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Articles 781381 - 781410 of 5210812

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Entry Nr. 324 Adriano Gangá, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 324 Adriano Gangá, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 322 Manuel Gangá, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 322 Manuel Gangá, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 326 Mariano Gangá, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 326 Mariano Gangá, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 453 Canuto Houssin, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 453 Canuto Houssin, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 454 Pedro Real Congo, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 454 Pedro Real Congo, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 458 Ikubaje, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 458 Ikubaje, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 457 Carolina Conga, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 457 Carolina Conga, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 460 Manuela De La Guardia, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 460 Manuela De La Guardia, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 463 Manuel Valero, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 463 Manuel Valero, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 461 Manuel Congo, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 461 Manuel Congo, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 465 Román Lucumí, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 465 Román Lucumí, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 466 Telésforo Lucumí, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 466 Telésforo Lucumí, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 464 Emilio Piñeiro, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 464 Emilio Piñeiro, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 467 Cristobal Gangá, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 467 Cristobal Gangá, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 462 José Mina, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 462 José Mina, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 468 Francisco Mina, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 468 Francisco Mina, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 469 Dolores Roca, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 469 Dolores Roca, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 470 Antonio Quesada, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 470 Antonio Quesada, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 472 Poli, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 472 Poli, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 153 Ibrahim, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 153 Ibrahim, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 132 Antson Zizer, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 132 Antson Zizer, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Entry Nr. 172 Richard Pierpoint, Aaron Spencer Fogleman, Robert Hanserd Jan 2022

Entry Nr. 172 Richard Pierpoint, Aaron Spencer Fogleman, Robert Hanserd

500 African Voices

No abstract provided.


Sars-Cov-2: A Master Of Immune Evasion, Alberto Rubio-Casillas, Elrashdy M. Redwan, Vladimir N. Uversky Jan 2022

Sars-Cov-2: A Master Of Immune Evasion, Alberto Rubio-Casillas, Elrashdy M. Redwan, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Viruses and their hosts have coevolved for a long time. This coevolution places both the pathogen and the human immune system under selective pressure; on the one hand, the immune system has evolved to combat viruses and virally infected cells, while viruses have developed sophisticated mechanisms to escape recognition and destruction by the immune system. SARS-CoV-2, the pathogen that is causing the current COVID-19 pandemic, has shown a remarkable ability to escape antibody neutralization, putting vaccine efficacy at risk. One of the virus’s immune evasion strategies is mitochondrial sabotage: by causing reactive oxygen species (ROS) production, mitochondrial physiology is impaired, …


Calcium-Bound S100p Protein Is A Promiscuous Binding Partner Of The Four-Helical Cytokines, Alexey S. Kazakov, Eugenia I. Deryusheva, Maria E. Permyakova, Andrey S. Sokolov, Victoria A. Rastrygina, Vladimir N. Uversky, Eugene A. Permyakov, Sergei E. Permyakov Jan 2022

Calcium-Bound S100p Protein Is A Promiscuous Binding Partner Of The Four-Helical Cytokines, Alexey S. Kazakov, Eugenia I. Deryusheva, Maria E. Permyakova, Andrey S. Sokolov, Victoria A. Rastrygina, Vladimir N. Uversky, Eugene A. Permyakov, Sergei E. Permyakov

Molecular Medicine Faculty Publications

S100 proteins are multifunctional calcium-binding proteins of vertebrates that act intracellularly, extracellularly, or both, and are engaged in the progression of many socially significant diseases. Their extracellular action is typically mediated by the recognition of specific receptor proteins. Recent studies indicate the ability of some S100 proteins to affect cytokine signaling through direct interaction with cytokines. S100P was shown to be the S100 protein most actively involved in interactions with some four-helical cytokines. To assess the selectivity of the S100P protein binding to four-helical cytokines, we have probed the interaction of Ca2+-bound recombinant human S100P with a panel of 32 …


Hepatitis C Virus Infection And Intrinsic Disorder In The Signaling Pathways Induced By Toll-Like Receptors, Elrashdy M. Redwan, Abdullah A. Aljadawi, Vladimir N. Uversky Jan 2022

Hepatitis C Virus Infection And Intrinsic Disorder In The Signaling Pathways Induced By Toll-Like Receptors, Elrashdy M. Redwan, Abdullah A. Aljadawi, Vladimir N. Uversky

Molecular Medicine Faculty Publications

In this study, we examined the interplay between protein intrinsic disorder, hepatitis C virus (HCV) infection, and signaling pathways induced by Toll-like receptors (TLRs). To this end, 10 HCV proteins, 10 human TLRs, and 41 proteins from the TLR-induced downstream pathways were considered from the prevalence of intrinsic disorder. Mapping of the intrinsic disorder to the HCV-TLR interactome and to the TLR-based pathways of human innate immune response to the HCV infection demonstrates that substantial levels of intrinsic disorder are characteristic for proteins involved in the regulation and execution of these innate immunity pathways and in HCV-TLR interaction. Disordered regions, …


Intrinsic Disorder As A Natural Preservative: High Levels Of Intrinsic Disorder In Proteins Found In The 2600-Year-Old Human Brain, Aaron S. Mohammed, Vladimir N. Uversky Jan 2022

Intrinsic Disorder As A Natural Preservative: High Levels Of Intrinsic Disorder In Proteins Found In The 2600-Year-Old Human Brain, Aaron S. Mohammed, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Proteomic analysis revealed the preservation of many proteins in the Heslington brain (which is at least 2600-year-old brain tissue uncovered within the skull excavated in 2008 from a pit in Heslington, Yorkshire, England). Five of these proteins—“main proteins”: heavy, medium, and light neurofilament proteins (NFH, NFM, and NFL), glial fibrillary acidic protein (GFAP), and myelin basic (MBP) protein—are engaged in the formation of non-amyloid protein aggregates, such as intermediate filaments and myelin sheath. We used a wide spectrum of bioinformatics tools to evaluate the prevalence of functional disorder in several related sets of proteins, such as the main proteins and …


A Review Of Distributed Identity Technology In Iot Devices, Myles Perry Jan 2022

A Review Of Distributed Identity Technology In Iot Devices, Myles Perry

Cybersecurity Undergraduate Research Showcase

Distributed identity technology provides solutions to many of the faults currently found in federated identity systems. Applying this technology to internet of things devices has many possible benefits in the realm of device authentication. However, this also provides new challenges not present in existing distributed identity systems. The large number of devices that would enter and leave the system means balancing sybil attack vulnerability and linkage attack vulnerability becomes challenging. Internet of things devices also have less memory and computing power than a standard personal computer or phone. This means any protocol to execute distributed identity in these devices must …


Book Review: Mike Zajko, Telecom Tension: Internet Service Providers And Public Policy In Canada*, Matt Malone Jan 2022

Book Review: Mike Zajko, Telecom Tension: Internet Service Providers And Public Policy In Canada*, Matt Malone

Canadian Journal of Law and Technology

The world of telecommunications, writes Mike Zajko in this timely analysis of internet service providers (ISPs), “is a world many of us have never wondered about, just as we are rarely curious about where our sewage goes or how the electricity grid is configured.” Yet ISPs are not just conduits of fast-traveling light pulses that deliver the internet; they transmit, channel, form, and express a multitude of public policy issues, and they have an important level of agency in the construction and exercise of those policies, too. These dynamics have implications for a large bandwidth of topics relevant to Canadians, …


Brazilian Alliance Perspectives: Towards A Brics Development–Security Alliance?, Zhen 'Arc' Han, Mihaela Papa Jan 2022

Brazilian Alliance Perspectives: Towards A Brics Development–Security Alliance?, Zhen 'Arc' Han, Mihaela Papa

Political Science & Global Affairs Faculty Publications

Scholars studying BRICS (Brazil, Russia, India, China, and South Africa) have traditionally argued that it is a development-focused partnership and not a military/security-based alliance. Yet BRICS members have been deepening their security integration, and Russia and China have been creating an alliance in the background. Although BRICS middle powers have traditionally demonstrated an aversion towards alliances, Brazil actively deepened security cooperation among BRICS members during its BRICS presidency in 2019. How does Brazil view alliances in contemporary power competition? This study examines Brazil’s perceptions by introducing and analysing a new data set of Brazilian expert discourses on alliances since 1990 …


Refracted Memories, Renice Desrosins Jan 2022

Refracted Memories, Renice Desrosins

English Undergraduate Publications

The essay was a project for Professor Marie Hulme’s Creative Nonfiction class. Renice Desrosins also presented her work at the 2022 Sigma Tau Delta English honors conference in Atlanta, Georgia.