Dubois, Chrysantus M. Tanga, Sunday Ekesi

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Whiteflies (Hemiptera: Aleyrodidae) are devastating agricultural pests of economic importance vectoring pathogenic plant viruses. Knowledge on their diversity and distribution in Kenya is scanty, limiting development of effective sustainable management strategies. The present study is aimed at identifying whitefly pest species present in Kenya across different agroecological zones and establish predictive models for the most abundant species in Africa. Whiteflies were sampled in Kenya from key crops known to be severely infested and identified using 16S rRNA markers and complete mitochondrial genomes. Four whitefly species were identified: Aleyrodes proletella, Aleurodicus dispersus, Bemisia afer and Trialeurodesvaporariorum, the latter being the most …

Assessment Of Surveillance Core And Support Functions Regarding Neglected Tropical Diseases In Kenya, Arthur K.S. Ng’Etich, Kuku Voyi, Clifford M. Mutero

All Peer-Reviewed Publications

Background: Effective surveillance and response systems are vital to achievement of disease control and elimination goals. Kenya adopted the revised guidelines of the integrated disease surveillance and response system in 2012. Previous assessments of surveillance system core and support functions in Africa are limited to notifiable diseases with minimal attention given to neglected tropical diseases amenable to preventive chemotherapy (PC-NTDs). The study aimed to assess surveillance system core and support functions relating to PC-NTDs in Kenya. Methods: A mixed method cross-sectional survey was adapted involving 192 health facility workers, 50 community-level health workers and 44 sub-national level health personnel. Data …

Insect Flower-Visitors Of African Oil Palm Elaeis Guineensis At Different Sites And Distances From Natural Vegetation In Uganda, James Peter Egonyu, Stephen Erisa Sisye, John Baguma, Milton Otema, Gabriel Ddamulira

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This survey aimed at generating information to guide improvement of oil palm fruit-set in Uganda by testing the hypothesis that diversity and abundance of oil palm insect flower-visitors were influenced by sampling site, distance from natural vegetation and flower sex. Sampling was done on male and female oil palm flowers from (i) five oil palm experimental fields in different districts and (ii) oil palm plantations on Bugala Island on Lake Victoria. The plantations on Bugala Island were subdivided into near (0–15 m) and far (100–200 m) from natural vegetation. We recorded 162,677 insects in 23 morpho-species, dominated by weevils in …

Gene Co-Expression Network Analysis Of Trypanosoma Brucei In Tsetse Fly Vector, Kennedy W. Mwangi, Rosaline W. Macharia, Joel L. Bargul

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Background: Trypanosoma brucei species are motile protozoan parasites that are cyclically transmitted by tsetse fly (genus Glossina) causing human sleeping sickness and nagana in livestock in sub-Saharan Africa. African trypanosomes display digenetic life cycle stages in the tsetse fly vector and in their mammalian host. Experimental work on insect-stage trypanosomes is challenging because of the difficulty in setting up successful in vitro cultures. Therefore, there is limited knowledge on the trypanosome biology during its development in the tsetse fly. Consequently, this limits the development of new strategies for blocking parasite transmission in the tsetse fly. Methods: In this study, RNA-Seq …

Transcriptomic Response Of Anopheles Gambiae Sensu Stricto Mosquito Larvae To Curry Tree (Murraya Koenigii) Phytochemicals, Clarence M. Mang’Era, Fathiya M. Khamis, Erick O. Awuoche, Ahmed Hassanali, Fidelis Levi Odhiambo Ombura, Paul O. Mireji

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Background: Insect growth regulators (IGRs) can control insect vector populations by disrupting growth and development in juvenile stages of the vectors. We previously identified and described the curry tree (Murraya koenigii (L.) Spreng) phytochemical leaf extract composition (neplanocin A, 3-(1-naphthyl)-l-alanine, lumiflavine, terezine C, agelaspongin and murrayazolinol), which disrupted growth and development in Anopheles gambiae sensu stricto mosquito larvae by inducing morphogenetic abnormalities, reducing locomotion and delaying pupation in the mosquito. Here, we attempted to establish the transcriptional process in the larvae that underpins these phenotypes in the mosquito. Methods: We first exposed third-fourth instar larvae of the mosquito to the …

Plant Nutrient Quality Impacts Survival And Reproductive Fitness Of The Dengue Vector Aedes Aegypti, Vincent Odhiambo Nyasembe, David Poumo Tchouassi, Martha Njeri Muturi, Christian W.W. Pirk, Catherine L. Sole, Baldwyn Torto

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Background: In a recent study using DNA barcoding, we identified the plants fed upon by four Afro-tropical mosquito species that vector dengue, malaria, and Rift Valley fever. Herein, we have expanded on this study by investigating the role of three of the plants, Pithecellobium dulce (Fabaceae), Leonotis nepetifolia (Lamiaceae), and Opuntia ficus-indica (Cactaceae), on the survival, fecundity, and egg viability of the dengue vector Aedes aegypti. Methods: We tested these effects using females that received (i) an initial three rations of blood meals and (ii) no blood meal at all. Two controls were included: age-matched females fed on glucose solution …

The Pacifican December 2021, University Of The Pacific

All Issues - Student Newspaper, The Pacifican, Pacific Weekly

No abstract provided.

Socially Distant Signing: Why Georgia Should Adopt Remote Will Execution In The Post-Covid World, Jessie Daniel Rankin

Georgia Law Review

In the wake of the COVID-19 pandemic, Georgia Governor Brian Kemp and other state governors issued emergency executive orders authorizing the attestation and execution of wills, trusts, and other testamentary documents through the use of audio-video technology. Most states have traditionally required that such testamentary documents be signed in the physical presence of two or more witnesses to be valid. Georgia’s executive order permits these witnesses to instead observe the signing via video-conferencing software, alleviating the requirement that the witnesses be physically present with the testator. This authorization, however, only exists through this executive order and could lapse or be …

Exegesis: Mark 6:30-44, Younggwang Kim

Masters Theses

Jesus’ feeding the five thousand is the only miracle that the four Gospels commonly recorded among the miracles Jesus Himself performed. The feeding miracle episode is like the gem, which changes light colors slightly depending on how people see it. However, some scholars try to approach it only in a particular direction and partially understand it. Based on the literary-historical-theological methodology, this thesis has a focal point to disclose the compressive and multi-dimensional implications. The exegesis of Mark 6:30-44 begins with the refinement of interpretive methodology. The methodology of this thesis prudently considers both the traditional perspective and recent research. …

Reflip Type: Developing Visual Strategies For Teaching Typography To Collegiate Students With Dyslexia, Brittany D. Strozzo

Masters Theses

In educational facilities today, the approaches to teaching typography to college students with dyslexia are limited. This thesis provides a research-based pedagogy for teaching typography to students in a way that accommodates the visual, processing, and auditory differences present in students with dyslexia. Through the analysis of the learning disability itself, existing material for graphic designers with dyslexia, and current accessibility standards for those with dyslexia, this thesis offers a practical solution to provide a more balanced learning experience for all students, especially those with dyslexia. The aim of this study was to examine the current graphic design standards and …

And The Lord Added To Their Number Daily: A Historical Overview Of The Growth Of The American Evangelical Church, Erica Morgan Wrench

Masters Theses

Serving Special Education Students In The Music Classroom: Accommodating And Advocating For Learners With Exceptionalities, Kathryn Lambert

Masters Theses

Music education programs positively impact the lives of students both socially and emotionally. As the following research suggests, music may have an even greater impact on students with disabilities or exceptionalities. Due to the lack of accessibility, funding, time, training, and other issues, opportunities in music education programs may be limited to groups of students who may not fit the standard music education student profile. As teachers of common core classes may struggle to accommodate students with exceptionalities and may feel as if they are lacking in resources or other needed preparation to adequately serve these students, these struggles are …

Tomb And Temple : The Poet’S Use Of Positive Body Imagery To Communicate Messages Of Psychological Wellbeing, Shelby Elizabeth Poulin

Masters Theses

Mary Oliver writes that imagery is the texture of a poem, and the “detailed, sensory language incorporating images . . . gives the poem dash and tenderness” (Oliver 92). Imagery brings poetry to life, offering the reader a whole-body experience over simple description. Oliver cautions, however, that imagery is powerful and should be used responsibility, further implying that this texture can also become jolting, harsh, or offensive if used incorrectly (Oliver 107-108). With this caution in mind, the purpose of my forty-six poem collection—Tomb and Temple: Letters to the Body—is to use images of the body responsibly, in a way …

Curriculum Framework For Composing And Arranging For Contemporary A Cappella Choirs, Hillary Nicole Goodson-Spear

Masters Theses

As vocalists, it is important for us to understand techniques regarding current styles of vocal composing and arranging including voicing, beat boxing, and body percussion. The success of several mainstream television programs such as Glee and The Sing-Off, popular movies franchises like Pitch Perfect, and groups like Pentatonix and Straight No Chaser, demonstrate the rising popularity of contemporary a cappella music. It also reflects the need to be able to write unique arrangements of traditional or popular songs to keep up with recent trends. Current research suggests that there are very few resources available for music educators to teach this …

Patrick Henry And John Jay: True Patriots And Advocates For Civil And Religious Liberty, Nancy Lynn Greenwood

Masters Theses

Patrick Henry and John Jay had a significant impact in the founding of the United States of America as two of the principal and most influential Founders. They were also among the most public Christians of all the Founding Fathers. Their dedication in their fight for civic and religious freedom as a means to maintaining liberty was well-known. Despite these similarities, they opposed each other on most every major issue. Each envisioned different governments in which to obtain liberty and to keep the American republic. This thesis seeks to explore the differences and similarities between Henry, as a leader of …

Eldre65: Creating A Website For Senior Adults Based Upon User Experience, Rebecca Joy Bozarth

Masters Theses

Geoffrey Chaucer wrote, “Time and tide wait for no man.” He was correct. Aging is universal. It affects all humans in positive and negative ways. From children becoming teens to adults becoming senior adults, each stage of life brings changes and challenges. In one’s forties, menus can become harder to read, hair can fall out, hearing in loud environments can become difficult. Then, in one’s mid-sixties, more difficult challenges can arrive. Health issues such as high blood pressure, diabetes, lung disease can become a regular part of one’s life. Cognition slowness, vision and hearing loss can create difficulties not only …

Analytical Solutions For Advanced Functional Differential Equations With Discontinuous Forcing Terms And Studying Their Dynamical Properties, Amal Khalaf Haydar, Habeeb Kareem Abdullah, Kawther Reyadh Obead

Baghdad Science Journal

This paper aims to find new analytical closed-forms to the solutions of the nonhomogeneous functional differential equations of the nth order with finite and constants delays and various initial delay conditions in terms of elementary functions using Laplace transform method. As well as, the definition of dynamical systems for ordinary differential equations is used to introduce the definition of dynamical systems for delay differential equations which contain multiple delays with a discussion of their dynamical properties: The exponential stability and strong stability

Biological Evaluation And Theoretical Study Of Bi-Dentate Ligand For Amoxicillin Derivative With Some Metal Ions, Sahar S. Hassan, Nidhal M. Hassan, Shaymaa Rajab Baqer, Asmaa M. Saleh

Baghdad Science Journal

In this paper, the complexes of Shiff base of Methyl -6-[2-(diphenylmethylene)amino)-2-(4-hydroxyphenyl)acetamido]-2,2-dimethyl-5-oxo-1-thia-4-azabicyclo[3.2.0]heptane-3-carboxylate (L) with Cobalt(II), Nickel(II), Cupper(II) and Zinc(II) have been prepared. The compounds have been characterized by different means such as FT-IR, UV-Vis, magnetic moment, elemental microanalyses (C.H.N), atomic absorption, and molar conductance. It is obvious when looking at the spectral study that the overall complexes obtained as monomeric structure as well as the metals center moieties are two-coordinated with octahedral geometry excepting Co complexes that existed as a tetrahedral geometry. Hyper Chem-8.0.7 program was employed, after calculating the heat of formation (ΔH°f), binding energy (ΔEb), dipole moment( µ ), …