Digital Commons Network^™

Peonies, Isabel Velasco

The Prairie Light Review

No abstract provided.

Remaining Roots, Carlene English

The Prairie Light Review

No abstract provided.

To Your Knees, Nancy Bandusky

The Prairie Light Review

No abstract provided.

Playing With My Head, Linnea Sardina

The Prairie Light Review

No abstract provided.

Paperclips, Anna Tausz

The Prairie Light Review

No abstract provided.

Times Have Changed, Caroline Bellini

The Prairie Light Review

No abstract provided.

Occasionally Portraiture, D.S. Maolalai

The Prairie Light Review

No abstract provided.

Intersection Effect, Aleksandra Vali

The Prairie Light Review

No abstract provided.

Gratitude

The Prairie Light Review

No abstract provided.

December 1, 2021 Greenmail, University Of Alabama At Birmingham

GreenMail (student newsletter through 2024)

No abstract provided.

Supporting Online Doctoral Student Socialization Through Talk About Writing: A Case Study Of The Short Life Of A Graduate Writing Center, Maureen J. Barney

Faculty & Staff Publications

This dissertation project was a qualitative case study of one writing center for online graduate students, the Graduate Writing Center at Concordia University–Portland. This study focused on synchronous interactions between peer writing consultants and online doctoral students to determine if the synchronous writing support sessions were a space where online doctoral students experienced affective support and socialization experiences. In this research, I analyzed four document sets: seven transcripts of synchronous sessions conducted via Zoom, interviews with three writing consultants and six online doctoral students, anonymous responses to appointment feedback surveys, and my fieldnotes.

Maternal Self-Care Beliefs In Relation To Emotion Regulation Difficulties And Coping Skills, Chloe Poole

Undergraduate Honors Theses

This project is part of a community-based intervention research project in rural Appalachia called Mom Power. Mom Power is a trauma-informed parenting intervention developed to improve mental health and parenting among high-risk mothers with young children. The purpose of this study was to examine the relationship between maternal self-care beliefs, and maternal emotion regulation and coping skills. It was hypothesized that self-care beliefs would be negatively associated with emotion regulation difficulties and positively associated with coping skills. To date, 53 mothers oversampled for psychosocial stressors (e.g., low income, mental health difficulties, trauma histories) have completed self-report questionnaires on self-care, emotion …

Fire And Brimstone: Analyzing Evangelicalism's Burning Of The Bible In Favor Of Literature, Kylee Phalen

Undergraduate Honors Theses

As a cultural staple, the Christian faith has been a defining characteristic of the United States for generations. Religion has moved from the spiritual and become integral to many parts of this society’s social gatherings, artistic outlets, and even businesses. Often rooting itself in conservative values and interpretations of The Bible, Evangelicalism’s beliefs regarding damnation and hell contradicts its sola scriptura theological view. Yet, with The Bible’s near silence on hellish matters when looked at as a whole, the human need to have these gaps filled allowed for literary portrayals of hell and explanations of damnation to become part of …

Effects Of Maternal And Neonatal Hypoxia On The Future Life History Of Daphnia Magna, Rachael Lowman

Undergraduate Honors Theses

Early exposure to hypoxia is related to a variety of physiological and metabolic changes that have lasting effects on organisms’ physiology and life history. We measured the effects of maternal and embryonic mild, intermittent hypoxia on the life history of four clones of microcrustacean Daphnia magna, an emerging model organism for the studies of senescence and longevity. Daphnia individuals were produced parthenogenically, maintained in individual vials, and fed standard algal concentration daily. The cohort consisted of 189 individuals. We measured body size at first reproduction, fecundity (including late-life fecundity peak), offspring sex ratio, and longevity. We found no effect …

Office Of Equity And Inclusion Newsletter - December 2021, Office Of Equity And Inclusion, East Tennessee State University

Office of Equity and Inclusion Newsletters

No abstract provided.

Spatial Concordance Of Dna Methylation Classification In Diffuse Glioma., Niels Verburg, Floris P Barthel, Kevin J Anderson, Kevin C Johnson, Thomas Koopman, Maqsood M Yaqub, Otto S Hoekstra, Adriaan A Lammertsma, Frederik Barkhof, Petra J W Pouwels, Jaap C Reijneveld, Annemieke J M Rozemuller, Jeroen A M Beliën, Ronald Boellaard, Michael D Taylor, Sunit Das, Joseph F Costello, William Peter Vandertop, Pieter Wesseling, Philip C De Witt Hamer, Roel G W Verhaak

Faculty Research 2021

BACKGROUND: Intratumoral heterogeneity is a hallmark of diffuse gliomas. DNA methylation profiling is an emerging approach in the clinical classification of brain tumors. The goal of this study is to investigate the effects of intratumoral heterogeneity on classification confidence.

METHODS: We used neuronavigation to acquire 133 image-guided and spatially separated stereotactic biopsy samples from 16 adult patients with a diffuse glioma (7 IDH-wildtype and 2 IDH-mutant glioblastoma, 6 diffuse astrocytoma, IDH-mutant and 1 oligodendroglioma, IDH-mutant and 1p19q codeleted), which we characterized using DNA methylation arrays. Samples were obtained from regions with and without abnormalities on contrast-enhanced T1-weighted and fluid-attenuated inversion …

Pursuit Of Precision Medicine: Systems Biology Approaches In Alzheimer's Disease Mouse Models., Brianna Gurdon, Catherine Kaczorowski

Faculty Research 2021

Alzheimer's disease (AD) is a complex disease that is mediated by numerous factors and manifests in various forms. A systems biology approach to studying AD involves analyses of various body systems, biological scales, environmental elements, and clinical outcomes to understand the genotype to phenotype relationship that potentially drives AD development. Currently, there are many research investigations probing how modifiable and nonmodifiable factors impact AD symptom presentation. This review specifically focuses on how imaging modalities can be integrated into systems biology approaches using model mouse populations to link brain level functional and structural changes to disease onset and progression. Combining imaging …

Human Macrophage Polarization In The Response To, Alberto Marin, Kristopher Van Huss, John Corbett, Sangjin Kim, Jonathon Mohl, Bo-Young Hong, Jorge Cervantes

Faculty Research 2021

Infection with Mycobacterium leprae, the causative organism of leprosy, is still endemic in numerous parts of the world including the southwestern United States. The broad variation of symptoms in the leprosy disease spectrum range from the milder tuberculoid leprosy (paucibacillary) to the more severe and disfiguring lepromatous leprosy (multibacillary). The established thinking in the health community is that host response, rather than M. leprae strain variation, is the reason for the range of disease severity. More recent discoveries suggest that macrophage polarization also plays a significant role in the spectrum of leprosy disease but to what degree it contributes is …

Supervised Learning With Word Embeddings Derived From Pubmed Captures Latent Knowledge About Protein Kinases And Cancer., Vida Ravanmehr, Hannah Blau, Luca Cappelletti, Tommaso Fontana, Leigh Carmody, Ben D Coleman, Joshy George, Justin Reese, Marcin Joachimiak, Giovanni Bocci, Peter Hansen, Carol J Bult, Jens Rueter, Elena Casiraghi, Giorgio Valentini, Christopher Mungall, Tudor I Oprea, Peter N Robinson

Faculty Research 2021

Inhibiting protein kinases (PKs) that cause cancers has been an important topic in cancer therapy for years. So far, almost 8% of >530 PKs have been targeted by FDA-approved medications, and around 150 protein kinase inhibitors (PKIs) have been tested in clinical trials. We present an approach based on natural language processing and machine learning to investigate the relations between PKs and cancers, predicting PKs whose inhibition would be efficacious to treat a certain cancer. Our approach represents PKs and cancers as semantically meaningful 100-dimensional vectors based on word and concept neighborhoods in PubMed abstracts. We use information about phase …

Aged 539 Graduate Internship Report - Grace Davis High School, Tammy L. Burris

Agricultural Education: Graduate Internship Reports

This internship and project report includes documentation required in meeting the quality criteria for secondary-level programs of instruction in agriculture. The documents are used for the Agriculture Incentive Grant review process at Grace Davis High School conducted by representatives of the California Department of Education. The supporting material includes and overview of he Grace Davis Agriculture program.

Efficacy And Safety Of Avapritinib In Advanced Systemic Mastocytosis: Interim Analysis Of The Phase 2 Pathfinder Trial, Jason Gotlib, Andreas Reiter, Stephen T Oh, Et Al

Open Access Publications

Advanced systemic mastocytosis (AdvSM) is a rare, KIT D816V-driven hematologic neoplasm characterized by mast cell infiltration and shortened survival. We report the results of a prespecified interim analysis of an ongoing pivotal single-arm phase 2 trial (no. NCT03580655 ) of avapritinib, a potent, selective KIT D816V inhibitor administered primarily at a once-daily starting dose of 200 mg in patients with AdvSM (n = 62). The primary endpoint was overall response rate (ORR). Secondary endpoints included mean baseline change in AdvSM-Symptom Assessment Form Total Symptom Score and quality of life, time to response, duration of response, progression-free survival, overall survival, changes …

It’S A Trap: A New Economic Model Addressing American Public Education, Nikhil A. Gulati

Notre Dame Law Review

This Note will argue that, when looking at the quality of a school district, there is some theoretical threshold that determines whether the use of local property tax and zoning by a local government will be effective in increasing the quality of the locality’s schools. This theoretical threshold is conceptually akin to the basic economic idea of a poverty trap. If a locality’s schools are above this quality threshold, the corresponding local government will be able to effectively utilize property taxes and zoning to increase the quality of its schools. However, if it is below the threshold, the local government …

Clemson Commencement Program, December 2021, Clemson University

Clemson Commencement Programs

No abstract provided.

Uncertain Terms, Leah R. Fowler, Jim Hawkins, Jessica L. Roberts

Notre Dame Law Review

Health apps collect massive amounts of sensitive consumer data, including information about users’ reproductive lives, mental health, and genetics. As a result, consumers in this industry may shop for privacy terms when they select a product. Yet our research reveals that many digital health tech companies reserve the right to unilaterally amend their terms of service and their privacy policies. This ability to make one-sided changes undermines the market for privacy, leaving users vulnerable. Unfortunately, the current law generally tolerates unilateral amendments, despite fairness and efficiency concerns. We therefore propose legislative, regulatory, and judicial solutions to better protect consumers of …

Bostock Was Bogus: Textualism, Pluralism, And Title Vii, Mitchell N. Berman, Guha Krishnamurthi

Notre Dame Law Review

In Bostock v. Clayton County, one of the blockbuster cases from its 2019 Term, the Supreme Court held that federal antidiscrimination law prohibits employment discrimination on grounds of sexual orientation and gender identity. Unsurprisingly, the result won wide acclaim in the mainstream legal and popular media. Results aside, however, the reaction to Justice Neil Gorsuch’s majority opinion, which purported to ground the outcome in a textualist approach to statutory interpretation, was more mixed. The great majority of commentators, both liberal and conservative, praised Justice Gorsuch for what they deemed a careful and sophisticated—even “magnificent” and “exemplary”—application of textualist principles, …

Libel By Omission Of Exculpatory Legal Decisions, Eugene Volokh

Notre Dame Law Review

Is it libelous to write that someone has been convicted of a crime, but to fail to mention that the conviction has been reversed? Or to write that someone has been charged, without mentioning the acquittal? The answers, it turns out, are often “yes”; this Article lays out the precedents that so conclude.

Cancelling Capitalism?, Christina P. Skinner

Notre Dame Law Review

Grow the Pie’s defense of capitalism is a tremendous contribution, albeit one which Edmans himself downplays. While the author largely bills his work as one aiming to correct the factual record about profitmaximization— while providing pointers for managers and policymakers—Edmans reaffirms the validity and viability of corporate capitalism as an ideology that, in practice, advances human welfare.

Injecting this viewpoint into the academic debate is critically important at a time when voices of stakeholderists seem the loudest. Sociological research long ago confirmed that societal expectations (as often shaped by academic discourse) have real impact on our social systems and …

Louis Neptune V. Andrew Carey

2021 Decisions

USDC for the District of New Jersey

Kerol Tomlinson V. Attorney General United States

2021 Decisions

Agency

Usa V. Jamille Barksdale

2021 Decisions

USDC for the Eastern District of Pennsylvania